association	dataset	threshold value	standardized value
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	3.73119
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16225
APTO-253_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00984988
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anorexia nervosa	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4066
GCT	CCLE Cell Line Gene Expression Profiles	1.0	1.38463
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19178
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935555
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70921
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44882
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4506
KMRC1	DepMap CRISPR Gene Dependency	1.0	2.10666
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
neoplasm of the genitourinary tract	GWASdb SNP-Phenotype Associations	1.0	0.187866
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01284
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07957
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8951
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0531
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7292
PMC3878729-1471-2148-13-273-S1.xls-Gene_List-Zfp9_ZNF25	Rummagene Transcription Factor Associations 2026	1.0	null
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4275
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09899
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15494
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61113
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.051198
HS274T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62019
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7554
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926842
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7364
abnormality of the uterus	GWASdb SNP-Phenotype Associations	1.0	0.339326
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.101278
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79298
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01142
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33516
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.098463
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07245
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69678
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35856
Optic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7623
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18566
RKO	CCLE Cell Line Gene Expression Profiles	1.0	1.35244
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.049894
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07242
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977343
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4278
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85383
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HS766T	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944058
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870071
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17375
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.047327
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.399
EWSR1	ChEA Transcription Factor Targets	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23676
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.47807
abnormal eye physiology	GWASdb SNP-Phenotype Associations	1.0	0.209089
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	0.53513
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.06006
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959435
female reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.333441
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2416
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6398
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	2.04913
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3928
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32858
Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S3_LMS_SV-Unnamed_2_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.84012
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.61783
RmlC-like jelly roll fold	InterPro Predicted Protein Domain Annotations	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.87039
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.80872
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.679753
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978059
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.296304
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31024
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2875
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65217
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.32186
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4145
Gut microbiota (bacterial taxa, hurdle binary method)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912444
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00761
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KG-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34326
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0959
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16734
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30834
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.24871
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38147
substance dependence	GWASdb SNP-Disease Associations	1.0	0.264065
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913045
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF1AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06233
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8432
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.33803
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6529
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885768
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826755
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20207
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2337
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985358
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S10_DGEA_IKZF1-Supplemental_Table_10_Differentially_expressed_genes_between_IKZF1_and_all_other_subcluster_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.163386
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8631
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847571
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
HEY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4074
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15764
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.50591
JUN	ChEA Transcription Factor Targets	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
Papillary glioneuronal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38552
KMS18	CCLE Cell Line Gene Expression Profiles	1.0	1.47968
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31892
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.60944
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4451
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1502
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4798
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40922
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01617
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34374
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33095
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15569
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6901
kidney	HPA Tissue Protein Expression Profiles	1.0	0.823005
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07126
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872247
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.31738
NUGC3	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44719
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86146
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02655
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62196
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30898
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65714
AR	ChEA Transcription Factor Targets	1.0	null
Normal facial asymmetry (deformation magnitude)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57015
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.81134
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.49202
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33095
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_01_190	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.95224
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978746
Radotinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.013827
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of refraction	GWASdb SNP-Phenotype Associations	1.0	0.375284
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23074
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38962
Congenital sucrase-isomaltase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.499
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71041
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977575
OCIM2	DepMap CRISPR Gene Dependency	1.0	4.43541
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68981
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62529
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64138
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.46943
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46328
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63707
LC1SQ	DepMap CRISPR Gene Dependency	1.0	3.07695
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.0305
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13527
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72618
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15205
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5403
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970465
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.44079
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.86419
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3879
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32419
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0472
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SF767	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42719
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997794
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8175
Peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7034
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905293
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859265
BHY	CCLE Cell Line Gene Expression Profiles	1.0	1.96971
TF1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58746
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.37133
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62658
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42056
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39645
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Corneal ectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06375
NCIH660	CCLE Cell Line Gene CNV Profiles	1.0	1.59496
SNU1197	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02284
LCAM1	DepMap CRISPR Gene Dependency	1.0	3.67113
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.857874
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01418
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29021
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.098341
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5498
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00557
abnormality of the female genitalia	GWASdb SNP-Phenotype Associations	1.0	0.17496
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	12.4019
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.49202
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76215
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59324
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23441
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.53611
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.103407
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03047
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.50501
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01983
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
uterine neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.385704
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.856706
Brain Lower Grade Glioma_LGG_TCGA-DU-7019-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.56513
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29292
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873886
Alcoholism	dbGAP Gene-Trait Associations	1.0	0.170582
testis	HPA Tissue Protein Expression Profiles	1.0	1.49202
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.160023
Cyclic nucleotide-binding-like	InterPro Predicted Protein Domain Annotations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870071
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06824
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.72046
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08201
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0683
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.72885
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.208555
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4199
UDSCC2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13599
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85299
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04286
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935006
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	2.57601
