association	dataset	threshold value	standardized value
BRD-K31554491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74218
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K26431593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1832
PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31133
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165567
disease	GWASdb SNP-Disease Associations	1.0	0.095542
K562_Raltitrexed_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016082
Fibrinogen Assay	DisGeNET Gene-Phenotype Associations	1.0	null
NR3C1	ChEA Transcription Factor Targets	1.0	null
BRD-K03608799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09952
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859702
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15474
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.86113
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211332
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160449
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.00514
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11611
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34985
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23676
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61697
BRD-K23860926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03011
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0896
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06782
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6006
MEL-JUSO	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81759
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50006
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14802
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0401842
ion binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16108
BRD-K96438475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34721
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191110_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40301
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0428618
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.069076
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.74222
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	2.13251
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844448
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938212
Simian Acquired Immune Deficiency Syndrome_T lymphocyte_GSE4785	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.14749
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402062
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49649
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912761
C3A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93129
K562_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188121
3-hydroxy-DL-kynurenine-5641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8805_KD_PTB_SRP069229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36308
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0289673
Mouse - Motor Cortex - Cross-Species Cluster - Lamp5+ GABAergic neuron_3	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221386_2_v_0_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63476
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22663
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.39177
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017949
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.00848
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968809
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.105297
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16307
PMC6070353__F2	PFOCR Pathway Figure Associations 2024	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040285
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05032
BRD-K92191804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44295
Kibra-Ex-Mer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
Invasive lobular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045614
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0987
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25694
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05275
hsa-miR-4796-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230238
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239764
BRD-K00083518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28954
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871568
TE15	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13101
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10671
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93675803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38786
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.693418
K562_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141292
k562	HPA Cell Line Gene Expression Profiles	1.0	1.22379
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86497
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0451
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00988
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT20	CCLE Cell Line Gene CNV Profiles	1.0	3.26932
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93095
T173	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24865
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58544
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82873
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0451
Pineal parenchymal tumor of intermediate differentiation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932848
SNU626	CCLE Cell Line Gene Expression Profiles	1.0	1.72756
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.089641
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52106
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38163
K562_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196167
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25303
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0253888
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.933984
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	1.56355
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15927
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313666
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB468_BREAST	CCLE Cell Line Proteomics	1.0	2.16262
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349553
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11625982-AJH-100-10-s001.pdf-86-ZBED1_ZBED1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Rucaparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149386
K562_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223359
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892806
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876496
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K48922193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66631
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50342
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12799
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.889566
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50127933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36696
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1186
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36209
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221789
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.04906
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27646
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC7738566__F3	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33386
BRD-K67632894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13568
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06079
BRD-K61316494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39179
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32686
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827226
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.198058
K562_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.036379
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HDAC2	ENCODE Transcription Factor Targets	1.0	null
K562_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153789
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5989
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_2390_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hexestrol-2515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8509
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.44672
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24538
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0702
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.811702
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884453
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01435
BRD-K55402144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39906
K562_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0252701
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bilirubin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910593
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.075225
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244783
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25375
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871128
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213676
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00518
oxaprozin-4352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
cell adhesion	GO Biological Process Annotations 2015	1.0	null
BRD-K41878930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22769
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5116-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0351365
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914053
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96175
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076483
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97042
SAFB2_02_150	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61963
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
BRD-K10404799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45832
hsa-miR-1246	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_15142_KD_LINC00473_SRP257261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66024
BRD-K78995236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42293
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_3241_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.94523
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34896
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473343
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11469
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.120006
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12725
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HSD17B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63299
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07416
MITF	ChEA Transcription Factor Targets	1.0	null
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11181
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210408
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7738566__F3	PFOCR Pathway Figure Associations 2024	1.0	null
K562_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225647
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850914
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.99825
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Frontonasal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
sperm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.102208
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21289
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5204
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52365
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96201
BRD-K91043938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15593
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40726
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.19001
CRCGN008_HEPG2_24H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3254
BRD-K29441085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60061
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0409284
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11557
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857511
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0327
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4407
Perturb_13886_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.397
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362261
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoblastic leukemia	GWASdb SNP-Disease Associations	1.0	0.416338
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03967
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229111
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3429
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K57251296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36089
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
fludrocortisone-3785	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50445
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11987248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80423
PMC11116544-41698_2024_606_MOESM2_ESM.pdf-0-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07276022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03002
ZNF829	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00481
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65354
BRD-K70844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06299
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49678
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34441
etofenamate-3989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17451
CRCGN009_HEPG2_24H:F18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22967
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36849
Alzheimer's disease (age of onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50837
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.14386
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
affecting	GeneRIF Biological Term Annotations	1.0	null
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39747
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832835
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84532
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Human - Motor Cortex - Cluster - THEMIS+ SNTG2+ Layer 6 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
RB-80-II48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302127
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hip Fractures	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
Adult pineoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0382
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28031
K562_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197532
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cleidocranial dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241763
NCIH660	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04599
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.811702
K562_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0372785
arteriosclerotic cardiovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099363
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	1.68078
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
GTEX-S32W-1126-SM-4AD5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06232
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.150161
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BD-69-XG81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289436
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.584
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
EW-3	GDSC Cell Line Gene Expression Profiles	1.0	2.18383
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888956
BRD-K51411441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7366
PMC12486367-Supplementary_Data2.pdf-327-ZNF263_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4107
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9105
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Blood Coagulation Factors	dbGAP Gene-Trait Associations	1.0	1.75064
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0443
POLR2A	ENCODE Transcription Factor Targets	1.0	null
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161097
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11818
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3068
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39687
UDSCC2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipid metabolism disorder	GWASdb SNP-Disease Associations	1.0	0.838567
BRD-K48611791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32145
Melanotroph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26341
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.284931
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206128
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99482
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K88485670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28325
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023906
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14856
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24097
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE134896_0_v_7_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11678
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06893
Thyrotoxic hypokalemic periodic paralysis and Graves disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11871
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67999
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EB-33-ZP53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264023
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128757
CL11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58147
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1725
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00191
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913466
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4117
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03231
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8877
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38835
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25004
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3299
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52014
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EKVX	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44315
chr4_154005088_T_A_b38	GTEx eQTL 2025	1.0	1.59217
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873973
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10087
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89342
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8676
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0646
BL-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27305
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85122
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59551
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285999
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.158
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836026
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36461
Prestwick-675-2187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
influencing	GeneRIF Biological Term Annotations	1.0	null
Sitagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	2.48
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55248
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18908
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831195
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19246
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08359
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039251
Small_Intestine-duodenum glandular cell	Tabula Sapiens Gene-Cell Associations	1.0	2.02293
Lung adenoid cystic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Perturb_2125_KO_AMBRA1_SRP288295	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.34799
SKES1	CCLE Cell Line Gene Expression Profiles	1.0	2.59261
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76334
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19567
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15507
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14536_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.54632
LU65_LUNG	CCLE Cell Line Proteomics	1.0	9.18855
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021724
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50397
Perturb_16106_KO_Bap1_SRP360900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29079
BRD-K09261031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30773
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380395
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877626
Lipoproteins	dbGAP Gene-Trait Associations	1.0	0.195521
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70708
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RT112	Achilles Cell Line Gene Essentiality Profiles	1.0	1.88012
BRD-K19245310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06246
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	3.04627
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400966
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10869
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.811702
chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341126
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062728
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878388
LOXIMVI	GDSC Cell Line Gene Expression Profiles	1.0	1.44772
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907088
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3794
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53685
BRD-K44203030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15049
K562_Busulfan_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148871
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50971
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58604
K562_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248012
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935672
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57829
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2132
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0114
E2F6	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144313
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.3072
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Doramapimod	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.67
Fumagillin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.811702
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Macular thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825759
