association	dataset	threshold value	standardized value
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053725
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00336
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.53842
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43635
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14728
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.572
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0467
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13415
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46911
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01395
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.11105
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26906
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845766
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15656
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00989
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17272
Prestwick-689-2514	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702717
BRD-K52669647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20467
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80188
Perturb_15189_KD_TP63_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K05475237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15585
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994572
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bed nucleus of the external capsule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67814
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4445
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5382
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68054
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.51605
mephenytoin-5801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16459
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5144
binding	GO Molecular Function Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03053
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042433
cell adhesion molecules	KEGG Pathways	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
midodrine-6804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
foliosidine-6057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96485138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34469
SF172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56733
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00081
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0139
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KRAS.PROSTATE_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
oxolamine-4969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08971733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20259
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43051
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03221986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64179
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal urine homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	3.27375
nimodipine-6320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
caffeic acid-3053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.147
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831324
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9406
BRD-K55144248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.344
PMC5013636-ncomms12601-s5.xlsx-LEF1-Groups_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7041
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06265
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2649
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55584
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45649
ELF5	ChEA Transcription Factor Targets	1.0	null
ATM_01_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58688
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63898
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71727
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905046
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07106
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
EoL-1-cell	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85823
ECC2	DepMap CRISPR Gene Dependency	1.0	2.31084
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18427
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7181
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6678
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80439
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4703
bicellular tight junction assembly	GO Biological Process Annotations 2023	1.0	null
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.817158
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26056
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22408
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16242
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6237
vagina	GTEx Tissue Gene Expression Profiles	1.0	2.16089
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039269
fulvestrant-6867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03492
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841212
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13671
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
minaprine-1468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35033
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00802
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell-cell junction organization	Reactome Pathways 2014	1.0	null
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49114
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	1.60911
TALL1	CCLE Cell Line Gene CNV Profiles	1.0	2.86743
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20968
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42772
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11068
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.852649
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056229
EFO-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.88721
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23666684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0102
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71527
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12174
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03655
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03231
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
trimethobenzamide-4100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Endocrine gland cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1299	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51471
BRD-K47052171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40735
prazosin-3098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78719
rottlerin-825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ifenprodil-2372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fenoprofen-2553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A14484404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09423
fluticasone-4129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26403
Hecv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3187
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
quinostatin-865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cell junction organization	Reactome Pathways 2024	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972658
BRD-K64451058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64898
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44236678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0745
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29486
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05696
MK-886-264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937501
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39742
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7605
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SP-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0877
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25913
SHMAC5	DepMap CRISPR Gene Dependency	1.0	7.30578
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23812
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0296
BRD-K58412301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17209
defined	GeneRIF Biological Term Annotations	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60683
RPMI-2650 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25913
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53145
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15449
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6958
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55752
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.843673
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0013
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36028
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.005
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57255
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28177
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
tight junction	GO Cellular Component Annotations 2015	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2456
BRD-K54549319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94935
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7994
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28154
tretinoin-447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tight junction assembly	GO Biological Process Annotations 2023	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997016
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3364
chlorcyclizine-6053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal kidney morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
enilconazole-5113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.7229
amiprilose-4119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27452
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82172
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.960845
dantrolene-3867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tight junction assembly	GO Biological Process Annotations 2025	1.0	null
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	2.23326
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.43579
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14476
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08661
BRD-K32362211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0282
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.166749
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07002
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4398
PMC11696763-41598_2024_79298_MOESM7_ESM.csv--Table_S1_Differentially_expressed_genes_including_ZNF560_were_screened_out_between_normal_and_tumor_tissues_ZNF560	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11833364-tcr-14-01-340-supplementary.pdf-61-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81481
Calu-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971749
Cell junction organization	Reactome Pathways 2014	1.0	null
SNU626	DepMap CRISPR Gene Dependency	1.0	7.72529
tight junction	GO Cellular Component Annotations 2023	1.0	null
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57952
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.6955
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20685
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0653
clopamide-5402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3765
azaperone-6151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544152
BRD-K96295480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.003
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9531
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.5955
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44301
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24791
