association	dataset	threshold value	standardized value
Perturb_2559_KD_U2AF2_SRP226431	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.84947
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.23531
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1225
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04502
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51586
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43574
Heterochromatin island	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4321
Thymus-fast muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	4.89073
BACH1	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08814
hearing abnormality	HPO Gene-Disease Associations	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.519575
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00422
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3506
aplasia/hypoplasia involving bones of the upper limbs	HPO Gene-Disease Associations	1.0	null
Congenital Hypoplasia Of Lung	DisGeNET Gene-Disease Associations	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57108
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120336_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929081
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17933
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050554
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.85713
abnormality of finger	HPO Gene-Disease Associations	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.87053
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58667
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13835
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
anterior clefting of vertebral bodies	HPO Gene-Disease Associations	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2131_KD_HAPSTR1_SRP377309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36473
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08615
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958824
Ovarian Failure, Premature	HuGE Navigator Gene-Phenotype Associations	1.0	null
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
COLO201	DepMap CRISPR Gene Dependency	1.0	2.55674
Myoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
U251MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.06957
molecular_function	GO Molecular Function Annotations 2015	1.0	null
nicotinic	GeneRIF Biological Term Annotations	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07549
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1731
CL-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYOG_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81907
CRCGN013_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12852
Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	3.97405
nalidixic acid-3668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69054
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04681
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29049
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06693
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Patent foramen ovale	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841114
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.05321
extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.297342
BRD-K06284373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27482
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.23866
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18456
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02724
abnormality of the cervical spine	HPO Gene-Disease Associations	1.0	null
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47559
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.910944
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6201
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054686
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40928
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04304
long face	HPO Gene-Disease Associations	1.0	null
pectus excavatum	HPO Gene-Disease Associations	1.0	null
Freeman-Sheldon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02693
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833604
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48274
Congenital Epicanthus	DisGeNET Gene-Disease Associations	1.0	null
abnormal phrenic nerve morphology	MGI Mouse Phenotype Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872123
MV411	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90422
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66097
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11155
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81242
amniotic constriction ring	HPO Gene-Disease Associations	1.0	null
JMSU1	DepMap CRISPR Gene Dependency	1.0	3.23486
Weight Gain	CTD Gene-Disease Associations	1.0	1.06333
METOCURINE IODIDE	DGIdb Drug Targets 2026	1.0	0.630143
detection	GeneRIF Biological Term Annotations	1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34229
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
Perturb_13965_KD_RB1/TP53/NRP2_SRP373793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.32583
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19639
NOS1	DepMap CRISPR Gene Dependency	1.0	2.65124
Heart Diseases	CTD Gene-Disease Associations	1.0	1.08337
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33092
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40664
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.444263
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049732
CRCGN013_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50473
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
spectrum	GeneRIF Biological Term Annotations	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883824
variants	GeneRIF Biological Term Annotations	1.0	null
flexion contracture	HPO Gene-Disease Associations	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
HS294T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89071
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
BRD-K63853589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07057
periventricular stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19878
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66741
mRNA_CBX8_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DETROIT562	DepMap CRISPR Gene Dependency	1.0	2.23737
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54903
ATF2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
BRD-K51641263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09297
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the clavicle	HPO Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43858
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93741
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29211776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27069
Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00235
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89873
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47633
aplasia/hypoplasia of the lungs	HPO Gene-Disease Associations	1.0	null
Gait Disturbance, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838287
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61664
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03263
Downward Slant Of Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
malignant hyperthermia	HPO Gene-Disease Associations	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20382
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38134
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80038
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05889
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46497
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
abnormal phrenic nerve innervation pattern to diaphragm	MPO Gene-Phenotype Associations	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50822
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80491
Perturb_14574_KO_EP300_SRP336466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37408
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912282
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874535
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
neoplasm of the ear	HPO Gene-Disease Associations	1.0	null
subunit	GeneRIF Biological Term Annotations	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81306
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859566
PMC3102637-1471-2105-12-99-S2.XLSX-11_sigpathways_in_AA_P_0_001-Unnamed_29_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rtpcr	GeneRIF Biological Term Annotations	1.0	null
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.93764
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.11431
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6711
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
Mental Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.644981
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.20186
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19505
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
ptosis	HPO Gene-Disease Associations	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10219
abnormal suckling behavior	MGI Mouse Phenotype Associations 2023	1.0	null
Dysplastic Patella	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_14187_KD_RUNX1_SRP159178	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.10963
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910251
Spinal muscular atrophy type 0	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07564
rhabdomyosarcomas	GeneRIF Biological Term Annotations	1.0	null
Popliteal pterygium syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43214
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82987
D458	DepMap CRISPR Gene Dependency	1.0	2.50628
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06108
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOS	CCLE Cell Line Gene CNV Profiles	1.0	1.59192
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49337
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations	1.0	0.612268
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
muscle contraction	GO Biological Process Annotations 2015	1.0	null
apramycin-2914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42226
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	2.00095
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24631
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37102
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5067
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.32475
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898832
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07954
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.201921
LRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90208
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectus femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
BRD-K24663282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75695
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902114
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
binding	GO Molecular Function Annotations 2015	1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.237684
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17763
mephenytoin-6158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60587
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83929
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Akinesia	DisGeNET Gene-Disease Associations	1.0	null
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.96186
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.914897
phenothrin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82196
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Prestwick-981-3125	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
tanespimycin-221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the talus	HPO Gene-Disease Associations	1.0	null
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65964
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74863
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76382
BRD-K57042334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27739
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04809
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
trunk curl	MPO Gene-Phenotype Associations	1.0	null
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56893
good	GeneRIF Biological Term Annotations	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.978151
Congenital Diaphragmatic Hernia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K02707544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06254
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865254
Skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.742
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.62188
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3407
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23577
Abnormality Of Refraction	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IST-SL2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41886
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
onestep	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857065
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01004
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.97
Highly sodium permeable acetylcholine nicotinic receptors	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the patella	HPO Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
HT1080	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13074
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.01832
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	1.45654
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Congenital myasthenic syndrome 4C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.102
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79516
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.980744
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	164.885
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6687
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.702
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164149
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26062
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
multiple pterygium syndrome, lethal type	OMIM Gene-Disease Associations	1.0	null
Perturb_6859_KD_PUM1/PUM2_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.31296
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
dopamine-491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
partial perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14066
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16774
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03049
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
Thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.719
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08285
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21931
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874185
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56694
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30094
BRD-K65898110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06675
SKMEL3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.89225
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the hip bone	HPO Gene-Disease Associations	1.0	null
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02147
dehydration	MPO Gene-Phenotype Associations	1.0	null
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pointed chin	HPO Gene-Disease Associations	1.0	null
oral cleft	HPO Gene-Disease Associations	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.72562
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28268
BRD-K99412981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41904
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7986
abnormality of the posterior hairline	HPO Gene-Disease Associations	1.0	null
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1009
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
CHRNA1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72288
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27962
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.908
Lethal congenital contracture syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
endplate	GeneRIF Biological Term Annotations	1.0	null
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43833
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180937
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2025	1.0	null
SUCCINYLCHOLINE CHLORIDE	DGIdb Drug Targets 2026	1.0	0.756171
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.5934
Downturned Corners Of Mouth	DisGeNET Gene-Phenotype Associations	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Nuclear cyclin-dependent protein kinase holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
BRD-K57766599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3682
Familial woolly hair syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
aplasia/hypoplasia of the extremities	HPO Gene-Disease Associations	1.0	null
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
2,6-dimethylpiperidine-4543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hindlimb paralysis	MGI Mouse Phenotype Associations 2023	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14321
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54866
trimethylcolchicinic acid-4787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
perinatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42236
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40415
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65788
Malignant hyperthermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
HARA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64689
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927416
PMC11426526-ppat.1012555.s011.xlsx-Shared_DEG-Shared_DEG_between_MDDC_C91-PL_and_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13478_KO_GPR174_SRP400800	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.9809
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34438
Pseudopseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K56441027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15285
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93301
aplasia of the musculature	HPO Gene-Disease Associations	1.0	null
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37957
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
MAP3K1_knockout_245_GSE39240	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6879
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43901
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895768
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27715
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063205
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22669
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43321
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14761
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77784
Palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hunter's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55363
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6611
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97688
GSE172490_5_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21545
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.852554
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27972
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.02336
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90858
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12146_KD_Hdac4_SRP343455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99133
abnormality of the ribs	HPO Gene-Disease Associations	1.0	null
PMC10713402-aging-15-205220-s005.docx-0-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
bicuculline-2139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the intestine	HPO Gene-Disease Associations	1.0	null
GSE158320,GSE183351_2_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypokalemic periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940261
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
acetylcholine-gated channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48084
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1436
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048056
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49506
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29497
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
receptor complex	GO Cellular Component Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76944
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-A08759443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1414
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72146
Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19764912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26234
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19005
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3911
aplasia/hypoplasia of fingers	HPO Gene-Disease Associations	1.0	null
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60153
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.445
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89707
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K62853937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16264
GATA1	ChEA Transcription Factor Targets	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1212
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64437
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29991
BRD-K97445906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14095
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86591
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.956043
Congenital Pectus Excavatum	DisGeNET Gene-Disease Associations	1.0	null
Talipes	DisGeNET Gene-Disease Associations	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
BRD-K81660107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33801
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03939
cyanosis	MPO Gene-Phenotype Associations	1.0	null
BRD-K31510624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02702
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00989
CYCLIN_D1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1708
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1624
Restrictive dermopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
Distal arthrogryposis type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02874
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70806
abnormal muscle physiology	MGI Mouse Phenotype Associations 2023	1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
BRD-K97452545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00556
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836391
abnormality of skeletal physiology	HPO Gene-Disease Associations	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5205
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
Neuronal System	Reactome Pathways 2024	1.0	null
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26293
benperidol-4196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.35439
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34343
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26375
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05655
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7943
orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.663181
Postsynaptic nicotinic acetylcholine receptors	Reactome Pathways 2024	1.0	null
Cocaine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
A1207	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00133
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928434
r3 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.019
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69237
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50096
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.979
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48029
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70896
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8571
SR	GDSC Cell Line Gene Expression Profiles	1.0	2.28187
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3571
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9259
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25028
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82957
Activation of Nicotinic Acetylcholine Receptors	Reactome Pathways 2014	1.0	null
BRD-K61868194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08565
