association	dataset	threshold value	standardized value
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12368
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.526
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59734
abnormal nephron morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K75330923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06597
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40731
Sclerocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
HSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3420_KO_USP7_SRP330182	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21882
ME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00405216
BRD-K43936062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09961
mode of inheritance	HPO Gene-Disease Associations	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56962
BRD-K97056771_HY-11007_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal kidney collecting duct morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.933867
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	1.50481
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09098
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69095
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39923
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39318
GTEX-Q734-0826-SM-48U1G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1309
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stellate ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
TAF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K50162138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39453
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NECTIN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697996
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23615
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.370257
BRD-K04886976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25922
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63972
IL9R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00904772
NEK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565699
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40747
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.55899
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32511
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25527
KCNA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00802876
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3381
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31979
RAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00327559
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41771
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36853
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cadherin	InterPro Predicted Protein Domain Annotations	1.0	null
HCST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580203
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739802
Atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876793
BRD-K45252063_Clofibrate_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBE2Q2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685424
Spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829043
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2973_KD_Nap1l2_SRP304879	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73072
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09106
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34393
Raf-1_OE_GDS1925_166_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206779_1_v_3_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Human - Fetal Development - L2 - Muscle-Schwann cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066609
developmental process	GO Biological Process Annotations 2015	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14386
hsa-miR-4436b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
ILF2_02_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60039
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52844
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K79604175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06693
BRD-K82868643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90246
BRD-A44551378_LFM-A12_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
SKNMC	CCLE Cell Line Gene Expression Profiles	1.0	2.9788
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548761
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257237
DHRS11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671102
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31946
R3HDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00894286
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13792
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2-BFI	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90124
GA-94-MC54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329434
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(ZEBOV)_1hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.38582
BRD-K47984776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18254
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993832
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4346
Ehlers-Danlos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75679095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32781
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01798
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05112
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94155
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.12566
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5444-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976274
Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.185
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Perturb_17590_OE_Ppard_SRP230295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.61966
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46389
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia involving bones of the extremities	HPO Gene-Disease Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89209981_(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)(4-(hydroxydiphenylmethyl)piperidin-1-yl)methanone_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Van Maldergem syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PDK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520509
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03451
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.593
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12268
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40865
signal transduction	GO Biological Process Annotations 2015	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.907352
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00974785
SERPINB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491531
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23037
BRD-K02130563_S1030_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50138
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11957
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00719702
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K02781189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.215
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48706
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47648
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46348
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03597
PRPF38B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538421
tube morphogenesis	GO Biological Process Annotations 2015	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85471
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948632
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.73581
CD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716713
Perturb_7543_KD_HSF1_SRP275505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.29041
Interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
short long bone	HPO Gene-Disease Associations	1.0	null
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.35368
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35456
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.705
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
PRSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00572358
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01225
HPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00428087
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49215099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2189
Sid2-Mob1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.07915
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC181	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670484
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06806
PMC4450212__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.64847
CADM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542436
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plateletcrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25759
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33429
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K45952474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44152
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.29246
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917461
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05161
Perturb_4467_KO_Cnr1_SRP346447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.29185
TBP	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10281040-mmc1.pdf-6-KLF12_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
NEK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00440586
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M1-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GCKR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611238
chr11_6670531_T_C_b38	GTEx eQTL 2025	1.0	1.27935
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32760954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74667
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62226
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952878
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Marfan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874085
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1074
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30085
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064117
35 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09983
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04534
BRD-K16937802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17918
BRD-A75301702_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A86977540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32183
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.12727
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1777
PMC6295312__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35254
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987554
BRD-K72462751_C-1_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24772
abnormality of the clavicle	HPO Gene-Disease Associations	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50539
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7738566__F3	PFOCR Pathway Figure Associations 2023	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917779
DRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561282
PMC5857600__F5	PFOCR Pathway Figure Associations 2024	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7352
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.745
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	3.04789
abnormality of the maxilla	HPO Gene-Disease Associations	1.0	null
hearing impairment	HPO Gene-Disease Associations	1.0	null
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
IMPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00839044
BRD-K35614154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27038
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.341
BRD-K79090631_CGP-60474_MDAMB231_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65255
Perturb_5574_KO_NFKBIA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.35501
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914694
hsa-miR-525-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.43015
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594372
Ethoxzolamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
tissue morphogenesis	GO Biological Process Annotations 2015	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916854
BRD-K58728497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06055
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983376
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873429
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47137
Joint Laxity	DisGeNET Gene-Phenotype Associations	1.0	null
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2025	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
narrow chest	HPO Gene-Disease Associations	1.0	null
BRD-K11927976_ER 27319 maleate_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
talipes	HPO Gene-Disease Associations	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34483
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38249
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0086
SPTLC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477668
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25503
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.17675
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05846874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68047
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261784
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51306
BRD-K76518272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33395
PMC7738566__F3	PFOCR Pathway Figure Associations 2024	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13872
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23723
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX3_01_27	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59837
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32717
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.184
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STK35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567383
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADGRG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00735992
ptosis	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91377
Perturb_15232_OE_Zscan4f_SRP229595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599209
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09911
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Van Maldergem Wetzburger Verloes syndrome	CTD Gene-Disease Associations	1.0	2.88009
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02272
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29616
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15761
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56904
post-anal tail morphogenesis	GO Biological Process Annotations 2015	1.0	null
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44484
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04005364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96147
short metacarpal	HPO Gene-Disease Associations	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8913
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Periventricular nodular heterotopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.544
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93538
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.684849
PAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685856
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
Basal ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85276
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.279195
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K46056750_AZD-7762_HS578T_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33133
TADA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00794622
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
BRD-K46428124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9587
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
Perturb_9754_KO_Cfb_SRP333300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.6531
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25372
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885189
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524169
BRD-K62229896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05199
JUN	ENCODE Transcription Factor Targets	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980519
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866819
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	3.20282
impaired branching involved in ureteric bud morphogenesis	MPO Gene-Phenotype Associations	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63782
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13723
Narrow Thorax	DisGeNET Gene-Phenotype Associations	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0085
Schwann cell_Skeletal muscle_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889958
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.107677
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29221
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-N-FI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bilateral frontoparietal polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K68065987_MK-2206_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838736
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829043
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12067
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RDH13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496195
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887499
Genistein	DeepCoverMOA Drug Mechanisms of Action	1.0	0.6
abnormality of the cerebral white matter	HPO Gene-Disease Associations	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.8015
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Panhypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PKN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.010975
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3259
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	363.161
PMC6888893-41422_2019_228_MOESM9_ESM.xlsx-DEGs_of_HEC_aEC_RUNX1-aEC_CXCR4__genes_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297738
XA-82-BM12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214352
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02502
GSR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514475
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218908
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K68336408_Tyrphostin AG 1478_H1299_6.0_h_56.7799987793_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59821372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10187
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28486
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06181
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00425601
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39185
GLYCTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00841474
abnormal mechanoreceptor morphology	MPO Gene-Phenotype Associations	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K42968343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17567
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926247
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00512
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537044
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869718
LRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062315
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04194
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954807
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1805
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10768
GSE103124_2_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68202742_trichostatin A_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7982
thoracic hypoplasia	HPO Gene-Disease Associations	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.40294
parbendazole-3799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.941646
Tracheomalacia	DisGeNET Gene-Disease Associations	1.0	null
PECAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00892876
SLC16A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561777
Congenital Epicanthus	DisGeNET Gene-Disease Associations	1.0	null
SMARCAL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00463996
IM-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2852_Mut_NRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08553
Congenital Clubfoot	DisGeNET Gene-Disease Associations	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80606
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.806
PIGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499836
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.980422
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.875
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219148
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0775
aplasia/hypoplasia of the ear	HPO Gene-Disease Associations	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.01605
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HLA-DOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647199
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tafluprost	DeepCoverMOA Drug Mechanisms of Action	1.0	0.98
BRD-K92428232_HY-50877_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPX7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00749333
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72396
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.53854
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11303
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57695
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02961
BRD-K31491153_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924399
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10504
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878027
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829043
TM6SF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671226
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14925
AZD 6482	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.5
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09466
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907154
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3021
Kidney renal clear cell carcinoma_KIRC_TCGA-GK-A6C7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5897
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16033
PI4K2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540168
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541277
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.21727
BRD-K14702616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13577
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
nervous system development	GO Biological Process Annotations 2025	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.920506
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850418
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.034472
Ehlers-Danlos syndrome spondylodysplastic type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18568
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laminin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
EGR1	ChEA Transcription Factor Targets	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.72234
Pharyngeal arch cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03606
PMC10652340-ACEL-22-e13915-s007.xlsx-FOXJ2-SYMBOL_FOXJ2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6093-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6087_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.7626
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44125
BRD-K93260425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6022
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.19705
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00796
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35557
MYC	ENCODE Transcription Factor Targets	1.0	null
FKBP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00434247
HIPK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bpe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16943
BRD-K24385654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20563
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tricuspid valve prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12876
PMC7021759-41467_2020_14682_MOESM10_ESM.xlsx-downregulated_genes-Table_S7_Dowregulated_genes_in_SKNMM_and_U2OS_cells_with_MYCN_induction_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
15257931-SuppTableD	GeneSigDB Published Gene Signatures	1.0	null
Cell hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
atrioventricular valve formation	GO Biological Process Annotations 2023	1.0	null
NMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636168
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
ion binding	GO Molecular Function Annotations 2015	1.0	null
DSCAML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00765985
PMC5682285-41467_2017_1744_MOESM10_ESM.xlsx-HUES9_KD-Unnamed_0_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	3.63522
Bestatin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11346
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25982
ATP13A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00380029
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63288
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37751
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70175
Perturb_17233_KD_KLF2_SRP389914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.76075
ERBB4	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13695
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00356737
RPS6KA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00841314
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081345
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
NCKAP1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505787
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21026
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25183
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855947
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9391581-mmc4.xlsx-KLF4_K409Q_vs_GFP-activated-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GJA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782996
BRD-K98437821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04271
ADH1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602189
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969621
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92438
BRD-K70505054_RANITIDINE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
abnormality of lower limb bone	HPO Gene-Disease Associations	1.0	null
TSSK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610272
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	1.0	1.49455
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25938
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99132
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_700_KO_INTS6_SRP299234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3246
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-484	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT3_KO_GDS4817_417_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846528
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83139
STAT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621726
BRD-K01980291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41262
MEX3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656505
RPS6KA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053211
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50138
BECN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480702
BRD-K34604637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5776
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51023
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07231
abnormality of the cerebral cortex	HPO Gene-Disease Associations	1.0	null
WT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716429
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93804
thoracico-abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
LTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581865
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HINT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508651
BRD-K87748094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38489
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53486
BRD-K53903639_480743.cdx_HT29_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neurofibroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51875
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03746
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	1.57408
hsa-miR-3144-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13655
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27633
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30251
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10744
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Icatibant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.62
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44881
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49142
FPGT-TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553902
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13104
13c4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABRR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608816
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39512
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03825
BRD-A29082194_GITOXIGENIN_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37471
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.67518
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93337
HMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.912378
TEAD4_02_40	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60039
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15268
Cloprostenol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02334
Aortic valve stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1729
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56147
BRD-K82082713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42226
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924451
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0092
IHO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567866
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14865
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15052
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0652
heart morphogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947516
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47598052_PP 1_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Microstomia	DisGeNET Gene-Disease Associations	1.0	null
PTGES	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599444
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01114
BRD-K14383477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01226
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907459
joint hypermobility	HPO Gene-Disease Associations	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15563106_-666_HEPG2_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
Hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04265
BRD-A59943784_Fluticasone propionate_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K81418486_vorinostat_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A48720949_TESTOSTERONE PROPIONATE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
wide nasal bridge	HPO Gene-Disease Associations	1.0	null
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.48767
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85862
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72296840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4095
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37078
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9648
BRD-K52911425_GDC-0941_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16184
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPRED2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00352796
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36851
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PDXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567207
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954749
Perturb_5850_KD_SUPT4H1_SRP076722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856769
Hypoplastic left heart syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55637
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
Heart endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NL-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.1939
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92955882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12792
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19861
Perturb_3240_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.586
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20397
abnormality of cranial sutures	HPO Gene-Disease Associations	1.0	null
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-178-ZNF365_ZNF365	Rummagene Transcription Factor Associations 2026	1.0	null
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.745
PMC5582996__F1	PFOCR Pathway Figure Associations 2023	1.0	null
SMYD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479773
GART	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771727
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.437
Cutaneous Finger Syndactyly	DisGeNET Gene-Disease Associations	1.0	null
Infantile Muscular Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55358
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.10863
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14888
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16062
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Human - Kidney - L1 - Schwann	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2851_Mut_NRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15879
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830303
BRD-K48845054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97949
BRD-K18724229_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14602
Perturb_3987_KO_Actb_SRP195587	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051671
