association dataset threshold value standardized value Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PACS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06337 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74609 USP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71062 SRSF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06456 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX19B Hub Proteins Protein-Protein Interactions 1.0 null Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.2866 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46D-01A-21R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M9-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198380_0_v_1_phgdh_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VR-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JAK2_mutant_40_GSE11003 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.72406 peptidase activity GO Molecular Function Annotations 2015 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_6949_KO_Rbm20_SRP328560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.78838 ZCCHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99069 Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null yap1_18413746_mcf10a_gof_human_gpl570_gds3220 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.708524 hsa-miR-676 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 hsa-miR-764 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ZDBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61645 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100393_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08957 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160053 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PDCD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71534 CMG complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.371 FBXO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16476 protein catabolic process GO Biological Process Annotations 2025 1.0 null Huntington's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3907 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21196 RERFLCAD2 DepMap CRISPR Gene Dependency 1.0 3.29902 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null catalytic complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057322 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null KS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC2423434__F5 PFOCR Pathway Figure Associations 2023 1.0 null colon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.102 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16976 Lung adenocarcinoma_LUAD_TCGA-78-7162-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3908 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 496100404_PCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.76369 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8396 ODR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00772 adult retina HPM Cell Type and Tissue Protein Expression Profiles -1.0 -1.17459 ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.933364 EJM DepMap CRISPR Gene Dependency 1.0 3.76507 LSM1 Hub Proteins Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.33005 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.75 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66538 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5307 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ubiquitin-like InterPro Predicted Protein Domain Annotations 1.0 null MEL-HO COSMIC Cell Line Gene Mutation Profiles 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.66776 hsa-miR-3691-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Multiple epiphyseal dysplasia 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.8889 ZBTB45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17395 hsa-miR-16 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 SRSF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06007 LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.53687 Whipple's Disease_macrophage_GSE16180 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.57879 proteasomal protein catabolic process GO Biological Process Annotations 2023 1.0 null NCI-H82 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.13607 REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Null cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83505 ZSWIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60299 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14529 hsa-miR-490-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.606916 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3558 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0983 Gut TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 extrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.136087 CLDN9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79478 SW1271 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 Schizont TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 response to hydroxyurea GO Biological Process Annotations 2025 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 cell culture TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 H3K9me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.027321 KIT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97601 496100556_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00031 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878373 SCRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52449 orbital frontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03088 nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Ubiquitin activating enzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.786 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HOXB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4231 LOXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43 G-401 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.575 Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_4_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8391 Proteasome storage granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.092 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 Prostate adenocarcinoma_PRAD_TCGA-VN-A88P-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10663 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42576 CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 3.70341 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MYC ChEA Transcription Factor Targets 1.0 null REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CI1 CCLE Cell Line Gene Expression Profiles 1.0 2.23834 REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Spermatoproteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.238 Perturb_13134_KO_Pnpt1_SRP134850 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.52199 Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ribonuclease H2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.759 MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null epididymis HPA Tissue Protein Expression Profiles 1.0 1.08526 SKMEL31 CCLE Cell Line Gene CNV Profiles -1.0 -2.55732 CERS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2097 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26377 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22679 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.20232 PAXX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36064 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06568 Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37986 CHST15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03008 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.855485 FLI1 ChEA Transcription Factor Targets 1.0 null aspartic-type peptidase activity GO Molecular Function Annotations 2015 1.0 null TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9913 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 hsa-miR-4770 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Blood plasma TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 GSE202434,GSE202438_2_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null OSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30401 TP63 ChEA Transcription Factor Targets 1.0 null SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7514 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914606 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 1.19459 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5324 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null MAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38198 culture condition:cd4+ cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 macrophage BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.343 SNU520 CCLE Cell Line Gene Expression Profiles -1.0 -2.6312 Myeloid neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 ELK1 ChEA Transcription Factor Targets 1.0 null DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25274 A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 4.17108 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21196 Proteasome regulatory particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.372 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.516532 hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4244 biological_process GO Biological Process Annotations 2015 1.0 null H3K36me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.3496 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878373 GSE202434,GSE202438_10_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83505 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.983434 ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ADCY9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51073 pb1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.435 Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7212 IKZF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22616 MKNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89495 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8943 bone marrow cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.994266 hsa-miR-1184 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.834829 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KP2 DepMap CRISPR Gene Dependency 1.0 2.45051 NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -1.65793 