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58468
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48118
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53346
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	0.874579
FOS	ENCODE Transcription Factor Targets	1.0	null
BRD-K56590597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01615
BRD-K76420749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15862
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920689
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40933
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38657
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25758
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51036
EW-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.99025
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28644
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29825
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.20539
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05116
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13217
sulfamethoxazole-3667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNMPA-(AM)3-583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3628
N-acetyl-L-leucine-6462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2324
decreased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60874
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3383
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9483
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07304
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24641
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4757
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57998
trazodone-7410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02522
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9622
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30738175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54442
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.537
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10211
eldeline-6026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thiamphenicol-glycinate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56318
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08383
MM160113	DepMap CRISPR Gene Dependency	1.0	2.25863
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9753
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30035
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.74103
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11139
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58368
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74680333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42062
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35143
Kainate selective glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.265
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039612
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10325
Prestwick-664-6033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.853609
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44301
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7331
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.03009
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.59238
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6655
apical junction complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265038
BRD-K21196859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28375
Hepatocellular carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02739
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95448
SC-58125-542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25941
constipation	MGI Mouse Phenotype Associations 2023	1.0	null
mesalazine-5888	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.911649
methacholine chloride-6248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20632
azlocillin-5788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.715869
cell-cell junction assembly	GO Biological Process Annotations 2015	1.0	null
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03118
iopamidol-2732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0933
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959358
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27818
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5278
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31937
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74824
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03245
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.942266
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.74622
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02389
BRD-K75626008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39104
BRD-K12708839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03784
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40318
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46873
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3302
azlocillin-6262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73015
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37736
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930854
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24458
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1839
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
SNU668	DepMap CRISPR Gene Dependency	1.0	6.67031
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.24462
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21749
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7147
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19227
2,6-dimethylpiperidine-4543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8379
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13286
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825148
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98915
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13217
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051496
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	2.0463
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980448
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15103
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898053
Apical junction complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1281
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19825
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4792
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6404
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54089
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calu-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
cldn8	GeneRIF Biological Term Annotations	1.0	null
BRD-K46703028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36848
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
flufenamic acid-316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cell adhesion molecule (CAM) interaction	KEGG Pathways 2026	1.0	null
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71727
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23524
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Claudin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K16468319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15271
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893355
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48304
intermediate stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16268
CAPAN-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43396
wwcc	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3797
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71069
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
BRD-K19672435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49441
increased circulating chloride level	MGI Mouse Phenotype Associations 2023	1.0	null
mexiletine-4338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tight junction interactions	Reactome Pathways 2014	1.0	null
bicuculline-4397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.599
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0776
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03876
Prestwick-692-4599	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55584
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989915
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56748
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motif	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9995
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52775
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9591
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50906
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41654
Number of sexual partners	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9043
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40712
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.326
Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42656
CUX1	ChEA Transcription Factor Targets	1.0	null
BRD-K59455917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15263
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62074
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03363
TCCSUP	DepMap CRISPR Gene Dependency	1.0	4.24486
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1789
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51619
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74513
butein-582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-665-7380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48984
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76368
UMUC3	CCLE Cell Line Gene Expression Profiles	1.0	1.60697
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tight junction assembly	GO Biological Process Annotations 2015	1.0	null
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20972
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22807
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.985995
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50398
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	2.66872
valproic acid-5574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12460934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13845
Striatum ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09978
propoxycaine-3583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.815
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02427
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21039
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72709
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H838	GDSC Cell Line Gene Expression Profiles	-1.0	-2.35553
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11222
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.911184
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94258
layer 3 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05898
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
AURKB_knockdown_92_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.03041
BRD-K88278778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13355
BRD-K34907403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29019
496100313_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.95452
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18449
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00637
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.125
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14077
BRD-K11428617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9508
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5075
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01543
monorden-493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11313
troglitazone-370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41033343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59535