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17760805-SuppTableS2a	GeneSigDB Published Gene Signatures	1.0	null
TMEM119	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00655755
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15644
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01917
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
neurogenesis	GO Biological Process Annotations 2015	1.0	null
Perturb_1168_KD_ETV6_ERP128093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96706
BRD-K21648400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00354
FCRL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00416806
GLB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00367568
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_109_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16212
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05503
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441455
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714382
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169099
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08096
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1498
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546237
Perturb_16078_KD_Kras_SRP270848	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_16810_KD_Setd7_SRP075653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43999
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880977
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40567
BRD-K44652223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14112
adherens junction	GO Cellular Component Annotations 2023	1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833588
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.75872
BRD-K41887762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0842
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13781
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.41682
ART3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808861
impaired branching involved in ureteric bud morphogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
BRD-K37080523_ISORESERPINE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
all	HPO Gene-Disease Associations	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LY334370	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06008
aplasia/hypoplasia of the clavicles	HPO Gene-Disease Associations	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24071
abnormal bone structure	HPO Gene-Disease Associations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.553286
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2604
BRD-K08307026_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thick mitral valve cusps	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53465
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_1-SUPPLEMENTARY_DATASET_1_AML3_AzaC_SigDiff_1147_Note_to_reviewers_-_view_these_files_as_xls_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Tubulinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07003
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JTE 013	DeepCoverMOA Drug Mechanisms of Action	1.0	0.88
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75913
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Short Fourth Metatarsal	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957458
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84362
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08795
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
IOSE80	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.931014
EGR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534928
BRD-K04010869_PROSTAGLANDIN A1_THP1_6.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	1.58475
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982733
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30886
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Wing disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
dilated renal tubule	MGI Mouse Phenotype Associations 2023	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04434
STAT6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00710822
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23645
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41321
GRK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594081
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835225
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4362
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95673
Heterotopia, Periventricular	DisGeNET Gene-Disease Associations	1.0	null
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36013
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.66
KCNB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699513
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82242
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0625
abnormal endochondral bone ossification	MPO Gene-Phenotype Associations	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.64174
Perturb_573_KO_Plod1_SRP321648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.61124
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22631
BRD-K92093830_Doxorubicin hydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843887
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.66179
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930574
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.922682
abnormal sternum ossification	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5566
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947072
BRD-K69932463_AZD8055_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9071_KD_HIF2A_SRP141017	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68213
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977818
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
PMC12321844-Supplementaryfile1.docx-0-GTF2IRD2B_GTF2IRD2B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
SCH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64605
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11151
MRGPRX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00905594
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903018
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934486
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.555
BRD-K12984952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35854
BL1242 (MAML2)	NURSA Protein Complexes	1.0	null
Leading edge of lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05045
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0487
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934486
NDT 9513727	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.62
GSE239747_2_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TPSAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00877019
BRD-K98418950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05543
TMEM82	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709932
Nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Lymphedema	ClinVar Gene-Phenotype Associations 2025	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.090775
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71194
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8610_KD_Camta1_SRP048702	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.15063
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
abnormal mitral valve morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_13913_KD_SLC45A4_SRP173763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.05992
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
Pseudoxanthoma elasticum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87746
Wide Cranial Sutures	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TEAD2_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
HS-578-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney cysts	MPO Gene-Phenotype Associations	1.0	null
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OSM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570588
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45874102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83691
BRD-K79090631_CGP-60474_MDAMB231_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94102
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.065
Weight Gain	CTD Gene-Disease Associations	1.0	1.17464
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30744
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28242
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526552
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12181
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255834
TRIM46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570969
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3509
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.684849
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17049
Narcolepsy	DisGeNET Gene-Disease Associations	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7285
KYSE-520	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59033
receptorligand	GeneRIF Biological Term Annotations	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4675
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37754
homophilic cell adhesion via plasma membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
ANO6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00778419
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
congenital onset	HPO Gene-Disease Associations	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15642
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066636
NFATC1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFV1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061413
Van Maldergem Syndrome	DisGeNET Gene-Disease Associations	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20258
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.20468
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055667
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925092
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53101
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00404609
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85501
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_7_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04903
DLG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492047
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4741_KD_Mettl3_SRP354177	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PATL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00698577
U2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0124095
ASH2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058396
Perturb_385_KO_IKKa_SRP229998	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
piperacillin-3939	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52414345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28136
PMC5798892-41421_2017_3_MOESM8_ESM.xlsx-down-regulated-Supplementary_Table_S3_Up-_and_downregulated_genes_in_ATF6-_-_hMSCs_compared_to_ATF6_hMSCs_late_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591743
BRD-A68175400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35988
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519347
Large Fontanelle	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7847
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940174
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K80803211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04751
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57179
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24584
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	202.384
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Noonan syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34272
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30071
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33947
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A49544621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38238
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29871
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964831
KCNK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601317
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01877
mch7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.69783
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83049611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60126
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229295
MALSU1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538742
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0842
rene1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
TUBB2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618241
LILRB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535586
STK24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570702
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CFTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595771
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31476
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
DMS53	DepMap CRISPR Gene Dependency	1.0	4.97504
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0189
Prostate adenocarcinoma_PRAD_TCGA-EJ-8468-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.41355
DVL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00742972
EIF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693799
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479965
Anal Stenosis, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
DOCK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721861
IL23A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00835726
HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8268
BRD-A75409952_wortmannin_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25218
abnormality of the zygomatic arch	HPO Gene-Disease Associations	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4487	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15853
Infertility, Male	CTD Gene-Disease Associations	1.0	1.1198
ATP5PB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555975
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
abnormal bone ossification	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
short clavicles	HPO Gene-Disease Associations	1.0	null
GABPB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525508
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942327
NB13	DepMap CRISPR Gene Dependency	1.0	6.32068
STH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00649816
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974903
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
ADRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481173
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.1115
PMC10291819-13287_2023_3380_MOESM10_ESM.pdf-22-KCNIP3_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.35789
BRD-K21910317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22023
Agenesis	DisGeNET Gene-Disease Associations	1.0	null
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
RPL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00938361
BRD-K64567246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06929
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.42466
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28701
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13668
cell migration involved in endocardial cushion formation	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02532
Lung adenocarcinoma_LUAD_TCGA-91-6829-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99647
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52657
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942213
Cortical Gyral Simplification	DisGeNET Gene-Phenotype Associations	1.0	null
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02698
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.23465
Postural orthostatic tachycardia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209691
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ENPP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00753312
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.749633
ALDH18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0036684
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37382
neurogenesis	GO Biological Process Annotations 2025	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476463
abnormal cortical gyration	HPO Gene-Disease Associations	1.0	null
AK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676718
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05784
BRD-K00615600_AG14361_NOMO1_6.0_h_25.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86938753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11069
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886216
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56021
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23754
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
Extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.383
cell migration involved in endocardial cushion formation	GO Biological Process Annotations 2023	1.0	null
HSD17B6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616547
sleep disorder	GWASdb SNP-Disease Associations	1.0	1.35896
TPRKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615609
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Edwards syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
HS683	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11794
CDK13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665939
Mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.419
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39909
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49388
SELPLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669875
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993736
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06301
postnatal growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_15853_KD_ETS1_SRP270313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967399
SLC22A18AS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717085
TEX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518286
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909177
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249906
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Van Maldergem syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.147
TLR10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578265
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79332
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
PHF8	ENCODE Transcription Factor Targets	1.0	null
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6854
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840651
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1066
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0144
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244745
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
GJA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00446235
BRD-K75806288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07044
Testolactone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
small kidney	MGI Mouse Phenotype Associations 2023	1.0	null
STMN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415774
Endocardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
DCLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525549
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
CZC-25146	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1999
ARNT_01_240	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66057
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
PMC9992472-41467_2023_36735_MOESM6_ESM.xlsx-Late_SOX11_gene_signature-Unnamed_1_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19830171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32238
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
PRKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560114
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81732
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.719909
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43213
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6778131-41467_2019_12494_MOESM13_ESM.xlsx-Figure_S3b-BCL2-MYC_Day_75_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34785
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61438422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8038
Vesicoureteral reflux	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CILP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730924
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.15033
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06981
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45445
PTP4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624312
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06096
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97312
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2025	1.0	null
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24055
GPNMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606986
MLE-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84393
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CATSPER3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560073
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81574
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5545-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36041
postnatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
ASGR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576123
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839921
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474007
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.487
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47284
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28869
BRD-K69840642_HDAC6 inhibitor ISOX_SW480_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24052
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00528
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02501
Anteriorly Placed Anus	DisGeNET Gene-Phenotype Associations	1.0	null
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923094
SAP30	ENCODE Transcription Factor Targets	1.0	null
motor neuron disease	GWASdb SNP-Disease Associations	1.0	0.787916
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23888
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01427
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.80108
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.337488
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234644
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
narrow forehead	HPO Gene-Disease Associations	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.415
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20284
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974046
BRD-K50140147_NVP-TAE684_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14507
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CXCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00420533
UBAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10093
microtia	HPO Gene-Disease Associations	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8642
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31155
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43389698_BMS-387032_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11774
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23449
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066189
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LNZ308	Achilles Cell Line Gene Essentiality Profiles	1.0	2.38613
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13814
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92003
SARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610031
abnormal lumbar vertebrae morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27664
Absence Of Pubertal Development	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K14711204_4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	3.26376
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45827
hsa-miR-3191	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
Perturb_14455_KO_Figla_SRP228490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K55946794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00109
CHD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058773
BRD-K54637865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0979
abnormal renal tubule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
onset	HPO Gene-Disease Associations	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045332
Wide Anterior Fontanel	DisGeNET Gene-Phenotype Associations	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HLF	DepMap CRISPR Gene Dependency	1.0	2.66353
YKG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17973
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27917
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Malignant peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.898595
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ossification involved in bone maturation	GO Biological Process Annotations 2015	1.0	null
Familial Mitral Valve Prolapse	DisGeNET Gene-Disease Associations	1.0	null
MBNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460814
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86728
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49061529_ETHYL-beta-CARBOLINE-3-CARBOXYLATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DGKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826865
decreased bone mineral content	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48046
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84104
FER	Pathway Commons Protein-Protein Interactions	1.0	null
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22732
abnormal facial shape	HPO Gene-Disease Associations	1.0	null
BRD-K60053695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71905
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25596
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pachygyria	HPO Gene-Disease Associations	1.0	null
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Caudal Appendage	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
BRD-K96263742_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebellar Vermis Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52473
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36287933_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740571
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1955
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04044
Perturb_15272_KD_Tardbp_SRP254218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.31732
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
NFE2L2_02_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60407
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33688
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918765
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S32W-1626-SM-4AD6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0577
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.181256
JAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555692
BRD-K74148702_curcumin_MCF7_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08742
BRD-K38980456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25687
CYLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502431
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98492
PMC6070353__F2	PFOCR Pathway Figure Associations 2024	1.0	null
abnormal renal tubule morphology	MPO Gene-Phenotype Associations	1.0	null
Malar Flattening	DisGeNET Gene-Disease Associations	1.0	null
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Leber congenital amaurosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25437
Miller-Dieker lissencephaly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988866
Organelle membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
Tented Upper Lip Vermilion	DisGeNET Gene-Phenotype Associations	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K13646352_PKC-412_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
METTL24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052803
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37475
Perturb_4317_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.09981
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870199
aplasia/hypoplasia of the extremities	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499837
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40496
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A07029265_IPRATROPIUM BROMIDE_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3172
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09828
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ZNF358_ZNF358	Rummagene Transcription Factor Associations 2026	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4856
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26006
BRD-K08799216_pelitinib_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208701
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974326
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DNM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00280075
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34474
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56596360_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23411
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64615
KMS20	DepMap CRISPR Gene Dependency	1.0	2.31526
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16318
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149010_0_v_6_dars2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38664
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78761
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55862
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49835
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54272776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44075
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.015509
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87191
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.20071
STAT2_02_18	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60039
Perturb_12683_KD_circEZH2_SRP388087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.064
FOXA2	ENCODE Transcription Factor Targets	1.0	null
MCF7	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59879
abnormal axial skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6384
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16057
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52936
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13125
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37751
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25425
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33049
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49972
RYK	Pathway Commons Protein-Protein Interactions	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88445
GSE199189_1_v_0_creld2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Subcortical band heterotopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.546
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94405
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60605
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	2.04775
MCUR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00371034
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3979
GATA5_KO_GDS4809_170_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Rucaparib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.54
SIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533774
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.70372
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88647
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC2882122__F4	PFOCR Pathway Figure Associations 2024	1.0	null
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36398
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal endochondral bone ossification	MGI Mouse Phenotype Associations 2023	1.0	null
Microlissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PDE4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484332
BRD-K19724398_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.827169
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5803
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06541
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6354
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8637_KO_Arid1a_SRP312002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.03094
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47645
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A36471396_Biperiden hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78681155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26861
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19616
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
6603-0104	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95814
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5267
H3K36me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473132
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
micrognathia	HPO Gene-Disease Associations	1.0	null
DGKG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615106
binding	GO Molecular Function Annotations 2015	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09182
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-0.952995
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00506
short sternum	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17095
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89285
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79037
BRD-K36529613_P0030_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15152
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48018
CR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553407
PLOD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00431035
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06922
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50446
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.75768
NOMO1	DepMap CRISPR Gene Dependency	1.0	5.69612
PBX3	ENCODE Transcription Factor Targets	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993832
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09121
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15576
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Actin filament bundle of actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
IGFBP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00737922
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.41294