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.35689 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.11446 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.704395 hsa-miR-324-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE246716_0_v_1_trappc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PCYT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41208 GSE63048_11_v_6_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.767 Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null Perturb_4849_KD_ZEB2_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.7789 hsa-miR-589 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5177 Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2272 RERFLCAD2 CCLE Cell Line Gene CNV Profiles 1.0 1.89357 BXPC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GALK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31622 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6018 Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.7084 monocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 KLF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09207 YKT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61958 NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.35361 Ubiquitin-related domain InterPro Predicted Protein Domain Annotations 1.0 null hsa-miR-3945 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1056 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null A-CA-04-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.51354 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.5549 FBXO10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61347 AKT1_OE_GDS2308_499_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE168596_1_v_3_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EKVX CCLE Cell Line Gene CNV Profiles 1.0 1.9924 Promastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.057 leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.017272 hydrolase activity GO Molecular Function Annotations 2015 1.0 null SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.918373 H2AK5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-936 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06652 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.473 Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.524 Central Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null Proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.563 CAPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06757 L-363 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.691 Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88123 GSE210770_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 OTUD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14525 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83505 FAHD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41127 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.4308 496100435_TCx_probable Alzheimer's disease_TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.96844 CWF19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06342 Cytosolic proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.422 KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sense organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0807 NMCG1 CCLE Cell Line Gene Expression Profiles -1.0 -3.02626 GSE150669_2_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null JHU-022 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 Cco TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.108 side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.136087 Reservosome lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.74 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastric cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.803 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94196 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.95221 ARGLU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17048 DCAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02689 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX1 ChEA Transcription Factor Targets 1.0 null KRAP_Deficiency_GDS3528_564_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_4876_KD_BANCR_SRP135857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.66097 FLI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Amyotrophic lateral sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.314 Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7902 POLQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85922 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NL-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1271 CCLE Cell Line Gene CNV Profiles 1.0 1.73911 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.473 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25296 GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null NUGC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.96479 OCIM2 DepMap CRISPR Gene Dependency 1.0 2.29388 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0075 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01385 GSE202434,GSE202438_9_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGPAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80033 cytoplasmic side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160053 C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05957 NCIH2085 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.841439 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2809 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.382508 NCI-H1993 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 VWA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74649 hsa-miR-1245b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Endopeptidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.534 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.25768 5637 CCLE Cell Line Gene CNV Profiles 1.0 1.40292 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.168381 Ciliary pocket COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.718 B-lymphoblastoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.805 KPNRTBM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.88795 ZNF430 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50475 GSE220600_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNUC5 CCLE Cell Line Gene Expression Profiles -1.0 -1.51809 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.841439 hsa-miR-4735-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 KATOIII CCLE Cell Line Gene CNV Profiles 1.0 1.37679 PMC3715494__F2 PFOCR Pathway Figure Associations 2024 1.0 null Mononuclear phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03856 SNU410 CCLE Cell Line Gene Expression Profiles 1.0 1.88778 intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 BLOC1S6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91553 Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF2 Hub Proteins Protein-Protein Interactions 1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.884115 phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Large cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.714 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893341 GAL3ST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20009 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924508 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240027,GSE240030_5_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.764 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.527 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.005 cellular response to nitrogen compound GO Biological Process Annotations 2025 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53847 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08166 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4612 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.67045 hsa-miR-1207-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 hsa-miR-4469 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.334733 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6224 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.76496 AFTPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10443 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72024 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.841439 adult stem cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 DU4475 CCLE Cell Line Gene CNV Profiles -1.0 -1.33119 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19502 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4507 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 SMAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6088 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL54 CCLE Cell Line Gene Expression Profiles -1.0 -1.55924 INHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.63332 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98611 Lung adenocarcinoma_LUAD_TCGA-55-7907-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2825-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1196 CCLE Cell Line Gene CNV Profiles -1.0 -1.75178 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Median arcuate ligament syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.137 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29791 KYSE-270 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979861 Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4093 RL CCLE Cell Line Gene Expression Profiles 1.0 2.32522 EFM19 CCLE Cell Line Gene Expression Profiles 1.0 1.54915 proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.885628 PE/CA-PJ15 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100318_PCx_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24193 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.914104 Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spindle pole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.239916 Multiple myeloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.316 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.12955 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68294 Lung adenocarcinoma_LUAD_TCGA-05-4405-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCUM1 DepMap CRISPR Gene Dependency 1.0 2.63525 primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825809 AOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04487 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.241438 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55059 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6474 CLN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.12741 PMC6568242__F2 PFOCR Pathway Figure Associations 2024 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.129 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.396 Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01616 nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.089579 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-4317 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 hsa-miR-4251 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.958586 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914606 peptidase activity, acting on l-amino acid peptides GO Molecular Function Annotations 2015 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.761343 gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091762 ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.638434 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12009 Multiple myeloma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.113 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979861 Perturb_10623_OE_Vcp_SRP214099 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.32602 Hyphal tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.764 NCIH1618 CCLE Cell Line Gene Expression Profiles -1.0 -1.81462 response to hydroxyurea GO Biological Process Annotations 2023 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6514 mononuclear cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CEP72 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05569 Perturb_13927_OE_ESRRG_SRP363188 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.93348 hsa-miR-3126-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41438 Perturb_8400_KD_Srrm2_SRP195765 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.29523 A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.70704 Perturb_14483_KO_Figla_SRP228490 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.33329 GSE171352_2_v_3_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-CoV MA15_Day4_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.03023 TIA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42744 REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7745 KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85926 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.89422 Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.60447 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null PF-382 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.54104 H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5508-01A-02R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32478 ISL1-27105846-CHIP-SEQ-CPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RBL1_KO_GDS1932_739_mouse_Neurospheres GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.86485 orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06216 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21236 GSE232472_1_v_2_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null EHEB CCLE Cell Line Gene Expression Profiles 1.0 1.52123 NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.4866 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912458 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848855 Body wall muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.08 SPRED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54638 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.00565 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.361 Mre11 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.223 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.985834 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15321 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9208 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.5576 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.989674 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 molecular_function GO Molecular Function Annotations 2015 1.0 null Frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 MIEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40394 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7473 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.86744 GSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19873 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.37951 CTCF ENCODE Transcription Factor Targets 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PDXP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2125 TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02829 thyroid gland HPA Tissue Protein Expression Profiles 1.0 1.08526 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72181 Food vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.161 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_17279_KO_Mlx_SRP303876 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.492 GSE190316,GSE190324_10_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.1431 OCILY10 CCLE Cell Line Gene CNV Profiles 1.0 1.74171 LUBAC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.684 OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4576 Perturb_5143_KO_Ring1B_ERP008873 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.7304 SCF ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.389 CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47385 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869311 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041463 GSE213442_1_v_0_kpna2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ILRUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15494 GINS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.669 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GI1 CCLE Cell Line Gene Expression Profiles 1.0 1.45459 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3876 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914072 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null pioglitazone_mus musculus_gpl2897_gse8806 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22679 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242672 protein metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_16887_KO_lrrk2_SRP252711 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.38892 PMC12290085-44276_2025_158_MOESM1_ESM.pdf-1-BNC2_BNC2 Rummagene Transcription Factor Associations 2026 1.0 null OCIM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.24858 CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944609 organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.215314 CBX2_KO_GDS4445_353_mouse_E11.5 XX embryonic gonads GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null A375 COSMIC Cell Line Gene Mutation Profiles 1.0 null BNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78836 FIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87066 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12072 Childhood germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.737 Spore wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.611 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HAP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.793 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924508 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Invertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.941 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8943 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP1AR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92057 hsa-miR-223 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869311 Adrenocortical carcinoma_ACC_TCGA-OR-A5K8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL5 CCLE Cell Line Gene Expression Profiles 1.0 1.45812 hsa-miR-320e TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ARMCX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22124 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5169 Rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Encysting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.677 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26377 Blood TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -2.03596 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL-148 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1913 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.989928 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.07486 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MBOAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15992 Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03024 Perturb_8399_KD_Srrm2_SRP195765 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.56131 CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spinal cord TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 extrinsic component of cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160053 DVL2 Pathway Commons Protein-Protein Interactions 1.0 null MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1997 Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26462 L-540 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.274 pancreatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.458241 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824948 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PNMA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48356 PALM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15885 PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90098 SH10TC CCLE Cell Line Gene Expression Profiles 1.0 1.48157 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33175 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1954 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 Mononuclear cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 microtubule organizing center COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.105869 KARPAS422 CCLE Cell Line Gene CNV Profiles 1.0 1.73394 ANKS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.32524 Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G-292_CLONE_A141B1 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08166 hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Prostate adenocarcinoma_PRAD_TCGA-G9-6333-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFM-223 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE144838_4_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050865 TCIRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60988 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9594 REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2312 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12072 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29482 HUPT3 CCLE Cell Line Gene Expression Profiles 1.0 1.46412 transferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063397 Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCL28 Pathway Commons Protein-Protein Interactions 1.0 null CCDC25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74537 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.35114 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85377 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2110 DepMap CRISPR Gene Dependency 1.0 3.25959 SAMD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19323 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6414 PGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47798 SLR21 CCLE Cell Line Gene CNV Profiles -1.0 -1.41477 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUSP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57228 Digestive cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.593 PCI-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -1.97272 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50596 TRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4896 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.285086 AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.791921 Kenny-Caffey syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.672 cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 HEK-293F cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.558 embryo TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 KARPAS422 CCLE Cell Line Gene Expression Profiles 1.0 1.75252 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.05142 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GR MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-4276 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH7 DepMap CRISPR Gene Dependency 1.0 3.04853 spindle pole body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.391228 Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 2.07743 TTC32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89846 Edema HuGE Navigator Gene-Phenotype Associations 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2095 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29482 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TestisLeydigCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.21078 bone BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07369 hsa-miR-374b TargetScan Predicted Conserved microRNA Targets 1.0 0.09606 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUM149PT DepMap CRISPR Gene Dependency 1.0 4.00229 L-540 COSMIC Cell Line Gene Mutation Profiles 1.0 null B4GALT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51999 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.8815 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5427 ZFP37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48938 TMCO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46299 MIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6094 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24788 SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.32484 LMSU DepMap CRISPR Gene Dependency 1.0 22.0303 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8446 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.4068 BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null NUTM2G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81634 Lung adenocarcinoma_LUAD_TCGA-NJ-A55O-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHP126 CCLE Cell Line Gene CNV Profiles -1.0 -1.51895 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DDX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30875 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NT5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22265 H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 hsa-miR-195 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.24945 UMUC9 DepMap CRISPR Gene Dependency 1.0 2.32993 HNF4G JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2118 rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 YD10B CCLE Cell Line Gene Expression Profiles -1.0 -1.54705 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869311 CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1155 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.25809 metabolic process GO Biological Process Annotations 2015 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.24126 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.38846 primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.982328 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.95415 Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1260 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Reservosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.336 glutamate-cysteine ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.719 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6815 REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE4 CCLE Cell Line Gene CNV Profiles -1.0 -1.40492 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80931 Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00634 Ruijs-Aalfs syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.538 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm individualization complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.73 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 GSE240027,GSE240030_5_v_2_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4527 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 NCCIT Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.03341 ELF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1691 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65F-01A-21R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.40875 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLHL42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98863 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.83774 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.58445 496100499_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56048 hsa-miR-4753-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.248923 BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68098 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE101537_1_v_3_neurog3_mouse RummaGEO Gene Perturbation Signatures -1.0 null INMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27823 Perturb_4848_KD_NKX25_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.39765 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894265 EKVX COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 59M CCLE Cell Line Gene Expression Profiles -1.0 -1.65368 Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3142 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ERLEC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63428 Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null 22RV1 DepMap CRISPR Gene Dependency 1.0 3.75604 hsa-miR-4768-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Perturb_12604_KO_Cbx3_SRP212056 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.70533 Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.4659 DPEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63158 HL-7702 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 Asthma_Epithelial Cell_GSE4302 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.65959 METTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96023 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1979 Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN229 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 WDCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45193 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.40274 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPARD ChEA Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A5-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATP5MC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58589 respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9717 PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-3940-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914072 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2368 ALG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06482 WM983B CCLE Cell Line Gene CNV Profiles -1.0 -1.71133 cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78955 POLR2A ENCODE Transcription Factor Targets 1.0 null HBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60802 H3K9me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 NOSIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58368 Eukaryotic translation initiation factor 3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.99 penta-snRNP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.798 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54565 Rectum adenocarcinoma_READ_TCGA-AF-2693-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNA replication preinitiation complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.269 NDUFS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38609 TXNDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01372 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01807 hsa-miR-607 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 Spinocerebellar ataxia with axonal neuropathy 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 binding GO Molecular Function Annotations 2015 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.974956 myeloid progenitor cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERFGC1B DepMap CRISPR Gene Dependency 1.0 2.58404 MFE296 DepMap CRISPR Gene Dependency 1.0 8.98192 INSIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95879 GSE210383_0_v_1_trim71_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIRT4_KO_GDS4823_22_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01616 