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862227
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32932
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45398
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5623
ZNF217	ChEA Transcription Factor Targets	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16515
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8627
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911531
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2317
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SW403	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
CTNNB1	ChEA Transcription Factor Targets	1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.082901
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9885
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2931
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25675
MDAMB435S	CCLE Cell Line Gene Expression Profiles	1.0	1.41346
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10524
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46176
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56034
mood disorder	GWASdb SNP-Disease Associations	1.0	0.659337
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22391
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38742
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60441
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2348
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46256
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.61681
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
Brain Lower Grade Glioma_LGG_TCGA-DU-7011-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4927
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03186
JJN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1523
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07287
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44727
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56005
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.6085
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58331
Cyclic nucleotide-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66843
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23354
NB13	DepMap CRISPR Gene Dependency	1.0	4.94066
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68029
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7119
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912444
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38718
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971958
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AHR	ChEA Transcription Factor Targets	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947647
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13196
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3226
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4869-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52042
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07666
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66691
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95729
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827438
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AHR-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	1.16174
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5731
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837787
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXB9_HOXB9	Rummagene Transcription Factor Associations 2026	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07029
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.997604
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.02729
REST_01_211	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.85684
arthritis	GWASdb SNP-Disease Associations	1.0	0.238592
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49805
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.253
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA11_HOXA11	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.21394
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64964
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33197
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1456
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07202
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13549
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08781
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3698
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5661
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71632
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825869
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.704784
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960588
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.65441
HCC1419	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
Ralimetinib dimesylate_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0112065
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87404
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7383
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.237731
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76442
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.36935
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.633513
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3618
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.49839
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67398
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48936
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	1.75269
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
D283MED	CCLE Cell Line Gene CNV Profiles	1.0	1.77599
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.751382
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3322
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.149277
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1808
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Mercury levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLC82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87448
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARNT	ChEA Transcription Factor Targets	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	2.1381
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3618
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.945862
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.114647
abnormality of the cornea	GWASdb SNP-Phenotype Associations	1.0	0.255206
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
RPLP0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05561
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12061
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Esophagus adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4257
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.91644
MITF	ChEA Transcription Factor Targets	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.66778
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.82839
all	GWASdb SNP-Phenotype Associations	1.0	0.097774
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	1.01499
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	1.83383
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0079
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58835
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05066
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42278
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58786
VMRCLCD	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28608
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1454
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14434
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80203
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08047
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888774
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827438
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00317
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.02242
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9585
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.923
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04932
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3042
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.116677
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31837
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85553
ATP5F1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02017
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920132
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.114647
GBX2-23144817-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.279195
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.425
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955126
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33778
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
increased corneal curvature	GWASdb SNP-Phenotype Associations	1.0	0.562717
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7901
SKMM2	CCLE Cell Line Gene CNV Profiles	1.0	1.93355
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02391
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5985
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18287
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71114
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.798375
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.56189
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0482
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2021
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.284738
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.121036
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5613
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.073
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51735
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77523
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77771
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54412
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.601604
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9092
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24374
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.65235
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31205
PBX1	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5792-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56178
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56967
PMC4172779-13048_2014_87_MOESM1_ESM.pdf-142-ZNF383_ZNF383	Rummagene Transcription Factor Associations 2026	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5949
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41255
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.384
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Piroxicam_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0123156
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7649-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.97577
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07218
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.456449
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935006
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8143
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51832
MFE280	DepMap CRISPR Gene Dependency	1.0	2.14776
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9039
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48735
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3405
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61215
SUM52PE	DepMap CRISPR Gene Dependency	1.0	2.164
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896852
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41615
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77072
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913045
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850676
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5497
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10328386-DataSheet_1.pdf-0-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2401
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23114
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10638
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6994-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2007
endometrial cancer	GWASdb SNP-Disease Associations	1.0	0.765529
abnormality of immune serum protein physiology	GWASdb SNP-Phenotype Associations	1.0	0.620705
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35308
abnormality of the curvature of the cornea	GWASdb SNP-Phenotype Associations	1.0	0.329663
abnormality of corneal thickness	GWASdb SNP-Phenotype Associations	1.0	0.562717
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04641
HCC1428	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4841
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
PMC12290085-44276_2025_158_MOESM1_ESM.pdf-1-BNC2_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3508
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4202
UST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24429
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79704
H3K9me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1504
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.86656
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.9188
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13642
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8764
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20076
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
HCC2935	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37624
