association	dataset	threshold value	standardized value
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167752
Photosystem I reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
ETC-206_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0121667
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0224036
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199022
K562_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140349
K562_Curcumin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187701
K562_Trametinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0330795
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173612
Semimembranosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
PMC6010319-aap7309_tableS1.xlsx-TET1_low_tumors-Gene_Symbol_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
Edoxaban (tosylate monohydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0293528
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Fluticasone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
LJI308_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0224327
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143799
Zonisamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50344
K562_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0275826
K562_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0376733
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Hesperadin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.275184
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
abnormal basement membrane morphology	MGI Mouse Phenotype Associations 2023	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01231
K562_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241699
K562_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158104
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71209
K562_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0209558
increased neutrophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
Congenital muscular dystrophy-dystroglycanopathy A7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.765
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27838
K562_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149683
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital muscular dystrophy-dystroglycanopathy type A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.543
K562_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0274177
K562_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0283809
Congenital muscular dystrophy-dystroglycanopathy type A10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0319785
Thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
K562_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033103
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234448
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0259296
Congenital nervous system abnormality	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
K562_Busulfan_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223716
K562_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0543756
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.22735
Congenital muscular dystrophy-dystroglycanopathy type A3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39036
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4622
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dxr protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.525
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.38708
Pyrene	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.54592
Muscular disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0366371
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148969
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
K562_Tazemetostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179821
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Division septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant limb-girdle muscular dystrophy type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.508
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0303419
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
olaparib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223423
K562_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214117
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant limb-girdle muscular dystrophy type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03075
K562_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0295084
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-30970003-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
K562_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0570575
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7339813-Supplementary_Data2.docx-47-PRDM1_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.461
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
K562_Dacinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0303927
K562_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023076
MIS12/MIND type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268675
protein O-linked mannosylation	GO Biological Process Annotations 2023	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8189
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0255845
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25256
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00188
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1549
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
K562_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170247
K562_RG108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226039
Thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
Ro-3306	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.86
K562_TMP195_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170815
K562_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145375
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Muscular dystrophy-dystroglycanopathy type B5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.337
Rigid spine muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
K562_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0480413
K562_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186777
K562_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0548308
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8733
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18893
limb-girdle muscular dystrophy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
K562_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198097
K562_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.038565
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
radial glial endfoot detachment	MGI Mouse Phenotype Associations 2023	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.729434
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_JNJ-26854165_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178766
Myofibrillar myopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
Capmatinib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0402494
GSE146247_0_v_1_sirt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
Brazilian hemorrhagic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
K562_GSK J1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197161
GSE178255_3_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0277944
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
K562_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0349301
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
PMC6565995__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16099
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180276
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0385097
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60408
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0248
K562_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0447557
Sartorius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Crizotinib (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0178104
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150972
PMC4117606__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mebendazole_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0151117
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
K562_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0362747
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
GSE183316,GSE183317_1_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Emery-Dreifuss muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Histrionic personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
Cervical dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
K562_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0343914
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
protein mannosylation	GO Biological Process Annotations 2023	1.0	null
K562_ENMD-2076_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176388
K562_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0685545
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21194
Belumosudil (mesylate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257167
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02803
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4307
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2002
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1057
Specific phobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
K562_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0297553
GSE155305_3_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0336699
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0343857
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14252
CAAX-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0702
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Acromelic frontonasal dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
PMC4271336-13041_2014_88_MOESM6_ESM.xlsx-Genes_in_GENE_CARD_MR_or_ID-Gene_Cards_MR_and_ID_genes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
K562_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163852
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BMS-911543	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163932
Quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
TEDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20743
(R)-Verapamil (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0407236
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9177
K562_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0456786
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
Chromoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
K562_Tacedinaline_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0290274
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39373
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adagrasib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0211702
K562_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0287768
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08992
Autosomal recessive limb-girdle muscular dystrophy type 2X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
K562_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0296952
K562_JQ1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0432882
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3073
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amsacrine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0173957
K562_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0245971
ectopic neuron	MGI Mouse Phenotype Associations 2023	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8802
GSK1059615_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0210097
K562_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237093
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
K562_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023581
Orlistat_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152419
Muscular dystrophy-dystroglycanopathy type B3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
K562_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0410676
Migalastat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200088
K562_Meprednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0311178
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70279
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Clotrimazole_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0290446
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0381958
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43077
K562_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139856
K562_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0215423
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
GNAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24112
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28871
Serum tamsulosin hydrochloride concentration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GSE183316,GSE183317_4_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vilanterol_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0262254
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167697
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1957
GSE158595_0_v_1_e4f1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
Lenalidomide (hemihydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0384872
K562_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270596
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
decreased lymphocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
