association	dataset	threshold value	standardized value
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62137
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824122
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849975
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849975
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3697
NUPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43167
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44698
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99203
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68381
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0006
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03484
EZH2	ENCODE Transcription Factor Targets	1.0	null
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15984
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53388
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01797
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97694
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27342
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33562
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37152
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42989
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84655
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2594
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10898
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0737
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15799
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858707
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55568
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09595
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52778
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6446
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0178
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09129
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15594
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67315
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14046
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22852
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26847
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04078
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF-29-QU48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20558
STAT3	ENCODE Transcription Factor Targets	1.0	null
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07479
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98112
POLR2A	ENCODE Transcription Factor Targets	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24833
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00954
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.49203
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17093
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.35445
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23017
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44702
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1279
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55285
ALKBH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09161
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905893
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050238
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.08474
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10984
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5146
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47656
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73639
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14928
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.377
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87733
ATF7IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83777
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6244
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94237
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29065
PMC11370252-12864_2024_10619_MOESM2_ESM.xlsx-EMP_AA-Gene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35749
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55285
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64042
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0784
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34744
U2904	DepMap CRISPR Gene Dependency	1.0	4.98303
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92183
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03408
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36284
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1743
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24548
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986431
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4621
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21875
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23855
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19773
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36099
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0574
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849975
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3419
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11055
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849975
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58745
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47012
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
vh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40927
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1694
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.795
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09781
HKA1	DepMap CRISPR Gene Dependency	1.0	2.53609
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.247854
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36916
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4405
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.13913
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5244
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08648
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14603
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983259
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99235
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93463
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1092
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918271
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1165
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45407
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71788
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24331
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
Colipase	InterPro Predicted Protein Domain Annotations	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11022
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6231
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05659
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1043
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837847
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.00448
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26807
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.18168
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.49585
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59665
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827368
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7991
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34534
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12847
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00353
TENT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44279
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.59925
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1092
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043906
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34295
CHLA57	DepMap CRISPR Gene Dependency	1.0	4.08937
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26701
GID8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37286
COLO679	DepMap CRISPR Gene Dependency	1.0	3.07586
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58814
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8434
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9562
PGA1	DepMap CRISPR Gene Dependency	1.0	3.34053
OPM2	DepMap CRISPR Gene Dependency	1.0	4.11017
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91228
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65355
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39395
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42947
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877565
SNU387	DepMap CRISPR Gene Dependency	1.0	2.00335
HT-22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88963
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15287
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9811
NR3C1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27345
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08361
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.168
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.527
RNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90538
CDR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33709
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66044
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.33745
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22738
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
brain	GTEx Tissue Gene Expression Profiles	1.0	0.93163
Thoracic leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.482
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21655
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6085
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50411
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846912
MERO83	DepMap CRISPR Gene Dependency	1.0	3.61726
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49538
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40462
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7856
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80582
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.77232
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
MAP3K21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64453
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916728
Foot sole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94134
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78836
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30254
ROS50	DepMap CRISPR Gene Dependency	1.0	3.14889
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6075
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68953
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14257
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83334
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36233
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	3.95241
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55903
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2856
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65417
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02961
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951658
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20179
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
breast	GTEx Tissue Gene Expression Profiles	1.0	1.19833
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8985
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29371
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43824
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71035
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48069
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35372
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22314
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5041
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9396
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.55749
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79067
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31473
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55654
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04734
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56599
MDAMB361	DepMap CRISPR Gene Dependency	1.0	7.01541
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.462
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851504
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45097
NACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7458
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	3.27962
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050294
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24433
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81874
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08038
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5589
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1_T47D_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84568
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24873
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46311
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35015
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6499
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29836
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1092
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042421
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41724
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23636
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64943
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91655
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6499
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4384
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z4-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69141
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.079
Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6732
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09937
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00146
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92183
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34949
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5769
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59223
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7595
BATF	ENCODE Transcription Factor Targets	1.0	null
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74023
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45151
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42474
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09155
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966064
enzyme activator activity	GO Molecular Function Annotations 2015	1.0	null
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75983
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.77834
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.35521
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.168
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
NCO2	DepMap CRISPR Gene Dependency	1.0	2.11502
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.36451
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65771
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866569
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.083
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61272
nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.22385
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7687
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6983
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12844
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34421
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44896
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
RELA	ENCODE Transcription Factor Targets	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39437
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52737
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52489
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40147
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0697
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0475
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21538
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0858
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.18376
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59685
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9192
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05866
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2928
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60566
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.26197
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32226
Head and Neck squamous cell carcinoma_HNSC_TCGA-HL-7533-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5983
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53056
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0929
CBX2	ENCODE Transcription Factor Targets	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91224
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2001
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054598
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92463
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6088
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9946
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2905
