association	dataset	threshold value	standardized value
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.78743
Autosomal recessive congenital ichthyosis 5	ClinVar Gene-Phenotype Associations	1.0	null
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12206
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06254
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
palmoplantar keratoderma	HPO Gene-Disease Associations	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
abnormality of bone marrow cell morphology	HPO Gene-Disease Associations	1.0	null
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	5.04039
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4185
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2754
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1290_KO_Lef1_SRP111197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.80855
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040494
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.21753
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72764
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537731
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55746
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03341
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92766
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.79997
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850458
hsa-miR-135a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38132
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34009
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sphingolipid biosynthetic process	GO Biological Process Annotations 2023	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834893
HDAC2	ENCODE Transcription Factor Targets	1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26567
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27954
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06931
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
Perturb_5017_KD_Dppa2_SRP187465	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.34936
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.34
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09882
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45034
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969705
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056206
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872609
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18803
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841732
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.107665
Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)	Reactome Pathways 2014	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW579	CCLE Cell Line Gene CNV Profiles	1.0	1.73833
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lamellar	GeneRIF Biological Term Annotations	1.0	null
neurofibromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266558
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04618
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120492
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.8704
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703127
LUF-5735	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
Thyroid cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08578
Fatty acids	Reactome Pathways 2024	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056022
TDOTT	DepMap CRISPR Gene Dependency	1.0	3.55332
Peeling skin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
A673	CCLE Cell Line Gene Expression Profiles	1.0	2.52648
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64259
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.92529
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
Perturb_13099_OE_Dux_SRP220068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.16921
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.88088
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51519
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6349
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.387
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70882
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85166
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974888
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07555
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.23251
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041218
DIFI	DepMap CRISPR Gene Dependency	1.0	2.10219
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07033
20-Hydroxy-leukotriene B4	HMDB Metabolites of Enzymes	1.0	null
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.62657
KMRC20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63008
Perturb_12222_KD_FOXA1_SRP267080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08943
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16817
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53206
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254902
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80647
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929918
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2968
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94484
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1183
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045984
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85563
ichthyosis, congenital, autosomal recessive 5	OMIM Gene-Disease Associations	1.0	null
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03253
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02242
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49555
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46006
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07078
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56102
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897042
abnormality of lower lip	HPO Gene-Disease Associations	1.0	null
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0635
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11486
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34105
ichthyosis	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993749
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27483
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980218
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.327
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_baboon_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
CAMA1	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17171
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41703
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
PAX6	ChEA Transcription Factor Targets	1.0	null
GSE231339_1_v_0_itgav_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9224
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8363
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)	Reactome Pathways 2014	1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
Chloroplast nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834447
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11352
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	5.82691
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.72376
Li	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.694
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GW7647	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82023
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92813
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435672
DG-75 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
impaired skin barrier function	MGI Mouse Phenotype Associations 2023	1.0	null
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1229
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.77836
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55401
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
inflammatory abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Chloroplastic endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.642
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nfe2l2_2383093_whole_skin_gof_mouse_gpl1261_gse35160	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.533639
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_4_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863825
Rucinol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.21
binding	GO Molecular Function Annotations 2015	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27885
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04263
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85726
Keratosis pilaris atrophicans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.044991
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Photosensitive trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
CH157MN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14901
Perturb_14241_KO_Tet1_SRP237910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.93265
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11175
KYSE270	CCLE Cell Line Gene Expression Profiles	1.0	1.55197
NCIN87	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17798
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51014
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25065
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131783
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51188
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938335
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95428
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29457
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21985
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ewing's sarcoma family tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.43517
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38959
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MFE280	DepMap CRISPR Gene Dependency	1.0	5.81501
Metabolism of lipids	Reactome Pathways 2024	1.0	null
quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48245
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17691
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26693
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.943499
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.97268
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.090235
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A89H-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210203
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.0744
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
HS863T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63591
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29514
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062814
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36647
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04193
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.190113
BT483	CCLE Cell Line Gene Expression Profiles	1.0	1.63896
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.459
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
19286929-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.07916
Chloro-L-alanine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
Fatty acids	Reactome Pathways 2014	1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18549
dystrophy	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02955
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07794
dehydration	HPO Gene-Disease Associations	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062407
c211	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.935
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.122
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heme binding	GO Molecular Function Annotations 2015	1.0	null
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Reactome Pathways 2014	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.262
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25145
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94079
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC298	CCLE Cell Line Gene CNV Profiles	1.0	1.70985
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_193_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.00493
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
PMC12882559-12894_2026_2046_MOESM2_ESM.docx-0-ZNF770_ZNF770	Rummagene Transcription Factor Associations 2026	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7817
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_12-Supplementary_Table_12_ETV6-activated_genes_defined_by_dTAG_at_6_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07877
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21902
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.90628
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874183
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6451
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65207
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08102
Acanthosis	DisGeNET Gene-Phenotype Associations	1.0	null
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907189
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18111
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.514924
DNA recombinase mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