TFAP2A ChEA Transcription Factor Targets 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.923077 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fetus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.391228 megakaryoblast TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 ATG4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28079 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13329 JEG-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2941 MTCH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.29368 ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Bone marrow disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01616 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.7264 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.96084 Lung adenocarcinoma_LUAD_TCGA-55-7911-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Cytoplasmic ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 TMEM140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27842 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29353 PAXBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29127 MET_knockout_251_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.74565 RWDD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45785 stomach HPA Tissue Protein Expression Profiles 1.0 0.707482 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mating projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.982 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4691 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.032174 LMSU CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.983434 GSE150669_0_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-1080 COSMIC Cell Line Gene Mutation Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.982466 hsa-miR-620 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE89018_11_v_8_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3-3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95405 Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Cytostome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.505 hsa-miR-4768-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03391 Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChaGo-K-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.742 excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JHOM1 CCLE Cell Line Gene CNV Profiles 1.0 2.11081 Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.473 NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 1.64173 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.919236 Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 ER ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.192 culture condition TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-494 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.891566 DUS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52379 SKRC20 DepMap CRISPR Gene Dependency 1.0 3.22565 brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 ATG12 Hub Proteins Protein-Protein Interactions 1.0 null TEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70206 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9443 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0807 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8021 GSE158431_5_v_1_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 FGF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23691 male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1056 gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 L428 CCLE Cell Line Gene CNV Profiles -1.0 -1.55231 GSE201042_6_v_0_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NB13 DepMap CRISPR Gene Dependency 1.0 2.76166 hsa-miR-15b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 septal organ BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.25482 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49166 RAJI CCLE Cell Line Gene Expression Profiles 1.0 2.59018 Dorsal nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.231 ESR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68699 Endopeptidase Clp complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.803 Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RC-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4981_KO_Kmt2d_SRP107208 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.821 Monocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5409 Protein N-acetylglucosaminyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.687 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.841439 hsa-miR-548c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72181 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.80631 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944609 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 blast cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 hsa-miR-1260b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HCC-44 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMEM14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77881 IDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67982 PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.906445 all GWASdb SNP-Phenotype Associations 1.0 0.030222 SCF-Skp2 ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.001 CAB39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76903 H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4722-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62978 KYSE-150 COSMIC Cell Line Gene Mutation Profiles 1.0 null CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE201042_6_v_4_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GLT8D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00416 KDM5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29246 PHLDA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59752 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1909 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Multiple epiphyseal dysplasia due to collagen 9 anomaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.523 TCTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85352 Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skeletalmuscle BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.862951 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.77228 KARPAS-422 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052361 STBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78429 proteolysis involved in protein catabolic process GO Biological Process Annotations 2025 1.0 null SK-GT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SCNN1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35832 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.836267 Trypanosomoid form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073 ZIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86119 Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.507 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM127 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75062 Eye TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Replication fork COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.574 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null OTX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.815 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16756 placenta TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44451 Lung adenocarcinoma_LUAD_TCGA-55-8511-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BCL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77914 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5397 bone marrow HPA Tissue Protein Expression Profiles 1.0 1.08526 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0544 SNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1185 hsa-miR-150 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 E2F1 ChEA Transcription Factor Targets 1.0 null H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3144-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Prostate adenocarcinoma_PRAD_TCGA-G9-6353-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57587 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59213 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.27435 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.85279 hsa-miR-4657 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.884115 ME1 CCLE Cell Line Gene CNV Profiles 1.0 1.55011 ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null extrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.113627 ARH-77 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.32 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.8314 Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226316_11_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TRAM1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14098 Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13055 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -1.74571 GSE201042_6_v_7_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5839 Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94223 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25291 Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64442 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null human immunodeficiency virus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.605762 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE228894_0_v_2_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83505 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20565 ventrolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49407 H3K9me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0256 SEC61A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81406 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040384 Aspartic peptidase, DDI1-type InterPro Predicted Protein Domain Annotations 1.0 null 496100564_TCx_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15014 SK-LU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03494 PMC7022656__F9 PFOCR Pathway Figure Associations 2024 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7375 Large granular lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.953691 SLC1A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02413 Natural killer cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE143316_0_v_6_somatostatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null KYAE-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HT-1376 COSMIC Cell Line Gene Mutation Profiles 1.0 null MPV17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68554 SKGII DepMap CRISPR Gene Dependency 1.0 2.70493 MICAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76119 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.19151 H3K9me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06568 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.313 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO775 CCLE Cell Line Gene CNV Profiles -1.0 -1.45443 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10532 TFAP2A-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1202 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 hsa-miR-875-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU886 CCLE Cell Line Gene CNV Profiles -1.0 -1.58711 PAPOLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84448 REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48028 hsa-miR-4491 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 mononuclear phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CFAP126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90657 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8968 COLO678 DepMap CRISPR Gene Dependency 1.0 3.20036 E2F1-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1763 Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9964 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7841 PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GOSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05725 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DETROIT562 CCLE Cell Line Gene CNV Profiles 1.0 2.07174 marrow cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6972 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.01945 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 53.4553 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48132 proteolysis GO Biological Process Annotations 2015 1.0 null endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.055266 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35213 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951721 Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE125025_2_v_3_lyl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_10265_KO_Smad3_SRP040560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.41808 KP-1N COSMIC Cell Line Gene Mutation Profiles 1.0 null TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25296 GSE166004_1_v_0_pld1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hrd1p ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.302 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.23847 integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.160948 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66425 hsa-miR-4761-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 cellular response to hydroxyurea GO Biological Process Annotations 2025 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null MHCC97-L cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.587 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCILY10 CCLE Cell Line Gene Expression Profiles 1.0 1.52234 UFD1-NPL4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.701 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2854 Xeroderma pigmentosum DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 GSE132759_4_v_0_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01382 ONS76 CCLE Cell Line Gene CNV Profiles -1.0 -2.26739 SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EW7 DepMap CRISPR Gene Dependency 1.0 2.89795 U2OS DepMap CRISPR Gene Dependency 1.0 2.12874 Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAS Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.42412 OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6356 JHU022 DepMap CRISPR Gene Dependency 1.0 2.80307 vegetative cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.664775 496100357_TCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.75662 large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Trypomastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null proteolysis involved in protein catabolic process GO Biological Process Annotations 2023 1.0 null FOXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16462 WSU-DLCL2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.0375 PAN complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.291 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37391 hsa-miR-1261 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09832 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.949127 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20493 HSPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48875 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null exanthem DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.642615 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1849 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29489 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.548 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01988 NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 TXNDC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83454 H3K9me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KP2 CCLE Cell Line Gene Expression Profiles -1.0 -2.15299 GSE198054,GSE198057_0_v_1_csf1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.0 Lymphoid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Oligosaccharyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.095 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28513 HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979861 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1056 D-336MG COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A702-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 1.08526 Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4638-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041343 Perturb_11167_KO_Tsc1|Pten_SRP156216 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.0937 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.002 hsa-miR-512-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 ES8 COSMIC Cell Line Gene Mutation Profiles 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86553 TP53_01_68 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60198 Lung adenocarcinoma_LUAD_TCGA-44-6776-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211177,GSE211178_9_v_1_ets1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU1033 DepMap CRISPR Gene Dependency 1.0 2.82279 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3829 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE89018_1_v_2_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -1.53836 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.8088 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.437 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0941 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33054 NUDCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88885 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 117.094 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 74.9891 MRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67887 ARPC5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00981 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147662_0_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null scf ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.86123 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51031 Brain Lower Grade Glioma_LGG_TCGA-DU-8166-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCSK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31487 NCI-H211 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6342-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GAS2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81719 SYT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9831 DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular response to inorganic substance GO Biological Process Annotations 2023 1.0 null hsa-miR-374a TargetScan Predicted Conserved microRNA Targets 1.0 0.103424 Pupa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.746 REST_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.99926 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.937928 DAN-G Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.2255 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE94849_1_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.18115 ADAMTS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25943 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.505944 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.362 REST ENCODE Transcription Factor Targets 1.0 null RGS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85705 blood plasma TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Kenny-Caffey syndrome type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.036 telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100428_TCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40016 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null placenta BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959089 hsa-miR-4473 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Proteasome accessory complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.32 CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Glaucoma_Retina_GSE3554 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.91717 Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE157592_1_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51428 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.1604 Phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Mantle cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.204 EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01385 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71428 hsa-miR-885-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.029 forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 B-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 DAUDI CCLE Cell Line Gene Expression Profiles 1.0 1.78334 hippocampus (hippocampal formation)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842276 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.16199 Replisome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.467 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.22241 lung TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F1-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null AKT1_OE_GDS2308_498_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7774 PMC10290283-biol-2022-0622-sm3.pdf-341-EGR2_EGR2 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTBP2-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.314 WDR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84958 protein catabolic process GO Biological Process Annotations 2023 1.0 null Heart disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.473 hsa-miR-2355-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53847 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Proteasome activator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.812 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.334733 ASCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43215 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.45 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.952566 ZC4H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18487 496100399_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26758 SPSB1 Hub Proteins Protein-Protein Interactions 1.0 null CARMIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51432 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914606 hsa-miR-4768-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.982328 hsa-miR-2467-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 U-CH2 COSMIC Cell Line Gene Mutation Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53847 Paw TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.899 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23222 Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00365 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00365 hsa-miR-3925-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 NECTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15783 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2629 adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Peptidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.506 Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2A-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6316 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 cls1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 hsa-miR-3647-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18596 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7375 SERINC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59355 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06568 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 H4C3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27793 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59282 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Aggresome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.213 ISTMES1 CCLE Cell Line Gene Expression Profiles 1.0 1.70288 KDM5A ENCODE Transcription Factor Targets 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.923 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.113 SCC15 CCLE Cell Line Gene CNV Profiles 1.0 2.45891 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43482 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25296 FLI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6633 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 GSE190316,GSE190324_1_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-2052 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PPP2R5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13519 Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVTOKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88123 RAD23B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77434 Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48348 KE39 CCLE Cell Line Gene CNV Profiles 1.0 1.49574 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.833615 hematopoietic stem cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 RASGRP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0951 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSTK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57886 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.983434 Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carbamoyl-phosphate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.885 Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.1379 UBE2V2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34589 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -2.08523 Angelman Syndrome DisGeNET Gene-Disease Associations 1.0 null IRF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30023 acquired immunodeficiency syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.705144 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.86744 HCC1954 CCLE Cell Line Gene CNV Profiles 1.0 1.97019 proteasome-activating nucleotidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.7 REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCDC93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72687 cellular response to hydroxyurea GO Biological Process Annotations 2023 1.0 null Molting gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.055 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHUEM7 DepMap CRISPR Gene Dependency 1.0 3.84612 GSE211177,GSE211178_0_v_1_ets1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53847 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.57643 GSE186065_0_v_1_sirt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 MERO48A DepMap CRISPR Gene Dependency 1.0 4.8181 Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 2.00611 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.379 CXCL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12063 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9952 ARF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72964 GSE166004_5_v_0_pld1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95837 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Storage vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.969 Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8939 proteasome core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.280349 HNF4A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3557 cdx2_20696899_caco2_lof_human_gpl570_gse22572 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.24178 NMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54015 GSE201042_2_v_3_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bone marrow cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.256 UBLC1 CCLE Cell Line Gene Expression Profiles -1.0 -1.77355 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.247 SW1088 COSMIC Cell Line Gene Mutation Profiles 1.0 null PYGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20974 MFAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01212 MAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62474 Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2245 PSN1 CCLE Cell Line Gene Expression Profiles -1.0 -1.97999 PL18 COSMIC Cell Line Gene CNV Profiles -1.0 -3.40381 REST_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null megakaryocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22614 hsa-miR-4509 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.989674 ADRM1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3922-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3333 cullin-ring ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499042 Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17238 REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100551_PCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03205 SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -1.69906 OR2B6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85325 Perturb_1420_OE_Aatf_SRP257744 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.19406 GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Dlx5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.2313 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-2054 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 DANG CCLE Cell Line Gene Expression Profiles -1.0 -2.02621 Kinetoplastid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.905 NCI-H838 COSMIC Cell Line Gene Mutation Profiles 1.0 null ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38425 Spinal cord TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 NZOV9 DepMap CRISPR Gene Dependency 1.0 2.32834 GSE94849_7_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null GNA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69803 Endoplasmic reticulum lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.469 COLO684 CCLE Cell Line Gene Expression Profiles -1.0 -1.82148 Lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 TMEM18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17187 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.16564 Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08166 SUMO-targeted ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.241 Skin Cutaneous Melanoma_SKCM_TCGA-RP-A694-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null AUTS2-25519132-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5526 Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979861 Rectum adenocarcinoma_READ_TCGA-EI-6884-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.719092 MTPAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71141 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.891566 Other source TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 cellular response to nitrogen compound GO Biological Process Annotations 2023 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NGLY1-deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.286 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4797-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 GCIY COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4312 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.311 proteasomal protein catabolic process GO Biological Process