association	dataset	threshold value	standardized value
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0703
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	7.37986
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8124
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3016
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3216
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58828
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1706
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22823
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.995
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88364
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8925
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37825
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6026875-MOL2-12-1104-s002.xlsx-List_of_Cancer_Associated_Molec-Tet-MIST1_Cancer_Molecules_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60903
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.092
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1935
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.2553
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34086
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09164
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM63B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07217
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45267
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4538
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49098
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3364
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3598
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46453
Radial spoke stalk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.411
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24498
cilium	GO Cellular Component Annotations 2025	1.0	null
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60566
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08865
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-471-PAX6_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.734
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5033
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.729
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43022
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.7731
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41699
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.703
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6164
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74251
ibrs2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
SH3BGRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13136
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04918
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76036
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.071
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.244
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal testis morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61513
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25255
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06963
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.257
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17409
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37437
GSE203158_5_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158738_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
GSE95182_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43398
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5777
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.30383
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8737
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66713
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21908
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21301
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73261
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44698
PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47969
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.083
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31679
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1624
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4394
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05482
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39629
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5847
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97069
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27473
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.543
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7864
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4077
GSE215132_2_v_0_ptpn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8392
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15623
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8204
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32812
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40118
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.006
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2511
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28749
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.257
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75275
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68734
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr3_119687824_G_A_b38	GTEx eQTL 2025	1.0	1.66487
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61093
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7048
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5943
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0078
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48149
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06924
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2029
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00497
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
AHSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19065
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30838
GET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40203
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.43
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.29272
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9571
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.202
GTEx Thyroid 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	4.84705
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2831
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8081
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81948
axonemal central apparatus assembly	GO Biological Process Annotations 2025	1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45251
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8477
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06079
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72231
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3697
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5152
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.64
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234647_0_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.563
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.364
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2585
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
GSE203158_5_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1209
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1659
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Uterus 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	15.5049
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67587
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATPase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2237
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83554
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27579
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3501
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1496
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.802
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47311
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3576
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.60514
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42951
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.10284
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25693
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03286
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4695
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8059
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8325
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_3_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58331
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4255
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3047
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.24
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8956
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1921
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26353
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7299
GSE99687_2_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50899
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03332
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1514
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3868
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.97231
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0385
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78437
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1916
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99226
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186223,GSE186224_6_v_2_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37441
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02037
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.171
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87788
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.3325
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66854
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.838
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05138
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35779
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05563
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5612
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1705
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27612
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50533
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05186
Reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1723
abnormal brain morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50549
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.39587
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0258
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9871
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44971
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1416
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.111
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62245
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
GSE114232_10_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
496100665_PCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.178
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.257
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3062
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
chr3_119699984_T_C_b38	GTEx eQTL 2025	1.0	1.8982
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.492
cilium movement	GO Biological Process Annotations 2025	1.0	null
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51569
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.637
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67689
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03374
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23869
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77009
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXJ3_FOXJ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.2
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04101
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PITX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61516
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	3.1135
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.493
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17211
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.267
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01293
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10299
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01794
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45822
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9489
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.86239
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
male infertility	IMPC Knockout Mouse Phenotypes	1.0	null
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01713
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.683
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27345
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36612
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4742
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.642257
motile cilium	GO Cellular Component Annotations 2025	1.0	null
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53396
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.934
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24676
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08743
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7395
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41109
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	5.36718
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99373
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9299
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4221
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33848
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31473
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7377
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
PMC4905481-oncotarget-07-11397-s002.xlsx-CtBP1_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36396
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6446
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58897
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55838
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16585
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73279
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48214
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05002
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27891
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3479
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0897
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7829
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80409
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11428
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33323
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
GSE234647_0_v_2_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77377
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34745
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19124
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F2_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0018
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3644
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39215
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
small testis	IMPC Knockout Mouse Phenotypes	1.0	null
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48719
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64414
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12394
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.069
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3252
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	4.12801
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rough endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55627
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14327
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9401
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4277
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03212
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32978
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1136
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.852
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_2_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22429
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14858
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25665
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.081
GTEx AdiposeTissue 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	10.3207
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1995
GSTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70107
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1794
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.009
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0823
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Calprotectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.101
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85267
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04144
PMC11216188-peerj-12-17616-s013.pdf-68-ZBED2_ZBED2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11518656-ADHM-13-0-s002.pdf-96-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6642679-NIHMS1529080-supplement-5.xlsx-Sheet1-Supplementary_Table_4_ATF3_target_genes_in_DN2_B_cells_that_are_also_SLE_disease_DEG_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66802
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13564
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9036
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0809
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphangioleiomyomatosis disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.439
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60049
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3346
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43052
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hippocampal volume in Alzheimer's disease dementia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04603
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10003
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241701_1_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4274
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3793
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19695
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93963
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
abnormal eye morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54705
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3035
increased brain size	IMPC Knockout Mouse Phenotypes	1.0	null
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.5964
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21856
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11191
Signal recognition particle receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00994
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.178
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7848
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82336
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cAMP-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39879
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93077
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01617
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7889
PMC11426526-ppat.1012555.s011.xlsx-Shared_DEG-Shared_DEG_between_MDDC_C91-PL_and_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01942
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17849
MRPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45867
GSE166004_7_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3211
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.005
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04089
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.222
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0679
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04502
Testicular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
e3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6533
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6069
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5795
Ovotestis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24772
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34048
axoneme assembly	GO Biological Process Annotations 2025	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.105
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8642
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18204
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.669
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12559
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5293
YIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54136
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64516
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96572
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8421
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78726
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1289
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8565
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79824
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Corpus callosum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3599
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06933
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
Frond	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537