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8018_KO_PXR_SRP257678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kinociliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03278
P38D	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873874
single-organism process	GO Biological Process Annotations 2015	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal scala media morphology	MPO Gene-Phenotype Associations	1.0	null
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421325
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58569
BRD-K17743125_S1085_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10339
MAP3K6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514538
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70108
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659471
BRD-K92359570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38465
SMAD4	ChEA Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19785
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13195
hsa-miR-520a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Perturb_1166_KD_ETV6_ERP128093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
aplasia/hypoplasia of the corpus callosum	HPO Gene-Disease Associations	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50468
JHOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.58346
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.7782
PMC3534415-1755-8794-5-26-S1.pdf-4-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943589
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31472
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.276
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
DNLZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610768
PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Up-regulated-Supplementary_Table_S2_Up-reguated_genes_expression_in_MESP1_positive_cells_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
VRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00449455
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63091
Perturb_9713_KO_Miwi/Mili/Miwi2_SRP036148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.10519
BRD-K25147028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24759
non-myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
abnormal intestine morphology	MGI Mouse Phenotype Associations 2023	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02244
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	220.843
van maldergem syndrome 1	OMIM Gene-Disease Associations	1.0	null
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73438
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88032
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49573
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testicular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
Hippo signaling pathway - multiple species	KEGG Pathways 2026	1.0	null
astrocytes	BioGPS Cell Line Gene Expression Profiles	1.0	1.20792
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055757
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360409
BRD-A61470182_N-FORMYLMETHIONYLALANINE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93064
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51955
clinical modifier	HPO Gene-Disease Associations	1.0	null
neuronal	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
METAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0036987
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09202
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70485
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03814
URB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00680794
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
finger syndactyly	HPO Gene-Disease Associations	1.0	null
mRNA_DPPA5A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BCAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00881357
estradiol_homo sapiens_gpl570_gse29881	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1015
STK33	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-A41451487_PK-11195_A375_24.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10054
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.046
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888042
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	246.436
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_upregulated-Genes_upregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889654
BRD-A19037878_trichostatin A_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82286
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933306
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00423
BRD-K09367542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27792
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60391
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283215
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15538
BRD-K18245187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37136
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.55246
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070125
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98705_1_v_0_mdm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9585487-NIHMS1838959-supplement-4.xlsx-Downregulated-Table_S3_FOXC1_regulated_genes_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
hsa-miR-142-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
LXR-623	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68407
BRD-K90475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39179
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0045547
abnormality of globe location	HPO Gene-Disease Associations	1.0	null
L-165041	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16249
Nephronophthisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32459
Extrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41648
SUGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627543
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62773
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967548
anal atresia	HPO Gene-Disease Associations	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38504
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51416
cochlea development	GO Biological Process Annotations 2015	1.0	null
Cytoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	221.895
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08631
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957668
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24938
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954329
LEFTY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460594
Tetralogy of Fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18752
BRD-A13983189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0168
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1456
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18068
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60452
Pontocerebellar hypoplasia type 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91861
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.12143
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874707
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11921
BRD-K24132293_piperlongumine (HPLC)_SW480_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47367
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18072
PID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486411
hsa-miR-4726-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.2844
LS-1034	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5559
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
abnormal thoracic vertebrae morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90664
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877821
BAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00426809
BRD-K53665750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00509
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965634
PMC11133462-41467_2024_47218_MOESM5_ESM.xlsx-IL-10_SBNO2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.44273
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09983
hsa-miR-3155b	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95663
LRRN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628607
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99134
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20658
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22889
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13726
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43001
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
CAKUT	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1512
KMS18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58963
abnormal kidney development	MGI Mouse Phenotype Associations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20129
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15466
NCAPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429286
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36587
C7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508706
BRD-K95443593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12629
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05876
WB-4101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40904
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34997
SMCO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00708276
NALM6	DepMap CRISPR Gene Dependency	1.0	5.03373
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08159
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282837
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HTR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543223
BRD-K50417536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03011
Perturb_3241_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.5982
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07346
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.467
skin	HPA Tissue Protein Expression Profiles	-1.0	-0.75363
short fourth metatarsal	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46385
PMC4450212__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K14163107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74994
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3943
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01308
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.583
KCNJ10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651237
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03538
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19086
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01049
MARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064147
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67145
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
abnormal skeleton physiology	MPO Gene-Phenotype Associations	1.0	null
GCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582019
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84951
BRD-K24132293_piperlongumine (HPLC)_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47834
PRKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589306
STK36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757134
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cholesteatoma tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Tacrolimus	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
Mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
FOLH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00879952
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.71124
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05051
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.922682
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48063
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892371
morphogenesis of a branching epithelium	GO Biological Process Annotations 2015	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02708799_GSK-1059615_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89726
SCN7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754682
CRCGN015_MCF10A_48H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2251
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13675
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13748
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24132293_piperlongumine (HPLC)_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965102
BRD-A22152765_Tridihexethyl chloride_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13897
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921985
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24212
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
KCNK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536738
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
MTNR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567747
BRD-K87990216_Piretanide_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ntera2cloned1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3562
SR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
BRD-A94377914_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46369
abnormal thoracic cage morphology	MPO Gene-Phenotype Associations	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76489
SLC2A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658157
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880738
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966358
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950422
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29702
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPHN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00779111
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68476
NEDD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519903
BRD-K08154407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.1677
BRD-K63800697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40331
hypoplastic facial bones	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.952199
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27619
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14318
aplasia/hypoplasia involving the metacarpal bones	HPO Gene-Disease Associations	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.96803
Osteopenia	DisGeNET Gene-Disease Associations	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865546
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08367
WNK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635473
BRD-K04819729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6171
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75133
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.85995
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285201
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01759041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67879
SCN2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065651
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Growth Delay	DisGeNET Gene-Phenotype Associations	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56452
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.00203
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.15684
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.312936
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12058
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70675
hsa-miR-4697-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-680N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53672
Perturb_552_KD_EWSR1/EWSR1FLI1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.9043
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826876
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hypoplasia of the maxilla	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A_48H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68014
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3176
wide anterior fontanel	HPO Gene-Disease Associations	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal spine curvature	MGI Mouse Phenotype Associations 2023	1.0	null
Wnt signaling pathway	PANTHER Pathways	1.0	null
CHD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045058
Perturb_13115_KO_Foxm1_SRP194062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.32563
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70274
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.088023
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06983
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81608755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73456
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K68731395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46847
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5834-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01948
PCYT1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642539
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16691
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6625
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4594
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34865
BRD-K67010098_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.90918
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Epineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77419
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NTSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052334
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971841
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01028
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36899
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33260002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14729
Developmental and epileptic encephalopathy 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Noonan syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35904
FAM20C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733177
LGALS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00411228
GNGT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500061
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21722
abnormality of the auditory canal	HPO Gene-Disease Associations	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300346
PMC4905481-oncotarget-07-11397-s003.xlsx-CtBP1_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the cerebral subcortex	HPO Gene-Disease Associations	1.0	null
BRD-K49294207_BIBU 1361 dihydrochloride_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91037
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924399
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15513
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40659
BRD-K40724407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21705
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Macular degeneration_Fibroblast_GSE1719	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.47047
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08218
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11378
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.5461
A172	BioGPS Cell Line Gene Expression Profiles	1.0	0.830554
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28026
Perturb_9025_KD_NR4A3_SRP324495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.82446
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26048
TE-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415728
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5901-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13678_KD_DHX9_SRP018815	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0067
PRDX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551336
Heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	299.133
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30627
Clinodactyly	DisGeNET Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	1.0	1.39769
mitral valve formation	GO Biological Process Annotations 2025	1.0	null
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92395
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889464
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
oxybutynin-3168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.39127
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28828
anorectal anomaly	HPO Gene-Disease Associations	1.0	null
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848665
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994443
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14943
KMRC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.3987
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
digestive tract development	GO Biological Process Annotations 2015	1.0	null
RARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634465
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
BRD-K97869597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10083
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84293
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673571
NCIH1048	CCLE Cell Line Gene Expression Profiles	1.0	1.46812
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6675
MYLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00852787
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31324
SLC66A1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525156
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570251
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04586
perinatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LIFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520436
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52796
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.0019
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163052,GSE163198_5_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNMT3L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00418618
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38411
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55968
BRD-K41925105_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584471
SUCLA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557609
DOK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842349
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90837
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08508
encoding	GeneRIF Biological Term Annotations	1.0	null
KDM1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647623
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15596
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.650869
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.64461
Glial cell_Skin_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952643
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HB1119	DepMap CRISPR Gene Dependency	1.0	2.55885
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.964
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41452
monomethylarsonous acid	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.922682
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.276
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38177
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
positional foot deformity	HPO Gene-Disease Associations	1.0	null
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88204
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9998
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3285
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7849
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
MEP1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611883
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09828
RHPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447098
KDM5A	ENCODE Transcription Factor Targets	1.0	null
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.90414
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-2_E2F1-Gene_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Nasal Bridge Wide	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970961
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604586
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STK38L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636671
ACKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634214
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paroxetine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.04
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6070353__F2	PFOCR Pathway Figure Associations 2023	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481598
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.61335
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
X-linked cardiac valvular dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
KALRN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598052
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88405
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.29168
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056335
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947018
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07054
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52448
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DHFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00439433
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48962
PRKCI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056061
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3442_KO_Mll4_SRP101279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29966
CHRNE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497717
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Table_S6_Overlap_of_differentially_expressed_genes_in_Tg_HSP_EWS-FLI1_embryos_and_human_EWS-FLI1_signature_from_Smith_et_al_2006_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.40749
SOX17	JASPAR Predicted Transcription Factor Targets	1.0	null
SNU324	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53717
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47839
ASXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00395583
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18187
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19143
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MFSD13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00708961
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.49114
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91528
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64118
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
LN428	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15487
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1732
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32712
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32936
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19338
BRD-K60898929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51257
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18711
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901032
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06361
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IFNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647494
GTEX-OIZG-0926-SM-3LK5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17636
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42553
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273959
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15855_KD_KDM3A_SRP270313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.2924
CXCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564992
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Periventricular Nodular Heterotopia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28167
Perturb_12657_KD_Yap1/Wwtr1_SRP212072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42695
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957668
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ES8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947009
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950389
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human - Fetal Development - L2 - Adrenal-Schwann cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC4677515__F1	PFOCR Pathway Figure Associations 2024	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0078
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040907
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
abnormal sternum morphology	MPO Gene-Phenotype Associations	1.0	null
mitral valve morphogenesis	GO Biological Process Annotations 2025	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A32595718_CVF-CSC-7 BRD-A32595718_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A87N-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cyclopenthiazide-4229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03814
LIPF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542045
Heart sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
epithelium development	GO Biological Process Annotations 2015	1.0	null
BRD-K81418486_vorinostat_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42415
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
abnormal lung morphology	MPO Gene-Phenotype Associations	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.723755
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04218
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Aortic valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945201
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00814959
BRD-K45904718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0805
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGW	GDSC Cell Line Gene Expression Profiles	1.0	2.9235
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40991
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07236
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75699
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64574
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.684849
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypoplastic right heart syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
GCSH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664421
narcolepsy	GWASdb SNP-Disease Associations	1.0	2.08953
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12636
complete perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957993
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62468
etiocholanolone-4298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Disease Associations	1.0	0.787916
NSD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00690536
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.943105
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.275
NCIH661	Achilles Cell Line Gene Essentiality Profiles	1.0	1.44918
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0826-SM-4LMIH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54024
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Postlarva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
bromopride-4741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29705
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77949
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4524
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051892
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.174
ossification	GO Biological Process Annotations 2015	1.0	null
GTEX-TKQ1-0526-SM-4DXTG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14369
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.451606
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.371
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062529
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NLRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694335
misalignment of teeth	HPO Gene-Disease Associations	1.0	null
abnormal pectoral girdle bone morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-A36275421_MW-ras12_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
conductive hearing impairment	HPO Gene-Disease Associations	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.5838
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
DB-21-FY25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246282
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.39183
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03597
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17327
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93321
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
STK32C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598148
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20992
SW872	GDSC Cell Line Gene Expression Profiles	1.0	1.77483
DIFI	DepMap CRISPR Gene Dependency	1.0	2.27516
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39476
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16395
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28902
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	164.312
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5956
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.123849
BRD-A93436351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15793
abnormality of the thorax	HPO Gene-Disease Associations	1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00345
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.95286
Perturb_14779_KO_PGRB_SRP309208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.45006
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42719
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02502
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.751382
BMF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00840036
Vatalanib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880971
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43851
abnormal spine curvature	MPO Gene-Phenotype Associations	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51696
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.33675
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.251032
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
BRD-K59049030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55753
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0321
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Rh-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Mitral Valve Insufficiency	DisGeNET Gene-Phenotype Associations	1.0	null
TCIRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668005
PMC12079334-ADVS-12-2501734-s002.pdf-114-ENSG00000177030_DEAF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66105
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249156
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	419.455
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31979
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01024
Ebstein anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18689
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995787
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68401