K562_IOX2_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166479
K562_Givinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0243567
K562_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217395
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
Flexor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24175
Extensor digitorum brevis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Panic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9363
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38304
Adductor longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
Myopathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
chr7_16419517_T_TTA_b38	GTEx eQTL 2025	1.0	1.04828
K562_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.027384
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9794
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ribociclib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0203711
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11814
Gemcitabine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0244122
MK-8353_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0260049
Babesiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158876
K562_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.08141
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fenofibrate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0253185
K562_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0248001
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1772
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5559
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscular dystrophy-dystroglycanopathy type B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.692
K562_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196347
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27809
K562_Baricitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0468997
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03518
Autosomal recessive limb-girdle muscular dystrophy type 2S	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.332
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epirubicin (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.032182
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0421374
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195564
K562_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168939
IMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41516
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143498
K562_Cediranib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158751
Agoraphobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0313716
GSE232944_1_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22951
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.65809
K562_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206978
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68347
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213726
K562_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.028068
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2256
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02938
early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
Autosomal recessive limb-girdle muscular dystrophy type 2I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.787
Lucanthone_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0288953
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Muscular dystrophy-dystroglycanopathy type B4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.366
K562_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.035941
Oil secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Anacetrapib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07759
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0274235
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
K562_Filgotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0331972
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
PLD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34174
GSE123887,GSE123888_2_v_1_hpgd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0522678
K562_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0496702
nucleotidyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
GSK189254A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
CHEMBL2041153	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
Macula lutea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
PMC11472072-mmc2.pdf-2-CYP1B1_PAX6_ELP4_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.026286
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1865
Bergenin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0509616
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6171
K562_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0278516
K562_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145804
Peltate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6093
Autosomal recessive limb-girdle muscular dystrophy type 2P	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Persistent hyperplastic primary vitreous	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
K562_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202126
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213625
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025649
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0661
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31683
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ritonavir_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0136675
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6781
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0298983
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital Muscular Dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
K562_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.03254
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
K562_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0302352
K562_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0282057
PF429242	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
Ataluren_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0116912
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21542
K562_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174039
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9037
K562_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.035915
PMC5595898__F6	PFOCR Pathway Figure Associations 2023	1.0	null
K562_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0393601
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1417
Centronuclear myopathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11605
Distal myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171617
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
Impulsivity (non-planning)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_3_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ornidazole_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0171202
K562_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0249573
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3407
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06877
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.642236
K562_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0414784
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
increased mean platelet volume	IMPC Knockout Mouse Phenotypes	1.0	null
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9902
Aliskiren_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.038647
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249313
abnormal nervous system tract morphology	MGI Mouse Phenotype Associations 2023	1.0	null
K562_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0309395
Fostamatinib (disodium hexahydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0159285
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.279
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
Pioglitazone_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0209916
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34713
ULK-101_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0240265
K562_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.033398
K562_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.028028
K562_GSK-LSD1 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0266017
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Benzbromarone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
Vernakalant	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
K562_Ki8751_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170596
K562_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0268052
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162319
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9449
PMC4973221__F3	PFOCR Pathway Figure Associations 2023	1.0	null
K562_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0391493
Diammonium Glycyrrhizinate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0236849
K562_UNC0379_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012849
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Nemaline myopathy 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
K562_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025311
Miyoshi muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Narcissistic personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158396
Finasteride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Olopatadine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0390812
K562_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234312
Olanzapine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0252961
Acetazolamide_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195178
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83528
K562_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0338774
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0265894
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-156-MEOX2_MEOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.9684
K562_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0537662
Belinostat_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0188867
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4101
K562_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136525
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8015
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.71006
K562_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0456621
K562_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0540119
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
K562_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.028483
K562_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0460575
Cavum septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
K562_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0236512
K562_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223258
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
K562_TGX-221_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213718
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-605-ENSG00000106511_MEOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0408696
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06048
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5984
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71601
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19416
K562_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0276469
K562_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254522
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1057
Primary congenital glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46527
K562_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0309661
K562_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0267685
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4879
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67103
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
K562_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175196
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
Bethlem myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
K562_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246806
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02348
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59666
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FLO-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
K562_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189877
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anastrozole_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.020676
Aspirin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0155817
K562_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.040107
ZNF496	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09452
K562_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015734
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11298
PMC6078071__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Congenital muscular dystrophy 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5301
Autosomal recessive limb-girdle muscular dystrophy type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2455
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0285607
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Gastroschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Malotilate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0375758
