association	dataset	threshold value	standardized value
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14773
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75589
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05513
Perturb_12219_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6678
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09833
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64526
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01044
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6811
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447306
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL1-OVERLAP_GENES_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
km3	HPA Cell Line Gene Expression Profiles	1.0	1.21834
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050343
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975998
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907457
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.21
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.9273
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.961578
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29076
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.4189
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00011
CRCGN011_HEPG2_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2653
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	0.921076
OS-RC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_02_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59067
ventrolateral part of alar p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01427
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874225
QE-93-PG25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216674
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03045
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17385_KD_Smyd5_SRP014021	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55583
PMC10913870-pr3c00632_si_001.pdf-84-ZC3H8_ZC3H8	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991323
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29352
Lung squamous cell carcinoma_LUSC_TCGA-39-5027-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266982
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6097700-pgen.1007515.s007.xlsx-S1_Table-S1_Table_SATB2_NuRD_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72127
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877659
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3805
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8013
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925594
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55717
MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.39906
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19223
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.33249
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11325
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.05292
RI1	CCLE Cell Line Gene Expression Profiles	1.0	2.79856
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5809
TET1	ChEA Transcription Factor Targets	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6456
CRCGN014_HEPG2_3H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2793
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10807933-NIHMS1954791-supplement-4.xlsx-Bag6_KD_proteomics-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19014
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13699
hsa-miR-3973	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01407
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992506
FOXA2	ENCODE Transcription Factor Targets	1.0	null
Perturb_9602_KO_Eed_SRP328167	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	302.936
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34395
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.933771
cellular response to calcium ion	GO Biological Process Annotations 2023	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.69638
anterior	GeneRIF Biological Term Annotations	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960836
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514955
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.988047
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EBC1	DepMap CRISPR Gene Dependency	1.0	2.67371
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157233_1_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6330_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1255
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5744-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00545
MHH-CALL-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11519
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53837
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08364
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.043458
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5653
LD-69-ZV56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490852
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319498
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.49777
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914048
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.5297
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7589
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.762128
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02167
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.35623
NB4	CCLE Cell Line Gene Expression Profiles	1.0	1.5292
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925937
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05026
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.32064
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.7301
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98606
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01238
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Signal recognition particle, endoplasmic reticulum targeting	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81721
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64618
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04143
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5839
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Regulatory T (Treg) cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5939
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.321
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11656
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GE-47-OO30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287362
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22685
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05671
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23458
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55696
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3466
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4361
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871029
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5941
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873598
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1534
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05095
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03149
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9342
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.13036
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16962
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93402
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.618
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.984902
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	5.34798
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959617
dbtrg05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.863201
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270245
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0366
MG63	DepMap CRISPR Gene Dependency	1.0	2.20429
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54947
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRC_overexpression_276_GSE37428	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.65998
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05661
GSE210682_0_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26611
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987613
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.49204
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38161
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.922585
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.636
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60087
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.976712
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01427
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24117
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6913
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22436
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.366
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27363
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05372
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6466
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04985
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0826
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10945
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00947
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9589
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57232
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus reuniens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848703
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.976
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833365
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8164
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.10564
CRCGN014_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71478
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70698
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447381
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989694
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98356
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42467
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02292
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824821
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0779
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0498
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	1.63054
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.988147
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10319
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.45415
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204787
BV173 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21211
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_12096_KD_Tsc22d1_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4169
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56847
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17817
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3626
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.47185
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00414
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51576
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2014
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953375
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838598
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB5_CREB5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.873444
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06576
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826588
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07034
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copine	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01382
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2497
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91281
16042785-tableS4	GeneSigDB Published Gene Signatures	1.0	null
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15372
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0631
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75513
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835451
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17312329-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30651
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32709
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13236
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1023
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9913
E2F4	ENCODE Transcription Factor Targets	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856457
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.588831
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1144
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.907
MYC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5527282-ncomms16041-s3.xlsx-M_LPS_-_gene_signature-Supplementary_Data_2_Full_gene_list_of_M_LPS_-_signatures_as_defined_in_figure_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12188
AM38	DepMap CRISPR Gene Dependency	1.0	3.84566
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19525
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04991
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292932
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01852
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.44754
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02976
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
haptoglobin-hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
DE-99-OT37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380193
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05269
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08284
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.24725
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.246424
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1007
Lung adenocarcinoma_LUAD_TCGA-49-4510-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68691
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYCBP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1824
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3683
PAPA syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.33249
Perturb_14865_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.04011
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08294
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.47986
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P31FUJ	CCLE Cell Line Gene Expression Profiles	1.0	1.47973
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4026
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01487
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BF-19-KU00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541922
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.892702
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0747
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCOR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
REH	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.00691
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49507
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4244
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7415
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50477
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.56676
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.063
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.34269
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7375
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37547
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3095
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA-90-RU33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221933
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.58382
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20222
von Willebrand factor, type A	InterPro Predicted Protein Domain Annotations	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.37609
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34388
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01347
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901841
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MF-81-RJ18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.649848
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12988
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28638
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9162_KD_YBX1_SRP346212	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147207
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-1.45877
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34501
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882699
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
SOX2-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Phosphopyruvate hydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07792
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8373_OE_AC093797.1_SRP344034	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4641
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918241
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9103
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13634
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247132
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.970793
IKBKG	Hub Proteins Protein-Protein Interactions	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8888
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19872
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336215
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_SOX2_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825411
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REL	JASPAR Predicted Transcription Factor Targets	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9888
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.7617
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05598
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945055
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6564
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925555
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3782
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92822
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03678
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4381
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JIMT-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.64236
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26232
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.719758
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8610_KD_Camta1_SRP048702	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78335
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41192
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960836
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.559
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835918
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.4842
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886057
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	3.55734
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57758
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6444
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230345
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02808
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852158
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.16433
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327643
KATOIII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89205
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11869
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921674
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385911
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	0.878887
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9842
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.144
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49284
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08378
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906971
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13307
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9257
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11785
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45712
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01166
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829806
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851718
reticular formation of basal m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09838
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846912
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.12544
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843012
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3197
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7382
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01867
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	294.785
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0885
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05564
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37636
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6811
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0257
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.306
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.14747
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890854
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04056
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	2.15835
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6315
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6045
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03353
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6531
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9331
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8856
