association	dataset	threshold value	standardized value
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.374
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07716
Cyclin K-CDK13 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3467
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352059
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76154
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318507
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68216
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.56081
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BB-41-XE67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274029
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06325
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163252
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18085
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4787
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834036
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01207
RCOR1	ENCODE Transcription Factor Targets	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62214
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862794
Tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0578
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2373
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997417
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8353
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429902
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265531
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877753
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161144
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89862
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_4_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dxr protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04253
ZB-33-MZ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337883
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6207
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266321
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20731
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5865
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.371048
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5227
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
PMC12021535-CPH4-15-e70011-s001.xlsx-S21-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904221
GSE71100_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25325
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02109
HC-92-HE59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290827
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953179
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08884
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8241
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8837
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-76-YX69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325283
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36463
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7872
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6986
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850335
PBMC cell line	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.93595
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37672
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32298
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215147
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61369
2414_DUT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.608471
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02477
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7907
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16024
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Eosinophil count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223805
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1355
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5568
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250658
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28338
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi to endosome transport	GO Biological Process Annotations 2025	1.0	null
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3933
NFYA	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288653
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64954
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350974
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7963
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27662
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742316
CBX3	ENCODE Transcription Factor Targets	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5573
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17234
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9968
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	1.74819
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826746
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282046
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854152
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
ATF2	ENCODE Transcription Factor Targets	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6454
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2788
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7594
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5795
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.54478
HMGN3	ENCODE Transcription Factor Targets	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05431
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8255
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79514
hsa-miR-4467	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
1455_CDR2L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.606768
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.83263
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.668
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215412
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8656
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1647
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Trachea	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.616
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.398
Actin wave	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.754
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.32865
KA-62-FE69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229416
CHD2	ENCODE Transcription Factor Targets	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
MD-40-FM63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259679
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171845_4_v_2_ccne1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.673009
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8884
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7399
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39447
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915197
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94668
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162828
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID-90-NM43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304246
BD-69-XG81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202057
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245262
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9442
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Muscle cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4675
HES-3	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.7616
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39725
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5619
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1273
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214503
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06133
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dolichyl-phosphate-mannose-protein mannosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9538
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24161
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IE-13-CP28_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223657
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834036
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15342
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
Latex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916247
Agammaglobulinemia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936249
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28528
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11615
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38213
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytotoxic T-lymphocyte	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.07425
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9152
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9373
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43101
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19423
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16938
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36648
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210408
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.967
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4688
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.103
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.33441
BF-00-PE90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206521
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267873
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.641438
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9967
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4435
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43626
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946272
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501146
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16132
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49874
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24462
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.720392
Waist-Hip Ratio	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378102
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.25011
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3514
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336946
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48793
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19657
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
HD-41-DX72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322987
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1267
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-11-RK51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207809
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839503
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14502
Regulatory T (Treg) cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
2785_EXOC8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.582317
Hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZB-29-GC39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275734
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21897
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18365
JUND	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0952
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992501
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
actin binding	GO Molecular Function Annotations 2025	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.024
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31621
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.40652
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
clathrin-coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6668
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.51099
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.962
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-26-EY87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207712
JF-39-BZ76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200145
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1972
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847552
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327519
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7588
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6579
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210651
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4942
Medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.43
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3686
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.873
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22645
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-66-DP49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.6358
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57122
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285758
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350094
K562_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178542
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.166619
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4994
AC-49-NG46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225291
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334577
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923553
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8517
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277157
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890748
GATA1	ENCODE Transcription Factor Targets	1.0	null
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HC-74-HM63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464323
XC-12-SL04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206062
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231317
KC-10-GC29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273618
EF-75-JG46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271066
CTCF	ENCODE Transcription Factor Targets	1.0	null
Cell division site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.58
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45981
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3897
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08363
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14652
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22645
TCF3	ENCODE Transcription Factor Targets	1.0	null
JE-22-JR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351775
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
IRF3	ENCODE Transcription Factor Targets	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0043
cofilin-actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
bone marrow	HPA Tissue Gene Expression Profiles	1.0	0.896253
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372097
Hepatoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Microspike	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
abnormal actin cytoskeleton morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of hippo signaling	GO Biological Process Annotations 2025	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Polarisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
PMC12358297-41388_2025_3481_MOESM3_ESM.xlsx-S9_ASCL1-regulated_genes-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8629
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36734
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254946
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614232
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.714
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07571
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5483
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230754
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18027
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56341
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62433
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09411
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34993
