association	dataset	threshold value	standardized value
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67712
BRD-K45734531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35187
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29198
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4706
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0801
BRD-K65392908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62861
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8201
CRCGN015_MCF10A_48H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43715
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65601
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9626
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27609
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38065
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9952
BRD-K52361779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01021
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_DN_NR2F1_ind_DN-NR2F1_Ind_DN_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15701
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.3567
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19315
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7817
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1254
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03411
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33102
BRD-K00685640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33856
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35579
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr14_104982000_A_G_b38	GTEx eQTL 2025	1.0	3.32005
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4588
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47327
BRD-K41324679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28984
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40532
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76399
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20066
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14753
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03095
TMEM98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21473
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.55276
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8739
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.322
BRD-K34590335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92373
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60088
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40689
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.717
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333169
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.553
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
AP-1 adaptor complex	GO Cellular Component Annotations 2025	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65882
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0892
Clathrin vesicle coat	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90887068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.255
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40787
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26098
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01819
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4742
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19496
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91406875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07664
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.47422
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288691
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22109
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1971
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07845
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11345
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72322
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38545
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04182
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6691
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20095
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.806
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17651
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Downregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.638
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75136523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36582
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46378
RAD51C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.295
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68582
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225447_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38363
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6649
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.7788
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99989
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.78735
BRD-K53665750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60772
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283432
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55413
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34872
BRD-K40432489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14945
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39447
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48773
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85553
BRD-K85059356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39153
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50596260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53425
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88809
BRD-K08433493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20308
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34259
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15801
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32548
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0644
BRD-K24585433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20679
BRD-K48689133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04536
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251145
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44457
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5187
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46163
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5457
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1847
KIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06884
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21765
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03592
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44556
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30503
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00343
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08507
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09397
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296755
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30222
CRCGN010_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21636
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0548
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42776
BRD-K00557942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02288
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.44091
BRD-K21635957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08857
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2448
BRD-K83254798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19992
BRD-K93310782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43759
CRCGN014_HEPG2_3H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09342
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15423
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.82819
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58006
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73078
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7568
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24731
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14225
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.12775
BRD-K92581247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09979
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398239
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1157
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03607
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27738
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21587
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68978
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35561
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316144
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33101
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.018
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25147028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29483
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04089
BRD-K79676802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26337
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
BRD-K72533381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29188
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39466
BRD-K59667434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23255
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33711
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08583
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64546
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13843
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07526417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24236
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68731395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07166
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7158
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3648
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27729
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63766
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57576
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32595757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06404
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56978
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68805
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55702
BRD-K79347939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13444
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02418
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06462
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7103
BRD-K63212062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16892
BRD-K66831269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13082
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93195567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26295
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55898
BRD-K19039785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0837
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53485
BRD-K85851814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54629
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0272
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31437957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00596
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23177
clathrin adaptor complex	GO Cellular Component Annotations 2025	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.01416
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01868
PMC10534007-Table_2.xlsx-S2_overlap_MSC_down_B_V-395_common_elements_in_VM-CUB1_MSC_down_and_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
BRD-K88876691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00997
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-314-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00525
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21729
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15302
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30369
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43937
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22244
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09997
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36024
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219885
BRD-K79547691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70957
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02938
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9557
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52871
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33452
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2938
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43606
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18505
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29702
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6841
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25737
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03502
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79795
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263789
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05639
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09064
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8904
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46613
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09343
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4298
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4275
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27183
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76665
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2053
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39503
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87341
CRCGN012_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06065
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08062
BRD-K93697231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1779
BRD-K07665396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02602
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21105
BRD-K02269304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1429
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.611
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07815
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6448
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78692
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A79884839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24224
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.14538
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04824
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66702
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05052
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58792
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05378
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6252
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.92005
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9177
GSE193993_1_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59745
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67609710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03988
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38604123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05256
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23306
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11106
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RETREG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19264
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4638
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33865
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76582
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35685
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06309
CRCGN015_MCF10A.WT.HP_24H:A24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00599
BRD-K35808731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0607
BRD-K30372674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80324
Coated membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45471346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0474
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9772
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93645
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31057
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65427
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33612
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00303
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48522
GSE252857_2_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42355
BRD-K40011635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30741
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10433
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AP-type membrane coat adaptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K20416270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16988
BRD-A98208100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2143
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.11592
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1537
BRD-K32402344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60238
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3233
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92349794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59453
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39037
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41915
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4462
CRCGN012_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1032
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05859
Isolated cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23353
BRD-K26694226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01215
CRCGN017_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26377
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01934
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306065
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.345
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10563
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7408
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05964
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32446
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25645
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97544
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16276
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6694
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88454
BRD-K12034365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59963
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13147
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214466
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29579
BRD-K56802897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.235
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61908
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16599
BRD-K13119652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0066
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.01088
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11264
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3778
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-Golgi network transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.184
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.532
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73414
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25665
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18521
BRD-K99377541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78168
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80796
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05833
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55656
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07014