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03347
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94545
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9061
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834648
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68234
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Complex of collagen trimers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
TCF7	ChEA Transcription Factor Targets	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.75063
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Legume allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Perturb_13390_OE_NSD2_SRP199225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56422
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976741
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49433
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-SOX2-M_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.69128
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61085
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02839
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.15686
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.7604
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82629
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KYM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91137
Perturb_7464_KD_U2SURP_SRP126064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.0612
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.03394
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545475
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849805
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1535
GTEX-S4UY-0226-SM-3K2AP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14295
Perturb_13923_KD_DDX5/DDX17_SRP335223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68577
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982285
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1234
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1013
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4884
GSE114992,GSE114993_8_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26335
SPI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05458
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03932
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06588
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.051
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0346
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95765
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17215
MYBL2	ENCODE Transcription Factor Targets	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65089
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38867
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-62-ZF67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212872
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
AA-69-TD29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346018
Hepatoblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Promyelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97908
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.868683
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-SNAIL_DN_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51369
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58945
TFAP2A	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25708
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87672
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35275
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859849
S117	CCLE Cell Line Gene CNV Profiles	1.0	1.85041
Perturb_1206_KO_Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.69765
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cdx2_21074721_jejunum_epithelium_lof_mouse_gpl10773_gse23436	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.04547
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01378
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
AML193	CCLE Cell Line Gene Expression Profiles	1.0	2.22835
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.185
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.15659
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.04201
OSRC2_KIDNEY	CCLE Cell Line Proteomics	1.0	2.56233
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1602
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.163
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05301
thp1	HPA Cell Line Gene Expression Profiles	1.0	1.42235
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.73296
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	335.294
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12754
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.47391
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7569
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14659
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RH30	DepMap CRISPR Gene Dependency	1.0	2.64023
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37239
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2958
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02646
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31004
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53695
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31523
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842652
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0039
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42467
GTEX-U4B1-1726-SM-3DB9F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91255
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
Harderian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
all	GWASdb SNP-Phenotype Associations	1.0	0.030634
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91871
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
central layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79291
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41966
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15565
GSE112995,GSE132079_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056152
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1548
E2F4	ChEA Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	2.8195
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13726
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.96296
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14321
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9079
Perturb_16629_KO_Kir4.1_SRP133512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.19652
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34263
hsa-miR-548k	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98889
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03421
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0074
MC116	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82569
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832661
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245781
PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.073
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951362
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843393
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07247
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06684
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320092
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49499
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2897
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.29146
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8852
KDM4A	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.996593
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20264
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.0189
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10434
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.835
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
19904269-ST1	GeneSigDB Published Gene Signatures	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.866293
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.174
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3351
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5207
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120336_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01829
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11329
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84048
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_down-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31523
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32709
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44141
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919528
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960836
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.911702
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10668
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11013
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1128
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962309
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72948
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.90683
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57619
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.327
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3453
AE-07-IZ32_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256321
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31232
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15438
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.54693
PMC12080872-pone.0323227.s004.xlsx-All_3_C-D_YY1_dep-Gene_name_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE85995_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5201
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53158
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.827
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.705
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7481
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0335
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876132
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6909
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40819
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37389
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17303_KO_Tam_SRP126482	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.18322
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987537
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16746
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27737
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07198
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3677
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37389
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873235
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31368
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11661
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18725
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8598
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30475
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.701477
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73428
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998408
PMC3419980-leu201249x4.xls-All_expression_genes_RUNX1ETO-All_differentially_expressed_genes_with_more_than_2_fold_in_at_least_one_day_set_and_correlate_with_RUNX1_ETO_peaks_genes_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30435
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.742
BAG3	Pathway Commons Protein-Protein Interactions	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69477
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632388
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890497
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19245
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.07376
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30126
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49077
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871962
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.1105
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6879
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416333
Perturb_13062_KO_Actb_SRP293695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.9939
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17265
BICR6	DepMap CRISPR Gene Dependency	1.0	2.00874
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320721
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761039
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50445
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960836
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14154
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051914
CRCGN008_HEPG2_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24775
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13141
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869885
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502633
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67199
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.95564
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623618
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2_01_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.15521
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01659
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45275
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514864
YSCCC	DepMap CRISPR Gene Dependency	1.0	2.9226
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CDKN1A	Pathway Commons Protein-Protein Interactions	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2365
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89199
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876424
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887312
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.978208
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990828
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15614_KO_Gaa_SRP277449	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208577
hsa-miR-4445	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23027
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DE-58-OW37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271387
JARID2	ChEA Transcription Factor Targets	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972249
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.40149
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43728
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927013
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959503
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6095_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.069
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41486
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.20111
Gonadal endothelial cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2109
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916781
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4926
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270127
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43667
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3003
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55339
SARS-CoV MA15_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53836
PMC7680901-Table_6.xlsx-both_up_GSE117165-SETBP1_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.403
GSE148692,GSE148695_1_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45875
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05506
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7656
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-745A cl. DS19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
MHHCALL4	CCLE Cell Line Gene Expression Profiles	1.0	2.18565
Perturb_1173_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.8306
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45165
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156913
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0594
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01941
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21961
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2911
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0507
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMRC20_KIDNEY	CCLE Cell Line Proteomics	1.0	2.40513
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4174
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACTB	Hub Proteins Protein-Protein Interactions	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6213
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.533
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24982
Perturb_6343_KI_MCK_SRP353443	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19868
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20569
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.1588
CLPP_KO_GSE40207_380_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4554
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02975
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99074
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05297
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.114068
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	3.40322
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978621
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982701
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894475
KC-17-YN77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.522109
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10174
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9694
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27742
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16693
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13392_KD_NSD2_SRP231443	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.38237
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10161
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00323
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
GSE206784_2_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8535_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.77851
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-2.3982
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0398
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03925
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942146
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189772,GSE189773_0_v_5_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.73315
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19587
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10131
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301823
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71654
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.33249
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0309
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30613
CRCGN008_HEPG2_24H:C15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64785
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39352
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343921
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14383
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.14234
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855796
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.26855
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9322
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	242.765
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29781
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38128
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25324
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
Perturb_1430_KO_Adm2_SRP399375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.38445
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3025
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3569
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26544
Perturb_10034_KD_PUF60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.02071
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
UBE2M	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83793
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9018
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-2.88412
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890555
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7273
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59492
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8205
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Robust nucleus of arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62598
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60401
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07114
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26684
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831387
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.453
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10668
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2162
5-8F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.78388
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.50645
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BY-01A-31R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5361
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.540683
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_16363_KO_Cryab/Hspb2_SRP055864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.98011
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4355
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345843
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382618
SMAD2	ChEA Transcription Factor Targets	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4429
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265589
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.989931
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40809