NCIH2122	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32325
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18841
RCM1	DepMap CRISPR Gene Dependency	1.0	5.18582
Perturb_5436_KO_Rspo3_SRP363653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.87675
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851574
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.96778
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909013
PMC4387713-supp_gad.255984.114_Table_S3.xlsx-S3A-Down_Dpy30_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.10734
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74824
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO792	DepMap CRISPR Gene Dependency	1.0	2.06909
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852775
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.5386
TC32	CCLE Cell Line Gene Expression Profiles	1.0	2.35336
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6843
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905829
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74771
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25665
Dry Skin, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436822
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995046
breast carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.349349
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055651
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878074
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081128
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
NCIH2172	CCLE Cell Line Gene Expression Profiles	1.0	1.38423
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LinE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_14-Supplementary_Table_14_ETV6-activated_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7488
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122222
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TT	CCLE Cell Line Gene Expression Profiles	1.0	1.59158
LN443	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29435
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
MCF7	DepMap CRISPR Gene Dependency	1.0	4.25515
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47678
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1264
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12984
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.32297
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27394
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18038
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04158
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0636
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13144
HEY	DepMap CRISPR Gene Dependency	1.0	2.06569
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-Veh_KO_vs_WT-Supplementary_Table_S2-1_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_Vehicle_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00591
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02537
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)	Reactome Pathways 2014	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32333
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20784
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02317
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24237
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2122 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
Miscellaneous substrates	Reactome Pathways 2024	1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18665
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49216
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sulcotrione	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective FMO3 causes Trimethylaminuria (TMAU)	Reactome Pathways 2014	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17555
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826782
GSE156923_0_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48665
everted lower lip vermilion	HPO Gene-Disease Associations	1.0	null
corneoretinal	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23653
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09341
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB468	DepMap CRISPR Gene Dependency	1.0	2.09097
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051618
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23006
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21169
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61203
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24168
Familial woolly hair syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Congenital Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_12842_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.12095
Sparse Hair	DisGeNET Gene-Phenotype Associations	1.0	null
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060948
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03213
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048389
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
Eversion Of Lower Lip	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22271
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842303
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_218_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09673
Louping ill	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biettis	GeneRIF Biological Term Annotations	1.0	null
Water	HMDB Metabolites of Enzymes	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.290994
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15533
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28177
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.59966
ceramide metabolic process	GO Biological Process Annotations 2023	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
fatty acid derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921578
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.40288
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47984
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25425
Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)	Reactome Pathways 2014	1.0	null
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19507
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17985
lack of skin elasticity	HPO Gene-Disease Associations	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057739
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8734
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979374
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bietti crystalline corneoretinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
Somatodendritic compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.949
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.248339
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438356
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60058
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71125
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848599
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3491
Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)	Reactome Pathways 2014	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64259
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12034
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1916
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64259
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39706
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91196
Perturb_10228_KO_Nfat5_SRP337224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.95773
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
bleomycin_mus musculus_gpl1261_gse25640	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thickened skin	HPO Gene-Disease Associations	1.0	null
extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721166
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1808
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.72
OELE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2992
Prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59523
Blepharitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
NCI-H1155 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.3462
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.01437
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40589
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01187
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.276
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.40883
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27536
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
KYSE140	DepMap CRISPR Gene Dependency	1.0	2.00631
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.644593
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36972
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8069
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5165
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12404
highly	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5259
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05908
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFE184	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37304
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859699
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acenaphthoquinone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02839
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07723
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04747
PPARG	ChEA Transcription Factor Targets	1.0	null
Oxidation by Cytochrome P450(Mus musculus)	WikiPathways Pathways 2014	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08253
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078909
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937868
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120492
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0328
Holocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07268
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.94185
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38573
LC1SQSF	CCLE Cell Line Gene Expression Profiles	1.0	1.46649
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20923
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08389
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.853629
Eicosanoids	Reactome Pathways 2014	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12721
collodion	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07665
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.765127
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825107
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6307
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43209
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02333
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-512-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF440	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33234
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
BT20	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.36348
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.913899
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
chr19_15507960_T_C_b38	GTEx eQTL 2025	1.0	1.37355
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00616
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886658
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51596
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35092
NADP	HMDB Metabolites of Enzymes	1.0	null
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Reactome Pathways 2024	1.0	null
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.197993
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02445
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181798
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17257
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60535
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Keratosis follicularis spinulosa decalvans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050935
Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.47186
Parotid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0379
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78315
ARC syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Perturb_14934_KO_Ythdf2_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.14437
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850228
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_177_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-1626-SM-4BONV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891978
Autosomal recessive congenital ichthyosis 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.739
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863571
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.45388
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5479
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMOTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01355
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10175786-Table4.XLSX-Sheet_1-GSE7410_AND_GSE63514_NOT_GSE9750_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62576
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22678
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NO11	DepMap CRISPR Gene Dependency	1.0	6.70694