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.94896
NCI-H128	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
FAM168B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7642
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CEBPZ_02_176	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99355
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8272
abnormality of movement	HPO Gene-Disease Associations	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26869
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72567
abnormal neuromuscular synapse morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K50510764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56892
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41609
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55272
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924118
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.38955
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17572
abnormality of skull size	HPO Gene-Disease Associations	1.0	null
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.866249
abnormality of the aortic valve	HPO Gene-Disease Associations	1.0	null
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57886
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30517
morphological abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941062
PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
identify	GeneRIF Biological Term Annotations	1.0	null
decreased fetal movement	HPO Gene-Disease Associations	1.0	null
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
abnormality of the philtrum	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07539
abnormality of the thorax	HPO Gene-Disease Associations	1.0	null
dolichocephaly	HPO Gene-Disease Associations	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	155.256
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929425
single-organism transport	GO Biological Process Annotations 2015	1.0	null
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.622
postsynaptic neurotransmitter receptor activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K95190454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04433
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42608
acetylcholine receptor activity	GO Molecular Function Annotations 2023	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A204	GDSC Cell Line Gene Expression Profiles	1.0	1.49712
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70456
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.61759
myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299092
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_407_OE_DPP4_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18263
palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505102
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02079
umbilical hernia	HPO Gene-Disease Associations	1.0	null
SIMA	DepMap CRISPR Gene Dependency	1.0	2.44296
CHP126	CCLE Cell Line Gene CNV Profiles	1.0	1.82002
cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.730571
Lung Injury_Lung Tissue_GSE1541	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.2373
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
Memory Disorders	CTD Gene-Disease Associations	1.0	1.26794
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971838
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82384
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paralytic squint	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03414
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.29523
TTC549	DepMap CRISPR Gene Dependency	1.0	3.46458
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986105
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
contractures of the joints of the upper limbs	HPO Gene-Disease Associations	1.0	null
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12919
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26489
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042712
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66141
CRCGN009_HEPG2_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69954
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.41241
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53885
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
vertebral clefting	HPO Gene-Disease Associations	1.0	null
RB1_KD_GSE50532_591_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24547
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911002
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894906
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
Primary pulmonary hypoplasia_Lung Tissue_GSE1363	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.864
globe disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58787
levonorgestrel-3708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Striated muscle thin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050608
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64611
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09179
Perturb_2950_KD_Myog_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.68285
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
transporter complex	GO Cellular Component Annotations 2015	1.0	null
Multiple Pterygia	DisGeNET Gene-Phenotype Associations	1.0	null
Microstomia	DisGeNET Gene-Disease Associations	1.0	null
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
PCI-15A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ptosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.0
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
BRD-K77150932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66434
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
abnormal breathing pattern	MPO Gene-Phenotype Associations	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Low Posterior Hairline	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.872721
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aortic dilatation	HPO Gene-Disease Associations	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5227
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29113
abnormality of the labia	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27613
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77319
postsynaptic membrane	GO Cellular Component Annotations 2015	1.0	null
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
SEM	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0632
transient	GeneRIF Biological Term Annotations	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48942
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02175
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32872
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03221
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
myasthenia gravis, neonatal transient	OMIM Gene-Disease Associations	1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0279
TRMT10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84624
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KE-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67987
Myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.664
long fingers	HPO Gene-Disease Associations	1.0	null
kyphosis	HPO Gene-Disease Associations	1.0	null
exostosis of the external auditory canal	HPO Gene-Disease Associations	1.0	null
tomelukast-222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97211
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40984
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54119
SUM229PE	DepMap CRISPR Gene Dependency	1.0	3.32799
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1481
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.07424
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05349
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33369
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.55795
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.112
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23461
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14238
Arthrogryposis	CTD Gene-Disease Associations	1.0	2.88009
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43186
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17514
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63045
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.55375
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
PMC12540438-Data_Sheet_1.PDF-20-ENSG00000189164_ZNF527	Rummagene Transcription Factor Associations 2026	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29187
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87404,GSE87812_2_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975046
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7014
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7047
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71465
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37143
Popliteal Pterygium	DisGeNET Gene-Phenotype Associations	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pierson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61126
Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dislocated radial head	HPO Gene-Disease Associations	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83433
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4397
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7433
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.60234
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29669
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U1-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43594798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3864
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43921
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832228
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42932
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Congenital vertical talus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Cardiovascular organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
contractures, pterygia, and spondylocarpotarsal fusion syndrome 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.984
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12706
Inguinal hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15737
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.269
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53854
hnf1b_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.129285
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06363
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47722
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41183
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29744
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83538
fluphenazine-3194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867767
contractures, pterygia, and spondylocarpotarsal fusion syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CRCGN016_MCF10A.TP53.M_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01249
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49587
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cystic lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.293
Abnormality of prenatal development or birth	ClinVar Gene-Phenotype Associations 2025	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.88989
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20907
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02985
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5789
Malignant Hyperpyrexia Due To Anesthesia	DisGeNET Gene-Disease Associations	1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52705
channel activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K15863674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38057
Absence Of Labia Majora	DisGeNET Gene-Phenotype Associations	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nephrotic syndrome type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07587
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
BRD-K17583574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27442
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.64871
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24932
single-organism process	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3111
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30757
Arthrogryposis multiplex congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.574
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54468
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89794
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23465
vertebral fusion	HPO Gene-Disease Associations	1.0	null
BRD-K59149254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18556
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6897
Autosomal dominant Emery-Dreifuss muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8371
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85233
Telecanthus	DisGeNET Gene-Phenotype Associations	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16377
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35888
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
EBC1	DepMap CRISPR Gene Dependency	1.0	4.51744
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28034
dorsolateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09276
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58597
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95017
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07421
BRD-K92967681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23038
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
abnormal facial shape	HPO Gene-Disease Associations	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	1.0	1.56346
E2F6_02_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.9542
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.638
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	1.75611
low-set, posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
Pointed Chin	DisGeNET Gene-Phenotype Associations	1.0	null
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894104
Klippel-Feil syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
BRD-K60337516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43747
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82995
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71646
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0388
IOSE80	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.81217
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074908
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65462
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
talipes calcaneovalgus	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.09105
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
BRD-K37291743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13926
spi1_17041602_preleukemic_hscs_lof_mouse_gpl1261_gds2411	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.944029
abnormality of the systemic arterial tree	HPO Gene-Disease Associations	1.0	null
abnormality of the scrotum	HPO Gene-Disease Associations	1.0	null
BRD-K90205159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04128
abnormal miniature endplate potential	MPO Gene-Phenotype Associations	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78304
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16518
BRD-K42435091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03627
oligohydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.783526
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23668
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66219
form	GeneRIF Biological Term Annotations	1.0	null
short thorax	HPO Gene-Disease Associations	1.0	null
BRD-K88746179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16815
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5314
abnormal respiratory function	MPO Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26903
lung disease	GWASdb SNP-Disease Associations	1.0	0.222297
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22196
Multiple pterygium syndrome	CTD Gene-Disease Associations	1.0	2.88009
ZNF143	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.823972
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Neuromuscular junction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.615
hsa-miR-4774-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16885
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17235
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05001
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45951
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
postnatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75042
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteogenesis imperfecta type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
ROCURONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.630143
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72932
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86703
aplasia/hypoplasia of the nipples	HPO Gene-Disease Associations	1.0	null
Autosomal dominant distal hereditary motor neuronopathy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830422
BRD-K89377615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06068
SOX9	ChEA Transcription Factor Targets	1.0	null
Spinal Fusion	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13531_KO_Lmna_SRP012097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74923
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
PMC8638098__F6	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73465
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
viral pneumonia	GWASdb SNP-Disease Associations	1.0	0.704601
constructed	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2608
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
increased motor neuron number	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_15293_OE_Fos_SRP304877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.48269
Defect Of Vertebral Segmentation	DisGeNET Gene-Disease Associations	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1731
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25023
phosphoserine	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852127
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
slender finger	HPO Gene-Disease Associations	1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64534
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0404
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32323
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3518
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93606
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6392
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
single-organism localization	GO Biological Process Annotations 2015	1.0	null
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58311
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44778
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81051
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24737
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.00554
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
BRD-K28347985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06309
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
eye and adnexa disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01491
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
talipes	HPO Gene-Disease Associations	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27688
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836351
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13164
decreased embryo size	MPO Gene-Phenotype Associations	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.04423
TOV21G	DepMap CRISPR Gene Dependency	1.0	2.00224
I band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44622
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of calvarial morphology	HPO Gene-Disease Associations	1.0	null
Perturb_3972_KD|Mut_SFPQ|BRAF_SRP258593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.20499
SHFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60002
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09453
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.63288
abnormal skin pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
bad5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36
ACHN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04928
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1873
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Distal arthrogryposis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
while	GeneRIF Biological Term Annotations	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3336
BRD-K08233096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42366
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29387
cystic hygroma	HPO Gene-Disease Associations	1.0	null
Native American myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
BRD-K93488589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01358
Perturb_11565_KD_BAX/BAK_SRP348085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0586
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46944
posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882146
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00684
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2367
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
TTC642	DepMap CRISPR Gene Dependency	1.0	2.94104
large face	HPO Gene-Disease Associations	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83766
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47439
OAW42	DepMap CRISPR Gene Dependency	1.0	2.30331
Neurotransmitter receptors and postsynaptic signal transmission	Reactome Pathways 2024	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29113
micrognathia	HPO Gene-Disease Associations	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26241
bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065257
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
pyrazinamide-4962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.296972
BRD-K35654724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32238
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.3243
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13568
BRD-K26156776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14157
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69977
JL1	CCLE Cell Line Gene CNV Profiles	1.0	1.52062
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00536
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.63823
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
chlorcyclizine-4546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
correlation	GeneRIF Biological Term Annotations	1.0	null
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32875
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
eye disease	GWASdb SNP-Disease Associations	1.0	0.237684
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
Muscle fibre	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LN340	CCLE Cell Line Gene CNV Profiles	1.0	1.64313
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.27611
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.844068
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
short finger	HPO Gene-Disease Associations	1.0	null
thin ribs	HPO Gene-Disease Associations	1.0	null
low posterior hairline	HPO Gene-Disease Associations	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054809
digestion	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal skin pigmentation	MPO Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0101
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953801
Anterior Clefting Of Vertebral Bodies	DisGeNET Gene-Phenotype Associations	1.0	null
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048988
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
abnormality of neural tube closure	HPO Gene-Disease Associations	1.0	null
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.1035
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
BRD-K86956630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04556
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
Congenital Myasthenic Syndromes	DisGeNET Gene-Disease Associations	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067494
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K04918285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04695
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4279
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13656
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25881
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01459
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
