association	dataset	threshold value	standardized value
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38949
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13599
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2657
BAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8562
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70376
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216326_2_v_1_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10751
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4699
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1304
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7077
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65925
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
GSE244072_4_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6156
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
CEP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3661
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76733
IDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52126
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3584
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0963
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
GSE138815,GSE138817_3_v_1_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4706
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40401
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9367
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6397
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.375
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
GSE179868,GSE180330_1_v_0_ddx21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
GSE180813,GSE180815_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATXN7L3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43175
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2235
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37382
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_5_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7036
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
ZNF316	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23651
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9753
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86556
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28008
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.555
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60832
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99953
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91125
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40169
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8344
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.9323
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.975
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36677
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44264
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73302
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9723
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.334
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17699
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71601
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4183
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51978
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7971
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59844
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06443
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8297
GSE113267_0_v_1_rfx7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99375
CCNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67065
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43215
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20175
SOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13963
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7083
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SSBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9576
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7326
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29187
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02021
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0012
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36244
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6998
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.9107
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46339
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3456
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1282
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14807
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1023
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5189
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
ZNF735	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03014
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
BMAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6874
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160077,GSE160084_2_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43253
GPX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83119
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2288
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.1758
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60691_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.2341
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49422
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85933
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
determination of left/right symmetry	GO Biological Process Annotations 2025	1.0	null
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8118
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
GPR143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07136
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93812
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20986
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4064
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80549
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35807
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.273
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1883
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11978
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62525
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17518
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE194268_2_v_0_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46966
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7809
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52313
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54344
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8321
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2688
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
GSE101527_3_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8316
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0446
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8626
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25907
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61667
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9744
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59414
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0955
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11573
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1641
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
ELOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06848
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
ZNF404	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37638
CDH24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86187
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
PIGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77893
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5197
GSE233679_12_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06019
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3449
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6369
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60056
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.1414
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1143
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42512
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3971
EIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
ZNF610	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44176
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60358
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0443
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27914
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7049
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
GSE172146_2_v_1_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44102
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.15296
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
PCDHB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55891
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9995
TST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67769
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2138
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9863
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5724
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9601
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25097
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87128
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36211
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
CTSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23393
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5925
GSE174735_1_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.301
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14245
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.25
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GSE154246_2_v_3_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618
establishment of left/right asymmetry	GO Biological Process Annotations 2025	1.0	null
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89866
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166054_1_v_0_klf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4686
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8114
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.199
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
PFKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78668
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.2655
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0822
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87542
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70275
SRRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95326
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0262
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0813
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3153
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7794
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86016
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7738
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82785
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74785
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00439
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82207
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9361
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.9922
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4855
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389