association	dataset	threshold value	standardized value
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49021
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939891
Perturb_10681_KO_Gtf2ird1_SRP074330	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.15964
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.21121
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91956
heme binding	GO Molecular Function Annotations 2023	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877326
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066168
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7053
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36312
PHA-00745360-3827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clinicopathological	GeneRIF Biological Term Annotations	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.86168
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.337
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04924
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04288
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848331
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06178
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A80010944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18462
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K63779242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69416
K562	BioGPS Cell Line Gene Expression Profiles	1.0	0.858093
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29449
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0328
biotin-6689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
crc	GeneRIF Biological Term Annotations	1.0	null
Perturb_2599_OE_PTH1R_SRP132981	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.21
benzamil-4294	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mebendazole-2300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59612
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05533
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11004
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-558	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6915
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063966
benperidol-4781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7511
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12833
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.85374
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5277
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980617
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990495
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
beta-escin-2194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Defective CYP1B1 causes Glaucoma	Reactome Pathways 2014	1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Down Syndrome_Brain_GSE5390	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.63639
Retinoic acid	MW Enzyme Metabolite Associations	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861146
thioperamide-5270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.4622
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.52294
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05017
SHI1	DepMap CRISPR Gene Dependency	1.0	3.17642
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.52218
colorectal	GeneRIF Biological Term Annotations	1.0	null
BRD-K92440102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05274
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K28598371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67564
bemegride-3051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sw-480 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
BRD-K40432489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68261
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3075
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95359
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.76723
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23923189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93101
oxetacaine-1484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	GO Molecular Function Annotations 2015	1.0	null
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytochrome P450	InterPro Predicted Protein Domain Annotations	1.0	null
PRDM5-23873026-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381003
BRD-K46655163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40513
BRD-K64663625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07711
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.08848
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029277
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866026
BRD-K79627231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03133
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12229
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11874
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02393
population	GeneRIF Biological Term Annotations	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.12737
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26094
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4169-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.13299
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10692
CEBPB	ENCODE Transcription Factor Targets	1.0	null
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	3.93391
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76896
BRD-K73430970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08787
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36977
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
p450	GeneRIF Biological Term Annotations	1.0	null
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2092
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867885
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63935
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchopulmonary sequestration	GWASdb SNP-Phenotype Associations	1.0	0.969142
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1814
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990791
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.79761
BRD-K09711841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06606
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82989
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61868194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43048
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01534
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.06815
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049578
treatment	GeneRIF Biological Term Annotations	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83623
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19813
NCIH23	DepMap CRISPR Gene Dependency	1.0	3.8793
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933445
KLF2_01_226	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90294
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0558
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13257316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15834
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34911
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.849
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18702
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56682
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83097
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79752
DAOY	CCLE Cell Line Gene Expression Profiles	1.0	1.39365
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.183494
therapy	GeneRIF Biological Term Annotations	1.0	null
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876423
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01468
Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)	Reactome Pathways 2014	1.0	null
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
susceptibility	GeneRIF Biological Term Annotations	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.6561
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00381
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70691
BRD-K60905390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88824
organic heteropentacyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906864
LN443	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2117
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28251
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887899
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971953
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42202
BL2366 (KIAA0528)	NURSA Protein Complexes	1.0	null
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7038
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997544
thp1	HPA Cell Line Gene Expression Profiles	1.0	0.894035
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BCL11B_KO_GSE9330_4_mouse_brain (striatum)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BL8149 (SIPA1)	NURSA Protein Complexes	1.0	null
PRDM5-23873026-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1039
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96292
BL3061 (UBR4)	NURSA Protein Complexes	1.0	null
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02411
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80977
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03673
Perturb_4260_OE_MEIS1_SRP201342	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04476
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.62912
KMS34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38903
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.005
CerebellumPeduncles	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05068
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.72561
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30412
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
perinatal necrotizing enterocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.517649
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09139
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896597
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076542
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29599
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)	Reactome Pathways 2014	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.48618
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7967
Adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31510624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36215
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35637
MC-IXC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54987
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.01701
japanese	GeneRIF Biological Term Annotations	1.0	null
BRD-A69786436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71335
BL2569 (C17orf71)	NURSA Protein Complexes	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969291
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53615
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5617
FHL2_Deficiency_GDS3344_596_mouse_Spontaneously immortalized embryonic fibroblasts (EFs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934448
Perturb_15390_KD_E2F1_SRP399677	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.11803
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single	GeneRIF Biological Term Annotations	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52047843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4922
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20739
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.92949
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02199688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00734
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24177
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950738
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08658
BRD-K65945126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09066
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05331
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01902
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD4	ChEA Transcription Factor Targets	1.0	null
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1744
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11151
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57565
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21499
BRD-K14139166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55687
single-organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34849
TCF7	ChEA Transcription Factor Targets	1.0	null
Bronchopulmonary dysplasia	GWAS Catalog SNP-Phenotype Associations	1.0	0.129504
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7864
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50898
A673	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4889
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
MOLT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68992
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
JMURTK2	DepMap CRISPR Gene Dependency	1.0	2.57188
Biological oxidations	Reactome Pathways 2014	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23465
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4774
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR8	CCLE Cell Line Gene Expression Profiles	1.0	1.4872
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02689
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
C3A	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02156
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.24757
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42114
BL6869 (CEP192)	NURSA Protein Complexes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW-7	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73643
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92486
(+/-)-catechin-3012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64273
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
some	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
BRD-K36804307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10082
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36948
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42121
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.641
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.21218
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489057
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18442
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13406
OAW28	CCLE Cell Line Gene Expression Profiles	1.0	1.77261
BRD-K70856965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97789
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
BRD-K04470135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41401
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02327
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6219
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59798
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91973
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5912
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00728
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986657
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951741
CORL105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87384
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885792
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
phenacetin-2471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
CRCGN008_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46075
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69655
Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)	Reactome Pathways 2014	1.0	null
etofenamate-7327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74261250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53204
tanespimycin-6185	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GFI1B	ChEA Transcription Factor Targets	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05017
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835647
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.50956
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.717838
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6429
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92223
