association	dataset	threshold value	standardized value
MDCK-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.09
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K75900642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75517
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41675
BRD-K69274755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21187
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92685
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994497
vascular disease	GWASdb SNP-Disease Associations	1.0	0.149882
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
JHUEM3	CCLE Cell Line Gene Expression Profiles	1.0	1.70173
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10583
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37429
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
BRD-K13049124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00324
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22603
SKLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56904
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43433
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.875533
Cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.623
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
hsa-miR-182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
endogenous	GeneRIF Biological Term Annotations	1.0	null
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03983
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.506
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906634
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
EAST syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06193
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28133
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904593
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111379
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06505
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2743
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03143
Liver Diseases	CTD Gene-Disease Associations	1.0	1.41008
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.99359
Congenital secretory chloride diarrhea 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11202
hsa-miR-4766-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hypertrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415773
heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115167
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
BRD-K52973286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39692
hsa-miR-216a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
filter	GeneRIF Biological Term Annotations	1.0	null
claudins2	GeneRIF Biological Term Annotations	1.0	null
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.663578
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65821
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00133
water	GeneRIF Biological Term Annotations	1.0	null
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36728
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13223
KNS-62	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05228
Primary hypomagnesemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.537
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06266
FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2123
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01214
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057937
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.118529
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978347
BRD-K95895516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61461
hsa-miR-876-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99508
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56363
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96675
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83766
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.327748
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.02349
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34895
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79091
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82805160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34283
BRD-K73479560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35122
FOS	ENCODE Transcription Factor Targets	1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
JUND_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796458
Kidney Failure	DisGeNET Gene-Disease Associations	1.0	null
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86495
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Developmental and epileptic encephalopathy 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182723
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19955
kidney	HPA Tissue Gene Expression Profiles	1.0	1.85323
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052889
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08171
localization	GO Biological Process Annotations 2015	1.0	null
Myopia	DisGeNET Gene-Disease Associations	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.19661
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02639
BRD-K50127933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45207
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898372
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06141
CRCGN015_MCF10A.WT.HP_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18881
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899939
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
apical junction complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
E2F4	ENCODE Transcription Factor Targets	1.0	null
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68257
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00263786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04216
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.365911
BRD-K93486796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70592
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18119
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
MHC class Ib protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
resistance	Phosphosite Textmining Biological Term Annotations	1.0	null
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.32328
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20399
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966038
nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.72361
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.09227
vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159123
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.387714
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08865
BRD-K67016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28891
C-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12307
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89437
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83873
BRD-K71538933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28321
BRD-K34005205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2563
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04472
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87315
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
LAMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25895
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29867
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154288
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84645
intracellular monoatomic ion homeostasis	GO Biological Process Annotations 2023	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A61864215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21803
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853697
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
CRCGN015_MCF10A_48H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43103
Perturb_17446_KD_NOX4_SRP290143	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.39705
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
DEL	DepMap CRISPR Gene Dependency	1.0	2.55683
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.326
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
Lesch-Nyhan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.678
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32482
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89345
BRD-A71666580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13701
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28478
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
magnesium ion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22482
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259109
complete	GeneRIF Biological Term Annotations	1.0	null
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85763
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
HMCES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89816
p107_Deficiency_GDS3176_606_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4772
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.04055
H3118	DepMap CRISPR Gene Dependency	1.0	4.12246
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4231
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85001
BRD-K40685792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34978
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
monoatomic cation transport	GO Biological Process Annotations 2025	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16157
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965277
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
different	GeneRIF Biological Term Annotations	1.0	null
Kenny-Caffey syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
LIPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58598
BRD-K37029442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15243
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7913
Human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
Renal pyramid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
tight junction assembly	GO Biological Process Annotations 2023	1.0	null
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74494
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0512
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.093453
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902989
OVSAHO	CCLE Cell Line Gene Expression Profiles	1.0	1.60355
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155031_5_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33128056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.98395
BRD-K07762528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57091
bleomycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05192
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832857
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877655
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
junctions	Phosphosite Textmining Biological Term Annotations	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42017
Weight Loss	CTD Gene-Disease Associations	1.0	1.10769
tight junction	GO Cellular Component Annotations 2023	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057832
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
maturity-onset diabetes of the young	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
BRD-K37906761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10715
SRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5487
mek	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87625
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2023	1.0	null
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0427
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.642
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
RELA	ChEA Transcription Factor Targets	1.0	null
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.16377
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00786
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9808
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7815
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60732
BRD-K49999779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4927
BRD-K87419143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72854
eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.278654
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834126
PMC10245467-mmc3.pdf-266-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11836325-41467_2025_56634_MOESM8_ESM.xlsx-gene_table_NGS5844-Supplementary_Data_6_Gene_targets_lost_in_resistant_cells_upon_FOSL1_knockdown_and_their_corresponding_hallmark_pathway_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41588
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11577
secretion	GeneRIF Biological Term Annotations	1.0	null
BRD-K68985225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01186
BRD-K31584969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63432
BRD-K65796649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08893
BRD-K91726436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14254
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53538
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58205
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45496
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Cell-cell junction organization	Reactome Pathways 2024	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91895574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13701
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
hsa-miR-4314	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40366
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.825
brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.17984
BRD-K24443173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59528
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.539472
Apicolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29846
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61888
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3037
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
HT144	DepMap CRISPR Gene Dependency	1.0	2.91852
Outer dental epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
cyclase	Phosphosite Textmining Biological Term Annotations	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.025
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tight junction	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19959
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879687
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15389388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35846
Caov-4	GDSC Cell Line Gene Expression Profiles	1.0	1.58824
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
hsa-miR-4677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
EZH2	ENCODE Transcription Factor Targets	1.0	null
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081351
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50569
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03917
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93053
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69566
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01803
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17627
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20931
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74509
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
stx8	GeneRIF Biological Term Annotations	1.0	null
BRD-K76588081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56065
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48933
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51509
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77298
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15688
Factor XI deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051261
BRD-K77023196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12456
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99203
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15211
BRD-K37989903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.956
RCOR1	ENCODE Transcription Factor Targets	1.0	null
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8471
SNU349	DepMap CRISPR Gene Dependency	1.0	6.14698
abnormal renal reabsorption	MGI Mouse Phenotype Associations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896455
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882327
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
Renal hypomagnesemia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
BRD-K09078201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56104
Epithelial to mesenchymal transition in colorectal cancer	WikiPathways Pathways 2024	1.0	null
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6775
occluding junction	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84609
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7735
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.029
BRD-K97733472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82526
CRCGN016_MCF10A.TP53.M_24H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26801
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71668
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00612
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6749
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89614
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K37588779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01189
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47143916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93693
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04704
associations	GeneRIF Biological Term Annotations	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.40568
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09075
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04555
cellular ion homeostasis	GO Biological Process Annotations 2015	1.0	null
BRD-K30284601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41791
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880827
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49145
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0433
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03129
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.35795
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13097
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454126
VMRC-RCW cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
Familial isolated hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19716
clinical	GeneRIF Biological Term Annotations	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.3851
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
BRD-K90769476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52858
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2698
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25544
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17347
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981358
hsa-miR-4749-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
zo1	GeneRIF Biological Term Annotations	1.0	null
ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.156533
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06794
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21151
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
abnormal mineral level	MPO Gene-Phenotype Associations	1.0	null
BRD-K92812209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.378
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98354
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49122
Edema	CTD Gene-Disease Associations	1.0	1.1403
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27829
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96247
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.889646
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64665
BRD-K05221385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55074
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278603
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97397
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91743
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.68523
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
mitogen-activated-protein-kinase-1	Phosphosite Textmining Biological Term Annotations	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03313
EFO21	CCLE Cell Line Gene Expression Profiles	1.0	2.50568
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
BRD-K31390971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34366
