association	dataset	threshold value	standardized value
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945267
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28812
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51623
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79637
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
proteinaceous extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243879
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.886286
GSE113734_3_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
NONO_02_65	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
Esophageal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2542
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15616
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33344
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02337
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5232
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6789
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01989
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6374
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2927
Attention	HuGE Navigator Gene-Phenotype Associations	1.0	null
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-HT-7877-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099274
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637594
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379499
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96702
bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237513
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89907
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29579
receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41055
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.513743
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Membrane microdomain	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PEO1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
dataset	GeneRIF Biological Term Annotations	1.0	null
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007105
revealing	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06568
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
positive regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.881748
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23551
ES6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9785
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1121
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044329
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.049
breast cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.446935
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869114
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1254
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7487
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.794687
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27748
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
KP3	DepMap CRISPR Gene Dependency	1.0	3.16346
regulation of canonical NF-kappaB signal transduction	GO Biological Process Annotations 2025	1.0	null
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4746
Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672913
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11397
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42177
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75706
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85169
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27015
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
USF1	ENCODE Transcription Factor Targets	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.599675
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.985099
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16656
Lung squamous cell carcinoma_LUSC_TCGA-60-2722-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lmo4_17452977_mcf7_lof_human_gpl570_gds2789	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.103969
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77696
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071927
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07733
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.262755
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91365
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775664
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55752
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.527
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9717
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472315
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52317
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16671
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.696707
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858504
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26253
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043244
Nicotinic acetylcholine-gated receptor, transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
Idiopathic Generalized Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.654618
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25866
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Ripoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95298
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2724
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05827
CAPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06399
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3064
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.647743
adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.794687
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4468
familial	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825339
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07733
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18108
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883493
inhibit	GeneRIF Biological Term Annotations	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
auditory	GeneRIF Biological Term Annotations	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143827
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963332
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29395
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
km3	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00084
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.705525
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.185
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39894
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.226
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83607
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.15361
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.990683
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1554
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05168
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10102
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
frontal	GeneRIF Biological Term Annotations	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.758193
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0763
medial dorsal nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05765
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS-273	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
Chemical carcinogenesis - receptor activation	KEGG Pathways 2026	1.0	null
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02913
poliomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212608
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204029
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866684
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69771
neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160761
SP1	ENCODE Transcription Factor Targets	1.0	null
ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13102
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8889
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.989355
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative	GeneRIF Biological Term Annotations	1.0	null
hydrocortisone_homo sapiens_gpl201_gse21909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68622
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.62597
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833562
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42317
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54334
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906882
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13358
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15189
epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27979
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05794
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073062
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3527
ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6213
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68654
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.780056
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-a_GATA2_R361_Subclone_4_DEGs-SubGene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07733
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT6_02_57	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.9542
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.887036
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
negative regulation of cytokine production involved in inflammatory response	GO Biological Process Annotations 2025	1.0	null
Tramadol	DrugBank Drug Targets	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NOZ	DepMap CRISPR Gene Dependency	1.0	4.86361
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
industrial	GeneRIF Biological Term Annotations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07285
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dendrite	GO Cellular Component Annotations 2025	1.0	null
hsa-miR-3607-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211599
DEL	DepMap CRISPR Gene Dependency	1.0	3.6145
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
S0-EE-Y79N_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27397
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90758
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46551
JC-67-FV32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303506
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5339
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.137147
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826132
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086025
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.522
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77711
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2112
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10763
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12362
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08287
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.868951
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1223
hsa-miR-181a-5p	MiRTarBase microRNA Targets	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.9792
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
opposite	GeneRIF Biological Term Annotations	1.0	null
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796041
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23227
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29059
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638809
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23165
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823963
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717449
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.263722
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464311
Neuropsychological Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.280349
RPMI7951	DepMap CRISPR Gene Dependency	1.0	3.3342
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pathways of neurodegeneration - multiple diseases	KEGG Pathways 2026	1.0	null
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31211
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4555
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14485
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
Mpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906606
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91365
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925096
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.5777
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.300704
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169812
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.965
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
regulation of amyloid-beta formation	GO Biological Process Annotations 2025	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.80891
Hepatocyte growth factor levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96437
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090479
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.15595
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_13786_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.2924
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18113
GSE147240_3_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69794
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	2.22017
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477756
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03271
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866714
mediastinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.431519
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852149
SIN3A	ENCODE Transcription Factor Targets	1.0	null
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52175
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934357
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65783
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386979
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436822
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981984
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108757
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12739
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1929
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974608
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66932
JUN	ChEA Transcription Factor Targets	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HULC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959826
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5198-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
pyloric region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
pick's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.546256
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
negative regulation of tumor necrosis factor superfamily cytokine production	GO Biological Process Annotations 2025	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15544
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.576747
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63558
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.13078
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04361
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.368518
Diseases in Twins	HuGE Navigator Gene-Phenotype Associations	1.0	null
HS683	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05523
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN340	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11174
transporter activity	GO Molecular Function Annotations 2015	1.0	null
newcastle disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.949102
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08335
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
FMNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1481
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
CRCGN012_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26675
orientation	GeneRIF Biological Term Annotations	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
dominant	GeneRIF Biological Term Annotations	1.0	null
products	GeneRIF Biological Term Annotations	1.0	null
demonstrate	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828266
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Human - Motor Cortex - Cluster - PAX6+ CHRFAM7A+ Layer 1 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.78231
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26385
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9196
HOP92	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78746
Schizoaffective disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
NCI-H2291	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00443
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438356
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498048
site of polarized growth	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
regulation of signal transduction	GO Biological Process Annotations 2025	1.0	null
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115432
regulation of protein metabolic process	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Lung squamous cell carcinoma_LUSC_TCGA-85-7844-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9158
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581218
acetylcholine receptor activity	GO Molecular Function Annotations 2023	1.0	null
cellulitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.246098
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865638
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063902
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68703
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42296
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.655836
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1413
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31126
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63593
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11146
hsa-miR-4675	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Up-regulated-Supplementary_Table_S2_Up-reguated_genes_expression_in_MESP1_positive_cells_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9319
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231845
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.872899
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117625
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.196
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524771
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32877
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1332