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05347
BRD-K38227596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37065
enilconazole-5538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896041
flupentixol-6708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AKT1_knockdown_123_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.92129
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01237
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69739
Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9386
iloprost-496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3365
YH-13	GDSC Cell Line Gene Expression Profiles	1.0	2.12414
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903192
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02128
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08417
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
GSE102342,GSE102648_1_v_0_curcumin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	0.861715
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4422
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93133
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52319
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91959
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6958
A2780	GDSC Cell Line Gene Expression Profiles	1.0	3.44302
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15704
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87649
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01449
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31445
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93731
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87065
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081206
BRD-K60453579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27629
H3K27me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46933
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01352631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40203
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	0.837071
terguride-6473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adipocyte	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.972787
Prestwick-675-6042	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.42698
GSE145215_2_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9516
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13216
Cell-cell junction organization	Reactome Pathways 2024	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15552
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30471
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27704
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07744
BRD-K77354700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32714
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33361
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73925
cell part	GO Cellular Component Annotations 2015	1.0	null
LU165	DepMap CRISPR Gene Dependency	1.0	4.22737
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4142
fludroxycortide-6039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Immunologic Deficiency Syndromes	CTD Gene-Disease Associations	1.0	1.08868
Tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.976313
KRAS.DF.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08753635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19275
BRD-K80679698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21952
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48237
BRD-K26708780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07866
mRNA_YY1_22210892	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K58118393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69088
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00446
BRD-K99250186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42869
DON cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14548
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LY-294002-5596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01543
BRD-K00765599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15183
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
A2780	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
NCIH1651	CCLE Cell Line Gene Expression Profiles	1.0	1.48564
BICR18	CCLE Cell Line Gene Expression Profiles	1.0	1.39613
breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415773
increased glomerular capsule space	MGI Mouse Phenotype Associations 2023	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
occluding junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.83322
KDM5A	ENCODE Transcription Factor Targets	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03053
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5418
BRD-K93615384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26993
sirolimus-5581	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHP-134	GDSC Cell Line Gene Expression Profiles	1.0	1.91213
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01721
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7236
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.84069
cell-cell junction organization	GO Biological Process Annotations 2015	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.50649
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51271
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42892
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07557
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7685
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94258
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051855
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70284
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46006
flufenamic acid-5059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41839
terazosin-5831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
neomycin-7221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6518
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02789
bacitracin-7448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.236
apical junction complex	GO Cellular Component Annotations 2023	1.0	null
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41469
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9962
alpha-estradiol-403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Apicolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08944
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38693
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K46065636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42402
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83904
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89458
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.809
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30536
BECKER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51375
fulvestrant-7539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	1.77247
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78461
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96119
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4651
cefadroxil-3259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.658742
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
BRD-K25761766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16783
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46282
gemfibrozil-5069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Stratum germinativum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2025	1.0	null
NCIH2110	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8975
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4532
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982371
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24641
perphenazine-1540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904178
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07134
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17269
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02271
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01704
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02128
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40097
BRD-K02395808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06255
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6526
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52377
Pathogenic Escherichia coli infection	KEGG Pathways 2026	1.0	null
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18835
BV173	CCLE Cell Line Gene Expression Profiles	1.0	1.976
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52811
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07433
Junctional zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02789
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95448
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.89433
adiphenine-7279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16933266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43199
Nasal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16214
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21461
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941842
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08171
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49771
Calcium	HMDB Metabolites of Enzymes	1.0	null
Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26978
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.04211
hydroxyachillin-4797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62555617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30241
BRD-K07981644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08147
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49083
NCI-H520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K42138859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2331
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19344
NK-92MI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32043
BRD-K18346873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12193
dexibuprofen-6471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZN-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4012
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1479
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02898
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69323
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
BRD-K93927229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52075
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43345
gramine-4118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00628863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19661
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49236
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090117
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58139
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21737
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13259
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31561
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.952
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12643
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04937
saquinavir-3549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838821
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
spectinomycin-4773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51352
BRD-K94347944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21743
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14443
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909712
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056488
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53145
BRD-K77634878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1314
BRD-K60741970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04338
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1788