STK33_knockdown_50_GSE15151	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47216
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902912
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92142
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	3.03282
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01681
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.929733
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01076
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43223
refractive error	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31845
HEC251	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73963
abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30015
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.458619
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73006
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02359
acetylcholine-gated channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
abnormality of the hip joint	HPO Gene-Disease Associations	1.0	null
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
CDAN1_02_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.39232
Skeletal Muscle Atrophy	DisGeNET Gene-Phenotype Associations	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	2.13874
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5444-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04581
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965651
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.5435
BRD-K03351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3051
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6153
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12589
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.31158
somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
BRD-A06837695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46829
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07636
SNU840	Achilles Cell Line Gene Essentiality Profiles	1.0	1.60018
Muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.789
humans	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_311_KO_CARM1_SRP279319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.2052
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acetylcholine Binding And Downstream Events	Reactome Pathways 2014	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49533
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2853
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55324
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1708
external genital hypoplasia	HPO Gene-Disease Associations	1.0	null
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02148
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38784
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21737
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44632
rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.261599
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04931
MAX_02_192	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
BRD-K88321606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18436
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26983
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65574
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055968
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42563
Peripheral neuropathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43023
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35085
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042303
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
neomycin-5867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32437
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63309
spinal dysraphism	HPO Gene-Disease Associations	1.0	null
BRD-K65729053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32303
PANCURONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.630143
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32218
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798958
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
scrotal hypoplasia	HPO Gene-Disease Associations	1.0	null
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35403
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39046
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1165
Depressed Nasal Ridge	DisGeNET Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56328
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78453
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15929
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.16631
Quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.739
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25566
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aplasia/hypoplasia of the patella	HPO Gene-Disease Associations	1.0	null
abnormality of upper limb bone	HPO Gene-Disease Associations	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05889
Spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
myosmine-3634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51954
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35839
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6651
epicanthus	HPO Gene-Disease Associations	1.0	null
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K88597074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87901
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	2.43393
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
LYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74192
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7014
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08196
abnormality of the scalp	HPO Gene-Disease Associations	1.0	null
abnormality of the nipple	HPO Gene-Disease Associations	1.0	null
abnormal pns synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41793
King Denborough syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5645
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K90045406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27194
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal hand morphology	HPO Gene-Disease Associations	1.0	null
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99003
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64473
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53493
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043013
thymus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.336144
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07192
Hyperplasia	CTD Gene-Disease Associations	1.0	1.59451
abnormalities of placenta or umbilical cord	HPO Gene-Disease Associations	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046403
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal breathing pattern	MGI Mouse Phenotype Associations 2023	1.0	null
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6292
protein complex	GO Cellular Component Annotations 2015	1.0	null
abnormal endplate potential	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN011_HEPG2_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22575
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06625
abnormality of the abdominal wall	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia involving bones of the hand	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76978
COLO741	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24631
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20095
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.01076
Pterygium Of Conjunctiva And Cornea	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
Motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.947
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6427
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.193
Sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.652
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
abnormal miniature endplate potential	MGI Mouse Phenotype Associations 2023	1.0	null
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6612
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edema	DisGeNET Gene-Phenotype Associations	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18452
Distal arthrogryposis type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25444
DNA replication preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80407
MONO-MAC-6	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43683
establishment of localization	GO Biological Process Annotations 2015	1.0	null
abnormal neuron morphology	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the amniotic fluid	HPO Gene-Disease Associations	1.0	null
bufexamac-5090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65201
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.26
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053458
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46047
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18297
pterygium	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1912	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270978
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26293
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590036
MT-ATP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8797
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03268
T84	DepMap CRISPR Gene Dependency	1.0	2.31416
ethisterone-3783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
MED1_OE_GDS4846_11_human_LNCaP prostate cancer cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gait disturbance	HPO Gene-Disease Associations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.64958
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56473
BRD-K02934881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50292
HTK	CCLE Cell Line Gene CNV Profiles	1.0	1.72277
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17025
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K46774516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18745
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33773
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
other phenotype	MPO Gene-Phenotype Associations	1.0	null
COLO783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.94626
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
upper extremity joint dislocation	HPO Gene-Disease Associations	1.0	null
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.536
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76862
abnormal neuromuscular synapse morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
Nicotine Dependence	DisGeNET Gene-Disease Associations	1.0	null
BRD-K31042078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1067
cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.496939
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432608
CRCGN017_MCF10A.TP53.M_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6394
isosorbide-6038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048757
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835183
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0748
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95518
Diaphragm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.862
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75159
muscle	GTEx Tissue Gene Expression Profiles	1.0	2.18987
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23474
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
alveolar rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.610057
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
BRD-K63065496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0009
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86968
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.95171
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30517
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20878
K562	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2096
indometacin-262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09388706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15143
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00302
SJRH30	CCLE Cell Line Gene Expression Profiles	1.0	2.34625
T-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.132
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
BRD-K00631971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24067
uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.249608
Limitation Of Joint Mobility	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-1.28247
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5536
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10094
dysmorphology	GeneRIF Biological Term Annotations	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69398
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66621
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.17519
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94791
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85968
hernia of the abdominal wall	HPO Gene-Disease Associations	1.0	null
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36086
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.295739
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62288
high palate	HPO Gene-Disease Associations	1.0	null
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0953
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.37924
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930144
piroxicam-2252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
RH41	CCLE Cell Line Gene Expression Profiles	1.0	1.60501
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27294
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1199
Scoliosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60565
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45518
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
trypsin	Phosphosite Textmining Biological Term Annotations	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Facial Asymmetry	DisGeNET Gene-Phenotype Associations	1.0	null
Congenital myasthenic syndrome 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.313
BRD-K37741838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16969
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1794
GSE86021_1_v_3_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62P-01A-32R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56816
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.68
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.3052
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76337122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55079
sc71	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
increased variability of skeletal muscle fiber size	MPO Gene-Phenotype Associations	1.0	null
Abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19347
Multiple Pterygium Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44095
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4856
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52133
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19344
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51027
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87177
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07519
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30775
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.094
IGR39	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24925
CADOES1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.16296
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18456
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13314
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Congenital myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.698
Multiple pterygium syndrome Escobar type	ClinVar Gene-Phenotype Associations	1.0	null
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
abnormal fluid regulation	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.06336
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acetylcholine-gated channel complex	GO Cellular Component Annotations 2025	1.0	null
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71251
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68674
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48865
abnormal phrenic nerve morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42971
TOV21G	Achilles Cell Line Gene Essentiality Profiles	1.0	2.09554
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33701
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07373
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16341
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57153
forms	GeneRIF Biological Term Annotations	1.0	null
RPS6KA3	KEA Substrates of Kinases	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17172
contractures of the joints of the lower limbs	HPO Gene-Disease Associations	1.0	null
inguinal hernia	HPO Gene-Disease Associations	1.0	null
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YMB1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50882
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
hsa-miR-4717-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2297
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28268
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.246
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.25947
Perturb_8895_KD_FGD5_SRP281196	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.5475
anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.731973
chrnd	GeneRIF Biological Term Annotations	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27619
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11966
SNU478	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37969
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
lateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74235
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55035
Syndactyly	DisGeNET Gene-Disease Associations	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25459
postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
abnormal hypaxial muscle morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K14707716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36849
Nuchal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26931
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K79329532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01298
exostoses	HPO Gene-Disease Associations	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Myotube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.818
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
SNU1105	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.46954
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
Fetal akinesia deformation sequence	ClinVar Gene-Phenotype Associations 2025	1.0	null
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6095
Benign vascular tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3913
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408212
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21554
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K98961458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3619
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66683
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41397
Gigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25335
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7337
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13461
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99048
nonlethal	GeneRIF Biological Term Annotations	1.0	null
NCOA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5654
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20808
conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576415
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.39855
CORL47	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3866
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	1.56312
conductive hearing impairment	HPO Gene-Disease Associations	1.0	null
abnormality of the forearm	HPO Gene-Disease Associations	1.0	null
hsa-miR-4446-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
fused cervical vertebrae	HPO Gene-Disease Associations	1.0	null
Perturb_2609_KD_CLIP1_SRP212229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54725
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04667
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
abnormality of forearm bone	HPO Gene-Disease Associations	1.0	null
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.4876
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
absence of labia majora	HPO Gene-Disease Associations	1.0	null
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903686
neuromuscular junction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.868368
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69465
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.3445
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1637
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.71273
degradation	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K67408816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55271
Congenital Dislocation Of Radial Head	DisGeNET Gene-Disease Associations	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.78509
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09078
membrane	GO Cellular Component Annotations 2015	1.0	null
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47929
ZNF585B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69488
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15768839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30825
POLH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22551
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
Neuronal System	Reactome Pathways 2014	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37742
neuromuscular	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.84916
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36741
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937477
abnormal embryo size	MPO Gene-Phenotype Associations	1.0	null
joint contractures involving the joints of the feet	HPO Gene-Disease Associations	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36944
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914118
localized skin lesion	HPO Gene-Disease Associations	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Infection by Yersinia enterocolitica_macrophage_GSE2973	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40775
S117	DepMap CRISPR Gene Dependency	1.0	3.43047
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263669
hsa-miR-4494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5127
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24487
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12356
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
BRD-K28135985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94846
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0644
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08746
abnormality of the labia majora	HPO Gene-Disease Associations	1.0	null
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847039
BRD-K35625946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3691
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89376690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27586
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGI-1	GDSC Cell Line Gene Expression Profiles	1.0	1.42386
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.52251
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RB-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12604
Long Philtrum	DisGeNET Gene-Phenotype Associations	1.0	null
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25711
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24729
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
abnormal neuron number	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3917	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
membrane depolarization	GO Biological Process Annotations 2025	1.0	null
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45246
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.054
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1715
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80561
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
abnormality of the diaphragm	HPO Gene-Disease Associations	1.0	null
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71063
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6853
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
prostate	HPA Tissue Gene Expression Profiles	1.0	1.20818
laminin-9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
neoplasm of the outer ear	HPO Gene-Disease Associations	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14147