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-FX-A3RE-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast liposarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69698
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874076
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23665
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392314
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03549232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91569
K562_JNJ-26854165_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0324765
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43213
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949228
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1619
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TC71	CCLE Cell Line Gene Expression Profiles	1.0	2.07334
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25549
fads1	GeneRIF Biological Term Annotations	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
EW-22	GDSC Cell Line Gene Expression Profiles	1.0	2.17861
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05364
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.098076
IKZF1-21737484-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35357
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61735
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
K562_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182623
K562_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163994
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4441
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
KASUMI2	CCLE Cell Line Gene Expression Profiles	1.0	1.80779
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.146106
bilirubin metabolic disorder	GWASdb SNP-Disease Associations	1.0	1.67662
BRD-K75806288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4798
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360129
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086863
K562_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.025238
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04266
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04813
BRD-K35369722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2248
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11033
K562_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165829
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051932
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A64985224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90368
Perturb_14093_KD_HDAC1_SRP199194	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.00854
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15092
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152923
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33845
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10767
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29992178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19745
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412314
K562_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0249725
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50011
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987016
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21745
K562_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.025069
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17186
BRD-K04810287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16847
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10309
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.67617
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03828
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
K562_Maraviroc_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159035
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183706
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942737
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06679
CRCGN014_HEPG2_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01038
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08179
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.633957
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10902
preribosome, small subunit precursor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11437379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03213
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38698
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181504
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CP-690334-01-4558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01757
K562_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154793
K562_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0320274
JUND	ENCODE Transcription Factor Targets	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05785
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828704
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96683
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329438
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dementia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
UM-UC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59919062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40853
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015338
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533823
BRD-K85311003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39071
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caffeic acid-6753	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231829
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Keipert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2258
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41961
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ONDA9	DepMap CRISPR Gene Dependency	1.0	5.59336
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.817403
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.45268
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05215
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30089
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.69327
BRD-K17886576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37435
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14686
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848215
K562_Tacedinaline_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230682
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60005
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869874
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955944
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564788
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20612
BRD-K55895855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75541
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22108
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13004
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96468
GATA1	ChEA Transcription Factor Targets	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30794
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85597
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22818
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92414
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
SK-MG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52703
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	1.90628
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7549
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07713
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0261592
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30365
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
BRD-K78192025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07924
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83386
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27981
Perturb_11770_KO_Stat3_SRP128652	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74895
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542872
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80337
BRD-K73678117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06484
K562_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0398663
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1761
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Basal body patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
BRD-K98890753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00983
SU-DHL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27647
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23877
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Alisertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020183
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17742
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4106
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
MAX	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34645
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.031875
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87839
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03559
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922639
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	2.25943
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74068
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26034
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366541
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	2.10454
multiple sclerosis	GAD Gene-Disease Associations	1.0	null
A-704 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95575
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873896
Heart endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01703
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04782
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530938
loracarbef-5073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.028409
BRD-K02065805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20148
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23951
BRD-K55972185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7538
Perturb_569_KD_CYGB_ERP113118	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.41886
CL-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K28165749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31538
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.83404
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371163
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32843
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170297
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48304
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295307
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19567079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24229
Tadalafil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Fibrinogen Activity	DisGeNET Gene-Phenotype Associations	1.0	null
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.47039
PD-60-FM93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375058
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877626
H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A08363225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75335
K562_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250384
acute lymphocytic leukemia	GWASdb SNP-Disease Associations	1.0	0.576591
SC-12738 (CSNK2A1)	NURSA Protein Complexes	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36124
BRD-K94058780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2307
K562_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0345622
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40108
hsa-miR-522	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01866
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880879
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28541
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05025
K562_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164682
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
BRD-K37254228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3501
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.643
SC-198 (CCNE1)	NURSA Protein Complexes	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.313
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16812_OE_HNF1A/FOXA3/PROX1_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.46334
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279307
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29774
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05222
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94051
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.01147
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65032
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1656
K562_Pelitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0336309
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86502
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.10889
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
AC-50-FR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265225
K562_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203961
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.996042
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908269
K562_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175076
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08585
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392397
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208875
K562_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0287361
BRD-K11117868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60707
TA-20-FO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308903
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14664
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01954
K562_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014135
CREB1_01_04	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.31064
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06273
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5816
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-3180-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45462
K562_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202112
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25017
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_UNC0631_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137864
K562_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216913
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309395
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930071
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19496
Cnidoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
BRD-K48987279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35913
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16243
CHOP-C/EBP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46913557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09344
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.504
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
BRD-K43543979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32396
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392273
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05012
BRD-K79521948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63572
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	1.08774
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.02815
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.53037
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3316
BRD-K23366960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35035
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6667
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K18984088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6097
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289284
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00673
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75924
BRD-K91980109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15827
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022619
BRD-K29652917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10533
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255243
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088043
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237654
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K27352194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81847
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HEPG2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17213
QC-76-GI57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212264
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824174
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46472
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blood coagulation factors	GAD Gene-Disease Associations	1.0	null
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12332
BRD-K07278815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84647
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.47588
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21998
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
K562_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0298945
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10828
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155006
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4845
BRD-K84988480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2248
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947024
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63184
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08446
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852898
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19167
K562_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159369
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
K562_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016615
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0306614
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043351
K562_AZD1480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180887
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08774
tauopathy	GWASdb SNP-Disease Associations	1.0	1.24194
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045379
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.213
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871938
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98948
BRD-K32472782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44086
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07067
K562_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140615
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050536
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16573
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885962
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202509
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929196
K562_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0275703
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53932
CRCGN015_MCF10A.TP53.M_24H:K15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03375
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20628
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47631
BRD-K80575072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0494
K562_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179656
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.944102
WD-62-UB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215153
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-GSEA_siYAPsiTAZ-SITAZ_UP__MYC_EZH2_H3K27M3BOUND_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6844
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180224
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5464-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	0.838567
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.19684
Congenital mirror movement disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
CREB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K35635390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11545
BRD-K47438870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00965
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94312
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856847
BRD-K23669327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08201
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38361
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80759
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.766991
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967503
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056387
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13398
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23855
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827405
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68003
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K02240568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06185
JHOC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53773
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08035
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.817978
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17653
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37823
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161971
K562_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0342603
K562_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162536
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24396618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33779
chr4_154497547_A_G_b38	GTEx eQTL 2025	1.0	4.44152
fibrinogen	GAD Gene-Disease Associations	1.0	null
K562_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223786
nizatidine-3047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3922
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07156
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33962
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967915
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF295_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.96941
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82072
asiaticoside-3504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_12145_KD_Sp7_SRP272567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Baricitinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.71
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17373
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861595
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	7.08707
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984626
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.793
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.574183