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990751
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838907
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MERO25	DepMap CRISPR Gene Dependency	1.0	2.28247
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960631
HCT15	DepMap CRISPR Gene Dependency	1.0	2.10831
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02101
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01317
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76037
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14684_KO_Prkaa1/Prkaa2_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.92228
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
abnormality of fluid regulation	HPO Gene-Disease Associations	1.0	null
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61221
ZNF263	ENCODE Transcription Factor Targets	1.0	null
xenobiotic metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911879
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00265
TIS granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20999
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48514
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.327
Epidermal lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21292
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00157
Autosomal recessive congenital ichthyosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
c92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.015
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05321
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72765
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.9542
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18184
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27289
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85294
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42716
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.514
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exfoliative Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10016
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	0.933106
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01051
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55883
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01424
glial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10006
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03272
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8245
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824422
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.81163
hsa-miR-3180-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07441
Crouzon syndrome-acanthosis nigricans syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05261
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884819
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01559
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Phase 1 - Functionalization of compounds	Reactome Pathways 2014	1.0	null
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088238
LOMEGUATRIB	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
ZNF622_02_108	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.02975
Dehydration	DisGeNET Gene-Phenotype Associations	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69329
Spastic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9902
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82495
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13112
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24147
membrane region	GO Cellular Component Annotations 2015	1.0	null
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
baby	GeneRIF Biological Term Annotations	1.0	null
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
GDM1	CCLE Cell Line Gene Expression Profiles	1.0	1.75451
brain	HPA Tissue Gene Expression Profiles	-1.0	-0.856575
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84147
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32963
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GATA2	ChEA Transcription Factor Targets	1.0	null
NADPH	HMDB Metabolites of Enzymes	1.0	null
abnormal epidermis stratum corneum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Defective MAOA causes Brunner syndrome (BRUNS)	Reactome Pathways 2014	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
AS-605240	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32661
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Metabolism	Reactome Pathways 2014	1.0	null
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07555
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4636
Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32416
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
sphingolipid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.381
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54063
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4327
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
wrinkled skin	MGI Mouse Phenotype Associations 2023	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37523
mode of inheritance	HPO Gene-Disease Associations	1.0	null
carboxylic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.8453
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04301
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13481
cii3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01529
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63529
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059753
crystalline	GeneRIF Biological Term Annotations	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935358
3-Benzyloxyaniline	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.65
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91021
hsa-miR-2964a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Oxidation by cytochrome P450	WikiPathways Pathways 2024	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057725
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21753
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24237
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43229
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046089
GSE213410_0_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH322	DepMap CRISPR Gene Dependency	1.0	2.27188
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.072366
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70843
SHMAC5	DepMap CRISPR Gene Dependency	1.0	5.4199
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40519
abnormality of the lip	HPO Gene-Disease Associations	1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
onset	GeneRIF Biological Term Annotations	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937868
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20185
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072534
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055791
been	GeneRIF Biological Term Annotations	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840449
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4315
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exposure keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08124
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0458
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0417
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_13-Supplementary_Table_13_ETV6-activated_genes_defined_by_dTAG_at_24_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041769
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05056
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
SKNMC	CCLE Cell Line Gene Expression Profiles	1.0	1.71342
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33628
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23469
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.41
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24118
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	164.444
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
PMC9332298__F2	PFOCR Pathway Figure Associations 2024	1.0	null
placenta	HPA Tissue Gene Expression Profiles	-1.0	-0.856575
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13952
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7141
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU1196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36398
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EZH2	ENCODE Transcription Factor Targets	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.24947
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09552
Ichthyosiform Erythroderma, Congenital	DisGeNET Gene-Disease Associations	1.0	null
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882358
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55916
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1049
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0813
astrocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129841
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48659
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987833
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6086
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09436
long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290652
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00719
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86714
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52638
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.285671
Vibrissal follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902095
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869564
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36677
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.67
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.32345
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00854
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880716
PMC10274772-media-2.xlsx-TFAP2A_motif_in_promoters-TFAP2A_target_genes_with_TFAP2A_motif_in_their_promoter_region_n_64_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829368
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ceramide biosynthetic process	GO Biological Process Annotations 2025	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tetrapyrrole binding	GO Molecular Function Annotations 2015	1.0	null
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MG-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT4_KD_GDS1824_135_mouse_embryonic stem (ES)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Aplasia/Hypoplasia Of The Eyebrow	DisGeNET Gene-Phenotype Associations	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
KU-60019	DeepCoverMOA Drug Mechanisms of Action	1.0	0.63
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56182
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4191
Thoracic spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
MF63	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reddish skin	MGI Mouse Phenotype Associations 2023	1.0	null
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.23902
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06254
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062079
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34717
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8363
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936872
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
bp86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.47931
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986635
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.646
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
AK-54059	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825438
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02566
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14481
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.04
Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)	Reactome Pathways 2014	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35841
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42398
protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.96809
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045954
prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445653
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
brain cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127826
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57745
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74171
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4682	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOV21G	Achilles Cell Line Gene Essentiality Profiles	1.0	1.79644
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878968
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Dry Skin	DisGeNET Gene-Phenotype Associations	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.34028
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98335
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11079
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0625
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.83462
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907564
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	4.70033
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.31992
