association	dataset	threshold value	standardized value
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5902
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073305
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.627083
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ray cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16182
amoxicillin_rattus norvegicus_gpl341_colon_gds1273	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
photosystem ii reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.755891
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
DA-07-LL18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301637
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
JAK2_knockdown_192_GSE54645	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.95265
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09443
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7626
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49095
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17062
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31784
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53353
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.02896
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364513
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75456
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81793
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.82289
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78337
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27351
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93859
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
abnormal lens morphology	IMPC Knockout Mouse Phenotypes	1.0	null
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
metalloexopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94004
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14139
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7416
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gramine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63742
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9156
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33017
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085315
peptidase activity, acting on l-amino acid peptides	GO Molecular Function Annotations 2015	1.0	null
Mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15636
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
NCIH838	CCLE Cell Line Gene Expression Profiles	1.0	1.42084
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50015
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02983
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.1862
experimentally	GeneRIF Biological Term Annotations	1.0	null
Mating projection tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36826
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7264
POU5F1_01_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60565
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.0005
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
New mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
CEBPD-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09555
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.40497
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9634
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00362
silver-russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07698
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34307
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
KNS60	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.21138
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44098
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2192
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.123158
cellular macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60782
DB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41602
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6815
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
studied	GeneRIF Biological Term Annotations	1.0	null
BRD-K89402302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06506
H376	DepMap CRISPR Gene Dependency	1.0	2.08039
BRD-K66187822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08314
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32936
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
mafenide-1441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74117
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1072
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30725
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062465
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60181
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2928
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
C32	GDSC Cell Line Gene Expression Profiles	1.0	1.97907
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K44908610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29832
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14764
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
carboxypeptidase activity	GO Molecular Function Annotations 2025	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2881
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53891
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896792
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08268
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.815
BRD-K45042519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33281
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5525
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12857
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.19376
BRD-K51217456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39484
Pancreatic secretion	KEGG Pathways 2026	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99258
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08385
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292436
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78769
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-XBED-2426-SM-4AT4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24527
GSE155830_1_v_0_fkbp5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907863
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K03562091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31063
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84515
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961472
PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21177
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Plastid outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
BRD-K25045770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08796
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226331
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00112
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
BRD-K33005275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51414
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50818
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82315
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
HT	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51597
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2499
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89408
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20493
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885961
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01072
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966758
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19142
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.3582
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837113
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16312
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.93083
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.792
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.455284
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.884244
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07415
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75453
HCT116	DepMap CRISPR Gene Dependency	1.0	2.45334
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4092
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90307
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.59172
SAP30	ENCODE Transcription Factor Targets	1.0	null
Growth Disorders	CTD Gene-Disease Associations	1.0	1.41613
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84741
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090368
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25403
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE450	DepMap CRISPR Gene Dependency	1.0	2.08681
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Antennal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
aorta thoracica smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216426
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
wild	GeneRIF Biological Term Annotations	1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39622
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89902
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.83103
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
superfamily	GeneRIF Biological Term Annotations	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.5839
isoconazole-1372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99428
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15636
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858474
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22678
IST-SL2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63077
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11439
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31534
BRD-K49148914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4632
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66395
BABAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23655
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02544
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945256
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25856
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01156
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18927
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2968
BRD-K40697889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03755
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049658
JVM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95889
tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.926764
BRD-K63964208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.011
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858718
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17902
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Anoxia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K52685199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18531
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41277
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01126
Precursor B-Cell Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7837
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.96502
PMC6129574__F5	PFOCR Pathway Figure Associations 2024	1.0	null
MRPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65165
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89332
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27814
female infertility	MGI Mouse Phenotype Associations 2023	1.0	null
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60971
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2297
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077033
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98268
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043192
A2780	GDSC Cell Line Gene Expression Profiles	1.0	1.77407
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60605
BRD-K93486666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18568
Perturb_8451_KD_EphA2_SRP237314	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
thylakoid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.08628
HCC78	DepMap CRISPR Gene Dependency	1.0	2.08235
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.08797
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12907
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
HNRNPL_02_96	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.48113
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52989
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926083
SNUC1	DepMap CRISPR Gene Dependency	1.0	3.22886
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28687
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405935
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8935
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79335
BRD-K20435953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12873
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16281
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.918829
CRCGN015_MCF10A_48H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20893
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
metallopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ZNF658	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62414
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60759
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.872509
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33879
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.703581
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77731
nmr	GeneRIF Biological Term Annotations	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27593
atomic	GeneRIF Biological Term Annotations	1.0	null
naloxone-4645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9477
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39912
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947887
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K66963616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01406
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03621
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36211
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19729
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10932
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9489
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94194
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23831
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916974
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
PMC3296254__F5	PFOCR Pathway Figure Associations 2024	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31388
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
exopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45273
Larval integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0299
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50784
pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231102
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
stomach	GTEx Tissue Gene Expression Profiles	1.0	1.20379
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-2.16504
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
alpha-ergocryptine-4552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63827
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89857
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56161
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936449
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05467
ATR_KD_GSE54268_664_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8084
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23522
Gas vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.231
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22498
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
proxyphylline-3115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11582803-41598_2024_80483_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_MR_analysis_of_Proteome_wide_Mendelian_Randomization_FinnGen_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04769
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9731
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4634
BRD-K04695511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04126
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043887
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08735
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23395
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7288
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12857
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44205
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05061
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08884
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.92678
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Epipodite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94194
BRD-K43292469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16555
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33599
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.5535
Hypoxia	DisGeNET Gene-Phenotype Associations	1.0	null
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56848
protein catabolic process in the vacuole	GO Biological Process Annotations 2025	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48169
MM426	DepMap CRISPR Gene Dependency	1.0	4.01139
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03438
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11841
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03946
chlorphenamine-1371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20545
invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456442
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mast cell granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.572162
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	2.28415
BRD-K62219570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02346
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84148
Anoxia	CTD Gene-Disease Associations	1.0	2.88009
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24449
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456055
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932951
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18557
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93267
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87877
cation binding	GO Molecular Function Annotations 2015	1.0	null
Zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29952
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2802
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.51596
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43295
BRD-K72216066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72084
metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC12529848-12967_2025_7217_MOESM3_ESM.xlsx-Table_S4-Table_S4_Associations_of_genetically_proxied_proteins_with_risk_of_atrial_fibrillation_by_MR-SPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099432
EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39866
SW982	DepMap CRISPR Gene Dependency	1.0	3.39109
pancreas	HPA Tissue Gene Expression Profiles	1.0	2.24804
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32024
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.323075
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
PMC4100111__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cladode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
NCIH1618	CCLE Cell Line Gene Expression Profiles	1.0	1.61086
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27299
BRD-K02778241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18535
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057008
determined	GeneRIF Biological Term Annotations	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K70378808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43694
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1431_KO_Prmt7_SRP362551	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.452
