association dataset threshold value standardized value POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.3152 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3062 HSC-3 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.28027 HOXC9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1067 regulation of signaling GO Biological Process Annotations 2015 1.0 null SNU1327 DepMap CRISPR Gene Dependency 1.0 3.78138 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3656 thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.81983 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null negative regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2015 1.0 null Seminal vesicle fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.937 HD-11 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.801 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040273 chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.0784 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null 20460173-ImmPortAntimicrobials GeneSigDB Published Gene Signatures 1.0 null periodontium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.452198 Lewis lung carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.639 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13487 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6041 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 lipopolysaccharide GeneRIF Biological Term Annotations 1.0 null negative regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2023 1.0 null SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7917 defense response to fungus GO Biological Process Annotations 2023 1.0 null bp94 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.272 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.837361 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049255 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1777 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039667 KPNYN DepMap CRISPR Gene Dependency 1.0 4.54214 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040125 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063228 extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.7215 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3023 Prostate adenocarcinoma_PRAD_TCGA-HC-A76W-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.3941 HCC1954 DepMap CRISPR Gene Dependency 1.0 4.09563 PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS Rummagene Transcription Factor Associations 2026 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864557 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12012 loss GeneRIF Biological Term Annotations 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851128 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null HT1197 CCLE Cell Line Gene CNV Profiles -1.0 -1.51441 C4II DepMap CRISPR Gene Dependency 1.0 2.49716 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29367 EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9134 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2308 Acute diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.059 S100A9 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.466 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.14792 lymph node HPA Tissue Protein Expression Profiles -1.0 -1.42736 binding GO Molecular Function Annotations 2015 1.0 null negative regulation of MAPK cascade GO Biological Process Annotations 2023 1.0 null MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.652 POLR2A ENCODE Transcription Factor Targets 1.0 null FOXA1-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null gingiva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.548914 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5724 HOXC11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2553 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902827 COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31917 inner CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830954 HCC1954 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.828113 defense response to bacterium GO Biological Process Annotations 2023 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.873548 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.97417 KML1 DepMap CRISPR Gene Dependency 1.0 2.45186 response to external biotic stimulus GO Biological Process Annotations 2015 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.65926 response to stress GO Biological Process Annotations 2015 1.0 null LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929765 positive regulation of defense response GO Biological Process Annotations 2025 1.0 null Mesosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.092 regulation of multi-organism process GO Biological Process Annotations 2015 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056022 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5558 Antimicrobial peptides Reactome Pathways 2024 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.3496 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903776 Protein phosphatase 4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.575 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06421 EZH2 ENCODE Transcription Factor Targets 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053995 outer SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.92257 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45736 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.0142 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29459 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.913478 Splenic Diseases CTD Gene-Disease Associations 1.0 1.09576 defense response to fungus GO Biological Process Annotations 2025 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05188 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.20494 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059838 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1022 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5979 negative regulation of signaling GO Biological Process Annotations 2015 1.0 null EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3408 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039842 MEC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.45944 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38205 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0228 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null COLO741 CCLE Cell Line Gene CNV Profiles 1.0 1.67592 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908044 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25343 RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT55 DepMap CRISPR Gene Dependency 1.0 5.32239 EW-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null Vas deferens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.011 CNOT3-19339689-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null negative regulation of tumor necrosis factor production GO Biological Process Annotations 2023 1.0 null ICC3 DepMap CRISPR Gene Dependency 1.0 3.83715 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 Diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 M07E DepMap CRISPR Gene Dependency 1.0 2.41096 ERI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60162 NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 1.79816 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02761 Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ulcerative colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.543155 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1539 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of response to biotic stimulus GO Biological Process Annotations 2015 1.0 null GATA3_01_163 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63708 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.91933 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.743023 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2805 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null response to biotic stimulus GO Biological Process Annotations 2015 1.0 null LS1034 DepMap CRISPR Gene Dependency 1.0 10.2915 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Innate Immune System Reactome Pathways 2024 1.0 null PMC6689252__F6 PFOCR Pathway Figure Associations 2023 1.0 null negative regulation of response to biotic stimulus GO Biological Process Annotations 2025 1.0 null HOXD10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.72 IZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01742 PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08551 SKNFI DepMap