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Nephron epithelial cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94079
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858642
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6632
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25858
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4127
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00212
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
form	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84128738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14769
hypocitraturia	HPO Gene-Disease Associations	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940606
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943184
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50918
BRD-K61310138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3982
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00003
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21425
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81451
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29517
hsa-miR-4457	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.087
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8178
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27289
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.512
Tight junction interactions	Reactome Pathways 2024	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045106
FARAGE	DepMap CRISPR Gene Dependency	1.0	4.86765
Hypomagnesemia primary	CTD Gene-Disease Associations	1.0	2.88009
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
NR3C1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
polyuria	HPO Gene-Disease Associations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447576
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50976
GSE168097_0_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28522
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25468
BRD-K96958073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00792
VA-ES-BJ	GDSC Cell Line Gene Expression Profiles	1.0	2.14613
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01083
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41061
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0877
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09944
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81459
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
claudin	GeneRIF Biological Term Annotations	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0946
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Virion - Hepatitis viruses	KEGG Pathways 2026	1.0	null
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
abnormality of nitrogen compound homeostasis	HPO Gene-Disease Associations	1.0	null
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02262
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
Amyloidosis	DisGeNET Gene-Disease Associations	1.0	null
Primary hyperoxaluria type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14878
OVTOKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
endocrine	GeneRIF Biological Term Annotations	1.0	null
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26126
BRD-K65203256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52039
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20178
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.131
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73508
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
BRD-K73872184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05607
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76114475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97819
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83797
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.904393
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49308
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
GM133	BioGPS Cell Line Gene Expression Profiles	1.0	1.15337
Renal Calcium Wasting	DisGeNET Gene-Phenotype Associations	1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
CRCGN009_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06279
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4966
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32218
present	GeneRIF Biological Term Annotations	1.0	null
podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
PMC5572672__F2	PFOCR Pathway Figure Associations 2024	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.913
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tetany	DisGeNET Gene-Disease Associations	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50697
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bartter disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.76425
GSE180468_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46587
KRAS.AMP.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
Nephrogenic diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.778
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.84493
BRD-K11342801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19092
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86169
CHD1	ENCODE Transcription Factor Targets	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-01A-21R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03777
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38196
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.248578
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
riluzole-3666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.516
A388	DepMap CRISPR Gene Dependency	1.0	5.2888
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09428
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83112
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25475
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9306
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3462
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74077
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90887
SRSF4_02_04	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60768
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68958
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74642
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.51556
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13625
BRD-K24977393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24983
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	2.18094
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07356
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77042
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39769
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9976
conductance	GeneRIF Biological Term Annotations	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5719
BRD-K29850806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8985
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.816
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952707
hsa-miR-514	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
kidney	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Liddle syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9223
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K00877314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08542
second	GeneRIF Biological Term Annotations	1.0	null
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11121
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11711
repressor	GeneRIF Biological Term Annotations	1.0	null
Kidney Calculi	DisGeNET Gene-Disease Associations	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898919
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.69419
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98273
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00713
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963967
cellular metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05005
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01745
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04182
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05076
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045531
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71008
PBX3	ENCODE Transcription Factor Targets	1.0	null
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
increased urine calcium level	MPO Gene-Phenotype Associations	1.0	null
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
PMC5356793__F4	PFOCR Pathway Figure Associations 2023	1.0	null
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2023	1.0	null
BRD-K40935524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43566
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841654
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905756
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.941
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K20110031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01869
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Phosphoribosylpyrophosphate synthetase superactivity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59202
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.966407
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0965
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88583132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01323
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03477
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP2	DepMap CRISPR Gene Dependency	1.0	3.61093
family	GeneRIF Biological Term Annotations	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49489
ovarian surface epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.198091
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65951
Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kearns-Sayre syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03897
CBX3	ENCODE Transcription Factor Targets	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K98505253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06046
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1651
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
Perturb_9077_KD_SRSF7_SRP365961	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Renal hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17269
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28593
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.073
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15717
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.42966
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
abnormality of the level of lipoprotein cholesterol	GWASdb SNP-Phenotype Associations	1.0	0.659244
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17477
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58831
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03859
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70065
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845249
TE10	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05558
FOXM1	ENCODE Transcription Factor Targets	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	4.7232
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863402
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
JHOS4	CCLE Cell Line Gene Expression Profiles	1.0	1.56326
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70379
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVISE	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5892
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63714
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3646
skimmianine-5766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214954
recessive	GeneRIF Biological Term Annotations	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5
erk	Phosphosite Textmining Biological Term Annotations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13264
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GSE134029_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5199
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47155
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nephrocalcinosis	HPO Gene-Disease Associations	1.0	null
HSC5	DepMap CRISPR Gene Dependency	1.0	2.73312
nitriles	Phosphosite Textmining Biological Term Annotations	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.24
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24453
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39396
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42567
Tooth germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.696
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2627
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9877
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65462
renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962334
IGROV1	CCLE Cell Line Gene Expression Profiles	1.0	1.4946
Xanthinuria type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874452
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5132
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7942
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20957
CFPAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26933
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13955
BRD-K28811650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34766
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2031
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
COV504	CCLE Cell Line Gene Expression Profiles	1.0	1.41458
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17231
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91401
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.943
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06018
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73983
MAX	ENCODE Transcription Factor Targets	1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
end stage renal failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.909787
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
BRD-K30358777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2004
bicellular tight junction assembly	GO Biological Process Annotations 2023	1.0	null
hsa-miR-219-1-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904418
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
disease	GWASdb SNP-Disease Associations	1.0	0.031576
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.21214
hypoparathyroidism-retardation-dysmorphism syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-921	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33199
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934097
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00967
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1884
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29825
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3171
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990449
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Salivary gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
decreased body weight	HPO Gene-Disease Associations	1.0	null
LB2241-RCC	GDSC Cell Line Gene Expression Profiles	1.0	1.88249
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43338
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
nephrocalcinosis	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946691
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78088874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18695
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58418
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100512_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04352
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07658
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888289
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75715
Mucinous ovarian adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
PHA-00745360-3827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07449
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-377	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36961619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10887
RGL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78106
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03518
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0074
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07176
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07103
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.258381
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
five	GeneRIF Biological Term Annotations	1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
months	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	2.28056
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11864178-sciadv.adq1724_sm.pdf-13-FOXL2_FOXL2	Rummagene Transcription Factor Associations 2026	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60419
FOXM1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7q11.23 duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962869
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84851
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
BRD-K99125195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96342
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89328
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87542
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
RERFLCSQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50693
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37284
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03495
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
polycystic kidney	MPO Gene-Phenotype Associations	1.0	null
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15825
Distal arthrogryposis type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
affect	GeneRIF Biological Term Annotations	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
abnormal magnesium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
BRD-K42465630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02342
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39664
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A65592966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15088
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.550365
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30589
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95105
renal tubular acidosis	HPO Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24152
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33114
divalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_14396_KO_SYK_SRP124678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920519
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07564
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.4513
hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388909
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5087
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24613
renal magnesium wasting	HPO Gene-Disease Associations	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91106
hsa-miR-4771	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
USF1	ENCODE Transcription Factor Targets	1.0	null
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
BRD-A57457448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50062
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.47
BRD-K68087668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02466
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853092
apical junction assembly	GO Biological Process Annotations 2023	1.0	null
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45674
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.18456
excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95876
BRD-K83341545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24068
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31933
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
BRD-K79555018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22201
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92441
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52488
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1548
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27744
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54546
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931965
truncating	GeneRIF Biological Term Annotations	1.0	null
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67627
welldifferentiated	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
recurrent infections	HPO Gene-Disease Associations	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