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0753
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K03849840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85987
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915661
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.54864
light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.777755
OVCAR5	CCLE Cell Line Gene CNV Profiles	1.0	1.78442
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887067
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71073890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16367
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8966
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.92953
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24624
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25469
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
mepenzolate bromide-3748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.20149
CENPVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73532
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233641
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6478
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90746817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11841
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM5-23873026-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77275
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02979
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9557
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59623
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
Dried cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
ILRUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15494
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10396
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80312
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30613
COLO704	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19933
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24133
KMRC20	CCLE Cell Line Gene CNV Profiles	1.0	1.50985
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68542
BRD-K75889393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37371
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59463
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35867
BRD-K34700473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32701
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0056
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96753
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.689492
JHH1	DepMap CRISPR Gene Dependency	1.0	2.07207
BRD-K33287655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23181
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02737
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
computational	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54375
BRD-K35596700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26477
golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29996
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.13674
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03943
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65462
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Uropod membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16626
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16347
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861042
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5729
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_13-Table_13_MR_Steiger_analysis_to_infer_the_MR_causal_orientation_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28767
cardia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463013
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07415
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02608
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853112
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC6129574__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42923
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55549
Perturb_16117_KO_Mfn1_SRP189355	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.36437
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
CRCGN015_MCF10A.TP53.M_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26275
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446807
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71349
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870765
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51742
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26541
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57356
A101D	CCLE Cell Line Gene CNV Profiles	1.0	2.1164
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87348
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
DENND4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95117
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.82663
BRD-K08570368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44583
SW1116	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76426
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.899871
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13177
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8813
CTV1DM	DepMap CRISPR Gene Dependency	1.0	10.6316
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1771
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18185
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43875
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.462798
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37172
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89513
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36567
CRCGN012_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27927
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC12503973-3972293.f8.xlsx-Supplementary_table7-Supplementary_Table_8_MR-PRESSO_Results_in_the_Discovery_and_Replication_Phases_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829137
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.21105
H357	DepMap CRISPR Gene Dependency	1.0	2.36845
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
BRD-K00846914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26163
PancreaticIslet	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
gallbladder	HPA Tissue Gene Expression Profiles	-1.0	-1.16313
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44212
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16715
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76559
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
active	GeneRIF Biological Term Annotations	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
misfolding	GeneRIF Biological Term Annotations	1.0	null
head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295297
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65817
Bract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25224
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86877
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06207
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08779
type	GeneRIF Biological Term Annotations	1.0	null
procarboxypeptidase	GeneRIF Biological Term Annotations	1.0	null
Potassium ion-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.979
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16933
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825136
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57564
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51221
EW8	DepMap CRISPR Gene Dependency	1.0	8.18245
stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20501
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01794
Pancreatic adenosquamous carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectus femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29903
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41762
FEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52078
Platelet alpha granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
tiapride-3663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087813
PMC3296254__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65103
Autistic Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07769
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4361
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8744
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75418
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115504
PMC12823428-43587_2025_1018_MOESM3_ESM.xlsx-ST12-Supplementary_Table_12_Main_mendelian_randomisation_results_of_plasma_proteins_on_delirium_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890203
Meningioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
fulvestrant-2698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
three	GeneRIF Biological Term Annotations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057948
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
backbone	GeneRIF Biological Term Annotations	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
SUM185PE	DepMap CRISPR Gene Dependency	1.0	10.7596
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2618
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-81-RI20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295356
BRD-K90444258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0758
CRCGN011_HEPG2_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10825
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
SKMM2	Achilles Cell Line Gene Essentiality Profiles	1.0	2.00285
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29909
PRDM5-23873026-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
ATM_knockout_74_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.27932
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10941
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86119
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916103
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.986116
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
Megalencephalic leukoencephalopathy with subcortical cysts	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
0225151-0000-6384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23376
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1483
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068726
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82664
cellular process	GO Biological Process Annotations 2015	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-215-PAX4_PAX4	Rummagene Transcription Factor Associations 2026	1.0	null
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
BRD-K90157100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93997
Inflammation	CTD Gene-Disease Associations	1.0	1.28518
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CCT4	Hub Proteins Protein-Protein Interactions	1.0	null
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21526
BRD-K70652938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56596
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40219
15273739-Table2	GeneSigDB Published Gene Signatures	1.0	null
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.91238
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
Zymogen granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82507
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Ornithine carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29716
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02293
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23009
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911329
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10327
Perturb_4744_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.9005
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894034
Perturb_17454_KO_Insr/Igf1r_SRP091479	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49758
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72827
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83471
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
methyldopa-5272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
PMC4100111__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-3.03628
Hypersensitivity, Delayed	CTD Gene-Disease Associations	1.0	1.06917
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66779
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
butylated-hydroxytoluene	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3053
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65995
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09407
JA-63-WB39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224751
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894804
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931305
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.713
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90755
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47615
MKN45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73217
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162505
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93015
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13562
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
photosystem ii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.23713
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88087
BRD-K65395967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10536
lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361901
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05226
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
STAT1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12118
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5581
RMUGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13859
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.132539
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38727
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85619
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32142
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76639
sitosterol-7332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85664
progesterone-3287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.16521
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37053
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22996
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Table_S6_Overlap_of_differentially_expressed_genes_in_Tg_HSP_EWS-FLI1_embryos_and_human_EWS-FLI1_signature_from_Smith_et_al_2006_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05297
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Neoplasms	CTD Gene-Disease Associations	1.0	1.40288
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.67778
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23054
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65925
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932035
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426872
icSARS CoV_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.63426
Pancreatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985652
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08615
BRD-K41192068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1479
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84562
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71648
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60531
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22541
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31648
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22201
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8352
BRD-K86089324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04192
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.429
RH41	CCLE Cell Line Gene Expression Profiles	1.0	1.35428
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K60456515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15054
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.5278
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881967
BRD-K72721410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18519
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89209
UACC257	CCLE Cell Line Gene Expression Profiles	1.0	2.13544
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928743
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
BRD-K94132559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37702
folding	GeneRIF Biological Term Annotations	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8924
peptidase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08869
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334865
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45859834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0091
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12231
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02981
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.58994
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00614
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5809
NIX_Deficiency_GDS2630_655_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19
Human - Fetal Development - L1 - Acinar cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K86240647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1681
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06341
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80512
myosmine-4293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
BRD-K39584933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26347
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27971
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33414
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57559
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.85685
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
IE-75-ZC91_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328064
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3512
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978142
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metallocarboxypeptidase activity	GO Molecular Function Annotations 2023	1.0	null
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40471
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14601
protein catabolic process	GO Biological Process Annotations 2023	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2107
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93812
Hypoxemia	DisGeNET Gene-Phenotype Associations	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3298
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K81543095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02098
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-08-NY46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511722
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53588
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280299
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99352
glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.339806
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
Perturb_6588_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.47016
LY-294002-6195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16955
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3443
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CF-15-GU15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.407847
15902281-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1492
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49161
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891675
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.43741
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66065
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76237
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02893
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875643
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