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
K562_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181675
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
K562_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222311
Ibrutinib1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
Temuterkib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0126106
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27466
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49289
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178467
K562_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152937
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198474
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.54443
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0342803
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0244
K562_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0364951
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8345
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
K562_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151338
K562_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0323446
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10397
Benproperine (phosphate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0267583
K562_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018888
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59609
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34927
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0327873
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
Aprepitant_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.015578
K562_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190204
Autosomal recessive limb-girdle muscular dystrophy type 2W	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
nucleotidyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5856
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2991
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Distal myopathy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
K562_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0347615
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.423
Triclosan_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0368127
K562_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014887
Autosomal recessive limb-girdle muscular dystrophy type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
K562_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0611625
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13019
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.176
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3009
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189422
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
Exoerythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.072
K562_Pirarubicin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0244636
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3441
K562_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147804
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98172
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35025
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
K562_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0241662
K562_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218567
K562_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0458381
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24817
K562_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0619675
Scapula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10823
LinE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.075
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Phobic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0331688
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Allopurinol_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0281545
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ramelteon_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0273921
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0435167
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AZD2858_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0254304
Bimiralisib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223469
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
K562_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.033494
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sivelestat (sodium tetrahydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0124015
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0301734
K562_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214166
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02268
Gallic acid_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0346758
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
protein mannosylation	GO Biological Process Annotations 2025	1.0	null
K562_Alvespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0436174
GSE129648,GSE129650_2_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4926
Muscular dystrophy-dystroglycanopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.758
Mannose type O-glycan biosynthesis	KEGG Pathways 2026	1.0	null
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.145
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pentose and glucuronate interconversions	KEGG Pathways 2026	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.041912
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5038
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dihydroartemisinin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0250447
abnormal spinal cord dorsal column morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC3686787__F2	PFOCR Pathway Figure Associations 2023	1.0	null
K562_Selisistat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019536
Carey-Fineman-Ziter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
cytidylyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
K562_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236882
decreased lymphocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2373
Autosomal recessive limb-girdle muscular dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
K562_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191639
K562_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0253969
K562_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146296
Bothnia retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
PMC5727528__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE120781,GSE174528_4_v_1_ctcf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal spinal cord ventral commissure morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.425
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4827
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Muscular dystrophy-dystroglycanopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
Walker-Warburg syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Impulsivity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
K562_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188842
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198318
K562_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195266
abnormal axon fasciculation	MGI Mouse Phenotype Associations 2023	1.0	null
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
PMC7825356-8844261.f3.docx-33-ZNF695_ZNF695	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22555
K562_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0963912
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.0
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4573
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7895
K562_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0513529
Isotretinoin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
increased mean platelet volume	MGI Mouse Phenotype Associations 2023	1.0	null
K562_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160949
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155154
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69806
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Odanacatib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0264835
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
MCF7_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0083754
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021274
K562_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0334805
K562_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0360493
K562_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0319281
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.028513
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0304289
K562_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018208
K562_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181017
Autosomal dominant limb-girdle muscular dystrophy type 1H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2827
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16829
Slit-Robo signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6685
K562_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0299706
K562_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0393162
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Nuclear MIS12/MIND complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
Cytarabine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0263547
Methotrexate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0128526
K562_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0578524
K562_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254759
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7312
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2N	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.442
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06045
protein O-linked glycosylation	GO Biological Process Annotations 2025	1.0	null
HI-TOPK-032_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163056
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19114
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0261828
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08845
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.52
GSE164364_2_v_1_zymosan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5778
K562_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0378498
K562_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284338
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.41909
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1218
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
K562_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210263
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56834
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0269618
K562_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0288256
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Rix1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
Congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.991
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0413285
Rectus femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
K562_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0323087
K562_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226287
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193999,GSE194000_1_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.698
Thymopentin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0194501
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carotid plaque maximum area	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Muscular dystrophy-dystroglycanopathy type B6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.551
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0356211
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dolichyl-phosphate-mannose-protein mannosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.952
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
K562_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020709
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7404
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.398
K562_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0384831
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2026
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
Congenital muscular dystrophy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
Almonertinib (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0213921
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Andarine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188624
K562_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0722767
K562_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227544
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
PMC9365857-41598_2022_17887_MOESM1_ESM.docx-1-IKZF4_IKZF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22578
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Methylprednisolone succinate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00953468
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0205971
Autosomal dominant limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178816
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
K562_Avagacestat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0328883
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
K562_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128547
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00343