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072777
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09082
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.41968
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62935
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50345
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987211
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.269
HCC827	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78319
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.887557
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2368
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159658
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
schizoaffective	GeneRIF Biological Term Annotations	1.0	null
Problem Solving	HuGE Navigator Gene-Phenotype Associations	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18823
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09913
schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831765
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
well	GeneRIF Biological Term Annotations	1.0	null
Y79	DepMap CRISPR Gene Dependency	1.0	2.01204
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4764-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9753
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337808
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8581
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7053-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nicotinic acetylcholine receptor signaling pathway	PANTHER Pathways	1.0	null
GSE226770_3_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01598
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97147
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919205
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
dementia	GeneRIF Biological Term Annotations	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Plasma membrane signaling receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9641
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
acetylcholine receptor activity	GO Molecular Function Annotations 2025	1.0	null
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12982
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.569
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283007
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43603
express	GeneRIF Biological Term Annotations	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1935
sparse	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23412
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69819
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2254
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7626
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876029
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1139
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4051
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24736
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73044
Calcium signaling pathway	KEGG Pathways 2026	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887776
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4451
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.438
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.849585
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9149
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92345
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
localization	GO Biological Process Annotations 2015	1.0	null
TARDBP_02_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56156
Rectum adenocarcinoma_READ_TCGA-AF-6136-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181567
rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10624
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
postsynaptic neurotransmitter receptor activity	GO Molecular Function Annotations 2025	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46489
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
region	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23016
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72976
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
ion transport	GO Biological Process Annotations 2015	1.0	null
Wechsler Scales	HuGE Navigator Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.469
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208404
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91849
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18984
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18537
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061598
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	1.46104
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07037
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41309
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77135
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866684
RCC-JW	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03445
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07406
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728152
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0014
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46564
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3635
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921982
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54201
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Neurotransmitter-gated ion-channel transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
intermittent explosive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.909376
stratum spinosum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063632
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.5
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
hiPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
neuronal cell body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
epithelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31143
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.285
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01196
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15876
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11072
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.3676
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68714
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62458
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4713-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880711
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
candidate	GeneRIF Biological Term Annotations	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
regulator	GeneRIF Biological Term Annotations	1.0	null
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08609
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
LU-134-A	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.3002
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303202
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829366
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.898595
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76515
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6477
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38608
Stratum spinosum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.962619
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3989
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51092
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39871
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27912
loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720479
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12785
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.859181
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.484
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.3162
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04909
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67613
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13855
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
GSE206516,GSE206518_2_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3272
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1267
epilepsy	GeneRIF Biological Term Annotations	1.0	null
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
volatile	GeneRIF Biological Term Annotations	1.0	null
KANSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3528
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.848325
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.753297
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09267
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945514
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
Celiac ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
DAUDI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45933
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2025	1.0	null
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
positive regulation of synaptic transmission	GO Biological Process Annotations 2025	1.0	null
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.28956
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076876
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28298
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93194
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33364
metal ion transport	GO Biological Process Annotations 2025	1.0	null
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192251
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.834133
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
TIMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45018
Epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24213
used	GeneRIF Biological Term Annotations	1.0	null
Nicotine Dependence	DisGeNET Gene-Disease Associations	1.0	null
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075813
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43349
alzheimers	GeneRIF Biological Term Annotations	1.0	null
ZNF367	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51658
RELA_02_39	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.78136
conduct disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347879
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5093
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28831
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360036
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853292
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72783
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKN	CCLE Cell Line Gene CNV Profiles	1.0	1.52058
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95741
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
inflammatory	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
15q13 3 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
CRCGN012_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13094
probability	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13016
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.227988
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	3.03605
yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792709
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gilles de la tourette syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.800333
Dementia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.62885
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31349
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91076
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09095
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69322
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.35637
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5047
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.461
NCIH1666	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17714
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18712
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.31687
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2806
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09951
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66458
Pelvic inflammatory disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.293334
A3KAW	DepMap CRISPR Gene Dependency	1.0	5.21607
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84958
locus	GeneRIF Biological Term Annotations	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKCO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.46946
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3763
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.98646
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84456
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67941
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69426
cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054438
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999183
HT1197	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11863
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
hsa-miR-4687-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19588
MRPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10517
been	GeneRIF Biological Term Annotations	1.0	null
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
hsa-miR-4263	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.615227
carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
GSE145639_7_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10353
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indication	GeneRIF Biological Term Annotations	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.67503
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74122
apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6398
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.513417
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08642
COLO-357 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
UBAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10093
M040416	DepMap CRISPR Gene Dependency	1.0	3.10082
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67952
promoter	GeneRIF Biological Term Annotations	1.0	null
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10328
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964796
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperalgesia	DisGeNET Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.776
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.951596
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16366
SIDS Susceptibility Pathways(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
USF2_02_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	8.02514
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92333
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.626909
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
adnfle	GeneRIF Biological Term Annotations	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99048
CRCGN008_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.098
mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764468
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83432
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
RBBP7_02_74	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dendrite morphogenesis	GO Biological Process Annotations 2025	1.0	null
monoatomic ion channel complex	GO Cellular Component Annotations 2025	1.0	null
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39344
hsa-miR-4690-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.202151
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2069
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24723
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
14633610-Table2	GeneSigDB Published Gene Signatures	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80532
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29388
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266913
regulation of long-term synaptic potentiation	GO Biological Process Annotations 2025	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
GSE68229_0_v_1_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7842
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
OACP4C	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.7819
Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084995
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85445
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
negative regulation of amyloid-beta formation	GO Biological Process Annotations 2025	1.0	null
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22599
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07226
negative regulation of canonical NF-kappaB signal transduction	GO Biological Process Annotations 2025	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12773
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.4342
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330278
tctn-b9d complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246407
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0977
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09872
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09038
epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
postsynaptic density	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hsa-miR-325	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83617
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043297
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08387
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39425
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20455
modulation of excitatory postsynaptic potential	GO Biological Process Annotations 2025	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5471
NCIH2171	DepMap CRISPR Gene Dependency	1.0	3.1996
modulation of chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
neuron spine	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.32744
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52745
compounds	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879471
496100429_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17903
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC-827	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683858
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94244
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41491
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18713
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48837
NCIH1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34271
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
psoas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584823
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02442
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10716