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12361
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60266
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dcp1-Dcp2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.15458
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15959
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04856
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928336
interleukin-2 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9107
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.036806
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930557
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26247
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10094
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.2778
PRKAG3_Mutation (R225Q)_GSE4067_390_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNA nuclear export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5181
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.009
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55456
CCNT2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02579
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847929
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27838
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7243-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601294
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210476
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-8568-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.31054
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51125
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6557
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976594
GDM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4877
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0334
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.16995
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.79542
REST	ENCODE Transcription Factor Targets	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19964
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91765
neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
NCIH747_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.49195
Perturb_1179_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.7684
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201217_3_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2177
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QE-18-WG07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355947
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824193
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08454
RUNX3	ENCODE Transcription Factor Targets	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.91
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33803
UBTF	ENCODE Transcription Factor Targets	1.0	null
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35743
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20743
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.12709
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08747
PMC6888893-41422_2019_228_MOESM9_ESM.xlsx-DEGs_of_HEC_aEC_RUNX1-aEC_CXCR4__genes_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69266
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.25
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1864
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.584493
Perturb_1178_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2721
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7505
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57901
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19164
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997437
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47474
PMC11563688-jci-134-173448-s017.xlsx-EC2-gene_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71354
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.01382
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01082
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838473
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.869401
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7932
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7979
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14971_KD_Crebbp_SRP154933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.56967
NB-89-OV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416157
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1746
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-2_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
DNA recombinase mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.54341
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34019
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5395
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919667
GSE126402_5_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1107
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978412
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5496-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.85898
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9929
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LAN-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50018
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6222
Obesity_Adipose tissue_GSE4692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.10043
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.595662
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00072
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320682
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33585
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12673
S0-EE-Y96T_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293993
TOLEDO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78704
TGW	DepMap CRISPR Gene Dependency	1.0	2.04722
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70365
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.47974
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SS-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17249_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34503
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14568
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-508-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.507918
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32286
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5354
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.6766
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.283
Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12121_KO_Aire_SRP250736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.8794
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05361
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.64533
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753895
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50477
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69415
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.9692
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52882
Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9533
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00447
HS695T	DepMap CRISPR Gene Dependency	1.0	3.15751
TCCPAN2_PANCREAS	CCLE Cell Line Proteomics	1.0	7.86098
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02432
AE-71-CB15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.747171
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.27681
Perturb_13484_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.04003
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.87354
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_2021_Mut_Ikzf3_SRP308042	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1025
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14179_KD_TP53_SRP200529	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.21557
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.19161
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21517
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9867
MYC	ChEA Transcription Factor Targets	1.0	null
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30058
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_7_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SH-EP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27251
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	1.21075
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95995
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8061
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928864
SARS-dORF6_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70012
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6425_KD_LOC646329_SRP220725	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.30106
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF576	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06302
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00151
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1071
Perturb_11947_KO_IRF4_SRP096865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.19744
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895738
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46272
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.983529
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1289
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.3854
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20478
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liminal part of alar p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01378
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938833
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38936
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10852
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42323
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16309
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204636
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49363
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08835
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1453
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5248
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893495
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04504
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884902
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.0385
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.277
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71075
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5692
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44853
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49982
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93371
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18932
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MY-M12	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.21747
OVMANA	DepMap CRISPR Gene Dependency	1.0	3.32117
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus taeniae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0047
GI-LA-N cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64899
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36231
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN45	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.53063
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.66199
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45458
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
JUN_KO_GDS4205_294_mouse_B lymphoid cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23959
Perturb_9129_KD_KDM2B_SRP359233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.3818
PL21	CCLE Cell Line Gene Expression Profiles	1.0	1.76754
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2931
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.914696
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841009
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846066
Perturb_8537_KO_Notch2_SRP152804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28707
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.945523
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88483
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.5509
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.479
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15746
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6533
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0106
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42715
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226086
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1073
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33213
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33955
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26684
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50226
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07396
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2797
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970011
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.75571
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8601_KO_Pyk2_SRP285527	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76719
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70613
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247528
Perturb_17144_OE_Xbp1_ERP110244	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.35255
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60824
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34473
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7901
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.372
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4331
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55181
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13371
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-6_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98091
Parkinson's Disease_Substantia Nigra_GSE7621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40401
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.56945
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911961
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.41073
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9419
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86169
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36167
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934805
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.989639
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15177
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3278
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27496
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.706386
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999163
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.087
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAG3_KO_GSE4063_389_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3037
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852214
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.967844
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UMUC9	DepMap CRISPR Gene Dependency	1.0	3.07291
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08355
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200159_1_v_0_setd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19461
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41299
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99864
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6888
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SW480_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	8.08512
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59465
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27381
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41118
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08076
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	2.32894
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915584
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13583
Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17192
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5012
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04789
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826261
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03753
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896708
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25102
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827287
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.21855
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29585
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82407
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2246
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.93736
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47233
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95035
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0351
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.37822
GTEX-T6MN-0226-SM-32PMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900846
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76855
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902623
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05467
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5308218__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055361
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.7431
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00353
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.50486
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
18440302-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BE-89-DG86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210893
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14097
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26611
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3428
lateral part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15182
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50443
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13293
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41234
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cingulate	GeneRIF Biological Term Annotations	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.6786
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3843
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06497
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52086
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.26371
GSE202434,GSE202438_8_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47986
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5485-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.52863
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04353
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09686
GSE156923_0_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329947
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11045
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79876
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981116
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07196
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.842455
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.91004
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Perturb_11120_KO_Erg|Fli1_SRP402910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.752
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19758
CRCGN017_MCF10A.TP53.M_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09508
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853704
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298524
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.05015
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27008
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38408
KYO1	DepMap CRISPR Gene Dependency	1.0	3.05089
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64842
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_14615_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.3019
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15656_KO_Cyp26a1_SRP334433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.53541
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09821
HCC1937	DepMap CRISPR Gene Dependency	1.0	4.39225
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KMBC2	DepMap CRISPR Gene Dependency	1.0	3.73251
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8621
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28952
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.693925
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3629
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24939
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.87565
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42996
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3897
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74931
KASUMI2	CCLE Cell Line Gene Expression Profiles	1.0	1.52515
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7927
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37398
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Perturb_18111_KO_Eed_SRP132909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.00382
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7889
GSE216538_7_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845093
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92622
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20539
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967133
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5078
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44847
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16351
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18126
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66626
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0403
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.996
