association	dataset	threshold value	standardized value
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42377
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72943
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0577
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62808
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5712
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40986
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28376
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40176
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.043
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48148
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4437
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3746
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79061
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47055
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.711
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33414
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38034
CRCGN015_HEPG2_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37072
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63619
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5924
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99861
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18337
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99428
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5576
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41699
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3128
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7913
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5048
CAMKK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43613
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1929
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0587
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16955
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00989
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0916
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59268
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67919
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06847
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78087
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63376
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12525
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11111
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34367
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06779
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51799
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46882
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19103
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71568
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30243
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1484
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90643
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5583
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1112
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87466
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61561
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
KCTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93172
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17944
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52656
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0685
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50128
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6983
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08228
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8409
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3345
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28264
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2735
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2427
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3608
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61859
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C14orf119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40487
TBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35593
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54696
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43829
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84474
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4909
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53553
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45314
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95972
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4757
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41441
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60848
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65105
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3753
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03314
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35145
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7805
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04298
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5791
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6006
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0881
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21547
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23955
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84699
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.704
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91861
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33297
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23663
CRCGN008_HEPG2_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07061
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99589
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19387
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60899
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05651
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7548
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53772
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2343
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86846
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03212
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69253
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55024
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34487
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84828
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8723
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54022
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21655
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4509
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15661
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50049
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75319
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06638
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84426
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41678
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10512
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7857
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84817
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45418
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.191
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6155
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
BCCIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94803
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09467
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50496
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43683
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69543
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08505
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9447
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60401
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5343
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75209
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41659
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69655
ITGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25997
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40657
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0307
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7129
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91505
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5296
MOSMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9114
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94933
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76981
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.49159
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56929
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88854
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91101
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSPYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42604
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19571
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1604
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7268
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60309
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34565
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3551
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0245
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66221
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65377
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49244
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39444
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38448
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54921
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04392
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4968
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.426
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1748
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8926
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8473
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93341
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.58817
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3154
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84769
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06504
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5237
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29396
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47132
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4556
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05433
YJU2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65728
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6659
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97769
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89885
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4007
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76832
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87317
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3839
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14742
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6689
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47195
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16806
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21933
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89274
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1884
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62649
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18305
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87953
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56858
GSE239768,GSE239769_1_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38046
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96471
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8419
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44679
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08904
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37889
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9205
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70124
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3098
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85516
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68505
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61496
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61188
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2753
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36859
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.494
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79395
MSRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16029
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46612
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3473
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91683
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96245
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.3068
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73834
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45583
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1692
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28789
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52068
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11673
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78549
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44222
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01719
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70665
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67012
RNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93825
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5815
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55231
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89867
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9519
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4381
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21551
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3821
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0152
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91124
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57296
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06955
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53315
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39613
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92138
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03121
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17345
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29663
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30993
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11463
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32262
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.984
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2406
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31666
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82976
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60615
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24086
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2189
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05518
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42485
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35272
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00435
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07985
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62691
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2079
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04976
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74721
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.012
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25843
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8404
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14341
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3874
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45461
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.144
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2605
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF626	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14613
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02184
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26386
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73525
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33897
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93483
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2395
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02034
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4154
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52203
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02908
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31017
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24405
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04634
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84058
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95184
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51177
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84222
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7398
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94102
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
PRR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67217
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50325
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04101
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06446
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2905
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.91949
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22425
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.94619
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4818
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0808
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14094
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94105
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94728
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63081
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66782
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4643
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7047
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2231
H2AC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47255
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0491
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.876
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0979
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55374
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29027
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.125
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5854
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2003
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35854
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3761
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36953
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34217
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6838
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0133
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47474
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57143
SNX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51753
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06694
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24801
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18907
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08869
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24784
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4585
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9763
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8545
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80907
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62038
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20742
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25912
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13154
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04495
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62522
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96137
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68006
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7533
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81403
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61859
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67625
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27732
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4101
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7924
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39921
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22066
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55219
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74411
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64181
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24547
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0592
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6919
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.057
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59112
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5085
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07449
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1726
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96275
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3173
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2199
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65873
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43993
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7462
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4103
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25698
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32623
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96041
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7826
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58059
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54489
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41163
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52943
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1462
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62109
BCL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15988
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68608
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16492
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8885
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78857
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69929
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66691
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07408
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29869
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81351
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9765
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09014
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43191
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37323
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51413
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8147
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14481
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35978
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11247
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63707
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36919
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27375
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62171
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20512
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35865
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6635
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08335
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC11909984-12943_2025_2285_MOESM1_ESM.pdf-6-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8233
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89122
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03587
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8187
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65725
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8853
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74179
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32635
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4842
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29166
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6858
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95411
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35691
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3722
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15629
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72662
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73432
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3653
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4199
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47157
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73179
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80036
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1202
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18415
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3967
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13968
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39453
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09527
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.537
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75349
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7881
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0675
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66633
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9627
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5823
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27901
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85597
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79301
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40813
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89965
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44391
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3709
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13087
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64282
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99363
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86023
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24536
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90726
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
DTWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72602
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2088
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17141
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1005
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12052
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8963
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54809
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20229
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64367
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26921
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14639
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3925
CRCGN017_MCF10A.TP53.M_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24923
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41127
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08323
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6083
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65792
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28582
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99969
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94642
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67499
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82539
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28271
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.932
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65057
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0606
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8735
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26878
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4568
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38016
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41955
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15508
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9295
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63827
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49699
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9848
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15237
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1886
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40179
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42239
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40428
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98708
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48031
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20211
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26965
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.5
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.585
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92412
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4582
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01998
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30217
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6062
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57874
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79696
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25092
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7083
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40956
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4576
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40885
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27362