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833468
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.739252
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
GTEX-X88G-0226-SM-4GIE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13613
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
autosomal	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880169
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238478
positive regulation of amyloid precursor protein catabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE133516_5_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3166	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01467
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
18842155-Table2	GeneSigDB Published Gene Signatures	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798125
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921902
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
observations	GeneRIF Biological Term Annotations	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.339
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7825
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1907
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69278
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
idiopathic	GeneRIF Biological Term Annotations	1.0	null
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16408
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
peripheral blood lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.207794
BACH1_02_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.56986
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2054
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4680-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.984
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8508
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45983
immune	GeneRIF Biological Term Annotations	1.0	null
oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.993249
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94156
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3463
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stipule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
LN382	Achilles Cell Line Gene Essentiality Profiles	1.0	1.73465
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991746
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198709
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.858
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1006
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
observed	GeneRIF Biological Term Annotations	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.66249
HMGN3_02_45	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.69349
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43891
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.245747
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32106
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51999
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45837
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49197
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06663
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
negative regulation of amyloid precursor protein catabolic process	GO Biological Process Annotations 2025	1.0	null
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43097
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16697
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vaginal discharge	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307033
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.785635
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-c_GATA2_R361_whole_sample_DEGs-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991063
KYSE150	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0299
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35449
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08146
RXRA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31836
innate	GeneRIF Biological Term Annotations	1.0	null
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22357
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2432
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3947
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242768
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01815
cellular process	GO Biological Process Annotations 2015	1.0	null
FOXK2_02_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.03342
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13741
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865019
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.48147
SCC15	CCLE Cell Line Gene CNV Profiles	1.0	2.05089
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.17335
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17053
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0766
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
hsa-miR-4801	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05765
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507457
ACCMESO1	DepMap CRISPR Gene Dependency	1.0	3.64356
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00203
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0601
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936782
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.918096
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.40478
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60268
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38935
PHF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96225
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08329
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94087
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282582
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30312
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31519
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507064
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77503
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36967
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.500007
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1977
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68062
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97794
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33413
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.20163
{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide	DrugBank Drug Targets	1.0	null
Autosomal dominant nocturnal frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.998236
cranial nerve palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.480186
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
growth cone	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84359
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54201
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.764493
A549	DepMap CRISPR Gene Dependency	1.0	6.54211
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89033
lower	GeneRIF Biological Term Annotations	1.0	null
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5357
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.39689
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.515725
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04865
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74646
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
acetylcholine-gated channel complex	GO Cellular Component Annotations 2023	1.0	null
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11409
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1691
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07733
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48134
Acute Myeloid Leukemia_LAML_TCGA-AB-2844-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2787
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866134
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73829
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17025
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.571329
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
MNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39309
YMB-1-E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833562
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879471
mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368998
Lung adenocarcinoma_LUAD_TCGA-69-7974-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
performance	GeneRIF Biological Term Annotations	1.0	null
PKNOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01818
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03868
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5588-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4414
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95115
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60207
neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.353712
phlebitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.418768
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0881
Dementia, Vascular	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12632
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
postsynapse organization	GO Biological Process Annotations 2025	1.0	null
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06846
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046671
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8699
TLE2_02_53	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.47573
JUND	ENCODE Transcription Factor Targets	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912776
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49554
scurvy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.397843
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
ACSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34649
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938928
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24525
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9395_OE_SOX9_SRP201900	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62828
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6566
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29844
transport	GO Biological Process Annotations 2015	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86288
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02705
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
smokers	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61527
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70854
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0997
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
negative regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105593
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98231
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15058
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93657
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1464
nocturnal	GeneRIF Biological Term Annotations	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1383
POU2F2	ENCODE Transcription Factor Targets	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6262
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269174
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375836
regulation of amyloid precursor protein catabolic process	GO Biological Process Annotations 2025	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4597
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.876552
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51266
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1141
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74825
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4741	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91461
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79862
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164947
crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74009
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285507
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29643
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF395_02_69	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.90689
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
synapse organization	GO Biological Process Annotations 2025	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9986
Postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2187
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
NHBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62649
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45007
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.04
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840812
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
axillary bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452969
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219908
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.40034
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07625
ATF3_02_54	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.12928
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMSB15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01922
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829784
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52374
hsa-miR-2355-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.414555
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00847
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86882
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735971
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.51097
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.133
MOLT-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274732
Bipolar Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282976
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39129
implicate	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92624
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.187333
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19652
NCIH23	DepMap CRISPR Gene Dependency	1.0	5.14192
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08828
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059023
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75007
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.888681
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42013
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.445256
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.443292
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.52387
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.8341
acetylcholine-gated channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.289027
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09168
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.752884
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00918
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00196
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60999
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.31759
hsa-miR-512-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Mesolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34683
synaptic transmission, cholinergic	GO Biological Process Annotations 2023	1.0	null
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
PMC8102197-41375_2021_1146_MOESM2_ESM.xlsx-genelists-MOLM13_ChIP_DOT1L_VTP_Dn_150_Krivstov_et_Al_DOT1L	Rummagene Transcription Factor Associations 2026	1.0	null
Epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83721
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70781
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
negative regulation of cytokine production	GO Biological Process Annotations 2025	1.0	null
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
cell junction organization	GO Biological Process Annotations 2025	1.0	null
acetylcholine binding	GO Molecular Function Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4811
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5373
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77096
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11017
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ALOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85915
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45324
endometrial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128166
newborn respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.498085
persons	GeneRIF Biological Term Annotations	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6289
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7842
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
response to amyloid-beta	GO Biological Process Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22084
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19001
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378372
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.759824
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.25931
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301758
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30158
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878643
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83911
positive regulation of ERK1 and ERK2 cascade	GO Biological Process Annotations 2025	1.0	null
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68454
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.448848
significant	GeneRIF Biological Term Annotations	1.0	null
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59371
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
schizoaffective disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05135
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105903
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03658
p50	GeneRIF Biological Term Annotations	1.0	null
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
adolescence-adult electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
LASP1NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80581
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20418
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81137
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2406
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10914
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63685
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.6554
hsa-miR-3200-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Critical COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216132
MEIS2_02_30	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.61471
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.925907