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4347
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03628
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852896
BRD-K05902089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04533
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17191
apical junction assembly	GO Biological Process Annotations 2023	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
wortmannin-404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34644
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30427
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08212
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.572
atropine oxide-2054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06008
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.596203
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16856
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07099
Tonsil	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874322
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6852
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.05866
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7919
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85784
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.85467
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13365
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26244
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4657
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.64211
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89957
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15118
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43404
BRD-K19523037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93361
butoconazole-2427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70039231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02741
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.844359
SC-560-6870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49149
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00637
abnormal circulating protein level	MGI Mouse Phenotype Associations 2023	1.0	null
atropine oxide-6812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Stroke	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77398
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24827
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40496
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6031
C99	DepMap CRISPR Gene Dependency	1.0	3.54977
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80668
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02157
TUBB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437543
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1235
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.60079
RKN	CCLE Cell Line Gene Expression Profiles	1.0	1.35623
Virion - Hepatitis viruses	KEGG Pathways 2026	1.0	null
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
nicergoline-2220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.37578
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14317
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11387
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48529
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03822
NCIH2106	CCLE Cell Line Gene CNV Profiles	1.0	1.70601
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9034
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76315
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2023	1.0	null
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29945
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31975
pirlindole-5497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16604405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25622
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03553
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.41641
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841212
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SC-58125-507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2452	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87976
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09494
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atracurium besilate-7477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5623
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02428
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94258
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825148
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20683
LNX1	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.41428
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.572
Cervicovaginal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8912
HS633T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26387
bromopride-4741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63532
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88469
lobeline-5784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54508
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
leukocyte transendothelial migration	KEGG Pathways	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4483
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18715
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16586
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04086
11906190-Table2b-2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17856
ioversol-3365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
selegiline-4065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO Biological Process Annotations 2015	1.0	null
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04621
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02428
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
piribedil-5434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27961
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862704
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971749
oxaprozin-3876	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.758514
pepstatin-4790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46933
gastric	GeneRIF Biological Term Annotations	1.0	null
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pirinixic acid-481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983094
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18899
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.57299
flunisolide-6023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
colchicine-630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66144
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16856
aminohippuric acid-3076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12509
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58164
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.25468
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32765
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	1.44002
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5887
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76297
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9694
valproic acid-629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878145
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17246
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1867
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3769
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40915
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51227
STOCK1N-28457-6869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31021
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02128
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9957
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846986
W-13-440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
nalidixic acid-4691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38901
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.12915
etynodiol-6479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDCK-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89495
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18063
BRD-K53703060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44436
15381369-Table6	GeneSigDB Published Gene Signatures	1.0	null
BRD-K62976536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32542
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.10318
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22737
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63486
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25218
CTCF	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35701
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41416
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35862
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24496
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972658
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903192
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2248
Parabrachial nucleus, lateral division, dorsal lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03921
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08171
BRD-K50851442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73355
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969055
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SBC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63674
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59344
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18272
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051674
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02329
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74004
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16761
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8684
Salt gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40079
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856809
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29476
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876032
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76829
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1097
superficial stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53145
cell-cell junction	GO Cellular Component Annotations 2015	1.0	null
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35885
tinidazole-2568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95019
alpha-estradiol-6970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14631
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10381
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06672
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.74061
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76751
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52903
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10444
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03931
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831088
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12729
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19312
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62311
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.251
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75775
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56439
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K83115435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2162
mycophenolic acid-4137	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfadimidine-2560	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5106
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
methylbenzethonium chloride-3943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49530286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93497
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.57
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1405
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6606
