association	dataset	threshold value	standardized value
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-2.1001
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28277
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.69967
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.344292
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.39013
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855852
NCIN87	DepMap CRISPR Gene Dependency	1.0	7.51372
Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARH77	DepMap CRISPR Gene Dependency	1.0	2.01692
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.682294
rectum	HPA Tissue Protein Expression Profiles	1.0	0.799077
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.799077
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TE15	CCLE Cell Line Gene Expression Profiles	1.0	1.37261
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SP2/0-AG14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12825
OSC19	DepMap CRISPR Gene Dependency	1.0	15.1737
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4326
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46018
E2F4	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-80-5607-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1847
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58201
Anchored component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248504
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.534434
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06613
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.204327
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986963
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826261
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.65926
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.819
cytotoxic t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22797
cerebellum	HPA Tissue Protein Expression Profiles	1.0	0.799077
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7177
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-47-ZI16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283012
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972564
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2742-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS18	CCLE Cell Line Gene Expression Profiles	-1.0	-2.58708
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
hsa-miR-520g	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63861
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Ileus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4634
MXI1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A444-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.33792
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084914
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.99952
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.121264
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40625
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1371
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21407
A704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65893
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.799077
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918282
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9698
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.032485
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2507
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5305
autosomal recessive disease	GWASdb SNP-Disease Associations	1.0	0.668171
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esr1_21713035_mcf7_lof_human_gpl570_gds4061	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.861904
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055316
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5425
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	0.916444
gastrointestinal obstruction	GWASdb SNP-Phenotype Associations	1.0	1.56399
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36041
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
lateral ventricle	HPA Tissue Protein Expression Profiles	1.0	0.799077
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041042
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	2.40259
Oropharyngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58979
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	4.11402
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055048
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7183
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4711-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SNU81	DepMap CRISPR Gene Dependency	1.0	13.2851
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.799077
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55689
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3208
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pleomorphic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9655
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Azoospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.176
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17321
non-Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05097
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-57-CF49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.532237
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9349
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418744
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849481
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056796
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.832893
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07264
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.0399
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5502
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1767
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.256654
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223784
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3565
EJM	CCLE Cell Line Gene Expression Profiles	1.0	1.61299
REST	ENCODE Transcription Factor Targets	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0568
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.52534
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24467
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18218
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
MORCPR	CCLE Cell Line Gene Expression Profiles	1.0	1.51815
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19208
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE280	DepMap CRISPR Gene Dependency	1.0	3.49652
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8902
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8821
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Tonne-Kalscheuer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68904
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039941
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6805
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11097
autosomal genetic disease	GWASdb SNP-Disease Associations	1.0	0.438375
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50086
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1179
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
oe19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
SNUC2A	CCLE Cell Line Gene Expression Profiles	1.0	2.04113
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE145639_7_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9975
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054772
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	2.88135
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal Metaplasia	DisGeNET Gene-Phenotype Associations	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.733
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0534
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72937
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9249
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508635
membrane part	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2554
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
Integral component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.841
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.506
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.8731
KATOIII	CCLE Cell Line Gene Expression Profiles	1.0	1.44365
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047368
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1998
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.479611
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.59371
GSE193993_0_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3792-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33485
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1501
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07107
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.06373
BJHTERT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53628
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.195
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942983
NCIH1563	CCLE Cell Line Gene Expression Profiles	1.0	1.71664
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
BB-51-DP49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226109
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5629-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072068
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5448
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201588
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Extrinsic component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02577
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986963
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Intrinsic component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.323
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
genetic disease	GWASdb SNP-Disease Associations	1.0	0.39188
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01735
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BT549	CCLE Cell Line Gene CNV Profiles	1.0	1.50534
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
functional abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.359208
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.799077
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6678
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9373
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0271
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.34669
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
meconium ileus	GWASdb SNP-Phenotype Associations	1.0	1.56399
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2172	CCLE Cell Line Gene Expression Profiles	1.0	1.96493
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8
EZH2	ENCODE Transcription Factor Targets	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05097
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.7735
U-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309204
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7467
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.79598
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06613
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054963
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061637
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8146
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.7947
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88139
Triple-Negative Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7978
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089042