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H522	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A762-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05276
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82601
Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5031
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8979
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28879
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62834
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29496
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041854
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20037
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2116
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75332
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1003
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2681
U937	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51561
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00782
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.544
Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05282
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92059
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53646
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0332
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6252
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89749
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22066
BIN67	DepMap CRISPR Gene Dependency	1.0	3.7324
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15854
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887958
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68503
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519567
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75291
RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66838
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88272
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4948
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09917
extracellular region	GO Cellular Component Annotations 2015	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22643
CA46	CCLE Cell Line Gene CNV Profiles	-1.0	-3.06011
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.421
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53144
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.168
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1092
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830775
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41878
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57093
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.382
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64051
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24818
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9692
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23586
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49057
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290758
FOXA1	ENCODE Transcription Factor Targets	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983259
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52272
NR3C1	ENCODE Transcription Factor Targets	1.0	null
NAMALWA	DepMap CRISPR Gene Dependency	1.0	4.0721
HUH28	CCLE Cell Line Gene CNV Profiles	1.0	1.78259
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9196
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33035
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5397
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3008
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12392
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8059
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8635
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31084
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6815
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24769
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72125
ZNF367	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37601
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46785
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01505
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041517
Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81589
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832712
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.0666
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.768
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31651
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57021
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.267
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99012
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5388
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5995
ESR1_T47D_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874999
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86524
CHK1_KD_GSE54268_665_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TCF12_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13599
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26866
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59888
SKNFI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19779
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598871
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01827
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24004
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77545
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5719
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52891
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4216
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15547
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08531
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10087
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CY-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65193
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0948
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0834
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81597
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953249
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.16428
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.28653
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05962
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.58056
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07515
p95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
DIFI	DepMap CRISPR Gene Dependency	1.0	3.55275
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24673
TEN	DepMap CRISPR Gene Dependency	1.0	3.78622
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91539
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14395
HEC59	DepMap CRISPR Gene Dependency	1.0	3.91715
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04076
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974961
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.079
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3909
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02759
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95365
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983259
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3451
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1184
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21356
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.43469
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16433
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06488
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09168
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3975
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919368
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ICC8	DepMap CRISPR Gene Dependency	1.0	2.27401
FTC238	CCLE Cell Line Gene CNV Profiles	1.0	2.08395
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50063
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3677
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13933
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22318
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9118
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55066
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4848
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06999
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42384
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37287
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02492
CCNYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34759
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57594
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14296
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17237
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55334
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55939
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41684
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5104
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28349
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918271
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19919
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937051
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34614
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57233
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05685
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55947
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34446
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.273734
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06595
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.11404
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893185
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU449	DepMap CRISPR Gene Dependency	1.0	3.02426
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26832
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8394
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20115
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09393
KDM5B	ENCODE Transcription Factor Targets	1.0	null
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65873
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26747
digestion	GO Biological Process Annotations 2015	1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27182
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.36451
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1561
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16122
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31871
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9917
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21504
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49506
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21558
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00789
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79492
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27342
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868512
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56798
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40298
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3336
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2514
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043996
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44025
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4432
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
beta-catenin-TCF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22525
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41878
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25742
JADE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.95961
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3033
GATA3	ENCODE Transcription Factor Targets	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2634
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.91211
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878868
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36079
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053366
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6218
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65684
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3713
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42667
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8821
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837851
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5136
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925335
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1092
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39562
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30862
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8052
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19358
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78645
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66235
pancreas	GTEx Tissue Gene Expression Profiles	1.0	2.18987
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6589
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24202
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.96604
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24381
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9685
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	2.03469
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3008
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.80844
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06268
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.168
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931123
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943343
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61391
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89032
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81878
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
HEC251	DepMap CRISPR Gene Dependency	1.0	2.14252
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24528
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17286
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20386
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7199
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.10037
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8459
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11022
SU8686	DepMap CRISPR Gene Dependency	1.0	2.34005
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.945087
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0992
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.08674
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975418
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2117
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69903
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30805
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3809
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56868
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1331
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37496
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61602
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
PMC5105060__F9	PFOCR Pathway Figure Associations 2024	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5647
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35545
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31397
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
HDAC2	ENCODE Transcription Factor Targets	1.0	null
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54526
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	7.81429
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5768
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7507
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63318
21NT	DepMap CRISPR Gene Dependency	1.0	3.19167
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09819
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84612
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54912
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00198
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973037
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27516
CREBBP	ENCODE Transcription Factor Targets	1.0	null
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00516
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898215
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81F-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76153
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02541
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0489
GB-01-UN23_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244368
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60204
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6384
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27342
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00022
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878511
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20674
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01979
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873997
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50783
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.60941
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043616
F5	DepMap CRISPR Gene Dependency	1.0	4.58691
Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39169
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71025
UMUC13	DepMap CRISPR Gene Dependency	1.0	4.83982
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0258
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.079