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981275
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retinoid binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K35886478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22887
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.917611
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01754882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41978
NCI-H2171	GDSC Cell Line Gene Expression Profiles	1.0	1.45161
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08974502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5261
MT-ND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20324
zoxazolamine-6290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9527
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53142
R-atenolol-2496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29408413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12365
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20827
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10404
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173215
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4521181-oncsis201520x8.pdf-106-THAP10_THAP10	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
remoxipride-6503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70895130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34797
Pterinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20144
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0142
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88905
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.11939
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	GO Molecular Function Annotations 2025	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37469
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853921
acetylsalicylic acid-6164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838046
BRD-K35788497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55557
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93011
Cytochrome P450 - arranged by substrate type	Reactome Pathways 2014	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NP-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55379
BRD-K74314059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26629
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06614
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	4.41171
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830345
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0301
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.60323
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06635
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64123
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24414
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954567
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14338
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866535
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84529
BRD-K44624970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33515
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15891
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23934
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994966
Organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_9-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067238
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882367
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
aflatoxin metabolic process	GO Biological Process Annotations 2023	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19435
colon	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01076
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18832
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.197
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.3595
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069872
ciprofibrate-6138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.75493
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25611
Perturb_17212_KD_GRHL2C_SRP124640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4024
Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55672
BRD-K95688447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08857
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115273
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	1.35906
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
SCC-9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50407
BT16	DepMap CRISPR Gene Dependency	1.0	2.43613
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3203
POLR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28638
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70217
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5085
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38184
BRD4-C (BRD4)	NURSA Protein Complexes	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
aflatoxin metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K07813434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83617
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05022
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2634
value	GeneRIF Biological Term Annotations	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	2.12912
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926477
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.912653
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70686
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20277
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861406
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15193
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887899
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K71213946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48181
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27183
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887505
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074122
Inflammation	CTD Gene-Disease Associations	1.0	1.29996
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38778
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terguride-4633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61877191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05195
Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)	Reactome Pathways 2014	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K29525414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65076
CRCGN012_HEPG2_24H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11412
distribution	GeneRIF Biological Term Annotations	1.0	null
BRD-K12612468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20085
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69505608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41669
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47911
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468824
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932453
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0983
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849018
Perturb_7462_KD_CHERP_SRP126064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15956
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_7-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
quinethazone-4529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33381
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863083
Perturb_12524_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0643
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24554824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58574
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.534
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902996
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CP-320650-01-3822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-920-6497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5119
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82056
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05603
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87918
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophageal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
causal	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.04575
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872735
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32056
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11353
hsa-miR-504	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64534
BRD-K68463857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65642
GP2D	CCLE Cell Line Gene Expression Profiles	1.0	1.55819
GSE89154_1_v_2_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM19	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.36345
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12667
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07733
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02087
L-methionine sulfoximine-4070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fludroxycortide-2184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Oxidation by cytochrome P450	WikiPathways Pathways 2024	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49392
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19278
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27119
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.32162
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
factors	GeneRIF Biological Term Annotations	1.0	null
diterpenoid catabolic process	GO Biological Process Annotations 2025	1.0	null
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
RUNX1	ChEA Transcription Factor Targets	1.0	null
CAL-54	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72596
steroid hydroxylase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09758
phenelzine-4538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43538
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
GSE148692,GSE148695_2_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12742_KD_GOT1_SRP282058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.85098
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K99331869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14361
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.06289
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66281
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869153
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40335
NB69	DepMap CRISPR Gene Dependency	1.0	3.03897
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097798
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61914
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endoplasmic reticulum lumen	GO Cellular Component Annotations 2015	1.0	null
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.31919
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1696
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
Heme	HMDB Metabolites of Enzymes	1.0	null
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8292
differences	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1226
BRD-K37657772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33544
colorectal cancer	GAD Gene-Disease Associations	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23605
Adrenal cortex cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.828182
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835647
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1374
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04974
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92078
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1108
chrysin-6485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27236794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66507
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2266
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.89755
SOCS3_KO_GDS3149_297_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842082
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64628
PRDM5	ChEA Transcription Factor Targets	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	3.40802
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0558
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.5154
CRCGN017_MCF10A.TP53.M_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51269
Perturb_1085_KD_MYEOV_SRP242311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
JVM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45048
CRCGN016_MCF10A.TP53.M_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81549
metoclopramide-2353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	1.0	1.44898
BRD-K07928699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74829
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8985
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00263786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0915
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90529
LCLC-97TM1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54536
LC4-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14333
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885963
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957141
BRD-K62888534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40535
Rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEC1	DepMap CRISPR Gene Dependency	1.0	2.97897
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
NCIH660	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.35546
modifies	GeneRIF Biological Term Annotations	1.0	null
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09028
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.183494
promazine-2173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.083
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056575
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prilocaine-3727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04487
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60473
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18947
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49798
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4405
proxyphylline-5993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14251637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69773
bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.674135
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
KYSE-510	GDSC Cell Line Gene Expression Profiles	-1.0	-2.0181
BRD-K01723566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66804
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.525
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13408
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13271
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25322276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13432
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.491791
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07228
BRD-K22011492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02525
BC-3	GDSC Cell Line Gene Expression Profiles	1.0	2.16963
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05758
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.424
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Metapathway biotransformation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95299
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19657
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.353
BRD4-N (BRD4)	NURSA Protein Complexes	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.384
mexican	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24336
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19935
NCI-SNU-5	GDSC Cell Line Gene Expression Profiles	1.0	2.0792
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60259
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11312
Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)	Reactome Pathways 2014	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4159
Biological oxidations	Reactome Pathways 2024	1.0	null
BRD-K73025859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84736