proteolysis	GO Biological Process Annotations 2015	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905024
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC12276197-18_2025_5784_MOESM1_ESM.xlsx-Sup_Table_10-Supplementary_Table_10_ERK_targets_from_Unal_et_al_2017_mapped_to_human_orthologous_genes_from_KD_and_SC_hypernetworks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042743
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10625
PMC9949195-media-2.xlsx-25_WHI_AA-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
mefloquine-1364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
stomach	HPA Tissue Gene Expression Profiles	1.0	1.0882
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86227
Multiple benign melanocytic nevi_Epidermis_GSE3189	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44657
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43708
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05006
PMC11257892-Table_1.xlsx-S2-Supplementary_Table_S2_All_results_of_the_preliminary_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARD-23208498-MDA-MB-231-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02737
fleroxacin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37392
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12607
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74121
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40251
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01269
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
carbenoxolone-4173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
decreased circulating chloride level	IMPC Knockout Mouse Phenotypes	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7621
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
BRD-K24319929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36119
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60166659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15967
Flavedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50087
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28816
SKMEL1	CCLE Cell Line Gene Expression Profiles	1.0	1.94066
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
PMC9314667-Table_1.xlsx-Regulons-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994721
NOTCH_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
albendazole-oxide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24997
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28279
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76209
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03989
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26931
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854425
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28202
BRD-K36563688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0896
BRD-K71437774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11685
LI7	CCLE Cell Line Gene Expression Profiles	1.0	1.80024
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2672
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.16313
PMC4742856-srep20328-s7.xls-Sheet2-ZF_converted_to_Human_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043269
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09505
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pyrophosphate-dependent phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metanephrine-2015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
Perturb_15828_OE_Nrf2_SRP291726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.00618
BRD-K85359206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18793
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7571
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.027
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04623
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53428
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC6488628__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.09401
kinetics	GeneRIF Biological Term Annotations	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53683
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911903
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
Tube foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
BRD-K03070961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82837
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX17_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53206
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.12042
17284363-Table3	GeneSigDB Published Gene Signatures	1.0	null
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.40212
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K86300178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29312
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06046
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25881
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6727
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899506
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206662
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87711
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
BRD-K94516254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06931
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25602
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33048
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superimposable	GeneRIF Biological Term Annotations	1.0	null
Sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7428
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
MALME3M	DepMap CRISPR Gene Dependency	1.0	4.45615
JUN_KO_GDS4205_294_mouse_B lymphoid cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.02865
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60712
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9272
BRD-K74317118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08318
proxyphylline-6494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874825
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35591
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29249
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12593
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Perturb_14524_KO_LRHt_SRP009598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.00218
BRD-K28339544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03741
PMC11748740-41598_2025_85338_MOESM1_ESM.xlsx-Table_S2-Table_S2_The_cis-pQTLs_Pass_Instrumental_Variable_Selection_Test_for_Primary_MR_Analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0325
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.404
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-K42663371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43324
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872757
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2559
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
BRD-K19390761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43823
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828732
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28674
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.51762
ICC9	DepMap CRISPR Gene Dependency	1.0	4.04471
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01595
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48099
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0422
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3913
Lung squamous cell carcinoma_LUSC_TCGA-66-2800-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50081
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88083
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72691
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47948
TMSB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94139
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6517
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CHP212	DepMap CRISPR Gene Dependency	1.0	3.03333
Lung squamous cell carcinoma_LUSC_TCGA-77-8156-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ma91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3027
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02727
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
BCCIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90296
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232744
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50386
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02737
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36066
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02647
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
doxorubicin-4610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
photosystem ii oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.729284
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471927
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19
LN-405	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56824
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33568
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2023
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
PBX1	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938677
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01698
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00829
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0665
protein catabolic process in the vacuole	GO Biological Process Annotations 2015	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2963
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875597
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01456
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44809
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57492
NDUFAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63265
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871948
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34426
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065457
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61651
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.07461
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3147
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17492
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATG12	Hub Proteins Protein-Protein Interactions	1.0	null
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80795
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04977
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984154
BRD-K63462027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30103
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050893
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38881
BRD-K57186295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3524
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03758
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95414
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46311
LS1034	DepMap CRISPR Gene Dependency	1.0	2.73921
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04009
BRD-K49945344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27368
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8699
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
Perturb_14838_KO_Klf14_SRP314854	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.06546
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02981
CE-00-EK89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508421
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922533
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3695
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43403
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.601909
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37706
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.204
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81628
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040575
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6215
BRD-K76583861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5965
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69538
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03734
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37382
Exocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7356
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68517
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61572
JHUEM7	DepMap CRISPR Gene Dependency	1.0	3.32797
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78783
19621087-Table1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930694
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K03515786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29469
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	1.62193
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17388
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82576
LOVO	DepMap CRISPR Gene Dependency	1.0	3.40084
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65488
MXI1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5302
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93747
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49224
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19649
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35413
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9294
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988252
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11609
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
SB-89-QK94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280029
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44098
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87493
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86841
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.1731
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09808
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6798
STAT3_01_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58933
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83823
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
ERRalpha_Deficiency_GDS2727_646_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24361
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.944836
Prestwick-664-4737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	2.05937
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35345
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
conformations	GeneRIF Biological Term Annotations	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13087
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51391
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.52515
TMSB15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01922
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95525
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.1618
CRCGN017_MCF10A.WT.HP_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11209
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01839
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380251
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_14_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3102637-1471-2105-12-99-S2.XLSX-11_sigpathways_in_AA_P_0_001-Unnamed_19_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
site	GeneRIF Biological Term Annotations	1.0	null
JHOM1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22982
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3065
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
A2780	CCLE Cell Line Gene Expression Profiles	1.0	2.30408
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72436
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10932
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4891
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7818
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32198
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0676
chrysophanic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37249
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59679
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12376
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	1.0	2.29743
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045077
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839589
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0294
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NIHOVCAR3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13478
Gall bladder epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43794
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06687
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936449
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3655
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H520	GDSC Cell Line Gene Expression Profiles	1.0	2.85145
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04805
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Nuclear dicing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
BRD-A89499670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42078
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35739
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25531
Anoxemia	DisGeNET Gene-Phenotype Associations	1.0	null
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83975
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94263
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67363
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40498
BRD-K06208863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26063
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932951
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61897
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32758
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	2.49548
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34596
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23005
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33395
mp12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2558
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90405
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.27636
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45321
PMC5994134__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24171
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.30728
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61427
hMPV_12Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39434
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00474
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-14_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83371
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1272
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.812309
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63739
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166643
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3353
BRD-K99214816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1728
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56271
BRD-K71243741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11223
17297478-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
exopeptidase activity	GO Molecular Function Annotations 2025	1.0	null
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63463
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9482
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46415
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65587
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.84757
KDM1A	ENCODE Transcription Factor Targets	1.0	null
aggregation	GeneRIF Biological Term Annotations	1.0	null
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054563
CORL23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18165
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288357
VAL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nilutamide-3104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
methotrexate-5000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEC1A	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22883
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43769