HL-7702 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4804
dantrolene-3786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00944
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32888
0317956-0000-3858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976814
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
monorden-544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58634
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16115
BRD-K57476199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67902
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05418
MHHCALL2	CCLE Cell Line Gene CNV Profiles	1.0	1.69065
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47275094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14883
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36697
Serous adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937501
BRD-K32706281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32425
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41408
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
downregulated	GeneRIF Biological Term Annotations	1.0	null
flurbiprofen-6472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pirinixic acid-464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pars recta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.372
LY-294002-401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873919
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
P30-OHK	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48002
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.07983
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.9075
ABL1_knockdown_137_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44612
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12037
cobalt chloride-383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904178
BRD-K85532500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2589
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2365
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3461
BRD-K37402529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10597
chromosome	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.93209
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.6049
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37375
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2176
Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948265
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08417
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57345
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.33321
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32301
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07956
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
dimethyloxalylglycine-584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Amyotrophic lateral sclerosis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
fulvestrant-6925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43794
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4863
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03997
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939497
ketoprofen-4286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96671994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36792
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23425
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
oxamic acid-439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56763
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40606
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080776
alpha-CP1	MotifMap Predicted Transcription Factor Targets	1.0	null
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
BRD-K73880067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59726
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08417
co-dergocrine mesilate-4071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60063
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.839142
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
thioperamide-5270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56815
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19532
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31426
altretamine-6467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
decreased food intake	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23874
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3674
prazosin-6475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
doxazosin-3024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clustered	GeneRIF Biological Term Annotations	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34444
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2021
apical junction assembly	GO Biological Process Annotations 2025	1.0	null
tolbutamide-2359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53224741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8049
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49707
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06563
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF126	CCLE Cell Line Gene Expression Profiles	1.0	1.94238
nicotinic acid-3043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12245
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02489
novobiocin-437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9019
novobiocin-632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2477
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51036
Tight junction interactions	Reactome Pathways 2024	1.0	null
bicellular tight junction assembly	GO Biological Process Annotations 2025	1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959145
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22147
pipemidic acid-6470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9361
SP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83506
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210925
isocorydine-2780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07589203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03846
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53624506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05891
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4912
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69669
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02367
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52102
BRD-K63212062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33754
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22232
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24731
BRD-K53797069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97438
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24774
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1952
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6704
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.55542
Hepatobiliary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957692
BRD-K93836438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02648
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.38628
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5903-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1_KD_GDS4962_467_human_not specified	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
myosmine-6055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95822658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34109
biological adhesion	GO Biological Process Annotations 2015	1.0	null
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33029
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3718
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25758
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27062
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43863
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53415
BRD-K73739802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01076
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35139
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.71377
UMUC10	DepMap CRISPR Gene Dependency	1.0	4.091
SET2	CCLE Cell Line Gene CNV Profiles	1.0	2.03598
quinidine-5793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10566
membrane	GO Cellular Component Annotations 2015	1.0	null
rofecoxib-463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
timolol-6483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33574
PMP-22/EMP/MP20/Claudin superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34444
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08933
promazine-6028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2097
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10578
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2329
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32339
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0121
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-OV-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5648
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12502
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19107
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12232
Smooth septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34514
oxidative stress	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18018
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49982
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64193
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73861
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7669
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12056
15381369-Table3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K07164317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48897
propantheline bromide-3352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10698156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09839
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09562
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24973
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24533
Perturb_15188_KD_BRG1/BRM_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
estradiol-6718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26028
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.59911
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08383
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37007
BRD-K17705318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19754
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04175
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39739
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830614
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14898
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16958
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU387	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75472
kawain-7369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5574-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKGI	DepMap CRISPR Gene Dependency	1.0	2.11161
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67524
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.13865
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01914
BRD-K18709210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31225
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02823
GSE137928_0_v_1_blebbistatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99641
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44316
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02841
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22045
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38891
Leukocyte transendothelial migration	KEGG Pathways 2026	1.0	null
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31473
pirinixic acid-495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
piracetam-5043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89305325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57105