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15792
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08505
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857555
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934822
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8544
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930883
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6322
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83838
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9812
PMC9314667-Table_1.xlsx-Regulons-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_5_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13712
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81715
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.232
Fatty Liver	CTD Gene-Disease Associations	1.0	1.46621
Perturb_10936_KO_Oxr1a_SRP102450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.14727
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07308
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE186633_1_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1251_KO_MED1_ERP116563	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.30874
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8388
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.293
Perturb_12192_KD_HPRT1_SRP259972	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08965
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42283
AB-01-NB05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20407
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8018
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4974
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69842
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56883
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41595
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19831
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.984127
Perturb_11977_OE_Ifng_ERP109050	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.35116
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272121
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5787
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09945
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67251
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.9238
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6655
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.35213
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.02466
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984767
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889134
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35292
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RUNX1	ChEA Transcription Factor Targets	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.855791
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.85439
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35829
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851312
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71422
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43208
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92774
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05326
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04668
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37278
Primary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00239
Perturb_10867_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97746
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38083
HT115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82801
5637	DepMap CRISPR Gene Dependency	1.0	3.00891
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211247
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7076
chr16_57084496_CG_C_b38	GTEx eQTL 2025	1.0	1.34181
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.170747
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.105
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827788
TIA1_KO_GSE54418_264_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.23504
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15968
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.76343
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17658
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.02844
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.886434
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8943
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93244
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
L363	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85855
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21828
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916623
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55199
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21486
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1085
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mccoy	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1651
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08208
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859982
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2025	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
Perturb_1205_KO_Sp2/Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.7862
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18512
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57024
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.099248
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949129
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.34944
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415924
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01981
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11401
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03933
Hypertrophy	CTD Gene-Disease Associations	1.0	1.51255
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10223
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15463
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17345
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30773
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.654766
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78291
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8675_KD_ZNF281_SRP251817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.45701
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22532
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.63419
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20015
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.021
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5666
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960892
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8911
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21665
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1886
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956736
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.63072
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06946
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61572
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.105
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31523
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.81377
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A253	DepMap CRISPR Gene Dependency	1.0	2.28175
GSE117212,GSE117214_2_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31637
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.85022
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2015_KO_Slamf9_SRP199215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4024
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950109
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15087
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60408
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_5_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.66689
PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_DN_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.13758
Perturb_13243_KD_Lnc956_SRP345092	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25287
Perturb_1229_KD_HNRNPK_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.2385
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66296
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23674
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38916
PMC8490503-thnov11p9519s3.xlsx-Proteins_High_MLL-Gene_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31842
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.938839
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00655
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9968
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_7_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
HLE	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04145
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5939
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5226
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.099605
PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-YOUNG_NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10062
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6359
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01941
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.42556
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11408861-mmc2.pdf-9-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991885
S100A16	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.21989
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3299_KO_Bmpr1a_SRP116199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06695
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.25
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06125
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06929
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7753-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0378
PRKAG3_KO_GDS1398_703_mouse_gastrocnemicus muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985213
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974525
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
angular gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.951889
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08108
PMC6811978-main.nxml--Colon_CCD-18Co_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08251
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841044
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74948
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840356
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826169
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.044752
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.0297
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02917
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
18410693-TableS14	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE200839,GSE233826_5_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11019
Atherosclerosis_Aorta Smooth Muscle Tissue_GSE1560	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.46989
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2484
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16563_KO_Atf4_SRP320716	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534202
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98867
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952828
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06004
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42614
BB30HNC	DepMap CRISPR Gene Dependency	1.0	5.12306
GTEX-WH7G-2226-SM-3NMBN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909673
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553055
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.574832
ATM_knockdown_113_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65336
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38026
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12417
NCI-H2795	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.22668
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93454
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.7874
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245642
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12419
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.985242
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.65478
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30026
C8166	DepMap CRISPR Gene Dependency	1.0	3.73417
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.02188
TRIM28	ChEA Transcription Factor Targets	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.99302
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57592
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832714
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04068
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
ASXL1	ChEA Transcription Factor Targets	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.445
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924084
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986369
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932249
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10442_KO_Zfhx3_SRP187824	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.1596
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cornu ammonis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09474
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to calcium ion	GO Biological Process Annotations 2023	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CC-70-BD07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230568
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3411-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC905	DepMap CRISPR Gene Dependency	1.0	3.12263
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6216
stomach	HPA Tissue Protein Expression Profiles	1.0	1.33249
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Perturb_5677_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.93747
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979752
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41003
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AA-45-AA67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316763
Perturb_16556_KO_Usp39_SRP317794	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.09325
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893235
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.39366
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892869
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.51295
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8632_KO_Sh3gl1/Sh3gl2/Sh3gl3_SRP082219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.93137
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.867331
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	2.96646
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25501
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451832
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC78	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8418_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.69151
CP21R7_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163532
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07925
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4730-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.880957
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84311
AA-56-JY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223211
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160077,GSE160084_2_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236011
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928673
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36572
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247365
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16541
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85167
ST486	CCLE Cell Line Gene Expression Profiles	1.0	1.91887
EB-55-VD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304595
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17591
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03341
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852699
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07896
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4124
SKIL	Pathway Commons Protein-Protein Interactions	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30046
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7484684__F5	PFOCR Pathway Figure Associations 2023	1.0	null
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1276
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7842
Perturb_8677_KD_KLF11_SRP044756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01595
Perturb_6704_KD_LPA2_SRP057199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.62949
Perturb_6379_OE_C1QL1_SRP239013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Aiolos_NULL MUTATION_GDS3473_572_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.36505
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1372
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.11153
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.57531
LU-165	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.89688
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_13141_KO_Ctr1_SRP165861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.06254
GSE239844_8_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08086
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980225
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25523
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.282
Perturb_9508_KO_Cd1d_ERP106455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.73519
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13699
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.42113
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4283
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.07255
USF1	ENCODE Transcription Factor Targets	1.0	null
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231512
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79371
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_12558_OE_Aire_SRP033579	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.1024
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7484684__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2669
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4464
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03591
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.1261
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7711
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NALM1	CCLE Cell Line Gene Expression Profiles	1.0	1.3706
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9025
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19286
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74562
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4072
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40101
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.5484
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24128
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31593
Perturb_6638_KO_IKZF1_SRP139731	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.1759
YC-45-JD42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209283
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7374
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7285
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20404
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18699
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.44281
bleomycin_mus musculus_gpl1261_gse25640	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54101
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33551
SUPT11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7672
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
VACO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.662
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63014
2313287	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92445
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0203
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31586
TE9	CCLE Cell Line Gene CNV Profiles	1.0	1.74173
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28322
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19376
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2581
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37693
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.32801
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342836
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837552
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04058
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63923
high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
Perturb_14143_KO_Cblif_ERP002279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.06776
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86089
BB-77-QQ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264037
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15649
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976294
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8355
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5725
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLT4_knockdown_103_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72628
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0869
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54508
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.683
SUPT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61859
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20723
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.70343
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.875417
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9592
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04666
Perturb_15192_OE_LEF1_SRP406316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.52416
Perturb_13183_OE_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.81677