GSS	DepMap CRISPR Gene Dependency	1.0	2.68764
analyses	GeneRIF Biological Term Annotations	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43724
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616183
abnormality of body height	HPO Gene-Disease Associations	1.0	null
Nrf2_deficiency_GDS3406_156_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993336
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNP-470	DeepCoverMOA Drug Mechanisms of Action	1.0	0.72
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3997
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.461
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08102
Lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.172
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16869
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51524
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056725
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994356
U87MG	DepMap CRISPR Gene Dependency	1.0	2.7298
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
decreased ceramide level	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	249.161
Hemangioma of liver	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.049
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
skin	GeneRIF Biological Term Annotations	1.0	null
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.683493
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)	Reactome Pathways 2014	1.0	null
Perindopril	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14504
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449947
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10641
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49107
HNF4A	ChEA Transcription Factor Targets	1.0	null
hsa-miR-135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22602
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.93483
cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.731442
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06254
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.67553
Oxygen	HMDB Metabolites of Enzymes	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44888
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal recessive congenital ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SMAD5_02_48	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
Epidermolytic hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.191
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10343
abnormality of the helix	HPO Gene-Disease Associations	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
japanese	GeneRIF Biological Term Annotations	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleosome disassembly/reassembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Defective CYP4F22 causes ARCI5	Reactome Pathways 2024	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9856
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
EGR1	ENCODE Transcription Factor Targets	1.0	null
amide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1908
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945605
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15011_KO_Eed/Xist_SRP365240	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.48233
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88212
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.58284
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
renal insufficiency	HPO Gene-Disease Associations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870328
la4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40519
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50927
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056725
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04706
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933299
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3200-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	2.5691
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26124
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07647
MITF	ChEA Transcription Factor Targets	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08954
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29688
Icthyosis	DisGeNET Gene-Disease Associations	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23961
growth delay	HPO Gene-Disease Associations	1.0	null
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.652484
lb7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28878
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842608
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41972
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27677
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.228
CHILD syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
Autosomal recessive Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3495
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72894
Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)	Reactome Pathways 2014	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Autosomal recessive congenital ichthyosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
ceramide metabolic process	GO Biological Process Annotations 2025	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83818
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Regular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
Typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
thecyp4f22	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1893
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31609
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05397
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85879
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290652
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-3202	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Ainhum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
DU145	CCLE Cell Line Gene Expression Profiles	-1.0	-2.54844
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42092
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38443
Perturb_2605_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.39048
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12721
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ctv1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82628
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1257
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TWIST1_01_252	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59359
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04221
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43291
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9173
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
cyp4v2gene	GeneRIF Biological Term Annotations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159324
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
short stature	HPO Gene-Disease Associations	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908406
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)	Reactome Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59122
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12857
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992416
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13283
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06157
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02065
icosanoid metabolic process	GO Biological Process Annotations 2025	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytochrome P450 - arranged by substrate type	Reactome Pathways 2024	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6358_KO_NumbL_SRP307901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.86237
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7975
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05909
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57402
20-Hydroxyeicosatetraenoic acid	HMDB Metabolites of Enzymes	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
suffering	GeneRIF Biological Term Annotations	1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3275
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.675571
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.42257
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.993581
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.139
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
linked	GeneRIF Biological Term Annotations	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19537
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22078
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57458
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MARCKSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21782
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846718
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73057
OCIAML5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17611
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5897
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436055
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230656
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47573
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051842
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.834013
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	2.14185
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.70272
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9152
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	2.2702
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159124
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25373
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.31029
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4709
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49597
bmmc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
Autosomal dominant sensory ataxia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35092
all	GWASdb SNP-Phenotype Associations	1.0	0.028197
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67396
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1667
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33818
Cicatricial ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832161
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6024232__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61124
Disease	Reactome Pathways 2014	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)	Reactome Pathways 2014	1.0	null
abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.932337
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22231
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29469
7-Hydroxycoumarine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53575
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10435
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12253
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888529
Fatty acid metabolism	Reactome Pathways 2024	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.701928
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097364
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49216
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852566
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8001
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66503
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
EPI-2298-1 (BRAF)	NURSA Protein Complexes	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936872
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.57502
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1797
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.297
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09552
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95385
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4555
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10227
GSE223008_7_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
Autosomal recessive congenital ichthyosis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.131
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5517
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.771
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
wf2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STX-0119	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32064
TP53INP2_OE_GDS5054_545_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
epidermal thickening	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973078
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877466
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.53173
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
Dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.966
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84782
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PK1	DepMap CRISPR Gene Dependency	1.0	2.46925
poikilocytosis	HPO Gene-Disease Associations	1.0	null
Recurrent corneal erosion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043713
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56031
a95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18665
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21498
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17344
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.791