GSE202434,GSE202438_15_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05801
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25961
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0392
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0849
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17612
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0593
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287804
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SCH	DepMap CRISPR Gene Dependency	1.0	6.1753
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3249
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6685
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80938
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4476
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46412
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
External side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.728
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
PIK3CA_mutant_27_GDS4053	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72548
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986963
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82466
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.613
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.829635
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.2118
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.139
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75448
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01858
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054394
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5908
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3653
Infection Caused By Helicobacter Pylori	DisGeNET Gene-Disease Associations	1.0	null
TMK1	DepMap CRISPR Gene Dependency	1.0	3.47323
Intestinal obstruction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
SW-1116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
KCIMOH1	CCLE Cell Line Gene Expression Profiles	1.0	1.46562
Synovium cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Microinvasive gastric cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.165
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.799077
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053764
NCIH650	CCLE Cell Line Gene Expression Profiles	1.0	1.68143
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.25669
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993733
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
2313287	CCLE Cell Line Gene Expression Profiles	1.0	1.88163
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978947
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06731
RPMI7951	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3463
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH1915	CCLE Cell Line Gene Expression Profiles	1.0	1.57396
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8158
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral blood lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360409
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.546256
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13487
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12825
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
Vaginal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	2.09958
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_UCEC_NOT_CESC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835908
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88179
placenta	HPA Tissue Protein Expression Profiles	1.0	0.799077
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-1622-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.836017
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
lung adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128111
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.07115
HOS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51911
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69067
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08132
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7524
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A59Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7769_KD_Y14_DRP003223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.83517
Gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42045
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
hippocampus	HPA Tissue Protein Expression Profiles	1.0	0.799077
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52596
NCIH1869	DepMap CRISPR Gene Dependency	1.0	4.71318
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal dysmotility	GWASdb SNP-Phenotype Associations	1.0	1.56399
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.58475
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266401
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MCF-10A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5836
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35003
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.82
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.47253
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062133
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0233
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057567
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518859
Perturb_7768_KD_EXOC5_DRP001280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33503
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	5.75848
Perturb_15566_KD_YAP1_SRP333272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41252
CORL47	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61139
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33359
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0057
Lung squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07469
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37726
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Anterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8492
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8848
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.617393
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.686368
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1708
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DNA repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918282
monogenic disease	GWASdb SNP-Disease Associations	1.0	0.414454
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6009
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8999
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42317
gamma-delta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.522659
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3567
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.533
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2119
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077164
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GABPA	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03376
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.926756
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67364
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253908
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRPK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Car cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52153
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mechanical ileus	GWASdb SNP-Phenotype Associations	1.0	1.56399
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60168
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71773
cell part	GO Cellular Component Annotations 2015	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8707
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062641
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48457
HCC1588	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85915
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Pyloric region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3125
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861081
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58902
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6686
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMC3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L33	CCLE Cell Line Gene Expression Profiles	1.0	2.15062
membrane	GO Cellular Component Annotations 2015	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.64968
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.493
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-9 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42962
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	1.54073
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	1.44863
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
ELK4	ENCODE Transcription Factor Targets	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4367
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3182
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3561
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254649_2_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Wilson-Turner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07595
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE175787_8_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4662-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7423
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9203
SRPK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.74914
Kita-kyushu lung cancer antigen 1	InterPro Predicted Protein Domain Annotations	1.0	null
Oligospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
disease	GWASdb SNP-Disease Associations	1.0	0.031161
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.293334
SNU308	CCLE Cell Line Gene CNV Profiles	1.0	1.41783
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ileus	GWASdb SNP-Phenotype Associations	1.0	1.56399
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860527
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238671
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.638
MAX	ENCODE Transcription Factor Targets	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07917
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.782725
CDK13	Kinase Library Serine Threonine Kinome Atlas	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76026
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HL-7533-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232047
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68243
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18438415-SuppData	GeneSigDB Published Gene Signatures	1.0	null
Infertility, Male	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9256
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49733
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	2.17478
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060862
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327225
Atrophic gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5047
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4868
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.453355
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.55683
Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7567-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202871
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
PF-39-DY68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289742
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826261
Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08771
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6019