developmental disorder of mental health	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
SUFU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541821
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9844011-media-1.pdf-6-KLF12_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846581
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2519
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706299
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849262
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08646
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K94616959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12706
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7464
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79322550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50474
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	1.02819
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF141	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467199
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20742498_RS 39604 hydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.103145
BRD-K79145749_Dibenzepine hydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56904
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00648
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07056
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48106
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8655_KO_ESRRA/ESRRG_SRP304242	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APBA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049175
BRD-K61912055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.051
BRD-K15409150_PENFLURIDOL_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	221.352
abnormal urinary system development	MPO Gene-Phenotype Associations	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64131
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69863
ADGRE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607122
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTNND2	Pathway Commons Protein-Protein Interactions	1.0	null
STAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609152
TMEM175	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795341
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92193
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51961
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.34592
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippo signaling	GO Biological Process Annotations 2023	1.0	null
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16233
Perturb_13058_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82639
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitral valve insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.093
PLA2G2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508367
hsa-miR-4535	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22479
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
F8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613618
BRD-K43468685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20718
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.52942
PBXIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545355
PIP5K1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00872601
AVPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613184
S100A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568795
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63697
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.922682
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29639
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
HSD17B8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707687
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34922
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7264
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00819
BRD-K45245001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69199
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08754
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	2.28604
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
atrioventricular valve formation	GO Biological Process Annotations 2025	1.0	null
hsa-miR-612	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946173
BRD-K12239796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00805
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.41829
PILRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480409
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09498
Pseudopterygium	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
osteopenia	HPO Gene-Disease Associations	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	0.927242
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.055478
SPNS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550241
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.396
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7787
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1666
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.922682
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34443
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930233
BRD-K49865102_PD-0325901_HA1E_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02979518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25009
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.511765
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26018
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0844
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.143914
HCC1395	DepMap CRISPR Gene Dependency	1.0	3.57325
ULK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0075431
abnormality of the vertebral column	HPO Gene-Disease Associations	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03544
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99614
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839895
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25596
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36776
MREG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0074834
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2935
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19679
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17437
BRD-K49371609_528116.cdx_OV7_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291309
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.932812
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09991
PRMT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496828
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25261
K562	DepMap CRISPR Gene Dependency	1.0	3.58899
KYAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00839112
CERT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536591
coronary artery disease	GAD Gene-Disease Associations	1.0	null
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55952
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6106
Perturb_18014_KO_miR19a/miR19b1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41643
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064409
SRF_KO_GDS3732_148_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83085
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620831
BRD-A45889380_QUINACRINE HYDROCHLORIDE_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01413
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
VSIG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573267
INO80	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727863
TSPAN14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577521
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02721
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50236
Perturb_16492_KO_Traf3_SRP260017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.11717
BRD-K71537757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13369
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0137
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20816
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10383
BRD-K11928012_NCGC00182913-03_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FHIP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045846
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Periventricular Gray Matter Heterotopia	DisGeNET Gene-Disease Associations	1.0	null
B2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058865
DOCK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730676
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24061
BRD-K47983010_BX-795_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	251.655
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90177
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12281
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal orientation of cochlear hair cell stereociliary bundles	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10981
disease	GWASdb SNP-Disease Associations	1.0	0.050739
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76653
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57053
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
FCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479405
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of digit	HPO Gene-Disease Associations	1.0	null
small kidney	MPO Gene-Phenotype Associations	1.0	null
BRD-K54742099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43658
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0947
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22988
aplasia/hypoplasia involving bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.9951
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64006
BRD-K24132293_piperlongumine (HPLC)_NCIH596_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80775
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0674
Basal body patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
PCSK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536936
BRD-K21546432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29229
aplasia/hypoplasia involving bones of the thorax	HPO Gene-Disease Associations	1.0	null
Carprofen	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
CFAP46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0066634
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52954
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of neuronal migration	HPO Gene-Disease Associations	1.0	null
MAPKAPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00445327
HRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472947
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14716
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849886
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042793
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH5	DepMap CRISPR Gene Dependency	1.0	3.67202
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.14508
abnormal cochlear hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28047
dilated kidney collecting duct	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
BRD-K02283807_GR 32191 hydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2025	1.0	null
short 4th metacarpal	HPO Gene-Disease Associations	1.0	null
BRD-K18724229_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00615600_AG14361_MCF7_6.0_h_25.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08161
BRD-A70649075_SULCONAZOLE NITRATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
SW403	DepMap CRISPR Gene Dependency	1.0	2.78488
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28598
DPM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00708388
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20834
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
CCK81	DepMap CRISPR Gene Dependency	1.0	6.17671
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68279
BRD-K79264000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77398
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56452
ATP9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497534
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
BRD-K00910650_NCGC00242335-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630659
embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.797708
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54639
SDHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678268
hsa-miR-492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9418
STAT3	ENCODE Transcription Factor Targets	1.0	null
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02031
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24689
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
BCL3	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54042
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27657
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35499
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00298
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28075
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882909
Pars tuberalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06569345_HG-5-88-01_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
BRD-K13261168_LY-163,502_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17532
BRD-K13049116_BMS-754807_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MRS 1754	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40823
BRD-A46950333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95018
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02035
BRD-K14258088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53849
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09054
short palpebral fissure	HPO Gene-Disease Associations	1.0	null
hsa-miR-24	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
TXNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582486
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Syndactyly	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10423
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69742
SLC22A23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00808093
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18204
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865353
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01747
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12674
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46936325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83999
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
NCI-H1048	GDSC Cell Line Gene Expression Profiles	1.0	1.98062
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Midface Retrusion	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-2861	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
MAPK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00426262
neurogenesis	GO Biological Process Annotations 2023	1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16372
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601465
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48533
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3834
PKDCC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645003
PMC7204122-4623107.f1.docx-6-CHAMP1_CHAMP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A50837272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60658
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960553
VMRCLCP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.85626
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14722
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43514
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69351
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58355
abnormal lung size	MPO Gene-Phenotype Associations	1.0	null
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16409
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92669
SPI1	ChEA Transcription Factor Targets	1.0	null
BRD-K07667606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63509
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.984817
ITGB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614494
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12067
BRD-K81651477_Parthenolide_H1299_6.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal sensory neuron morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K37130586_Olopatadine hydrochloride_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47543
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	259.288
mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCDC71	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00474609
MRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054737
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59164
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
16109776-TableS1	GeneSigDB Published Gene Signatures	1.0	null
abnormal morphology of bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29966
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472542
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07615
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886735
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939448
PTPRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483602
BRD-K38347298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30421
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.077792
Perturb_10604_KO_Ncor1_SRP216477	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93842
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5122
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9706722__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
KCNJ4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00651682
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868755
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8195-01A-31R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50398167_MECLOFENAMATE SODIUM_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Cholesteatoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826639
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2512
SH3GL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00832468
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IFNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068707
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905742
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A79465854_auranofin_SW948_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal vertebrae morphology	MPO Gene-Phenotype Associations	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78985
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29034
BRD-K17953061_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46595
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.93356
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cadherin conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K11297155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20761
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09963
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32435
Human - Pancreas - L1 - schwann	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Feeding Difficulties	DisGeNET Gene-Phenotype Associations	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30428
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23953
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524981
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
Perturb_16432_OE_E2f4_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.7825
NKX2-6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617579
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889973
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.572
abnormal heart morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963576
skin dimples	HPO Gene-Disease Associations	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.03107
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
HIVEP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526539
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.7223
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5351
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Short 4Th Metacarpal	DisGeNET Gene-Phenotype Associations	1.0	null
RARA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555515
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
humans	GeneRIF Biological Term Annotations	1.0	null
HIVEP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575238
ZNF641	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
BRD-K95018971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33558
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955587
abnormal cochlear sensory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal interatrial septum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Odanacatib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.61
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64811593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40427
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24023
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18364
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287016
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12862
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32751
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2856
KDM4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524207
RNF24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102312
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92338
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892326
JUND	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691634
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64268
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26821
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35129
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15283
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967399
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Severe Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871975
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76924
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59626557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46443
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833297
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal neural tube morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_WT_KLF4-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02815
SIPA1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532938
ULK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467393
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50031
15257931-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01634
BRD-K25280080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69604
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K56351525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85186
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.503
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33661
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26429
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT20H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619629
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474646
GSE190761_0_v_1_samd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9601
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36152
displacement of the external urethral meatus	HPO Gene-Disease Associations	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEDD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00444307
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158738_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal tail morphology	MPO Gene-Phenotype Associations	1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21182
wide cranial sutures	HPO Gene-Disease Associations	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22233
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12907
malar flattening	HPO Gene-Disease Associations	1.0	null
BRD-K64606589_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80753
Atellite glial cell_Dorsal root ganglia_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861155
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10176267_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48688
BRD-K56751279_Y-39983_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
STAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463734
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10099
Autosomal recessive polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542929
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10406
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7729
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LGALS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99239
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03153
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16525
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ morphogenesis	GO Biological Process Annotations 2015	1.0	null
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
SRC	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
non-gestational choriocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04992
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00479
SSTR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435641
Hypertropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
sacral dimple	HPO Gene-Disease Associations	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30459
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01041
MTAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662977
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10764
FRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730754
Infertility, Female	CTD Gene-Disease Associations	1.0	1.05237
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACHN	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.58657
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7062_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.63561
KCNMB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603055
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25607
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04067194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44915
IMR32	CCLE Cell Line Gene Expression Profiles	1.0	2.33167
Acquired Camptodactyly	DisGeNET Gene-Disease Associations	1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_15709_KD_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.769
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82454
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral Ventriculomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895762
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Human - Kidney - L2 - Schwann / Neural	HuBMAP Azimuth Cell Type Annotations	1.0	null
BRD-K04631545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92748
BRD-K49325049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16543
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90859
cadherin binding	GO Molecular Function Annotations 2023	1.0	null
hsa-miR-759	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Tadalafil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.66
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974939
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biological adhesion	GO Biological Process Annotations 2015	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23942
cinchophen	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41383
BRD-K03829970_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01555
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39908
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937352
PMC5857600__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1957
Mitral Valve Prolapse	DisGeNET Gene-Disease Associations	1.0	null
Human - Fetal Development - L2 - Pancreas-ENS glia	HuBMAP Azimuth Cell Type Annotations	1.0	null
Atresia	DisGeNET Gene-Disease Associations	1.0	null
Perturb_4293_KO_Tbc1d4_SRP374413	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9413
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.05328
BRD-K76008396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59015
postnatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
TRPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706152
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54971
AIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490964
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955362
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K18724229_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KIF3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503541
MYH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633277
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	5.64437
SMZ1	DepMap CRISPR Gene Dependency	1.0	5.76749
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04808
BRD-K49461735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90322
Sacral Dimple	DisGeNET Gene-Phenotype Associations	1.0	null
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
Perturb_8634_KO_Htr6_SRP223109	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.21721
EW-11	GDSC Cell Line Gene Expression Profiles	1.0	1.68288
BRD-K35960502_NICLOSAMIDE_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pulmonary Stenosis	DisGeNET Gene-Disease Associations	1.0	null
PF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00844699
Sertoli cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K79072801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44157
BRD-K28296557_Akt inhibitor IV_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6474-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901071
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831117
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40688
sulfanilamide-4474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
BMPR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456921
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.83321
Human - Kidney - L3 - Schwann / Neural	HuBMAP Azimuth Cell Type Annotations	1.0	null
Subventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
renal hypoplasia	HPO Gene-Disease Associations	1.0	null
cell junction assembly	GO Biological Process Annotations 2023	1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.94021
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96104
Epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205357
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59324
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.762
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.293
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.383637
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17798
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51271
BRD-K60483981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68297
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03551
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5811
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75292
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14479
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-A69927616_isradipine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97321
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
BRD-K89853033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45216
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_3_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94057
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39945
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
PIK3C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671117
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35873
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32264
Mitral valve prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.707
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
RBM47	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671579
BRD-K79816111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03654
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32477
BRD-K55209210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22969
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838233
FCRLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482461
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GATA5_KO_GSE47425_50_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892495
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.31476
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49394
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.931
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24337237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02824
Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RC-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RENBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628292
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94126
REST	ChEA Transcription Factor Targets	1.0	null
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13791
Perturb_9740_KO_Kcnj11_SRP279345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.25514
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2178_KO_Dnmt3a_SRP234989	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.85733
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.72471
PLA2G2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0090412
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96577
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S10_DGEA_IKZF1-Supplemental_Table_10_Differentially_expressed_genes_between_IKZF1_and_all_other_subcluster_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
CAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061231
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12371
Dilated Ventricles (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25651
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CURI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.261
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
18593951-TableS3	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60872
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37894
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.989884
HMMR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541277
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50823
SLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637122
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881282
BRD-K56700933_PEITC_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97969
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67145
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
TAS2R60	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608391
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995719
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5517-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17736_KO_Ikkb_SRP315113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.0874