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12077
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10172
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.547807
Leukotriene B4	HMDB Metabolites of Enzymes	1.0	null
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.81904
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06153
Scrub typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71331
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.23251
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital ichthyosiform erythroderma	ClinVar Gene-Phenotype Associations 2025	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03136
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22448
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.45019
HSF1_02_73	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61727
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34665
dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.321575
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11857
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166167
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6144
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937868
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4949
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nonepidermolytic palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20747
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05741
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045776
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208245
ceramide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12789
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.263
ML218	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54474
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.715618
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15441
liver	HPA Tissue Gene Expression Profiles	1.0	0.919465
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870328
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20784
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94652
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856317
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27736
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3109859__F6	PFOCR Pathway Figure Associations 2024	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.173804
RGFP966	DeepCoverMOA Drug Mechanisms of Action	1.0	0.78
NCIH727	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73154
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50886
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27674
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carboxylic acid metabolic process	GO Biological Process Annotations 2023	1.0	null
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84079
report	GeneRIF Biological Term Annotations	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.72872
HN	CCLE Cell Line Gene CNV Profiles	1.0	2.08829
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13078
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55242
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
astrocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141036
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.07966
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1593
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02378
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01249
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSD17B4_KO_GDS3468_503_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
rectum_8d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.617393
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
acanthocytosis	HPO Gene-Disease Associations	1.0	null
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59925
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69591
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25355
TE10	DepMap CRISPR Gene Dependency	1.0	4.23088
Oxidation by Cytochrome P450(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39162
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30238
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895303
NALM6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.3408
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
SREBF1	ChEA Transcription Factor Targets	1.0	null
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89486
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01935
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27802
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Perturb_2587_KD_NUDT3_SRP066365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.1789
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ductal carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353763
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45267
Pachyonychia congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
weight loss	MGI Mouse Phenotype Associations 2023	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16291
needle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.733089
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294939
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30628
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
UBE2L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68787
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0395
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3783
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10991
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32872
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97952
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00265
TP53	ChEA Transcription Factor Targets	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2423
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02445
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
parakeratosis	HPO Gene-Disease Associations	1.0	null
cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.489731
abnormal hair quantity	HPO Gene-Disease Associations	1.0	null
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00653
Rosiglitazone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Juvenile leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1145
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073172
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05923
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08295
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25315
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00104
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51547
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27009
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.65914
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09732
Biological oxidations	Reactome Pathways 2014	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SKN	DepMap CRISPR Gene Dependency	1.0	2.45955
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
496100403_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09903
spectrum	GeneRIF Biological Term Annotations	1.0	null
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25425
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.31791
GTEX-XUW1-0326-SM-4BOOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849725
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17418_KO_Myd88_ERP115704	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11313
Shu complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50761
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	2.09647
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37763
GSE157233_1_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
shiny skin	MGI Mouse Phenotype Associations 2023	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_550_KD_EWSR1FLI1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.4828
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.524
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043373
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.54242
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921256
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063146
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33081
Netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.26
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17038
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
description	GeneRIF Biological Term Annotations	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
hsa-miR-3196	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960162
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1323
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.16846
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	1.38192
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40448
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18184
SYO1	DepMap CRISPR Gene Dependency	1.0	2.71485
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91708
BBLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85485
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59001
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0499
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.63472
tRNA (m1A) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.194
NUSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80935
TE-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900713
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19031
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.35899
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06828
PMC8578301__F1	PFOCR Pathway Figure Associations 2024	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8755
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01618
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931336
COLO704	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21696
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10015
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0327
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52851
eclabion	HPO Gene-Disease Associations	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060456
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22775
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00014
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20637
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69333
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7254
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51397
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21396
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
hsa-miR-4260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56031
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1804
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9724
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87657
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82808
PMC5595433-elife-27450-supp1.xlsx-Figure_2_Gene_Lists-BOM_Upregulated_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38659
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2307
u	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.55
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15209
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.36491
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21692
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.139341
recurrent infections	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.8877
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20784
DMS-114	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.34564
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264011
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.362
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33785
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922184
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19558
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Lung squamous cell carcinoma_LUSC_TCGA-68-7755-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937868
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06467
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.483421
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14836
Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.2873
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
8MGBA	DepMap CRISPR Gene Dependency	1.0	2.8352
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72501
Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3160-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7045
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
ml86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
histamine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	2.81986
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Leaf bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Chanarin-Dorfman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.152533
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02739
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31119
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09436
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044274
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853834
tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454898