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30719
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.05146
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42041
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0327
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.37161
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24655
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86938
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912444
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33102
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66244
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.172113
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82803
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3023
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-370-GATA1_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01206
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14472
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80597
NCIH2882	DepMap CRISPR Gene Dependency	1.0	6.17389
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7228
BC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00182
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.705692
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78495
keratoconus	GWASdb SNP-Phenotype Associations	1.0	0.562717
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.42604
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52527
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5257
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.593123
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61858
MFE296	DepMap CRISPR Gene Dependency	1.0	13.2111
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.284738
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7996
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913124
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03345
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881525
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Chlorhexidine (diacetate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0198536
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15327
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.083763
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	2.09668
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16356
ZNF254_01_127	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.17495
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.196803
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98574
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44659
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3627
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.183979
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4402-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04005
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950949
BFTC909	CCLE Cell Line Gene CNV Profiles	1.0	1.44735
Vinblastine (sulfate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148889
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8689
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.80109
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02233
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0697
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865007
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.997604
mania	GWASdb SNP-Phenotype Associations	1.0	0.501261
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31369
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1232
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5006-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32632
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54366
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8344
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8527
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09564
IGR37	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52263
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.325838
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961839
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1429
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51179
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05934
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87169
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4037
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56664
diabetes mellitus, type 2	GAD Gene-Disease Associations	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.11042
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45771
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870071
NCI-H128	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50043
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19448
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51337
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8071
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72734
MELHO	DepMap CRISPR Gene Dependency	1.0	2.34069
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46504
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.501261
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59681
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49006
Starch utilization system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851594
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1072
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.05392
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.41252
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.35124
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844931
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30065
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.36449
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31211
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.093738
CP50-MEL-B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0092
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.158817
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5529
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.605862
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18706
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.49202
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09736
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18038
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.854
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27614
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.589304
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3373
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79398
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8519
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6119
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1333
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922491
GBX2-23144817-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4058
uterine cancer	GWASdb SNP-Disease Associations	1.0	0.450882
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN4_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1399
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54016
H3K9me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31304
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S3_LMS_SV-Unnamed_3_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.38067
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16401
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02798
genital neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.268418
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9624
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23075
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.832
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4964-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5615
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.988206
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08954
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4257
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58614
HS-578-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3169
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80885
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU81	DepMap CRISPR Gene Dependency	1.0	2.10541
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14122
Lung squamous cell carcinoma_LUSC_TCGA-77-8140-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4635
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.36764
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7318
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19177
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6771
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11843
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8638100-13045_2021_1211_MOESM2_ESM.docx-1-CAMTA1_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
Filopodium membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9233
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39667
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.147
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48119
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	1.0	1.90664
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28085
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.060318
Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6446
GBX2	ChEA Transcription Factor Targets	1.0	null
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04902
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9174260-41467_2022_30960_MOESM6_ESM.xlsx-S4-RAS1_unique_GATA2-CELSR2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20139
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1213
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850676
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89041
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.20653
MYC	ENCODE Transcription Factor Targets	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.88525
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1089
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58958
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12295
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26437
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50421
depression	GWASdb SNP-Phenotype Associations	1.0	0.362815
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996447
OS252	DepMap CRISPR Gene Dependency	1.0	4.79387
OSC19	DepMap CRISPR Gene Dependency	1.0	6.15993
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996447
Diabetes Mellitus, Type 2	dbGAP Gene-Trait Associations	1.0	0.082091
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875415
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883648
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.075888
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11746
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20422
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32489
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67302
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.154187
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03521
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHU022	DepMap CRISPR Gene Dependency	1.0	16.3892
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04389
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926842
GNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70501
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	2.1381
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52746
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55551
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00254
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.77502
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978184
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84246
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952503
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4011
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0891
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88488
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839487
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00404
dementia	GWASdb SNP-Disease Associations	1.0	0.659337
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834052
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atazanavir (sulfate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0119771
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1816
RB1_KD_GSE50532_654_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2786
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6226
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49196
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855536
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05257
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08766
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84464
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17154
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880692
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26872
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89335
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6937
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04921
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917149
UBAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10093
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1072
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02812
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
hypertrophy, left ventricular	GAD Gene-Disease Associations	1.0	null
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.18568