Perturb_2604_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.91718
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826261
IM95	DepMap CRISPR Gene Dependency	1.0	2.09089
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971836
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
BEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86469
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.799077
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61726
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88139
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381826
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212711
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-BR-3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04409
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7601
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH1869	CCLE Cell Line Gene Expression Profiles	1.0	2.2381
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82098
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.46361
Cvt vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6142
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6373
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6902
severe combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487407
NCIH1355	CCLE Cell Line Gene Expression Profiles	1.0	2.89594
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09146
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53939
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6831
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3453
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.55771
SW1088	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12809
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045718
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.38581
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.135809
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716241
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC78	CCLE Cell Line Gene CNV Profiles	1.0	1.35884
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.75324
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1207
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43435
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cystic fibrosis	GWASdb SNP-Disease Associations	1.0	1.6943
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247709
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36167
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3636
yap1_18413746_mcf10a_gof_human_gpl570_gds3220	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.721845
Helicobacter Pylori (H. Pylori) Infection In Conditions Classified Elsewhere And Of Unspecified Site	DisGeNET Gene-Disease Associations	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	9.75213
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857239
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053763
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30725
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNSH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56896
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
combined t cell and b cell immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.474498
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9882
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05346
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.103
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.929415
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1855
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09789
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055411
intracellular part	GO Cellular Component Annotations 2015	1.0	null
BECKER	DepMap CRISPR Gene Dependency	1.0	3.59989
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
nucleus	GO Cellular Component Annotations 2025	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5441
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
GSE202434,GSE202438_2_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15602
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11097
nucleus	GO Cellular Component Annotations 2023	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.65027
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12901
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC15	CCLE Cell Line Gene Expression Profiles	1.0	1.64783
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141585
renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.295132
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3371
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.982
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9225
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93168
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55551
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971836
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUGC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.663
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.20419
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5948
Synovial sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Perturb_6608_KO_STK11_ERP124775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.3979
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9981
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9941
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056444
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7889
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341495
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Perturb_7781_KD_HNRNPU_SRP019270	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.0478
HC-92-HE59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241537
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8123
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1954	CCLE Cell Line Gene Expression Profiles	1.0	1.3603
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41856
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
non-small cell lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.726929
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
External side of cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.809
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4622
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R8-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Raynaud-Claes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0132
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256795
Lung squamous cell carcinoma_LUSC_TCGA-56-8504-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenosquamous carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.699
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.152
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67733
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.6526
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58979
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60397
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0014
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EW16	DepMap CRISPR Gene Dependency	1.0	5.59833
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36442
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Irritable Bowel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.98553
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.40174
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.87876
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59348
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044327
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.687592
NCIH1355	DepMap CRISPR Gene Dependency	1.0	9.32956
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303427
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68904
hsa-miR-520h	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
SKN3	DepMap CRISPR Gene Dependency	1.0	9.02695
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8413
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88139
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5782
Perturb_6702_KD_PLAGL2_SRP164912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EBC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0574
NCIH841	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Lung squamous cell carcinoma_LUSC_TCGA-85-A53L-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5232
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	1.95418
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.84396
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986963
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061158
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intestinal obstruction	GWASdb SNP-Phenotype Associations	1.0	1.56399
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24024
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1913
KYSE220	DepMap CRISPR Gene Dependency	1.0	2.54157
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4781
Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7943_KO_MED12_SRP201365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.61164
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38836
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.52426
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Gastric corpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
SNU16	DepMap CRISPR Gene Dependency	1.0	3.94295
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055163
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
deafness-intellectual disability, Martin-Probst type syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.41925
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6156
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1922
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23707
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4476
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289582
MB-50-ZI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209667
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4123
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MDAMB231_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.72272
TCF7L2_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
MCM8-MCM9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
NK-92 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5936-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.03255
RAD21	ENCODE Transcription Factor Targets	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077229
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63112
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88139
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943535
AA-23-FM46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313852
Pyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.82812
EBV-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63861
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59023
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48769
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.76114
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK12	Kinase Library Serine Threonine Kinome Atlas	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58904
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045663
kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.226952
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.926756
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8881
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4814
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11097
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061173
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null