Annotations 2025 1.0 null POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0016 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6418 SAMM50 Hub Proteins Protein-Protein Interactions 1.0 null RAB24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50917 PMC6568242__F2 PFOCR Pathway Figure Associations 2023 1.0 null Urinary bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 1.4438 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83755 FURIN_Deficiency_GDS3512_568_mouse_T-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4625 REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null REST_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Type 1 diabetes mellitus_Thymic epithelial cell_GSE11 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.38729 hsa-miR-432 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE105169,GSE105175_0_v_1_dhx36_human RummaGEO Gene Perturbation Signatures -1.0 null viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.406425 Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043757 heart TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 ITK_knockout_241_GSE12465 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.60161 SUIT2 DepMap CRISPR Gene Dependency 1.0 2.62817 Perturb_13142_KO_Ngly1_SRP166093 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.9684 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null l540 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07692 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14024 BFTC909 CCLE Cell Line Gene CNV Profiles -1.0 -1.63017 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 GSE158431_5_v_4_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null MON DepMap CRISPR Gene Dependency 1.0 2.00513 MYC_KD_GSE22139_685_human_medulloblastoma GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869311 HS944T CCLE Cell Line Gene CNV Profiles -1.0 -1.49277 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.365477 Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100581_TCx_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13009 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT115 CCLE Cell Line Gene Expression Profiles -1.0 -1.46674 Nerve ring TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.989 SW954 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9781 KLHL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86324 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914072 SUDHL6 CCLE Cell Line Gene Expression Profiles 1.0 1.96968 aspartic-type endopeptidase activity GO Molecular Function Annotations 2015 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26213 KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.50857 HCC366 CCLE Cell Line Gene CNV Profiles 1.0 1.62636 Charcot-Marie-Tooth disease type 2Y DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.038 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29791 Thymic cortical epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.749 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2519 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.09688 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SIRT4_KO_GDS4823_30_mouse_hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7045 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0545 Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2348 SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -1.67275 RVH421 CCLE Cell Line Gene CNV Profiles 1.0 2.42714 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24788 PMC12804025-mmc2.xlsx-LPS-Unnamed_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null heterotrimeric g-protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160053 DUSP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49197 REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-646 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1762 Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.928561 REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8628 anaphase-promoting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.458 ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null IRX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97114 hsa-miR-3972 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 1.80949 Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF114 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11493 hsa-miR-15a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040314 Nuclear proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.759 Proteasome core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.153 Thymus-nk cell Tabula Sapiens Gene-Cell Associations 1.0 0.250906 Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Childhood Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null hsa-miR-1270 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Thymic epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.813 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6396 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0274 GSE215351,GSE215794_1_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAPRE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.38456 LRRC8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35802 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07276 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 1.52236 PMC2423434__F5 PFOCR Pathway Figure Associations 2024 1.0 null 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28996 Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.37 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.672 CD40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70579 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Motor neuron disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.639476 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null endopeptidase activity GO Molecular Function Annotations 2015 1.0 null PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 CARD8 inflammasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.334356 496100623_PCx_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29288 hsa-miR-497 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 KINGS1 DepMap CRISPR Gene Dependency 1.0 4.71545 Aspartic peptidase domain InterPro Predicted Protein Domain Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11431 hsa-miR-544 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 SIRT4_KO_GSE56321_391_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-424 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.798 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null hsa-miR-4307 TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Angelman syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.285 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.9208 female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 PMC8814143-41419_2022_4530_MOESM12_ESM.xlsx-up_ZNF32_vs_Vector-Unnamed_1_ZNF32 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6336-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C14orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60747 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null HARA CCLE Cell Line Gene CNV Profiles -1.0 -2.11117 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20493 Multiple epiphyseal dysplasia 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.629 other source TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 culture condition:antigen-presenting cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 gut TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 OCT4-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.284 blood platelet TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 3.10125 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047141 ZSWIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57121 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.030262 Blood platelet TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47798 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.933116 CA-SKI COSMIC Cell Line Gene CNV Profiles 1.0 2.09073 Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FFAR4_KO_GDS4811_507_mouse_adipose GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARL6IP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53387 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84554 Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 CCLE Cell Line Gene Expression Profiles 1.0 1.42704 GSE89018_1_v_8_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Subcortical maternal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.885 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.0175 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-4649-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 JUP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68334 H3K9me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MACF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53115 SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.841534 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5351 Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.382 Retina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Rh-30 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.556 KCTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93172 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.5661 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.93831 NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SIRT4_KO_GDS4823_505_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64307 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.35 ZBTB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48334 Ring gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.589 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944609 Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.36779 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2887 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 1.36753 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84554 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VCP-NPL4-UFD1 AAA ATPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.671 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Marrow cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 5.0 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283