association	dataset	threshold value	standardized value
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
four	GeneRIF Biological Term Annotations	1.0	null
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
hsa-miR-3140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-577	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910301
their	GeneRIF Biological Term Annotations	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75887
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
3'-UTR-mediated mRNA stabilization	GO Biological Process Annotations 2023	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977919
Spermatocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
Enterovirus 71_4Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.97368
hsa-miR-4491	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2143
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
hsa-miR-543	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Azoospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4578
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	2.88009
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8013
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.454663
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.447
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
seems	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870591
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19037
spermatogenesis	GeneRIF Biological Term Annotations	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838986
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5246
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.409966
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
severe	GeneRIF Biological Term Annotations	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
16397242-Table1	GeneSigDB Published Gene Signatures	1.0	null
Gonadoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
azfc	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
male	GeneRIF Biological Term Annotations	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
hsa-miR-3614-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-4475	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5901
removing	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4733-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
testis	GeneRIF Biological Term Annotations	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1469
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PUM2	Pathway Commons Protein-Protein Interactions	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56482
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
hsa-miR-491-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
daz4	GeneRIF Biological Term Annotations	1.0	null
cannot	GeneRIF Biological Term Annotations	1.0	null
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0876
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19037
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-362-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-513a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
15832406-Table6	GeneSigDB Published Gene Signatures	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
reproductive process	GO Biological Process Annotations 2015	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40591
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
polymorphic	GeneRIF Biological Term Annotations	1.0	null
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7744
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84979
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1954
hsa-miR-206	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96528
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
Male Sterility	DisGeNET Gene-Phenotype Associations	1.0	null
copy	GeneRIF Biological Term Annotations	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8496
hsa-miR-1288	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.49
mRNA stabilization	GO Biological Process Annotations 2025	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43695
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Seminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Gynecomastia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DZIP1	Pathway Commons Protein-Protein Interactions	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.239
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3879
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.43593
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-144	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
positive regulation of translational initiation	GO Biological Process Annotations 2025	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Partial Chromosome Y Deletion	DisGeNET Gene-Phenotype Associations	1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-4307	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of translational initiation	GO Biological Process Annotations 2023	1.0	null
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
organelle	GO Cellular Component Annotations 2015	1.0	null
highly	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1601
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
BOLL	Pathway Commons Protein-Protein Interactions	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4597
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
hsa-miR-3669	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.631719
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03458
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Y-linked spermatogenic failure 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
required	GeneRIF Biological Term Annotations	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31996
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839508
Synergid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
DAZL	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4777-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.56252
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
daz3daz4	GeneRIF Biological Term Annotations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.55621
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96528
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
RNA recognition motif domain	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
common	GeneRIF Biological Term Annotations	1.0	null
mRNA binding	GO Molecular Function Annotations 2023	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Small Testicle	DisGeNET Gene-Phenotype Associations	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870591
impairment	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4516	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9763
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gamete generation	GO Biological Process Annotations 2015	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
hsa-miR-4434	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548q	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.059182
46,XY sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.18136
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.427
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Syndromic microphthalmia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
among	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-500a	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
hsa-miR-452	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.661
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
deletion	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4645-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.522
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11772
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of translation	GO Biological Process Annotations 2025	1.0	null
daz2	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.676
subdeletions	GeneRIF Biological Term Annotations	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3658
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3391
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7657
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
hsa-miR-1269	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7039
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1985
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4740-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
Theca externa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
thus	GeneRIF Biological Term Annotations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-1	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
promoted	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3827
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
IPAF inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11772
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9304
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
16449976-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
cellular process	GO Biological Process Annotations 2015	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36616
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
hsa-miR-196b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
fertility	GeneRIF Biological Term Annotations	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910301
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
hsa-miR-548e	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.05
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
nucleus	GO Cellular Component Annotations 2015	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-3065-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17261
