association	dataset	threshold value	standardized value
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.62534
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4981
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.39617
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26779
MTF2	ChEA Transcription Factor Targets	1.0	null
RNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90538
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.77212
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050892
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99102
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8059
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79554
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618
SKOV3	CCLE Cell Line Gene Expression Profiles	1.0	1.55185
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946077
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96635
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59656
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37155
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cul4-RING E3 ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
DMS53	CCLE Cell Line Gene Expression Profiles	1.0	1.42846
Nuclear RNA export factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93644
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50949
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1519
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07341
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4859
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30229
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300906
hsa-miR-630	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74624
hsa-miR-1	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09462
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33579
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.876055
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNNI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13165
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95002
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265088
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050892
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1-E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06183
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39178
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24433
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30443
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176144_0_v_1_zfc3h1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24875
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22205
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52812
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00178
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61782
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_CTCF_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14772
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26301
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.356689
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50315
PMC3117129-mp2010119x6.xls-CRS_Hpc-Unnamed_5_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20448
RUNX2	ChEA Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4216
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879278
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16357
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3145
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41127
HLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08463
kidney	HPA Tissue Gene Expression Profiles	1.0	0.971959
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053678
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5278
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57361
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14123
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11248
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17323
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056852
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76166
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.63116
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63854
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59956
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ChEA Transcription Factor Targets	1.0	null
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.9207
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH1	CCLE Cell Line Gene Expression Profiles	1.0	1.39823
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.71549
PMC7825356-8844261.f3.docx-55-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218727_0_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94505
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45376
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835461
TP63_01_201	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.2491
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23221
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34019
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89838
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4304
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975759
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5682-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.90375
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08597
hsa-miR-770-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3149
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
PPAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72225
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2743
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25777
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12792
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28993
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	2.00845
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-952 (CCNF)	NURSA Protein Complexes	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63789
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03232
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4457
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40226
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ddb1	GeneRIF Biological Term Annotations	1.0	null
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8239
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00473
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0488
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.28563
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8315
Sarcoma_SARC_TCGA-HB-A5W3-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1805
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8235
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03576
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0547
resembles	GeneRIF Biological Term Annotations	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11994
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45203
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43204
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.36
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28246
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21917
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19834
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16814
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11184
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.97268
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AM38	CCLE Cell Line Gene CNV Profiles	1.0	1.58461
hsa-miR-2052	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03795
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17558
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931099
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52894
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90909
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49197
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04971
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2125
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2269
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68933
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE208722_0_v_1_mkrn3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.63925
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.705949
ERGIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53174
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28423
hsa-miR-139-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976852
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13082
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.82674
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1685
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0656
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913887
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43901
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19324
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871939
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.15458
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3778-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7436
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56042
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69985
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83201
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.8655
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12757
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20371
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52659
Lung squamous cell carcinoma_LUSC_TCGA-39-5019-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-206	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28371
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24541
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80866
Learning Disorders	CTD Gene-Disease Associations	1.0	1.1485
TMSB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94139
CTCF	ENCODE Transcription Factor Targets	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052693
Blue cone monochromacy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37107
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.4855
SKRC20	CCLE Cell Line Gene Expression Profiles	1.0	2.63121
SUSA	DepMap CRISPR Gene Dependency	1.0	4.32328
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3207
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20325
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57789
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4394
hsa-miR-371b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893078
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206622
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15858
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCT116	DepMap CRISPR Gene Dependency	1.0	2.00057
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
5637	CCLE Cell Line Gene Expression Profiles	-1.0	-3.54589
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95651
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1297
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
characterizes	GeneRIF Biological Term Annotations	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13383
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09183
cul4associated	GeneRIF Biological Term Annotations	1.0	null
FADU	DepMap CRISPR Gene Dependency	1.0	2.86055
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9157_OE_PHACTR1_SRP343641	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4497
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5116-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26818
ARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21914
hsa-miR-613	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.37476
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32176
H3K9me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Cul4A-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.672
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06341
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297013
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913887
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.18384
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3074-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.21392
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PC14	CCLE Cell Line Gene CNV Profiles	1.0	2.42262
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37851
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	2.01605
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4274	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4864
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79478
Inflammation	CTD Gene-Disease Associations	1.0	1.33464
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27277
nanog_16518401_mesc_lof_mouse_gpl1261_gds1824	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.050085
Lung squamous cell carcinoma_LUSC_TCGA-85-8052-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	2.37844
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38307
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13258
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04929
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02744
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64905
REST	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3617	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.81967
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65455
BHT101	CCLE Cell Line Gene CNV Profiles	1.0	1.72839
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00389
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4711
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8406-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	196.431
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.480091
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ES4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54876
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302756
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28839
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63_01_199	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.48923
