association	dataset	threshold value	standardized value
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9693
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3872
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936455
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00034
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2471
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31518
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9107
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909671
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847448
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1116
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35815
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846457
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9207
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0952
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.039
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43257
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6327
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.2114
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862207
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83136
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6132
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00416
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7895
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950195
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68574
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10741
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7241
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84946
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.14094
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2298
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07333
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0165
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838262
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2204
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2986
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9545
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.71129
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4495
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7903
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7248
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32186
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62928
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37148
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.23516
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0732
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6634
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77941
chr7_144109595_C_A_b38	GTEx eQTL 2025	1.0	1.471
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.538
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878173
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939411
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3766
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7624
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Platelet alpha granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.831993
GSE234647_0_v_2_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25017
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2283
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942599
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3891
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3387
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1562
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2251
GSE186739_0_v_1_asic3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7591
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06944
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4106
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01021
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7907
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831265
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7682
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05111
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7854
CRCGN016_MCF10A.TP53.M_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21219
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01332
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.861
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18442
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.77521
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.236
chr7_144174943_G_A_b38	GTEx eQTL 2025	1.0	1.18133
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5907
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8271
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964195
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862653
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0428
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9916
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9168
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7068
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10249
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2063
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14489
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0137
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03879
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.08615
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965905
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.10656
skin	HPA Tissue Protein Expression Profiles	-1.0	-0.75655
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1025
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9448
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.746
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.017
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8944
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.60295
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4589
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871038
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5143
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5006
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983451
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847824
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55075
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.70905
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02274
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70043
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.14757
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.45403
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.37144
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.13333
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01852
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9811
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20111
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97229
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2408
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2205
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86304
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2378
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.978
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83482
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0541
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13494
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4099
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55106
GSE193993_4_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9773
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.001
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0142
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3898
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14821
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.637
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1267
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87175
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0395
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.06535
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97265
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9375
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2323
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993545
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7349
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3534
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08344
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877868
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2722
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8364
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4102
19749798-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.169
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0186
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02061
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.2215
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1618
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.2683
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4051
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7199
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22154
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58484
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9559
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01457
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2003
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1572
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7872
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.53651
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852674
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4234
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10351
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1971
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65427
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9293
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.01641
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.874816
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21252
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0334
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915905
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.13333
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6468
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31926
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2264
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95065
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45764
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9112
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4865
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34004
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30086
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896444
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7795
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6662
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90465
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.896053
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.03325
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8812
CRCGN015_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09395
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7284
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7229
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86182
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6436
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50801
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1245
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14815
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945893
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5398
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5477
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4973
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39055
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8425
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.552
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.34795
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.5913
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1087
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.392
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4353
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3038
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915376
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9478
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4904
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.61335
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907053
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8926
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.7761
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2144
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12064
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77682
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6133
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.20813
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9043
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834527
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5945
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00425
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.19299
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0439
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914174
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906439
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.29889
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0743
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897092
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.562716
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1063
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6179
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4413
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06331
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2624
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5157
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17727
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854776
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
19749798-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24111
GSE227698_5_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9361
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12741
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1029
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39225
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840681
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79415
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.20691
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8486
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5524
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0833
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4764
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5889
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SELENOI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41635
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.773
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4784
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.575
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26775
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842001
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31098
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.068
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45135
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5146
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2929
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein secretion	GO Biological Process Annotations 2023	1.0	null
Insect tracheal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9792
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5016
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39165
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7683
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8804
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5738
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8571
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7637
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6997
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.192
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.466
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926045
Golgi vesicle transport	GO Biological Process Annotations 2023	1.0	null
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.643
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0516
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835976
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2115
18757322-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.458
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22846
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837237
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5984
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5163
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54445
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4046
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02159
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2254
protein secretion	GO Biological Process Annotations 2025	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0888
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7487
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79473
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5173
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0219
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8548
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868571
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2167
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8435
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46484
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4717
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.931175
chr7_144102595_AT_A_b38	GTEx eQTL 2025	1.0	1.9689
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1836
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835403
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868112
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939656
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.267
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8771
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1864
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00007
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.149
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05867
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9874
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1125
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10389
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41246
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.13333
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.829332
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2494
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7332
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8697
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35975
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3466
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19738
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01357