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30254
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77889
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.138
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34931
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57249
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51731
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32832
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4361
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55221
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26628
PMC5105060__F9	PFOCR Pathway Figure Associations 2023	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77792
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4827
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13496
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30164
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	2.36432
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06567
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28024
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050007
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22745
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3164
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS729	DepMap CRISPR Gene Dependency	1.0	4.87766
TTC642	DepMap CRISPR Gene Dependency	1.0	3.0134
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24818
ESR1	ENCODE Transcription Factor Targets	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8448
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	3.07552
KE-41-JG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305545
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06334
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52728
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32188
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19941
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4323
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.35096
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-40-CD57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322384
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80672
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3366
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13255
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831711
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983259
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828127
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984271
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12359
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07562
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15283
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79447
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31311
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39904
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1118
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6641
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33615
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02947
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53765
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999412
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41687
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23663
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89653
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93588
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17803
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09267
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3907
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83802
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17433
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14645
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07921
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837652
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
TE6	DepMap CRISPR Gene Dependency	1.0	2.49876
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.168
epididymis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0937
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8626
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15649
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25905
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27073
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18285
FMNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38752
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-2.55272
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25417
NR2F2	ENCODE Transcription Factor Targets	1.0	null
NP2	DepMap CRISPR Gene Dependency	1.0	2.87363
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0337
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLR20	DepMap CRISPR Gene Dependency	1.0	2.35283
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25731
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869453
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43336
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15547
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00914
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32327
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38055
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39862
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41096
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9742
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5156
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2611
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880548
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043335
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.70439
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6891
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27149
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.588794
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8053
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66715
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67408
NCIH1836	DepMap CRISPR Gene Dependency	1.0	6.95211
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8987
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35276
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	4.3421
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7526
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3812
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61776
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.73616
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1936
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66456
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.247
HG3	DepMap CRISPR Gene Dependency	1.0	4.95076
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2015
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60914
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9484
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31875
TUR	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928156
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8288
FOS	ENCODE Transcription Factor Targets	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.976387
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918271
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29508
EB-09-JJ93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29333
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00669
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59753
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04395
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2758
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.33747
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61335
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
JMURTK2	DepMap CRISPR Gene Dependency	1.0	2.26226
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82986
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27174
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5627
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80085
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40651
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2445
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30529
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86667
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6042
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94201
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28992
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74283
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43213
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07778
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6624
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27201
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.76899
COLO205	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33819
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03185
Hippocampal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7189
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92168
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU626	DepMap CRISPR Gene Dependency	1.0	3.71861
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47459
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03779
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48608
Epididymis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9063
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3532
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63599
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
NCIH522	DepMap CRISPR Gene Dependency	1.0	2.78694
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3497
EOL1	DepMap CRISPR Gene Dependency	1.0	2.44856
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52871
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96728
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60378
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050295
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20203
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90048
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938207
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.57687
JHUEM1	DepMap CRISPR Gene Dependency	1.0	4.19534
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
TCF12_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05224
KYO1	DepMap CRISPR Gene Dependency	1.0	5.77105
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8053
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5407
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869955
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
ESR1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5014
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.817
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03696
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38622
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39928
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40562
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19832
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	2.59921
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95572
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07172
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20156
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2285
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44089
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849975
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56592
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79801
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27907
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44918
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5794
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905893
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877565
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7158
S462	DepMap CRISPR Gene Dependency	1.0	4.04371
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19005
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83214
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.823967
BT12	DepMap CRISPR Gene Dependency	1.0	11.9919
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4421
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15988
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85325
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9629
ESR1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9969
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0001
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9606
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29196
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.45309
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Epilepsy with generalized tonic-clonic seizures	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71501
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01019
ESR1_T47D_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59701
biological_process	GO Biological Process Annotations 2015	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04251
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59984
nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.445275
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00478
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
ESR1_T47D_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
EP300	ENCODE Transcription Factor Targets	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8739
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24818
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29081
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30169
lung	GTEx Tissue Gene Expression Profiles	-1.0	-1.23899
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47818
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21406
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2939
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962379
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
H2AC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47255
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.61456
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01825
UQCRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9447
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3366
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1387
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98987
TCF12	ENCODE Transcription Factor Targets	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042195
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24818
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04457
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21046
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57249
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.90666
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2657
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5566
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27823
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.05391
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6793
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34116
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.7233
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.608
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-80-5607-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5819
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76821
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76665
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86489
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4691
Lung adenocarcinoma_LUAD_TCGA-69-7760-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83276
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944783
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.292
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26784
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24181
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0806
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938207
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3176
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90425
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03728
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06333
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82059
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49464
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5715
MEC1	DepMap CRISPR Gene Dependency	1.0	2.68765
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984271
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78783
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02038
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45186
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877565
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52585
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09009
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FGFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39309
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86643
MYC	ENCODE Transcription Factor Targets	1.0	null
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952025
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2662
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr6_35797677_T_TTA_b38	GTEx eQTL 2025	1.0	1.55675
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49692
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4861
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04413
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.40411