K562_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0314082
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44338
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEPG2_LIVER	CCLE Cell Line Proteomics	1.0	6.23711
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02469
697	CCLE Cell Line Gene Expression Profiles	1.0	1.73917
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00541
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3995
SB-29-ZH97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262496
HGC27	CCLE Cell Line Gene Expression Profiles	1.0	1.34819
Perturb_17545_KD_EFB1_SRP357509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5702
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387087
BRD-K42785890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08605
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936579
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10912
BRD-K12493093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38263
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051732
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10863
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10904
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274394
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1121_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.29172
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26379
D-423MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K35614154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20638
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.469373
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75545
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52848
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11748
K562_Ki8751_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154501
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911007
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.939
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.059278
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26942
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.486861
CRCGN011_HEPG2_24H:E12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0805
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Electrocardiogram morphology (amplitude at temporal datapoints)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K06450191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38027
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18154
Breast lobular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
MN-60	GDSC Cell Line Gene Expression Profiles	1.0	1.5762
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25165
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K37480258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04248
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3465
Balicatib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.87
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0342898
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1096
Perturb_4365_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22532
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01699
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
oxolamine-3006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.15826
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8403340__F3	PFOCR Pathway Figure Associations 2024	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0769
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02257
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152378
K562_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015316
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38357
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.055165
NONO_02_149	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58739
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263992
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3611
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7554
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883368
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.326571
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47465
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7775
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239289
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25598
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11737
Breast neuroendocrine neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
PMC3022822-1471-2164-12-11-S11.XLS-Sheet1-Additional_File_11_SOX2_binding_and_changed_in_gene_expression_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040853
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.444358
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48995
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75884
K562_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01358
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K20030272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28067
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11493601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15157
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43776
SPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12206
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_18494_Mut_Ercc2_SRP286486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.42556
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27079
BRD-K01142063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01211
facial morphology traits (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13406
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157048
alm	GeneRIF Biological Term Annotations	1.0	null
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00842
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33835
BRD-K45665532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70705
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42245
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	1.11203
K562_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191502
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05931
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	0.811702
20203266-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
Human - Motor Cortex - Cluster - FEZF2+ SH2D1B+ Layer 5-6 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247743
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7927
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0774
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70019
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14153
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.77053
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00123
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.268
K562_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019116
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18558
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79863
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69272
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17787
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207832
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
K562_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01996
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04733
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09592
Perturb_15163_KD_PGR_SRP097736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41101
pre-T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828788
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.001
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18291
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06318
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K94647035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11153
K562_Avagacestat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0399807
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.02387
BRD-K82433264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03156
BRD-A97198094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09635
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36031
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330667
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.146596
Nose morphology	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6699
K562_XAV-939_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199556
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13827
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08637
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35681
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34407
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:I23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24876
PMC9706722__F3	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2602
K562_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.025996
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84476
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909814
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23196
BRD-K42757676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09188
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14638
Kidney Chromophobe_KICH_TCGA-KN-8429-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27342
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K54384984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04022
BRD-K58277621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8836
Perturb_14017_KD_PGBD1_SRP398441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.39813
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92543
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_18390_KO_923_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97093
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17893805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04246
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	2.43692
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98827
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.706258
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89298
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.93785
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71391
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7622
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0333229
K562_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0290204
K562_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193705
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07451
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cortex	GeneRIF Biological Term Annotations	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00893
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
pipemidic acid-6752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972891
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87580376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70639
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1694	DepMap CRISPR Gene Dependency	1.0	3.20305
NCI-H82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1906
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841286
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06637
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6152
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92445
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05136
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Celecoxib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151563
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03788
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.87332
CTBP2	ENCODE Transcription Factor Targets	1.0	null
LS513_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.7699
BRD-K24599650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12425
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398634
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EFE184	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01675
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.68666
TD-09-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223651
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54434
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	2.54682
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-499-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84381
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10199
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01923
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
K562_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0255474
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.3845
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214334
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282845
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3418
KYSE150_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.33678
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051561
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_8798_OE_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.39372
hsa-miR-499a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986491
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
STAT3	ChEA Transcription Factor Targets	1.0	null
Perturb_14908_OE_PLZF_SRP127511	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.33697
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
AZ521	CCLE Cell Line Gene Expression Profiles	1.0	1.60306
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.839664
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22471
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302709
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014189
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.063318
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921874
BRD-K34009761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15997
BRD-K18527484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14734
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blood Pressure	dbGAP Gene-Trait Associations	1.0	0.767089
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218607
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35005
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K67902591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19405
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cyclin K-CDK12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279763
K562_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178471
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bilirubin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
BRD-K75845970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16457
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02801
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14221
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3975
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.613764
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71065
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54179
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11799
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64549
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99478
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04841
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923158
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185254
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09503
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885512
BRD-K49050984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00848
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-01-FB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378227
LU65	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58944
BACH1	ENCODE Transcription Factor Targets	1.0	null
Perturb_1171_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25995
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043042
NCI-H838	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65046
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.971461
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33274
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86887
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75317
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K91397206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80722
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37723
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68717
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20956
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44838
PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_239_KD_CYFIP1_SRP061192	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.50945
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967245
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	239.61
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.6095
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887498
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55986
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32577562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12203
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1713
Paranoid schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15991
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
overnutrition	GWASdb SNP-Disease Associations	1.0	0.775076
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133683_3_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219649
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09942
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.942852
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27607
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33213
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864412
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945018
Alzheimer Disease	dbGAP Gene-Trait Associations	1.0	0.552134
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03537
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SD-208	DeepCoverMOA Drug Mechanisms of Action	1.0	2.13
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07951
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76686
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66336
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95242
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Ivosidenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0237495
BRD-K50941255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01481
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.55944
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
hsa-miR-516a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85067
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833959
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
containing	GeneRIF Biological Term Annotations	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02843
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20545
BRD-K54948591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58028
Human - Motor Cortex - Cross-Species Cluster - Layer 6 glutamatergic neuron, corticothalamic-projecting_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30051
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34141
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40296
K562_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0255863
BRD-K41809257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30675
K562_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0289305
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93335
K562_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211186
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84461
BRD-K24598235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82923
chr4_154479700_T_A_b38	GTEx eQTL 2025	1.0	1.36744
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08762
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11045
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1175
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834587
Immune reponse to smallpox (secreted IL-1beta)	GWAS Catalog SNP-Phenotype Associations	1.0	0.295129
BRD-K23326916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3377
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.504
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17976
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975892
BRD-K30625175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13022
BRD-K38966099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0299
BRD-K31614544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09243
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17115
BRD-K77101974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47535
Perturb_10235_KD_EXOC5_SRP187300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4816-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191848
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10767
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.522419
Perturb_14535_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.1876
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948494
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43223
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90336
K562_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0377931
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37959
SKUT1	DepMap CRISPR Gene Dependency	1.0	8.25618
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.849
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.08885
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65538
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	1.4139
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98948
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835932
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260847
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09186
RFX5	ENCODE Transcription Factor Targets	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.284931
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0282722
PMC3022822-1471-2164-12-11-S10.XLS-Suppl_7_newLN229_SOX2_KO_MOCK_2-Unnamed_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56695
Luminal breast carcinoma B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180202
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63683
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB453	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02572
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66712
EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
peripheral vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Leading edge of lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
Breast osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22394
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
BRD-K60454848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12804
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2477