sulfoxaflor	CTD Gene-Chemical Interactions	1.0	null
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	2.92305
acetylcholine receptor activity	GO Molecular Function Annotations 2015	1.0	null
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68454
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
cardiovascular diseases	GAD Gene-Disease Associations	1.0	null
Thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.55
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0106
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
Pterygium Of Eye	DisGeNET Gene-Disease Associations	1.0	null
Long Face	DisGeNET Gene-Phenotype Associations	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28569
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06879
flexion contracture of finger	HPO Gene-Disease Associations	1.0	null
displacement of the external urethral meatus	HPO Gene-Disease Associations	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
Kennedy's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9311
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37243
acetylcholine-gated channel complex	GO Cellular Component Annotations 2015	1.0	null
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
BRD-K38733341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78427
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21423
edema	HPO Gene-Disease Associations	1.0	null
Hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
Galantamine	DrugBank Drug Targets	1.0	null
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1161
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.82823
Congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Polyhydramnios	DisGeNET Gene-Phenotype Associations	1.0	null
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05156
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.042781
rh30	HPA Cell Line Gene Expression Profiles	1.0	2.38159
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of prenatal development or birth	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70735
abnormality of mouth shape	HPO Gene-Disease Associations	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9623
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42568
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836008
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11136
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16166
Neurotransmitter-gated ion-channel ligand-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Reactome Pathways 2024	1.0	null
spina bifida occulta	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1341
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12356
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35975
abnormality of the curvature of the vertebral column	HPO Gene-Disease Associations	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
respiratory insufficiency	HPO Gene-Disease Associations	1.0	null
hindlimb paralysis	MPO Gene-Phenotype Associations	1.0	null
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.306
hydrops fetalis	HPO Gene-Disease Associations	1.0	null
DECAMETHONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.756171
nefopam-3730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pax37fkhr	GeneRIF Biological Term Annotations	1.0	null
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6933
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
rhombomere 8	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22487
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25718630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00597
MIVACURIUM CHLORIDE	DGIdb Drug Targets 2026	1.0	0.756171
cellular_component	GO Cellular Component Annotations 2015	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94845
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0215
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13428
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48821
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
ligand-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
propidium iodide-6104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Degenerative myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87622
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06045
abnormality of the nasal dorsum	HPO Gene-Disease Associations	1.0	null
BRD-K95192796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60139
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7108
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
Congenital myopathy 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
abnormal skeletal muscle fiber size	MPO Gene-Phenotype Associations	1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
BRD-K11095531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01248
increased neuron number	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32211
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.07447
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053505
neuron projection	GO Cellular Component Annotations 2023	1.0	null
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bilateral Camptodactyly	DisGeNET Gene-Disease Associations	1.0	null
mRNA_SUZ12_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Nicotinic acetylcholine-gated receptor, transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17785
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.739082
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8966
autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.287593
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
less	GeneRIF Biological Term Annotations	1.0	null
abnormality of fluid regulation	HPO Gene-Disease Associations	1.0	null
Congenital myasthenic syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
abnormal skeletal muscle fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.64964
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Gastrocnemius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.01
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958165
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01034
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
17210682-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the spinal cord	HPO Gene-Disease Associations	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal neurite morphology	MPO Gene-Phenotype Associations	1.0	null
Fetal akinesia deformation sequence syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.449
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04883
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K27401646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11512
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71306
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99428
abnormality of female external genitalia	HPO Gene-Disease Associations	1.0	null
extracellular	GeneRIF Biological Term Annotations	1.0	null
Diaphragmatic Eventration	DisGeNET Gene-Disease Associations	1.0	null
BRD-K19457629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13017
KYSE520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5923
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40099
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208481
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90007
Learning Disorders	CTD Gene-Disease Associations	1.0	1.04941
MYC_Activation - 2 hours_GDS2025_723_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
useful	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
flexion contracture of digit	HPO Gene-Disease Associations	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7372
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68672
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347144
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39763
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06301
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90803
Tcof1_KD_GDS998_155_mouse_neuroblastoma N1E-115 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58305
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46569
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76357
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.684735
Reduced Fetal Movement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06413
Perturb_15861_KD_ETS1_SRP270313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94464
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49357
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	SynGO Synaptic Gene Annotations	1.0	null
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41768
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52693
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02829
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933163
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1686
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21178
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90594
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.33337
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1149
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Contractile fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.659
abnormal phrenic nerve innervation pattern to diaphragm	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02022
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.988
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.6667
HAL-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82834
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.087
MutSbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.222297
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185313
Nevus	DisGeNET Gene-Disease Associations	1.0	null
KLHDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32471
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.62025
Perturb_8504_KO_Hr_SRP200420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.77081
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34403
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SNUC2A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.38472
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926412
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01718
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.41114
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54633
PMC7021771-41467_2020_14684_MOESM10_ESM.xlsx-CASZ1b_regulated_MYOD_targets-GENE_SYMBOL_MYOD1	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31057
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90401
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1582
HS578T	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20507
Perturb_8240_KD_SF3B4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.41837
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884726
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35557
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95013
FOXP1	ChEA Transcription Factor Targets	1.0	null
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
hydrocortisone-5284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08427390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10265
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844807
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825437
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38162
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47349
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38398
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41208
excitatory extracellular ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34685
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05569
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46464
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16377
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73377
ST18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67022
Transmission across Chemical Synapses	Reactome Pathways 2024	1.0	null
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798125
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05601
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048469
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
positional foot deformity	HPO Gene-Disease Associations	1.0	null
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77007746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39206
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
abnormality of temperature regulation	HPO Gene-Disease Associations	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Morphological Abnormality Of The Gastrointestinal Tract	DisGeNET Gene-Phenotype Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71381
prazosin-6475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K40927841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.186
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.88896
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6301
abnormal cervical curvature	HPO Gene-Disease Associations	1.0	null
abnormal somatic motor system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K16673836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.47879
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04732
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC1A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9011
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54389
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33394
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53228
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17387
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04776
CRCGN014_HEPG2_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25924
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.652087
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.13483
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
BRD-K55940699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25736
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06895
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921368
protein binding	GO Molecular Function Annotations 2015	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3926
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
hsa-miR-3159	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6162
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06425
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31724
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94733
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06895
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15428
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
sulfamethoxypyridazine-4733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33577
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94592
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092156
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24001
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4878
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86918
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
finasteride-3641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.673
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
role of nicotinic acetylcholine receptors in the regulation of apoptosis	Biocarta Pathways	1.0	null
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33068
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99447
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961092
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2884
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979181
medrysone-4266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.04924
abnormality of the face	HPO Gene-Disease Associations	1.0	null
specific	GeneRIF Biological Term Annotations	1.0	null
Intrinsic component of nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.369
Kyphosis Deformity Of Spine	DisGeNET Gene-Phenotype Associations	1.0	null
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
camp	Phosphosite Textmining Biological Term Annotations	1.0	null
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Congenital Hypoplasia Of Penis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04271
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251718
Lethal multiple pterygium syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15089
Whipple's Disease_macrophage_GSE16180	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.61464
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	2.11559
BRD-K81897236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87503
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21767
diflunisal-1490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
HT55	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33156
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30499
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
Perturb_2045_KO_ZRSR2_SRP050493	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33132
Perturb_7959_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.9341
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86174
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.282372
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.62419
acetylcholine-gated monoatomic cation-selective channel activity	GO Molecular Function Annotations 2025	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.258
hsa-miR-4675	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormality of body height	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19235
abnormal spinal cord morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13835
Autosomal recessive chronic granulomatous disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4959
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92643
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66833
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.44576
interphalangeal joint contracture of finger	HPO Gene-Disease Associations	1.0	null
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78221
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81064
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54862
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23509
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
Familial periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45778
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50015
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05349
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33162
Perturb_7086_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6416
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
abdominal wall defect	HPO Gene-Disease Associations	1.0	null
Intranuclear rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04074
BRD-K73730918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05453
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43564
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Increased Susceptibility To Fractures	DisGeNET Gene-Phenotype Associations	1.0	null
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18696
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24922
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2567
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1524
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984386
Generalized dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
channel activity	GO Molecular Function Annotations 2023	1.0	null
abnormal location of ears	HPO Gene-Disease Associations	1.0	null
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5212
proton-transporting two-sector ATPase complex, proton-transporting domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
BRD-K05250921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09965
camptodactyly of toe	HPO Gene-Disease Associations	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47928
neoplasm by anatomical site	HPO Gene-Disease Associations	1.0	null
Polycystic Ovary Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3426
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44217
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.37915
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25644
HS695T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05479
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45833
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HR-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal form of the vertebral bodies	HPO Gene-Disease Associations	1.0	null
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal dendrite morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Pena-Shokeir Syndrome	DisGeNET Gene-Disease Associations	1.0	null
finger syndactyly	HPO Gene-Disease Associations	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984386
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533065
Thoracic spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28963
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64595
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11351
Xeroderma pigmentosum group E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03509
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79771
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
betonicine-6063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rib fusion	HPO Gene-Disease Associations	1.0	null
Leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.066
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90942
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89245
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993089
Skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.153
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35086
fetal akinesia sequence	HPO Gene-Disease Associations	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8395
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1313
CMK115	DepMap CRISPR Gene Dependency	1.0	3.62247
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97636
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07496
thin diaphragm muscle	MGI Mouse Phenotype Associations 2023	1.0	null
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
SKRC20	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45594
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53148
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16341
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82067
BRD-K08006576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27213
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6463
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62653
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.378
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20587
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22821
Axillary Pterygium	DisGeNET Gene-Phenotype Associations	1.0	null
joint dislocation	HPO Gene-Disease Associations	1.0	null
Satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
SLC25A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56754
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46004
popliteal pterygium	HPO Gene-Disease Associations	1.0	null
BRD-K92789454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7598
hypotonia-cystinuria syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol-387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88009
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.44099
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00779
SKMEL2	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.82425
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
cyanosis	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89979
Long Narrow Head	DisGeNET Gene-Disease Associations	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44789
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
BRD-K85357344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42508
muscle contraction	GO Biological Process Annotations 2023	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.54896
cell part	GO Cellular Component Annotations 2015	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.04989
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5047
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64784
HEC6	DepMap CRISPR Gene Dependency	1.0	2.09681
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5355-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
Hernia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-A02799884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75357
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
possible	GeneRIF Biological Term Annotations	1.0	null
BRD-K60389305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46952
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42201
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41626
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