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65473
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51532
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8299
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52241
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4977-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275256
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27118
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959569
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85593
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.04664
PMC3590650-bjc2012518x7.xls-Sheet1-Supplementary_Table_S3_list_of_predicted_target_genes_for_miR29c_present_in_both_PITA_and_Targetscan_predictions_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277984
L540	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8331
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.16574
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31408
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04697
Fetal Resorption	CTD Gene-Disease Associations	1.0	1.20558
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50157
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36632
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YSCCC	DepMap CRISPR Gene Dependency	1.0	3.84832
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999492
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.833817
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239307
cullin-RING ubiquitin ligase complex	GO Cellular Component Annotations 2023	1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00505
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.33342
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
IGROV1	CCLE Cell Line Gene Expression Profiles	1.0	2.25971
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-678	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14284
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3766
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05267
hsa-miR-618	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSS131R	DepMap CRISPR Gene Dependency	1.0	12.9954
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23198
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.434
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14639
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03047
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840528
ATP5MK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1848
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80006
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73054
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46077
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10036
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
hsa-miR-432	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SLR25	CCLE Cell Line Gene Expression Profiles	1.0	3.19026
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.26912
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907247
TEN	CCLE Cell Line Gene Expression Profiles	1.0	2.13764
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.56815
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.44604
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47781
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861152
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32041
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.36638
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29644
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26333
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11625982-AJH-100-10-s001.pdf-9-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059275
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55878
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9534
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64762
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7225
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04186
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09842
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.956206
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32327
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17821
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OELE	CCLE Cell Line Gene Expression Profiles	1.0	1.45278
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77323
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WD40/YVTN repeat-like-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.92365
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24433
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4639-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74731
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17665
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04175
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.74204
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37811
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5091
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52492
Kidney Chromophobe_KICH_TCGA-KO-8411-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44334
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7457511__F9	PFOCR Pathway Figure Associations 2023	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21934
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70139
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5269
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
spleen	HPA Tissue Gene Expression Profiles	1.0	0.830182
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52272
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36076
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50494
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06028
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03297
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91003
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.45282
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76143
product	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1229	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92249
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Perturb_2738_KD_NIK_SRP332892	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.90835
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7327
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.09415
Liver Diseases	CTD Gene-Disease Associations	1.0	1.23296
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38688
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NCIH2172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97305
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.994041
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40428
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02897
OC315	CCLE Cell Line Gene Expression Profiles	1.0	1.84944
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.02077
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3185
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03861
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ED-43-XF39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221731
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39797
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64203
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAOY	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3017
FADU	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09791
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49092
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11633
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45193
NCIH1793	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26915
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68236
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47641
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02025
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_743_KD_RASSF2_SRP233387	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93434
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
Testicular Diseases	CTD Gene-Disease Associations	1.0	1.01099
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058011
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09355
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33124
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292394
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40654
H3K9me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43152
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7129-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289491
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
hsa-miR-4639-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89051
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0881
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879278
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.994041
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5689
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Translation initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
GSE130396_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.33189
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69361
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11783
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23066
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43868
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01506
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20898
factors	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830611
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3749
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58414
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967413
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.127
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8692
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38134
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4976-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59085
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19165
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12811
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34758
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19464
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50672
BICR16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63612
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45969
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85765
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054741
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4286
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898787
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16983
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47973
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46728
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57672
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99687
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9128
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8935
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36931
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.854
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58757
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03292
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64881
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854417
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44092
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.01549
menadione_mus musculus_gpl1261_gds4171	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07705
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05563
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4744	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281705
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.994041
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38692
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41811
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82986
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67254
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14712
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25272
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4924
PITX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50254
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15988
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30495
CUX1	ChEA Transcription Factor Targets	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7244
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8853
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61385
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01524
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12146
Sarcoma_SARC_TCGA-DX-A3U9-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
DB	DepMap CRISPR Gene Dependency	1.0	2.56671
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3058
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90657
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95891
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31395
CTCF-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.14473
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32367
GSE144484_0_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20821
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944417
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262552
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.36857
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
HS939T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53808
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.49308
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09235
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15994
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3042
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75907
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22208
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36324
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.667
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42045