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31131
BRD-K88200581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.381
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02125
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62945
BRD-K92379545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62916
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12862541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0134
GSE174362_2_v_0_oridonin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06857
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5423
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.076
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03461
PMC7441006-41388_2020_1389_MOESM2_ESM.xlsx-Supplementary_Table_1-Prostate-Specific_MYC_Overexpression_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K48676303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59014
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7526
Membrane coat	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38219
SDHAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36568
BRD-K77101974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27851
GSE171724_1_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66364
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68251
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36481
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01376
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16962
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00447
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70449
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62863
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.62287
Cerebrospinal fluid t-tau levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51098
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5674
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26875
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2553
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49001
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76943
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19282
BRD-K37850190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03688
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36261
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24836
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0348
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79048
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70924576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31952
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5563
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6864
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2377
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73680186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43876
BRD-K13927197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55458
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.934
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1539
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8183
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1619
BRD-K99172965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09051
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
BRD-K55795421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48453
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12963
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25945
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0008
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.02565
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64337
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5156
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57374
clathrin coat of trans-Golgi network vesicle	GO Cellular Component Annotations 2025	1.0	null
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91371
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16183
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9612
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81791
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04033
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6749
BRD-K86070914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62413
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08798
chr14_104982472_A_G_b38	GTEx eQTL 2025	1.0	1.19587
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21221
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63656
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60253
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23271
BRD-K52300725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01302
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4456
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77871
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54807
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70118
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88711
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.23356
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415942
BRD-K59030325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16732
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11626
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32865
BRD-K03713632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23653
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30306
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42639
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06361
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21472066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25814
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39739
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41891
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.96065
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39464795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41462
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79932
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70495
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0309
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_37_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233907
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66367
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9749
BRD-K79329532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.291
BRD-K96449536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18294
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44722555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02997
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15287
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96222
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1199
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15792
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07999
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9361
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219764
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23364
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06506
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01099
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37956
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2214
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29447
CRCGN008_HEPG2_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3205
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02357
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21633
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01412
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88136
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95285
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26363
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04375
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31308
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18368
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0711
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231728
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75979
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32267
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424064
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07573
BRD-K49698948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3177
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.576604
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38315
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54007898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66791
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8183
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40966
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08204
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2938
BRD-K30013099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81355
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210444
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12214
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81688
BRD-K61704278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17138
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1962
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8178
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257731
BRD-K77011363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41266
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.431657
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69012
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr14_104985884_T_TGCGGGGCCCGGGCCCGGGCCCAGGACAC_b38	GTEx eQTL 2025	1.0	1.27658
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.702
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71889
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10534007-Table_3.xlsx-S8_unique_down_MSC_V_2-345_elements_included_exclusively_in_VMCUB1_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85421
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2731
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87201
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04155570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38358
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.589367
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09416
BRD-K06279388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17562
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13463
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3441
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4767
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11559
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56771
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40103182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6255
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341472
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3095
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88785
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97692
BRD-K75416889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59601
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43521
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08339
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93914
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268644
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44045
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22256
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01314
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275662
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02691
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50504
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02455
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37416
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357073
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14599588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14799
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41916
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Clathrin coat	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0867
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05985
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.621
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:H16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07405
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59338
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77608
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.03537
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08938
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86377
GSE171724_1_v_5_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22802
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327477
BRD-K53127464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42231
BRD-K91795767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39824
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
BRD-K95160020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01681
BRD-K42899345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43834
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
AP-1 adaptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K66748326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09477
BRD-K14889526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18906
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51633
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6573
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.66526
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74106
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50721
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8843
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40652
BRD-K25226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08422
BRD-K24512597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4098
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3404
BRD-K93693615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21109
BRD-K26306512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28784
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9386
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.8035
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33185
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63199
BRD-K97445906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75584
BRD-K07400331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0044
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.7434
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54445
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20978
BRD-K18179332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22745
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.95065
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76819
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-85-KE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20605
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05272
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10236
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20705
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.481
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79072801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86537
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10056
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.419844
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05981
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0186
Golgi-associated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32364
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135565
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.192
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Golgi-associated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K46141002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18415
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12294
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28969
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88485
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06198
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41779
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.658644
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75826
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03656
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92633
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76345
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7722
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22142
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5195
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11761
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60032
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06425
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14968
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385517
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.827
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.386
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.373
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.413129
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8109
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44888
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22987
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
trans-Golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K66870022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26117
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01187
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.4467
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337446
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99892
BRD-K27973265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24406
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87208
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363712
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5358
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53492
BRD-K73166462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53249
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.55074
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.851
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65425
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39153737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8617
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.618
BRD-K27236794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19716
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56512
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26321
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04436
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12749
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20243
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292935
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78262424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23965
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08582
BRD-K52054012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02342
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73577
BRD-K35462787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01284
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255402
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.564
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7957
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14359
GSE158834_1_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17218
BRD-K98560805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38311
GSE252857_2_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20866
CRCGN015_HEPG2_48H:I22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14267
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16584
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3508
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23709
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93693
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2958