Thrombophilia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.053745
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966015
abnormal oxygen level	MPO Gene-Phenotype Associations	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3587
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
facial asymmetry	HPO Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10839
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07192
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
abnormality of lower limb bone	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23765
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08241
Perturb_15023_KD_RelA_SRP078053	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.64023
Perturb_7031_KD_Casz1_SRP038989	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73729
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968488
hsa-miR-1228	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00314
MAZ	ENCODE Transcription Factor Targets	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K04968881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28242
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
intercrural pterygium	HPO Gene-Disease Associations	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61779
hsa-miR-4741	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98905
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95623
SCS214	DepMap CRISPR Gene Dependency	1.0	4.0033
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21529
NB12	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62571
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
hip dislocation	HPO Gene-Disease Associations	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.048295
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
CRCGN017_MCF10A.WT.HP_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2458
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53553
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51073
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5527
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.914278
Perturb_15404_KD_NRP2_SRP377764	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.16762
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38685
BRD-K27638063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2119
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
BRD-K73213708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43629
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2023	1.0	null
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35841
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053273
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15765
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
collagen type vi trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.882399
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962079
synaptic membrane	GO Cellular Component Annotations 2015	1.0	null
PMC5054603__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Neostriatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39699
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02184
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48401
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
abnormal skeletal muscle morphology	MPO Gene-Phenotype Associations	1.0	null
TUBOCURARINE CHLORIDE	DGIdb Drug Targets 2026	1.0	0.756171
webbed neck	HPO Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48513
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35759
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.343
Hyperkalemic periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9518
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.48115
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248203
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38611
Distal arthrogryposis type 5D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.295
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal dendrite morphology	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I4-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aortic Aneurysm	DisGeNET Gene-Disease Associations	1.0	null
pressure	GeneRIF Biological Term Annotations	1.0	null
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
PMC7595190-41598_2020_75453_MOESM6_ESM.xlsx-MLL_EFS_groups_DEGs-Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07481069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20753
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
several psychiatric disorders	GAD Gene-Disease Associations	1.0	null
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.454
lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18712
C2C12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08086
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	3.35063
Ankle flexion contracture	ClinVar Gene-Phenotype Associations 2025	1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040764
KYM1	CCLE Cell Line Gene CNV Profiles	1.0	1.92396
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.65719
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864344
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00526
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the hard palate	HPO Gene-Disease Associations	1.0	null
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046163
CTCF	ENCODE Transcription Factor Targets	1.0	null
Perturb_8870_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43248
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10544
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081358
contractures, pterygia, and spondylocarpotarsal fusion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.652
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0239
hypoplastic male external genitalia	HPO Gene-Disease Associations	1.0	null
abnormality of joint mobility	HPO Gene-Disease Associations	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21718
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07682
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.1522
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82989
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90594
Perturb_4426_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.61312
DLD1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.44288
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36914
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07161
limitation of joint mobility	HPO Gene-Disease Associations	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.971855
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	2.23279
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2562
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3347
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09448
diagnosis	GeneRIF Biological Term Annotations	1.0	null
arachnodactyly	HPO Gene-Disease Associations	1.0	null
hsa-miR-510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66544
neurotransmitter receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K29838935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02899
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
IZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928018
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01376
BRD-K03733288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23097
abnormal diaphragm morphology	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12016
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16059
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889834
BRD-K43384508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42351
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26816
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81867
BRD-K94411351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4098
hypoplastic nipples	HPO Gene-Disease Associations	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
BRD-K08659289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06812
rms	GeneRIF Biological Term Annotations	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909405
Perturb_565_KO_NRAS_SRP158623	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59734
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58514
abnormality of the radial head	HPO Gene-Disease Associations	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regional abnormality of skin	HPO Gene-Disease Associations	1.0	null
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97835
Long Clavicle	DisGeNET Gene-Phenotype Associations	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74728
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8179
CRCGN009_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19212
abnormality of the umbilicus	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3187
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82137
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
Integral component of nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83186
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K19808762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07769
orlistat-6415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46887
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12224
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929081
Asynchronous muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
spina bifida	HPO Gene-Disease Associations	1.0	null
neuron projection	GO Cellular Component Annotations 2025	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30547
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17834
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_3H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01894
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47726
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97338
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nicotinic acetylcholine receptor signaling pathway	PANTHER Pathways	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857805
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7418
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72321
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0644
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81723
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15762
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40446
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34171
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71621
Exostosis Of External Ear Canal	DisGeNET Gene-Disease Associations	1.0	null
achr	GeneRIF Biological Term Annotations	1.0	null
hypertelorism	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4392
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.44256
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neonatal myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79661
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5203
PMC3882710__F8	PFOCR Pathway Figure Associations 2024	1.0	null
muscle contraction	GO Biological Process Annotations 2025	1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35066
neck pterygia	HPO Gene-Disease Associations	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45559
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
Navicular bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
channel activity	GO Molecular Function Annotations 2025	1.0	null
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22943
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32497
CRCGN014_HEPG2_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13873
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28545
abnormality of placental membranes	HPO Gene-Disease Associations	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.850181
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.321685
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.14574
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27169
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.402
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00025
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23699
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73348
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56086519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25247
neonatal respiratory distress	HPO Gene-Disease Associations	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurotransmitter-gated ion-channel transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66977
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69326
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48561
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06791
inactivation	GeneRIF Biological Term Annotations	1.0	null
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76771
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59612
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.38656
no spontaneous movement	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K47538257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64011
BRD-K25688236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03838
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19868
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16607
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97404
BRD-K16079077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3304
abnormality of phalangeal joints of the hand	HPO Gene-Disease Associations	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828183
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
axillary pterygia	HPO Gene-Disease Associations	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
fenspiride-1422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34817
BRD-K24639784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31252
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28258
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
paralysis	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.67243
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
contractures involving the joints of the feet	HPO Gene-Disease Associations	1.0	null
BRD-K54476947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22298
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
Multiple Pterygium Syndrome, Lethal Type	DisGeNET Gene-Disease Associations	1.0	null
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
BRD-K71944937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17544
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.70621
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27201
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63449
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06256
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054836
Arthrogryposis multiplex congenita-5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14193
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15807
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.01852
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dysmorphic Facies	DisGeNET Gene-Phenotype Associations	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.62684
abnormality of the aorta	HPO Gene-Disease Associations	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22814
prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
BRD-K35304243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12908
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53533
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34837
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874535
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34903
CGTH-W-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05124
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.34111
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paramyotonia congenita of Von Eulenburg	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Electrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0631
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74091626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10156
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08256
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881575
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5802
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931014
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.155582
Congenital disorder of glycosylation Ij	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05162
RPS6KA3	Hub Proteins Protein-Protein Interactions	1.0	null
skeletal muscle atrophy	HPO Gene-Disease Associations	1.0	null
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.59948
BRD-K74823182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24243
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
Superior colliculus, motor related, deep white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07759
HS274T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79534
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3294
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97769
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38943
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862381
BRD-K75534737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35608
Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell	Reactome Pathways 2014	1.0	null
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
Nemaline myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05066
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2162
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62315
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36274
abnormal muscle fiber morphology	MPO Gene-Phenotype Associations	1.0	null
PMC8238961-41467_2021_23899_MOESM5_ESM.xlsx-TG_MODEL3_AA-UCSC_RefGene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30772101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07831
dehydration	MGI Mouse Phenotype Associations 2023	1.0	null
GLC82	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59852
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5422
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49862
Perturb_2370_KD_PRPF8_ERP116477	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.69502
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57919
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81527
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902328
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMG complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5498
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Spina Bifida	DisGeNET Gene-Disease Associations	1.0	null
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Diaphragmatic eventration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8891
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.26669
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23767
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19072
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44952
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A24436948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6888
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	2.23975
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958418
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225267
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989756
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56869
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
Inflammation	CTD Gene-Disease Associations	1.0	1.3228
Spina bifida occulta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99015
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
Larsen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33013
SW1417	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04524
NCIH322	CCLE Cell Line Gene Expression Profiles	1.0	1.42479
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061489
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35531
NB10	DepMap CRISPR Gene Dependency	1.0	2.444
CRCGN016_MCF10A.TP53.M_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2805
CAOV4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14696
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
difference	GeneRIF Biological Term Annotations	1.0	null
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12832
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072848
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26293
acetylcholine	GeneRIF Biological Term Annotations	1.0	null
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65854
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71858
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5581
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845208
Moebius syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.563005
phenazopyridine-5758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00018
20145155-Table2	GeneSigDB Published Gene Signatures	1.0	null
PIPECURONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.756171
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10008
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860903
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26403
Aplasia Of Muscle	DisGeNET Gene-Disease Associations	1.0	null
BRD-K94277689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88656
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58902
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82779
BRD-K58323923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43899
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12141
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71159
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09078
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02167
pseudopseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.942443
alfaxalone-6514	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.531154
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28083
families	GeneRIF Biological Term Annotations	1.0	null
abnormality of the synovia	HPO Gene-Disease Associations	1.0	null
BRD-K46936109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10234
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
abnormal synapse morphology	MPO Gene-Phenotype Associations	1.0	null
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58067
Plasma membrane signaling receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0656
SP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1273
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.443347
TET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37345
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887077
abnormality of the rib cage	HPO Gene-Disease Associations	1.0	null
abnormality of the radius	HPO Gene-Disease Associations	1.0	null
ceftazidime-5054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16169
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.2477
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31529
BRD-K47800849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55052
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11508
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5330-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54713
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.08578
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
suggests	GeneRIF Biological Term Annotations	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074147
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.64361
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal motor neuron morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23767
all	GWASdb SNP-Phenotype Associations	1.0	0.0353
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69322
chr2_232537797_C_T_b38	GTEx eQTL 2025	1.0	5.43862
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34114
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
rocker bottom foot	HPO Gene-Disease Associations	1.0	null
Camptodactyly Of Toe	DisGeNET Gene-Disease Associations	1.0	null
Oligohydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984386
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1686
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06341
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80461
joint contracture of the hand	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24465
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27672
sirolimus-6967	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Slow muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
PMC12540438-Data_Sheet_1.PDF-20-ZNF527_ZNF527	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911883
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33916
BRD-K36468214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55677
narrow mouth	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30625