CRISPR Gene Dependency 1.0 8.32752 antifungal innate immune response GO Biological Process Annotations 2025 1.0 null EM2 CCLE Cell Line Gene CNV Profiles 1.0 1.81682 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9303 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null defense response to Gram-positive bacterium GO Biological Process Annotations 2023 1.0 null subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03106 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85314 Follicular thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.899 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.1032 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07171 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.39117 defense response to Gram-negative bacterium GO Biological Process Annotations 2025 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.8667 SOX4 MotifMap Predicted Transcription Factor Targets 1.0 null lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30297 PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.38868 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053996 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844797 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.76963 RAJI DepMap CRISPR Gene Dependency 1.0 2.76646 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07189 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03915 regulation of cell communication GO Biological Process Annotations 2015 1.0 null lipid binding GO Molecular Function Annotations 2015 1.0 null regulation of MAP kinase activity GO Biological Process Annotations 2023 1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7278 Tracheal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 betadefensin GeneRIF Biological Term Annotations 1.0 null ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.543155 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07171 NCI-H1299 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14209 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0918 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -1.35756 tooth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.291008 Outer dental epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.528 IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37503 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63405 positive regulation of inflammatory response GO Biological Process Annotations 2023 1.0 null HT144 DepMap CRISPR Gene Dependency 1.0 2.9542 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.3236 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.937673 FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8004 JHUEM3 CCLE Cell Line Gene CNV Profiles 1.0 1.83668 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5489 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.305 UMRC7 DepMap CRISPR Gene Dependency 1.0 3.27413 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3751 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2594 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920085 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null Gingiva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.256 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0773 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.08771 CORL311 DepMap CRISPR Gene Dependency 1.0 2.01859 Periodontium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.294 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9547 cell chemotaxis GO Biological Process Annotations 2023 1.0 null HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.30409 NANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56682 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884328 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.6716 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00568 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10931 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.45888 negative regulation of tumor necrosis factor production GO Biological Process Annotations 2025 1.0 null NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.56861 response to other organism GO Biological Process Annotations 2015 1.0 null Peritubular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.749 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.3834 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9417 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053447 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.30604 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14467 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.99564 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9887 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.54975 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.130351 IALM CCLE Cell Line Gene CNV Profiles 1.0 1.33918 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0843 hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071288 NCIH2291 DepMap CRISPR Gene Dependency 1.0 2.09163 PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null RH41 CCLE Cell Line Gene CNV Profiles -1.0 -1.38953 yy2_20215434_hela_lof_human_gpl570_gds3788 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.07244 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6845 Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.46 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938654 positive regulation of response to external stimulus GO Biological Process Annotations 2023 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29459 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.7051 CUX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6453 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.25669 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12012 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Process Annotations 2025 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976534 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2043 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.852 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 HSC3 DepMap CRISPR Gene Dependency 1.0 4.47795 BRCA1_DEPLETION_GDS3791_38_human_Hela GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7083 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22878 HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88347 Tooth resorption DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.227 extracellular region GO Cellular Component Annotations 2015 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.973016 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29823 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25772 Defensins Reactome Pathways 2014 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.914454 extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83586 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06136 SKMEL24 DepMap CRISPR Gene Dependency 1.0 2.58131 Beta defensins Reactome Pathways 2024 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -2.18908 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6181 IZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09678 MHHES1 DepMap CRISPR Gene Dependency 1.0 2.12314 Autoimmune disease of skin and connective tissue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.523 Dental follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.534 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1793 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.296 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903776 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1845 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15285 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.69718 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092713 coli GeneRIF Biological Term Annotations 1.0 null ll29 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.822 SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2992 HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -1.70821 negative regulation of response to biotic stimulus GO Biological Process Annotations 2015 1.0 null negative regulation of response to external stimulus GO Biological Process Annotations 2025 1.0 null GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44791 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092692 Oxoglutarate dehydrogenase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.337 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33236 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.36041 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null antimicrobial GeneRIF Biological