PMC12508431-44319_2025_552_MOESM1_ESM.xlsx-Table_EV1-Table_EV1_EWS_FLI1_sensitive_gene_targets_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840707
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24381
HY-50713	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TC-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06254
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Sjogren-Larsson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45315
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33572
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
lm8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333396
metabolic process	GO Biological Process Annotations 2015	1.0	null
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00048
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.872606
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064481
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665588
Mildronate	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
Metabolism of lipids and lipoproteins	Reactome Pathways 2014	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
Eicosanoids	Reactome Pathways 2024	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
Arachidonate metabolism	Reactome Pathways 2024	1.0	null
Chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35116
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51188
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19905
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40243
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25443
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.861508
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.467
Dendritic tree	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.965
PMC9374162-mmc3.xls-126_gene_details_MSC_EF_EWSZF7-Gene_name_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97858
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0721
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39778
Congenital Nonbullous Ichthyosiform Erythroderma	DisGeNET Gene-Disease Associations	1.0	null
arthrogryposis, renal dysfunction, and cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
KLF4	ChEA Transcription Factor Targets	1.0	null
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01562
abnormal corneocyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937868
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13519
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	2.62282
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-381-RFX1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
pre-malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280082
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05906
Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)	Reactome Pathways 2014	1.0	null
glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.48853
abnormal periderm morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07471
wide	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3862
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.93097
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20828
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.238
Perturb_15188_KD_BRG1/BRM_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
Preputial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58248
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.386
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
cognitive impairment	HPO Gene-Disease Associations	1.0	null
Photosensitive trichothiodystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73425
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
PMC8326207__SF2	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40665
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997239
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02482
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0498
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40665
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18847
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
dry skin	HPO Gene-Disease Associations	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96451
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5451
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2884
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23744
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55275
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.649
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399871
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
iron ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948562
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29972
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1357
lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.534951
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_baboon_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.992507
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002
nucleotide-excision repair factor 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10883
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00392
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03782
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58624
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45431
Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)	Reactome Pathways 2014	1.0	null
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
Skull base chordoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03039
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83861
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytochrome P450, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NCIH838	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01542
Abnormality Of The Helix	DisGeNET Gene-Phenotype Associations	1.0	null
Biological oxidations	Reactome Pathways 2024	1.0	null
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	13.1778
otitis media	HPO Gene-Disease Associations	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20369
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870248
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07078
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4751	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908552
SKES1	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98959
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.799966
Autosomal recessive congenital ichthyosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78342
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hyperkeratosis	DisGeNET Gene-Phenotype Associations	1.0	null
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28787
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99605
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07411
Perturb_552_KD_EWSR1/EWSR1FLI1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RDES	CCLE Cell Line Gene Expression Profiles	1.0	2.44981
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.248339
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917075
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870328
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2971
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metapathway biotransformation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06254
Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)	Reactome Pathways 2014	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868769
Autosomal recessive congenital ichthyosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60706
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432225
spinal meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.50798
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965306
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.404
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68809
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13607
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.31741
Self-Healing Collodion Baby	DisGeNET Gene-Disease Associations	1.0	null
HOXD9_01_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59298
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25432
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
PMC12808183-41598_2025_31780_MOESM7_ESM.pdf-1-FOXN1_FOXN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31623
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78416
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.861752
GSE241875_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15396
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5895
bone marrow cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294939
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42691
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09301
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2861	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26327
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118827
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Eye-adipocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.488089
Methazolamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.19
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12844
Miscellaneous substrates	Reactome Pathways 2014	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14228
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
SKGII	DepMap CRISPR Gene Dependency	1.0	2.65082
spinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18971
Leber congenital amaurosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.059548
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
respiratory tract infection	HPO Gene-Disease Associations	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75004
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66473
U178	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.45833
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65427
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-744	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
Metabolism	Reactome Pathways 2024	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Anagrelide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10826
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56182
Cicatricial lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
Ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.867
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52386
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6024232__F2	PFOCR Pathway Figure Associations 2023	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.28179
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99002
Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)	Reactome Pathways 2014	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8279
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
FOXA1_01_104	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.43451
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.1537
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910126
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4119
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Median body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.26065
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43825
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079999
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54086
HKA1	DepMap CRISPR Gene Dependency	1.0	2.25879
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00446
CBX2	ENCODE Transcription Factor Targets	1.0	null
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Erep	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
SW480	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22125
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.78692
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05743
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
Abetalipoproteinemia	DisGeNET Gene-Disease Associations	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89091
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3491
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53INP2_OE_GDS5054_387_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of erythrocytes	HPO Gene-Disease Associations	1.0	null
PMC10274772-media-2.xlsx-TFAP2A_motif_in_enhancers-TFAP2A_target_genes_with_TFAP2A_motif_in_their_enhancer_region_n_99_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3817
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
letter	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831982
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46768
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
KARPAS422	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64514
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
PMC7880379-aging-13-202285-s003.xlsx-DElncRNA_target-FEZF1_FEZF1	Rummagene Transcription Factor Associations 2026	1.0	null
amide biosynthetic process	GO Biological Process Annotations 2025	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21088
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24237
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40665
BC3C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66042
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52244
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0786
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pruritus	HPO Gene-Disease Associations	1.0	null