alzheimer disease	GAD Gene-Disease Associations	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8888
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K48389907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93505
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SEM	CCLE Cell Line Gene Expression Profiles	1.0	1.48516
BRD-K65823297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6667
BRD-K46306993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31825
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00732
SISO	DepMap CRISPR Gene Dependency	1.0	3.29562
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.96127
Perturb_6427_KD_TRIM52_SRP126511	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53763
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33098168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17958
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999464
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227707
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13822
BRD-K71742655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05968
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1699
GSE217115_3_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30889
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
K562_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0318597
butyrylcholine-cl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49743
K562_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019381
GD-46-OD81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238213
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87761
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39986
K562_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134915
BRD-K01452910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38337
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2869
BRD-K41026056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05126
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JEG-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60985
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11074
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203654
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intracellular signaling and cell migration supercomplex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
CH157MN	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03445
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04413
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53332
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30599
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7994
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869559
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.4509
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14708
MCAS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
PMC11530610-mmc3.xlsx-WGCNA-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38999
BICR78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874035
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08959
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.1054
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49587
abnormality of circulating protein level	GWASdb SNP-Phenotype Associations	1.0	0.607266
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211441
K562_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0271619
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	3.14662
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76298
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054275
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214297
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962259
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11081
BRD-K29371459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15588
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858337
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93714
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05814
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.38201
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19038
K562_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219123
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07626
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0736
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229146
K562_ZM 447439_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0330231
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU165	DepMap CRISPR Gene Dependency	1.0	2.61316
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209203
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379056
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.794045
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.78285
BRD-K93543569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01915
K562_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252455
K562_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017773
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K02374169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9638
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.06009
UPF 648	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.83
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60708
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.57147
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7972
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.80545
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
SZT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07336
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835056
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884681
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24016
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10895
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65813214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02163
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64437
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999464
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244404
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A07944983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22578
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4343
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43117
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09421
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832466
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225647
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dchs2	GeneRIF Biological Term Annotations	1.0	null
K562_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0300689
K562_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226252
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71234
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48377
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS422	CCLE Cell Line Gene CNV Profiles	1.0	1.75643
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00699
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204487
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5167
U2OS	CCLE Cell Line Gene Expression Profiles	1.0	3.40775
MOLT-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5869
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
K562_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0247401
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59022
K562_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0281305
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17949
hsa-miR-448	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26534
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845432
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860841
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A69097282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15997
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6295312__F1	PFOCR Pathway Figure Associations 2023	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.938923
bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268332
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01248
BRD-A95480808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76813
K562_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0299924
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99929
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72747
MD-73-OU29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20423
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901875
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98586
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15969
biological adhesion	GO Biological Process Annotations 2015	1.0	null
haloperidol-5604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4963-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.976855
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A91891312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96812
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMRC20_KIDNEY	CCLE Cell Line Proteomics	1.0	4.50517
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35509
K562_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0428455
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.811702
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18498
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19081
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46168
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44389
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04739
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232175
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854362
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64698
Perturb_12241_KO_ZMYND8_SRP343066	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.19213
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CAL-33 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72396
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.5
NCIH508	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28243
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65895
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
candidate	GeneRIF Biological Term Annotations	1.0	null
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1595
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K78195641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66197
K562_Thalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225812
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Obatoclax Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226827
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25354
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4189
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262932
PANC-02-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8258
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93488589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18223
all	GWASdb SNP-Phenotype Associations	1.0	0.072272
BRD-K71015709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28365
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39621
Desvenlafaxine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.07
BCPAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77
EW-16	GDSC Cell Line Gene Expression Profiles	1.0	1.92462
GSE208254_4_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34298
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51846
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843451
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
KYSE30	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39826
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78971
acute lymphatic leukemia	GWASdb SNP-Phenotype Associations	1.0	0.49089
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419424
BRD-K99331869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3226
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293608
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858121
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OCILY10	CCLE Cell Line Gene CNV Profiles	1.0	1.66587
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00716
DANG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47462
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0566
K562_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201845
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275429
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90507
K562_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033972
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14723
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22792
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30482
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829698
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.326024
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19868
BRD-K04325154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59671
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.7733
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880453
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259592
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_18482_KD_DNMT1_SRP261597	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.08421
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32758
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.504
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.18184
Integrin alpha8-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60065
Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10852_KO_Smyd3_SRP057101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.47297
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055121
artery disease	GWASdb SNP-Disease Associations	1.0	0.193206
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27515
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.27195
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K32231853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3145
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333627
Schizophrenia, bipolar disorder or major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
K562_Curcumin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019464
K562_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242356
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9139
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16009
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13495
erythrocytes	GAD Gene-Disease Associations	1.0	null
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06448
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4853-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41926
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864064
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.907
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64425
BRD-K37616496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94975
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8984
K562_Daphnetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0221444
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58079
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055121
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.902467
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268293
mepyramine-3184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the coagulation cascade	GWASdb SNP-Phenotype Associations	1.0	0.373524
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GC-40-VJ01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203488
BRD-K52764062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51842
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03802
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.59
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.649
intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01536
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53744
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.01764
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55808
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11173
hsa-miR-578	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-A73618687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4006
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72890304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55952
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3116
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6218
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853531
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.173248
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5971
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187032
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08285
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.017
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
BRD-K80945184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25135
Campomelic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831797
K562_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248098
tenoxicam-4182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212302
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05784
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE37	DepMap CRISPR Gene Dependency	1.0	4.48102
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08521
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61484
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250678
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382621
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045501
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.145553
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0252
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01384
K562	CCLE Cell Line Gene Expression Profiles	1.0	1.64109
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24258
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
CHP134	DepMap CRISPR Gene Dependency	1.0	3.33898
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.803668
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03776
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6375
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6303
CRCGN012_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01866
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558457
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1652
RMGI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17869
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327453
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15085
atherosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_B-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of circulating fibrinogen	GWASdb SNP-Phenotype Associations	1.0	1.54733
Pharyngobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885439
K562_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220205
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226864
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17965
propranolol-6759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Erythrocytes	dbGAP Gene-Trait Associations	1.0	0.702933
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62181
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15391
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.068868
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1125
Fibrinogen, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945018
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63527
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316332
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.22698
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.849997
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	2.08536
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16815_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.06151
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21437
K562_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183368
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054048
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08762
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25679
BRD-K61370861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73859
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396766
K562_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214724
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11465
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06537
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915234
K562_Trametinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230004
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC6070353__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
quinethazone-3793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.302
K562_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196309
K562_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0300287
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
BRD-K00048792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19631
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03219
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12216985-41598_2025_7147_MOESM1_ESM.pdf-40-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.42172
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11544
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-Y97N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204706
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09328
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.172
Brachydactyly type B1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297222
BRD-A99750020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69145
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197781
BRD-K24020784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69115
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.309
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Plasma membrane	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374412
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358054
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0282433
hsa-miR-3144-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
K562_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.024462
K562_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015088
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384849
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8909
LN428	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24908
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K67734449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2151
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516003
Noc4p-Nop14p complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01474
BRD-K61772027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74428
COLO-741	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10921