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430779
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21012
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48323
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12526
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
been	GeneRIF Biological Term Annotations	1.0	null
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70785
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16451
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
BRD-K90787403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06747
semustine-7487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE184902_3_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16267084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53492
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	1.0	2.18987
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	5.84505
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
Pancreatoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32022
protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_4500_KO_zc3h12a_DRP003625	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26411
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23269
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K20073772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47336
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80409
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18682
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54172
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95715
Ewing's sarcoma family tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13332
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39994
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60111
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5348
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47441
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
PMC10794847-mmc2.xlsx-PBRM1_KD_down-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89014570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13248
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36817
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10932
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42653
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87056
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.246
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3507
tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71315
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9587
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.404415
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49159
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08268
Lung squamous cell carcinoma_LUSC_TCGA-66-2758-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30462
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87308
KYSE450	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17034
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17723
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9838
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00256
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48065
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41512
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03985
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K12019169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69518
propantheline bromide-3013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23005
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2581
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052814
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091306
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51969
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
proteolysis	GO Biological Process Annotations 2023	1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05447
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
Chicago Sky Blue 6B-6626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.65494
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
disulfiram-5729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lacquer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
Pancreatitis	DisGeNET Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.863
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46028
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10154
BRD-K24337237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5208
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36852
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
5707885-6385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16597
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-2.65969
BRD-K88313926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21703
CRCGN017_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15297
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04011
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50615
ABCC8	Hub Proteins Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9179
COLO829	CCLE Cell Line Gene Expression Profiles	1.0	1.47349
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06002536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07541
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.277038
BRD-K65789952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34243
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HaEpi cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01008
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95417411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14558
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
15459216-TableA2a	GeneSigDB Published Gene Signatures	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0916
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.46525
IGR37	CCLE Cell Line Gene Expression Profiles	1.0	1.46145
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11857_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.23706
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13332
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090505
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.883748
naltrexone-1363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K58323923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57113
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04908
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
APH1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46543
ARID3A	ENCODE Transcription Factor Targets	1.0	null
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08167
luteolin-5004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21271
Pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.975
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4488_KO_Rnu11_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04779
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
FOXC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9445
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
NCI-H226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938147
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02989
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7778
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59464
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08929
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43278
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80359
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6103
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10157
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82818
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HOP92	CCLE Cell Line Gene CNV Profiles	1.0	1.48997
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
nimesulide-2275	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67035256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30875
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1988
ERBB2_knockdown_237_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.41118
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841983
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176386
proteolysis	GO Biological Process Annotations 2025	1.0	null
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K16621460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35393
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050965
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
14767473-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
mutants	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02564
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23782109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16565
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06533
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830952
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_16-Table_16_Information_of_genetic_instruments_used_for_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
PMC5853489__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.64118
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5895
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64889
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21779
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
effectively	GeneRIF Biological Term Annotations	1.0	null
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16316
CARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6871
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5155
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7123
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13802_KO_Mettl14_SRP286301	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18894
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K63330804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14395
BRD-K07303702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09317
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.575
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32925
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SIU7-1426-SM-4BRWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10217
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25856
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76316
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05298
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.34789
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42663584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70588
novobiocin-4569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
altretamine-3090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96398
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21221
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05942
Pedal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30011
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15486
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03803
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1381
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11011
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.545
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74475
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.14494
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7791
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.8954
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05726
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5308
PMC9949195-media-2.xlsx-5_MR_neuro-related_traits-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.56702
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31944
PMC8203678__F5	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K24230322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07512
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62082
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
models	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46568
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51748
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08641
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86415
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03052
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.75063
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50468
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
COLO829	CCLE Cell Line Gene CNV Profiles	1.0	1.34416
small intestine	HPA Tissue Gene Expression Profiles	1.0	0.853711
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864518
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.35485
BRD-K12986105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67959
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30737
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.558
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.45004
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82843
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76543
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064312
aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97447
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7384
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.16957
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3864
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50865
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1483
TFAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.477
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79878
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00337
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04414
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
Acute Myeloid Leukemia_LAML_TCGA-AB-2946-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90615
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4367
acetylsalicylsalicylic acid-1377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.111666
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70853
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2097
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58519
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
danazol-1954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932951
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54007
Perturb_12317_KD_HNRNPM_SRP136770	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.56703
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.198179
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2976
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6936
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04605
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.649297
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11848
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
posterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03127
STX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
TCF3_01_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.55159
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88722
0179445-0000-3736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
a15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15094
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
JC-06-ED36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.547912
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ModE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60217
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.26307
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9295
BRD-K17910135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22914
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_15827_OE_Nrf2_SRP291724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.21464
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084861
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31908
Oropouche fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
NCI-H1573	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41718
photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.09442
BRD-K29509140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18356
norfloxacin-1406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8153
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947889
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.804
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F3-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2B-Supplementary_Table2B_Full_results_of_the_proteome-wide_MR_in_Ukb_ppp_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93729
KA-78-TY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261753
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71907
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.440274
NB13	GDSC Cell Line Gene Expression Profiles	-1.0	-2.6137
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27915
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980606
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27664
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24073
resolution	GeneRIF Biological Term Annotations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.132812
Splenic Diseases	CTD Gene-Disease Associations	1.0	1.15324
GSE139948_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2276
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15371
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44772
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1525
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08289
SALL4	ChEA Transcription Factor Targets	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4689
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190601
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47267
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65099
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91535
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04969
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
metalloexopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72723
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
pancreas	HPA Tissue Protein Expression Profiles	1.0	2.04572
caco2	HPA Cell Line Gene Expression Profiles	1.0	0.965418
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46515
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92001
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23782
Dystocia	CTD Gene-Disease Associations	1.0	1.10353
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70693
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
a10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695354
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96745
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98075
BRD-K98437821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34618
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
carboxypeptidase activity	GO Molecular Function Annotations 2023	1.0	null
Endocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116103
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00943
C2BBe1	GDSC Cell Line Gene Expression Profiles	1.0	1.92868
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
mcf-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059891
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16177
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.50452
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
COLO775	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60011
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046372
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075836
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40668
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51252
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84153
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07386
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57797
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K87779720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06642
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2228
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05974
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55143
