association	dataset	threshold value	standardized value
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08426
PHYKPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79277
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46433
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18631
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56199
Autosomal recessive nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	2.11573
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z4-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.44719
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58352
Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.58891
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2529
Stereocilium bundle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911903
PPARG	ChEA Transcription Factor Targets	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859697
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08055
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3535
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00878
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88835
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
Kna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Inner ear disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
JM1	DepMap CRISPR Gene Dependency	1.0	3.55869
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Clarin	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02962
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10902
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03996
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97914
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
decreased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
MAFK	ENCODE Transcription Factor Targets	1.0	null
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60408
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47414
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29875
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958371
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.16933
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71949
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24981
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51135
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.01264
Heterocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
B3GNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59135
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5981_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.44745
lung disease	GWASdb SNP-Disease Associations	1.0	0.426044
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846453
FOS	ENCODE Transcription Factor Targets	1.0	null
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.59307
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12877
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968577
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.13121
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51478
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSU72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18266
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WQ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT11284	CCLE Cell Line Gene CNV Profiles	1.0	1.54752
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39054
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46194
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20856
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16449
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77057
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Stereocilium tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.09
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29021
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.136
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06686
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76304
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
Autosomal dominant auditory neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.05
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
LUDLU1	DepMap CRISPR Gene Dependency	1.0	3.0815
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881413
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90642
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1126
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2816
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01512
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
Autosomal dominant nonsyndromic deafness 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
SNU1105	DepMap CRISPR Gene Dependency	1.0	3.38377
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8421
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32446
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96176
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.21727
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4246
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873965
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24693
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29426
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.59545
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58344
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41266
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68542
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45226
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68244
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969416
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21706
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03014
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5XZ-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948274
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873965
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0962
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29934
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GI1	DepMap CRISPR Gene Dependency	1.0	4.31323
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25892
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1713
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38236
cellular component maintenance	GO Biological Process Annotations 2025	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54637
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LTF	MotifMap Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00691
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86602
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65139
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5834
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72027
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62732
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35934
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45874
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8216
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Autosomal recessive nonsyndromic deafness 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.067
TST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67769
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02962
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Psoas major	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
MYC	ENCODE Transcription Factor Targets	1.0	null
Posterior fossa meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890369
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V6-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13332
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0717
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59806
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.3599
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
short insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903044
leukopenia	GWASdb SNP-Disease Associations	1.0	0.766444
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69418
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.981
Autosomal recessive nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.816
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5949
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34928
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.41382
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.6869
vagina	GTEx Tissue Gene Expression Profiles	-1.0	-1.01264
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836755
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25671
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10557
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12803
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.8984
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
bronchial disease	GWASdb SNP-Disease Associations	1.0	1.73614
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34775
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01752
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS123	DepMap CRISPR Gene Dependency	1.0	2.51655
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25041
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21889
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910917
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.01264
MFSD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90144
decreased bone mineral density	IMPC Knockout Mouse Phenotypes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55051
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09957
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4879
SUP-B8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49627
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09202
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.05
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37332
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC251	DepMap CRISPR Gene Dependency	1.0	2.51801
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3432
HCC1395	DepMap CRISPR Gene Dependency	1.0	4.30778
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	1.73614
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2567
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76149
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22048
auditory receptor cell morphogenesis	GO Biological Process Annotations 2023	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.047
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
nonsyndromic hearing loss	MGI Mouse Phenotype Associations 2023	1.0	null
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.3273
RNF2	ENCODE Transcription Factor Targets	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.01264
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
MBD4	ENCODE Transcription Factor Targets	1.0	null
cellular component maintenance	GO Biological Process Annotations 2023	1.0	null
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.5572
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03621
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38529
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22048
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50475
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09716
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Airway fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
decreased startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23649
BT-549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 109	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.045
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.21257
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.91319
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
NELFE	ENCODE Transcription Factor Targets	1.0	null
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01869
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08818
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14841
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36633
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72687
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69054
HUH7	DepMap CRISPR Gene Dependency	1.0	14.1951
increased or absent threshold for auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65278
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
SNU1544	DepMap CRISPR Gene Dependency	1.0	2.55675
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89029