decreased circulating magnesium level	MGI Mouse Phenotype Associations 2023	1.0	null
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51071
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03048
PMC11576434-DataSheet1.pdf-18-ASH1L_ASH1L	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.343
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00364
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GID8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7728
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8923
interstitial nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210253
cell adhesion	GO Biological Process Annotations 2015	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051915
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842491
Weight Gain	CTD Gene-Disease Associations	1.0	1.13449
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37208
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
increased circulating parathyroid hormone level	MPO Gene-Phenotype Associations	1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K05957858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30859
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
compared	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0903
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Interstitial nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
STAU1_DELETION_GDS3370_56_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K06863452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02537
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42688
Kenny-Caffey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
ESR1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82401173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45323
BRD-K82521339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19188
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895979
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54699
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849036
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41296
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27182
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08966
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
abnormal drinking behavior	HPO Gene-Disease Associations	1.0	null
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
Cell-cell junction organization	Reactome Pathways 2014	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69447
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
Magnesium	HMDB Metabolites of Enzymes	1.0	null
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40245
BRD-K58149231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18026
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bartter disease type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
paracellular	GeneRIF Biological Term Annotations	1.0	null
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
abdominal symptom	HPO Gene-Disease Associations	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937785
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.10459
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
U031	GDSC Cell Line Gene Expression Profiles	1.0	1.75532
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01096
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215147
BRD-K36544054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82532
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13027
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41221
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30628
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.23169
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
feeding difficulties in infancy	HPO Gene-Disease Associations	1.0	null
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57778236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20833
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal urinary electrolyte concentration	HPO Gene-Disease Associations	1.0	null
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.58322
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22454
DJM-1	GDSC Cell Line Gene Expression Profiles	1.0	1.43233
Brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18549
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K10541973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24862
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04321
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9591
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
homozygosity	GeneRIF Biological Term Annotations	1.0	null
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16386
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27463
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05599
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
lead	GeneRIF Biological Term Annotations	1.0	null
BRD-K90092568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98405
phosphothreonine	Phosphosite Textmining Biological Term Annotations	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
PMC6533083-elife-44306-supp4.xlsx-Table_S4-Supplementary_File_4_PAX8_gene_signature_expression_PAX8	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A24369193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19441
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11666748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28066
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8681
increased circulating parathyroid hormone level	MGI Mouse Phenotype Associations 2023	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
indicating	GeneRIF Biological Term Annotations	1.0	null
nystagmus	HPO Gene-Disease Associations	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07496
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypoparathyroidism	HuGE Navigator Gene-Phenotype Associations	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237216
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52067
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
abnormality of cholesterol metabolism	GWASdb SNP-Phenotype Associations	1.0	0.385329
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67982
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.949101
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63323
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02377
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
hsa-miR-621	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Renal hypomagnesemia 5 with ocular involvement	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.466
system process	GO Biological Process Annotations 2015	1.0	null
patient	GeneRIF Biological Term Annotations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
initial	GeneRIF Biological Term Annotations	1.0	null
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13974
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8577
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.988662
Cell-Cell communication	Reactome Pathways 2024	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16396
growth abnormality	HPO Gene-Disease Associations	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hymecromone-3383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K31952722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33535
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31097
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
monoatomic cation homeostasis	GO Biological Process Annotations 2023	1.0	null
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11978
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08471
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21874
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38202
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052532
abnormality of urine calcium concentration	HPO Gene-Disease Associations	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221291
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02892
fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337608
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
leading	GeneRIF Biological Term Annotations	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	3.02451
BRD-K57639176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87001
BRD-K24382357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53514
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828106
BRD-K34456337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73912
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	6.75471
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9638
Fatty Liver	CTD Gene-Disease Associations	1.0	1.09366
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diagnosis	GeneRIF Biological Term Annotations	1.0	null
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44167
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5071
DB	CCLE Cell Line Gene CNV Profiles	1.0	2.25978
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974588
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
Astigmatism	DisGeNET Gene-Disease Associations	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.30299
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26568
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268237
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59231
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868385
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	0.837781
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.05258
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
PK8	DepMap CRISPR Gene Dependency	1.0	2.56464
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43176
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68124
myopia	HPO Gene-Disease Associations	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
SNU899	CCLE Cell Line Gene CNV Profiles	1.0	1.53566
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
abnormality of purine metabolism	HPO Gene-Disease Associations	1.0	null
NCCIT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82477
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
had	GeneRIF Biological Term Annotations	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
despite	GeneRIF Biological Term Annotations	1.0	null
abnormal urine cytology	HPO Gene-Disease Associations	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.42669
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16348
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38596
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02433
detected	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Renal hypomagnesemia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2015	1.0	null
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34405
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35296
Renal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chronic kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.88434
PMC11328548-mmc1.pdf-8-BNC2_1_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
X-linked recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.88
occluding junction	GO Cellular Component Annotations 2015	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311145
occluding junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053238
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38714
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
FOSL1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.75
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9517
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16594
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.57846
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30326
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045499
Eye-epithelial cell of lacrimal sac	Tabula Sapiens Gene-Cell Associations	1.0	-0.0404207
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	5.53023
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897052
Perturb_3685_KD_MEX3A_SRP321087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04626
astigmatism	HPO Gene-Disease Associations	1.0	null
BRD-K21819164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1022
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3056
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828508
establishment of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20934
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2023	1.0	null
BRD-K87073572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40169
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematuria	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_14253_KD_QKI_SRP272585	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9185
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
channels	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01514
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02055
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33631
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2283
tight junction assembly	GO Biological Process Annotations 2025	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.869757
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06016
Tight junction interactions	Reactome Pathways 2014	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell junction organization	Reactome Pathways 2024	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22226
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27295
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77392
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
BRD-A32128687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13713
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.688692
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7390-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60598
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8384
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920726
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-595	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28982281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44607
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57527
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35411
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29917
phosphoserine	Phosphosite Textmining Biological Term Annotations	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.438146
ZSCAN22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79973
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03076
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1051
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
tight junction	LOCATE Curated Protein Localization Annotations	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
Anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68991
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.70044
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.546
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary hypomagnesemia	ClinVar Gene-Phenotype Associations	1.0	null
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36399
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-125-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.48476
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824818
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5172
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14805
hypermagnesiuria	HPO Gene-Disease Associations	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01968
Serous cystadenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04528
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65045
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99308
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63672
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26511
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45193
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04438
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
JUN-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44568
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05799
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
chr3_190337243_C_G_b38	GTEx eQTL 2025	1.0	2.5078
ovcar-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hyperaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
depletion	GeneRIF Biological Term Annotations	1.0	null
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169099
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12955
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27914
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854722
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35828
S-117	GDSC Cell Line Gene Expression Profiles	1.0	1.4986
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98842
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24142
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.34971
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045685
DMD_Deficiency_GDS2996_614_mouse_Cardiac muscles from 10.5-month (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RNASE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499111
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18303
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831296
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49935
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
cellular process	GO Biological Process Annotations 2015	1.0	null
TF1	DepMap CRISPR Gene Dependency	1.0	2.99283
Manz Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BRD-K61022988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29927
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00536
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.8551
Renal hypomagnesemia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51616
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04902
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043985
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.975804
modulates	GeneRIF Biological Term Annotations	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7557
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13878
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48717
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53317
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67676
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.127541
responsible	GeneRIF Biological Term Annotations	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3487
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
BMI-1_DEPLETION_GDS2445_115_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.27098
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
BRD-K28268716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80385
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02648
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.88952
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977229
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26045
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050931
hypomagnesemia	HPO Gene-Disease Associations	1.0	null
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52919
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64205
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Calcium	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53765
CAOV-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.18389
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71404
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09943
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.204
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
CRCGN008_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0072
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28017
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97236
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24247
kidney cysts	MPO Gene-Phenotype Associations	1.0	null
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41751
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.462
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58237252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83052
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
hsa-miR-4706	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
sodium	Phosphosite Textmining Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24709
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19763
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28682
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82603
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inner dental epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
BRD-K79547691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07106