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15193
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.2206
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Orr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
Anthranilate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13096
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.799
transition metal ion binding	GO Molecular Function Annotations 2023	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6768
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0654
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16065
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K94205659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60004
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16467
8MGBA	DepMap CRISPR Gene Dependency	1.0	3.44948
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96488
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3393
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
LASV_FML29 _4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.98065
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830315
luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36817
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03751
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7422
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
GSE149075_1_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Proteasome regulatory particle, base subcomplex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72346
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62774
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Learning Disorders	CTD Gene-Disease Associations	1.0	1.17497
NCI-H250	GDSC Cell Line Gene Expression Profiles	1.0	2.19282
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20756
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06614
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9803
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49927
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17713
GSE236815_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.34664
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105518
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35492
UACC62	DepMap CRISPR Gene Dependency	1.0	2.14308
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932951
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06074
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.179
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.40762
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
coactivator	GeneRIF Biological Term Annotations	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54711
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03758
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30228
LTC4S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11108
BRD-K60905563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03174
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56466
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08058
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
DUSP1_Deficiency_GDS1606_765_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59472
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05138
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2461
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
edrophonium chloride-1936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FURIN_Deficiency_GDS3512_568_mouse_T-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5816
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_9-Table_9_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_coronary_heart_disease_CHD_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Body Weight Changes	CTD Gene-Disease Associations	1.0	1.01928
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28629
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.52532
Infertility, Male	CTD Gene-Disease Associations	1.0	1.17
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
hexylcaine-2708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14416602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08765
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52974
PMC5548020__F2	PFOCR Pathway Figure Associations 2024	1.0	null
C2BBE1	CCLE Cell Line Gene Expression Profiles	1.0	1.67022
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04436
BRD-K67284043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15399
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.63339
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13566
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47237
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6323
Staphyloenterotoxemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5108
calycanthine-5744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074157
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
T47D	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44166
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
Acute pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
GATA-1_KD_GDS1245_81_mouse_megakaryocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17652
BRD-K96970199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39485
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A614-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3156
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30539
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56466
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
JHU022	DepMap CRISPR Gene Dependency	1.0	3.59728
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45233
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.09182
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191449
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85033
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
BRD-K71839680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56913
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93747
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37706
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57258
D502MG	DepMap CRISPR Gene Dependency	1.0	3.15373
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26527
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969265
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07979
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.08055
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7134
Perturb_14530_KO_Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76963
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
acepromazine-2769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26233
ASPARAGINASE	DGIdb Drug Targets 2026	1.0	4.07169
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
Fetal Death	CTD Gene-Disease Associations	1.0	1.33169
dicoumarol-4323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33892
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941147
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02727
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57945
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841182
BTS	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57497
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0895
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4931
cisplatin_homo sapiens_gpl6480_gse33482	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084861
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07639
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.88753
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06414
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
RANBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70862
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054584
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2419
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00022
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06614
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68766
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
BRD-K75775113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08484
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34184
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43386
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856206
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.685903
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091557
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K81131499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33439
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.25
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67757
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8751
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059745
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
PMC8384902-mmc5.xlsx-H889_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	4.50236
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K93662118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7473
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93605
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08219
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7235
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0117
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51208
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946171
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880381
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0987
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.12835
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36319
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15031
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16082
RUVBL2	Hub Proteins Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894034
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39808
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
structure	GeneRIF Biological Term Annotations	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891675
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8165
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09749
Perturb_14700_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9285
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	3.20497
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9173
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23027
PMC3122626__F9	PFOCR Pathway Figure Associations 2024	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885602
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6313
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
BRD-K20259776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04199
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89667
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7532
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07704
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.39157
BRD-K74302837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3349
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18045
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25388
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Magnesium chelatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
autism	GAD Gene-Disease Associations	1.0	null
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19382
pirenzepine-1388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65817
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACSM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77365
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5238
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2421
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53359
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9138
crystal	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K57200567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01693
NANOG	ChEA Transcription Factor Targets	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12955
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24198
catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191071
BRD-K23241743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80541
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
zinc	GeneRIF Biological Term Annotations	1.0	null
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
NCI-N87	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42069
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32658
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1764
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7712
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SPINK1	MSigDB Cancer Gene Co-expression Modules	1.0	null
NCIH1299	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19734
Perturb_4489_KO_Rnu11/Trp53_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.83449
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
megestrol-3091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36505
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9006
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6165
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7207
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27104
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26296
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11374
MKN7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08385
folded	GeneRIF Biological Term Annotations	1.0	null
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
Exosporium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210818
PMC4598984__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02216
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99612
BRD-K63401195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76317
SLC25A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56754
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1021
astrocytes	BioGPS Cell Line Gene Expression Profiles	1.0	1.34341
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0263
CBX2_KO_GDS4445_353_mouse_E11.5 XX embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69966
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GDF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33704
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.63294
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62707
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19374
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3813
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02099
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6226
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Human - Fetal Development - L2 - Pancreas-Acinar cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.227
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
BRD-K04701596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05406
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.18093
Biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	0.88523
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72023
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
PHF8	ENCODE Transcription Factor Targets	1.0	null
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50143
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45727
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57972
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01595
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63466
BRD-K90874005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25674
CBM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4231
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69126
BRD-K27265817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72951
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647721
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
tiabendazole-4402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Endospore external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1364
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412391
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
A427	GDSC Cell Line Gene Expression Profiles	1.0	1.58535
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.34819
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048667
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.11843
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0227
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2103
VCAP	DepMap CRISPR Gene Dependency	1.0	2.80218
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841182
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
A427	DepMap CRISPR Gene Dependency	1.0	2.12688
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	2.04909
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
CE-18-CG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209414
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03386
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65141
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8613
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74101
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06054
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.01623
PMC4598984__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
meprin a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.913443
lisuride-1962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81546
inhibin a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.297713
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56058
ciclacillin-3800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tracazolate-6619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875643
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_13450_KD_Hnrnpk_SRP146257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64596
Aspartate carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22065
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841983
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837868
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5742
NO11	DepMap CRISPR Gene Dependency	1.0	2.16875
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40198
BRD-K96353852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15208
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31731
chlorzoxazone-2263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2025	1.0	null
isometheptene-3145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9006
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
PMC3470785-NIHMS377161-supplement-12.pdf-127-ZNF623_ZNF623	Rummagene Transcription Factor Associations 2026	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9215
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25334
CAL120	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24947
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bacterial-type flagellum hook	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
calu-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604099
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN011_HEPG2_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29025
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6936
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33856
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EFNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K49108064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.364
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7741
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-M13639915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02225
Midgut cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64757
Encysting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
TCF3	ChEA Transcription Factor Targets	1.0	null
TOV112D	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61459
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6802
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05326
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9547
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087425
zinc ion binding	GO Molecular Function Annotations 2023	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31203