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51008
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25223
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
C99	DepMap CRISPR Gene Dependency	1.0	2.69989
Autosomal recessive nonsyndromic deafness 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54528
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.75454
MXI1	ENCODE Transcription Factor Targets	1.0	null
Superior semicircular canal dehiscence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.49915
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.002
Lung adenocarcinoma_LUAD_TCGA-44-6776-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14397
MAX	ENCODE Transcription Factor Targets	1.0	null
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.426044
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.03641
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17438
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45393
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20374
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993708
CHD1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934216
lymphoma	GWASdb SNP-Disease Associations	1.0	1.73614
Cluster of actin-based cell projections	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.43647
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960906
brain	GTEx Tissue Gene Expression Profiles	1.0	1.30391
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17474
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9902
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69698
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84761
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09699
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89971
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U343	CCLE Cell Line Gene CNV Profiles	1.0	1.77403
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837045
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.384
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81688
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased bone mineral content	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01247
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38635
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.7567
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19544
TFB2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82784
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.363
Klippel-Feil syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
TPST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56041
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.065
Landau-Kleffner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
HNF4A	ENCODE Transcription Factor Targets	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.437
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.534258
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.766444
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10576
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37921
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4906
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.404941
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1016-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14764
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905929
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47228
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8276
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5066
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44264
PMC12229934-ab-24-0809-Supplementary-2.pdf-1-ZNF750_ZNF750	Rummagene Transcription Factor Associations 2026	1.0	null
BIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42987
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.11641
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29323
CEBPB	ENCODE Transcription Factor Targets	1.0	null
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89965
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04608
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873965
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84452
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97211
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
Usher syndrome type 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.842
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2472
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948362
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88041
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8629
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974739
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	3.55316
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875459
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11862
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREBZF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65516
LPS510	DepMap CRISPR Gene Dependency	1.0	2.08989
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7253
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5663
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QZ-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18465
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2149
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	1.42994
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961786
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19094
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902065
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7711
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25837
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.088
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.087222
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	2.07104
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.956912
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86427
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7343
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.897798
DU-4475	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.11641
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88007
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.68
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63888
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77889
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64544
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.65387
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859697
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15726
Autosomal dominant nonsyndromic deafness 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07928
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.041224
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60217
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.409
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6131
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958371
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4719
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80302
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.61083
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.23
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10903
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32422
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59561
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828193
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72288
SUSA	DepMap CRISPR Gene Dependency	1.0	3.38009
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES4	DepMap CRISPR Gene Dependency	1.0	2.00371
Sensorineural hearing loss	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75232
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.455
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77057
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84806
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50748
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7383-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84269
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
Skull base meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13654
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48995
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64367
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43987
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44095
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96792
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2132
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1667
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4	ChEA Transcription Factor Targets	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.363
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858665
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
abnormal distortion product otoacoustic emission	MGI Mouse Phenotype Associations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91639
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18004
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
Branchiootic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18093
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A780-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cochlear inner hair cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67487
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26843
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myosin XV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02962
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
Hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43833
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47477
Brain Lower Grade Glioma_LGG_TCGA-FG-7638-01B-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4146
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59268
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08055
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4694-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.845
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46301
membrane part	GO Cellular Component Annotations 2015	1.0	null
SW900	CCLE Cell Line Gene CNV Profiles	1.0	2.32897
CNNM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88842
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59689
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08584
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09699
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32867
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892417
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5487
Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of sound	GO Biological Process Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.41546
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9865
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860595
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5315
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29463
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.51256
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19697
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23485
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59958
Autosomal recessive nonsyndromic deafness 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16449
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.404941
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.6001
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
all	GWASdb SNP-Phenotype Associations	1.0	0.041013
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.404941
MON	DepMap CRISPR Gene Dependency	1.0	3.45341
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
TTC549	DepMap CRISPR Gene Dependency	1.0	4.44049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80163
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0838
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92851
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.91319
ES5	DepMap CRISPR Gene Dependency	1.0	2.29406
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1196
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29504
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873965
ZNF439	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56004
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