hypospadias	HPO Gene-Disease Associations	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056719
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93514
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Emery-Dreifuss muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855603
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
metamizole sodium-4310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_324_KD_BCAP31_SRP320890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.26945
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
increased susceptibility to fractures	HPO Gene-Disease Associations	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.274
transmitter-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47421
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67878
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95067
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87076
Respiratory Distress Syndrome, Newborn	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14629
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16885
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
polyhydramnios	HPO Gene-Disease Associations	1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
fusion	GeneRIF Biological Term Annotations	1.0	null
did	GeneRIF Biological Term Annotations	1.0	null
BRD-K05096562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3175
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24387065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0444
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856217
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69238
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15551
BRD-K03624299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69666
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24582
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.994067
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.79432
Lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59896
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826225
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72403
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07015
Aplasia/Hypoplasia Of The Abdominal Wall Musculature	DisGeNET Gene-Phenotype Associations	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03293
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.32535
membrane part	GO Cellular Component Annotations 2015	1.0	null
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55599
Neurotransmitter-gated ion-channel, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
acetylcholine-gated monoatomic cation-selective channel activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K69482343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1278
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8333
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97553
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09432
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63312
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89496
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7084
Nemaline myopathy 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
anterograde trans-synaptic signaling	GO Biological Process Annotations 2023	1.0	null
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72501
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962171
adrenosterone-6486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06217
BRD-K47014407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05657
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal embryonic growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-A24524033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22911
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09793
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
Puberty, Precocious	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K78712486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37709
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33498
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16429
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9387
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25121
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76835
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053573
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054714
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2607
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13784
bff3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61724
abnormality of the elbow	HPO Gene-Disease Associations	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
myod1	GeneRIF Biological Term Annotations	1.0	null
Leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.855
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58311
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE169571_3_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.70573
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.8375
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42669
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78786
NUGC3	DepMap CRISPR Gene Dependency	1.0	2.3314
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67979
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93828
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00991
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5305-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9112
Neurotransmitter-gated ion-channel	InterPro Predicted Protein Domain Annotations	1.0	null
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32501
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.016
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
single organism signaling	GO Biological Process Annotations 2015	1.0	null
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
trait	GeneRIF Biological Term Annotations	1.0	null
abnormality of the sternum	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal spinal cord grey matter morphology	MPO Gene-Phenotype Associations	1.0	null
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23736
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
RAPACURONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.756171
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NL-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27792
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69339
trunk curl	MGI Mouse Phenotype Associations 2023	1.0	null
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43999
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62909
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.506
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Congenital myopathy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3065
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
abnormality of the scalp hair	HPO Gene-Disease Associations	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77352
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1652
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
time	GeneRIF Biological Term Annotations	1.0	null
baf8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	1.20376
Brain Lower Grade Glioma_LGG_TCGA-P5-A780-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37372
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35739
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1583
BRD-K20199304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04635
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88699
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	2.02915
pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.49819
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5448
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
KYSE30	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19915
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05821
proteolysis	Phosphosite Textmining Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89624
BRD-K40610042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02873
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18956
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13834
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7372
talipes equinovarus	HPO Gene-Disease Associations	1.0	null
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93463
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44092
abnormality of muscle morphology	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4633
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13192
depressed nasal ridge	HPO Gene-Disease Associations	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
congenital diaphragmatic hernia	HPO Gene-Disease Associations	1.0	null
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35527
Orbital Separation Excessive	DisGeNET Gene-Phenotype Associations	1.0	null
abnormality of the hairline	HPO Gene-Disease Associations	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38727
muscle fibre	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14896
Centronuclear myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.13433
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88346
ONDA9	DepMap CRISPR Gene Dependency	1.0	3.41661
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21811
abnormal motor neuron innervation pattern	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14731
acetylcholine-gated channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85176
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56019
BRD-K60202553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04294
acetylcholine receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08141
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867934
aplasia/hypoplasia of the skin	HPO Gene-Disease Associations	1.0	null
Acetylcholine	CTD Gene-Chemical Interactions	1.0	null
Congenital Clubfoot	DisGeNET Gene-Disease Associations	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05418
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81804
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28535
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840549
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2949_KD_Msi2_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
no spontaneous movement	MPO Gene-Phenotype Associations	1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19639
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.612229
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Intercrural Pterygium	DisGeNET Gene-Phenotype Associations	1.0	null
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66484
BRD-K13383838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41513
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06281
TCF3	ENCODE Transcription Factor Targets	1.0	null
Kyphosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
REH	GDSC Cell Line Gene Expression Profiles	1.0	1.62615
proton-transporting ATP synthase complex, coupling factor F(o)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14815
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71471
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18829
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MC-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15454
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45585
disease	GWASdb SNP-Disease Associations	1.0	0.033239
BRD-K51131084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6767
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29705
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31336
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76357
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050267
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pterygium	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.801
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.589
hsa-miR-3978	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1417
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12924
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37452
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48077
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050399
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
syndromes	GeneRIF Biological Term Annotations	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
hsa-miR-3127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29126
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42148
all	HPO Gene-Disease Associations	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Abnormality Of The Tongue	DisGeNET Gene-Phenotype Associations	1.0	null
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93495
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17851
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
hernia	HPO Gene-Disease Associations	1.0	null
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91677
proadifen-7165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
BRD-K98008739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01797
quipazine-2782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nemaline myopathy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52894
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14332
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Amyotrophic Lateral Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15437
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836116
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08558
Z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
RFXANK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37208
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.588431
prenatal movement abnormality	HPO Gene-Disease Associations	1.0	null
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53146
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52041
chrng	GeneRIF Biological Term Annotations	1.0	null
PMC8238961-41467_2021_23899_MOESM5_ESM.xlsx-TG_MODEL4_AA-UCSC_RefGene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	3.10483
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal spinal nerve morphology	MPO Gene-Phenotype Associations	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84355
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
syndactyly	HPO Gene-Disease Associations	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04177
Perturb_4876_KD_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.9344
BRD-K30310008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11533
Adult pleomorphic rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
abnormality of phalanx of finger	HPO Gene-Disease Associations	1.0	null
other aberrant phenotype	MPO Gene-Phenotype Associations	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
BRD-K55187504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36067
Cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
BRD-K38966099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02743
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5582
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
Transmembrane actin-associated (TAN) line	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86353
Congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60632
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14137
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72188
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052497
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34737
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81468
meptazinol-4188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30735
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.1892
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27456
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.605688
BRD-K18888894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27738
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PARP2_KD_GSE43981_676_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41797
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal diaphragm morphology	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18859
Myotonia congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
Spondylocarpotarsal synostosis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09329
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10798
abnormality of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24729
BRD-A17658676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44122
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.975482
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
C4II	DepMap CRISPR Gene Dependency	1.0	3.18423
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42239
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4398
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.847
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.41087
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83012560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75061
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55466
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30456
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88737
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5807
abnormality of the abdominal musculature	HPO Gene-Disease Associations	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8817
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18182
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56451
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853788
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39188
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48401
SMC3	ENCODE Transcription Factor Targets	1.0	null
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
PLBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6722
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99225
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
synostosis of joints	HPO Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33388
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31673
GALLAMINE TRIETHIODIDE	DGIdb Drug Targets 2026	1.0	0.343714
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94657
Hypertension	CTD Gene-Disease Associations	1.0	1.06116
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
32p-labeled	Phosphosite Textmining Biological Term Annotations	1.0	null
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01286
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG63	DepMap CRISPR Gene Dependency	1.0	2.06221
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49412
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05363
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.739488
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11396
excitatory extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26047
Muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82214
biological_process	GO Biological Process Annotations 2015	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Vertical Talus	DisGeNET Gene-Disease Associations	1.0	null
edman	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K16663346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21784
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.37555
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11418
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80829
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29794
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-9	GDSC Cell Line Gene Expression Profiles	1.0	1.59949
Longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08546
abnormality of lower limb joint	HPO Gene-Disease Associations	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6576
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44202
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58703
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02478
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00694
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898832
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Muscle-slow muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.385251
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07759
RD	CCLE Cell Line Gene Expression Profiles	1.0	1.41347
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36153
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11712
BRD-K76537832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25719
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13984
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04725
excitatory extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2023	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9831
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55155
congenital contracture	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arthrogryposis-like hand anomaly	ClinVar Gene-Phenotype Associations 2025	1.0	null
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
Developmental delay and seizures with or without movement abnormalities	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5443
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18763
BRD-K31812476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39887
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60325
cell junction	GO Cellular Component Annotations 2015	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital structural myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5026
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20811
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4514
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6849
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.73
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42932
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.39233
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.17616
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67096
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997767
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21563
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.22
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06363
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50128
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47788
abnormality of toe	HPO Gene-Disease Associations	1.0	null
ATRACURIUM BESYLATE	DGIdb Drug Targets 2026	1.0	0.630143
growth delay	HPO Gene-Disease Associations	1.0	null
diminished movement	HPO Gene-Disease Associations	1.0	null
abnormal hair pattern	HPO Gene-Disease Associations	1.0	null
abnormality of the vasculature	HPO Gene-Disease Associations	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Muscle-fast muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.385251
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15865
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83334
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929958
Lambert-Eaton myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04108
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.36063
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01785
Brain Lower Grade Glioma_LGG_TCGA-TM-A84F-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.7906
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the vertebrae	HPO Gene-Disease Associations	1.0	null
KRAS.KIDNEY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61554
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.87548
20203266-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18715
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44351
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40242
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
abnormal innervation	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054564
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884742
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.73219
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
G402	CCLE Cell Line Gene CNV Profiles	1.0	1.50548
RIDDLE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54013
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia/hypoplasia of the abdominal wall musculature	HPO Gene-Disease Associations	1.0	null
intermediate stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01736
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08372
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04061
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.42965
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Abnormality Of Aortic Valve	DisGeNET Gene-Disease Associations	1.0	null
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73934
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.896748
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42581
short digit	HPO Gene-Disease Associations	1.0	null
bilateral camptodactyly	HPO Gene-Disease Associations	1.0	null
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15266