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.101127
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43955
GNAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49127
BRD-K60716223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38505
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
OGDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.757
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.15324
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82643
KMS26	DepMap CRISPR Gene Dependency	1.0	3.77457
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6811
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828732
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998861
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PRPF38A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90368
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12365
BRD-K00381858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03844
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16982
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87010860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24286
ERG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23452
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22868
BRD-K03339354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36078
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66065
binding	GO Molecular Function Annotations 2015	1.0	null
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.10412
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ATF3	ChEA Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.45484
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80057
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37059
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40677
BRD-K50191826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34205
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42804
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13111
BRD-K37276417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20999
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077072
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71631
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1431
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17459
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63425
LB647-SCLC	GDSC Cell Line Gene Expression Profiles	1.0	2.49084
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20174
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28285
Plant parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.22696
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	3.5314
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05836
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36708
estradiol-2701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2232
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.65543
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4446
PF-01378883-00-6405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.927923
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03765
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49996
labetalol-3167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36732
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02981
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12813
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05748
BRD-K43637338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44723
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35845
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07638
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24042
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K40265664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21841
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
sulpiride-1967	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23091
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
metallocarboxypeptidase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K79376287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22364
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06537
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7078
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99156
CRCGN017_MCF10A.WT.HP_24H:K19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0584
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37471
ACSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58383
BRD-K13267130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02075
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02942
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bestcharacterized	GeneRIF Biological Term Annotations	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98333
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22081
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46915
BRD-K12936425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3437
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.41211
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.079
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00206
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055804
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.22487
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544152
BRD-K77074748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3683
Hypertrophy	CTD Gene-Disease Associations	1.0	1.35849
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
CFPAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47226
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49908
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18984
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45321
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37565
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06762
BRD-K74324157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03207
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76617
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09474
Rto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
BRD-K52688277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43233
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
maturity-onset diabetes of the young type 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
BRD-A69110666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34051
Fbt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23663
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
PMC9949195-media-2.xlsx-4_LD-pruned_SNPs_in_MR-Supplementary_Table_4_List_of_the_LD-pruned_r2_001_genome-wide_significant_variants_of_each_cis-pQTL_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
metallocarboxypeptidase activity	GO Molecular Function Annotations 2015	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06267
PIAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78495
BRD-K50961262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08221
BRD-K83818372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46762
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7373
Perturb_937_KD_Smndc1_SRP337256	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.39876
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04932
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938992
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61262
BRD-K10571481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00273
COLO680N	DepMap CRISPR Gene Dependency	1.0	2.81629
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070971
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53084
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.261
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8184
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
OS252	DepMap CRISPR Gene Dependency	1.0	2.06839
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192043
BRD-K61213827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44801
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3008
GSK3B_knockdown_206_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.51718
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A101D	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51999
Amnion epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66779
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
BRD-K28375929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00603
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38997
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04834
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956615
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.3282
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61163
Exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.776
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.427
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07479
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9538
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25803
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.74118
Chloroplast outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06345
Abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1245
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89102
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43701
BRD-K82224868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29283
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888544
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vitexin-2155	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97225
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7024
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17265
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30202
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
3-nitropropionic acid-6402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39241
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914348
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
zalcitabine-2932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88253
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02258
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61701
ATP5MK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1848
malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.670064
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77405
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
Ewing's sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61205
Gnathomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
CRCGN014_HEPG2_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36074
PMC11259242-str-55-2045-s001.xlsx-Table_S4-Table_S4_Full_results_for_all_proteins_tested_with_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61388138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01971
decreased circulating chloride level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60171
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49213
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35492
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SSB_02_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.20163
HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6398
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054188
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17379
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2541
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24169
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
Acinar cell_Pancreatic islet_Human	CellMarker Gene-Cell Type Associations	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46893
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31703
plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.784156
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56063
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-1.16313
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3197
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40677
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Peptidase M14, carboxypeptidase A	InterPro Predicted Protein Domain Annotations	1.0	null
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55878
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
Perturb_14701_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.7481
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17196
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02657
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.663
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38103
BRD-K86792405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0367
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.517321
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
BRD-A68323834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43049
BRD-K71123535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93842
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
CRCGN017_MCF10A.TP53.M_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19241
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
Osteoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04927
BRD-K75844451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31456
Posterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
GSE220520_1_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5499
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4492
LD-37-JE11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203831
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	1.40585
18321301-Table2c	GeneSigDB Published Gene Signatures	1.0	null
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11824
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0665
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25388
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21606
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2001
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878013
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.981
Perturb_4217_OE_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54396
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85523
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.840941
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.874372
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2556
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02525
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1026-SM-48TZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834893
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6262
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11978
Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66732
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57458
BRD-K50596260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2956
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50913
DLD1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.31205
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
HEYA8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41013
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35802
GSE115328_6_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6993
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14705_KO_Col1a1_SRP198671	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9664
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22214
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
photosystem i	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.52225
CRCGN014_HEPG2_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07215
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K73387470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02459
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57167
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.54183
Protein digestion and absorption	KEGG Pathways 2026	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3656
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4799
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2531
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35337
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82794
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4609
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03604
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59761
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03052
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
procarboxypeptidases	GeneRIF Biological Term Annotations	1.0	null
NIX_Deficiency_GDS2630_160_mouse_spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88745
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965347
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19993
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918714
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14925
PPARD-23208498-MDA-MB-231-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80018
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5994134__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06078
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21631
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN012_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01698
CCDC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54679
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3566
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3902
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21945
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06388
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841983
flurbiprofen-4674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841139
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060129
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.543295
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
F5 meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2038
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887476
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14658
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13949
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
protein catabolic process	GO Biological Process Annotations 2025	1.0	null
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070063
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ligation	GeneRIF Biological Term Annotations	1.0	null
BRD-K54247106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28385
GTEX-Q2AH-0926-SM-48TZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6209
Cecum mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85606
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95704
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.4104
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zinc ion binding	GO Molecular Function Annotations 2025	1.0	null
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17656
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.134
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05682
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_10705_OE_ATF5/PROX1/CYP3A4_SRP287297	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96722
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74216
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96133500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77006
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86451
E2F1_KD_GDS4094_446_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841182
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90545
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38019
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874896
BRD-K09432998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59172
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
Byssinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
used	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43652
ALMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21399
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.408699
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50391
pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.56284
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