helper T-lymphocyte	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.06014
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.514543
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.864318
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218941
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.59496
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.98052
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
post-Golgi vesicle-mediated transport	GO Biological Process Annotations 2025	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2685
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HD-18-YL30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274353
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37811
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Waist-to-hip ratio adjusted for BMI (additive genetic model)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.23979
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PC-44-DH10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335036
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209445
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0876
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6918
Lymphoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF143	ENCODE Transcription Factor Targets	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8733
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835775
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639624
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124509
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944781
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0749
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.737546
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16677
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276929
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9473
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88024
AA-68-OJ16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.729264
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KC-26-JQ92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286739
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61394
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8772
AA-52-JS03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200553
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-81-ZH14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225725
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0625
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289898
PD-60-FM93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295669
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62844
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.650419
IRF1	ENCODE Transcription Factor Targets	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930853
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7705
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381653
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-08-CM08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285421
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13696
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0833
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358891
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420522
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.25638
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98171
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49847
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442809
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329416
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33169
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.963841
USF2	ENCODE Transcription Factor Targets	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58172
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.497
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1278
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
MCF7_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014705
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12612
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896797
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormal Golgi apparatus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3458
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499862
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1701
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1998
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330945
IC-05-WD74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255911
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8111
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
B-lymphocyte	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.82823
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8617
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5246
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76345
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3973
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0704
PBX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ME-16-XW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260018
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7305
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258922
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
CRCGN017_MCF10A.WT.HP_24H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07325
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525901
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34065
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBV-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47056
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3401
PMC12585103-pbio.3003444.s013.xlsx-List_of_genes_for_GO_analysis-List_of_genes_undergoing_significant_MXE_upon_PRMT5_KD_under_hypoxia_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48793
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252823
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Interphase microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
Podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
CUX1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.18791
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415697
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2336
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25804
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.17353
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
PB-40-CS17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215754
REST	ENCODE Transcription Factor Targets	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.705788
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284609
BA-15-VE07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241387
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3703
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15253
proton-transporting two-sector ATPase complex, proton-transporting domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33634
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26718
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
Deep fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
BRCA1-BARD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251076
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.187
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367062
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.51141
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36871
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Leading edge of lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Chondrodysplasia	DisGeNET Gene-Disease Associations	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48793
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397753
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903783
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.594884
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.452
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43101
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
CCR4-NOT core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1003
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
Myosin II filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34993
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202214
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260534
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2968
K562_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183012
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9014
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7045
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302012
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464294
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259011
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2083
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337711
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09139
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915932
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229771
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.8772
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9245
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.64402
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4435
k29	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7584
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128076_2_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232805
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466015
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31675
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Severe combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dendritic growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7758
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07716
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989731
HT144	CCLE Cell Line Gene CNV Profiles	1.0	2.3051
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-39-BD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.315339
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB-78-PA58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2539
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3335
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.87043
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40671
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0158
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76345
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282737
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901392
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
JA-77-UH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214271
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5421
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31122
NCIH2405	CCLE Cell Line Gene CNV Profiles	1.0	1.53777
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9441
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17994
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412911
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5646
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Legionellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-85-LB25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205551
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07717
6771_PRKRIP1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524156
Podosome ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62095
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44993
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BF-89-QD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229974
NFYB	ENCODE Transcription Factor Targets	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.21729
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-56-XL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204447
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239498
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85592
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297706
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.52
A549_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151282
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.799361
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5518
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.18707
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208252
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19135
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930677
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09321
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.99544
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9566
KB-49-NF63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221189
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.465436
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.953167
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854152
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	1.33434
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
PHF8	ENCODE Transcription Factor Targets	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827246
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04299
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
RD-89-FH52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211959
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1271
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73194
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7222
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2422
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Spondylometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.174
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06627
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.154
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71107
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247351
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4078
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1803
A549_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159347
CEBPB	ENCODE Transcription Factor Targets	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344362
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753651
CRCGN009_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59099
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
Erectile dysfunction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173237
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.966814
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42571
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16528
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883237
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210835
testis	HPA Tissue Protein Expression Profiles	1.0	0.950897
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8263
BD-45-EU45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221838
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65742
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360391
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80488
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cryptococcosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9949
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
NB-17-SQ59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518971
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0756
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416369
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LB-65-SM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241424
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75605
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7228
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03884
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205747
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58407
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21552
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.75293
FA-65-UA27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.405466