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
homophilic cell adhesion via plasma membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
K562_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202027
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226085
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76325
BRD-K64075179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87651
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51653
A204	GDSC Cell Line Gene Expression Profiles	1.0	1.49657
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23415
angiogenin-PRI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.29
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Cediranib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022308
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09794
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45268
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A77941182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50432
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63487554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73262
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912293
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
K562_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218652
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26368
BRD-K50045638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17227
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46388
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05863
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14698
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855669
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42391
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.504
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91241
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05746
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3334
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90272
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20076
Multiple Sclerosis	dbGAP Gene-Trait Associations	1.0	0.220667
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	185.437
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83422
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04103
BRD-K44341877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11634
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920021
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.045354
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344688
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K77273085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90183
Perturb_16516_KD_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.0048
BRD-K60430111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08207
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13341
membrane part	GO Cellular Component Annotations 2015	1.0	null
Tubastatin A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92965
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19395
KNS42	CCLE Cell Line Gene Expression Profiles	1.0	1.56128
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05637
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18934
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05759
BRD-K47865468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08501
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Van Maldergem syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.439
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1431
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993433
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
Cranioectodermal dysplasia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RH30	DepMap CRISPR Gene Dependency	1.0	7.38862
K562_AR-42_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179224
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86253
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.235893
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901319
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
proxymetacaine-3113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00732
K562_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0387572
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3679
A375	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62479
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919735
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838362
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38024
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897828
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50908
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564129
PJ34	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.34
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829445
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0271653
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.66825
EZH2	ENCODE Transcription Factor Targets	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40025
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50218
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18341
BRD-K83946740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70111
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254121
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20949
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73313
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93722
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18291
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39955
SPC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14384
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
onset	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226674
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A193-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3447
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25488
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K18447546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67849
K562_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146044
metabolic syndrome x	GWASdb SNP-Disease Associations	1.0	0.706258
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0262316
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06184
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5016
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84449
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.3649
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921713
Perturb_14212_KO_Sp8/Sp8_SRP095936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423673
ESO51	DepMap CRISPR Gene Dependency	1.0	6.56054
Perturb_16813_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25641
BRD-K57497543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42247
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05106
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97705
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15406
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827405
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60769
smallpox	GWASdb SNP-Disease Associations	1.0	1.26953
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36637
BRD-A39031631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79135
BRD-K63984483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27863
Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.83366
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GABPA	ENCODE Transcription Factor Targets	1.0	null
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H596 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
AC-83-LN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209059
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.865813
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04109
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.861562
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875357
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29739
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268101
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.920088
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.029947
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401103
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP50-MEL-B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
K562_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140936
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196811
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60774
K562_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0298919
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39473
SNU182	DepMap CRISPR Gene Dependency	1.0	6.34183
Lipids	dbGAP Gene-Trait Associations	1.0	0.384944
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17358
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33812
BRD-K99250186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07054
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34985
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.105354
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10734
COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.74918
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57163
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1392
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.440105
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06361
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12717
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.52427
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917416
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86812
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
PMC3748736__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867959
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052222
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72335238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21622
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0088
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12754469-ab-25-0159-Supplementary-1.pdf-37-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55327
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-27b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019832
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229658
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04793
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14692
HDLM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29711480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59626
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10917
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K61494613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16933
BRD-K59221664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17397
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62272
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2279	CCLE Cell Line Gene Expression Profiles	1.0	1.53164
K562_Tubastatin A HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181778
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18819
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.36171
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07046
COLO320	CCLE Cell Line Gene Expression Profiles	1.0	1.3838
BRD-K58469385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36403
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clomifene-6648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167025
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17582293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20804
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.94068
K562_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0209579
BRD-K69241192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89177
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52221
Columella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897598
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.811702
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1113
CB-73-HZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282044
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7766
KD	DepMap CRISPR Gene Dependency	1.0	2.6673
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939992
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.30776
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065396
methotrexate-6654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217279
BCATc-In2	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
NCIH2122	DepMap CRISPR Gene Dependency	1.0	2.52803
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281125
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
CTCF	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0206
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957901
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35047
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78395
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3333
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84002
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
GSE148252_2_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cadherin conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Perturb_14504_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.78156
BRD-K08995282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58685
BRD-K59182232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48957
K562_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144618
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54279
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14114
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94393
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15174326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57427
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5111
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.00807
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	2.30614
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.0038
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332056
TP63_01_201	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61372
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909115
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K92246187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21241
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966438
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955862
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_G007-LK_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173184
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911125
BRD-K64221857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41555
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55865
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998347
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22293608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14964
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16673
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855336
BRD-K20016759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39193
K562_Prednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0289065
BRD-K14723547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21618
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00962
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23427
Perturb_9313_KD_HOTAIR_SRP378143	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.47964
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.235594
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23071
K562_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153576
BRD-A57457448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61286
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28507
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_30min_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04512
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08593
SNU1076	DepMap CRISPR Gene Dependency	1.0	4.58153
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58087
K562_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.039033
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8312441__F7	PFOCR Pathway Figure Associations 2024	1.0	null
ovary	HPA Tissue Protein Expression Profiles	1.0	0.811702
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00956
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09144
CRCGN015_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33519
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50529
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65386
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26973
K562_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122105
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912698
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23378
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46862
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190818
K562_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180995
NCI-H522	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14682
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243656
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3867
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43774
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40136
SBC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.47849
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.706258
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00292
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35513
BRD-A61046366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68227
PROKR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44283
BRD-K87878529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10202
K562_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0255518
K562_Raltitrexed_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0290625
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19315
HS-578-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52871
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
DU145	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69487
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99135
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120202
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26836
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206423
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZFX_KD_GSE43021_130_human_NOMO1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
K562_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195741
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29429
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17239
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83765
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28302
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08356
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25734
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51571
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23706
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277475
K029AX	DepMap CRISPR Gene Dependency	1.0	3.29443
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
K562_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0239425
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3374
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013848
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12479
K562_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228933
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206987
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26814
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
TCF4	ChEA Transcription Factor Targets	1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969533
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24472
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0279383
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71916
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6081
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970379
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.18378
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
K562_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220728
Triglycerides	dbGAP Gene-Trait Associations	1.0	0.451307
K562_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172186
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964655
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12002
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200398
K562_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0236718
K562_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209443
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13904
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.691131
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21267
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928016
BRD-K16496140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12465
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33282
middle facial morphology traits (quantitative measurement)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25573
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.733218
abnormality of coagulation	GWASdb SNP-Phenotype Associations	1.0	0.356494
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.101816
PARP	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56153
BRD-K76951235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08611
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
TMED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01255
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97171
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5239-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51271
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02066
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46703
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KL-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dual	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1727
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10966
PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00437
Simpson-Golabi-Behmel syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.22749
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07074
BRD-K60839995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96187
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.880147
DMS-273	GDSC Cell Line Gene Expression Profiles	-1.0	-2.28669
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842586
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75231
K562_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156176
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50381
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.165344
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47356