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)	Reactome Pathways 2014	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11312
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067342
BRD-K21927299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0809
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867681
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38289
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986073
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8452
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0408
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.858
endomembrane system	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168349
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4044
mda-mb-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545342
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47281
BRD-K16673836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0181
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.51152
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.80419
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
kawain-2337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
BRD-K59263278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5197
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47702
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01531
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34897
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3693
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20417
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K19575490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01947
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.12944
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34897
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29171
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849777
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05036
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TBC1D16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32665
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	1.72174
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
detect	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10752
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IPC-298	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42382
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71748
those	GeneRIF Biological Term Annotations	1.0	null
BRD-K77203880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07152
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02135
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27347
adrenal gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.512648
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72224
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36539857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23729
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85188
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70485
CP-690334-01-4383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4496
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029247
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUTU-80	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58676
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22619
retinoic acid catabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956525
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61702
tiabendazole-2479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08255
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.043
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963345
tonzonium bromide-4617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35716
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68202
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990791
BRD-K91564773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3629
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB1_KD_GSE50532_641_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07738
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85756
endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
exogenous drug catabolic process	GO Biological Process Annotations 2015	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.678701
BRD-K65320638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18933
Perturb_522_KD_MAVS/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.07305
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17324
hypomethylation	GeneRIF Biological Term Annotations	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tropicamide-3722	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35448
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
tetrapyrrole binding	GO Molecular Function Annotations 2015	1.0	null
tanespimycin-1159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20853228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59171
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.126
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06636
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126269
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS180	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64871
BL2272 (TCF12)	NURSA Protein Complexes	1.0	null
CRCGN009_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23372
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85216
CRCGN011_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1366
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057087
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85406
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Enterocyte_Large intestine_Human	CellMarker Gene-Cell Type Associations	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2294
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55599
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8289
BRD-K92059157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35694
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00708
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1622
MHH-PREB-1	GDSC Cell Line Gene Expression Profiles	1.0	1.6053
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30849
Phase I - Functionalization of compounds	Reactome Pathways 2024	1.0	null
Retinol metabolism	KEGG Pathways 2026	1.0	null
endoplasmic reticulum lumen	GO Cellular Component Annotations 2025	1.0	null
A7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960602
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
paromomycin-3017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
organophosphate metabolic process	GO Biological Process Annotations 2025	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95197
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90948
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	2.11982
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041123
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0466
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U1-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5548
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04812
active	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35956
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16243
Zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2848
BRD-K35413741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00649
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
clindamycin-7172	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.904465
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
CRCGN015_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1464
meclofenoxate-3707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Defective FMO3 causes Trimethylaminuria (TMAU)	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2475
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93882
BRD-K35174435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07105
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0702
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metapathway biotransformation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79529
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC9585724-12916_2022_2610_MOESM2_ESM.xlsx-ST12_-_MediationRatioStromalSCT-Unnamed_5_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.886219
products	GeneRIF Biological Term Annotations	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37479727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15268
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39061
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.3714
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11517
BRD-K38719699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03748
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K90485414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23931
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.25
organic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02975
crotamiton-3050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34332
among	GeneRIF Biological Term Annotations	1.0	null
CGTH-W-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56361
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314409
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14068
BRD-K64329997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05245
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087192
Endoplasmic reticulum lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3507
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10944
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00645
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7495
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16838
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
BRD-K98537764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13176
YY1	ENCODE Transcription Factor Targets	1.0	null
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07661
CTCF	ENCODE Transcription Factor Targets	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.50913
flunixin-3713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_8-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87613
Oxidation by Cytochrome P450(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857466
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19012
BRD-K42333498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21207
phosphate-containing compound metabolic process	GO Biological Process Annotations 2025	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6622-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ficolin-1-rich granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
OVTOKO	DepMap CRISPR Gene Dependency	1.0	5.459
BRD-K74879991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1376
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07909
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.578
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77254
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30896
BRD-K77150932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30311
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50583
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17144
geldanamycin-1169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.82549
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
eticlopride-3056	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H295 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18767
pyrazinamide-2839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82104
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10042
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52686
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68535
SOX4_01_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.62246
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854025
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65436
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.4219
monooxygenase activity	GO Molecular Function Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075221
all-trans retinal binding	GO Molecular Function Annotations 2023	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.770027
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00706
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.914315
BRD-K26187220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42298
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.03231
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56632
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.6149
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91335
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15243
pilot	GeneRIF Biological Term Annotations	1.0	null
BRD-K82460510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35967
BL322 (MLH1)	NURSA Protein Complexes	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
genotypes	GeneRIF Biological Term Annotations	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05731
BRD-K81660107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5151
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45243
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.760742
hsa-miR-5095	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86525
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92398
Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3125
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.06049
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4248
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45031
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40897
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05782
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18798
all-trans-retinol binding	GO Molecular Function Annotations 2023	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.08733
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2646
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85559
HSC4	CCLE Cell Line Gene CNV Profiles	1.0	1.37817
BRD-K04877855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24738
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.928
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47292
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13401
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)	Reactome Pathways 2014	1.0	null
valuable	GeneRIF Biological Term Annotations	1.0	null
fulvestrant-6197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KM12	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.76894
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37025
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03317
REST	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11846991-41598_2025_90195_MOESM1_ESM.pdf-11-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10732
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14412
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14996
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_499_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.98912
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9565
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
benzocaine-2167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.08479
monocarboxylic acid binding	GO Molecular Function Annotations 2023	1.0	null
hsa-miR-4290	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytochrome metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K25147028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02537
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2468
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44247
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75568
BRD-K27458941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17779
SF268	BioGPS Cell Line Gene Expression Profiles	1.0	0.936929
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47724
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12347
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36778976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05797
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZB-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042909
enhanced	GeneRIF Biological Term Annotations	1.0	null
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25578