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30562
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293651
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15404
GD-08-JL45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.403547
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.397
CC-86-IO63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217315
LNCaP cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.923917
CRCGN015_MCF10A.WT.HP_24H:E02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46384
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02669
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23246
K562_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137073
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45855
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9541
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.875287
CREB1	ENCODE Transcription Factor Targets	1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.75013
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.584608
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31882
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9797
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HE-34-ZC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212436
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Legionnaires' disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0347
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1701
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00532
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of hippo signaling	GO Biological Process Annotations 2025	1.0	null
NF-21-HQ00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.628924
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.555
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01577
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wiskott-Aldrich syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9301
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8506
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2648
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD-86-UW46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216548
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Juvenile absence epilepsy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52202
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.688336
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218896
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29268
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.718
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321263
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219669
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376584
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2161
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236915
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0402
Combined T cell and B cell immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5388
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RXRA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.652
CF-22-IS33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246884
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834036
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.584899
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424027
KC-36-DK23_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308984
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7633
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2532
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907805
PML	ENCODE Transcription Factor Targets	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5568
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-76-YX69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23816
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07571
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96532
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301388
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226888
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-62-MI89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237864
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
Pleomorphic adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714125
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.56592
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2391
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.75
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38987
TCCPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.32833
FD-62-ZB67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209859
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.547
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.56081
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DE-98-FC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30883
DB-18-UF01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237223
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2938
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280336
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.96729
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.563
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.634
NFE2	ENCODE Transcription Factor Targets	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203544
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4001
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33815
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6222
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_2_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41107
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229281
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.0426
Filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0326
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0584
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22305
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11078
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939397
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412036
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Heel bone mineral density	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9531
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997557
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18262
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.88112
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_1_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7841
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943817
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36253
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4947_MED24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.707996
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-33-HT38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215133
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51274
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894458
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GD-39-YG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325683
4946_MED23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.782532
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391992
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.397
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27982
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246375
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876298
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81316
RB-55-KL42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270305
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75605
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834036
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00759
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34562
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30175
Ra-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-84-IJ41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200745
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39274
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22854
CRCGN014_HEPG2_3H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05356
Eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968394
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0122
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215317
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328209
LF-35-CP32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211984
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.976446
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.65346
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MECO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
cytosolic transport	GO Biological Process Annotations 2025	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.83011
Liver cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.18879
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K-562 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.851115
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.972
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3947
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26482
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297369
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02238
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9837_WDR70_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.649742
RELA	ENCODE Transcription Factor Targets	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WB-54-WD35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235475
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234632
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.443779
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3571
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33611
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960375
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156386
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.718
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3536
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasmic side of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.829
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.142601
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3429
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46293
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390854
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265424
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.307
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280234
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5751
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8844
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
AB-25-XU75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211597
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219802
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.822281
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9229
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.522516
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Amoeba	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275766
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01404
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30122
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MCF7_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158263
PMC4335056-pone.0116726.s005.xlsx-X-ChIP_NOT_TX100_QE-GENE_Official_symbol_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	1.0	2.04988
Mucocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.989
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2007
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.95549
Immunodeficiency 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06627
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17478
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.874
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.284
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1025
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3092
GSE126463_4_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3315
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.03155
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278362
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.47231
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215869
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8595
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43851
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13147
Mating projection tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5924
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1026
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838255
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
QB-69-QH67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261545
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20691
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
post-lysosomal vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.56
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45504
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7529
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969898
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416052
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6515
WD-65-PA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275497
Arp2/3 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.7
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20904
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54702
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7901
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.567
EC-96-OH91_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250291
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-663	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26718
HDAC1	ENCODE Transcription Factor Targets	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3303
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.82362
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2279
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.988
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3092
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01391
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25041
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16477
Ameloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293669
Plasmodium falciparum malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424073
CRCGN011_HEPG2_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0389
MCF7_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150532
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fungal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.24
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5844
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214257
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3539
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZD-74-FC07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238706
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980304
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00063
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.689193
Basal ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
enhanced wound healing	MGI Mouse Phenotype Associations 2023	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9662
CRCGN017_MCF10A.TP53.M_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53458
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.7837
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.949155
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66613
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1637
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919007
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41064
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.00217
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59308
MHCC97-L cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49557
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3284