OCILY3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.44171
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37015
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.016
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10671
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6342_KO_LONP1/ATF4_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.11385
Lung adenocarcinoma_LUAD_TCGA-50-5933-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188814,GSE188854_0_v_1_wtap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133329_1_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87877
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02808
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28287
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09812
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.59562
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20968
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.976583
SNU308	DepMap CRISPR Gene Dependency	1.0	2.40323
Perturb_7871_KD_PCF11_SRP258098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.09357
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4478
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11436
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69607
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18215
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-680N	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.25107
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56698
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895393
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5502
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Azurophil granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4974
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23932
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6019
BCP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51494
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1114
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.19209
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8944
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848147
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2668
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916018
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10621
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.24143
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Fruit allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35838
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.4426
CRCGN009_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11724
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997596
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.941337
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6864_KO_CDK8_SRP299261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Medial dorsal nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00568
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4954
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18888
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48633
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.38673
CRCGN014_HEPG2_3H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12491
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894475
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.554642
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847932
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980941
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25164
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12518
caki2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
MYB_01_102	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.05787
FOXO3	ChEA Transcription Factor Targets	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59064
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19345
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11383
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chp126	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9762
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03987
FOS	ENCODE Transcription Factor Targets	1.0	null
vincristine_homo sapiens_gpl570_gse7556	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02845
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925887
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225854
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95604
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.0132
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897175
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.33632
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75526
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.537917
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart  (day 12.5 C57Bl/6)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23329
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74327
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	2.16926
CC-70-BD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328651
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985839
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50593
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953501
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cancer	GWASdb SNP-Disease Associations	1.0	0.561299
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21317
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.09488
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39618
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955353
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214928
disease	GWASdb SNP-Disease Associations	1.0	0.023867
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5615
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
MSTO211H	CCLE Cell Line Gene CNV Profiles	1.0	2.35833
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.163015
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15829_OE_Nrf2_SRP291727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.6051
CRCGN009_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33793
GSE217378_1_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926874
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478918
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943991
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09444
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.05788
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03986
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26956
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58359
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05759
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.04239
Perturb_10196_KD_FCircAE_SRP180885	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6599
MECOM	ChEA Transcription Factor Targets	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23001
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09015
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49638
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.09786
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26973
TFAP2A-35110662-HEPM-HUMAN-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.1617
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21182
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860648
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	6.58586
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.664
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27511
been	GeneRIF Biological Term Annotations	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1826-SM-4BRVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29631
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41218
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66235
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09444
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916461
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6326
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58809
insulin-like growth factor binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73792
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36114
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.7693
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1604
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TALL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5408
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37389
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862428
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42371
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956736
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28638
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055808
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51107
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62683
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44186
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3673
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940811
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
cellular response to metal ion	GO Biological Process Annotations 2023	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)MA_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.878
20068109-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00858
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10388
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831282
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1391
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01188
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9229
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834756
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09058
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51567
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.266912
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08404
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51605
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17353
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28841
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2317
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92061
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953578
Perturb_9752_KO_Rnf20/Rnf40_SRP228497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894876
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.7374
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to salt	GO Biological Process Annotations 2023	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41535
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54785
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306242
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04997
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309491
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SKMM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87063
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907596
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0705
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23378
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51508
Perturb_11252_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.9625
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4232
NCIH2106	CCLE Cell Line Gene CNV Profiles	1.0	2.09876
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
WM278	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.22267
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829975
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.915943
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882241
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33163
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05505
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9098
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-84-BQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276318
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.74315
Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0652
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254911
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26146
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00282
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85495
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8456
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65375
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.365
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4174
cancer	GWASdb SNP-Disease Associations	1.0	0.037285
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-94-WO47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228463
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01473
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96299
PMC4431731-pgen.1005211.s002.xlsx-ERG_TRISOMY-Unnamed_2_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03099
AURKA_knockdown_89_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.04714
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.992
Arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.29466
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2668
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836677
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0999
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.105
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32539
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.29201
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0617
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.782708
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0675
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29175
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990203
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33768
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2375
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41632
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57657
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-FDR_0_05_logFC_2_RPKM_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0188
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.27535
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
differentially	GeneRIF Biological Term Annotations	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00327
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956161
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07807
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.498066
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828708
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-18-KF56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254966
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98739
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BB-74-RX30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416576
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24555
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.019
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200597
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MTF2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.56186
KMS18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54717
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862921
TEAD4	ENCODE Transcription Factor Targets	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-73-HJ84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.678492
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19477
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.47573
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
16288205-GeneTable3	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07397
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201684
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62263
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27256
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00755
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965089
Lung adenocarcinoma_LUAD_TCGA-67-6215-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1435_LUNG	CCLE Cell Line Proteomics	1.0	2.53195
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826148
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54193
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.45221
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08139
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79421
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.09613
TAF1	ENCODE Transcription Factor Targets	1.0	null
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885452
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43319
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.088
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8561
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11569
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15372
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343649
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2291
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3808
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04339
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8554
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14458
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06431
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.827429
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-HEP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DE-73-JX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335956
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835834
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4496_KO_Hnf4a_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4033
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925655
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TERF2IP	Pathway Commons Protein-Protein Interactions	1.0	null
A_CA_04_2009_7dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70321
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6083
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877734
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.11874
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854996
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.24076
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2O	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13679_KD_TFEB_SRP033784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68095
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0372
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32701
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6459_KD_LKB1_SRP094725	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04249
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906971
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.7935
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57659
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57954
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07041
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10445
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28143
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12848
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04447
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306568
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57559
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6213
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40907
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46709
TCF3	ChEA Transcription Factor Targets	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29674
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82669
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973137
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01219
KMS20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69154
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYB_01_48	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.43525
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01927
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.782
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36687
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	0.808536
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3701
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aMEF-2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.80779
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1417_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.23148
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9761
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC95	DepMap CRISPR Gene Dependency	1.0	3.23518
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.79999
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE-73-XV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245451
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8428
MOTN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53545
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865894
PHF8	ENCODE Transcription Factor Targets	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.008
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906067
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94248
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5617
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11155
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.42699
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9718
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05675
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20663
MM426	DepMap CRISPR Gene Dependency	1.0	2.72223
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66259
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872804
RL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51747
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49611
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.53786
HC-11-RK51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388387
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60865
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1685
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.228