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.51929
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18431
retinal binding	GO Molecular Function Annotations 2025	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.14275
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54342
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08755
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995112
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
six	GeneRIF Biological Term Annotations	1.0	null
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34717
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53472
BRD-K77074748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2941
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30117
drug catabolic process	GO Biological Process Annotations 2015	1.0	null
Phase 1 - Functionalization of compounds	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A_48H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70632
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34485
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.980584
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchopulmonary dysplasia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
skin	HPA Tissue Gene Expression Profiles	1.0	1.19307
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15343
BRD-K42757676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43302
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.37171
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07167
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.67224
NCIH661	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10028
normal	GeneRIF Biological Term Annotations	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0033
nitrofural-2459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA46	GDSC Cell Line Gene Expression Profiles	1.0	1.49251
BRD-K38630090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03879
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111665
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22304
CRCGN015_MCF10A.TP53.M_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3228
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610541
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23271
BRD-K08929846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38504
metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1788
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25969
Cytochrome P450, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07153
lipid metabolic process	GO Biological Process Annotations 2025	1.0	null
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73155
OELE	CCLE Cell Line Gene Expression Profiles	1.0	1.66678
C3A	GDSC Cell Line Gene Expression Profiles	1.0	2.3859
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05017
Perturb_12523_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20012501-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.149632
TAF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0364
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10802
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.0079
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57996
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59598
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69853
BRD-K00323141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45447
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19077
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890602
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041579
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.936625
cyclothiazide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59502
BRD-K81199760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09011
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16838
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04053
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-972-6511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73643
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29043
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02929
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45089
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.104483
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01213
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882231
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46806
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	GO Molecular Function Annotations 2023	1.0	null
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07762528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03457
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88491
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897848
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0574
hacat	HPA Cell Line Gene Expression Profiles	1.0	0.877259
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10238
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952415
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08422
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0763
aflatoxin	GeneRIF Biological Term Annotations	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4197
BRD-K20428189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03303
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.994514
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25658
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90088
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647721
tcf3_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.680774
cation binding	GO Molecular Function Annotations 2015	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A_48H:I22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02331
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19197
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998985
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	2.40876
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methylation	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042164
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8095
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12727
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35448
BRD-K50424430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32777
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051734
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21489
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7649
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4035
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9283
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.005473
BRD-K99807388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36483
ROS50	DepMap CRISPR Gene Dependency	1.0	5.42614
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.01993
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60112
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36705
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19547
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054923
BRD-K23112275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06215
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62786
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01972
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oxidation by Cytochrome P450(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0292
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.3714
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2474
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20658
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836987
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20301
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.3721
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405555
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993792
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882367
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05503
BRD-K34254821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12694
oxygen binding	GO Molecular Function Annotations 2015	1.0	null
Defective CYP19A1 causes Aromatase excess syndrome (AEXS)	Reactome Pathways 2014	1.0	null
clopamide-5402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K92444813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01631
Meprin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74649
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8456
Perturb_16529_OE_Plagl2_SRP150086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7056
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931084
Miscellaneous substrates	Reactome Pathways 2024	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04586
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51332
aflatoxin b1 metabolic process	GO Biological Process Annotations 2015	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
felbinac-3061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47806
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.43
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0111
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
BRD-K14970242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39936
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K18494310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61626
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968482
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29588
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06059
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258243
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95455
CRCGN014_HEPG2_3H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19836
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10788
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4523
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55319
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862046
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36243
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39845
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26177
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26983
Metabolism	Reactome Pathways 2024	1.0	null
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05768
BL2754 (LCOR)	NURSA Protein Complexes	1.0	null
HCC-2998 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851706
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.672722
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43473
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98543
BRD-K36807301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99905
Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small_Intestine-intestinal crypt stem cell of small intestine	Tabula Sapiens Gene-Cell Associations	1.0	1.11424
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903542
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.87959
BRD-K05074020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37737
Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)	Reactome Pathways 2014	1.0	null
Perturb_11584_Mut_TRIM28_SRP212102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3614
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A81392774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2254
fat-soluble vitamin catabolic process	GO Biological Process Annotations 2025	1.0	null
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
BRD-K32723442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26
talampicillin-7014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
spiramycin-2558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hydroxylamine	CTD Gene-Chemical Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1724
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02382
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40081
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
citiolone-2176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
retinal binding	GO Molecular Function Annotations 2023	1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43075
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08506
BRD-K57620855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68633
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K72754669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60408
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089326
Liver enzyme levels (gamma-glutamyl transferase)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3301
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tiaprofenic acid-2492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chr7_1074376_C_T_b38	GTEx eQTL 2025	1.0	3.67634
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35712
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301039
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864633
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20325
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845144
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
adult	GeneRIF Biological Term Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
CHLA15	DepMap CRISPR Gene Dependency	1.0	2.02009
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC1359	CCLE Cell Line Gene Expression Profiles	1.0	1.41431
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
furaltadone-2554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organic heteropentacyclic compound metabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949951
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60493
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
hsa-miR-608	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91484
CRCGN015_MCF10A.TP53.M_24H:J09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22195
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42858
KP2	DepMap CRISPR Gene Dependency	1.0	7.48786
BRD-K26163290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42259
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11948025-ADVS-12-2416484-s001.pdf-118-ENSG00000136574_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10981
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
HCC827	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09117
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1251
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27468
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
M059J	GDSC Cell Line Gene Expression Profiles	-1.0	-3.00753
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.04352
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32087
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RB-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12683
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04885
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0935
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.61697
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61591
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850747
CEBPD	ENCODE Transcription Factor Targets	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966652
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16177
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6386
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02993
2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole	CTD Gene-Chemical Interactions	1.0	null
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70915
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW579	DepMap CRISPR Gene Dependency	1.0	3.27887
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56865
hutu80	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
COLO783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2963
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30843
UOK101	Achilles Cell Line Gene Essentiality Profiles	1.0	2.34663
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0625
BRD-K41207293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25268
BRD-K38633800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79941
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80224
CRCGN015_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1476
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844845
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831559