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.67885
GSE143782_7_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312157
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.243
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25509
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355409
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1982
AD-45-YB25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290347
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42071
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-21-FY25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.556417
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51242
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18145
Mixed	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.36777
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365167
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34707
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8139
HA-32-YH61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209925
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29224
GABPA	ENCODE Transcription Factor Targets	1.0	null
LC-96-WR85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204026
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3893
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QE-79-XO29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216931
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
Inhibitory neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
BA-19-VU85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245162
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329963
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545357
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3618
Transcription factor TFIIE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Subpellicular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38274
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0273
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.856873
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8646
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11154
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.521682
AX-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
Early phagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.681
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.589674
AE-72-UP91_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209579
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5816
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294827
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210711
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53091
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35505
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-86-BE39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21452
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87831
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2455
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220682
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5037
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57855
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59843
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384658
AB-09-JN93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213158
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251918
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.0762
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.42419
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46027
MAFF	ENCODE Transcription Factor Targets	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7763
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.44039
YE-55-YX75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211678
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.882734
NC-76-YX69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375076
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.6406
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270382
8669_TAF7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.511408
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
A body shape index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
K562_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107428
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89577
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.0763
AB-04-NN16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239429
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7915
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4475
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4801
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12522
actin polymerization or depolymerization	GO Biological Process Annotations 2025	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1731
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203985
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.15229
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6948
SP4	ENCODE Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4108
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6161
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.741
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671986
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4619
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8538
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7709
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308077
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Myosin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.503
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01356
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.846492
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236781
PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564791
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3332
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
FD-62-ZB67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32088
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8335
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9798
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_1_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BB-10-PR06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255255
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349436
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37002
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.595504
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1579
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8366
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.959226
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0448
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-46-FY47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296406
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20488
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75824
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.559
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9924
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06608
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3741
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230683
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309433
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-30-VB23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248524
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-44-DH10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324428
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0597
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.190917
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37294
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34046
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
proton-transporting ATP synthase complex, coupling factor F(o)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KC-67-HN97_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22613
OC-71-BZ81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244023
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88398
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.684828
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276475
Intranuclear rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
CRCGN016_MCF10A.TP53.M_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3644
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2033
RXRA	ENCODE Transcription Factor Targets	1.0	null
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.899
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.49149
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Contractile vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312173
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.34054
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
Pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930853
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232049
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7653
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348574
Corona	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
Cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
Myosin XIV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330879
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307958
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7414
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.414
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33165
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52518
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525207
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58255
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10885
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95912
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.900712
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38769
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Macropinocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.465
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162892_4_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444003
CRCGN009_HEPG2_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07444
TAF1	ENCODE Transcription Factor Targets	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935197
CD-03-QC42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2332
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39871
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Oculoglandular tularemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207305
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44907
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07012
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883237
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	0.9322
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85459
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5031
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918018
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3982
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.969879
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9395
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245921
Transnitrosylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.743938
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.875287
ME-93-CO85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20705
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16091
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256134
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742254
Mitotic spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.421417
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2573
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211238
K562_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190272
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2955
DB-01-BR68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201362
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26718
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.29255
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9606
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.385
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3185
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30827
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337828
gdm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15404
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242913
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.975248
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274405
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202918
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246002
283_ALS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.523216
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29547
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37496
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.492559
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237454
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
DD-68-ZP95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228028
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2181
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38827
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61804
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.643902
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.539
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01302
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373358
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221015
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.987523
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854152
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29254
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834036
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
natural killer cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.22164
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218693
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8522
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3492
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5285
LC-96-WR85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231997
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7556
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.749
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1273
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6585
RFX5	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313202
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8409
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839665
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67301
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8076
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12982
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7212
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854152
CHD1	ENCODE Transcription Factor Targets	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.907727
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17625
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3279
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7374
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85105
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9625
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.95563
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25409
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42585
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73079
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968394
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06045
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.548
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8634
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885804
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.947365
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7746
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20185
Rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6024