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
Immune reponse to smallpox (secreted IL-1beta)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
BRD-K07368164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01691
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382969
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00043
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220494
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49932
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06816
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50342
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45315
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Luminal breast carcinoma A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
BRD-K93508241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2406
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
K562_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186332
TEAD4	ENCODE Transcription Factor Targets	1.0	null
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Iniparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020826
Perturb_3009_KD_HNF1alpha/HNF1beta_SRP067843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.5878
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
BRD-K19608864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1492
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14798
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.035658
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.59
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251073
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08561
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29155
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.673
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12077596-NIHMS2076735-supplement-2.xlsx-CRflag_RNA_NONO_TFE3-WT_UP-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24226
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45589340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57003
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47924
BRD-K08939947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57431
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22897
BRD-K58835676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12751
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	GTEx Tissue Gene Expression Profiles	1.0	1.06019
DMS273_LUNG	CCLE Cell Line Proteomics	1.0	3.62982
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57829
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400159
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924502
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48919
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
arteriosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.872896
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494967
BRD-K84586608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0258
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63314
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.58233
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12043227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88229
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08462
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
K562_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0233531
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29846
K562_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168541
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381389
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30469
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966547
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16534
K562_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161628
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33008
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04423
Perturb_5634_KD_FLI1_SRP142503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46431
BRD-K77207661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05213
LN443	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.916
theophylline-2986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BT-20	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245845
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0259083
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34954550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39151
BRD-K80443236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48902
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4531	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2785
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15929
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.93958
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62573
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888131
Bilirubin levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.607009
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66833
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.38661
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854867
BRD-K29338816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65231
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054063
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941518
hsa-miR-3182	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
LDN-192960	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43776
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.178384
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051185
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73656
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4227
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164994
RT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34985
MDAMB453_BREAST	CCLE Cell Line Proteomics	1.0	2.17904
K562_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160334
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW156	DepMap CRISPR Gene Dependency	1.0	4.23534
BRD-K26738018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35992
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63806
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CC-44-MG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294073
PMC3108840__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29143
ZR7530	Achilles Cell Line Gene Essentiality Profiles	1.0	1.77023
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.997643
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
K562_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209468
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	3.35741
K562_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015422
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05705
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11219
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22611
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93665
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K02371763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16564
BRD-K25600773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27161
progesterone-receptor positive breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20737
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827137
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Perturb_8758_KO_SETDB1_SRP141213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.84683
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180982
PMC3108840__F7	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53353
membrane	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57655
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.529113
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903426
GSE239578_5_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0348581
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968458
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Facial morphology traits (63 three-dimensional facial segments)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.73979
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254472
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
K562_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.026229
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04815
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL4054 (USP33)	NURSA Protein Complexes	1.0	null
K562_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161679
K562_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0370862
K562_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181619
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0691
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16869
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03134
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.37498
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31705
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61523
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79468
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22701
K562_PJ34_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0275851
Perturb_2697_KO_ADIPOR1_SRP089784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siTAZ_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3019
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151142
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051707
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04931
K562_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175376
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
BRD-K31203610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09082
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.132
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.8022
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.178384
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47218
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357242
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896989
BRD-K60905563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38087
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K31805261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55961
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01851
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067755
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RMGI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97045
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201419
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90837
K562_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0269155
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258582
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38675
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34186
Pluteus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931792
BRD-K95558029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32279
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04814
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Perturb_442_OE_ONECUT2_SRP115377	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.39793
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
K562_UNC0379_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132563
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36035
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8001
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87076
hypertension	GWASdb SNP-Disease Associations	1.0	0.706258
Lake et al.Science.Ex6_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
Perturb_12688_KD_USP34_SRP150508	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.668
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.088027
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.4392
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15017
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
K562_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234469
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS294T_SKIN	CCLE Cell Line Proteomics	1.0	2.08825
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3545
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11244
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68235
PMC8967065__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47605
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.2344
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871313
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846055
BRD-K75703503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7075
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36102
BRD-K00463125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67432
K562_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219965
hsa-miR-4326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176515
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4316
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.074298
PMC4434585-NIHMS62644-supplement-Supp_Tables.xlsx-Supplementary_Table_13-Supplementary_Table_13_Curated_list_of_mediators_of_Hippo_signaling_along_with_TEAD1_occupancy_and_expression_in_MPCs_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77869064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3731
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213715
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892806
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11897
hsa-miR-618	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3058
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.31677
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055752
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K99859971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42367
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.50543
BRD-K07460436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.327
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00724
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25371
RCHACV	CCLE Cell Line Gene Expression Profiles	1.0	2.25286
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0485517
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901871
K562_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0320312
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221478
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00794
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3059
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36896
KG1C	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03367
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K65725294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75497
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72332
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5847
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357277
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC-1010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.13158
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50148
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45907
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00593
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37994
NCI-H520	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89906
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.99035
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132101
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7754
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94177
Perturb_12702_OE_ERG/FLI1_SRP397680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5014
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
BRD-K42828928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17361
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38385
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50559
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Nintedanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0247866
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63274
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.46091
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00588
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27268
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8996
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0393637
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61611
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04352
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894355
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
snps	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846871
Basal ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
METTL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00932
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6609
K562_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244773
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.17997
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A84923154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32527
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-A71880598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42047
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
SOX2	ChEA Transcription Factor Targets	1.0	null
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50701
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9333
csi	GeneRIF Biological Term Annotations	1.0	null
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75526
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29383520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40197
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05548
K562_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228565
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39965
hsa-miR-27a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26086
BRD-K05417183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17777
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	2.24469
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873701
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35125
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38778
Human - Motor Cortex - Cluster - THEMIS+ LINC00343+ Layer 6 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07868
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01319
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38375
BRD-K83715372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33195
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040432
leukemia	GWASdb SNP-Disease Associations	1.0	0.345986
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05753
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175778
BRD-K35156336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02197
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0302617
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0235
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.158763
K562_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0347068
BRD-K49103536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02273
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22568
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.67876
Chromosome 1q21.1 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32356
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Type 2 diabetes (age of onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
stachydrine-4469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K18620798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45482
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
Amnion epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245958
K562_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0394841
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22803
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.142599
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24619
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30391
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23249
PMC2742312-1479-7364-3-3-221-S3.PDF-107-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885659
K562_Filgotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0307046
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0425
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24864035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71718
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U031	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.388
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964911
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30653
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361332
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02206
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02019
BRD-K19103580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12104
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.90402
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15503
EWS502	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01351
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19561
ritodrine-5680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K09395335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20965
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0276166
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71285
K562_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0292064
EW-7	GDSC Cell Line Gene Expression Profiles	1.0	3.59927
BRD-K89232006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26748
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34178
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47906
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0314122
abnormality of the common coagulation pathway	GWASdb SNP-Phenotype Associations	1.0	1.54733
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4844
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16585
Spermatoproteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
PMC12211054-spectrum.00100-25-s0002.pdf-6-FOXN4_FOXN4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS766T	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0106
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6879-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.36046
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
Alzheimer's disease (age of onset)	GWAS Catalog SNP-Phenotype Associations	1.0	0.266721
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383027
K562_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0371707
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70I-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-325-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.78156
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054702
K562_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171274
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.47588
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909815
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2167
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3948