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21207
attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.976744
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3778-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.969848
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03522
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340019
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215637
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
GP2D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.61235
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052204
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4583
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
lewy	GeneRIF Biological Term Annotations	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0487
Blastema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.768612
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
people	GeneRIF Biological Term Annotations	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20737
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.464397
monoatomic ion channel complex	GO Cellular Component Annotations 2023	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309428
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.560847
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13964
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.75935
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74446
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2709
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3234
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1071
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03374
Vascular dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71542
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393746
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
hsa-miR-3137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090528
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0957
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
HMC18	DepMap CRISPR Gene Dependency	1.0	2.32526
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.01015
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14628
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42524
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45613
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12572
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887396
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171535
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853292
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37255
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05261
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42351
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.779816
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918739
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61058
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067704
regulation of supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5134
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4253
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852961
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0799
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.41634
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7152
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257709
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4302
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07299
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20877
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24992
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4311
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4743
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32875
breast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.763226
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058466
hsa-miR-3692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857298
Brain Lower Grade Glioma_LGG_TCGA-W9-A837-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
acetylcholine-gated channel complex	GO Cellular Component Annotations 2025	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2448
plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179973
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40668
chemical synaptic transmission, postsynaptic	GO Biological Process Annotations 2025	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.234891
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.972654
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10363
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2363
RPS6KA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51197
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.272
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00922
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2365
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.960312
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76423
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.48482
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828279
similar	GeneRIF Biological Term Annotations	1.0	null
tick infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.527676
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092719
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-b_GATA2_R361_mutant-cell_DEGs-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44085
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04873
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9825
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82024
Lewy Body Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83218
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
partially	GeneRIF Biological Term Annotations	1.0	null
ERF_02_34	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.93074
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-148a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.714
positive regulation of vasculature development	GO Biological Process Annotations 2025	1.0	null
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50691
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.495
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84351
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0992
involvement	GeneRIF Biological Term Annotations	1.0	null
mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1751
H4	DepMap CRISPR Gene Dependency	1.0	2.67255
Premonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926165
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28887
haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.262755
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10012
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49732
m15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.31006
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7219
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	DepMap CRISPR Gene Dependency	1.0	2.73602
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53885
pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202946
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Perturb_9834_KO_miR31_SRP354225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.353
acetylcholine receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5862
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.103
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6085
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09934
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150466
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84826
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4848-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
generalized	GeneRIF Biological Term Annotations	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53816
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
QGP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.06296
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07625
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3897
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
MDAMB453	DepMap CRISPR Gene Dependency	1.0	2.1367
cellular response to acetylcholine	GO Biological Process Annotations 2025	1.0	null
placenta	HPA Tissue Gene Expression Profiles	-1.0	-0.836134
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974125
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.00595
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7743
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063585
EBC1	DepMap CRISPR Gene Dependency	1.0	5.80768
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721166
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
cation channel complex	GO Cellular Component Annotations 2025	1.0	null
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.079
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.871234
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1312
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4066
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8632
H2591	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78433
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1111
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944922
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51064
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24188
SNU1	DepMap CRISPR Gene Dependency	1.0	2.70959
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5861
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066412
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ligand-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
hsa-miR-676	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.36
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97133
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78699
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34614
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.79448
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36266
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084327
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.832707
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12754469-ab-25-0159-Supplementary-1.pdf-37-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45529
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
impulse control disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324094
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73601
pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155634
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25791
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423436
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5517
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11088
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95011
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Schizophrenia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0174
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9625
asymmetric synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7082-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
OMM25	DepMap CRISPR Gene Dependency	1.0	2.39901
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.821244
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9862
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6608
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52129
tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.787213
deletion	GeneRIF Biological Term Annotations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45286
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19679
venous insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200656
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
Pontocerebellar fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55184
alzheimer disease; dementia; dementia, vascular; lewy body disease; pick disease of the brain	GAD Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN014_HEPG2_3H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03207
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4792
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28535
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_17_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40754
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06895
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943965
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.006977
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98925
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63739
single-organism localization	GO Biological Process Annotations 2015	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61369
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56553
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96881
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01812
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1089
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr15_30617677_A_G_b38	GTEx eQTL 2025	1.0	1.32986
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.147
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70124
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
small intestine	HPA Tissue Gene Expression Profiles	1.0	0.871364
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37568
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74686
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
ETV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34983
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.664372
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071951
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4714
illness	GeneRIF Biological Term Annotations	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
controls	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19985
movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.327375
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266913
krabbe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209248
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06994
acetylcholine-gated channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
positive regulation of angiogenesis	GO Biological Process Annotations 2025	1.0	null
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27376
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.80517
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83299
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627081
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_2393_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.47578
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77573
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
OE33	DepMap CRISPR Gene Dependency	1.0	2.33904
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.163
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
duplication	GeneRIF Biological Term Annotations	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1143
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.57378
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.21326
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44188
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.308
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20544
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04462
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.517649
DDX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05515
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895132
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9469
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20673
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELOVL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02999
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99352
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
acetylcholine-gated monoatomic cation-selective channel activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968229
several	GeneRIF Biological Term Annotations	1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134549
endocytosis	GeneRIF Biological Term Annotations	1.0	null
junctional zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302118
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
vaginal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.131251
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01848
PAX5	ENCODE Transcription Factor Targets	1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042616
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42259
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.411657
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855672
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	DrugBank Drug Targets	1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10177
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15245
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.961
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
regulation of tumor necrosis factor production	GO Biological Process Annotations 2025	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045389
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87964
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
SNU1196	DepMap CRISPR Gene Dependency	1.0	3.67805
copy	GeneRIF Biological Term Annotations	1.0	null
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84844
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_02_67	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.96963
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
bursa of fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663962
external side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30203
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49244
chr15_32093264_G_A_b38	GTEx eQTL 2025	1.0	1.17938
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993573
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.27
SP2_02_42	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.9542
17177833-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150303
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6444
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5803
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1434
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09899
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51897
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
CRCGN008_HEPG2_24H:B16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1631
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.502357
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73696
COLO679	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36249
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.562441
eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.876129
Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
implicated	GeneRIF Biological Term Annotations	1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229756
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19294
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0749
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.837833
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.364085
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988127
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.69474
neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TE9	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24327
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2638
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29698
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1086
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53816
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
membrane raft	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
linked	GeneRIF Biological Term Annotations	1.0	null
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275794
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5545
HCC827	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23532
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
dendrite arborization	GO Biological Process Annotations 2025	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52701
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90616
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39452
SNU601	DepMap CRISPR Gene Dependency	1.0	2.49318
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
duplications	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969441
hsa-miR-372	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838009
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842287
Psychotic Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.53928
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220604
positive regulation of signal transduction	GO Biological Process Annotations 2025	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GH4-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
positive regulation of protein metabolic process	GO Biological Process Annotations 2025	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9089
fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272997
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94381
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169812
Plasma membrane raft	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25516
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
TREX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08856
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.71786
portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834817
TEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49707
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041711
type	GeneRIF Biological Term Annotations	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.64649
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6286
dendritic spine organization	GO Biological Process Annotations 2025	1.0	null
ABCB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6962
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29898
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7576
map	GeneRIF Biological Term Annotations	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3586
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28019
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05008
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58096
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76515
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.689492
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.321545
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02188
variations	GeneRIF Biological Term Annotations	1.0	null
DMS273	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76903
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853292
neurotransmitter receptor complex	GO Cellular Component Annotations 2025	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.955
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12279
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63008
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
velocardiofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211934
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92643
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
modulating	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
duplicated	GeneRIF Biological Term Annotations	1.0	null
ZNF223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90007
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927009
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19665
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458759
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824982
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52325
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.690694
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060356
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
picks	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.119314
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99015
Chlorenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.854788
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
a431	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Wound fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9747
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
CALU3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57594
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3159
C2BBE1	DepMap CRISPR Gene Dependency	1.0	4.36722
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0219
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.903652
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06925
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824427
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.9086
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929571
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8411
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.25748
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32329
RUNX2	ChEA Transcription Factor Targets	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.791044
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.644074
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17238
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34567
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50503
excitatory postsynaptic potential	GO Biological Process Annotations 2025	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90838
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621831
RNF2_02_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.96578
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
T98G	CCLE Cell Line Gene CNV Profiles	1.0	2.09766
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03604
GABPA_01_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	10.0079
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10579
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726918
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09847
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.486266
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992813
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0442
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042916
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.988
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6698
hsa-miR-4677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
negative regulation of tumor necrosis factor production	GO Biological Process Annotations 2025	1.0	null
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-373	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86642
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042754
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03302
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83705
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78476
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245268
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167915
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22487
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70559
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3782
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910705
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
FIP1L1_02_147	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4685
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38331
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
schizophrenia	GAD Gene-Disease Associations	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.478668
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14098
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91365
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196779
thus	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14198
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0488
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5472
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.117
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56251
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43603
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OA-15-DB28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319904
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15008
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
Succinylcholine	DrugBank Drug Targets	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Olivocerebellar fiber system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
OVCA420	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92293
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01826
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996307
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80L-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
Neurotransmitter-gated ion-channel, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8657
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46371
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81759
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
Arthrogryposis multiplex congenita-3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.56478
PMC3470785-NIHMS377161-supplement-3.pdf-153-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858627
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.922149
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr15_30622133_T_C_b38	GTEx eQTL 2025	1.0	1.43132
segmental	GeneRIF Biological Term Annotations	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.670471
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.755258
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
axon	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42828
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.46123
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
T84	DepMap CRISPR Gene Dependency	1.0	2.54769
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1568	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23135
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258355
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18632
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.03119
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.061
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paranoid schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
acetylcholine-gated monoatomic cation-selective channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546136
selfreported	GeneRIF Biological Term Annotations	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946482
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48767
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
specifically	GeneRIF Biological Term Annotations	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234847
williams-beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253127
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.373328
hsa-miR-4731-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70042
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26736
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NR2C2_02_77	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.73697
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44475
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
kwashiorkor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221108
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43497
Golgi cis cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
positive regulation of long-term synaptic potentiation	GO Biological Process Annotations 2025	1.0	null
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38145
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936243
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21665
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
endometritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169091
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32179
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3727
OGDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.757
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1823
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826194
SNU475	DepMap CRISPR Gene Dependency	1.0	5.66105
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53981
SBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80218
acetylcholine-gated channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.49403
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06334
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.692955
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.77027
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3085
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	2.57826
CRCGN016_MCF10A.WT.HP_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43275
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_02_40	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.64386
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YO-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5348
injury	GeneRIF Biological Term Annotations	1.0	null
Plant parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56498
TCCSUP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09162
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4721
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24526
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
biological_process	GO Biological Process Annotations 2015	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22616
LDB1_02_35	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.70044
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
allelic	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941828
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56804
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89463
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952366
evidence	GeneRIF Biological Term Annotations	1.0	null
(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE	DrugBank Drug Targets	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65453
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50175
lobe	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Memantine	DrugBank Drug Targets	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166768
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.640539
epidural abscess	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.652089
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66756
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50772
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987211
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3242
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26815
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein-dna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46728
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875193
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.16422
positive regulation of MAPK cascade	GO Biological Process Annotations 2025	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64503
chr15_30486148_T_C_b38	GTEx eQTL 2025	1.0	1.69672
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
keratinocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.987693
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18656
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056598
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07289
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240956
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1585
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348246
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24412
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516891
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08561
alpha7	GeneRIF Biological Term Annotations	1.0	null
amyloidbeta142	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906834
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52977
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63323
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.71815
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55904
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.60647
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27341
MDA-MB-468	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
parasitic ectoparasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.106859
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2817
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.58771
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7902
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
membrane raft	GO Cellular Component Annotations 2025	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3872
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84025
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.822757
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44835
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-25-UR78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282961
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32179
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
biopsies	GeneRIF Biological Term Annotations	1.0	null
chr15_31379949_A_G_b38	GTEx eQTL 2025	1.0	1.49677
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61248
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.461465
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0858