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.655859
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.19707
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17689
BRD-K31778735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61048
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5561
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	7.71662
Perturb_15418_OE_KDM4B_SRP194543	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.56491
terguride-5400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02436
BL1045 (ABL2)	NURSA Protein Complexes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETFDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18966
binding	GO Molecular Function Annotations 2015	1.0	null
mRNA_SUZ12_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
chr7_1020448_A_C_b38	GTEx eQTL 2025	1.0	3.62809
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	190.683
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74174
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0156
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22247
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21933068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49798
SMC3	ENCODE Transcription Factor Targets	1.0	null
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0942
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7797
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058831
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05777
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18627
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896858
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997317
Colorectal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05533
BRD-K76426411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01531
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854885
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14132
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05386
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
Mean spheric corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6844
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21582
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
eldeline-3925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	2.65479
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
Intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12471
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.726162
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52141
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886268
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887899
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040944
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16794_KD_SPIN1_SRP171066	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55379
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6504
Cytosolic aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.913
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3257
Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)	Reactome Pathways 2014	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88249
PWR-1E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHH-CALL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54814515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28675
BRD-K91361836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45384
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23641
BRD-K68916730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03809
BRD-K26335565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10921
BRD-K60895802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04855
suramin sodium-7501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27914
molecular_function	GO Molecular Function Annotations 2015	1.0	null
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.918024
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.31775
NEC8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54027
BRD-K23296676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09158
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26357
Perturb_3417_KO_Cdx2_SRP093647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Prestwick-674-2179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45506
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859145
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2885
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.90626
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70765
NCIH1975	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01251
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4997
BRD-K71452779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31535
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41571
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2304
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41185
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166544
haloperidol-6163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
retinol binding	GO Molecular Function Annotations 2023	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83942575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10164
BRD-K38494391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12621
BRD-K69480055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45587
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-674-3716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49907
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96505
Adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65476
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055967
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970479
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964229
CRCGN009_HEPG2_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29464
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2729
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.519
BRD-K65291993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06519
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	6.54396
fetal	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01273
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TZ-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8499
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.886286
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2344
TEAD4	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.38775
PMC11555823-supplementaltable4_ddae135.xlsx-Sheet1-Genes_inversely_regulated_between_MDS_and_RTT_iNeurons_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1033	CCLE Cell Line Gene Expression Profiles	1.0	1.90029
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28904
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11312
BRD-K26904107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63091
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84817
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00288
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8754
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7479515-mmc8.xlsx-ST-RELA-variable-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22093396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43382
Perturb_500_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.22954
CRCGN017_MCF10A.TP53.M_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3471
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0155
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984663
Bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38798
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92789454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58328
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01904
doxepin-6337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52767
BRD-K65266979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11884
BCL11B_KO_GDS3178_296_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)	Reactome Pathways 2014	1.0	null
L363	Achilles Cell Line Gene Essentiality Profiles	1.0	1.4379
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78015
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1753
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04159
BRD-K29662535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64948
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834531
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17892
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37148
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08759542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84147
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_498_KD_MAVS/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46523
retinol binding	GO Molecular Function Annotations 2025	1.0	null
Perturb_16530_OE_Plagl2_SRP150086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05471
BL5312 (HMGN1)	NURSA Protein Complexes	1.0	null
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
TK-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
hsa-miR-628-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Small_Intestine-intestinal crypt stem cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0247511
drug metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7723
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1377
BEN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4914
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
BL2041 (XRN2)	NURSA Protein Complexes	1.0	null
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0911
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68239
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894428
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6823-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28003
breast	GeneRIF Biological Term Annotations	1.0	null
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962352
BRD-K73952959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53667
A204	BioGPS Cell Line Gene Expression Profiles	1.0	1.43338
KYSE-270	GDSC Cell Line Gene Expression Profiles	-1.0	-2.38461
ether metabolic process	GO Biological Process Annotations 2015	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20088
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
CRCGN015_MCF10A.TP53.M_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.697
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968482
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
BRD-K12003101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6359
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.45004
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00659
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05918
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829463
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69224
oxidation	GeneRIF Biological Term Annotations	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903542
EPI-1625-1 (ITK)	NURSA Protein Complexes	1.0	null
BRD-K38610362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20065
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12152
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42336
Metabolism	Reactome Pathways 2014	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.60921
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25748
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6825
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85179
azaperone-6151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61869
gland	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52435
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33827
status	GeneRIF Biological Term Annotations	1.0	null
however	GeneRIF Biological Term Annotations	1.0	null
nefopam-3730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16278
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54404
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044499
BRD-K05605336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11965
Prestwick-864-2994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
benzamil-2200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0833
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16847
BRD-K25075258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38115
membrane-enclosed lumen	GO Cellular Component Annotations 2015	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90072
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
Perturb_13923_KD_DDX5/DDX17_SRP335223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9442
decamethonium bromide-4094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907368
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83351
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30576
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
retinoid binding	GO Molecular Function Annotations 2023	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12495
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Cytochrome P450 - arranged by substrate type	Reactome Pathways 2024	1.0	null
BRD-A24524033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59928
BRD-K01991250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37983
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941651
betaxolol-4608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76344
BRD-K64665523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.316
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98269
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K64091938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03048
PCDHB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55891
chenodeoxycholic acid-6012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17251
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7429
biperiden-2460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03296
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3057
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12047
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.825
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.10312
levopropoxyphene-2980	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953071
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897067
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041719
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915927
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942173
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.42735
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58096
indicating	GeneRIF Biological Term Annotations	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01211
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43509
monocarboxylic acid binding	GO Molecular Function Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03659510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55412
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84695
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.02846
BRD-K41035516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41433
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7083
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.03231
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932189
electron	GeneRIF Biological Term Annotations	1.0	null
BRD-K83115435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21508
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7519
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90185
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.983062
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RD	DepMap CRISPR Gene Dependency	1.0	3.26617
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31056
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32248
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30599
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438356
SNU738	CCLE Cell Line Gene Expression Profiles	1.0	1.47846
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
etidronic acid-4387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5312
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16823
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21044
SOCS3_KO_GDS3149_8_mouse_multiple cell types	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27638