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39115
achrgamma	GeneRIF Biological Term Annotations	1.0	null
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
Bone Diseases, Developmental	CTD Gene-Disease Associations	1.0	2.88009
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17502
BRD-K30013099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73772
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Type 1 diabetes mellitus_Muscle - Striated (Skeletal) (MMHCC)_GSE1659	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.36913
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92144
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057096
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64276
Flexion Contracture	DisGeNET Gene-Disease Associations	1.0	null
ZNF316	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23651
neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.13165
congenital myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2356
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
neoplasm	HPO Gene-Disease Associations	1.0	null
increased variability of skeletal muscle fiber size	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K90149465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27681
Thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
abnormality of the head	HPO Gene-Disease Associations	1.0	null
abnormal suckling behavior	MPO Gene-Phenotype Associations	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
nemaline myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.745985
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the humeroradial joint	HPO Gene-Disease Associations	1.0	null
Perturb_524_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.97284
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1312
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Congenital ptosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7223
caused	GeneRIF Biological Term Annotations	1.0	null
abnormal heart morphology	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52837
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64804596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38921
ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042569
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.003
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
BRD-K14970242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18556
SW620	BioGPS Cell Line Gene Expression Profiles	1.0	0.891308
abnormality of connective tissue	HPO Gene-Disease Associations	1.0	null
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88834
downslanted palpebral fissures	HPO Gene-Disease Associations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65916
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09955
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52147
abnormal prenatal body size	MPO Gene-Phenotype Associations	1.0	null
BRD-K55642725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21903
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36139
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9831
sensitive	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64697
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9412
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01565
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06009
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78045
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25609
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930144
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76349
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47683
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36045
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.8942
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02295
antecubital pterygium	HPO Gene-Disease Associations	1.0	null
BRD-K40837535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19904
multiple pterygia	HPO Gene-Disease Associations	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8996
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984386
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2025	1.0	null
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91722
four	GeneRIF Biological Term Annotations	1.0	null
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64911
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5032
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25054
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12712
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042816
MEGF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74536
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28024
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
escobar syndrome	OMIM Gene-Disease Associations	1.0	null
CAL148	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48202
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74746
SLR24	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03176
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32714
BRD-K50832163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0039
niflumic acid-5071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91377
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43375
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21811
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17952
Fatty Liver	CTD Gene-Disease Associations	1.0	1.30819
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.1486
hsa-miR-1266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Congenital Exomphalos	DisGeNET Gene-Disease Associations	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00368
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31112
SNU387	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48004
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.41665
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4727
abnormal innervation pattern to muscle	MPO Gene-Phenotype Associations	1.0	null
Puberty, Delayed	HuGE Navigator Gene-Phenotype Associations	1.0	null
nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33046
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915095
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03524
GSE86021_0_v_3_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77766
BRD-K57667228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09345
Hypospadias	DisGeNET Gene-Disease Associations	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0511
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33068
placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.306672
Forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
abnormality of the chin	HPO Gene-Disease Associations	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16774
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194548
BRD-K38904629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45015
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06972
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26189
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.987541
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.789
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865577
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.91
characterized	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25131
Myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01253
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3868
hsa-miR-3944-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071298
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12347
Postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16158586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23291
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84564
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0803
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17795
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86643
cystic lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.44386
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73589
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3879
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08708
patellar aplasia	HPO Gene-Disease Associations	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98957
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01759
Hereditary nonpolyposis colorectal cancer type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72647
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60389
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115281
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31781
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82304
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76081
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14619
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12068
BRD-K15615178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25387
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884218
TET1	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A6YH-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62391
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32899
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41875112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02859
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.477
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
Myasthenic Syndromes, Congenital	CTD Gene-Disease Associations	1.0	2.88009
DDR1_knockdown_169_GSE39207	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.41882
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85134
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.43885
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933427
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31011
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
limb joint contracture	HPO Gene-Disease Associations	1.0	null
Symphalangism Affecting The Phalanges Of The Hand	DisGeNET Gene-Disease Associations	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal dermatoglyphics	HPO Gene-Disease Associations	1.0	null
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
congenital structural myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.625319
cryptorchidism	HPO Gene-Disease Associations	1.0	null
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31537
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
functional respiratory abnormality	HPO Gene-Disease Associations	1.0	null
VECURONIUM BROMIDE	DGIdb Drug Targets 2026	1.0	0.630143
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39516
slanting of the palpebral fissure	HPO Gene-Disease Associations	1.0	null
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.30499
abnormality of globe location	HPO Gene-Disease Associations	1.0	null
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13804
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58979
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68394
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54206
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02049
Laryngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71362
MYOD1	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
strabismus	HPO Gene-Disease Associations	1.0	null
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.28963
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49728
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060705
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_6130_KO_Sesn1/Sesn2_SRP294204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.4906
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81181894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06582
MYOG	ENCODE Transcription Factor Targets	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044152
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
muscle system process	GO Biological Process Annotations 2015	1.0	null
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
amyoplasia	HPO Gene-Disease Associations	1.0	null
Neck Pterygia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K92770212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02357
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2718
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06363
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
acetylcholine-activated cation-selective channel activity	GO Molecular Function Annotations 2015	1.0	null
Autosomal recessive multiple pterygium syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49467
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8798
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2691
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.647743
postsynaptic neurotransmitter receptor activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12054
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86846
abnormal skin coloration	MPO Gene-Phenotype Associations	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171036
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18343
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7565
PMC5094973-oncotarget-07-35932-s004.xlsx-c2_cp_biocarta_v4_0_symbols-RELA_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49209
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50221
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
mode of inheritance	HPO Gene-Disease Associations	1.0	null
KNS42	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71836
Presynaptic nicotinic acetylcholine receptors	Reactome Pathways 2024	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9295
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897092
DOXACURIUM	DGIdb Drug Targets 2026	1.0	0.540122
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9783
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03719
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.82021
lethal	GeneRIF Biological Term Annotations	1.0	null
abnormality of the breast	HPO Gene-Disease Associations	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47688
akinesia	HPO Gene-Disease Associations	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.0757
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.26736
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4391
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01471
SG231	DepMap CRISPR Gene Dependency	1.0	3.0042
abnormality of the auditory canal	HPO Gene-Disease Associations	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2125
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59421
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
hearing impairment	HPO Gene-Disease Associations	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synapse part	GO Cellular Component Annotations 2015	1.0	null
Arthrogryposis	DisGeNET Gene-Disease Associations	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65323
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88466
BRD-K64119425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20267
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77726
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.06927
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K07009788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72106
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3044
scoliosis	HPO Gene-Disease Associations	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08319
BRD-K47947160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00811
decreased embryo size	MGI Mouse Phenotype Associations 2023	1.0	null
SAOS2	BioGPS Cell Line Gene Expression Profiles	1.0	1.05502
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26163290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06289
abnormal neurite morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
BRD-K38084509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35173
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A614-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16568
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	2.50392
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01513
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cognitive impairment	HPO Gene-Disease Associations	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hypoplasia of penis	HPO Gene-Disease Associations	1.0	null
elbow dislocation	HPO Gene-Disease Associations	1.0	null
BRD-K15980298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10003
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphangioma	DisGeNET Gene-Disease Associations	1.0	null
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
Hs-578-T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6542
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27154
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53701
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929081
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83612
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
homosalate-4355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81552
IRS1_KO_GDS1219_303_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0196
abnormal gas homeostasis	MPO Gene-Phenotype Associations	1.0	null
pulmonary hypoplasia	HPO Gene-Disease Associations	1.0	null
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48949
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469211
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956892
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36815
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19063
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
intestinal malrotation	HPO Gene-Disease Associations	1.0	null
abnormality of the urethra	HPO Gene-Disease Associations	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34573
Perturb_6887_KO_PFDN5_SRP273783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.94045
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02123
refractive error	GWASdb SNP-Disease Associations	1.0	1.59609
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874535
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3204
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18988
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1447
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18351
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0846
acetylcholine receptor activity	GO Molecular Function Annotations 2025	1.0	null
Myofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33111
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74235
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056975
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43213
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88494268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33433
abnormal posture	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864298
Myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.994885
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58959
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36436
Neuromuscular junction of somatic muscle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.947
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01205
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24582
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
pg4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36168
Perturb_8751_KD_BRCA2_SRP125262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28696
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.752991
vertebral segmentation defect	HPO Gene-Disease Associations	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18432
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54736
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71208
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.65417
abnormality of the neck	HPO Gene-Disease Associations	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09825
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34182
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73351
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5833
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825425
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66843
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27694
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00212
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.004109
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59799
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830435
Clubfoot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
MYOG_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal tendon morphology	HPO Gene-Disease Associations	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2956
short stature	HPO Gene-Disease Associations	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4695
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35912
BRD-K27600134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19885
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.474119
Weight Loss	CTD Gene-Disease Associations	1.0	1.18359
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66922
cleft palate	HPO Gene-Disease Associations	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6446
Myasthenias	DisGeNET Gene-Disease Associations	1.0	null
Thin Rib	DisGeNET Gene-Phenotype Associations	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87733
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11519
Nicotinic acetylcholine receptor	InterPro Predicted Protein Domain Annotations	1.0	null
clear	GeneRIF Biological Term Annotations	1.0	null
Perturb_10644_KO_Gclc_SRP321080	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.6618
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22013
side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140865
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33584
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7014
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91171
clubfoot	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.920498
gamma	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4518	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
pneumonia	GWASdb SNP-Disease Associations	1.0	0.443424
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1894
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41197
Necrosis	CTD Gene-Disease Associations	1.0	1.25463
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46492
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of muscle size	HPO Gene-Disease Associations	1.0	null
hypoplastic heart	HPO Gene-Disease Associations	1.0	null
EM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.956043
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03049
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_62_KD_Ccnt2_SRP312148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.04132
increased motor neuron number	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06066
chinese	GeneRIF Biological Term Annotations	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864344
Congenital myopathy 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.06003
PMC10795826-jciinsight-8-170518-s128.xlsx-Fig_5B-Gene_Regulated_by_VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26863838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34812
SNU1544	DepMap CRISPR Gene Dependency	1.0	2.5437
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.296972
MYOD1_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cycloplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
BRD-K47814830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24802
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
CHD2_02_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.52356
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27373
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormal skeletal muscle fiber morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.855
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
BRD-K37237818	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0712
abnormality of the vertebral column	HPO Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the knees	HPO Gene-Disease Associations	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.15443
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043388
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
Neonatal Respiratory Distress	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0648
pterygium	HPO Gene-Disease Associations	1.0	null
microcephaly	HPO Gene-Disease Associations	1.0	null
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61012
BRD-K71169857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4665
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71571
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20017
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