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21854
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49203
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78439
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26106
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05383
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3391
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4142
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61523
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2159
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.276
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0501
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87378
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0063
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A90969585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.324
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89447678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39947
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33834
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217907
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.74692
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21562
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209124
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81856
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08319
BRD-K88190816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26455
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53501
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20276
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87168
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.337
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7501
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23342
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6483
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ATAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05457
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25101
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7194
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19294
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.18858
hr5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18446
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28522
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0024
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5267
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38622
BRD-K63920153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5425
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37472
Cerebrospinal fluid t-tau levels in normal cognition	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70194
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9908
BRD-K10343715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22971
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62896
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21946
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	214.96
BRD-K89652482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19406
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15805
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-382-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32614
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63084
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4214
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43578
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30621
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7847
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4272
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74207
BRD-K79148949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19059
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88862
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02494
BRD-K18942395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.107
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56987307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77769
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20837
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Appendix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2977
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65195
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7258
BRD-K14121002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13726
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5513
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1379
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39411
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10215
BRD-K89574562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28929
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
CRCGN011_HEPG2_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1579
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18435
GSE146864,GSE146866_2_v_0_fatostatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96021
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13193
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200899
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36303
BRD-K44363090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10212
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04463
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59821372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21679
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17446
Clathrin adaptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23897
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02936
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00908
GSE180982_1_v_0_mlst8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0009
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203042
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22617
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCC 786-O cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.33133
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54638
BRD-K94685203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55821
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.725
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308766
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1789
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
Appendix adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6936
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22229
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29364
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K48407262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10381
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17344
BRD-K73859343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42856
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-MYOD1_MYOD1	Rummagene Transcription Factor Associations 2026	1.0	null
Vesicle coat	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45679
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.20175
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03065
BRD-K24711162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21655
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1474
BRD-K81656074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76337
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47121
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12198892-pi-2025-0101-Supplementary-Material.pdf-46-PREB_PREB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363986
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48422
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00103
BRD-K07011015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45976
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0466
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14566
PMC3377115-emmm0003-0726-SD7.xls-ESR1_Positive_module-SYMBOL_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47678
BRD-K91354770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29278
BRD-K18657361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67889
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16212
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23434564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46191
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.12463
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5409
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24481
BRD-K22661969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15849
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03699
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84769529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21047
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07895
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.74492
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33185
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96074
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08404
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3936
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38240683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65896
Coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0964
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09165
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80754
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.019
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.537102
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57267
SLC25A27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36176
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39002
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35397
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.564
BRD-K14245433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21382
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01282
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18237
BRD-K22002184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31484
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51809
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1255
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70207
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.572703
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42674
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246759
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51429
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62955
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6182
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29169
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230061
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.80952
PMC10534007-Table_3.xlsx-S8_unique_down_MSC_V-345_elements_included_exclusively_in_VMCUB1_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05536
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3125
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54535
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4078
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.95845
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31644
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7835
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390288
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347922
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02094
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324328
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21018
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66491
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5066
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07882
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79152256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41362
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86707
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.52805
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401206
BRD-K47508820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7011
BRD-K64404450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27323
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.318
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13784
BRD-K27354087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0238
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01557
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48137
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10913
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57365604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33455
BRD-K81447429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19372
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35826866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53223
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77962
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59049030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44907
BRD-K02637850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2818
Transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96493283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08616
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27907
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-Golgi network membrane	GO Cellular Component Annotations 2025	1.0	null
CRCGN014_HEPG2_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33787
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8236
BRD-K53783288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23755
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296321
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13204
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10984
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20915
BRD-K66955555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03786
BRD-A81407814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24444
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45243
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46564
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01641
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.167
BRD-K83934572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00629
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8428
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12659
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14252
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02116
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87033
BRD-K92941354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45034
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34302
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56015010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10422
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
BRD-K27458941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97071
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26293
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63624341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16532
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1704
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trans-Golgi network transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33588
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40764
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43089
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16314
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64425
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20607
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36298
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.30935
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51623
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.03675
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9385
BRD-K54351451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09724
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77004
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66425065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66322
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
chr14_104981896_G_C_b38	GTEx eQTL 2025	1.0	5.59742
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59377
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9886
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04263
BRD-K76942055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54276
BRD-K06264262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91932
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236497,GSE236500_1_v_0_pemrametostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5096
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31803
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.751
BRD-K71842353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20107
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71005
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02754
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_DN_AA_DN-AA_DN_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71931
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3205
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32452
BRD-K95417411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65326
Coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K70537701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05901
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26029
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0912
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20075
BRD-K26992703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01862
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.51788
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00556
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.448
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85875
CRCGN016_MCF10A.WT.HP_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2249
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14418
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.777
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.08113
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.561
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05148
BRD-K63809385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55338
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86955
BRD-K34445019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02552
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37265
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7036
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281053
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72097
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41053
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3674
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36627718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70682
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Endometrial adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9604
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09148
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovarian mucinous adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51795
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68083867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71163
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22179
BRD-K16673836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4562
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15932
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.564
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19924
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04537
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7148
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50876
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12119
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8758
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75615
Integrin alpha2-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11625057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20085
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00767