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8563_STXBP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505762
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.750491
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14808
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.706
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dhd/k12/trb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11339
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22131
GSE185744,GSE185747_0_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393187
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998512
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28085
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.967
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9672
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1193
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91748
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249712
8653_TAF12_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.618991
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.197
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MF-41-QM60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02197
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.09589
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_downregulated-Genes_downregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30313
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944313
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15253
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264273
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872742
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14795
K562_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177533
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892081
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285957
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416887
BA-53-FM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240134
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.564851
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39613
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247108
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.90322
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-07-LL18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.608881
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
XC-61-SE50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.552852
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.53742
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0401
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0481
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44351
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939955
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
MXI1	ENCODE Transcription Factor Targets	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3911
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865137
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-21-FY25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245376
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507573
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882153
AA-12-VW53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38252
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
K562_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187807
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.719
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2423
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6006
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.606298
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3422
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207849
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6956
FOS	ENCODE Transcription Factor Targets	1.0	null
DB-56-XL71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267302
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.005
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
AP-3 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53834
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GF-32-FY02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432705
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22338
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
Contractile vacuole pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922505
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4983
RH18	CCLE Cell Line Gene CNV Profiles	1.0	2.19302
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr16_4434612_A_G_b38	GTEx eQTL 2025	1.0	1.11624
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.131
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0561
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-72-RI24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410494
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
OB-15-UL37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275223
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423675
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8418
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3591
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7893
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833117
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320684
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Capecitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163072
PAX5	ENCODE Transcription Factor Targets	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.4762
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.609283
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8725
EE-64-WM03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273041
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08675
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44876
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
UBTF	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Exopher	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2609
ME-16-XW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.435892
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294373
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4054
actin filament polymerization	GO Biological Process Annotations 2025	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75824
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Laticifer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45979
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.576141
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
WA-03-IF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600787
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pedal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55305
EGR1	ENCODE Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45887
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273667
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402036
AD-18-XC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239458
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.55234
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0762
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.758305
Equatorial cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994013
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89928
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
T cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TC-66-CI47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41684
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-01-HO61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266488
hsa-miR-3960	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	208.91
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24953
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1044
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.02
J-774 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.94
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7734
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357235
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
Bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.68083
MAZ	ENCODE Transcription Factor Targets	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.889
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208391
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71875
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
protein polymerization	GO Biological Process Annotations 2025	1.0	null
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940613
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352125
Cytostome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.732
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10517
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7058
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0444
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898172
LD-37-JE11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248989
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300679
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0724
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-77-VS60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258919
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.439
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.5872
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910517
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.878462
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00889305
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.569672
K562_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154916
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59207
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.619
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7046
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rhoptry neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15753
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319911
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886749
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.33657
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	1.38028
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.57683
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964978
increased fibroblast cell migration	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
coronin-1A deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.091
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897817
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.675845
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961166
Systolic Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9607
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.779266
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353399
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02356
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HB-24-GP45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242081
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4516
JE-72-KV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265729
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49249
AD-51-FB60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273101
ATF3	ENCODE Transcription Factor Targets	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206423
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4749
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
Rhizomelic chondrodysplasia punctata type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877069
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0073
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8706
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7307
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Unnamed_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
3994_HUWE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.536682
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.573925
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03875
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229301
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1997
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4575
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01375
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9235
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27871
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992516
AD-09-MD49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406513
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TB-06-VB30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254809
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276758
Actin tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.524
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06627
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924367
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4322
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04177
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45295
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333808
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235786
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7959
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1154
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13542
MF-81-RJ18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305378
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637812
BB-27-MC77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228629
abnormal cell adhesion	MGI Mouse Phenotype Associations 2023	1.0	null
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.97
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410033
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.5518
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.88
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2884
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:B03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32151
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08139
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
High light scatter reticulocyte percentage of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247223
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Growth cone lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
RB-55-KL42_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257552
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.494387
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF-43-DT71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265151
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6535
FtsQBL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
AD-58-PW17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243316
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.984604
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.418
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207351
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoproct	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40719
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2349
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.034
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.838
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896797
RIDDLE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251874
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49575
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236613
BRCA1	ENCODE Transcription Factor Targets	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9047
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.51527
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203553
Podosome core	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23715
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3786
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885779
KNS81	CCLE Cell Line Gene CNV Profiles	1.0	1.71756
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-21-VE32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.786603
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218592
MCF7_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168417