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.386
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IGR1_SKIN	CCLE Cell Line Proteomics	1.0	4.93884
Mevalonic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16511_KD_PAX9_SRP300302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
hsa-miR-4717-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28246
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414224
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480347
KU812	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60471
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.07681
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02928
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.05612
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828942
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02703
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04244
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02822
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.56494
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19164
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543634
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7713
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981613
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20259
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40055
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.996008
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71453
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0339
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.66418
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11685_KD_CDKN1A_SRP158041	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.685151
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SUPM2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.65928
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09346
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38509
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25058
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967193
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JA-85-SW39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287947
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11957
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6603
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1995
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7312
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8746
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.90799
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7472
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54438
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221981
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220933
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49524
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.51509
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04864
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-0.899845
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842673
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7791
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976594
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322357
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31795
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04457
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86652
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29952
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894475
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16635
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271446
SW948	DepMap CRISPR Gene Dependency	1.0	3.51476
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8813
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.20714
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06574
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08514
Necrosis	CTD Gene-Disease Associations	1.0	1.33494
Perturb_13950_KD_IGF2BP1_SRP291708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.67846
Perturb_7914_KD_TOP1MT_SRP372079	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33969
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50424
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09555
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42006
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15867
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877883
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCC2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50624
GSE211224_2_v_0_donepezil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.536266
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42698
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59879
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02733
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07892
Perturb_1795_KD_Bud13_SRP168625	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.78077
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4042
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43405
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
LE-48-SO37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204997
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.998699
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82394
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.20394
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946079
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCC2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.61106
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13657_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.53992
GSE199543,GSE239447_0_v_6_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328833
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29895
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14731
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70875
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.5958
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13549
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7459_KD_ICE1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.058
Perturb_8696_KD_Sam68_SRP373391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0251
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibrinogen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10829
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862388
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889729
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.69237
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.66168
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33873
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.166
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83042
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.958806
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.481654
Bone marrow cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45659
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252919
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RASIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02225
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BE-28-WW67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281903
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.90892
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Perturb_17410_KO_Kat7_SRP346205	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.71679
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893846
A549_Lapatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131665
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.529
Perturb_6258_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.7959
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83738
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.703
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5332
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.87031
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54794
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.912756
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76507
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.7301
Rectum adenocarcinoma_READ_TCGA-EF-5831-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55379
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13528
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674392
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92892
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06818
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.83016
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259992
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34014
cellular response to calcium ion	GO Biological Process Annotations 2025	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35482
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45404
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.24438
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934495
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19062
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.35532
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935782
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr16_57123917_TC_T_b38	GTEx eQTL 2025	1.0	3.58441
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831357
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24683
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44046
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03876
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57901
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.42703
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05269
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_3797_KO_BRG1_SRP165661	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846016
RBBP5	ENCODE Transcription Factor Targets	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43904
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76419
chr3_194353750_G_A_b38	GTEx eQTL 2025	1.0	1.45304
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.126563
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08084
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12922
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6141
ACHN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04779
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.0889
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15276
Kidney Chromophobe_KICH_TCGA-KL-8331-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC202	DepMap CRISPR Gene Dependency	1.0	2.0197
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DE-98-FC24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326145
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20905
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47478
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
p107_Deficiency_GDS3176_606_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.725311
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21544
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Subiculum, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00442
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932223
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.5709
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.97796
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25893
Perturb_16407_KO_Vgll2_DRP005135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.684
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.76153
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877092
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6950-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225928
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_12218_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DDOST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25617
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846654
Peanut allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5921
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917527
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870309
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59268
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25914
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.999761
Perturb_8709_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.69166
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870154
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5221
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84145
NR2F2	ENCODE Transcription Factor Targets	1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42751
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862841
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15679
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.52477
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900568
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1597
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
18410693-TableS8	GeneSigDB Published Gene Signatures	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3825
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0625
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17284
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1621
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84103
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_9_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
WM1799	DepMap CRISPR Gene Dependency	1.0	2.19159
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02994
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30126
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF-23-DD23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35661
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6359
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10551
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.08981
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73785
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04862
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385209
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.29341
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61024
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09263
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48871
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3678
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255641
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15436
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31782
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66914
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19634
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01427
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7254
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07832
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46154
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38398
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54761
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28672
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43745
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
cellular response to oxygen-containing compound	GO Biological Process Annotations 2023	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3316
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	2.26767
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29706
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21723
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447383
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4497_KO_Hnf4a/Hnf4g_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_vs_control-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03271
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28311
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911684
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.66156
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418367
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875371
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730988
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920912
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39613
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.45252
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24033
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966971
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_SMC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32943
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6745
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0674
Perturb_16416_Mut_Gli2_SRP154383	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23069
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41337
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10238
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.83684
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72431
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07495
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362486
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.84989
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87223
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2023	1.0	null
MDST8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.61191
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9513
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.004
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.719587
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5482
PMC8850648-Table11.xlsx-KS-DEGs_Vs_Liu_et_al_2019-Are_listed_the_239_DEGs_in_common_between_the_current_study_and_the_published_RNAseq_data_of_NRF1_overexpression_in_human_cells_Liu_et_al_2019_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08134
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.960178
Perturb_17042_KO_Phf6_SRP153916	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0128
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941833
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97146
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_12_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63365
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17431_KO_Tcf7_SRP096345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0074
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.652
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6169
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.60292
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84935
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.038916
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20748
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11486
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2386
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285107
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15182
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98854
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28435
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3506
Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37636
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11915_KO_Rankl_SRP190820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.36072
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46959
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830108
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.88316
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950615
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Thymus-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	0.762943
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blood serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2265
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8093
Ku70:Ku80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0105
Perturb_14613_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.45441
Prostate adenocarcinoma_PRAD_TCGA-HC-7230-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07047
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.83101
GSE131649_6_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49647
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LS180	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68187
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16879
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23208
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892675
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.05396
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
PMC11769988-Table1.xlsx-Table_S3-Table_S3_SCLC-related_genes_screened_by_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14336
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29623
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903879
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.08397
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02847
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3937
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911352
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5726
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10695
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.5388
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836675
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.434075
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.07911
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13581
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14204
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39294
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03258
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37084
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864125
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1377
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.33249
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830485
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.980469
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05495
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.396