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.1279
Perturb_9238_KD_ENL_SRP074134	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.0071
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02101
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.0555
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03381
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	7.54054
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6951
BRD-K29264158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50519
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08331
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835222
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25932
ELOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06848
meteneprost-7504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-685-2188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytochrome	GeneRIF Biological Term Annotations	1.0	null
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867835
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74751
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27603
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3654
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11762
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.38839
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01228
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29598
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44736
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64047
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.59772
BRD-K71420819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16041
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725393
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12526
GCIY	DepMap CRISPR Gene Dependency	1.0	2.22395
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.9312
hcc	GeneRIF Biological Term Annotations	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0588
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00907
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894544
neoplasms	GeneRIF Biological Term Annotations	1.0	null
BRD-K31678817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48709
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57802
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.24974
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Xenobiotics	Reactome Pathways 2014	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9137
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93607
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.89369
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057704
cellular process	GO Biological Process Annotations 2015	1.0	null
BCB000040-7488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05484
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1754
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
15902281-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BL9238 (GREB1)	NURSA Protein Complexes	1.0	null
BRD-K63436783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05422
BRD-K72135113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33116
CRCGN017_MCF10A.WT.HP_24H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.132
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
C2BBE1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0588
Perturb_1079_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K19699893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17485
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6525
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33255
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02748
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892981
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31455
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19484
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274744
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05789
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98083
BRD-K38170103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96626
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01103
BRD-K22478004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73188
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25658
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6625
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.2264
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K02747732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17256
COLO741	Achilles Cell Line Gene Essentiality Profiles	1.0	1.35603
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92203
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70129
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074821
KATOIII	CCLE Cell Line Gene Expression Profiles	1.0	1.97333
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
ethoxyquin-2559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21176
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K14850613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13511
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86224
Adrenocortical carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835082
HS695T	DepMap CRISPR Gene Dependency	1.0	3.54077
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338914
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1889
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fenoterol-5432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49011
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4512
xenobiotic metabolic process	GO Biological Process Annotations 2015	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1052
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.3714
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
calcium pantothenate-4189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
monocarboxylic acid catabolic process	GO Biological Process Annotations 2025	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52005
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.625
BRD-K36883526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32375
EPI-2064-1 (ERBB2)	NURSA Protein Complexes	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51501
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55679
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6397
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81322
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84164
iron ion binding	GO Molecular Function Annotations 2015	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	166.136
D502MG	DepMap CRISPR Gene Dependency	1.0	5.94485
aflatoxin metabolic process	GO Biological Process Annotations 2025	1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131317
biological_process	GO Biological Process Annotations 2015	1.0	null
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10902
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.5782
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9080_KD_FGFRL1_SRP319532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.74749
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1159
BEAS-2B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
UHO1	DepMap CRISPR Gene Dependency	1.0	2.02656
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65652
phosphate-containing compound metabolic process	GO Biological Process Annotations 2023	1.0	null
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.841
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34279
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04371
SCC4	DepMap CRISPR Gene Dependency	1.0	4.19793
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.41801
hyoscyamine-5524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04446
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14742
transfer	GeneRIF Biological Term Annotations	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.77712
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.006
phenothrin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31347
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K29571884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03683
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90302
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19027
moracizine-6000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.5897
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01089
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.510728
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0629
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78667
Perturb_525_KD_TLR3/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.13816
toxin metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K61796560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65413
MYC	ENCODE Transcription Factor Targets	1.0	null
DoTc2-4510	GDSC Cell Line Gene Expression Profiles	1.0	1.73285
TE9	CCLE Cell Line Gene CNV Profiles	1.0	2.17499
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05761
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70015
BRD-K97445906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41294
BAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02793474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05219
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989606
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colonic	GeneRIF Biological Term Annotations	1.0	null
Perturb_9243_KD_ENL_SRP074134	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.6576
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.23264
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
Lung squamous cell carcinoma_LUSC_TCGA-21-5786-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999066
NIX_Deficiency_GDS2630_655_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.611229
Prostate-hillock cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	1.11424
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888832
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04561
BRD-K06220918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45088
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14055
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874733
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5173
PMC7479515-mmc8.xlsx-ST-RELA-variable-Unnamed_1_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr7_979332_G_C_b38	GTEx eQTL 2025	1.0	11.8922
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18122
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20775
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K00631971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04887
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96951
Brain Lower Grade Glioma_LGG_TCGA-DU-6395-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0822
Defective MAOA causes Brunner syndrome (BRUNS)	Reactome Pathways 2014	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.6346
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32566
benzthiazide-2989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.648
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61338
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41435
CCRF-CEM	GDSC Cell Line Gene Expression Profiles	-1.0	-2.00227
SW756	DepMap CRISPR Gene Dependency	1.0	3.56367
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-dORF6_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44358
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964229
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9396
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06727
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088263
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
lorglumide-5254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mycotoxin metabolic process	GO Biological Process Annotations 2023	1.0	null
diterpenoid catabolic process	GO Biological Process Annotations 2023	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937037
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4707
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.002
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31744
seems	GeneRIF Biological Term Annotations	1.0	null
Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)	Reactome Pathways 2014	1.0	null
rescinnamine-4386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09457
BL6350 (ATF7)	NURSA Protein Complexes	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
agreement	GeneRIF Biological Term Annotations	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59427
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17925
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82945
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1792	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2981
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06846
Prestwick-857-3016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47793
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0048
CYB5A	Pathway Commons Protein-Protein Interactions	1.0	null
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
metabolism	GeneRIF Biological Term Annotations	1.0	null
BRD-K39179354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02901
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65609
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72717
all-trans retinal binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00107
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Insomnia symptoms (never/rarely vs. usually)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33407
BL6899 (CEP76)	NURSA Protein Complexes	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H11A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06265
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949422
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74476
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939891
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963379
MOLT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56656
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2709
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05974
nialamide-3871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059431
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861275
common	GeneRIF Biological Term Annotations	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45647
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31584
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72212
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965496
BRD-K34640380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5244
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
tissue	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40971
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86193
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02232
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1201
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83075
Perturb_523_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.77114
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62971
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mepenzolate bromide-2169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle lumen	GO Cellular Component Annotations 2023	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	5.28812
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836987
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0507
bepridil-4613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30633507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93543
SARS-CoV MA15_Day4_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9678
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.980211
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88158
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21674
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38375
adrenocortical carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60303
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7825
BRD-K07020302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13031
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XE-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.39322