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47667
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
JHESOAD1	DepMap CRISPR Gene Dependency	1.0	3.3117
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14193
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70705
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13739
GSK3A_KD_GDS4305_180_human_MOLM-14 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	1.0	1.51138
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.72883
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.83526
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.64958
tight junction	KEGG Pathways	1.0	null
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23612
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.03701
M140325	DepMap CRISPR Gene Dependency	1.0	2.03997
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57158
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07214
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23298
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19014
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
econazole-7305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23213
BRD-K08715132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03138
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94213
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51067
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26244
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891938
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19519
dizocilpine-2232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983094
benserazide-631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1155	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95091
BRD-K32760954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05164
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87649
SKN	DepMap CRISPR Gene Dependency	1.0	16.0925
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59671
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25999
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30773
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18506
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31021
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37816
chlorprothixene-2627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19603
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29469
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02797
benzamil-6056	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.462
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50207
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987913
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55236
bretylium tosilate-5020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bromopride-6037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trichostatin A-4348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18814
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922192
Claudin	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K43901257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69619
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9758
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12065
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841212
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12972
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21626
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890836
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937501
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13043
dantrolene-2369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0827
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06147
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60683
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08251
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76789
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49605
cell junction organization	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60602
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5038
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.46001
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
6-benzylaminopurine-2351	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07707
channel activity	GO Molecular Function Annotations 2025	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
BRD-K45888106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19418
BRD-K91239327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0182
HSC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42104
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01237
BRD-K85604751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22194
Cell-Cell communication	Reactome Pathways 2024	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.982757
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46933
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19782
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24357
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34048
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.55569
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.862902
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40915
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01721
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19214
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996411
Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40187
G-361	GDSC Cell Line Gene Expression Profiles	1.0	1.41984
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8687
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35894
acetylsalicylsalicylic acid-6778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08583
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20647
BRD-K48019220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77792
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15834
HEC116	DepMap CRISPR Gene Dependency	1.0	2.93484
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38064
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03084
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06352
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07304
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46639
eucatropine-2556	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02841
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1688
metacycline-4143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluphenazine-494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28133
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20817
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831324
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879089
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11672894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39586
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13228
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47622
Cornified envelope formation	KEGG Pathways 2026	1.0	null
chlorogenic acid-4024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12658
BRD-K57572982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14937
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bumetanide-5542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0596
BRD-K72932441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05208
bicellular tight junction	GO Cellular Component Annotations 2023	1.0	null
BRD-K95768123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67941
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48553
minocycline-5077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4512
fluspirilene-5008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5433
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87277
BRD-K34005205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24688
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
prasterone-6474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888466
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.77931
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4943-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polydipsia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K45142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24316
BRD-K91021522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08233
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983094
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02189
TRIM	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45248
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18613
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.41918
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	3.92957
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54299
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14661
pramocaine-6054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12616
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1839
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21073
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051673
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06293
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07438
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0085
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20632
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74014
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26368
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42345
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29536
tight junction	GO Cellular Component Annotations 2025	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9456
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08171
abnormal kidney physiology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-A26583774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16484
Lung squamous cell carcinoma_LUSC_TCGA-22-4604-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30465
Pallidum, ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12542
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23008
estrone-6448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9291
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14408
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.7475
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18281
haloperidol-6203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00081
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32647
heliotrine-6035	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6982
antazoline-6775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.641
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21578
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2208
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01237
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18574
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
troglitazone-462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.206248
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL11	DepMap CRISPR Gene Dependency	1.0	2.02243
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15599
BRD-K41192699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10546
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05117
PNU-0230031-3629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836412
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82968
desoxycortone-6476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833591
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37618
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7164
BRD-K42663371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07959
BRD-K59239976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29228
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2072
MEG-01	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
ifosfamide-5805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7817