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13485
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homosalate-4355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21935
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29254
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.43113
Perturb_14614_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.43732
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8952
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990155
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988698
rectal	GeneRIF Biological Term Annotations	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87527
GSE195568_2_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9566
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.56725
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
ATF3	ENCODE Transcription Factor Targets	1.0	null
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01236
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGROV1	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
SNU119	CCLE Cell Line Gene Expression Profiles	1.0	2.51214
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0595
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69111
PMC5356793__F4	PFOCR Pathway Figure Associations 2024	1.0	null
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88138
receptortransfected	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829932
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9651
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73974
H2BK20ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
movement	GeneRIF Biological Term Annotations	1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30861
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.826336
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K47947160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53894
consanguineous	GeneRIF Biological Term Annotations	1.0	null
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059449
BRD-K79995507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02662
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
Adenine phosphoribosyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851476
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09883
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963495
BRD-K75073374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71608
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59542165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52035
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell adhesion molecule (CAM) interaction	KEGG Pathways 2026	1.0	null
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72261
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
BRD-K00797068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37475
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15876
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22501
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0171
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.646574
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984912
BRD-K26376097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34762
PCI-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
selectivity	GeneRIF Biological Term Annotations	1.0	null
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
COLO775	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50575
autosomal	GeneRIF Biological Term Annotations	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09838
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.738271
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12305
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28381
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OV56	CCLE Cell Line Gene Expression Profiles	1.0	1.3914
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.3814
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08032
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	GeneRIF Biological Term Annotations	1.0	null
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61285
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
constitutes	GeneRIF Biological Term Annotations	1.0	null
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20412
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.85762
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.67377
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
496100627_TCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03293
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100610_TCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2415
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04184
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37585
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
studied	GeneRIF Biological Term Annotations	1.0	null
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03811
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59694
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.66022
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886334
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903971
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.993249
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
loss	GeneRIF Biological Term Annotations	1.0	null
BRD-K15291808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61484
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01678
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939374
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51393
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17387
Parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96723
ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190168
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78367
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.176485
mg2	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18052
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15507
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905468
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48946
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.386
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04602
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
BRD-K02078984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29628
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96723
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603295
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23646
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
abnormal vitamin D level	MGI Mouse Phenotype Associations 2023	1.0	null
fluphenazine-3194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypocitraturia	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-4461	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
abnormal calcium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881988
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48005
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866103
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K77808555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39078
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4681	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41847
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02055
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.077
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07408
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09786
ATF3_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERG_01_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.13452
Necrosis	CTD Gene-Disease Associations	1.0	1.50979
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68023
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059601
elevated	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58861
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19921
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041774
MYC	ENCODE Transcription Factor Targets	1.0	null
Hypercalciuria, childhood, self-limiting	ClinVar Gene-Phenotype Associations	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-0.840317
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28478
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5416
paracellular transport	GO Biological Process Annotations 2025	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08515
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66253
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965277
FOXM1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.76325
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15934
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851562
BRD-K76351135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22937
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nonsense	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.87253
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.301
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02256
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06141
BRD-K82324807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63995
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18773
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
BRD-A69648159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18786
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37372
CRCGN015_MCF10A_48H:H11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07165
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17477
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16987
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839003
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52893
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45798
EMC-BAC-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.18389
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32394
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14259
Rickets	DisGeNET Gene-Disease Associations	1.0	null
onset	GeneRIF Biological Term Annotations	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
PANC0327	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45698
Inward rectifier potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7037
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_FOXP1_21924763	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865131
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897751
OAW-28	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
heterozygous	GeneRIF Biological Term Annotations	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.578883
BRD-K40228218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01382
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46383
BRD-K48756106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96636
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080646
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.485
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26947
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44982
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11819
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.18455
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08425
native	GeneRIF Biological Term Annotations	1.0	null
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14085
BRD-K24532125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49791
SELENOI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41635
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
POU3F2	ChEA Transcription Factor Targets	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91539
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14904
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K68055156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71253
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26549
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5699
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54352
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705583
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06281
stomach_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65988
TEAD4_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00345
HUPT4	DepMap CRISPR Gene Dependency	1.0	2.75919
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
BRD-K21927299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06884
onset	HPO Gene-Disease Associations	1.0	null
BRD-K92520489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01701
JUND-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
PHA-00851261E-3965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24048
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oaw42	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37013
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
Dent Disease	DisGeNET Gene-Disease Associations	1.0	null
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046445
PMC7720404__F1	PFOCR Pathway Figure Associations 2024	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16831
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
TEAD4	ENCODE Transcription Factor Targets	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30382953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3363
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5078
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85179
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56583
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840461
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Jalili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82045
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.903766
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8435
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059344
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01884
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K43624274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62863
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83276573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97743
CRCGN016_MCF10A.TP53.M_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16175
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
Polyuria	DisGeNET Gene-Phenotype Associations	1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Amelogenesis Imperfecta	DisGeNET Gene-Disease Associations	1.0	null
JUN_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051356
nephrolithiasis	HPO Gene-Disease Associations	1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.863986
Sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34518
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
plasma	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20313
Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11623
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
increased urine calcium level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94483
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.632384
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4787
PTBP1_02_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.96963
BRD-K74114857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13129
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
NCI-H1975	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34305
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.63588
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43213
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28251
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58899
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.527
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33136
BRD-K19965080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23156
PMC10534007-Table_2.xlsx-S5_unique_up_MSC_B-721_elements_included_exclusively_in_BFTC905_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:K17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0509
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypomagnesemia 3, renal	OMIM Gene-Disease Associations	1.0	null
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34608
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865157
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01952
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.051107
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
Kenny-Caffey syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87363
Heart Diseases	CTD Gene-Disease Associations	1.0	1.02858
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44319
biological adhesion	GO Biological Process Annotations 2015	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64322
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83271
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52464
BRD-K90474764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34419
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900202
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13241788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9362
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497826
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1077	CCLE Cell Line Gene Expression Profiles	1.0	1.35045
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74937
BRD-A69097282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43606
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48299
biomarker	GeneRIF Biological Term Annotations	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41072
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953281
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7849
BRD-K98272474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63446
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90325
abnormality of the curvature of the cornea	HPO Gene-Disease Associations	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59783
betahistine-4956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1852
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chorioretinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
NCI-H1648	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36799
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36866
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27364
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	1.67762
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49303
BRD-K42400613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13193
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70254692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17516
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
three	GeneRIF Biological Term Annotations	1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71778
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
protein-kinase-inhibitors	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057282
PMC5572672__F2	PFOCR Pathway Figure Associations 2023	1.0	null
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21452
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
PANC0504	DepMap CRISPR Gene Dependency	1.0	3.70555
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93254
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54148
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91972
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863974
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1678
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874697
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3327
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	1.8113
large	GeneRIF Biological Term Annotations	1.0	null
BRD-K25484053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49075
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0074
BRD-K01853388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50068
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
abnormal renal calcium reabsorption	MGI Mouse Phenotype Associations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
Uric acid urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1373
Medullary Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
Rectum adenocarcinoma_READ_TCGA-AG-3592-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47884
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855939
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49867
abnormality of ion homeostasis	HPO Gene-Disease Associations	1.0	null
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12127
all	GWASdb SNP-Phenotype Associations	1.0	0.030577
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.66049
strabismus	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14865132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15486
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4417