protein stabilization	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10961
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.46096
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05445
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864806
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5764
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874345
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17975
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9097
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22919
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18747
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030679
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4316
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295251
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35851
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.372
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8039
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71609
DA-10-VU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206626
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05041
Fibrosis	CTD Gene-Disease Associations	1.0	1.38327
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02092
GTEX-Q2AH-1726-SM-3NB2B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899125
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.09456
A-Vietnam-1203-2004(H5N1)_2day-IDO1KO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.02209
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960836
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01238
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9667
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.427
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16971
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.39682
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846066
MEF-2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52166
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15749
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64795
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21048
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.759
CLPP_KO_GSE40207_396_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuronal ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
Perturb_8792_KD_LKB1_SRP045048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3158
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363194
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9023
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5861
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47133
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.621
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-22-GO73_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.489095
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02454
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2533
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.5684
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46533
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9526
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.33249
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33947
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955288
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05237
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7203476-Table_3.XLSX-Sheet1-GV_MI_overlap_227_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23926
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496766
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88985
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88248
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77537
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86293
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317206
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97363
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4B_BATF3_upreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.698502
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24349
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66747
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3528
U-251MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
DE-99-OT37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22634
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.33411
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2626
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukocyte disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.105
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93007
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15458
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5784
Lung adenocarcinoma_LUAD_TCGA-67-6216-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10563216-12917_2023_3758_MOESM1_ESM.xlsx-LPS_vs_NC-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6361-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2471
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.741
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01609
Perturb_1496_KO_Srp54c_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53426
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	2.43059
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.087
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08529
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.0198
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1793
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26443
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_2750_KO_STING1_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.114
Prostate adenocarcinoma_PRAD_TCGA-J4-A6M7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
Perturb_13855_KD_IGF2BP1_SRP284043	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.53699
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.830783
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.54498
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.14278
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30587
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1567
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6195
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12185
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.80572
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93454
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964434
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.944927
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H513	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.01799
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139239_3_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309632
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21356
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828983
COPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59555
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.4465
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.792
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41938
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219704
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.59909
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893412
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.067615
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOX_01_331	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.01084
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.34839
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.1983
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828222
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31656
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1324
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952281
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87475
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.71061
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71879
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.534
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	1.25809
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99091
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.62525
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.36429
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203548
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96233
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86492
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20264
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886783
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1213
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40259
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839404
OAW42	DepMap CRISPR Gene Dependency	1.0	2.59998
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854548
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05858
VCP-NSFL1C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.902
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43217
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321786
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921604
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0278
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21333
Brain Lower Grade Glioma_LGG_TCGA-E1-5322-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639563
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cortex	GeneRIF Biological Term Annotations	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17835
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58106
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237979
valproic acid_mus musculus_gpl6885_gse35291	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5878
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.095913
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03403
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38559
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200446_1_v_2_srsf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.5136
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565787
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-c_GATA2_R361_whole_sample_DEGs-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5265
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98507
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0226
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7346
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55336
MSTO211H	DepMap CRISPR Gene Dependency	1.0	3.07845
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5842026-mmc5.xlsx-HIC1_directTargets_48h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284267
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64924
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.40636
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2552
GSE75976_3_v_9_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.61406
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886556
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7325
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.784905
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10269
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91354
abnormality of immune serum protein physiology	GWASdb SNP-Phenotype Associations	1.0	0.825497
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25119
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_8409_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.07711
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27764
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87742
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97294
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17228
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.9619
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHUEM1	CCLE Cell Line Gene Expression Profiles	1.0	1.64763
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1671
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989624
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23053
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842249
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6573
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57227
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660694
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842387
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07528
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.00847
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09111
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825137
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO-800	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.50564
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01374
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.01267
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.81295
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.14259
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60465
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7588-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7772
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89226
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37128
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91414
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943901
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4488
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4254
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.31587
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.863974
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98131
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9004
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39515
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70935
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TAL1_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77299
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1942
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4724
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45165
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4273
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09244
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.713771
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20672
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06082
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9339
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56616
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.930589
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25777
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06004
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0293
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852301
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7121
RAJI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47508
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885462
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21919
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.25936
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8228
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49925
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7735
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	6.96236
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6315
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vasculature-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	2.36677
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858729
CRCGN014_HEPG2_3H:C14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01594
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64743
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844858
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_SOX2_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RDX	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_735_KD_PAF1_SRP048744	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57314
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853321
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_14013_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17757
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22933
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0142
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14945
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.242
Superior colliculus, motor related, intermediate gray layer, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32709
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09795
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2203
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5366
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26437
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33074
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.12082
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0086
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.02629
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10618
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41493
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1275
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70148
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896864
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06828
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76721
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22761
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU738	CCLE Cell Line Gene Expression Profiles	1.0	1.48259
Lung squamous cell carcinoma_LUSC_TCGA-70-6723-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49244
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.38756
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46938
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21026
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97121
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13533
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6982
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04741
JM1	CCLE Cell Line Gene Expression Profiles	1.0	1.76515
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15522
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26131
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0024
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37775
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1744
KP2	DepMap CRISPR Gene Dependency	1.0	3.75628
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4423
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0127
GSE146949_1_v_0_hemgn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN011_HEPG2_24H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23415
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
QF-05-OL72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212257
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	1.96219
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-0_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD3	ChEA Transcription Factor Targets	1.0	null
NCIH1650	DepMap CRISPR Gene Dependency	1.0	2.83535
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50424
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34594
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995819
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62906
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.1036
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10352
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38532
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial basal reticular formation of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28638
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03699
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33006
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86513
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0164
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.126563
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7625_KD_ICE1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.98409
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.096
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66347
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.265263
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72133
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30414
Perturb_5559_KO_Wdr26_SRP212064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.5776
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59212
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57559
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05003
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965564
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05675
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939933
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87998
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.87557
SIN3B	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hs-578-T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.39107
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4598
Perturb_5243_KO_E2A_SRP272063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.3449
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14806
Blood microparticle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9888
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03458
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0809
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08889
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2335
mRNA_ZFX_17448993	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48601
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.41386
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32778
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317603
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5737
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4824
CDK7_knockdown_124_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65038
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06688
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92611
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866182