Quinidine (15% dihydroquinidine)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0252229
MCF7_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119828
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03764
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168894
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0348276
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0443693
Mozavaptan_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.026678
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Etioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
K562_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218082
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.99349
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0017
K562_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134614
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54029
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0351418
K562_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0277458
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0411927
PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195305
K562_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0603257
Cerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
K562_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154904
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Auranofin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0247118
K562_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250222
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary interstitial emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
K562_ZM 447439_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0317575
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0320777
Myofibrillar myopathy 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09912
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sildenafil_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0157736
K562_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216295
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7839
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0335
abnormal axon guidance	MGI Mouse Phenotype Associations 2023	1.0	null
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0561675
Bronchopulmonary dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
respiratory failure	MGI Mouse Phenotype Associations 2023	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
K562_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0313581
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3756
K562_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241048
Autosomal recessive limb-girdle muscular dystrophy type 2M	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
K562_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0371478
Vemurafenib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00859821
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0265055
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.386
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24272
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
LY2090314_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0282539
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166462
K562_ABT-737_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0425443
protein O-linked glycosylation	GO Biological Process Annotations 2023	1.0	null
K562_Bisindolylmaleimide IX_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018525
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48149
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Sulcotrione	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
PMC7204122-4623107.f1.docx-7-GZF1_GZF1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
K562_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0341353
K562_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0473098
K562_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0206758
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
K562_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230319
Waist-to-hip ratio adjusted for BMI x sex interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
Hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6078963-41467_2018_5311_MOESM9_ESM.xlsx-PPARD_CHIP_vs_RNA_CD34-PPARD_macrophages_Vs_RNA_CD34_OE_DEGs_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37875
K562_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172128
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
K562_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159117
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
K562_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0356792
K562_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0215249
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.513
K562_Thalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161197
Schwann cell microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
K562_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0566946
K562_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0471257
Pemetrexed_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0219256
K562_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0241279
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56495
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60391
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
K562_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0275052
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant limb-girdle muscular dystrophy type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13371
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
laminin-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
PMC7296177__F1	PFOCR Pathway Figure Associations 2023	1.0	null
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88573
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Aminodeoxychorismate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
K562_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023385
BI-3406_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0141819
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07247
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28169
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
K562_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202095
cas1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
K562_Barasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.047083
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131269
Bestatin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0276498
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5723
K562_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211713
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15093
K562_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0506705
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APTO-253_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.018699
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Budesonide_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0264049
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271578
K562_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0437081
K562_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166158
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5692555-pnas.1708341114.sd04.xlsx-3TFs_no_GATA2-gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
K562_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272644
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
Medroxyprogesterone acetate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0303741
K562_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0371587
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
bp86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0474439
Palmatine (chloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.010469
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.39893
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.911755
K562_Alendronate sodium trihydrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212456
K562_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0464764
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital muscular dystrophy due to integrin alpha-7 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
K562_Prednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0355177
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159681
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29702
Fleck corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
K562_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270685
K562_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0417018
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.88996
Mean area of carotid plaque	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
K562_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.033328
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62554
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32797
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2O	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.314
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185227
TR-14035	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
ATP-dependent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
K562_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0332107
ZNF324	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93555
K562_Obatoclax Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161152
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Muscle tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.832485
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
K562_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.034658
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0305519
Autosomal recessive limb-girdle muscular dystrophy type 2J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.961
GSE183316,GSE183317_3_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Methylnaltrexone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
K562_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0240929
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36765
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13321
Torasemide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
Nuchal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
K562_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0463463
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2552
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100886,GSE100893_1_v_3_parp14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CP21R7_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0112799
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
K562_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172771
Muscular dystrophy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0564408
K562_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0441307
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0265745
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
f2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
Icotinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.65
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2694
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
BD 1008	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
Berberine (chloride hydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.037
PMC7301438__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70568
K562_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023014
Myofibrillar myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6221654__F5	PFOCR Pathway Figure Associations 2023	1.0	null
K562_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0325839
K562_Tozasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198646
K562_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0397862
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4507
Heel bone mineral density	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
K562_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0244792
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.377
Autosomal recessive limb-girdle muscular dystrophy type 2Q	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
K562_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172185
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58142
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Regorafenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190726
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42001
Autosomal recessive limb-girdle muscular dystrophy type 2H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14485
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0402348
Autosomal recessive limb-girdle muscular dystrophy type 2Y	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
K562_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0346281
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145946
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18029
K562_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0346236
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
K562_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237252
K562_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012601
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0329507
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3527
K562_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159102
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9305