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1298
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02271
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0534
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86957
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04904
occluding junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	16.6654
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31426
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982371
COLO320	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2773
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3457
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51535
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13365
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
NCIH292	DepMap CRISPR Gene Dependency	1.0	4.13497
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0791
terguride-6459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36147
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24236
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
pizotifen-5072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	1.4599
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28569
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04757670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00295
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03042
methotrexate-5419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21976
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0025
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.38299
apical junction complex	GO Cellular Component Annotations 2025	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kawain-2299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20102
BRD-K30377659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05112
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.03944
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.21156
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.50801
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
BRD-K42392619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29599
BRD-K93223696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00118
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1846
econazole-7427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9208
increased circulating bicarbonate level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37071
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891216
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.435
CRCGN017_MCF10A.TP53.M_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06124
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948577
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45967
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	6.89525
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07718
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96967
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2025	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02841
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.072
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5245
testosterone-5636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1768
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1341	CCLE Cell Line Gene Expression Profiles	1.0	1.37043
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05134
CD24_Reduced expression_GDS1392_93_human_Bone Marrow	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.551838
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06809
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36472
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.259
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51417
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32943
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9264
tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.835056
nilutamide-6481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28419
fourtransmembrane	GeneRIF Biological Term Annotations	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874721
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68387
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856809
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46598
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12513721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2995
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6721
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.71992
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.495
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70015
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.976
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.29646
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3374
AG-013608-5904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1889
BRD-K53617314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15336
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3312
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64681
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37176
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0056
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28411
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3177
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844404
BRD-K03995743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87361
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94258
decreased defecation amount	MGI Mouse Phenotype Associations 2023	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3328
procaine-5430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987166
BRD-K31589685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11716
BRD-K11016405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0116
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76156
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A97N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32958
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01285
HEL	CCLE Cell Line Gene CNV Profiles	1.0	2.21846
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	2.38873
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8912
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60032
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07079
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14267
BRD-K83297764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0138
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993106
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0565
0179445-0000-4289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7364
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13153
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06083
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6383
Hepatitis C	KEGG Pathways 2026	1.0	null
CRCGN011_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0124
BRD-K25177502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19402
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5906
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893355
imatinib-483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22956
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5234
KYSE70	CCLE Cell Line Gene Expression Profiles	1.0	2.21443
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31623
MYC	ENCODE Transcription Factor Targets	1.0	null
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34623
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73081
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97963
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41576
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11007
fluspirilene-6463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60948317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74867
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88746
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79173
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.35763
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17272
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20893
Periplasmic flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75293
BRD-K18864235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72983
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70642
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87548
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17989
Urinary bladder epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
tonzonium bromide-6457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12271646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15232
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93953
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868518
BRD-K96505704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25508
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rolipram-6449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09703
bicellular tight junction	GO Cellular Component Annotations 2025	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.851
BRD-K69661816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00102
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42484
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99535
BRD-K12099407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24365
BRD-K64742599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15494
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24238
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08021
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A25243629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10362
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06867
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30471
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prazosin-826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839181
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.76745
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07581
abnormal renal glomerular capsule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52918
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35835
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23298
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962095
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFM-223	GDSC Cell Line Gene Expression Profiles	-1.0	-2.78164
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33334
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63546
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46933
bupropion-3180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79619
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0929
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
claudin	GeneRIF Biological Term Annotations	1.0	null
postnatal growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11007
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96182
cellular_component	GO Cellular Component Annotations 2015	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22956
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53919
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithelial to mesenchymal transition in colorectal cancer	WikiPathways Pathways 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62504
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947667
BRD-A95239561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86255
ergocalciferol-6746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5421
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97731
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.75129
occluding junction	GO Cellular Component Annotations 2015	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64521
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00361
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hypertrophy	CTD Gene-Disease Associations	1.0	1.12564