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74386
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05715
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873429
BRD-K91137832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0497
HSC4	DepMap CRISPR Gene Dependency	1.0	4.08759
GATA2	ChEA Transcription Factor Targets	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0116
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887245
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29301
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07237
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	0.684849
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Small Ears	DisGeNET Gene-Disease Associations	1.0	null
ARFGEF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599695
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11861
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31107
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.42803
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43912
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949562
Cytoproct	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12605
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95228
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFEMP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695769
BRD-K43535770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46107
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903636
abnormal kidney size	MPO Gene-Phenotype Associations	1.0	null
BRD-K42995703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45905
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315059
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02995
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74467
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.920772
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.986163
NB17	DepMap CRISPR Gene Dependency	1.0	3.2655
catenin complex	GO Cellular Component Annotations 2025	1.0	null
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurilemoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876112
LN235	DepMap CRISPR Gene Dependency	1.0	2.29194
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785068
PNKP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00711218
CDKN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675645
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10943
BRD-K48235506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38704
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837493
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68119
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31905
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50106
includes	GeneRIF Biological Term Annotations	1.0	null
BRD-K74148702_curcumin_A375_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIRT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515188
Carpenter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79279
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47908
TT2609C02	DepMap CRISPR Gene Dependency	1.0	2.57411
Pituitary Stalk Interruption Syndrome	DisGeNET Gene-Disease Associations	1.0	null
dilated kidney collecting duct	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04402
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1876	CCLE Cell Line Gene Expression Profiles	1.0	1.78059
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93008833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24099
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096718
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4190_KO_Dnmt3a_SRP300442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.0696
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BLTP3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522044
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72336
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15534
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16288
FGB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719867
PLA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613882
BRD-K66254772_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTHFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00468855
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0837
LILRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655299
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Perturb_16648_KO_Tardbp_SRP201975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.66365
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895061
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15239
TREML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552201
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
joint laxity	HPO Gene-Disease Associations	1.0	null
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37225
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.21062
WARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515955
LS513	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.84307
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22111
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TESPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00792146
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01105
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38221
DPYD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593817
TIMD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673597
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pseudopalisading cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
Short Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
MAPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600724
downturned corners of mouth	HPO Gene-Disease Associations	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3619
KLRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653904
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IGSF10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00744945
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997705
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11241
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BxPC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.90203
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_351_OE_CD274_SRP287831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.8928
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873486
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31616
Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPREB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552761
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01408
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06553
RAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575045
OV7	DepMap CRISPR Gene Dependency	1.0	2.83288
hearing abnormality	HPO Gene-Disease Associations	1.0	null
BRD-K81209159_HERNIARIN_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.72581
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41045
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60404
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975742
anteriorly placed anus	HPO Gene-Disease Associations	1.0	null
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25333
renal hypoplasia/aplasia	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7925-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26079
FCGR3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620023
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924221
Human - Fetal Development - L2 - Stomach-ENS glia	HuBMAP Azimuth Cell Type Annotations	1.0	null
abnormal cochlear labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830917
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16853
wide sternum	MPO Gene-Phenotype Associations	1.0	null
Perturb_7491_KD_MLLT3_SRP174861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499237
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11373733-ABR-13-34_Suppl1.pdf-61-FOXO6_FOXO6	Rummagene Transcription Factor Associations 2026	1.0	null
oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.24824
lung	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
EZH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471278
VCAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694456
CXADR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691418
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22068
SLC41A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0079533
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919439
BRD-K92193792_Nizatidine_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HEC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34486
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05393
CXCL12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429222
cadherin binding	GO Molecular Function Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49105
BRD-K67847053_Guanabenz acetate_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Van Maldergem Wetzburger Verloes Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.29225
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
BRD-K69269415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24278
LN382	CCLE Cell Line Gene Expression Profiles	1.0	1.52401
KP-N-YN	GDSC Cell Line Gene Expression Profiles	1.0	1.46041
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAZ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522549
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.256989
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2909-03A-01T-0744-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABT-199	DeepCoverMOA Drug Mechanisms of Action	1.0	0.98
IFI30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055949
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237988
ASS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0035145
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945733
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52164
Human - Fetal Development - L1 - Schwann cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
BRD-K76734722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.089
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.138
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4960540-srep30217-s5.xls-VD_metabolism-V_VDR_Q3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
hypospadias	HPO Gene-Disease Associations	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K63569039_NCGC00012508-02_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73116
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18805
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36136
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
curly tail	MPO Gene-Phenotype Associations	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
G6PC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623959
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56864
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44022
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the anterior fontanelle	HPO Gene-Disease Associations	1.0	null
Mitral Valve Prolapse Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03214
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371406
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3232
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.828614
BRD-K24156250_NCGC00182393-01_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_11186_KO_Gdown1_SRP244620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59146
MST1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671119
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33229
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49029
Lymphedema	DisGeNET Gene-Disease Associations	1.0	null
Endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
BRD-K03549232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0722
Dysmorphic Facies	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14099
ABCA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641109
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75907
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K26664453_-666_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58847
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8721
Perturb_15238_KD_TINCR_SRP082178	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0672
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863643
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.32132
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
INT-747	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
Perturb_13124_KO_Taf4_SRP022250	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC4684962__F5	PFOCR Pathway Figure Associations 2023	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835732
GSE184892_4_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853367
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ROBO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497399
Hypertension	CTD Gene-Disease Associations	1.0	1.09366
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957668
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39004
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846798
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874707
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437372
BRD-K32170456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15451
BRD-K35462787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23469
large fontanelles	HPO Gene-Disease Associations	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0085
BRD-K44921612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16884
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPMI-8226	GDSC Cell Line Gene Expression Profiles	-1.0	-2.34425
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.701
FOXP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469711
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5677
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.34096
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33807
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4637
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10484
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.45734
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_4_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A61778798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33462
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K95338817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03345
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.871248
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19251
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07347
mitral valve prolapse	MGI Mouse Phenotype Associations 2023	1.0	null
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31474
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02306
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823919
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.246
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07177
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0004
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977584
Perturb_15865_KD_LSD1_SRP228812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.90263
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839645
BRD-K35240878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9706
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55041
GTEX-XAJ8-0326-SM-47JYI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07062
C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066529
km3	HPA Cell Line Gene Expression Profiles	1.0	1.37289
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
hsa-miR-4508	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
BRD-A72703248_SKF 96365 hydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12579
TBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766706
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ntera2	HPA Cell Line Gene Expression Profiles	1.0	0.86383
BRD-K02822062_CT-200783_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962134
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00901
BRD-K49132774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4291
CTCF	ENCODE Transcription Factor Targets	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52819
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
CDC25A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00412559
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864858
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12597_KD_Gatad2b_SRP366371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.84977
abnormal ureteric bud morphology	MPO Gene-Phenotype Associations	1.0	null
Atrioventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923322
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02799
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53629
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962015
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15898
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21324
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03237
mitral valve formation	GO Biological Process Annotations 2023	1.0	null
GSTP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0040163
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrostomy Tube Feeding In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
Extrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K13566078_BMS-345541_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tube development	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946533
RHAG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567293
Cadherin-like	InterPro Predicted Protein Domain Annotations	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1047
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0727
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16305
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.933
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50539
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.824747
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65861
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81129
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40959
SLC2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00381994
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066445
abnormal hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20615
benzylpenicillin-6155	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23888
BRD-K74399971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57577
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
epithelial-myoepithelial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
YAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444719
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16591
r9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
FYN	Pathway Commons Protein-Protein Interactions	1.0	null
IFI6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045283
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal heart atrium morphology	MPO Gene-Phenotype Associations	1.0	null
RASGRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561051
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12067
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354949
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal cochlea morphology	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9587
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93853
ITPR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0079701
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302252
TMEM71	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00994906
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K78603273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26154
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EOMES	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056644
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00670685
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PROZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00397129
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283351
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
OR52N4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557882
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K46561246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5195
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049338
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-ISL1-Unnamed_3_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845177
BRD-K24025166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05292
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21565985_XYLAZINE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
yap1_18413746_mcf10a_gof_human_gpl570_gds3220	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.900295
GLYATL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745742
BRD-A89907244_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898448
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
malar anomaly	HPO Gene-Disease Associations	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78154
BRD-K14914284_NCGC00187898-02_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14942405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70511
BRSK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00882666
PMC4684962__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00843
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80817
BRD-K58220038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07779
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23049
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9116
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07663
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infective endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.43379
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K60484506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37982
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21268
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15534
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2015	1.0	null
PINK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00812594
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43631
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76455
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49705
adherens junction organization	GO Biological Process Annotations 2023	1.0	null
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K34747076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30404
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91993
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52048
Malocclusion	DisGeNET Gene-Disease Associations	1.0	null
MAP3K21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537696
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18713
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Neurological pain disorder_Dorsal Root Ganglia_GSE15041	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.01147
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.995168
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934486
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058572
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
CD79B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673457
BRD-K98968761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31726
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95411
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39544
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10465
NEK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600106
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12606
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Simpson-Golabi-Behmel syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836107
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S4-Supplemental_Table_S4_Genes_commonly_upregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.916959
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066231
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0085
CEBPB	ENCODE Transcription Factor Targets	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
hsa-miR-4314	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFNA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0101255
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
PRPS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492295
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10375
FYB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551138
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3952
BRD-K88378636_withaferin-a_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	320.516
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03803
PTEN_01_302	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59635
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AIF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546225
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KANSL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629437
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.401
UBB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00421669
BRD-K57251296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31001
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52274
Blepharophimosis	DisGeNET Gene-Disease Associations	1.0	null
Melanocytes and Schwann cell_Skin_Human	CellMarker Gene-Cell Type Associations	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM793	DepMap CRISPR Gene Dependency	1.0	2.31071
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.97125
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
BRD-K73402542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51902
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DMPK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527439
Human - Heart - L2 - Neuronal	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
growth delay	HPO Gene-Disease Associations	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5015
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.33675
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.49371
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05183
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82482
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31501
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10633
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Megacolon	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.946588
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323208
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87768
Perturb_5851_KD_SUPT4H1_SRP076722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49947
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02060635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86746
BRD-K16214172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32609
Perturb_2858_Mut_BRAF_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TALL1	CCLE Cell Line Gene Expression Profiles	1.0	1.36485
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP20A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488089
PFSK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06114
PMC7857731-elife-63093-supp5.xlsx-ECMdegsTCGAMITFlowvs_high-Differentially_expressed_ECM_genes_in_MITFlow_vs_MITF_high_tumours-SKCM_TCGA_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
RRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688252
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854682
TMEM163	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675111
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29761
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22062
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.940653
ANG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590449
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52955
BRD-K70577657_H-9 dihydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.930506
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9591
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	1.83527
SKNDZ	CCLE Cell Line Gene Expression Profiles	1.0	1.71639
Brachydactyly type B1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
cell-cell junction	GO Cellular Component Annotations 2023	1.0	null
BRD-K39710695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09537
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21551
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90643
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1726
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40103182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01218
BRD-K76197651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36932
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.7883
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97309
BRD-K37956279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99843
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04729
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09987
Lung adenocarcinoma_LUAD_TCGA-44-6777-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21773
schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413151
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11866
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Rifampicin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568493
aplasia/hypoplasia involving bones of the hand	HPO Gene-Disease Associations	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87997
epicanthus	HPO Gene-Disease Associations	1.0	null
abnormality of the fourth metatarsal bone	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134375_3_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TM4SF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00752464
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844668
Skeletal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K37282009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46226
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18417
MMACHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689696
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911975
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93477
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61159
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45649
BRD-K01166365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63697
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57053
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051325
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3108
abnormality of the midface	HPO Gene-Disease Associations	1.0	null
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25831
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.45264
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984259
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6019-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
G6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658343
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61523
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26156
BRD-K43381631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86638
abnormal kidney development	MPO Gene-Phenotype Associations	1.0	null
APOE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402238
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924399
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08549
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21413
Perturb_14501_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.4218
MCF7	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01259
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08581
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83051
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nicotine addiction_Ganglioneuroblastoma_GSE11208	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.13233
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35685
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874707
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41916
MAST3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00771079
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67445247_Flurofamide_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.326829
hypersomnia	GWASdb SNP-Phenotype Associations	1.0	2.06154
hypoplasia of the corpus callosum	HPO Gene-Disease Associations	1.0	null
Irregular Dentition	DisGeNET Gene-Phenotype Associations	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04064
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53041
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72890304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22638
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50946
Perturb_17205_KO_miR17/miR20a/miR92a1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.59434
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58338
OGT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00836487
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
RERFLCAI	CCLE Cell Line Gene CNV Profiles	1.0	1.39467
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.86211
abnormal heart septum morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4575
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01716
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07767
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.23722
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25668
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95272
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.7761
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.95526
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11465
TNFRSF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541773
GSE196699_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
UNCX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113657
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
scoliosis	HPO Gene-Disease Associations	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal orientation of cochlear hair cell stereociliary bundles	MPO Gene-Phenotype Associations	1.0	null
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1315
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31378
ATP1B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829261
STK26	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545725
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital Hypoplasia Of Kidney	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
abnormality of the forehead	HPO Gene-Disease Associations	1.0	null
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BCB000040-7488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30221
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC12A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603778