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02868
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.866686
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.392002
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4531	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06053
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68628
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835461
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59223
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05722
sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.50052
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85693
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.6519
menadione_mus musculus_gpl1261_gse23725	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.90492
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16597
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32236
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11248
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5104-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15551
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cul4-RING E3 ubiquitin ligase complex	GO Cellular Component Annotations 2023	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1975
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.34434
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3892
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3918
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.803
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28253
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	191.292
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827241
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99619
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71978
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39373
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5588-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43048
CAS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10946
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38251
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32969
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55038
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3735
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04438
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
PLAGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23762
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875154
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18689
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26301
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.29936
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08441
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC251	CCLE Cell Line Gene Expression Profiles	1.0	1.48185
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC11876530-3214633.f4.pdf-130-ZMAT1_ZMAT1	Rummagene Transcription Factor Associations 2026	1.0	null
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24826
KP1N	DepMap CRISPR Gene Dependency	1.0	2.36915
Lung squamous cell carcinoma_LUSC_TCGA-90-A59Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87356
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34204
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89233
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922919
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15475
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48434
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913887
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862128
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01293
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80466
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.039
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84239
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9586
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893062
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36906
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23062
functionally	GeneRIF Biological Term Annotations	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60657
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.2737
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04047
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51564
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36124
LBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36953
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07776
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4967-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204544
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.994041
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944417
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95317
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899679
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79003
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79592
PMC7457511__F9	PFOCR Pathway Figure Associations 2024	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.2081
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53429
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08735
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.06442
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452969
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25086
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41315
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970317
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47834
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989638
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23598
dcaf12	GeneRIF Biological Term Annotations	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CAOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48651
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09328
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.118
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.870471
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35142
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62907
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5134
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
496100558_PCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.65281
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07778
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-591	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.43627
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37673
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7394
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.41315
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.927
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16258
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26293
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1043
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06834
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20898
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.468
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48765
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51116
STAT3	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26814
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03465
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
WD40 repeat	InterPro Predicted Protein Domain Annotations	1.0	null
THP1	CCLE Cell Line Gene Expression Profiles	1.0	1.37671
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90529
IGF1R-20145208-DFB-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58646
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.994041
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WD40-repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23149
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11342283-mmc4.xlsx-LPS_vs_ATP_LPS-UCSC_RefGene_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69821
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02331
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35208
Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24677
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63508
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988038
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47826
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4534
C16orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92705
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2131
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73631
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07397
NCIH841	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86294
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92219
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26213
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87587
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.17662
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.2158
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.29795
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64229
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262061
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6626
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09311
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5181-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.88077
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.886467
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59613
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.25
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.08296
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974067
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.16137
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19395651-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45024
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904984
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.05591
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84243
OC314	CCLE Cell Line Gene Expression Profiles	1.0	1.67257
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32446
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39231
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867106
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9877
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52059
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	2.20945
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HEKTE	CCLE Cell Line Gene Expression Profiles	1.0	1.79649
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835461
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23663
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.169
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297264
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12836
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32193
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
NFKB1_01_167	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60287
DEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.44676
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36554
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913887
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CCNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43011
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80614
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57634
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.886664
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7001
Sarcoma_SARC_TCGA-DX-A48L-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Handedness (Right-handed vs. non-right-handed)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GOTO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7063
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36084
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3494
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04326
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEKI	DepMap CRISPR Gene Dependency	1.0	5.18754
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36491
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.06608
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.25557
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.48995
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.391885
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26884
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_female_2w	MoTrPAC Rat Endurance Exercise Training	1.0	1.76072
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7632
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27738
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.859362
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53225
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.22632
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13419
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243302
Primitive endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13947
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
SLR26	CCLE Cell Line Gene Expression Profiles	1.0	1.60998
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54848
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
WM1799	DepMap CRISPR Gene Dependency	1.0	2.56202
NCIH1734	CCLE Cell Line Gene CNV Profiles	1.0	1.35099
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15527
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276003
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67082
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88162
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.06977
NCIH727	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73312
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32902
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04243
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03232
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3231
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01161
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03185
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.3476
OC316	CCLE Cell Line Gene Expression Profiles	1.0	1.72567