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15704
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41654
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14999
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02128
tolbutamide-4362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
wx1722wx2cx810c	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
etiocholanolone-6060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alfadolone-6506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BL-41	GDSC Cell Line Gene Expression Profiles	1.0	1.45895
cldn17	GeneRIF Biological Term Annotations	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60802
staurosporine-508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7474-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K43086600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45017
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12666
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42345
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26636
finasteride-6062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.4304
RT11284	CCLE Cell Line Gene CNV Profiles	1.0	1.38252
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53145
BRD-K25596713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68781
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8547
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NF-Y	MotifMap Predicted Transcription Factor Targets	1.0	null
germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492182
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29486
BRD-K84601599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17031
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.738
cell junction assembly	GO Biological Process Annotations 2015	1.0	null
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41961
BRD-K88321606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26709
BRD-K79437066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24498
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55584
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83025
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1652
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90496
fusidic acid-6754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell-cell junction	GO Cellular Component Annotations 2025	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5799
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64521
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48714
BRD-K29039402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25166
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5982
MDCK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
probenecid-4771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21221
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967086
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03783
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bicellular tight junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
promethazine-6477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17107214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34818
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924238
BRD-K77643021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17259
Pseudopodium membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.788
sirolimus-402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898985
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07246
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76318
NCI-H2171	GDSC Cell Line Gene Expression Profiles	1.0	1.53708
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.75306
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53312
neostigmine bromide-2432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82904
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56974
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64574
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
BRD-A77907596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13691
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02734
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28311
dextromethorphan-5401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06253
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08383
Cell-Cell communication	Reactome Pathways 2014	1.0	null
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30471
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30837
BRD-K75869095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35923
meclofenoxate-3605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Substantia innominata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29433
dapsone-5078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tight junction	KEGG Pathways 2026	1.0	null
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28939
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03997
LY-294002-361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6852
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K44834268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1187
BRD-K68984041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05078
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6651
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75637705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6735
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST486	CCLE Cell Line Gene Expression Profiles	1.0	1.71535
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
domperidone-4640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K65313110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14234
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39225
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48263
Liver carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
methocarbamol-2111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14513
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11966
proxymetacaine-5433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69527
bergenin-5870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87990170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27991
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04937
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48205
tretinoin-384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998047
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8128
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.07585
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01196
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.347
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2489
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14192
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827819
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62037
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4589
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sulfachlorpyridazine-6046	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079823
STAT3	ENCODE Transcription Factor Targets	1.0	null
chlorpromazine-5577	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04877855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0658
BRD-K79887735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79665
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45318
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5969
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47649
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8254
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.979133
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01686
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	1.42878
NFIA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5593
Response to statin therapy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50737
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17269
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.83396
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5946
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24078
Esophageal squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08944
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07166
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34705
trichostatin A-4344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19575
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51271
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14825
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73146
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83116
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.64932
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40331
acetylsalicylic acid-6164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25847
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62064
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50402
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.43792
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2023	1.0	null
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32576
BRD-K26682747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02647
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4789
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30322
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76489
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7037
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0424
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07214
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.3227
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054456
BRD-K87418410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00796
monorden-484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92155
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03966
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86957
ECC4	DepMap CRISPR Gene Dependency	1.0	2.12156
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06634
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76447
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6398
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.572
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9344
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17988
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.88316
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K49029187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11127
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69391
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54979
BRD-K13798725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24927
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972658
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.59924
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLCPRF5	CCLE Cell Line Gene CNV Profiles	1.0	1.39246
TRIFLUPERIDOL-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90701
cellular process	GO Biological Process Annotations 2015	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43425
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54871
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.2801
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.90475
paracellular transport	GO Biological Process Annotations 2025	1.0	null
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6408-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19002
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.8546
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57289
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69613
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22844
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.55468
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16066
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.24118
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A702-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	11.5086