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37377
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.69
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
BRD-K34069025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40067
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997446
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44918
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal ion transport	GO Biological Process Annotations 2015	1.0	null
5637	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63884
esrra_19901197_kidney_lof_mouse_gpl1261_gse16623	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.04196
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80622162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48163
Teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
Familial hypocalciuric hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.28486
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8183
YY1	ENCODE Transcription Factor Targets	1.0	null
Tight junction	KEGG Pathways 2026	1.0	null
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bicellular tight junction	GO Cellular Component Annotations 2023	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.252744
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19009
capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2559
apical junction complex	GO Cellular Component Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
obesity	GWASdb SNP-Phenotype Associations	1.0	0.550365
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78933
HEYA8	DepMap CRISPR Gene Dependency	1.0	2.44019
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95255
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22107
JUN_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-1.18455
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-582-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90059
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.291
Enamel epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1397
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
PMC8904372-10552_2021_1543_MOESM1_ESM.doc-0-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67456
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81337
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30188
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84957
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5322
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93609
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13344
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
cldn19	GeneRIF Biological Term Annotations	1.0	null
metal ion transport	GO Biological Process Annotations 2023	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03103
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukocyte transendothelial migration	KEGG Pathways 2026	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE180468_2_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
mediates	GeneRIF Biological Term Annotations	1.0	null
Intestinal hypomagnesemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.219
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91502
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977315
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54546
Dental enamel hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31828
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
palmatine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24501
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4029
tubular	GeneRIF Biological Term Annotations	1.0	null
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
Renal agenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859956
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85144
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17595
BRD-K19862308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72909
BRD-K21332842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25116
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58499
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.022
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70849
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995845
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of magnesium homeostasis	HPO Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20236
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895979
Gitelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.361
SREBP-SCAP-Insig complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
membrane	Phosphosite Textmining Biological Term Annotations	1.0	null
Renal Tubular Acidosis	DisGeNET Gene-Phenotype Associations	1.0	null
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52963
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2025	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20116
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
gitelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.527676
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06667
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18753
SNU-423	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77557
microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177863
CEP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61051
Urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.87441
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
renal	GeneRIF Biological Term Annotations	1.0	null
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02356
hsa-miR-514b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suggested	GeneRIF Biological Term Annotations	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28478
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872486
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892234
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84544
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
chrysophanic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01423
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14119
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165001
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54736
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955771
hypoparathyroidism-deafness-renal disease syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904691
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25637
Hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
SPAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14423
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19741
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
cellular cation homeostasis	GO Biological Process Annotations 2015	1.0	null
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.012
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	1.0	2.15729
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08104
BRD-A80035237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25802
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5921
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.909514
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Vitamin D-dependent rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05413
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45885
TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.618
homozygous	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40611
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.826745
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12063
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
SARS-CoV_72Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.24678
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15666
act	GeneRIF Biological Term Annotations	1.0	null
RIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1365
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
BRD-K95018971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26539
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904593
obesity	GWASdb SNP-Disease Associations	1.0	0.64532
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893762
Cell-Cell communication	Reactome Pathways 2014	1.0	null
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24796
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HE-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11876
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
dental caries	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160021
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.992
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07153
abnormal circulating mineral level	MPO Gene-Phenotype Associations	1.0	null
Loop of Henle cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.94084
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852563
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.70396
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31168
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40894
OVCAR-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
multiple	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
extracellular magnesium concentration	GAD Gene-Disease Associations	1.0	null
ADAM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522686
Cornified envelope formation	KEGG Pathways 2026	1.0	null
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06079
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82581
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
hypermetropia	HPO Gene-Disease Associations	1.0	null
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864934
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
a2780cis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94448
BRD-K78202004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02331
abnormal fat-soluble vitamin level	MPO Gene-Phenotype Associations	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868164
BRD-K61053165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08916
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52391
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.425726
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12496
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042315
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849073
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07350528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45832
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95847
Parathyroid hormone secreting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
Omphalocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Papillary Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
canine	Phosphosite Textmining Biological Term Annotations	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12496
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
breast	GeneRIF Biological Term Annotations	1.0	null
abnormal circulating magnesium level	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20795
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43799
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
lysosomal	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant hypocalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.307
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.63878
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	2.56703
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8545
Familial hypocalciuric hypercalcemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0752
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2339
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM52PE	DepMap CRISPR Gene Dependency	1.0	5.00613
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.820458
CHD2	ENCODE Transcription Factor Targets	1.0	null
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26682
magnesium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
unusual	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917511
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.18455
hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.355972
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84833
MAFF	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952114
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21198
BRD-K34445019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03333
Tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47276
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01662
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
homeostatic process	GO Biological Process Annotations 2015	1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46752
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.19052
BRD-K77490065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09913
markedly	GeneRIF Biological Term Annotations	1.0	null
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
KDM1A_KD_GDS5055_457_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04465
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927615
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.71005
Bartter disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
hsa-miR-132	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
siblings	GeneRIF Biological Term Annotations	1.0	null
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02134
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942639
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97461
TE11	DepMap CRISPR Gene Dependency	1.0	2.08016
monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
BRD-K16852474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15556
BRD-K44061011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31236
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5033
DIFI	DepMap CRISPR Gene Dependency	1.0	3.07385
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.16089
BRD-K19009697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80271
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829702
abnormal urine calcium level	MPO Gene-Phenotype Associations	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02313
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63847
BRD-K24529791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07289
magnesium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70361
BRD-K85275903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19822
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53496
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11579
rare	GeneRIF Biological Term Annotations	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.74032
Eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26757
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53807
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
result	GeneRIF Biological Term Annotations	1.0	null
azotemia	HPO Gene-Disease Associations	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12362
HCC1395	CCLE Cell Line Gene Expression Profiles	-1.0	-3.98545
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47289
HLF	DepMap CRISPR Gene Dependency	1.0	2.66682
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18579
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1326
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63008
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99974
Mouselcells	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.51545
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904593
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.6439
occluding junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.0206
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
PMC10929187-ijbsv20p1547s4.xlsx-JQ1-dep_XBP1_signature-ABLIM3_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
BRD-K39396484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04378
load	GeneRIF Biological Term Annotations	1.0	null
BRD-K87044635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96784
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58338
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063833
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898837
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1654
Claudin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8236
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDZ domain binding	GO Molecular Function Annotations 2025	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82601
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92294
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13773
hsa-miR-216b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-3160-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51735
BRD-K03361106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95606
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.523
CNFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04028
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.67909
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87343552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35404
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
cyclic-amp-dependent-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperuricemia	DisGeNET Gene-Disease Associations	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84902
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97888
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3664
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77908
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35334
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880277
Ureteral Obstruction	DisGeNET Gene-Phenotype Associations	1.0	null
Feeding Difficulties In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
u0126	Phosphosite Textmining Biological Term Annotations	1.0	null
PARP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41533
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80721
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952454
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232386
BRD-K91854399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0693
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79678
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	HPO Gene-Disease Associations	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
DoTc2-4510	GDSC Cell Line Gene Expression Profiles	1.0	1.62163
Cell junction organization	Reactome Pathways 2014	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.180339
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45956
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11756
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39472
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867507
SJRH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70103
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.74003
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34803
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09907
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86248
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06097
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04867
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	3.18315
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60466
BRD-K48749255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03396
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948839
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80233876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19798
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84117
hsa-miR-1256	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75826
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054636
Bartter disease type 4a	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
Erectile dysfunction_Penis Erectile Tissue_GSE2457	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.28608
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
KYSE70	DepMap CRISPR Gene Dependency	1.0	2.35143
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46057
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.058
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23562
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_22_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77831
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14228
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194045
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metastasis	GeneRIF Biological Term Annotations	1.0	null
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11062
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15325
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13994
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
GATA3	ENCODE Transcription Factor Targets	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43236