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0239547
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307537
lipids	GAD Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13042
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.811702
K562_Streptozotocin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0323217
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Pharyngeal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
K562_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0269947
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.088027
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2778
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83833
BRD-A41199690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5077
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15649
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67714
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02761
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11637
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233979
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194744
BRD-K46119789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42552
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.43622
K562_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202978
AM-38	GDSC Cell Line Gene Expression Profiles	1.0	1.4256
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
NOS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56931
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868777
BRD-K28820796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1705
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051842
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24383
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830287
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01188
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
c-reactive protein	GAD Gene-Disease Associations	1.0	null
Cadherin-like	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SSR 69071	DeepCoverMOA Drug Mechanisms of Action	1.0	1.85
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2456
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294252
PMC6295312__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990293
K562_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224666
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08682
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51815
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.550393
GSE71100_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176143
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052104
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07927
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048736
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K82729465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04056
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53683
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936449
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23064
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87093
ES4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50894381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29684
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1169_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321333
K562_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0304312
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19122
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48957
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64173
Adenosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253058
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22645
fads2	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13715
ELF1	ENCODE Transcription Factor Targets	1.0	null
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0699
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0262244
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07636
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833367
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74403
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854803
BRD-K66735566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29796
SW480	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.35833
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72942
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05364
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02171
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82115725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20177
amodiaquine-5747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30794
K562_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136151
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0148
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03875
BRD-K51490301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14591
K562_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134089
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.24194
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.902702
Perturb_2393_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02636
cancer	GWASdb SNP-Disease Associations	1.0	0.594571
K562_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0557476
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20776
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249992
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
lung	HPA Tissue Protein Expression Profiles	1.0	0.811702
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU719	DepMap CRISPR Gene Dependency	1.0	3.82702
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70097
blood pressure	GAD Gene-Disease Associations	1.0	null
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14773
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.5482
BRD-K20278539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.271
BRD-K60743396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96719
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96242
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12775
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
BRD-K62370517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07548
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230612
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59127
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20202
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843278
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.276834
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35877
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320068
MXI1	ENCODE Transcription Factor Targets	1.0	null
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19181
H3K27me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87722624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17776
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0392092
RAD21	ENCODE Transcription Factor Targets	1.0	null
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218675
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063877
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307907
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0299664
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923175
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17191
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2017
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924284
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23717
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYO1	DepMap CRISPR Gene Dependency	1.0	4.63867
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25994
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287539
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464174
BRD-K92910000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15371
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
MRS 2578	DeepCoverMOA Drug Mechanisms of Action	1.0	0.72
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.750915
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283387
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886548
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.81968
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51205
K562_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183715
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0374142
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0154
YD38	DepMap CRISPR Gene Dependency	1.0	4.44077
K562_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0367542
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0280432
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955151
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65414
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	2.51848
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391567
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cyclopenthiazide-4229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04905
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02779
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36237
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76242
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70286
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202009
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04525
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE450_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.24975
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90554
BRD-K27229533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19231
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32529
K562_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0273368
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC0403	DepMap CRISPR Gene Dependency	1.0	2.31331
BRD-K85398599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19968
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19327
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5542
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80707
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477712
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_JQ1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254776
K562_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166168
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0256985
BRD-K98510376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04237
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02169
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992469
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50171760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20828
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82855
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257138
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.98
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168922
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2195
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92864
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169421
K562_A-366_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148506
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.52372
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.798619
LY-294002-5965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08741
K562_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0586735
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243135
PMC9709153__F6	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6705
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278482
age	GeneRIF Biological Term Annotations	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11002
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_ABT-737_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191937
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201085
BRD-K76609014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.781
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42242
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75118
K562_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021622
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40382
NCIN87	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07102
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9893
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87085
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24468
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892651
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K74881104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1781
BRD-A06471483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29173
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.027547
Perturb_10667_OE_PAX3FOXO1_SRP371512	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1824
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17793
BRD-K12930517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35768
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11135
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29389
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06067
BRD-K37942718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11525
Pars tuberalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.504
CRCGN015_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4122
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NN-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60176
Hippo signaling pathway - multiple species	KEGG Pathways 2026	1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827583
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96288607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27053
PMC11530676-41598_2024_77248_MOESM1_ESM.pdf-14-SOX11_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934447
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06991
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
stomach	HPA Tissue Gene Expression Profiles	1.0	1.50505
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16426
CBX3	ENCODE Transcription Factor Targets	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
endometrium	HPA Tissue Gene Expression Profiles	1.0	1.1918
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282044
K562_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0310778
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162415
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45131
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2613
BRD-K16118844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62929
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67843691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37975
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60781
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879147
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05623
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K64559139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04157
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870451
SNU620	DepMap CRISPR Gene Dependency	1.0	6.6662
EW-12	GDSC Cell Line Gene Expression Profiles	1.0	2.0209
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428829
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24467
BRD-K77892972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33122
BRD-K29713418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64198
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34113
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28989
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A204	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10669
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02852
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96064
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16915_KD_Brf1_SRP375944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16411
hyperbilirubinemia	GWASdb SNP-Phenotype Associations	1.0	1.54392
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06106
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830977
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871384
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00491
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232718
BRD-K87131514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70806
Perturb_3822_OE_Hras_SRP342740	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.64288
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87222
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73962
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMUGS_OVARY	CCLE Cell Line Proteomics	1.0	3.10958
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21036
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15129
NCIH716	CCLE Cell Line Gene Expression Profiles	1.0	2.10684
BRD-K13007223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07629
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02805
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163403
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1	ChEA Transcription Factor Targets	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25908
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475127
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0262531
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC1_PANCREAS	CCLE Cell Line Proteomics	1.0	3.34072
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
AD-39-QQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24016
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02092
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1676
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.98929
BRD-K06974027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1724
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213538
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08193
BRD-K79433629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35097
Cadherin	InterPro Predicted Protein Domain Annotations	1.0	null
C-Reactive Protein	dbGAP Gene-Trait Associations	1.0	0.633546
Fibrinogen	GWAS Catalog SNP-Phenotype Associations	1.0	0.696558
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.385805
K562_Lomustine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240933
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11251
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_17679_KO_l2LsL_SRP228817	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999464
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_60_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03886
K562_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165077
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95467
NSC95682	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
UMUC5	DepMap CRISPR Gene Dependency	1.0	2.67468
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957862
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18291
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48495
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.461367
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
IKZF1-21737484-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27125
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38017028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14265
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_4237_OE_ERG/FLI1_SRP403488	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.46983
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
K562_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0307944
K562_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166182
LN382	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00976
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Amnion epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255428
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5817
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93105
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0340405
BRD-K33044659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07284
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.139
cation binding	GO Molecular Function Annotations 2015	1.0	null
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0443
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30627
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06141
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4109
MHHCALL3	CCLE Cell Line Gene Expression Profiles	1.0	1.817
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05372
MITF_01_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59144
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929882
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.963698
BRD-K12260863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18134
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03331
BRD-K77541177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00484
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU46	DepMap CRISPR Gene Dependency	1.0	3.73868
K562_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0333109
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3289
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0492
CPC-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.124798
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_8759_KO_SETDB1_SRP141213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.16596
GSE210476_11_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06398048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42138
K562_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162839
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.567786
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-69-TQ80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264922
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03418
AMO1	DepMap CRISPR Gene Dependency	1.0	2.76247
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847673
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-3.23955
K562_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171768
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199233
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274021
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11558691-tables5_bbae592.xlsx-SOX17-Genes_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A26640795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28804
MEC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54715
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945018
K562_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0548094
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6439
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0413575
BC-43-PD20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273846
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44338
CRCGN017_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03134
K562_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.044843