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68982
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46165
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92223
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2232
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510599
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993821
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06082
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
channel activity	GO Molecular Function Annotations 2015	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703945
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7763
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.133
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parameters	GeneRIF Biological Term Annotations	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67625
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33588
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38608
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.66652
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50468
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0403
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19076
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
lacquer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.852527
risk	GeneRIF Biological Term Annotations	1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9023
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859505
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6677
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
COLO704	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08003
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
excitatory extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5508
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939682
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14628
subunit	GeneRIF Biological Term Annotations	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90402
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12018
Lung adenocarcinoma_LUAD_TCGA-99-8033-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98287
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33089
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061163
nearby	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44218
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1051
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9663
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409731
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835073
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
CDC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3856
chr15_30483748_T_C_b38	GTEx eQTL 2025	1.0	1.69175
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.837414
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2125
Esophageal epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28245
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507457
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42923
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658272
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23807
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Hiv-Associated Neurocognitive Disorder	DisGeNET Gene-Disease Associations	1.0	null
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47804
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.401199
mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090501
Bone_Marrow-hematopoietic stem cell	Tabula Sapiens Gene-Cell Associations	1.0	0.964304
bipolar	GeneRIF Biological Term Annotations	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5009
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09154
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996184
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203619
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853292
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5399
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.863048
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22645
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.128
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.534
disorder	GeneRIF Biological Term Annotations	1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Z8-0626-SM-4AD6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19723
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93117
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06939
Perisynaptic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94571
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29929
hel	HPA Cell Line Gene Expression Profiles	1.0	0.968731
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05202
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665995
calcium ion transport	GO Biological Process Annotations 2025	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.4979
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68884
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS60	Achilles Cell Line Gene Essentiality Profiles	1.0	2.36614
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836149
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182422
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931134
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22047
dendritic spine	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41461
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67887
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68515
ARID3A_02_50	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.78136
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23602
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27515
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221233
FOXA2	ENCODE Transcription Factor Targets	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.978437
Meynert's basal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12005
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6058
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974423
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865777
Tenocyclidine	DrugBank Drug Targets	1.0	null
developing	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69721
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
19699293-TableS6	GeneSigDB Published Gene Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	250.187
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0159
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952041
lateral amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535833
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830093
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565232
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.495
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.9742
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08468
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48458
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20508
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97628
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.303
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.55891
GSE226770_3_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44809
Perturb_3661_KO_EZH2_SRP211748	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.1837
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59999
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ST18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69164
HEC1	DepMap CRISPR Gene Dependency	1.0	2.51625
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21569
Child Development Disorders, Pervasive	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931313
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89666
bronchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377031
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36632
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05342
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.826327
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2986
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11676
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642454
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7293
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60438
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48521
neuron projection arborization	GO Biological Process Annotations 2025	1.0	null
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968882
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.532
receptors	GeneRIF Biological Term Annotations	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.387751
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48959
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.299995
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuroactive ligand signaling	KEGG Pathways 2026	1.0	null
capacity	GeneRIF Biological Term Annotations	1.0	null
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5236
TC-5619	DrugBank Drug Targets	1.0	null
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02305
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76515
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925096
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17097
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35114
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5134
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.90538
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12141
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
LOUNH91	CCLE Cell Line Gene CNV Profiles	1.0	1.54215
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Neurotransmitter-gated ion-channel	InterPro Predicted Protein Domain Annotations	1.0	null
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264396
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.795966
Juvenile Myoclonic Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96605
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BBLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85485
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3149
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385719
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43526
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
nonsmokers	GeneRIF Biological Term Annotations	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318999
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02647
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09513
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
pleural	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38072
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6038
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386593
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27977
plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00547
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
cognition	GO Biological Process Annotations 2025	1.0	null
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347144
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.464397
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha7nicotinic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
dendritic shaft	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
nicotinic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07795
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.973521
mesocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01768
THAP1_02_46	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.39232
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of excitatory postsynaptic potential	GO Biological Process Annotations 2025	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126717
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05426
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03884
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79322
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Major Affective Disorder	DisGeNET Gene-Disease Associations	1.0	null
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.66596
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.277
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219047
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78908
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97103
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99101
hsa-miR-662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83184
AM-38	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07119
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848925
protein-energy malnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.13819
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060225
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35188
hsa-miR-1291	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
channel activity	GO Molecular Function Annotations 2025	1.0	null
regulation of angiogenesis	GO Biological Process Annotations 2025	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29871
targets	GeneRIF Biological Term Annotations	1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45217
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11493
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70636
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ion channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
WHSC1_02_66	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.33985
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
VARENICLINE	DGIdb Drug Targets 2026	1.0	5.2932
AGO2_02_132	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.45943
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.495
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81637
neuron projection organization	GO Biological Process Annotations 2025	1.0	null
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04694
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1845
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.706812
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Arousal	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILF2_02_152	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.5025
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
chrfam7a	GeneRIF Biological Term Annotations	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89341
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91784
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03991
cas1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
proctitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298731
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3377
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4138
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
sartorius	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544549
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.483985
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925096
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.37607
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52626
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85879
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
some	GeneRIF Biological Term Annotations	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55903
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381967
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7726
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.50063
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45208
RNP body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.661185
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3083
PMC9691391-7945884.f3.pdf-138-ENSG00000133250_ZNF414	Rummagene Transcription Factor Associations 2026	1.0	null
pelvic inflammatory disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.756156
regulation of cytokine production involved in inflammatory response	GO Biological Process Annotations 2025	1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61083
TRIM28_02_63	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.89482
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95262
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21428
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
negative regulation of amide metabolic process	GO Biological Process Annotations 2025	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08253
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36001
mesothelioma	GeneRIF Biological Term Annotations	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20881
specify	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2239
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.265
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71007
Dementia, Vascular	HuGE Navigator Gene-Phenotype Associations	1.0	null
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67227
Neurotransmitter-gated ion-channel ligand-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8125
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12735
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32951
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991436
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
affect	GeneRIF Biological Term Annotations	1.0	null
Pyromania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.895
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45655
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42413
EPIBATIDINE	DrugBank Drug Targets	1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13643
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82428
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.65062
root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.207794
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72874
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.04727
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21528
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50773
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15211
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.89616
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.30328
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054925
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13178
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.79886
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
epilepsy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.649323
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cerebral amyloid angiopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
positive regulation of amyloid-beta formation	GO Biological Process Annotations 2025	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.494
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
memory	GO Biological Process Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60952