LS180_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.09873
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208302
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Triglyceride levels in HIV infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
Leukopenia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.105
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16625
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967969
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.890751
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.8806
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.6636
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25454
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862087
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.487419
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.00279
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11316
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18583
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0825
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75735
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12715
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-7-5p	MiRTarBase microRNA Targets	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1_01_322	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.83928
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_5_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
irf8_00000000_splenic_cd11bplusgrdash1_hdash2b_gen_background_lof_mouse_gpl6887_gse39228	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.143775
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872844
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07222
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29753
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Plasma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4682
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17606
PMC6739105-aau4139_Table_S5.xlsx-CMC-TCF4_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01176
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44654
GSE223008_6_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MHCC97-H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6371
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1593
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0009
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02097
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36234
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6132
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epidermal lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3339
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.04085
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3331
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00986
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29674
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854807
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.5235
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2572
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC9399107-41467_2022_32627_MOESM6_ESM.xlsx-20_T-cell_subsets-gene_name_CD8_C1_LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.824241
Perturb_6341_KO_LONP1_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NatB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2492
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44183
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.0791
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66103
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13651
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3273
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3343
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN18	DepMap CRISPR Gene Dependency	1.0	3.55511
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21928
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224926
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24937
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848838
GA-88-CF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335205
GABPA	ENCODE Transcription Factor Targets	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03764
SNU1	CCLE Cell Line Gene Expression Profiles	1.0	1.68502
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.19662
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9961
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5905
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861872
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.19542
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1955
Perturb_5010_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02917
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12026
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MUTZ5	CCLE Cell Line Gene Expression Profiles	1.0	2.52848
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926213
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1776
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09857
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56416
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05041
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.36905
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04874
MCAS	DepMap CRISPR Gene Dependency	1.0	2.21287
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13106
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
interleukin-5 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14384
PMC5308218__F4	PFOCR Pathway Figure Associations 2023	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906971
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4104
Bursa of Fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.90377
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9085_KO_YAP_SRP297717	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04112
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82231
BA-97-CI76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241333
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7684
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.47418
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30221
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46678
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9738
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68095
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38011
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97305
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9411
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24384
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38011
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15495
sclc21h	HPA Cell Line Gene Expression Profiles	-1.0	-1.11669
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.478308
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66247
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1466
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18481
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31159
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16364_KO_Cryab/Hspb2_SRP055864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.42721
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893412
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10754
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65537
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37251
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1025
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0626
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1949
NCI-H1048	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.67637
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7693
NCIH460	CCLE Cell Line Gene CNV Profiles	1.0	1.61244
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926195
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21576
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932313
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44961
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20966
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7731
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98678
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8957
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249644
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925135
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CNOT3	ChEA Transcription Factor Targets	1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41337
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34293
PBX3	ENCODE Transcription Factor Targets	1.0	null
KYSE180	DepMap CRISPR Gene Dependency	1.0	2.1871
MAZ	ENCODE Transcription Factor Targets	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00368
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0717
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.44157
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15048
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86431
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4981
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90691
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6497
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463387
binding	GO Molecular Function Annotations 2015	1.0	null
GSE111501,GSE111502_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.79189
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2603
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDGFRB_knockdown_114_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.59021
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
AA-69-TD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382829
TCF4	ChEA Transcription Factor Targets	1.0	null
BRCA1_02_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6263
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13692
intermediate stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79291
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29304
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06662
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28675
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1423
women	GeneRIF Biological Term Annotations	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAPCLONEFGC_PROSTATE	CCLE Cell Line Proteomics	1.0	2.53195
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61139
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949514
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.8583
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7908
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26307
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894475
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.73255
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26319
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	3.78987
KYSE-50	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.42265
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09383
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43342
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05269
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94371
Perturb_5583_KO_NFKBIA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.61073
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.76522
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.634242
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01549
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0127
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.45035
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4593
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49148
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	3.24418
Perturb_3534_KD_KIF2C_SRP339333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81926
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06285
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.77319
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6497
SOX11	ChEA Transcription Factor Targets	1.0	null
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.462458
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06431
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14636
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05996
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827534
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39126
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL3-OVERLAP_GENES_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2896
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51894
GSE124410_2_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3284
OSC-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27393
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82537
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922242
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.946441
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3932
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.962376
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.10994
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AE-06-FY47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26552
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2563
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00888
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988224
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	1.02003
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUDHL10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75125
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.57425
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25161
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.6691
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.84311
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15723
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05121
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910724
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37614
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9079
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0186
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13963
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17466_KO_Prm7_SRP067359	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.62261
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846066
response to calcium ion	GO Biological Process Annotations 2025	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47495
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48162
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995839
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54343
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03297
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0257
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900001
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05018
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830899
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31754
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190761_0_v_1_samd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	1.81201
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33203
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.16533
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3049
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74383
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960892
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958408
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13515_KO_AK2_SRP326644	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.02944
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903459
GSE146253_0_v_2_stat4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563905
TRIM28	ENCODE Transcription Factor Targets	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.43376
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FB-32-PY27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406115
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36195
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4611
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980548
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13509
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.90925
Perturb_9806_KO_EBF4_SRP381947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.85497
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23458
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8931_KD_HNRNPL_SRP295547	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06415
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11368
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.84199
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26432
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7402
BE-66-UB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230747
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20592
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1469
RFX5	ENCODE Transcription Factor Targets	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86894
PMC12804025-mmc2.xlsx-LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCoV-EMC2012_7Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15414
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51102
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10172
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58168
COPS5	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_3179_KO_ubKDM1A_SRP348808	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.61026
PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE116492,GSE116495_3_v_1_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02885
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249394
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.6734
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37389
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02719
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984364
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.80018
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSRFC4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913629
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289351
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.58269
Collagen type VI trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.38
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8237
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.520657
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
chr3_194364494_G_A_b38	GTEx eQTL 2025	1.0	2.71111
ESS-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28491
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO-668	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.12713
Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31584
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.831
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858248
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35357
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.37191
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5972
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889948
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07639
POR_KO_GDS1678_761_mouse_ILEUM	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740102
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMPK gamma-3_KO_GDS1938_163_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114992,GSE114993_4_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.71294
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01864
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23919
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6545
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246057
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.06044
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
GSE87615_0_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_435_OE_miR1343_SRP066865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22006
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74583
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1311_KO_Cntnap4_SRP386887	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.32299
OV90_OVARY	CCLE Cell Line Proteomics	1.0	4.56632
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.24119
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33926
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05106
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30472
CHP212	DepMap CRISPR Gene Dependency	1.0	2.06502
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859337
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62533
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62693
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923804
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.5447
FOSL1	ENCODE Transcription Factor Targets	1.0	null
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922405
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9394
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4332150-msb0011-0775-sd13.xlsx-JUN-Prey_Gene_Symbol_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829332
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.37864
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41744
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04819
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular response to metal ion	GO Biological Process Annotations 2025	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977064
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59152
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888329
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CRCGN009_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08822
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5169
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06682
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44301
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07486
Perturb_1180_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9223
hsa-miR-638	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858394
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0229