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91321
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40095
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38894
Epi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.994041
cullin-RING ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06216
Human cytomegalovirus infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3512
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.10399
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE233679_5_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	3.68886
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BJAB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66456
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.53114
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897797
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	1.55192
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87207
azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04335
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cullin-RING ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68847
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.92614
RNF2-27304074-CHIP-SEQ-NSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3241
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1433
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33434
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9964
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41313
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14115
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223422
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839159
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1195
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243107
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-410	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
E2F6	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828147
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46681
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U2OS	DepMap CRISPR Gene Dependency	1.0	24.1448
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.566
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26165
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943709
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
rectum	HPA Tissue Protein Expression Profiles	1.0	0.994041
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01804
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32743
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_14310_KD_CD83_SRP178846	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899679
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828011
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.07732
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3200-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02161
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31849
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PMC10994228-MOL2-18-939-s001.pdf-22-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.845824
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879278
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21161
Necrosis	CTD Gene-Disease Associations	1.0	1.51911
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27558
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87639
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.101455
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.994041
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95885
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06248
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57012
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68252
SUDHL10	CCLE Cell Line Gene CNV Profiles	1.0	2.48477
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29966
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.50828
Hypertrophy	CTD Gene-Disease Associations	1.0	1.13621
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.53296
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.278
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EW8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53116
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67973
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205095
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.00179
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97888
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99527
hsa-miR-3123	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06079
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89803
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72574
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77894
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	270.576
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36542
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45376
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	0.976735
hsa-miR-4435	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
OSRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.38452
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12654
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16735
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS53	DepMap CRISPR Gene Dependency	1.0	2.58951
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0434
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57614
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45639
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.0311
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49433
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.994041
hsa-miR-3673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78127
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.34183
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4469
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45077
VMRC-RCZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42675
closely	GeneRIF Biological Term Annotations	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1035
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39596
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.68063
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.857098
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74996
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34399
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59322
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827241
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34776
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867106
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAW42	CCLE Cell Line Gene Expression Profiles	1.0	1.97483
Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288246
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2773
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30495
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.56851
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
17682054-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83163
MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861482
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6635
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16239
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12792
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-146b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42198
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17665
NCI-H209	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050783
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69361
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8537
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857882
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16761
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22606
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982668
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07413
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48231
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85418
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277534
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920906
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31831
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
MDAMB361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57799
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77661
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.878441
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14391
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.53417
hsa-miR-4712-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FAM124A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64385
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27589
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
other	GeneRIF Biological Term Annotations	1.0	null
Behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34115
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.77192
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73131
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02868
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040257
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61137
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61043
HCFC1	ENCODE Transcription Factor Targets	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919014
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11248
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273673
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-2054	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15355
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.19477
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71461
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17335
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48468
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	1.74681
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273162
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77336
PMC11399095-44161_2024_532_MOESM14_ESM.xlsx-Sheet1-Supplementary_Table_13_DEG_in_the_AA_borderzone_in_AF_vs_SR_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4690-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28874
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18963
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13204
MRPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82181
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51601
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960652
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06775
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24453
RCOR1	ChEA Transcription Factor Targets	1.0	null
TOLEDO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54193
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923621
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97019
most	GeneRIF Biological Term Annotations	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908191
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44745
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874396
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
PIP4P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32323
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59339
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87329
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58469
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50028
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11975
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.94028
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973938
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954966
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
PMC11148097-41698_2024_569_MOESM2_ESM.pdf-223-IRF3_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45352
Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0766
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.51094
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32363
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05867
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881774
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37313
RKN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4669
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	2.40963
SOX2	ChEA Transcription Factor Targets	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88339
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Deprivation amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22793
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18214
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09744
gallbladder	HPA Tissue Gene Expression Profiles	1.0	1.02492
GABARAPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2442
Sarcoma_SARC_TCGA-X6-A7WA-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59716
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02868
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29981
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59142
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.42183
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262276
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19547
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2611
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57763
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46299
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990839
ERG	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP92	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42139
NCIH1048	CCLE Cell Line Gene Expression Profiles	1.0	1.3665
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29187
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.59061
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69947
ZCWPW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30987
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82542
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923621
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27224
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.77815
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488