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63099
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19319
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26172
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
abnormality of divalent inorganic cation homeostasis	HPO Gene-Disease Associations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37271
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040874
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.828
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial	Phosphosite Textmining Biological Term Annotations	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	3.06513
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
recurrent urinary tract infections	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22406
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917794
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36319
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.37592
TP63	ChEA Transcription Factor Targets	1.0	null
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21053
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
CBX3_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apical junction assembly	GO Biological Process Annotations 2025	1.0	null
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875052
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66288
MDCK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93274
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
A172	BioGPS Cell Line Gene Expression Profiles	1.0	0.992905
Kidney_CT1_Cortical Thick Ascending Limb Cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
machinery	GeneRIF Biological Term Annotations	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.776635
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6776
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41058
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.724313
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A94366206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2585
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49581
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0203	DepMap CRISPR Gene Dependency	1.0	2.58139
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07218
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AB-01B-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62967214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22837
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14642
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5566
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090109
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55075
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
pka-dependent	Phosphosite Textmining Biological Term Annotations	1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38625
atherosclerosis	GWASdb SNP-Disease Associations	1.0	0.76125
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78362
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13989
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54197
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79849
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93806272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37739
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15703
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.95276
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23266
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904593
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52911
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0884
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00952
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836184
BRD-K80996561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47313
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
RVH421	DepMap CRISPR Gene Dependency	1.0	2.9405
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05015
parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.308842
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMI1_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NI-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84349
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65758
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58804
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2025	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25823
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06166
rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.580439
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943018
hypomagnesemia	GeneRIF Biological Term Annotations	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.532701
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.43026
extracellular	GeneRIF Biological Term Annotations	1.0	null
Urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.939
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36192
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48271
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K69585439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44536
BRD-K61039403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26105
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NOMO-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52267
seizures	HPO Gene-Disease Associations	1.0	null
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05363
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94301
teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068129
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Polydipsia	DisGeNET Gene-Phenotype Associations	1.0	null
PMC10929187-ijbsv20p1547s3.xlsx-XBP1-dependent_genes-AARS_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
loop	GeneRIF Biological Term Annotations	1.0	null
magnesium ion transport	GO Biological Process Annotations 2015	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38724
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24435
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.033852
abnormality of nucleobase metabolism	HPO Gene-Disease Associations	1.0	null
cell-cell junction	GO Cellular Component Annotations 2025	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05319
BRD-K14262397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20444
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86265
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83025
monoatomic cation transport	GO Biological Process Annotations 2023	1.0	null
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63244
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.77463
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.477
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13013
BRD-K32018176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87118
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49697
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497826
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42543
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97494
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06482
component	GeneRIF Biological Term Annotations	1.0	null
tight junction	GO Cellular Component Annotations 2025	1.0	null
bicellular tight junction assembly	GO Biological Process Annotations 2025	1.0	null
SRC_activemutant_51_GSE15815	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.47648
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14442
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70676
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.219235
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.383559
hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.116857
PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945083
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Hyperopia	DisGeNET Gene-Disease Associations	1.0	null
Xanthinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
BRD-K26399271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09426
496100667_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11971
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14295
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13264
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55629
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Hepatitis C	KEGG Pathways 2026	1.0	null
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48471
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
treatment	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3567
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
reveals	GeneRIF Biological Term Annotations	1.0	null
19399471-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.006661
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19039
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34143
proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.363716
THBD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50735
BRD-A94740628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35925
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46976
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080646
GSE180468_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91272
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48305
BRD-K36812047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24133
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
PMC5614556-elife-28652-fig2-data3.xlsx-HSF1_TMP-GeneSymbol_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.31
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15936
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K10452371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0578
abnormal renal calcium reabsorbtion	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
Pseudopodium membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19458
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.83
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07404
RAJI	DepMap CRISPR Gene Dependency	1.0	2.53206
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34053
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09984
one	GeneRIF Biological Term Annotations	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amelogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.925865
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
who	GeneRIF Biological Term Annotations	1.0	null
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54357
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64448
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24985
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
A388	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16706
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054655
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963944
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
missense	GeneRIF Biological Term Annotations	1.0	null
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32428
CRCGN010_HEPG2_24H:D12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03735
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
BRD-K77316284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50275
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
BRD-M01343043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43782
magnesium	GeneRIF Biological Term Annotations	1.0	null
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7975
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49233
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23785
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99101
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
BRD-A27844016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51522
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47285393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18976
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
BRD-K01709173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44546
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.89754
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39645
familial	GeneRIF Biological Term Annotations	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955252
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
compound	GeneRIF Biological Term Annotations	1.0	null
children	GeneRIF Biological Term Annotations	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.56729
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7609
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3455
ACSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58383
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07258
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951364
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0609
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16892
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41859
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17717
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5048
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BICR22	DepMap CRISPR Gene Dependency	1.0	2.11735
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0615
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15139
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54516
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.008
Gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40114
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	3.55128
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89248
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15565
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72316
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21125528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80372
hematuria	HPO Gene-Disease Associations	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79568363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33156
BRD-K59922784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76669
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0278
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77648
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895905
clinical modifier	HPO Gene-Disease Associations	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.83485
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08626
KLE	CCLE Cell Line Gene Expression Profiles	1.0	2.03329
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.09681
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63417
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18493
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33669
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9275
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
Perturb_8816_KD_INTS12_SRP073445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.42114
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08496
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5794
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04932
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15719
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20364
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02081
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
failure to thrive	HPO Gene-Disease Associations	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1933
SMAD3	MotifMap Predicted Transcription Factor Targets	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.23463
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6215
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05865
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04409
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051946
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85777
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938161
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
abnormality of calcium homeostasis	HPO Gene-Disease Associations	1.0	null
BRD-K60782883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61278
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994502
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.980952
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20986
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07526
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4985
Hereditary hypophosphatemic rickets with hypercalciuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0005
Glomerular endothelium fenestra	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05627
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.60813
BRD-K11016405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03257
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64729
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82607
BRD-K55072060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11613
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Kidney_CT1_Cortical Thick Ascending Limb Cell	HuBMAP ASCT+B Annotations	1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72875
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3	ChEA Transcription Factor Targets	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103462
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TEX14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464992
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38722
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
six	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4513	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Chronic progressive external ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05181
Visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.263
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29515
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
BRD-K83775558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.628
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04082
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11997
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25964
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.85037
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4799-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
Factor XIII deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
hsa-miR-489	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
SP1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4776-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Abdominal Pain	DisGeNET Gene-Phenotype Associations	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tight junction	KEGG Pathways	1.0	null
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
bicellular tight junction	GO Cellular Component Annotations 2025	1.0	null
BRD-K47062996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63811
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Uric acid nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36764343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2947
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995796
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47344
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69927
CRCGN014_HEPG2_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14274
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28029
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27137352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17495
acidosis	HPO Gene-Disease Associations	1.0	null
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40911
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.613
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
kidney	HPA Tissue Protein Expression Profiles	1.0	1.90601
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66677
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
BRD-K77214724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20849
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00795
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
BRD-K46951445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71032
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12733
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69617
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43682
recycling	GeneRIF Biological Term Annotations	1.0	null
BRD-A62787624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13553
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20022
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894582
Lung squamous cell carcinoma_LUSC_TCGA-22-1002-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K98940411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33117
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
MYB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00355049
CDK10_knockdown_116_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.76553