NCI-H520 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha7-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
K562_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0243994
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0338266
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1278
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23748
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179722
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8653
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_7_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5584320__F8	PFOCR Pathway Figure Associations 2023	1.0	null
Brachydactyly type C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
K562_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0352846
K562_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0351413
K562_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0341956
Autosomal recessive limb-girdle muscular dystrophy type 2U	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.858
K562_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0421442
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.633
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.136
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09134
K562_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239517
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179094
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1227
A549_FLLL32_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137813
Abiraterone1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
Azithromycin (hydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.02703
Hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
K562_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0366911
K562_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0406167
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44232
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	1.95783
K562_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0329719
K562_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172893
Bimatoprost_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.021984
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
Benzo[a]pyrene	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
cytidylyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lissencephaly	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Docetaxel (Trihydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.018133
K562_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0294615
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Secretory trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
K562_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0308847
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.23844
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18842
Congenital muscular dystrophy-dystroglycanopathy type A11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
Mitoxantrone (dihydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0165762
GW 441756	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Becker muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.07
K562_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204547
K562_Crizotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211756
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4845
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Hesperadin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0888993
chr7_16400026_A_G_b38	GTEx eQTL 2025	1.0	2.01854
Thymol_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0188743
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
K562_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141059
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5514
Bestatin (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0231893
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09418
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11805
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8125
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ligustrazine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0233698
K562_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0468043
Congenital myopathy 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6512
Seedpod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
Talazoparib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0312736
K562_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188598
K562_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0260728
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Pramipexole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.72
K562_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127156
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27033
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
K562_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0270473
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Loperamide (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0220602
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04544
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05982
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5923
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein O-linked mannosylation	GO Biological Process Annotations 2025	1.0	null
Tucatinib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0256814
increased neutrophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
Nemaline myopathy 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Mocetinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0283938
Org25543	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27274
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Muscular dystrophy-dystroglycanopathy type C8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
K562_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0243425
K562_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158646
Walker-Warburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.15
Miyoshi muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40914
D-ribitol-5-phosphate cytidylyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mdamb134vi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
Polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
K562_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223294
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69478
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0206089
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2807
Gallic acid (hydrate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0300963
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.06012
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3428
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAK-901_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0277492
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4887
GSE226408_2_v_3_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
ZNF268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09872
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.00569
D-ribitol-5-phosphate cytidylyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tomivosertib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0120655
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
K562_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135514
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193093
K562_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0462927
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34973
Congenital merosin-deficient muscular dystrophy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
K562_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0485843
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal dominant distal hereditary motor neuronopathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1563
K562_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016202
K562_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0384026
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2196
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03469
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.40294
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.883
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.197
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
K562_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0380754
K562_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250855
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53786
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.221
K562_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0420074
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48346
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0435
K562_Anacardic Acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0360969
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14299
K562_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.024324
Autosomal recessive limb-girdle muscular dystrophy type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
Autosomal recessive limb-girdle muscular dystrophy type 2E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
GSE152432_6_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1997
PMC11461876-42003_2024_6975_MOESM5_ESM.xlsx-Supplementary_Data_3-Supplementary_Data_3_Differentially_Expressed_Genes_HSE_THP1_UV_Vs_HSE_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175555
K562_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0437841
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4524
K562_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015279
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2771
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.308
K562_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0367246
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
Rifaximin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0237007
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23381
K562_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0372021
Laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.65
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0265806
K562_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230182
Congenital myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Bisoprolol (hemifumarate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0191124
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.883
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21627
K562_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0370525
Plant secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
K562_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0312002
Distal myopathy with anterior tibial onset	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06839
Flutamide_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0180597
K562_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216202
Adenosine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0392133
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.363
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-213-IRF8_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187507
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1807
PMC4835424__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34664
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Bisindolylmaleimide IX_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158716
Social phobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
Autosomal recessive limb-girdle muscular dystrophy type 2F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2974
LB-100_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0316198
K562_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204123
K562_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0508267
GSE133213_9_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149943_1_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
Fukuyama congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.414
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plant oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
K562_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145116
K562_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233551
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58185
Leucoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2743
K562_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181758
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06407
Vandetanib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0214106
K562_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0259473
EX229_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0294189
K562_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250736
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Laropiprant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHCA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4933
K562_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239907
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194039
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2593
K562_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0360487
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2L	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01964
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.284
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
L-Eflornithine (monohydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0239413
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null