CORL311	DepMap CRISPR Gene Dependency	1.0	2.97685
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82621
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10076
chymotrypsin	GeneRIF Biological Term Annotations	1.0	null
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1638
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21990363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00899
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5924
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4279
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12395
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75068
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2871
Perturb_4215_KO_Ezh2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.91542
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39755
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03441
BRD-K10564128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5837
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50966
molecular_function	GO Molecular Function Annotations 2015	1.0	null
abnormal lens morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938012
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01785
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A28932952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15375
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.87419
BRD-K61271364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34953
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58826
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.307004
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.499843
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095251
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8063
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K26636241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00361
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.274
irinotecan_rattus norvegicus_gpl1355_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11342
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884787
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.16782
BRD-K20253608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01244
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
SK-LU-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.24708
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.419383
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21689
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41265
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	3.54502
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71785
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10959
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3622
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
pentetic acid-5264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5099
lung adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151033
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14694_KO_Igf2_SRP111406	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.56533
carboxypeptidase activity	GO Molecular Function Annotations 2015	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484766
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.25589
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83826
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60687
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97269
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV90	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2104
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212271
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89333
genistein-6194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.307
RIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1365
Cell trailing edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
BRD-K34343777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10604
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88854
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4614
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.244
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296484
EP300	ChEA Transcription Factor Targets	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6349
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45735
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37732
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13096
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08448
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.29622
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49223
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46435
BRD-K40228218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89167
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
HUNS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7389
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.17439
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06342
amiprilose-4119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98264
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74283
Exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.954
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10155
BRD-K84233319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00665
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26548
BRD-K55510118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68988
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1885
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.863586
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13177
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
model	GeneRIF Biological Term Annotations	1.0	null
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	1.72182
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21096
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0416
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580818
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.19777
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
highresolution	GeneRIF Biological Term Annotations	1.0	null
Pleopod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
Mast cell granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31474
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.919971
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1245
Cpae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8652
WM2664	CCLE Cell Line Gene Expression Profiles	1.0	1.77572
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41314
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
IL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488199
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86354
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
PAAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88394
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K04407772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29321
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99563
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41828
Pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.427
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
BRD-K83028309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25985
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
state	GeneRIF Biological Term Annotations	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AN3CA	CCLE Cell Line Gene Expression Profiles	1.0	1.8136
harmaline-2805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11633
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35213
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7487
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20191
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.236683
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14807
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965347
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863075
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08377
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827663
AD-30-TH82_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426781
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836934
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7778
Gastric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
WD-97-SF27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224153
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12576
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.869
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
exopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19976
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21625
BRD-K18768614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55025
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02981
BRD-K13977555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26241
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17097
JHUEM2	CCLE Cell Line Gene Expression Profiles	1.0	2.33892
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66595
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56025
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39605
OE33	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30461
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80374
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.01814
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87944
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-03-MJ64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247441
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841182
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-3977	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Elongin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209248
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
JJN3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.81793
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272075
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24247
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43769
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73583
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061415
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PECAPJ49	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38622
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8685
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.71326
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.69718
RPA2	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K29379469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39106
Aedesaegypti	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16776
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4748
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13674
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55134
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044121
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.83083
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38144
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33274
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32212
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128616
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03758
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.74215
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18025
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26682
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.67028
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.876
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.649344
PA1	DepMap CRISPR Gene Dependency	1.0	2.79095
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73797
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00267
BRD-K78944047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54988
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58589
PMC9734180-41398_2022_2274_MOESM8_ESM.xlsx-Supplemental_Table_2-Supplemental_Table_2_Genes_regulated_by_TFEB_expression_are_altered_in_MAPT_p_R406W_brains_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50115
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905831
PMC5853489__F3	PFOCR Pathway Figure Associations 2024	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29228
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.76986
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01932
BRD-K04722226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26317
Radula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15284
guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.674135
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.369
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25881
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00191
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0244
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.641238
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85879
b800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.884244
Inhibin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
protein catabolic process in the vacuole	GO Biological Process Annotations 2023	1.0	null
BRD-K54948591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13873
HDAC1	ENCODE Transcription Factor Targets	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1804
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921704
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.99313
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78623
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30734
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
BRD-K01759041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15142
PRDM5	ChEA Transcription Factor Targets	1.0	null
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
bumetanide-2409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51266
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
RRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21255
FAM53B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98029
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
solution	GeneRIF Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02979
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83831
PMC11960529-mmc4.xlsx-Atrial_LHX2_KOoverCT-gene_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21409
pirenperone-5274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92231
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86855
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20631
Oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2265
changes	GeneRIF Biological Term Annotations	1.0	null
artemisinin-1714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-1226-SM-4BOPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19246
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066401
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86379
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94385
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81946
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27813
BRD-K89394474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71924
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853842
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891675
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10018
Proteinase inhibitor, carboxypeptidase propeptide	InterPro Predicted Protein Domain Annotations	1.0	null
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.42813
acute pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393374
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50064
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Scapula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
SYO1	DepMap CRISPR Gene Dependency	1.0	2.57686
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
19074828-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.902
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41537
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039989
AN3-CA	GDSC Cell Line Gene Expression Profiles	1.0	2.22576
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26757
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.393479
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64943
BRD-K46774516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2551
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120082
BRD-K43889095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73402
pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936449
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32911
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
A673	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31903
Pleural ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
PMC5548020__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909789
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50119
prednicarbate-5119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.46481
Acute pancreatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69591
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74353
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45572
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44264
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2137
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5903-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20544
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54711
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL697 (CC2D1A)	NURSA Protein Complexes	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6995
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K99609051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38786
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842947
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08563
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96398
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
pancreatic	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193329
Perturb_14529_KO_Gata4/Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13177
SH4	CCLE Cell Line Gene Expression Profiles	1.0	1.59778
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.762487
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25736
YWHAG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66729
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
MCF7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.94441
affecting	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18241
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259254
valdecoxib-6403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09376533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22222
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37372
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47237
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12932
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11997
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
PDSS2_KO_GDS3454_120_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.671
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31248
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888164
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04134
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52004
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Photosystem II reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042176
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21677
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887132
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56199
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4608
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43855
ATP6V1B1	Hub Proteins Protein-Protein Interactions	1.0	null
KE-74-OZ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28099
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72953
SW620	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47805
MacAB-TolC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01023