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09224
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3821
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.466
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3053
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6267
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4985
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.12
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1993
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975718
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2759
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874586
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7146
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5085
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1655
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.43095
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935245
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58922
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.06467
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16878
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989481
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888851
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.21
CRCGN011_HEPG2_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19763
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40527
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19882
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19025
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
vesicle cargo loading	GO Biological Process Annotations 2023	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.2061
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8605
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951566
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16435
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.465
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0137
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9615
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6914
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01958
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833866
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.874816
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51896
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04947
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7141
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01388
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0478
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0893
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907532
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8704
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40321
chr7_144171477_G_A_b38	GTEx eQTL 2025	1.0	1.94698
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.126
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05584
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3162
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6635
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91039
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27313
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15717
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.13333
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3169
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41781
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868532
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6566
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum exit site	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2886
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8079
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.23357
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51906
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943136
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16693
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16913
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0614
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.908
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2796
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24944
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13598
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1299
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.5913
GSE158438_2_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5833
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15807
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.87482
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4935
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.34035
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5533
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7789
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43417
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.815
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3047
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7359
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein transport	GO Biological Process Annotations 2025	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.998
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.58908
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930939
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.13333
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	2.31385
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7465
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45746
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9338
membrane part	GO Cellular Component Annotations 2015	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.972335
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31956
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9299
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43289
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946279
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.41955
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.583
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1441
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4573
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85746
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9646
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0288
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2832
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0232
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2959
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.362
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6389
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32566
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5148
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
protein transport	GO Biological Process Annotations 2023	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.746
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33414
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.379
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1035
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.30193
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8309
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3713
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8273
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2127
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06309
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19517
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.008938
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36128
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13311
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964523
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5841
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3721
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5526
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52104
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3711
chr7_144096458_A_AAAAT_b38	GTEx eQTL 2025	1.0	2.74039
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846598
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950993
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5207
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2965
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18193
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882381
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36545
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23602
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6142
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73831
CRCGN011_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00163
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900217
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8041
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918207
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4287
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5485
establishment of protein localization to extracellular region	GO Biological Process Annotations 2025	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5731
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971664
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53898
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1161
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02567
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1021
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8024
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1714
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.936281
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30092
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0319
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.962223
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.47267
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08882
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6009
17880687-TableS3	GeneSigDB Published Gene Signatures	1.0	null
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0057
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6502
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70864
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8847
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938826
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1111
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85951
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862374
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34032
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1377
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7775
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.63633
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849488
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1044
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5489
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4418
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8089
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5723
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0949
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5282
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4554
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1926
establishment of protein localization to extracellular region	GO Biological Process Annotations 2023	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31654
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2279
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7019
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8958
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.72646
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2745
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3246
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
endoplasmic reticulum to Golgi vesicle-mediated transport	GO Biological Process Annotations 2025	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6705
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	0.87367
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1591
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03415
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9949
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2191
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06295
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.898048
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4121
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3003
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995752
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9173
17234769-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3592
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8131
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5111
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.37276
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925271
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2472
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3805
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08083
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6011
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4801
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.81876
GSE117212,GSE117214_2_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833027
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36391
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6135
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0159
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01733
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844235
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48661
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0165
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6943
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970647
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45688
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.21539
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5291
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36655
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1761
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903273
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961637
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.252
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.116433
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40085
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1062
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2694
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1184
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845326
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3882
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1376
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00119
GSE193351_4_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0249
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65564
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.13333
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4719
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3553
GSE186460_0_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0727
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4998
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863364
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25683
shsy5y	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8178
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7262
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13006
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9395
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5479
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9168
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.913549
endoplasmic reticulum to Golgi vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.16471
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6189
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954147
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53406
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914248
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0808
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.746
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9889
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03987
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955883
chr7_144095898_G_A_b38	GTEx eQTL 2025	1.0	1.18255
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8899
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7127
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0078
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4213
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24325
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.44585
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3364
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.062
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11234
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0574
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86504
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1995
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15813
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852983
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3592
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5027
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7432
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4752
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00308
a431	HPA Cell Line Gene Expression Profiles	1.0	1.26285
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2416
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4643
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07034
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6631
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08646
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1712
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8296
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4692
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06637
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00225
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5796
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8491
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33022
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2798
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21987
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83499
PMC12335956-BNEO_NEO-2024-000529-mmc1.xlsx-4_chr7essentials_published-THP1_Wang_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.04479
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35105
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4525
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5369
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9944
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.17557
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6018
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2012
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9976
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57601
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8112
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1295
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945574
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0352
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8868
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6826
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5562
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830523
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0