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89865
cutaneous finger syndactyly	HPO Gene-Disease Associations	1.0	null
SB-674042	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.57
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal vertebrae development	MGI Mouse Phenotype Associations 2023	1.0	null
SUPB15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84247
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10112
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27973
appendix	HPA Tissue Protein Expression Profiles	1.0	0.922682
complete postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
GSN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595337
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25874
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormal presacral vertebrae morphology	MPO Gene-Phenotype Associations	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
CSNK1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487344
Hirschsprung's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Hypoplasia Of Clavicle	DisGeNET Gene-Disease Associations	1.0	null
Perturb_2177_KD_DDX24_SRP339923	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.60877
Catenin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.88852
Perindopril	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
CCL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00946228
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33827
FPGS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0033192
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831808
Van Maldergem syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
C8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540735
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4838
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08228
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857729
Human - Fetal Development - L1 - ENS glia	HuBMAP Azimuth Cell Type Annotations	1.0	null
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2313
Tricuspid valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81511
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03579
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951414
BRD-K86284654_Alfacalcidol_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75136523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91039
Perturb_8470_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91108
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845623
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAKI1	DepMap CRISPR Gene Dependency	1.0	4.59498
SLC9A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00442828
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844696
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96983
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1051
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969277
GSE190555,GSE190557_2_v_3_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04334
Perturb_18495_KO_Ercc2_SRP286486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60917
TEAD2_02_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60039
Perturb_4220_KO_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.89494
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33008
aplasia/hypoplasia involving bones of the upper limbs	HPO Gene-Disease Associations	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3297
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08611
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Recurrent axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.162
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05396879_15-delta prostaglandin J2_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A86748098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19242
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317306
SW579	DepMap CRISPR Gene Dependency	1.0	4.55588
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3466_KO_Chd4_SRP076455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Human - Fetal Development - L2 - Heart-Schwann cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
hsa-miR-1285	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055666
ALDH9A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741913
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
BRD-K26954192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42816
BRD-K54939987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21977
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865298
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Stricture Of Anus	DisGeNET Gene-Phenotype Associations	1.0	null
abnormality of joint mobility	HPO Gene-Disease Associations	1.0	null
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippo signaling	GO Biological Process Annotations 2015	1.0	null
GSTO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494658
TMLHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447007
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207593
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.53908
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1755	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
KMRC2	DepMap CRISPR Gene Dependency	1.0	2.16505
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2835
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.42466
GRIA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00650374
IL3RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668739
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
EFHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693697
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4518	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
morphological abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56376
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64404
abnormal embryonic tissue morphology	MPO Gene-Phenotype Associations	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994363
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32431
BL1681 (BUB1)	NURSA Protein Complexes	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66037
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1052
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.67464
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236476
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.677395
Desipramine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.47
karakoline-3638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
20937356-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Subcortical Band Heterotopia	DisGeNET Gene-Disease Associations	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918246
UMOD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562777
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17332_KD_PUM2_SRP170955	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.1732
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICAM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00904258
KRT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603576
BLUE1	DepMap CRISPR Gene Dependency	1.0	4.3092
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
BRD-K57616143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89216
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841296
BRD-K95264594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48642
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_13915_KD_SLC45A4_SRP173763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30446
BRD-K20285085_R406_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1642
FASTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712061
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10566
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
localized skin lesion	HPO Gene-Disease Associations	1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
Perturb_13099_OE_Dux_SRP220068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.05471
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5823716-onc2017356x6.xlsx-350POS_noreps_txt-Supplementary_Table_4_ESC_SNAI1_FLK1hi_UP_Human_orthologs_of_top_350_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03259
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_384_KO_IKKa_SRP229998	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84069
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8506
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924399
Schwann cell_Skin_Human	CellMarker Gene-Cell Type Associations	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28598
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24071
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13771
BRD-K87909389_alvocidib_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35889
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.857874
LTA4H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565044
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47025
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.15463
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.55453
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866945
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73471
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990907
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79354
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459899
Moderate Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-2110	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
BRD-K91011325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04269
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NT5C3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00903453
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28013
ARL6IP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481893
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26331
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15407
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20352
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67145
HSPA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631096
GJA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515228
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45286
GTEX-OHPL-2526-SM-3MJGT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00603
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.858304
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977089
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0588
Perturb_13491_KD_Ncor1_ERP132013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.20562
Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GRHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818404
Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974705
abnormal digestive system morphology	MPO Gene-Phenotype Associations	1.0	null
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BMP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713659
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45486
SIPA1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645998
BRD-K04147413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22161
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21971
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82764
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40943
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FCGR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517803
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell migration involved in heart development	GO Biological Process Annotations 2025	1.0	null
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
ZNF143	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01391
MYO5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501656
Schwann cell precursor_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09851
RGCC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060508
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal interatrial septum morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal branching involved in ureteric bud morphogenesis	MPO Gene-Phenotype Associations	1.0	null
Perturb_17209_KO_miR92a1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47009
BRD-K23704908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63158
tissue development	GO Biological Process Annotations 2015	1.0	null
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41985
OLIG2	ChEA Transcription Factor Targets	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.765
abnormal sternum ossification	MPO Gene-Phenotype Associations	1.0	null
BRD-K92581247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32105
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96433222_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09895564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55162
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
recessive	GeneRIF Biological Term Annotations	1.0	null
BRD-K50497551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18399
SPTBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672277
ZC3H12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606762
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14257
Perturb_4021_KO_Bcl11b_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51175
Criduchat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39794
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12665_KD_SLNCR_SRP151199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.6866
PANK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00845187
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859218
functional abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
BRD-K59517185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11374
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.116
MYOG	ENCODE Transcription Factor Targets	1.0	null
TRAF3IP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494331
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952206
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL17B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00881898
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
PMC5682285-41467_2017_1744_MOESM10_ESM.xlsx-HIFI_KD-Unnamed_0_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSTA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559149
Perturb_13914_KD_SLC45A4_SRP173763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.47529
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882712
BRD-K97764662_P2499_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572848
GSE201270,GSE201272_0_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40567
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78431006_HY-50878_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.01324
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208023
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.617
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60591
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19439
hsa-miR-4652-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258681
Perturb_16422_KO_Ring1/Rnf2_SRP136552	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.8239
BRD-K52231520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08303
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20208
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	0.922682
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27053
BRD-K12502280_TG101348_A375_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208212
BRD-K77403813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67208
MAX	ENCODE Transcription Factor Targets	1.0	null
C1QBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513238
GBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514063
PADI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608778
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01469
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.35331
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
Collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834209
EPHB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594932
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19967
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32992
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991564
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5738-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30912
BRD-K18787491_U-0126_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42596
abnormal kidney collecting duct morphology	MPO Gene-Phenotype Associations	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.06952
NB1	CCLE Cell Line Gene Expression Profiles	1.0	1.71668
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPATCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586495
EFM19	DepMap CRISPR Gene Dependency	1.0	2.44837
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941401
NCOA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628195
Perturb_1088_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.39682
BRD-K78084463_W-12, Hydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10589
RIOK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508141
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2962
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.945131
RPP40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509185
PMC2882122__F4	PFOCR Pathway Figure Associations 2023	1.0	null
FOXP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441956
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50908
aplasia/hypoplasia of the 4th metacarpal	HPO Gene-Disease Associations	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29241
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.451606
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25292
Fatty Liver	CTD Gene-Disease Associations	1.0	1.4332
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042491
BRD-K28578425_Cilostamide_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48949
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K78126613_MENADIONE_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827442
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17476
Hypospadias	DisGeNET Gene-Disease Associations	1.0	null
NR2F2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_154_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66468
GSE247084,GSE247087_0_v_1_cdyl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8967065__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
Deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.925362
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051429
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31667
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HSD17B3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575312
abnormality of fontanelles	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
FHL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459919
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.81604
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02502
SEMA3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618097
cutaneous syndactyly	HPO Gene-Disease Associations	1.0	null
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XB-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96756
CPNE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00342978
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84187
BRD-K43387144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44922
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clinodactyly	HPO Gene-Disease Associations	1.0	null
KCNU1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534558
PAK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0082349
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.85296
BRD-A45889380_QUINACRINE HYDROCHLORIDE_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_4_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1689
BRD-K97256018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48838
BRD-A60245366_AS-601245_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41091
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24181
abnormal metacarpal morphology	HPO Gene-Disease Associations	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900454
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
SOAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528456
NPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668766
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926062
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
PMC10806738-mmc2.xlsx-Table_S2-Table_S2_Table_of_significantly_adjusted_p-valued_0_05_down-regulated_genes_log2FC_-1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17399
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01218
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33382
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53289
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29419
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37815
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873429
CPED1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561309
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.777737
mitral valve morphogenesis	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19303
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825895
feeding difficulties	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	209.173
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259781
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35071
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
BRD-K79090631_CGP-60474_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE249544,GSE249637_8_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.70796
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
reduced bone mineral density	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Larval brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.251032
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
branching morphogenesis of an epithelial tube	GO Biological Process Annotations 2015	1.0	null
GSE149943_1_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71803
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71048
ALB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0075186
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53538
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16852
abnormal vertebrae morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Coronary Artery Disease	dbGAP Gene-Trait Associations	1.0	0.211564
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52254237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03192
wide sternum	MGI Mouse Phenotype Associations 2023	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.26718
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.234054
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Acne_Sebocyte_GSE10432	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.87038
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2223
Congenital myasthenic syndrome 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909623
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2870_Mut_KEAP1_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.35634
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05721
BRD-K30977850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77372
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30726
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843219
BRD-K96218803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77353
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal size of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
abnormal cochlear hair cell stereociliary bundle morphology	MPO Gene-Phenotype Associations	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36393
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9844011-media-1.pdf-6-ENSG00000118922_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946462
Human - Fetal Development - L2 - Intestine-ENS glia	HuBMAP Azimuth Cell Type Annotations	1.0	null
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95243
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
RIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434513
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76651
NCIH838	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46
PPAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496001
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71622
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22385
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35186
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99470595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37222
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75896
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875774
Peripheral nerve sheath neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
DCHS1-related congenital anomalies of the kidney and urinary tract	ClinVar Gene-Phenotype Associations 2025	1.0	null
IL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639143
Perturb_4073_KO_Bcl11b_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.52522
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50605
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87185
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0203
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.275
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.29576
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.7159
ITPKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540641
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4171
SW48	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22016
biological_process	GO Biological Process Annotations 2015	1.0	null
Schwann cell_Pancreas_Human	CellMarker Gene-Cell Type Associations	1.0	null
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23399
CHI3L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697536
abnormality of bone mineral density	HPO Gene-Disease Associations	1.0	null
dextromethorphan-2636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244017
NDUFA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512559
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55824
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
DMB	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
MDAMB415	DepMap CRISPR Gene Dependency	1.0	2.49386
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NLRP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0104553
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-WFG8-1126-SM-4LVN1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853908
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.43841
specific developmental disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K06332513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0425
BRD-K74148702_curcumin_VCAP_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17471573-Table2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K42855618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73922
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	179.523
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14839
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.82672
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	Achilles Cell Line Gene Essentiality Profiles	1.0	1.08093
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66686
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25874
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79439
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89026
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27174
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7462863-41467_2020_18186_MOESM13_ESM.xlsx-Suppl_Data_11-Supplementary_Data_11_Driver_genes_NOT_found_in_the_Mongolian_cohort_compared_with_previous_HCC_studies_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73032
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
WEE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052444
GALC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049554
BRD-K36027285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00651
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58196
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567863
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45082
BRD-A38030642_cyclosporin A_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14310_KD_CD83_SRP178846	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limbs/digits/tail phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-205	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843012
SNU308	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62035
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9416
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09476
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatitis C infection_Hepatocyte_GSE2067	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.01869
GM133	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41311
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	2.61846
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.922682
PLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530202
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	223.306
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
BRD-K94493764_NP-009169_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92991072_PAC 1_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561657
BRD-K54141134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1464
abnormal thoracic vertebrae morphology	MPO Gene-Phenotype Associations	1.0	null
Double outlet right ventricle	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.894623
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38747
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28242
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.49408
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975626
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.433
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60454848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45381
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03832
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514329
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49087
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863263
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.804267
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Dysgenesis Of Corpus Callosum	DisGeNET Gene-Disease Associations	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22233
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17385
BRD-K96449536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15471
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.31
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35632
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44328
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18219
GRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604693
GET3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0067944
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14732209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85343
PMC10281040-mmc1.pdf-6-ENSG00000118922_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32425
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876955
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909285
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
Perturb_14505_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.3303
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381779
LN443	Achilles Cell Line Gene Essentiality Profiles	1.0	1.26279
BRD-K87537204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05906
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56751
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40003
GSE242290_3_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42103
TOLLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654332
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40560569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51154
SIRT6	ENCODE Transcription Factor Targets	1.0	null
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08638
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554564
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329182
Perturb_1075_KO_Il17a_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.10244
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.546
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.814
hypertelorism	HPO Gene-Disease Associations	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02106
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16687
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38218737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43672
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53947
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
CYTH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509136
PMC5819186-13040_2018_163_MOESM3_ESM.xlsx-Lung-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69914820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73946
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31147
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464049
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.279044
branching involved in ureteric bud morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
short sternum	MPO Gene-Phenotype Associations	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665051
ARIH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00784291
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKNBE2	CCLE Cell Line Gene Expression Profiles	1.0	2.00183
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02567
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436438
SP110	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0075863
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31427
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.55042
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14297
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15233
Perturb_16864_KO_Hdac2_SRP255943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.17291
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953123
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54276
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_12_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222461
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0731
TPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492375
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07761
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93669
GPR61	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569914
BRD-K85456600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44132
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