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03963
3-acetamidocoumarin-4426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2468
FA-52-OO58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28874
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.482
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
Digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34255
FLI1_01_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58741
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23624
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932951
promote	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
USP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94783
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2059
thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.64958
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
CHD7	ENCODE Transcription Factor Targets	1.0	null
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FTC133	CCLE Cell Line Gene CNV Profiles	1.0	1.41474
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11334
SERPINI2	MSigDB Cancer Gene Co-expression Modules	1.0	null
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01809
PIGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77893
Proteinase inhibitor, propeptide	InterPro Predicted Protein Domain Annotations	1.0	null
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875302
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33367
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87056
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0822
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11792
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82456
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19591
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55749438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09284
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37371
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207569
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
one	GeneRIF Biological Term Annotations	1.0	null
BRD-K96788889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16523
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
BRD-K47062996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02719
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55308
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0823
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
TE5	DepMap CRISPR Gene Dependency	1.0	2.31305
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436438
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.40528
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K43387144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4423
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04972
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.20152
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02899
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1033
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
COV362	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22428
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
C32	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2544
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13968
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17314
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3466
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CRCGN015_MCF10A.WT.HP_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26219
RH28	DepMap CRISPR Gene Dependency	1.0	3.40271
BRD-K39271757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77765
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.83299
Tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17802
BRD-K99824630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34787
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25714
SF767	Achilles Cell Line Gene Essentiality Profiles	1.0	1.33895
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98395
chp3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
pindolol-4496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08347
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48911
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45752
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.886
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95577
BRD-K09711841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6054
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Aphakia	DisGeNET Gene-Disease Associations	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15364
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2238
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21743103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20789
TP53	ChEA Transcription Factor Targets	1.0	null
NFE2L2_01_60	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.83451
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.949424
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4855
BRD-K38536183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44746
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	2.00905
BRD-K49745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04724
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044468
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7301
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080625
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41366
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
NuA3 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
USP7	Hub Proteins Protein-Protein Interactions	1.0	null
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95262
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7736
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5379
Fibrosis	CTD Gene-Disease Associations	1.0	1.05757
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BCLAF1_02_142	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.2854
RecFOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
PPARD	ChEA Transcription Factor Targets	1.0	null
BRD-K25269762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15573
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_3_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13096
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
Perturb_14693_KO_Sufu/Spop_SRP171166	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242672
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1576
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36955
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.074
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28466
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8786
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26881
remodeling	GeneRIF Biological Term Annotations	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06689
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.85
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43956
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49939
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47615
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0217
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47873
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43018
BRD-K05645536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4501
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.78247
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07144
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35267
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36826
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
BICR56	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70622
ESS1	CCLE Cell Line Gene Expression Profiles	1.0	1.53284
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084158
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.686028
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.782891
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5505
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9513
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840468
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34479
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72948
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82451
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836648
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.09366
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34914
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80393
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43605
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meprin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15722
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4586
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65443
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04504
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_10-Table_10_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_stroke_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
DA-88-JF21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29651
IPO13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41605
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Buccal mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34491
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
LE-40-JW92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272698
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830051
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12749580-42003_2025_9274_MOESM7_ESM.xls-Supplementary_Data_4-Supplementary_Table4_Tissue_expression_of_GWAS_and_PW-MR_genes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30545
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.06698
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62855
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.51065
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29476
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hydrolase	GeneRIF Biological Term Annotations	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.31765
PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
EE-08-SZ54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275512
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1467
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06959
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE141624_3_v_6_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98388
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98388
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39548
Woronin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
oxaprozin-4530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23035
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079186
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48872
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57019
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.589
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879544
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46012
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40861
FL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2808
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01276
496100483_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.88824
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0837
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088552
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.277038
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Perturb_16595_KD_Arid1a_SRP148113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.40648
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K45734366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01425
15548371-Table3	GeneSigDB Published Gene Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8782
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.978462
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828732
BRD-K66681850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34115
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	1.53004
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K67403750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89558
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33213
metalloexopeptidase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38544
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30725
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02899
BRD-K90744477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15359
female infertility	IMPC Knockout Mouse Phenotypes	1.0	null
Gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855525
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Replication inhibiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1495
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085149
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
fs6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93592
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27959
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22448
Poisoning	CTD Gene-Disease Associations	1.0	1.5721
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27126
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088547
D-247MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.80285
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
MFE-296	GDSC Cell Line Gene Expression Profiles	1.0	1.87644
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36449
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Middle midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.09124
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080187
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
Tripartite ATP-independent periplasmic transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01655
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7909
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43232
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
PMC6488628__F4	PFOCR Pathway Figure Associations 2023	1.0	null
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08002
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11011
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39461
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4576
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
mda-mb-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.547724
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856297
BRD-K97470305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33918
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30196
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Cloneh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22237
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1754
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53685
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8073
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10054
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.824477
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07704
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.864617
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45561
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980055
BRD-K75772012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02819
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32078
BRD-K51577368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00085
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830372
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
LIPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.663
lung	GTEx Tissue Gene Expression Profiles	-1.0	-1.08574
ProVWX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.39338
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069261
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
DAOY	CCLE Cell Line Gene CNV Profiles	1.0	1.55025
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
sidechains	GeneRIF Biological Term Annotations	1.0	null
chr7_130282658_T_C_b38	GTEx eQTL 2025	1.0	1.61541
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.639
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15242
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67217
ketoprofen-4751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35451051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28044
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870733
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85304
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27245
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.548
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
RPLP0	Hub Proteins Protein-Protein Interactions	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01972
PCBP1_02_137	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.62986
BTBD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55808
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5646
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
BRD-K32582260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18476
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0516
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81043
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.34285
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978142
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5588-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.108163
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4388
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877989
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2325
BRD-K89122173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99618
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
Perturb_16510_OE_Tafazzin_SRP284254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41946
furosemide-1580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6801
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.441426
Activin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
TC32	DepMap CRISPR Gene Dependency	1.0	2.09046
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059648
hydrastine hydrochloride-1740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0103
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112085
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25131
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
AD-70-DU18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341056
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86811
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70518
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05187
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9369
ion binding	GO Molecular Function Annotations 2015	1.0	null
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41496
D425	DepMap CRISPR Gene Dependency	1.0	3.29034
Old mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
BRD-K54066059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00333
aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K78162975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17733
PMC7462863-41467_2020_18186_MOESM13_ESM.xlsx-Suppl_Data_11-Supplementary_Data_11_Driver_genes_NOT_found_in_the_Mongolian_cohort_compared_with_previous_HCC_studies_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63270352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49082
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_3_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type II protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46736
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO320	DepMap CRISPR Gene Dependency	1.0	2.43693
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40396
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69134
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32176
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61421
HCE4	DepMap CRISPR Gene Dependency	1.0	3.15826
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
GSE135350_2_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935612
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42666