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.5326
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975782
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.944
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6597
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K18768055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53231
polymorphism	GeneRIF Biological Term Annotations	1.0	null
membrane region	GO Cellular Component Annotations 2015	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849074
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64712
retinoic acid catabolic process	GO Biological Process Annotations 2023	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20299
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23331
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0621
lovastatin-2494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
cell surface	GO Cellular Component Annotations 2015	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930279
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32524
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
MFSD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72117
adrenal	GeneRIF Biological Term Annotations	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.19265
BRD-K33448511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11723
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleotide	GeneRIF Biological Term Annotations	1.0	null
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4737
heme binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29628
all-trans-retinol binding	GO Molecular Function Annotations 2025	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.4036
vancomycin-4423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49981
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13613
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16782
retinoic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
PMC12008806-mmc13.xlsx-ST12-Unnamed_37_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC11948025-ADVS-12-2416484-s001.pdf-118-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
BRD-K30121969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15881
BRD-K00907050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00605
Adrenal adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80859
LN382	CCLE Cell Line Gene Expression Profiles	1.0	1.36472
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49042040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00111
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06515
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828058
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58249
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.581
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32367
CRCGN017_MCF10A.TP53.M_24H:C06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06996
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19298
BL3720 (KDM4B)	NURSA Protein Complexes	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928554
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0577
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51731
organelle lumen	GO Cellular Component Annotations 2015	1.0	null
Duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0048
BRD-K44236678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11439
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.21369
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47539
variant	GeneRIF Biological Term Annotations	1.0	null
catalytically	GeneRIF Biological Term Annotations	1.0	null
BRD-K16207499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76765
Perturb_13776_KD_IFNAR2_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.10163
EWSR1_KD_GDS4962_466_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Hyperglycemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
T24	BioGPS Cell Line Gene Expression Profiles	1.0	1.16637
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.51021
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP5d	GDSC Cell Line Gene Expression Profiles	1.0	2.37858
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K21201014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2078
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19129
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.1428
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75842
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56598
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840181
Xenobiotics	Reactome Pathways 2024	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	0.960804
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20451
CORL23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34149
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43993
BRD-K73658839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2021
CRCGN015_MCF10A.TP53.M_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2599
Perturb_11426_KD_PRMT1_SRP357238	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.98402
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002594
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.905396
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055224
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55928
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	5.78129
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01449
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853008
Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)	Reactome Pathways 2014	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26874
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984352
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865542
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33236
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80057
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.802385
BRD-K20560768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31816
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867885
BRD-K72894736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26395
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0731
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089663
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26863838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23423
current	GeneRIF Biological Term Annotations	1.0	null
alleles	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994109
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.3714
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835338
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962588
HCC364	CCLE Cell Line Gene Expression Profiles	1.0	1.439
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
LS513	DepMap CRISPR Gene Dependency	1.0	2.01714
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Learning Disorders	CTD Gene-Disease Associations	1.0	1.04721
Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)	Reactome Pathways 2014	1.0	null
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81689
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11855
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9816
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084154
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.807716
Perturb_2120_KD_DDX5_SRP276651	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.48054
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53637
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14492
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895884
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2184
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydralazine-3724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-N87 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15734
Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77181307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02172
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55693
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K23628938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02015
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
adrenal cortex cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.563723
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68712
BRD-K24453679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89729
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6028
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.07625
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166319
H2722	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039291
HS852T	DepMap CRISPR Gene Dependency	1.0	2.26595
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
BRD-K68160857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67664
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886268
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07704
BRD-K66580188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39396
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051134
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70529
cellular ketone metabolic process	GO Biological Process Annotations 2015	1.0	null
Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)	Reactome Pathways 2014	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886268
nialamide-4525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31277
econazole-6008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56583
FOXD4L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30813
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066667
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82818
JHOM1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.00684
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33159
prognostic	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
doxorubicin-4610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estriol-6140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05918
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071131
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.83031
NELFE	ENCODE Transcription Factor Targets	1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01792
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909016
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05828
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05715
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993319
BRD-A24436948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09102
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939891
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
HuCCT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
significant	GeneRIF Biological Term Annotations	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30106
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-668	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94495
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48138
retinoic acid 4-hydroxylase activity	GO Molecular Function Annotations 2025	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19117
JHH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95107
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30833
mRNA_DPPA5A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23454
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.73984
EZH2	ChEA Transcription Factor Targets	1.0	null
BRD-K85532500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06721
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81426
zoxazolamine-2625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72060858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37934
BRD-K10705624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0783
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960815
POS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.1997
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9265
CRCGN010_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23885
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K26576471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35815
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.1401
trichostatin A-6171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49088
retinoic acid binding	GO Molecular Function Annotations 2025	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole	CTD Gene-Chemical Interactions	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
ZBTB26	Pathway Commons Protein-Protein Interactions	1.0	null
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
CRCGN017_MCF10A.TP53.M_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28434
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939891
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86497
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.09047
Perturb_3797_KO_BRG1_SRP165661	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33452
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
BRD-K73681382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21623
epirizole-5995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
retinoic acid binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K72800151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12629
interact	GeneRIF Biological Term Annotations	1.0	null
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)	Reactome Pathways 2014	1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.35929
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endoplasmic reticulum lumen	GO Cellular Component Annotations 2023	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00896
PMC7479515-mmc4.xlsx-ST-RELA-variable-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854144
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66462
Perturb_1080_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.08
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873808
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38419
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51821
BRD-K51237617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11933
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
link	GeneRIF Biological Term Annotations	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL14	CCLE Cell Line Gene Expression Profiles	1.0	2.05949
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29123
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68491
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41016
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11312
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952981
hsa-miR-4725-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052259
solasodine-3924	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10652
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0374
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17918
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936578
BXPC3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29465
Cytochrome P450, E-class, group I	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
diphenhydramine-6020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936301
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19618
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843612
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7797
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0973
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36249
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02798
BRD-K80819226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37566
canrenoic acid-6783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
halofantrine-6509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239436,GSE239441_0_v_1_keap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850017
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5335
TBP	ENCODE Transcription Factor Targets	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2822
intracellular organelle lumen	GO Cellular Component Annotations 2015	1.0	null
BL4071 (ILKAP)	NURSA Protein Complexes	1.0	null
BRD-K82791632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3917
sirolimus-6201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930767
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873835