abnormal inner ear vestibule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive nonsyndromic deafness 77	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5731
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57627
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6219
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100387_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.62832
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89873
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	1.62842
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.035
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Melnick-Needles syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958371
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.26
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958371
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929136
USF1	ENCODE Transcription Factor Targets	1.0	null
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32272
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
KBG syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.20428
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904719
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01509
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97062
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.40232
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46166
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23515
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	0.91319
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91196
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890359
Age-related hearing impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.03979
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7748-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.411
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83583
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85144
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34665
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44094
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908744
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35538
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.942687
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19421
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3704
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958371
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88474
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55378
Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9747
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30733
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16643
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50988
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.116733
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	8.0737
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.981
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
precentral gyrus, left, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870074
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.552
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.41847
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.88504
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
Powassan encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
Lymphocyte Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2921
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1169
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
Hypomyelinating leukodystrophy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Autosomal recessive nonsyndromic deafness 79	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.76309
decreased bone mineral content	MGI Mouse Phenotype Associations 2023	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70372
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985537
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
WM3772F	DepMap CRISPR Gene Dependency	1.0	4.03228
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59949
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934239
MAP3K9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62736
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01247
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A898-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A7UZ-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
auditory receptor cell morphogenesis	GO Biological Process Annotations 2025	1.0	null
TMEM63B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6275
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7295
GATA1	ENCODE Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FOXA1	ENCODE Transcription Factor Targets	1.0	null
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9438
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0325
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	0.912131
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2125
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48134
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
CAMKK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58892
ZBTB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88101
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843717
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.893
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79752
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive nonsyndromic deafness 115	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.211
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.44473
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28122
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
Autosomal recessive nonsyndromic deafness 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.036
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.91319
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65388
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
496100301_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.0039
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukemia	GWASdb SNP-Disease Associations	1.0	1.73614
Kaufman oculocerebrofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34461
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.25826
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Usher syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.738
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65478
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.25
JUND	ENCODE Transcription Factor Targets	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
HCC1419	DepMap CRISPR Gene Dependency	1.0	4.17004
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
HOS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48873
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88385
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25041
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.160072
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02421
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.27332
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84125
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45343
CFPAC1	CCLE Cell Line Gene CNV Profiles	1.0	1.4294
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16118
auditory receptor cell stereocilium organization	GO Biological Process Annotations 2025	1.0	null
Autosomal dominant nonsyndromic deafness 65	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5206
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94123
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.24645
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82362
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83296
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.147751
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.46794
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16294
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95527
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2007
LU165	DepMap CRISPR Gene Dependency	1.0	2.33138
increased vertical activity	MGI Mouse Phenotype Associations 2023	1.0	null
EXOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47601
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00931
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41646
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30445
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.47781
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
21NT	DepMap CRISPR Gene Dependency	1.0	5.3613
BICR78	DepMap CRISPR Gene Dependency	1.0	2.43385
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7986
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46002
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924657
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58807
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3827
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854924
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75638
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05847
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	2.07183
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.798326
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45931
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859697
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32483
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.91319
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.91319
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51326
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61152
NCIH358	CCLE Cell Line Gene CNV Profiles	1.0	1.58595
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72391
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.6083
inner ear receptor cell stereocilium organization	GO Biological Process Annotations 2023	1.0	null
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51952
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-3.09555
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6342-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.13
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00585
Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4945-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85952
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04284
Autosomal dominant nonsyndromic deafness 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846131
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15972
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840124
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07251
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0837
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08069
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888036
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976315
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59639
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45047
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8257
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50634
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
Petroclival meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71107
increased vertical activity	IMPC Knockout Mouse Phenotypes	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7687
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skull base cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54866
MAZ	ENCODE Transcription Factor Targets	1.0	null
stereocilium maintenance	GO Biological Process Annotations 2025	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24961
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.210966
CMK115	DepMap CRISPR Gene Dependency	1.0	4.13543
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924015
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849569
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
HOS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40954
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989652
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62961
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.99
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52835
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7687
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7158-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner ear receptor cell stereocilium organization	GO Biological Process Annotations 2025	1.0	null