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
Hyponatremia	DisGeNET Gene-Phenotype Associations	1.0	null
Primary hypomagnesemia	ClinVar Gene-Phenotype Associations 2025	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41942
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
beyond	GeneRIF Biological Term Annotations	1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02055
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.526
BRD-K95792127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48424
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
decreased	GeneRIF Biological Term Annotations	1.0	null
Hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046402
Heimler syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73983
Eye-conjunctival epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	7.03059
renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59646
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63223
urolithiasis	MPO Gene-Phenotype Associations	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81463
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.40591
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02456
A431	DepMap CRISPR Gene Dependency	1.0	3.20754
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
abnormal vitamin homeostasis	MPO Gene-Phenotype Associations	1.0	null
Perturb_15408_KD_GATA2_SRP043960	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.50693
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
feeding difficulties	HPO Gene-Disease Associations	1.0	null
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.425
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070927
Hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179802
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.71385
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COV318	CCLE Cell Line Gene Expression Profiles	1.0	1.4888
TE14	CCLE Cell Line Gene CNV Profiles	1.0	1.34038
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09833
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
hsa-miR-3167	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.51194
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.65958
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892995
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26823
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65117
Bartter disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.638
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51781
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
protein-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
previously	GeneRIF Biological Term Annotations	1.0	null
BRD-A45349889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26808
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5764
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66336
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57458
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
abnormal mineral homeostasis	MPO Gene-Phenotype Associations	1.0	null
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29036
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894084
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.802
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69558
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.246
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00839
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
Junctional zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047387
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K54179521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48302
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02236
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0568
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UOK101	DepMap CRISPR Gene Dependency	1.0	4.17541
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90359063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3324
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7502
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27859
IGROV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.82045
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74213
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18363
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06675
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22142
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38906
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
LS411N	DepMap CRISPR Gene Dependency	1.0	2.72951
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4398
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95112
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07546
does	GeneRIF Biological Term Annotations	1.0	null
increased purine levels	HPO Gene-Disease Associations	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal renal reabsorbtion	MPO Gene-Phenotype Associations	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5497
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10618
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26442
apical junction complex	GO Cellular Component Annotations 2023	1.0	null
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26762
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18709
BRD-K61335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50936
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941804
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.00194
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
hsa-miR-4704-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
EP300_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ATF3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064817
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3533
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.129715
BRD-K45732260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05636
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51317
IEC-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23616
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.958
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25335
USP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14418
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22482
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73347
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.46349
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.86182
decreased circulating magnesium level	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNKSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13456
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859816
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
disorder	GeneRIF Biological Term Annotations	1.0	null
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.713198
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K11420482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58056
Papillary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.933723
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10733
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37674
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
EFE184	CCLE Cell Line Gene Expression Profiles	1.0	1.42823
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29602
stimulated	GeneRIF Biological Term Annotations	1.0	null
tetany	HPO Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3265
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64875
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.920514
BRD-A55025683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19562
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04304
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.10157
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98452
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962334
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76037
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRC1_BMI_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895979
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34202
transport	GeneRIF Biological Term Annotations	1.0	null
PE/CA-PJ15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-443-ZNF280B_ZNF280B	Rummagene Transcription Factor Associations 2026	1.0	null
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
SMC3	ENCODE Transcription Factor Targets	1.0	null
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77138
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2254
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51152
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.05896
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43056
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.98654
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
BRD-K83108629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32796
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07065
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.45036
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC251	CCLE Cell Line Gene Expression Profiles	1.0	3.40829
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOTCH_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0714
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040273
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31761
cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234878
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
Npas4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8769
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
type	GeneRIF Biological Term Annotations	1.0	null
abnormal urine output	HPO Gene-Disease Associations	1.0	null
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83828
ions	GeneRIF Biological Term Annotations	1.0	null
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
Primary Hypomagnesemia (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
chronic kidney disease	HPO Gene-Disease Associations	1.0	null
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38487
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.543
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5463
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19813
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950184
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887145
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.755974
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31836
EFO-21	GDSC Cell Line Gene Expression Profiles	1.0	2.61184
BRD-K23404017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09884
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18317
Cystinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31076
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15379
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938335
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41588
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09998
PMC12171002-jcav16p2578s1.pdf-64-ZNF234_ZNF234	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
renal tubular dysfunction	HPO Gene-Disease Associations	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
abnormal vitamin d level	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K42453497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23902
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07927
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16457
cell junction	LOCATE Curated Protein Localization Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
dogs	Phosphosite Textmining Biological Term Annotations	1.0	null
renal calcium wasting	HPO Gene-Disease Associations	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62774
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079144
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.511
BRD-K24946605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48988
BRD-K55940699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08662
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
JHOC5	CCLE Cell Line Gene Expression Profiles	1.0	1.94874
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46793
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypercalciuria	HPO Gene-Disease Associations	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18597
Hypomagnesemia	DisGeNET Gene-Disease Associations	1.0	null
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18985
ionselective	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865085
juvenile onset	HPO Gene-Disease Associations	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64883
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15069
cimetidine-4063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048843
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14956
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17717
ok cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.353712
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20554
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3715
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82526
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857451
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16121
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837934
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3375
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0328
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8022
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07496812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25957
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19042
Bicellular tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4248
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20925
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.298214
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
caused	GeneRIF Biological Term Annotations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-A06327019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11783
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20378
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PK-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
insufficiency	GeneRIF Biological Term Annotations	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.47226
hsa-miR-4683	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09648
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23793
CLDN19	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7594-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cystadenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cell-cell junction	GO Cellular Component Annotations 2015	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37055068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41831
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.69556
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
abnormality of acid-base homeostasis	HPO Gene-Disease Associations	1.0	null
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
abnormal kidney physiology	MPO Gene-Phenotype Associations	1.0	null
Pathogenic Escherichia coli infection	KEGG Pathways 2026	1.0	null
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07156
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.246
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01084
BRD-K97237010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20441
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
Hypertrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	3.60098
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71093375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.19786
Hypercalciuria, Childhood, Self-Limiting	DisGeNET Gene-Disease Associations	1.0	null
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73996
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Henles loop cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08201
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21328
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22823
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61046
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06058
intracellular	GeneRIF Biological Term Annotations	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17422
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06716
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11157
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959068
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11328548-mmc1.pdf-8-BNC2_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56094
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80315
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.955987
KYSE30	DepMap CRISPR Gene Dependency	1.0	4.26288
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cldn16	GeneRIF Biological Term Annotations	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82645
interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826586
CAL29	DepMap CRISPR Gene Dependency	1.0	2.76663
metal ion transport	GO Biological Process Annotations 2025	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
hek293	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
unknown	GeneRIF Biological Term Annotations	1.0	null
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35075
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K47511177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02031
abnormality of renal excretion	HPO Gene-Disease Associations	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054788
abnormal urine homeostasis	MPO Gene-Phenotype Associations	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7917
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95201
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27984
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967699
Perturb_9726_KD_SF3B1_SRP278642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSU	DepMap CRISPR Gene Dependency	1.0	3.02721
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.199008
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058491
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82138
BRD-A14878925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63729
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30533
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.85957
Wasting	DisGeNET Gene-Disease Associations	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75983763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01704
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8091
Apical junction complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39153
butadienes	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2654
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
decreased urine ph	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4735-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35394
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fusiform gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856745
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
BRD-K54922310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07088
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56556
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50262
membrane	GO Cellular Component Annotations 2015	1.0	null
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40194
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6365
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amelogenesis imperfecta type 1J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GI-ME-N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62134
BRD-K29264158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73915
Claudin-16	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20156
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30706
Mammary ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12593
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Developmental and epileptic encephalopathy 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.812
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95382
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053181
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42044
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.34915
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Recurrent Urinary Tract Infection	DisGeNET Gene-Disease Associations	1.0	null
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31626
early	GeneRIF Biological Term Annotations	1.0	null
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04562
Breast invasive ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4046
abnormal urine citrate concentration	HPO Gene-Disease Associations	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9205