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63447
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17623
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07929
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19923
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91393
BCOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
AU565	CCLE Cell Line Gene CNV Profiles	1.0	2.44882
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.833483
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949655
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51355
Mucosal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0128
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69298
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61534
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25596
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12368
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886489
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28896
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3837
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851866
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908222
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
AU565	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91757
SMAD4	ChEA Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0852
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41234
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1041
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1739
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38817
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89395
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7724
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.15
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864489
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
alcoholism	GAD Gene-Disease Associations	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.357
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878238
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862227
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.7813
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879369
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79784
OE-33 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	2.1052
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18399
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13381
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926842
GSE143692_2_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09044
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13525
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03865
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66145
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67861
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51158
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923259
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.13491
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38254
Liver angiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859541
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	3.36593
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926842
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EVX2_EVX2	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7825356-8844261.f3.docx-107-TGIF2LY_TGIF2LY	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	3.69173
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4792
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34989
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27028
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	5.06185
HCC33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95903
HH	CCLE Cell Line Gene Expression Profiles	1.0	2.13733
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.809818
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03002
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.8082
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
D-283MED	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05337
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42883
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertrophy, Left Ventricular	HuGE Navigator Gene-Phenotype Associations	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16228
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93904
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.066
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32232
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62383
JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.10138
BL5668 (KANK2)	NURSA Protein Complexes	1.0	null
PROX1_01_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61098
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23937
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.191726
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.35592
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05143
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
BV-173	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03631
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43188
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7712
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.555
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86419
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50346
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935006
hsa-miR-3180-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.45586
abnormality of the endometrium	GWASdb SNP-Phenotype Associations	1.0	0.663117
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01073
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02202
U251MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54565
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17415
Spleen-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	2.03331
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06948
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63619
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8946
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838599
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2546
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.93516
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
59M	CCLE Cell Line Gene Expression Profiles	-1.0	-3.60771
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64307
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73028
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38812
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22526
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.48134
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38274
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25554
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15946
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827438
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
lymph node	HPA Tissue Protein Expression Profiles	1.0	0.823005
neoplasm	GWASdb SNP-Phenotype Associations	1.0	2.09668
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A780-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	3.40788
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46411
Lung squamous cell carcinoma_LUSC_TCGA-70-6722-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46967
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.26376
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05768
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21742
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26633
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14793
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60541
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53372
decreased corneal thickness	GWASdb SNP-Phenotype Associations	1.0	0.562717
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29754
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2987
KARPAS620	CCLE Cell Line Gene Expression Profiles	1.0	1.48603
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0534
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3985
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48299
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886162
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.82977
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21091
myopia	GWASdb SNP-Phenotype Associations	1.0	0.562717
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50821
abnormality of female internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.17496
abnormality of the anterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.191868
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851993
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66545
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70208
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07202
PAX3	ChEA Transcription Factor Targets	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0638
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.04395
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1649
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51009
OUMS23	DepMap CRISPR Gene Dependency	1.0	8.39824
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72343
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41087
reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.229956
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89159
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16331
ZC3H8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02349
SNUC2A	CCLE Cell Line Gene Expression Profiles	1.0	2.24978
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.78668
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69457
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87528
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41425
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68642
ONCODG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80055
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11101
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25634
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.18389
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870071
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Intracellular cyclic nucleotide activated cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.624
KDM5B	ENCODE Transcription Factor Targets	1.0	null
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4974
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.019
POLR2A	ENCODE Transcription Factor Targets	1.0	null
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39858
bone disease	GWASdb SNP-Disease Associations	1.0	0.107955
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60956
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952665
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90224
NCIH1155	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95037
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918504
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840602
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56568
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20076
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OE19	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16331
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887465
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920319
Muscle myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.595
CCDC88A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12735
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.37161
MCF7_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109578
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transcription export complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826755
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17665
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0745
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88321
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34662
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1279
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.272612
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79897
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6352
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4893
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2222
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32266
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00254
Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03361
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21094
Nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.76783
endometrial carcinoma	GWASdb SNP-Phenotype Associations	1.0	0.663117
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64843
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01284
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19411
anxiety disorder	GWASdb SNP-Disease Associations	1.0	0.659337
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44275
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06467
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989051
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GS-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	6.48281
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87831
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97889
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51543
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54359
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09717
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9319
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863224
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9483