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10775
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47822
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of ERK1 and ERK2 cascade	GO Biological Process Annotations 2025	1.0	null
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
short-term memory	GO Biological Process Annotations 2025	1.0	null
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
PSIP1_02_158	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.56986
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17575
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inconclusive	GeneRIF Biological Term Annotations	1.0	null
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78201
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26133
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207431
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0369
PTBP1_02_144	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.55459
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pick's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55757
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80163
hsa-miR-20a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.7879
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.66459
Schizophrenic Psychology	HuGE Navigator Gene-Phenotype Associations	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09847
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
facilitates	GeneRIF Biological Term Annotations	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5409
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14355
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
memory	GeneRIF Biological Term Annotations	1.0	null
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372743
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060711
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7101
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
replicated	GeneRIF Biological Term Annotations	1.0	null
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39045
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7399
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8649869-EMMM-13-e14351-s012.xlsx-Common_downregulated_elements-264_common_elements_in_siY_T_SRF_DOWN_and_siATF4_SRF_DOWN_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
SNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34111
uterine fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196085
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24435
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.151
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.744214
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_02_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35755
Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160387
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86277
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-148b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.673321
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86665
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.882341
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36596
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
neuron projection	GO Cellular Component Annotations 2023	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.812932
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2025	1.0	null
sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08126
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.282
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
needed	GeneRIF Biological Term Annotations	1.0	null
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.24818
longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524771
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.373328
Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689226
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167677
hsa-miR-622	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712549
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.953056
shigellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192344
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40465
response to acetylcholine	GO Biological Process Annotations 2025	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8604
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6745
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236921
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lewy Body Disease	DisGeNET Gene-Disease Associations	1.0	null
Keratinocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847913
NFYB_02_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.84549
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542566
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1377
UA-39-TN76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280673
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35268
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875868
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90139
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4965
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0827
mastitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.499614
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44603
CRCGN008_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1177
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46616
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91975
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17561
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43157
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08575
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.291898
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.49185
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951741
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902893
uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474258
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37789
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04365
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14719
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7536
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60558
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27999
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95527
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62733
establishment of localization	GO Biological Process Annotations 2015	1.0	null
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3047
hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.368888
hsa-miR-3135	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826434
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274376
NFE2L1_02_32	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.16993
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
Perturb_8471_Mut_IDH1_SRP099826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.24797
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.649323
19699293-TableS5	GeneSigDB Published Gene Signatures	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08148
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57253
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A3L1-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08008
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cation binding	GO Molecular Function Annotations 2025	1.0	null
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
endophenotype	GeneRIF Biological Term Annotations	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853292
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03298
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30196
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61361
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4894-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27524
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.60041
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4187
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08254
GSE239844_6_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
CADOES1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01124
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.19502
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376202
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92147
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4783
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HE-22-JR80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265052
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95135
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133843
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9401
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.992
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32395
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.341
rat	GeneRIF Biological Term Annotations	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3249
leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.263722
assessment	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39015
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12947
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04732
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42546
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alcohol abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163523
PTBP1_02_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.75489
showing	GeneRIF Biological Term Annotations	1.0	null
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
Autosomal recessive intellectual developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39484
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21895
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.997893
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91365
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337242
Perturb_13783_KD_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53743
Systemic Inflammatory Response Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315588
hsa-miR-2964a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62783
Posterior periventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941738
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.855169
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64309
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
associations	GeneRIF Biological Term Annotations	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52159
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6781
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19247
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.597961
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10047
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dementia	HuGE Navigator Gene-Phenotype Associations	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300468
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
cell body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19852
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20224
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15483
u937	HPA Cell Line Gene Expression Profiles	1.0	0.835142
uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.760742
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06451
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5596
NCIH1915	DepMap CRISPR Gene Dependency	1.0	4.04157
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833562
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10963
Pick Disease Of The Brain	DisGeNET Gene-Disease Associations	1.0	null
ZNF585A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58656
Amyloidosis	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-1825	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7434
polymorphism	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26135
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7067
SF172	Achilles Cell Line Gene Essentiality Profiles	1.0	1.86903
Integrin alphaD-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1921
JHOS4	DepMap CRISPR Gene Dependency	1.0	5.67626
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29011
serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412011
HCC1395	DepMap CRISPR Gene Dependency	1.0	3.45384
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0985
studies	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75974
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
participate	GeneRIF Biological Term Annotations	1.0	null
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45124
Alzheimer disease	KEGG Pathways 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.884167
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6411
whether	GeneRIF Biological Term Annotations	1.0	null
TE10	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16484
antisaccade	GeneRIF Biological Term Annotations	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0275
organic	GeneRIF Biological Term Annotations	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06992
large	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42104
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
humanspecific	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40804
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chromosome 15q13.3 microdeletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.559
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.495
ins-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212761
MSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043659
NFYA_02_76	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.43463
NCIH838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89582
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
Benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0884
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497657
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18579
CRCGN008_HEPG2_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31175
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
PMC4496795-srep12063-s2.xls-STAT1_subnetwork-Gene_symbol_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52911
excitatory extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2023	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343587
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7832
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14532
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43855
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.867878
evoked	GeneRIF Biological Term Annotations	1.0	null
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.829034
Acute Myeloid Leukemia_LAML_TCGA-AB-2988-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.70021
STAT5A_02_72	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.42626
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Receptacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
regulation of amyloid fibril formation	GO Biological Process Annotations 2025	1.0	null
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93789
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82643
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71316
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6703
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.63175
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3134
neuron projection	GO Cellular Component Annotations 2025	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7005
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354084
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
further	GeneRIF Biological Term Annotations	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01812
lack	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76874
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54665
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
hsa-miR-921	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
episodic	GeneRIF Biological Term Annotations	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9366
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54462
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4238
hsa-miR-152	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HR-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264215
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965681
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42544
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361155
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555274
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.6468
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17472
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
SLR25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47674
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.289
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165547
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240996
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36203
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55653
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06962
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.70553
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
thrombophlebitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182375
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35908
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03515
acetylcholine	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80109
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.540055
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91406
hsa-miR-3174	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830702
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11495
HSSCH2	DepMap CRISPR Gene Dependency	1.0	2.91301
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45625
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.44284
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4338
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32933
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
Lung squamous cell carcinoma_LUSC_TCGA-22-5485-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76515
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MORCPR	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39423
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39246
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.60552
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23461
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899484
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03361
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22357
Juvenile myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46181