cdkn1b_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl6246_gse27672	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.01794
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5374
BRD-K80690345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56978
PMC5682285-41467_2017_1744_MOESM10_ESM.xlsx-H1_KD-Unnamed_0_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2157
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18319
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2936
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_123_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.84388
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.684849
Orbital Separation Excessive	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2023	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AADAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620151
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01447
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912258
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25322
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
H2722	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22677
SEMA4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00955591
Microvillar actin bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF1A_01_02	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.8033
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06241
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61687
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31126
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57758
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IC-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69708
SLC25A10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571022
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
Small intestine neuroendocrine neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883617
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
aplasia/hypoplasia of the maxilla	HPO Gene-Disease Associations	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aplasia/hypoplasia involving bones of the feet	HPO Gene-Disease Associations	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4124
interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
C4II	DepMap CRISPR Gene Dependency	1.0	3.53948
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00349
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45876
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3496
BRD-K18307373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05856
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926914
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067097
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.847733
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01163
Cell body fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961932
BRD-K95860374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81173
CL-40	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K21547369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34179
abnormal skeleton development	MPO Gene-Phenotype Associations	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21326
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998454
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
MNDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532892
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04997
Neuroblast_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HD-MY-Z	COSMIC Cell Line Gene Mutation Profiles	1.0	null
small lung	MGI Mouse Phenotype Associations 2023	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
PXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714886
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7544
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97412
CANX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066081
GSE239747_1_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Joubert syndrome with orofaciodigital defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954593
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25146
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-1266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal cochlea morphology	MPO Gene-Phenotype Associations	1.0	null
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16939
abnormality of the metacarpal bones	HPO Gene-Disease Associations	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FTSJ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460849
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214017
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	1.3676
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14816
Perturb_1300_KO_Foxp1_SRP158103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.63757
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OELE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.59838
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23888
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79589
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88190816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30923
16144934-Table3	GeneSigDB Published Gene Signatures	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20875
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7356
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
STL304557	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14249
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27545
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	191.464
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963213
PSG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00925722
seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07265
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.3138
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4623
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
LMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645566
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	1.0	2.26672
Congenital Camptodactyly	DisGeNET Gene-Disease Associations	1.0	null
BRD-K75360899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82298
cell part	GO Cellular Component Annotations 2015	1.0	null
ERBB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACACB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565617
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223039
abnormal mitral valve cusp morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059274
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	362.252
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD48	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716272
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47672
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K42575648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78692
GYPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00376367
syndactyly	HPO Gene-Disease Associations	1.0	null
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26602
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Self-Injurious Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	2.70481
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61942
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.42769
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
Van Maldergem syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.071
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24628
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9225
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
PMC12741043-ACEL-25-e70304-s001.pdf-337-ZNF549_ZNF549	Rummagene Transcription Factor Associations 2026	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.53071
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60797
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06253
BRD-K57044355_NCGC00181061-03_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Posterior spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129321
BRD-K51320582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07326
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the 4th metacarpal	HPO Gene-Disease Associations	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FSHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00765739
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.38426
Downturned Corners Of Mouth	DisGeNET Gene-Phenotype Associations	1.0	null
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8749
BRD-K25138450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62114
BRD-K29542628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33762
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitral valve prolapse	ClinVar Gene-Phenotype Associations 2025	1.0	null
DHRS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616207
IGF2R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00373971
IL36G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465828
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07581
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
atresia of the external auditory canal	HPO Gene-Disease Associations	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ANPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533457
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FZD10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525145
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84608
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
SMOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00844614
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4817
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60336
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
heterotopia	GeneRIF Biological Term Annotations	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10873
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
GADL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055215
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80115
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.72399
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28475
Van Maldergem Wetzburger Verloes syndrome	ClinVar Gene-Phenotype Associations	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4016
Perturb_8029_KO_VPS35_SRP241666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K13566078_BMS-345541_MDAMB231_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SELP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00925841
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.94385
GTEX-TMMY-2226-SM-4DXTN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3891
apical part of cell	GO Cellular Component Annotations 2015	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H226	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49945
IGSF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706765
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
AOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00425255
Perturb_10606_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.01529
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15762
interleukin-5 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1526-SM-3NMCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896916
Perturb_6957_KO_Ift88_SRP179473	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99928
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447879
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3232
CYP2C8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516055
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A45498368_WYE-125132_HS578T_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40947
skeletal dysplasia	HPO Gene-Disease Associations	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88311
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3932
SEPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679063
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39102
Perturb_11495_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.30869
Perturb_16916_KD_Maf1_SRP375944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NEK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00821089
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00112
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04526
TRAF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566357
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843488
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.34741
SIGIRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00415118
PMC8967653__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-A11087911_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04464
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34968
BRD-K90382497_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the fontanelles or cranial sutures	HPO Gene-Disease Associations	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32009
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_14371_KD_IGF2BP2_SRP131243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.79656
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCGF2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00833239
Perturb_3002_KO_Lrp5/Lrp6_SRP116923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.51716
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2143
SKP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588815
ELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490949
Neuroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29936
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647316
NID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562812
BRD-K19672435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30677
GRM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826315
SF126	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03232
ANXA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00346785
DOCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709661
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10278
hsa-miR-933	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70595
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPFIA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627628
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the curvature of the vertebral column	HPO Gene-Disease Associations	1.0	null
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4253
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67273
IFT172	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606042
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51608872_N,N-dimethyl-6-({[1-(1-naphthyl)-1H-tetrazol-5-yl]thio}methyl)-1,3,5-triazine-2,4-diamine_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DICER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812134
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GPR171	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549799
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
LRRC25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00807986
cadherin	GeneRIF Biological Term Annotations	1.0	null
RUNX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566189
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88527
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23319
GTEX-XPT6-0326-SM-4B66V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05662
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917705
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48241
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
dilated renal tubules	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1915	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43283
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175683_3_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neural tube development	GO Biological Process Annotations 2015	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38556
HUG1N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2885
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16623
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70845
Perturb_18143_KO_Nampt_SRP245819	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.37858
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
Human - Heart - L1 - Neuronal	HuBMAP Azimuth Cell Type Annotations	1.0	null
GLUD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763669
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09568
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58845
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532658
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12627
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81472
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VSTM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780866
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835647
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nerve plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20515
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36362
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878717
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26018
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11697
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.8154
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44839
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80348
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828403
PMC5682285-41467_2017_1744_MOESM10_ESM.xlsx-H9_KD-Supplementary_Data_7_qPCR_analysis_in_independent_hESC_lines_and_iPSCs_of_potential_CSDE1-regulated_transcripts_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38075
all	GWASdb SNP-Phenotype Associations	1.0	0.050256
BRD-K02822062_CT-200783_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_1191_OE_CDYL_SRP335863	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K87947369_VX-680_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BCL2L14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529285
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.232
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
Perturb_4967_KD_LHX2_SRP324013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.32009
SGPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579173
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.1609
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
CRCGN015_MCF10A_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01076
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889876
OR2L13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710007
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00936
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.922682
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23783
Perturb_5021_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.79539
BRD-K03176945_7910663_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KIS	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84316
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22568
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855744
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
OIP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553572
PTPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481357
Perturb_17648_KO_CEP83_SRP379856	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.54023
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.508972
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A73909368_DACTINOMYCIN_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12098
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58221
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26074
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41353
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954172
ZR751	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74651
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52914
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61202
abnormality of the sacrum	HPO Gene-Disease Associations	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.042
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35515
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852414
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00113
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46645
SHROOM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00850545
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06746
Perturb_17785_KO_Dnmt3a_SRP188207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4677515__F1	PFOCR Pathway Figure Associations 2023	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16249
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.39314
Anus, Imperforate	DisGeNET Gene-Disease Associations	1.0	null
GSE242290_1_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44198
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.13575
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06862
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38899
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834785
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30625
TBX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00759755
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GUSB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614149
ATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537634
BRD-K82754613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8279
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15462
abnormality of mouth shape	HPO Gene-Disease Associations	1.0	null
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
cell-cell junction assembly	GO Biological Process Annotations 2023	1.0	null
MGRN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586811
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710156
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24066
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02352
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IRF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051951
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
RRM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00766907
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
SIN3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00798891
Scp cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
ACAD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724783
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481396
GPX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523936
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89563
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056176
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60409
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22233
PMC3748736__F1	PFOCR Pathway Figure Associations 2023	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829043
GTEX-S4P3-0726-SM-4AD57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44558
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974194
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A38793261_NCGC00238427-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
lomefloxacin-3723	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02822062_CT-200783_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97377031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00316
abnormal vertebrae development	MPO Gene-Phenotype Associations	1.0	null
Perturb_14664_KD_SMNDC1_SRP337258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49252
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.02283
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsynaptic endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47806
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04952
CAL29	DepMap CRISPR Gene Dependency	1.0	3.98155
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06982
BRD-K05977380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27684
GTEX-S341-1126-SM-4AD6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54959
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10974
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08882
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4354
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4738
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCNN1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00961528
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41317
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.68
KCNK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439672
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833747
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60294
BRD-K28687144_Fosfosal_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57575504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59944
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31041
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49313
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.297
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2042
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.93356
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8X3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85651
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487106
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18947
BRD-K93788137_PF-431396_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
MAZ	ENCODE Transcription Factor Targets	1.0	null
FOXA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059808
BRD-K36848506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19848
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248427
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865402
NDC80	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667167
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23942
BRD-K53414658_-666_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584149
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51258
BRD-K95941120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0799
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586267
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5455
FOSL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566112
RASopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Octreotide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of long bone morphology	HPO Gene-Disease Associations	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46107
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63571
Lateral cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K43479153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.269
Peg and socket contact	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
PPP4R3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721612
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.189539
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951159
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28302
BRD-A63346720_Rimcazole dihydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LPCAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059937
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12619
fat4	GeneRIF Biological Term Annotations	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06325
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22233
cell migration involved in heart development	GO Biological Process Annotations 2023	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20938
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GAST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591959
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35201
HS294T	DepMap CRISPR Gene Dependency	1.0	3.98693
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pupal wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50613
intellectual disability	HPO Gene-Disease Associations	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1648
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09263
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.7257
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8789288-elife-73137-supp3.xlsx-Gene_List_Comparisons-Supplementary_file_3_Comparison_of_genes_induced_by_IRF1_or_IFNg_with_genes_in_the_type_II_ISG_screen_library_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84104
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular	GeneRIF Biological Term Annotations	1.0	null
Neuronal Heterotopia	DisGeNET Gene-Disease Associations	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23404
HTR2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00761902
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26558
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.16
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44124
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.14104
MG-63	GDSC Cell Line Gene Expression Profiles	1.0	1.57389
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978295
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04242
Perturb_5022_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653127
Cadherin signaling pathway	PANTHER Pathways	1.0	null
LCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619469
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22118
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880972
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1071
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15013_KO_Stra8_SRP150721	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43816
Perturb_17689_OE_METTL14_SRP401650	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.8697
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954626
OV-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7085
HLA-DQA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616493
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.495197
PCCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484639
FDFT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00320907
PMC10290283-biol-2022-0622-sm3.pdf-219-ZNF394_ZNF394	Rummagene Transcription Factor Associations 2026	1.0	null
Primary autosomal recessive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
BRD-K70154746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18291
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27245
ILK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049828
BRD-K54839019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66939
STAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583619
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HVCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502851
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELSR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476986
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838583
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40964
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.467
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0103395
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37694030_DOXEPIN HYDROCHLORIDE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CATSPER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00656795
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51272331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37578
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26184
BRD-A25687296_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MIA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587367
GTEX-S32W-1526-SM-4AD6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72628
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27787
WIPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00756139
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40341
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78256
Neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
vascular disease	GWASdb SNP-Disease Associations	1.0	0.089089
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95243
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29543
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318438
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6299
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00419094
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
18689800-TableS7	GeneSigDB Published Gene Signatures	1.0	null
KDM5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00387119
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4141
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85391
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3187-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05676
GTEX-S7SF-1026-SM-4AD4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994129
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2850_Mut_NRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268956
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48016
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40447
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918898
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
abnormality of the calvaria	HPO Gene-Disease Associations	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918637
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43449
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07325606_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83791
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995929
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01231
FDCSP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052908
NTRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004999
GPAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537089
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kenyon cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.992
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93324
STS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427035
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894122
BRD-K74148702_curcumin_HT29_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78782
17975224-TableS6	GeneSigDB Published Gene Signatures	1.0	null
Narrow Forehead	DisGeNET Gene-Phenotype Associations	1.0	null
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16607
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17281
Thiothixene	DeepCoverMOA Drug Mechanisms of Action	1.0	0.78
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
Short Clavicle	DisGeNET Gene-Phenotype Associations	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.188
hippo signaling	GO Biological Process Annotations 2025	1.0	null
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03953
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868535
BRD-K68336408_Tyrphostin AG 1478_RMGI_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHP-134	GDSC Cell Line Gene Expression Profiles	1.0	2.37061
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00832
GTEX-SUCS-1126-SM-4DM61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17299
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCHEMBL5061501	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