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0876
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
distal	GeneRIF Biological Term Annotations	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9983
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-634	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
infertility	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4778-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Non-Obstructive Azoospermia	DisGeNET Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4790-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95965
Prostate adenocarcinoma_PRAD_TCGA-FC-7708-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3851
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3256
Oligospermia	DisGeNET Gene-Disease Associations	1.0	null
bpy22bpy23	GeneRIF Biological Term Annotations	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925792
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4274	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Infertility, Male	HuGE Navigator Gene-Phenotype Associations	1.0	null
Syndromic microphthalmia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
positive regulation of translation	GO Biological Process Annotations 2023	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.625
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
daz	GeneRIF Biological Term Annotations	1.0	null
Dysgerminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
variant	GeneRIF Biological Term Annotations	1.0	null
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12685
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of translational initiation	GO Biological Process Annotations 2023	1.0	null
mRNA stabilization	GO Biological Process Annotations 2023	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2019
hsa-miR-561	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42995
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839508
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ESRRA_01_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62834
MLXIP_01_92	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6966
binding	GO Molecular Function Annotations 2015	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
Nucleotide-binding alpha-beta plait domain	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-613	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2559
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
hsa-miR-500b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
mRNA 3'-UTR binding	GO Molecular Function Annotations 2023	1.0	null
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-28-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Male Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7713
496100482_PCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	13.1554
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977919
hsa-miR-4657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877848
Hereditary spastic paraplegia 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
hsa-miR-488	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
molecular_function	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-557	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
cell differentiation	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3942-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4320	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
lacks	GeneRIF Biological Term Annotations	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.56252
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32899
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-509-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
hsa-miR-3907	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of translational initiation	GO Biological Process Annotations 2025	1.0	null
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35164
AKT2_knockdown_44_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73772
Male infertility	WikiPathways Pathways 2024	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9344
oligospermia	GeneRIF Biological Term Annotations	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2188
hsa-miR-3920	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4772
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9412
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2655
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4531	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7077-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cornelia de Lange syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
hsa-miR-548f	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
copies	GeneRIF Biological Term Annotations	1.0	null
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
hsa-miR-4799-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC3960207-oncotarget-05-0264-s002.xls-rank_down_foxp3_symb-Supplementary_Table_2_Genes_significantly_differentially_expressed_between_the_SK-MEL-28-FOXP3_and_SK-MEL-28-EV_clones_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-3974	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC7825356-8844261.f3.docx-107-TGIF2LY_TGIF2LY	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1584
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mRNA 3'-UTR binding	GO Molecular Function Annotations 2025	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2642
Phosphoglycerate kinase 1 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2198
hsa-miR-3171	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2837
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7866
biological_process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-1261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CTCF	ENCODE Transcription Factor Targets	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03081
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
46,XY sex reversal 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.631
products	GeneRIF Biological Term Annotations	1.0	null
GSE102132_0_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7664
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
15869706-TableS2	GeneSigDB Published Gene Signatures	1.0	null
3'-UTR-mediated mRNA stabilization	GO Biological Process Annotations 2025	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924096
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12141
hsa-miR-4529-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.835
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1195
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5159
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
hsa-miR-548a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3835
20670856-Table2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4726-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
all	GeneRIF Biological Term Annotations	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.89448
hsa-miR-1269b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1584
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oligospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Partial androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
cellular_component	GO Cellular Component Annotations 2015	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.3113
hsa-miR-550b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
hsa-miR-507	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5241
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8236
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8309
mRNA binding	GO Molecular Function Annotations 2025	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.62588
doublets	GeneRIF Biological Term Annotations	1.0	null
Synaptic vesicle protein transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
chromosome	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4638-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
QKI	Pathway Commons Protein-Protein Interactions	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
men	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-629	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7143
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941787
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
496100627_TCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.04697
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-432	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6429
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-4515	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
15814623-Table3	GeneSigDB Published Gene Signatures	1.0	null
20208059-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-526b	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
male gamete generation	GO Biological Process Annotations 2015	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56324
chilean	GeneRIF Biological Term Annotations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6953
hsa-miR-4635	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Aromatase excess syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
Mitochondrial cloud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15257931-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877317
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
seem	GeneRIF Biological Term Annotations	1.0	null
rna binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC-1937 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
hsa-miR-196a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397