hsa-miR-3180	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
ichthyosis	GeneRIF Biological Term Annotations	1.0	null
aplasia/hypoplasia of the eyebrow	HPO Gene-Disease Associations	1.0	null
Laryngeal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB453	Achilles Cell Line Gene Essentiality Profiles	1.0	1.70885
Nail Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06599
erythroderma	HPO Gene-Disease Associations	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12959
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061314
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04747
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08102
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36586
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04409
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5697
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870328
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
TAK-875	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-1.21753
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31394
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15943
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61142
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.50732
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.872
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSK4112	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
MSTO-211H	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.34405
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.0007
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266069
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
timing	GeneRIF Biological Term Annotations	1.0	null
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.181
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2024	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11965_KO_IRF4_SRP401628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07536
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01826
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03169
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
all	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MKN45	DepMap CRISPR Gene Dependency	1.0	3.40665
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4666
Lamellar ichthyosis, type 3	CTD Gene-Disease Associations	1.0	2.88009
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327896
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43368
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61648
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lasmiditan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.253
Moh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
PMC3109859__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_15712_KD_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.81582
LP1	DepMap CRISPR Gene Dependency	1.0	3.61428
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
MTMR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29463
SNU1079	DepMap CRISPR Gene Dependency	1.0	4.2028
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.18216
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
Cloprostenol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.62
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44552
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.417
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.42599
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
keratinization	GeneRIF Biological Term Annotations	1.0	null
NCIH1650	DepMap CRISPR Gene Dependency	1.0	5.58472
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr19_15508501_G_A_b38	GTEx eQTL 2025	1.0	1.88841
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26406
TE125T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.986
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09536
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
k22	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
abnormality of the nail	HPO Gene-Disease Associations	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61778
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19597
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55024
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.63207
site	GeneRIF Biological Term Annotations	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.567403
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
bp96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11085
icosanoid metabolic process	GO Biological Process Annotations 2023	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75619
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66298
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
Dapagliflozin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044866
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6591
congenital ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.00603
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormality Of The Dentition	DisGeNET Gene-Phenotype Associations	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cornified envelope formation	KEGG Pathways 2026	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17773
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228764
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28191
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0264
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70718
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	2.59975
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29187
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.35963
prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03009
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5309
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
recurrent respiratory infections	HPO Gene-Disease Associations	1.0	null
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58813
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
Heme	HMDB Metabolites of Enzymes	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.53349
XRCC2-RAD51D complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
jm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998735
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70394
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91464
skin	GTEx Tissue Gene Expression Profiles	1.0	1.03002
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080743
gangrene	HPO Gene-Disease Associations	1.0	null
Secretory trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.299
HT-144	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
ZSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72208
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89705
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.825
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25498
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15742
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08239
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059431
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75312
congenital ichthyosiform erythroderma	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82115
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14893
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53225
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
abnormal epidermal lamellar body morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Cytochrome P450	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45596
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063101
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430312
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15883
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5629
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09506
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47244
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03213
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02898
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01993
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.29698
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.90999
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.67173
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.557
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
NB-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMV-II cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Acrodysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0977
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
Parakeratosis	DisGeNET Gene-Disease Associations	1.0	null
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60156
Spastic quadriplegic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
DETROIT562	DepMap CRISPR Gene Dependency	1.0	2.06626
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cytochrome P450 - arranged by substrate type	Reactome Pathways 2014	1.0	null
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945454
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.098
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35326
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.09569
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TNIK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12203
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.4546
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14711
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Autosomal dominant Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10435
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16571
Cytochrome P450, E-class, group I	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875291
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24118
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56172
capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293151
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60477
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6466
c91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23699
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837836
Ectropion	DisGeNET Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8272
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928133
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939737
PL4	DepMap CRISPR Gene Dependency	1.0	2.79511
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart  (day 12.5 C57Bl/6)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Arachidonic acid metabolism	Reactome Pathways 2014	1.0	null
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
Perturb_15717_OE_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.0449
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53942
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glioblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146026
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53INP2_OE_GDS5054_385_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489447
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gamg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17136
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
SK-ES-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.27921
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20112
Disease	Reactome Pathways 2024	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
monooxygenase activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45V-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43514
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-3184	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5499
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1908	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54328
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of blood and blood-forming tissues	HPO Gene-Disease Associations	1.0	null
Autosomal recessive congenital ichthyosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.105
Metapathway biotransformation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the eyebrow	HPO Gene-Disease Associations	1.0	null
abnormality of skin physiology	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lamellar ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31515
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24861
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.44139
Hydrogen Ion	HMDB Metabolites of Enzymes	1.0	null
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165874
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.18447
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52989
EP300	ENCODE Transcription Factor Targets	1.0	null
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13481
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956794
Tafamidis	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041066
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309928
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14805
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.5299
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.78482
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47729
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01459
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93001
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71606