PCSK9-LDLR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68416
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95296
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411251
MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	CTD Gene-Disease Associations	1.0	2.88009
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.386308
22RV1	DepMap CRISPR Gene Dependency	1.0	2.00904
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01546
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.38043
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	160.412
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.1511
Transmission across Chemical Synapses	Reactome Pathways 2014	1.0	null
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80017
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.607
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K41707029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09762
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
APCDD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0901
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
variation	GeneRIF Biological Term Annotations	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Fused Cervical Vertebrae	DisGeNET Gene-Disease Associations	1.0	null
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02447
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
more	GeneRIF Biological Term Annotations	1.0	null
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
aplasia/hypoplasia involving bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6051
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38514
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15815
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
particularly	GeneRIF Biological Term Annotations	1.0	null
Flexion Contracture Of Proximal Interphalangeal Joint	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89701
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75206
Perturb_2322_KD_RBMX_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6957
flexion contracture of toe	HPO Gene-Disease Associations	1.0	null
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9479
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
SRY	ChEA Transcription Factor Targets	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
TALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.60376
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.34581
monoatomic ion channel complex	GO Cellular Component Annotations 2025	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81249
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49689
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873775
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85367
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046435
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0922
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66666
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04177
HINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78723
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59907
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K11696795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12298
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59997
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65232
dysplastic patella	HPO Gene-Disease Associations	1.0	null
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.16967
Cardiac Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13944
abnormal motor neuron morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05163
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.29327
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21145
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35764
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.433
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75204
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aconitine-2776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4758-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35285
Pterygium, Antecubital	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11413
lomefloxacin-3620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92773
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03091
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.17864
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
abnormality of upper limb joint	HPO Gene-Disease Associations	1.0	null
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.51188
multiple	GeneRIF Biological Term Annotations	1.0	null
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01546
genetic	GeneRIF Biological Term Annotations	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
downturned corners of mouth	HPO Gene-Disease Associations	1.0	null
Bronchopulmonary dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27188
K029AX	DepMap CRISPR Gene Dependency	1.0	2.23081
BRD-K74591286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2748
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053175
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35889
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10944
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.14747
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060073
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.32926
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061382
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.35313
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-Genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intrauterine growth retardation	HPO Gene-Disease Associations	1.0	null
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889653
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.5977
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24311
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of mouth size	HPO Gene-Disease Associations	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
BRD-K57972271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65369
CISATRACURIUM BESYLATE	DGIdb Drug Targets 2026	1.0	0.472607
USP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59588
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17918
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86861
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08186
pigmentation phenotype	MPO Gene-Phenotype Associations	1.0	null
Acetylcholine binding and downstream events	Reactome Pathways 2024	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
TGFB_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
valproic acid-5574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the calvaria	HPO Gene-Disease Associations	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2947_KD_Ddx17_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0459
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
thin diaphragm muscle	MPO Gene-Phenotype Associations	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82625
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03452
abnormality of pelvic girdle bone morphology	HPO Gene-Disease Associations	1.0	null
Atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
Extensor digitorum communis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0762
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06828
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09716
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
Low Set Ears	DisGeNET Gene-Disease Associations	1.0	null
Pterygium	DisGeNET Gene-Disease Associations	1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.21402
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27048
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22052
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4432	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980911
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43344
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0234
Hypertrophy	CTD Gene-Disease Associations	1.0	1.05274
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
chrna1	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.744729
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05001
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5603
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33668
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.864
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77982
AM38	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05307
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01418
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19621
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051605
Synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.353
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87827
RD	CCLE Cell Line Gene CNV Profiles	1.0	2.04223
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01685
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2245
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33317
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06148
distal arthrogryposis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31974
BRD-K30105551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3638
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.929938
abnormality of digit	HPO Gene-Disease Associations	1.0	null
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.104
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61858
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9847
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
foliosidine-3636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC3882710__F8	PFOCR Pathway Figure Associations 2023	1.0	null
congenital abnormal hair pattern	HPO Gene-Disease Associations	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10814
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57176
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12513
PMC5054603__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0602
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837255
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00804
congenital	GeneRIF Biological Term Annotations	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.011
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
YD38	CCLE Cell Line Gene Expression Profiles	1.0	1.6967
Aplasia/Hypoplasia Of The Skin	DisGeNET Gene-Phenotype Associations	1.0	null
NCIH1618	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14885
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FD-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53496
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09402
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
indian	GeneRIF Biological Term Annotations	1.0	null
abnormal phrenic nerve innervation pattern	MPO Gene-Phenotype Associations	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Short Finger	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13175
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90594
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4972
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
SIN3A	ENCODE Transcription Factor Targets	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43137
Arthrogryposis multiplex congenita	ClinVar Gene-Phenotype Associations 2025	1.0	null
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62581
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
systolic	GeneRIF Biological Term Annotations	1.0	null
abnormality of the female genitalia	HPO Gene-Disease Associations	1.0	null
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30286
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930144
fibro-adipogenic progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17994
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63836
upslanted palpebral fissure	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80972048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20552
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17451
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948449
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
17210682-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94477
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61775
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15402
Abnormal Cervical Curvature	DisGeNET Gene-Phenotype Associations	1.0	null
diaphragmatic eventration	HPO Gene-Disease Associations	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
thymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.355235
BRD-K40117723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01473
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
long philtrum	HPO Gene-Disease Associations	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67061
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867636
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MERO41	DepMap CRISPR Gene Dependency	1.0	2.47947
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2074
aplasia/hypoplasia involving the skeletal musculature	HPO Gene-Disease Associations	1.0	null
NEUROD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42524
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13728
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29944
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32131
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
symphalangism affecting the phalanges of the hand	HPO Gene-Disease Associations	1.0	null
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04074
OELE	CCLE Cell Line Gene Expression Profiles	1.0	2.16823
ATXN7L3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.5347
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
Neck Webbing	DisGeNET Gene-Disease Associations	1.0	null
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149753
low-set ears	HPO Gene-Disease Associations	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.15967
diphenylpyraline-3640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.405678
cellular response to acetylcholine	GO Biological Process Annotations 2025	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.698
telecanthus	HPO Gene-Disease Associations	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70512
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24341
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14546
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0361
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2323
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.33376
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23056
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05518
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58075
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754002
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44556
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27705
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16774
TTC709	DepMap CRISPR Gene Dependency	1.0	2.51711
BRD-K83316435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33094
chloropyrazine-6148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17172
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.34313
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
neoplasm of the skeletal system	HPO Gene-Disease Associations	1.0	null
LN382	CCLE Cell Line Gene Expression Profiles	1.0	1.49355
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2235
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K76985713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00874
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1111
HCC2935	DepMap CRISPR Gene Dependency	1.0	4.12888
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9044
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84845
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39266
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00196
Flexor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24995
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911043
BRD-K25234731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60693
mcf7	HPA Cell Line Gene Expression Profiles	1.0	0.858412
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84568
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955629
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30055322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32774
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24224
TC32	CCLE Cell Line Gene Expression Profiles	1.0	3.2329
Skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20176
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042996
BRD-K32522654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50852
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Postsynaptic nicotinic acetylcholine receptors	Reactome Pathways 2014	1.0	null
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07485
GCIY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5461
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86494
minocycline-5077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN013_HEPG2_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43809
MCC26	DepMap CRISPR Gene Dependency	1.0	3.60477
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35152
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1448
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.113447
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64271
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836378
lower extremity joint dislocation	HPO Gene-Disease Associations	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85741
ICC2	DepMap CRISPR Gene Dependency	1.0	3.46189
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
heterotrimeric g-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.297342
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65829
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Myasthenic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90694
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23882
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.70632
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32168
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
GSE173201_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
complete postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69514
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the tarsal bones	HPO Gene-Disease Associations	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39145
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presynaptic nicotinic acetylcholine receptors	Reactome Pathways 2014	1.0	null
BRD-K31883641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60633
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053715
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59284
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.09136
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
arthrogryposis multiplex congenita	HPO Gene-Disease Associations	1.0	null
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
abnormal prenatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	2.20893
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
Arachnodactyly	DisGeNET Gene-Disease Associations	1.0	null
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89299
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16731
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8402
functional abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29257
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Patellar Aplasia	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.67149
BRD-K63211622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03227
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06259
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
guanadrel-2575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23976
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15691
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26172
ARHGEF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46838
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996264
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24925
suxibuzone-6065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
camptodactyly of finger	HPO Gene-Disease Associations	1.0	null
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23767
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
abnormal bone structure	HPO Gene-Disease Associations	1.0	null
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32989
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56861
aplasia involving bones of the extremities	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	2.09529
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984386
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28664
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94565
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31701
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9673
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5128
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
15980968-Table3b	GeneSigDB Published Gene Signatures	1.0	null
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64327
abnormality of the heart valves	HPO Gene-Disease Associations	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01171
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1703
BRD-K13551202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04851
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49073
HT55	DepMap CRISPR Gene Dependency	1.0	3.65799
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.137694
NCIH211	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47751
HCC364	CCLE Cell Line Gene Expression Profiles	1.0	1.79358
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11746
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
denatonium benzoate-5061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00185
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041187
escobar	GeneRIF Biological Term Annotations	1.0	null
abnormal joint morphology	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia of the cerebellum	HPO Gene-Disease Associations	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
overexpressed	GeneRIF Biological Term Annotations	1.0	null
santonin-4353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17549
LOUNH91	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73858
cell communication	GO Biological Process Annotations 2015	1.0	null
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80027
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00194
Brain Lower Grade Glioma_LGG_TCGA-DU-5849-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFKL_OE_GDS1079_201_mouse_myoblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887221
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27201
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58316
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Fusion Of Ribs	DisGeNET Gene-Disease Associations	1.0	null
TRAF2-GSTP1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7764
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
BRD-K02576169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90333
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17763
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991784
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
cephalothin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21124
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05527
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08764
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02957
abnormal muscle morphology	MPO Gene-Phenotype Associations	1.0	null
Edwards syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09825
BRD-K40432489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4885
Perturb_338_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.57876
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98955
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dysmorphic Features	DisGeNET Gene-Disease Associations	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72042
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2258
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
camptodactyly	HPO Gene-Disease Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7374
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04442
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61197
long clavicles	HPO Gene-Disease Associations	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830691
abnormal endplate potential	MPO Gene-Phenotype Associations	1.0	null
BRD-K82517280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32009
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01703
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.26585