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56512
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272696
BFTC905	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84583
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47998
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7866-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201297
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65247
AA-56-QO38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282148
K562_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0379183
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07668
Perturb_14094_KD_HDAC7_SRP199194	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.12879
BRD-K76691746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05382
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3323-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22312
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159591
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63019
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84426
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
CRCGN016_MCF10A.TP53.M_24H:N24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02959
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15895
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0544
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27638
JUN	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918009
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29482
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8642
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4518
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19791
GSE220520_6_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44005
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847444
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
Torcetrapib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.49
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K63754039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71855
K562_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130721
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873701
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0294759
hsa-miR-1233	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.734583
K562_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254051
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
K562_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0245697
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401233
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055741
BRD-K98431828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27043
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41529
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834333
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11818
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11818
Perturb_1170_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GATA2	ChEA Transcription Factor Targets	1.0	null
fluorometholone-5771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06518
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849637
K562_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218265
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68321
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54072
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91643
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
M059J	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39314
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884971
Fibrinogen	dbGAP Gene-Trait Associations	1.0	1.0562
BRD-K75410936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35631
PANC0327	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27362
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288592
IKZF1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982533
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250711
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6291
K562_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0470554
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34905
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18556
Perturb_8464_OE_C2_SRP242584	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-A52510783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78256
CCC5	DepMap CRISPR Gene Dependency	1.0	2.29793
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52279
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
phthalylsulfathiazole-3033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856222
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thus	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-101	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06378
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952322
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923345
MYCN	ChEA Transcription Factor Targets	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.762027
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K84457681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55937
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56451
Perturb_2963_KD_Nap1l2_SRP304879	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.96001
Perturb_4723_KD_Npas4_SRP166456	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29174
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93404
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165266
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69027
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18965
LCLC-97TM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0249
K562_Anacardic Acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193106
Calcium	HMDB Metabolites of Enzymes	1.0	null
KOSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.97143
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3751
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.792
roles	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7105
SUZ12	ENCODE Transcription Factor Targets	1.0	null
BRD-K77399094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33547
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K95712112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09045
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K25842662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86908
BRD-K97721960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2141
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
triglycerides	GAD Gene-Disease Associations	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052208
K562_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0236259
TUHR4TKB_KIDNEY	CCLE Cell Line Proteomics	1.0	3.10958
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0371194
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187742
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.1756
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9287
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86531
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03413
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24056
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207988
MEL270	DepMap CRISPR Gene Dependency	1.0	10.877
BRD-K27347421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30912
K562_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0433039
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90298
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0262428
tobramycin-4162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12054
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12679
K562_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159339
BRD-K23361743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83052
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0329558
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40277
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07111
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11895
BRD-K76088420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42728
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18944
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6418
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458325
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.85839
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97993
CRCGN017_MCF10A.WT.HP_24H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0669
BRD-K46293468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08765
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lipoproteins	GAD Gene-Disease Associations	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201217_2_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00087
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47826
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48231
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865201
GSK343	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053788
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39695
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52925
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.025891
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832988
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K17553044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04899
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.376134
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0276061
tauopathy	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212693
BRD-K68595406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23555
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27816
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04423
BRD-K22280519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29662
OAW42	DepMap CRISPR Gene Dependency	1.0	3.92916
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00138
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199147
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12032
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mild Cognitive Disorder	DisGeNET Gene-Disease Associations	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72029544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2109
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77118
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05734
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.45023
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_ABT-737_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0327458
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08781
K562_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0221345
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4848-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2142_KO_ASCC2_SRP282634	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN014_HEPG2_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0627
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930752
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03898
spleen_3d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.835436
BRD-K47999752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48726
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59391
DMS-114	COSMIC Cell Line Gene Mutation Profiles	1.0	null
males	GeneRIF Biological Term Annotations	1.0	null
acute leukemia	GWASdb SNP-Disease Associations	1.0	0.576591
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18466
HEPG2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52752
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.19738
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.916044
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39923
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220363
K562_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019937
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6036
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919063
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.505377
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185938
K562_Baricitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210722
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0824
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637144
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.44888
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.0224
K562_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0320383
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18291
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87185
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.360902
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15605
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adult pineal parenchymal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
K562_Selisistat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188011
Anacetrapib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051931
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0763
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95409
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
u87	HPA Cell Line Gene Expression Profiles	1.0	0.867976
K562_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225815
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.757
SIMA	GDSC Cell Line Gene Expression Profiles	1.0	1.53692
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148889
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wing disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
BRD-K89376690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25507
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36856
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944863
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83483
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18946
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08815
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0361816
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1658
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1918
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.421915
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85658
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59861
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92453
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4148
K562_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226655
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253062
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A02214146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10972
BRD-A57594599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31541
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12021
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.43072
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17092
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271093
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
K562_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.027734
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.347128
K562_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0256585
cyclizine-5100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84401063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1348
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
BRD-K93008833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21303
BRD-K61491580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68192
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40806
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63207
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67762
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01045
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070857
GSE153923_1_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.41385
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919508
BRD-K81932943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31967
COPS5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017338
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65549
HJC0350	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210871
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27050140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34627
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.39024
BRD-K15047839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08289
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248287
alvimopan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26269
U-2-OS	GDSC Cell Line Gene Expression Profiles	1.0	1.85976
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.674512
Perturb_4220_KO_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.44472
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10483
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4803-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272383
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0751
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
BRD-K10146653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52096
BRD-K20624967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59929
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25961
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.40265
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28769
PANC-10-05	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5092
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyrotoxic Periodic Paralysis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K62536891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94103
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48901
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08155
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.852
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.854384
HN-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00379
Cytokine Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0456
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79773
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
K562_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151785
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0279471
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365354
K562_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202594
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390403
BRD-K81952048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15154
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227406
K562_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144739
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.996384
BRD-K95148987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44124
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-2.4025
Breast leiomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.752879
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibrinogen	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09053
BRD-K13941175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12641
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69908
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843839
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5383
MOGGUVW	CCLE Cell Line Gene CNV Profiles	1.0	1.38377
BRD-K33757887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1892
EW-1	GDSC Cell Line Gene Expression Profiles	1.0	2.47158
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5776
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18616
BRD-K35792251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14553
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29403
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.733218
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
K562_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154026
Perturb_9075_KD_lncHypERr_SRP095640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04521
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49637
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32146
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3748736__F1	PFOCR Pathway Figure Associations 2023	1.0	null
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49189
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35758
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12718
BRD-K39597125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02608
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38204
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.38377
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46743
BRD-A39193201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44316
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93396907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12058
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.811702
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K45592944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00117
BRD-K31526203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39032
KY821	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K99873441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76105
K562_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0247817
K562_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0276017
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02211
bemegride-3051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57270624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44657
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44738
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0936
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34938
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0245691
K562_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223448
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.119894
BRD-A98795688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62598
CD-97-ZV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295115
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08885
K562_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0297886
BRD-K94109423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44082
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880427
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890902
alzheimer's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
valproic acid-5574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K31889353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07636
EW-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26032
HCC2218	Achilles Cell Line Gene Essentiality Profiles	1.0	2.27722
dementia	GWASdb SNP-Disease Associations	1.0	0.446685
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.55633
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07203
BRD-K67666705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34159
acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.458803
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37341
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95159