small lung	MPO Gene-Phenotype Associations	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845678
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38342
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.062471
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50236
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953108
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3798
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal organ of corti morphology	MPO Gene-Phenotype Associations	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33525
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
Melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Subesophageal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
abnormal lumbar vertebrae morphology	MPO Gene-Phenotype Associations	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5694
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
NELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609838
MO-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581218
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40456
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318912
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76489
BRD-K88421348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07104
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Aortic valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-K04548931_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.30601
H3K27me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.649992
BRD-K20199304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0541
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
KCNJ5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808801
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03747
TFDP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694254
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	182.806
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-138	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0759
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56531121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49027
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4907-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.06381
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830303
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.95015
Thiamet G	DeepCoverMOA Drug Mechanisms of Action	1.0	1.0
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897573
BRD-K50942788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36916
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99439
dopamine-491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF280B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660354
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16344
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
Neurofibroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
CD300C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691431
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catenin complex	GO Cellular Component Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02502
GBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00831292
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65253
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37367
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28407
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2623
Sternal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427338
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58824
abnormality of the corpus callosum	HPO Gene-Disease Associations	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03664
PMC3748736__F1	PFOCR Pathway Figure Associations 2024	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28129
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09828
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062185
nervous system development	GO Biological Process Annotations 2023	1.0	null
ROBO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546122
Achilles bursitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
SMKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689342
Perturb_12850_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.43509
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38171
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13839_OE_Mir200_SRP124784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.7305
Ceritinib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.23
PDE7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642609
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29678
Perturb_11763_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76318
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00898
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58557
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87953
abnormal appendicular skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.351794
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMX1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600292
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K60895802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08342
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24172
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248097
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10746
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11231
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9863
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45969
sleep disturbance	GWASdb SNP-Phenotype Associations	1.0	0.974784
curly tail	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K80575072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41407
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69042
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478202
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58270905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06028
Perturb_6968_KD_Dnmt3a_SRP075146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3742
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney cyst	MGI Mouse Phenotype Associations 2023	1.0	null
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20441
cell-cell junction organization	GO Biological Process Annotations 2023	1.0	null
18277965-Table4b	GeneSigDB Published Gene Signatures	1.0	null
cell-cell adhesion mediated by cadherin	GO Biological Process Annotations 2023	1.0	null
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96443
abnormal intestine morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923311
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Juvenile absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.527
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
IL12RB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632939
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	476.293
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.20088
dchs1	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16866_Mut|KO_Htt_SRP255943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.88063
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
NDUFS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554847
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
20436685-ST4-2	GeneSigDB Published Gene Signatures	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.47555
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
Huntington's Disease_Blood_GSE1751	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54465
Perturb_699_KO_INTS6_SRP299234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6411
YY1	ENCODE Transcription Factor Targets	1.0	null
CDK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739223
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
DJM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18144
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895235
ATXN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583625
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964934
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A23770159_Rapamycin_SW948_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKBIE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710276
abnormality of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.889796
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K18629365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00065
BRD-K79090631_CGP-60474_MDAMB231_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
12941840-Table1	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hexestrol-5776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12067
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21616
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873884
BRD-K30488928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60607
Neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35972
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06927
IDH3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00745601
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46238
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94084
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital heart disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06535
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979796
decreased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REG1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564794
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956575
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20234
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22233
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7599
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80744
TREML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532455
GR-ST	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79608
GRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685637
BL5475 (BRD1)	NURSA Protein Complexes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02706
BRD-A09164687_1495-0136_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
morphogenesis of an epithelium	GO Biological Process Annotations 2015	1.0	null
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1734
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71547
Twig	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91698
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45423
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27305
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07995125_KUC104487 KUC104487N_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
BRD-K69932463_AZD-8055_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TUBB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508849
FGFR1HighNME5- epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K01417352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72531
Proteinuria	CTD Gene-Disease Associations	1.0	1.09576
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1595
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955151
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.40597
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90534
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4734
hsa-miR-589	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8312441__F7	PFOCR Pathway Figure Associations 2024	1.0	null
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77581
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2023	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22897
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53143
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904927
UGT1A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529706
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972736
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05636
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21348
AMZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00760517
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1724
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883907
PDGFRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00778559
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924399
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60628
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28514
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975166
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42062
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the urethra	HPO Gene-Disease Associations	1.0	null
PMC5575985-mp2016192x3.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC50A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00974602
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01151
GPR17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568244
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE224311_3_v_0_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88988134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03242
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5899
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34122
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
VPS18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593238
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30539
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TESK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520821
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18715
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20961
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963951
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.049475
GPR87	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537412
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.4378
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
U251	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.824314
intellectual disability	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
SDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043796
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1168
GM2313	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
abnormal neural tube morphology/development	MPO Gene-Phenotype Associations	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441197
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	1.0	1.60865
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29955
Ehlers-Danlos syndrome musculocontractural type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23573
BRD-K58977196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17751
Perturb_6720_KO_KDM3A_SRP128505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3028
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71021
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45479396_BP 554 maleate_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALDH1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00360914
Perturb_698_KD_CEBPA_SRP159689	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76421
SAMD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544619
aplasia/hypoplasia of the external ear	HPO Gene-Disease Associations	1.0	null
abnormal vertebral column morphology	MPO Gene-Phenotype Associations	1.0	null
CSNK1G1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704021
short metatarsal	HPO Gene-Disease Associations	1.0	null
BRD-K37865504_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LDHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424975
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.54767
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02502
Lung squamous cell carcinoma_LUSC_TCGA-63-7022-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983392
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833496
SLC19A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0086347
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
BRD-K57687960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21023
Pachygyria	DisGeNET Gene-Disease Associations	1.0	null
RNASEH2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574093
uterus	GTEx Tissue Gene Expression Profiles	1.0	1.40005
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16016
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934015
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24865
CASP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530904
abnormality of the anus	HPO Gene-Disease Associations	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304919
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02646
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5817
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7776
BB-93-VT73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201285
BRD-K90127029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26983
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13945
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11742
BRD-K94176593_TWS-119_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.659979
BRD-K03829970_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67566344_KU-0063794_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16446
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1257
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.2716
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5849
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4197
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10997
BRD-K51643438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40946
felodipine-337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923094
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53366
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.777
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.37813
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LCP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481402
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.85547
BRD-K53026281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.106
BRD-K08417745_SID 26681509_NCIH1836_6.0_h_88.8_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.763
hsa-miR-324-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2023	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K98505253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15057
Hypertrophy	CTD Gene-Disease Associations	1.0	1.32518
AIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575997
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Papaverine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.25
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.05778
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18619
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902719
SFTPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063309
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371316
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853037
ACSM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636156
PRSS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687201
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66175
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.764079
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.82147
CBX2	ENCODE Transcription Factor Targets	1.0	null
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2241
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
PMC6295312__F1	PFOCR Pathway Figure Associations 2024	1.0	null
lead	GeneRIF Biological Term Annotations	1.0	null
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98757606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26925
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36091
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7367-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49195
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827754
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75206
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34279
morphogenesis of a branching structure	GO Biological Process Annotations 2015	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19499
CROT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574102
abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228062
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04392
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847914
hsa-miR-3155	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946266
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52054012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07802
Perturb_4290_KO_Clybl_SRP374413	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.88672
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.922682
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5582996__F1	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46581
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883565
BCAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554897
dental malocclusion	HPO Gene-Disease Associations	1.0	null
Calcium	HMDB Metabolites of Enzymes	1.0	null
PGA1	DepMap CRISPR Gene Dependency	1.0	4.13036
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27132
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
PDE11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00785512
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00395493
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4876
SH2D1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682771
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
high palate	HPO Gene-Disease Associations	1.0	null
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064881
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31143
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	209.256
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13985
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05567
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24684
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23425
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970603
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60797
BRD-K52339692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03339
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877047
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19814
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K19534880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38084
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1938
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13212
DTHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465692
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252843
BRD-K50836978_Purvalanol A_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
talampicillin-7014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3374
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51063
hsa-miR-485-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
DU145	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.977586
BRD-K79090631_CGP-60474_MDAMB231_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.6433
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12862
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22195
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957863
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94816
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02844
BRD-A13122391_16-HYDROXYTRIPTOLIDE_A375_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
CTHRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642797
GCIY	DepMap CRISPR Gene Dependency	1.0	4.00317
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21107
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14696
BRD-K36638198_FELAMIDIN_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOMER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436368
KEL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738099
KMRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82834
PRKG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640125
Perturb_13875_KO_LIN28B_SRP335506	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.1611
Cul4A-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.47
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220562
ectopic anus	HPO Gene-Disease Associations	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.586
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VWA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049641
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02347
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878905
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21311
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392775
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960164
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2051
GRIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506883
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496849
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12389
Perturb_9488_KD_Appbp2_SRP359770	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.53453
BRD-K86232678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19734
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
Heterotopia, Periventricular, Autosomal Recessive	CTD Gene-Disease Associations	1.0	2.88009
LUDLU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54631
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833585
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43398
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TMIGD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587896
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K11414036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03369
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
talipes equinovarus	HPO Gene-Disease Associations	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2761
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887167
YES1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529922
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57027
RNF43	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652214
Lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
BRD-K42191735_buparlisib_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sacrococcygeal pilonidal abnormality	HPO Gene-Disease Associations	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848956
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.465
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.147
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62797
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
abnormal joint morphology	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia of metatarsal bones	HPO Gene-Disease Associations	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941116
abnormal nervous system development	MPO Gene-Phenotype Associations	1.0	null
SK-N-DZ	GDSC Cell Line Gene Expression Profiles	1.0	1.75823
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	2.11906
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63288
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16899
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53414658_-666_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07941
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03277
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874707
NFIC	ENCODE Transcription Factor Targets	1.0	null
Seckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2794
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850927
CXCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049999
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22403
BRD-A41916216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07262
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25526
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3197637-pone.0026348.s009.xls-TableS5_KD_ROSS2_sigTab_telamlK-Gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.84877
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47197953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68571
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18689
GABRA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487937
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2015	1.0	null
nitrendipine-336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pair	GeneRIF Biological Term Annotations	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH520	DepMap CRISPR Gene Dependency	1.0	3.11373
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.29453
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71824
CLCN7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558118
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17706
BRD-K30867024_SB 216641 hydrochloride_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694337
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04015
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44293
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78343
GRIK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611038
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.5437
BTLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639568
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487189
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
CRHR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692702
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873462
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12858_KO_Ift88_SRP125630	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99928
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.56646
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68095
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.799
DXO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00945952
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47255
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592531
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71460915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63201
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24641
ST8SIA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531254
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
Perturb_4124_KO_Dnmt3a_SRP172565	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.45877
Nateglinide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
BRD-A19037878_trichostatin A_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05607
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211796
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15819
AAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490224
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70649
BRD-K18783332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38058
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K48835953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18612
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.312936
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29651
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32189
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937996
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87668
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78078
abnormality of the metatarsal bones	HPO Gene-Disease Associations	1.0	null
XBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480421
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.908553
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077714
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99156
TOP1MT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536699
SLC4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549237
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852278
MFE-280	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blepharophimosis	HPO Gene-Disease Associations	1.0	null
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33387
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.41501
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01798
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846312
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abdominal symptom	HPO Gene-Disease Associations	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cinchonine-2133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29696
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68285
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6872
endometrium	HPA Tissue Gene Expression Profiles	1.0	1.14673
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.93562
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874951
BRD-K02113016_olaparib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72095
Loeys-Dietz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19519
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874707
BPH1	DepMap CRISPR Gene Dependency	1.0	2.19934
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
BRD-K64800655_HY-11001_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.276
abnormal postnatal growth	MPO Gene-Phenotype Associations	1.0	null
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850315
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89573
disease of mental health	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K43926323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80968
AHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610304
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93488589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11073
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880794
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NQO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494447
NADSYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450031
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85202
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37175
BRD-K70549064_EI-156_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07063
PDGFRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00823516
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7734-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	3.12618
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
paclitaxel_homo sapiens_gpl570_gse19136	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EDN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525218
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03734
TLR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517208
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938008
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
Bilateral Choanal Atresia/Stenosis	DisGeNET Gene-Disease Associations	1.0	null
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520549
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924221
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
BRD-K45964657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07076
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00646
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159074
Fetal Death	CTD Gene-Disease Associations	1.0	1.0608