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.33711
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.105946
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.63
ONS76	DepMap CRISPR Gene Dependency	1.0	2.9743
BRD-K02610196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01537
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82003
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050422
BRD-K28357534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01842
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K69678391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35246
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TIA1_KO_GSE54418_264_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
ONCODG1	CCLE Cell Line Gene Expression Profiles	1.0	1.47496
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65279
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92796
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50221
hsa-miR-212	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23033
metacetamol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11358
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962334
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A73618687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28389
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964654
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58127
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17109
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36939
single-organism process	GO Biological Process Annotations 2015	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66171
abnormality of cation homeostasis	HPO Gene-Disease Associations	1.0	null
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.434072
BRD-K42799692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3379
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930508
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08841
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27429
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80404
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD15	DepMap CRISPR Gene Dependency	1.0	8.59993
maturity-onset diabetes of the young type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
BRD-K52520268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26231
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-K28774883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43163
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886931
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.14569
GATA2	ENCODE Transcription Factor Targets	1.0	null
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63821
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70547
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87491
BRD-K59975583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30648
degradation	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01075
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888538
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61286
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56756
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14477
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16205
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054516
SKGII	DepMap CRISPR Gene Dependency	1.0	4.67255
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
cation homeostasis	GO Biological Process Annotations 2015	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33544
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
253JBV	CCLE Cell Line Gene Expression Profiles	1.0	1.49656
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	5.45688
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276495
BRD-K67390084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43734
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43966
Pseudohypoaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
Smooth septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11171
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.08066
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.59952
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.14693
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0089
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Initial collecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8119
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66309
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91205
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943645
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878894
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01229
BRD-K82825326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22405
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41863
leukocyte transendothelial migration	KEGG Pathways	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ALOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85915
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27876
Hypermagnesiuria	DisGeNET Gene-Phenotype Associations	1.0	null
NR3C1	ENCODE Transcription Factor Targets	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4379
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345314
SKMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26306
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.99548
FOSL1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26453
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70493
been	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7253-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
Hypercalciuria	DisGeNET Gene-Phenotype Associations	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88489
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K44866331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12738
Dent disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.142
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Claudin	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K24125966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85901
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68799
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.729646
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88077
calciumsensing	GeneRIF Biological Term Annotations	1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962334
renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.893359
NR3C1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961402
transcellular	GeneRIF Biological Term Annotations	1.0	null
BRD-K83475223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02856
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
OAW-28	GDSC Cell Line Gene Expression Profiles	1.0	1.72337
BRD-K70936779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12445
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59725
BRD-K94629607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75935
BRD-K40011635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49705
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORL51	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96018
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879171
Hypocalcemia	DisGeNET Gene-Phenotype Associations	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
abdominal pain	HPO Gene-Disease Associations	1.0	null
abnormal urine magnesium concentration	HPO Gene-Disease Associations	1.0	null
BRD-K76713298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10722
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33559
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3936
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58221
Calcium oxalate nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0399
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.03861
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92355
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962334
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12531
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
abnormal vitamin level	MPO Gene-Phenotype Associations	1.0	null
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65163
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89994
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18374
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
U-2-OS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
decreased urine pH	MGI Mouse Phenotype Associations 2023	1.0	null
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
FOSL1	ENCODE Transcription Factor Targets	1.0	null
PMC7720404__F1	PFOCR Pathway Figure Associations 2023	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15188
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27576
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92007
renal insufficiency	HPO Gene-Disease Associations	1.0	null
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
UACC893	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52512
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.782
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42308
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-7848-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
revealed	GeneRIF Biological Term Annotations	1.0	null
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89972
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43605
OVCAR-3	GDSC Cell Line Gene Expression Profiles	1.0	1.57078
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.868627
hypomagnesaemia	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.61
neoplasms	GeneRIF Biological Term Annotations	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5531
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.148
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46874
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
chr3_190331991_CT_C_b38	GTEx eQTL 2025	1.0	5.06338
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861137
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.297
pka	Phosphosite Textmining Biological Term Annotations	1.0	null
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K21969044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17137
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07794
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37917
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.50037
hsa-miR-4452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41229
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
hypercalciuria	GeneRIF Biological Term Annotations	1.0	null
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
BRD-A64849281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71219
Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
GSE144838_7_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.910552
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74478
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65345
BRD-K43966357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11454
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
turkish	GeneRIF Biological Term Annotations	1.0	null
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4556
bartter disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.783116
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
BRD-K65427501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1781
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65512
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052518
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chemical Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NFIC	ENCODE Transcription Factor Targets	1.0	null
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.47132
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860007
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47504
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31454
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00817
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62906
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31523
glycogen-synthase-kinase-3	Phosphosite Textmining Biological Term Annotations	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
BRD-K53900606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1717
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044543
TALH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6643
mistargeting	GeneRIF Biological Term Annotations	1.0	null
Adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
BRD-K42671829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59309
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2507
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43233
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
hyperuricemia	HPO Gene-Disease Associations	1.0	null
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91449
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6997-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67775
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
TYK-nu	GDSC Cell Line Gene Expression Profiles	1.0	1.56013
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03962
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68452
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86061
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
REST	ENCODE Transcription Factor Targets	1.0	null
HLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21211
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88263
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938723
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.29437
TAF1	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular monoatomic ion homeostasis	GO Biological Process Annotations 2025	1.0	null
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14348
abnormal circulating parathyroid hormone level	MPO Gene-Phenotype Associations	1.0	null
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polydipsia	HPO Gene-Disease Associations	1.0	null
BRD-A86629089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34131
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26979
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7048
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01465
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4376
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.165463
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14966
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082474
WM1799	DepMap CRISPR Gene Dependency	1.0	2.43204
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09584
HCC70	DepMap CRISPR Gene Dependency	1.0	6.79253
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08894
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56836463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27976
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953588
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23033
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.465
Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030621
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33125
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36187
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80746
excretion	GO Biological Process Annotations 2015	1.0	null
hsa-miR-885-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2443
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
MERO25	DepMap CRISPR Gene Dependency	1.0	2.18025
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20973
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.135355
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21269
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01817716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07078
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
HEY	DepMap CRISPR Gene Dependency	1.0	4.68267
Hypomagnesemia	DisGeNET Gene-Phenotype Associations	1.0	null
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85166
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.152546
permeability	GeneRIF Biological Term Annotations	1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42529
BRD-K09460582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20519
cellular chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
PMP-22/EMP/MP20/Claudin superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.42226
trafficking	GeneRIF Biological Term Annotations	1.0	null
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.91267
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10141
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	GDSC Cell Line Gene Expression Profiles	1.0	3.00029
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86122
OAW-42	GDSC Cell Line Gene Expression Profiles	1.0	2.10768
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18487
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.67165
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.754124
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.75453
MFM-223	GDSC Cell Line Gene Expression Profiles	-1.0	-2.9863
cell junction	GO Cellular Component Annotations 2015	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.76125
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54732
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42017
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21487
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061056
BRD-K73206088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39926
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01834
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7536
FOS_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970516
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056095
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25186
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21237
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42917
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
CAKUT	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
BRD-K89116076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55539
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95841
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.29
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55856
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28478
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10644
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08249
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.065
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91428
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53321
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52218
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.355604
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.153281
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050245
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.438
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78219
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
OAW42	CCLE Cell Line Gene Expression Profiles	1.0	2.13022
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12975
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05412
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
conclude	GeneRIF Biological Term Annotations	1.0	null
abnormal urine ph	MPO Gene-Phenotype Associations	1.0	null
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
BRD-K62170825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16926
affecting	GeneRIF Biological Term Annotations	1.0	null
SARS-CoV_48Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.41991
TOLLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615438
MDAMB453	DepMap CRISPR Gene Dependency	1.0	6.61083
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16654
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53348
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077628
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1922
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
BRD-K36460068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87131
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01579
PMC5013636-ncomms12601-s5.xlsx-AP1-Groups_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66152
egyptian	GeneRIF Biological Term Annotations	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899943
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20122
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95263
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell adhesion molecules	KEGG Pathways	1.0	null
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54195
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
Bipolar Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910157