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01593
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08705
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9723
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.411657
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.27999
extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095987
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29215
FOXP1	ChEA Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86474
reticular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864182
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863409
nachr	GeneRIF Biological Term Annotations	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.47217
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.10613
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1027
regulation of postsynaptic membrane potential	GO Biological Process Annotations 2025	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.734735
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1288
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.888
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96685
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02454
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228497
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6913
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699444
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
versus	GeneRIF Biological Term Annotations	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
extracellular ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65261
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
regulation of MAPK cascade	GO Biological Process Annotations 2025	1.0	null
pathophysiology	GeneRIF Biological Term Annotations	1.0	null
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79213
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
HOP-92	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.47623
bodies	GeneRIF Biological Term Annotations	1.0	null
NFATC1_02_22	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.58496
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527735
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.7906
sensory processing	GO Biological Process Annotations 2025	1.0	null
SMARCA4_02_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087311
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54025
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00547
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.468
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01583
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844035
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271944
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
presynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375136
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22379
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22555
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834702
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.58287
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26409
hsa-miR-499-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
Attention Deficit Disorder with Hyperactivity	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867683
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053852
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.267267
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0153
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.001
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11357
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3638
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835166
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21023
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01601
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MERO95	DepMap CRISPR Gene Dependency	1.0	3.79772
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76036
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846721
Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47761
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.752057
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73636
functionally	GeneRIF Biological Term Annotations	1.0	null
internalization	GeneRIF Biological Term Annotations	1.0	null
pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.278877
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3618
extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174911
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.732
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953896
stomach	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77796
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-f_CEBPA_DEGs-Gene_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
variants	GeneRIF Biological Term Annotations	1.0	null
Perturb_13780_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.0584
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65268
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30437
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38927
japanese encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.918436
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.280349
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52656
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.332121
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17166
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06698
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9702
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944019
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4362
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.81315
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8895
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18018
CTSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23393
mesothelial	GeneRIF Biological Term Annotations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04445
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HGC27	DepMap CRISPR Gene Dependency	1.0	2.74948
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91365
SPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12206
sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00938
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.47911
GSE111247_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34089
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672913
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6917
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905621
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704137
CRCGN014_HEPG2_3H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35605
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ECGI10	DepMap CRISPR Gene Dependency	1.0	2.48675
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18543
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421108
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25675
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0484
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.899209
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
intracellular calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.933
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3551
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0732
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94769
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37762
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925096
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
still	GeneRIF Biological Term Annotations	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7316
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10788
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488667
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996307
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Presenile Dementia	DisGeNET Gene-Disease Associations	1.0	null
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24505
lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33046
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257246
Congenital myasthenic syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921014
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of amide metabolic process	GO Biological Process Annotations 2025	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89653
TMEM98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24459
regulation of nervous system process	GO Biological Process Annotations 2025	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74537
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774419
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06608
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6651
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839955
cotinine	GeneRIF Biological Term Annotations	1.0	null
rectal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.191408
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03592
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24418
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5385
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36677
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09394
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4717
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5811
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.607319
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160387
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86506
uterine luminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8184
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33408
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.936006
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP1_02_41	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.87036
S0-EE-Y6Y9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228888
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199356
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79532
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.45943
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.938
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH-EP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
SNGM	DepMap CRISPR Gene Dependency	1.0	7.08673
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.372
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20009
part	GeneRIF Biological Term Annotations	1.0	null
trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.714189
Integrin alphaX-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71967
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13901
Epilepsy, Generalized	HuGE Navigator Gene-Phenotype Associations	1.0	null
tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Nicotine addiction	KEGG Pathways 2026	1.0	null
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MDAMB468	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74103
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61509
Memory Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_and_DHE_p_0_05_1_5FC-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31781
carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.530693
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364886
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292616
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3098
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant cutis laxa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97888
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1508
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897228
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.8189
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827518
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20515
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chrna7	GeneRIF Biological Term Annotations	1.0	null
postsynaptic neurotransmitter receptor activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134727
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201185
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50663
abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695354
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91374
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52147
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683103
Pick Disease of the Brain	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.930621
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09223
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105759
plasma membrane raft	GO Cellular Component Annotations 2025	1.0	null
chloride channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91183
locked-in syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.822077
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21727
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31689
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2954
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20316
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925096
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16076
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56265
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.46961
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00295
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182153
Membrane raft	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14587
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89201
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598871
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.5933
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
system	GeneRIF Biological Term Annotations	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3713
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81878
conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43107
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
HSF1_02_73	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.45943
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
CYBC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95826
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06841
hsa-miR-3925-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23362
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32767
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222763
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75866
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43145
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1464
adhd ;  attention-deficit hyperactivity disorder	GAD Gene-Disease Associations	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044777
chromosome	GeneRIF Biological Term Annotations	1.0	null
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203122
establish	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4512	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30124
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833562
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.39433
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01301
dendritic spine head	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Inattention	DisGeNET Gene-Phenotype Associations	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32362
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0257
senstive	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63042
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18063
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.615227
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88976
CRCGN008_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0328
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11386
adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02529
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Chromosome Deletion	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6374
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882153
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14975
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44509
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.725692
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7582
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cholinergic synapse	KEGG Pathways 2026	1.0	null
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8118
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
NR4A1_02_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.98868
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567626
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15846
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13165
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8406
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54436
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990105
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43881
CENPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86623
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79091
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.137676
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
EFO27	DepMap CRISPR Gene Dependency	1.0	2.32887
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SIX5_02_78	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.85798
sensory perception	GO Biological Process Annotations 2025	1.0	null
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238706
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34025
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41642
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11967
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39872
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104846
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6207
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3835
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4646
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45436
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13692
vagina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.57042
VMCUB1	CCLE Cell Line Gene CNV Profiles	1.0	1.72343
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.0762
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
Personality Inventory	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31399
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
Perturb_7336_KD_SUGP1_SRP286876	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.36543
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890563
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
number	GeneRIF Biological Term Annotations	1.0	null
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33271
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493