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44222
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00833
BRD-K61912055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53131
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SNU1041	DepMap CRISPR Gene Dependency	1.0	9.87682
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.996765
CRCGN014_HEPG2_3H:D12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1593
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.70696
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956377
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899835
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
melatonin-2431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00503
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32703
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946785
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22584556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59257
monocarboxylic acid catabolic process	GO Biological Process Annotations 2023	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
carbamazepine-5518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40971
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
cytotoxic	GeneRIF Biological Term Annotations	1.0	null
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4132
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442194
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41149
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34518
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887899
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84843
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25423
hsa-miR-3147	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34685
serve	GeneRIF Biological Term Annotations	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38492
transformation	GeneRIF Biological Term Annotations	1.0	null
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28376
diphenylpyraline-2205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cyclopentolate-6132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887899
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCILY19	DepMap CRISPR Gene Dependency	1.0	3.02713
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.426
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17763
JHESOAD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17033
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78888
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03224
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10501
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31382
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NIX_Deficiency_GDS2630_160_mouse_spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
MM1S	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24159
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	5.75177
HT55	GDSC Cell Line Gene Expression Profiles	1.0	2.15731
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11066
HSF1_KD_GDS1733_757_human_HeLa cells - 4 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.25373
Disease	Reactome Pathways 2014	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064898
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K45642123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30057
SNU-387	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08875
Perturb_2466_KD_NDP52_SRP345458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.33518
CRCGN015_MCF10A.TP53.M_24H:C13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87235
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7817
phospholipid metabolic process	GO Biological Process Annotations 2023	1.0	null
GSU	DepMap CRISPR Gene Dependency	1.0	5.74105
BRD-K57734337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19006
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29382
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871166
pilocarpine-3300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
DLD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01735
marker	GeneRIF Biological Term Annotations	1.0	null
HEYA8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93894
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03073
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
TE6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53218
BRD-K74927219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29372
nifurtimox-7328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24732
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937486
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854025
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26779
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59917
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
selective	GeneRIF Biological Term Annotations	1.0	null
BRD-K74289419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71498
BRD-K34489277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69983
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04223
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2691
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66699
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1026
lysophospholipids	GeneRIF Biological Term Annotations	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16838
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193351_4_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37571
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53056
PMC10534007-Table_2.xlsx-S4_unique_down_MSC_V-745_elements_included_exclusively_in_VM-CUB1_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.37143
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67324
BRD-K24719325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81647
BL4731 (ATXN2)	NURSA Protein Complexes	1.0	null
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04603
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03001
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06
controls	GeneRIF Biological Term Annotations	1.0	null
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68241
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62136
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40744
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hepa-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
mRNA_FEM1B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451428
EZH2	ENCODE Transcription Factor Targets	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27859
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40681
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MTHFD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69258
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0644
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48255
rat	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90504
EPI-1618-1 (TEC)	NURSA Protein Complexes	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heliotrine-3717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957359
previous	GeneRIF Biological Term Annotations	1.0	null
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43278
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854025
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.47226
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW579	CCLE Cell Line Gene CNV Profiles	1.0	2.69107
BRD-K21059010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61643
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09213
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.4832
retinoic acid 4-hydroxylase activity	GO Molecular Function Annotations 2023	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33602
endoplasmic reticulum part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881132
BRD-K80564983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09156
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58958
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37171
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
suggesting	GeneRIF Biological Term Annotations	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.71343
catabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00412
BL2603 (MED24)	NURSA Protein Complexes	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0511
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954165
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51614
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9761
BRD-K20065789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12774
Perturb_7867_KD_RNaseH2A_SRP252761	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.41556
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40779
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
CP-320650-01-4379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4028
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.65722
rotenone-5920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5309
CALU1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19168
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31803
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59681
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926854
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20661
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.051
endoplasmic reticulum part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.354042
tilorone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1277
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933327
BRD-K04757670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0356
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75406
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15298
mycotoxin metabolic process	GO Biological Process Annotations 2025	1.0	null
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16836
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16875
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23418
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.95429
BRD-K13122526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21602
PC-14	GDSC Cell Line Gene Expression Profiles	1.0	1.64202
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.4886
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28177
BRD-K00698280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48505
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.68662
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45381
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-4J-AA1J-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83871
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09135
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3541
hydrastine hydrochloride-6011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25451
hymecromone-3045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nuclear aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04138
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64107
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03859
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59836
phospholipid metabolic process	GO Biological Process Annotations 2025	1.0	null
BL6415 (BCR)	NURSA Protein Complexes	1.0	null
nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.566
Prestwick-984-4948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5458
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4-hydroxyphenazone-4095	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48086
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.41979
Interrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29182
CRCGN015_MCF10A_48H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07123
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8218
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0722
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Lung-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	2.39158
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.97667
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-A02612852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35699
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.094
caucasian	GeneRIF Biological Term Annotations	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16012
higher	GeneRIF Biological Term Annotations	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54729
Insomnia symptoms (never/rarely vs. sometimes/usually)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32185
Perturb_1078_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
BRD-K63579322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34713
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976299
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26423
RBPJ	ChEA Transcription Factor Targets	1.0	null
Ski complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94471
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837557
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19669
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081052
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33628
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22082
secondary metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959683
BRD-K31602464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49319
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
sisomicin-2493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adrenal cortical adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
tumorspecific	GeneRIF Biological Term Annotations	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24892
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903542
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74707
HUH1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56669
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27408
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45628
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04773
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36588
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4730-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5113
NB10	DepMap CRISPR Gene Dependency	1.0	5.84627
OVCA-432 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8956
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.758631
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896637
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8812
SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.0353
COLO704	CCLE Cell Line Gene Expression Profiles	-1.0	-2.71589
COR-L105	GDSC Cell Line Gene Expression Profiles	1.0	1.42716
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0581
did	GeneRIF Biological Term Annotations	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.9968
mycotoxin metabolic process	GO Biological Process Annotations 2015	1.0	null
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.80206
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39885
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22669
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872727
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64272
Perturb_407_OE_DPP4_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066065
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26821
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24214
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
BRD-K07825644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50471
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22865
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78818514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04709
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5543
fat-soluble vitamin catabolic process	GO Biological Process Annotations 2023	1.0	null
BRD-K83562499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13834
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14353
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
lincomycin-5992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Miscellaneous substrates	Reactome Pathways 2014	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11312
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91047
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908