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
Lung adenocarcinoma_LUAD_TCGA-50-5942-01A-21R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76202
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.91319
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08979
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
sensory perception of sound	GO Biological Process Annotations 2025	1.0	null
Frontometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40836
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90895
CBX8	ENCODE Transcription Factor Targets	1.0	null
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1062
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09163
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952394
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28047
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63944
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52011
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.30933
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6109
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.68069
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
MYBL2	ENCODE Transcription Factor Targets	1.0	null
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43942
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.93718
asthma	GWASdb SNP-Disease Associations	1.0	1.73614
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.91319
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86471
increased total body fat amount	IMPC Knockout Mouse Phenotypes	1.0	null
increased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	3.11617
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69936
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58014
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-7332-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899357
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74926
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7962
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26093
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50583
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97589
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925318
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95562
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9477
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6904
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70853
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83263
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73527
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66119
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07928
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15659
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.111251
SP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61801
KDM5B	ENCODE Transcription Factor Targets	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16643
Autosomal recessive nonsyndromic deafness 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859697
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	2.5501
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61581
decreased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9007
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50219
GPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64885
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3387
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
lingual gyrus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05549
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.23201
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
USF2	ENCODE Transcription Factor Targets	1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07511
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.705
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4374
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974739
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85734
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24598
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
MC-IXC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.56172
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826339
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC6	DepMap CRISPR Gene Dependency	1.0	2.24163
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1826
CHK1_KD_GSE54267_671_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMP-22/EMP/MP20/Claudin superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62004
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02417
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888036
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78487
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46792
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.16378
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81294
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2497
ZSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72208
AGS	DepMap CRISPR Gene Dependency	1.0	2.32568
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.489
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68978
abnormal hair cell mechanoelectric transduction	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5175
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.077
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
lung	HPA Tissue Protein Expression Profiles	1.0	0.91319
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52638
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5907
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.964442
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9943
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26761
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71659
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
Xia-Gibbs Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.547
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8938
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
immune system disease	GWASdb SNP-Disease Associations	1.0	0.140893
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.374
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00816
ZNF843	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1833
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
stomach	HPA Tissue Protein Expression Profiles	1.0	0.91319
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61598
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14634
D502MG	DepMap CRISPR Gene Dependency	1.0	6.35136
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10557
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34538
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02661
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4661
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.233346
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
TASK1	DepMap CRISPR Gene Dependency	1.0	2.70268
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.082987
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0167
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
RBE	DepMap CRISPR Gene Dependency	1.0	4.50095
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1936
sensory perception of mechanical stimulus	GO Biological Process Annotations 2023	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64099
DNAJB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99789
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31365
deafness	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
decreased bone mineral density	MGI Mouse Phenotype Associations 2023	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42932
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85229
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46339
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Swr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3754
TTC642	DepMap CRISPR Gene Dependency	1.0	2.40351
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5733
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43573
TSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22166
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.345
Autosomal recessive nonsyndromic deafness 32	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7915
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03014
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.175727
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
Autosomal recessive nonsyndromic deafness 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.041
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24562
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886566
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91298
Nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969416
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphopenia	GWASdb SNP-Disease Associations	1.0	1.73614
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
SP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06276
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.19477
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.02688
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3661
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5409
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25704
D458	DepMap CRISPR Gene Dependency	1.0	4.84568
sensory perception of mechanical stimulus	GO Biological Process Annotations 2025	1.0	null
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41496
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969416
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4966
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	2.20762
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6096
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44102
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.66908
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5566
697	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42916
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19731
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30625
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.903
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9157
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61581
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33388
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cochlear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
Skull cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
DRAXIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67487
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57718
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41768
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25345
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27213
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16355
lymphoma	GWASdb SNP-Phenotype Associations	1.0	1.62842
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2983
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1259
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38635
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91551
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4926
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06672
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
EW-7	COSMIC Cell Line Gene CNV Profiles	1.0	2.15402
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893653
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3764
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03014
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45626
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.32742
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.585
stereocilium maintenance	GO Biological Process Annotations 2023	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7047
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13798
auditory receptor cell stereocilium organization	GO Biological Process Annotations 2023	1.0	null
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82262
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48042
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0523
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10634
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.233346
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78851