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sapropterin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.63
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17812
spinal canal and spinal cord meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.50798
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84699
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25286
Defective CYP1B1 causes Glaucoma	Reactome Pathways 2014	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
icosanoid metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112764
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1416
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diseases of metabolism	Reactome Pathways 2024	1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870328
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181954
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
Forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34769
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26343
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061258
sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09827
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98298
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Indomethacin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32047
STL321288	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.83637
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15813
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10523
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09436
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8449
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.047
HCC1143	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14642
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
HSC4	DepMap CRISPR Gene Dependency	1.0	3.26915
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vohwinkel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
Flexor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909099
Gangrene	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20561
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0239
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043219
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76554
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Tofacitinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
P31FUJ	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09338
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96537
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14376
Ewing's sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Starch utilization system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09966
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27533
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22339
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69777
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57037
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0041
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7987
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060969
Lack Of Skin Elasticity	DisGeNET Gene-Phenotype Associations	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18292
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40267
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850914
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XK-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Z32036776	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.5
hsa-miR-663	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.56354
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.73011
X-linked chondrodysplasia punctata 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49092
abnormality of cells of the erythroid lineage	HPO Gene-Disease Associations	1.0	null
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.023896
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94022
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2076
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94938
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31465
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.257
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02755
ABL127	DeepCoverMOA Drug Mechanisms of Action	1.0	0.62
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99605
VU 0364439	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045923
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990112
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34549
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105219
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38437
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.77494
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34024
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
KDM5B	ENCODE Transcription Factor Targets	1.0	null
case	GeneRIF Biological Term Annotations	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94384
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09016
PARP2_KD_GSE43981_676_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04176
GATA1	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05961
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.083057
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
SNU668	DepMap CRISPR Gene Dependency	1.0	4.51221
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53349
scrub typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.35681
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057839
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114232_10_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16435
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8048
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845759
hsa-miR-193a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70507
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5663_KD_HOXD13_SRP256218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.84729
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051169
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37893
hsa-miR-423-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.093815
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955009
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.28585
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC1	DepMap CRISPR Gene Dependency	1.0	3.70559
ion binding	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CW2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87205
congenital nonbullous ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186072
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29599
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15287
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20491
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29287
Iclaprim	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
Acrokeratosis verruciformis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.777
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46768
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046617
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19103
Phase I - Functionalization of compounds	Reactome Pathways 2024	1.0	null
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78632
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935358
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876703
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.264872
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.36
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16469
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
in situ carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304503
Subcutaneous tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
MV411	DepMap CRISPR Gene Dependency	1.0	2.10366
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854768
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61362
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992572
sepsis	HPO Gene-Disease Associations	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65163
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08171
Trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19073
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08698
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08507
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN229	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76368
GSE246983_1_v_0_cdk12_human	RummaGEO Gene Perturbation Signatures	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077846
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Enterovirus 71_4Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01003
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_10230_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.47633
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902176
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47767
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0698
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.393
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31784
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08102
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872794
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Arachidonic acid	HMDB Metabolites of Enzymes	1.0	null
208f	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4917
EW-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.27645
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4065
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86929
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60968
Lung squamous cell carcinoma_LUSC_TCGA-22-0944-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal elasticity of skin	HPO Gene-Disease Associations	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26655
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07334
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8462
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4669
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.55789
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028215
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flexor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26128
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78982
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0461
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.15745
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935358
ACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32837
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862797
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47043
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42499
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47828
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13262
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.176
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322779
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54736
abnormality of the head	HPO Gene-Disease Associations	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Ralfinamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58659
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30745
MYC	ENCODE Transcription Factor Targets	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04535
Prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3571
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9263
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08102
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.65227
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.266926
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.4575
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842577
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45592
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05397
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60999
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4896
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07999
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37483
chr19_15514361_T_C_b38	GTEx eQTL 2025	1.0	1.0946
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46884
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02937
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
EN	DepMap CRISPR Gene Dependency	1.0	3.3173
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0014
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46768
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
hyperkeratosis	HPO Gene-Disease Associations	1.0	null
Kibra-Ex-Mer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15065
extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432608
Epithelial basement membrane dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
Ruxolitinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Defective CYP19A1 causes Aromatase excess syndrome (AEXS)	Reactome Pathways 2014	1.0	null
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	1.52364
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911232
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03288
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4697-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2962
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
Ppes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27016