Term Annotations 1.0 null PANC0327 CCLE Cell Line Gene CNV Profiles 1.0 1.62054 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.919277 ERG ChEA Transcription Factor Targets 1.0 null follicular thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.17891 BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1992 antifungal innate immune response GO Biological Process Annotations 2023 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null S100A8 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.471 NCIH661 CCLE Cell Line Gene CNV Profiles 1.0 1.44851 Cervical mucus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.726 Atopic dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8006 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2936 HOXD12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9939 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5193 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908044 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3173 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9395 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3931 TRIM28_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3209 Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.468 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -1.42736 Elementary body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.749 RMUGS DepMap CRISPR Gene Dependency 1.0 2.88438 regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7967 ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29891 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.80824 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.83942 SKNMM DepMap CRISPR Gene Dependency 1.0 2.18688 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07917 COLO205 CCLE Cell Line Gene CNV Profiles -1.0 -1.48246 MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K27me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -2.30285 icSARS CoV_30Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.82346 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 salpingo-oophoritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.613 Inclusion conjunctivitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 JUN ENCODE Transcription Factor Targets 1.0 null CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.831941 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-21211035-GBM-HUMAN-BRAIN-GLIOBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30931 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.30836 intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.281868 parafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29965 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4148 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14954 NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.593 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.94425 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 111.429 HTT ChEA Transcription Factor Targets 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039901 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052071 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066747 cell chemotaxis GO Biological Process Annotations 2025 1.0 null against GeneRIF Biological Term Annotations 1.0 null basomedial nucleus (accessory basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0566 CEBPA-26348894-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Epididymis disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.443 LHX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17775 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2122 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1299 molecular_function GO Molecular Function Annotations 2015 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98783 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7175 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0354 ascites TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350001 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.87358 TRIM28 ENCODE Transcription Factor Targets 1.0 null ChIP_CNOT3_19339689 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC6689252__F6 PFOCR Pathway Figure Associations 2024 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.533 UWB1289 DepMap CRISPR Gene Dependency 1.0 2.96992 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6214 Beta-defensin InterPro Predicted Protein Domain Annotations 1.0 null Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.644 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.42736 thyroid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.502292 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27417 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3421 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1633 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870252 regulation of biological process GO Biological Process Annotations 2015 1.0 null PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2 BRCA1_DEPLETION_GDS3791_502_human_Hela cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.69967 Stratum granulosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.536 aureus GeneRIF Biological Term Annotations 1.0 null ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.038 macrophage cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.444115 defense response to other organism GO Biological Process Annotations 2015 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.2689 PAT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.703 negative regulation of signal transduction GO Biological Process Annotations 2023 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052873 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.63376 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 HUT78 CCLE Cell Line Gene CNV Profiles 1.0 1.3832 defense response to bacterium GO Biological Process Annotations 2015 1.0 null negative regulation of cell communication GO Biological Process Annotations 2015 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.2315 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum HPA Tissue Protein Expression Profiles -1.0 -0.948371 inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.357446 response to external stimulus GO Biological Process Annotations 2015 1.0 null MYC ChEA Transcription Factor Targets 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0112 KURAMOCHI CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063587 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.675 FOXI1 JASPAR Predicted Transcription Factor Targets 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7383 abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072902 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19162 HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6401 sperm GeneRIF Biological Term Annotations 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.641469 CCR6 chemokine receptor binding GO Molecular Function Annotations 2023 1.0 null 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.34285 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.38549 HOXB9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4892 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64807 CASKI DepMap CRISPR Gene Dependency 1.0 4.27426 Defensins Reactome Pathways 2024 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null COLO792 CCLE Cell Line Gene CNV Profiles -1.0 -1.94348 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 102.45 MG63 DepMap CRISPR Gene Dependency 1.0 5.89611 Epitheliocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.15593 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33236 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22996 biological regulation GO Biological Process Annotations 2015 1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44739 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6159 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11918 TT CCLE Cell Line Gene CNV Profiles 1.0 2.24239 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44214 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.409 chemoattractant activity GO Molecular Function Annotations 2023 1.0 null negative regulation of protein serine/threonine kinase activity GO Biological Process Annotations 2025 1.0 null CCR chemokine receptor binding GO Molecular Function Annotations 2023 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37128 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94404 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.1329 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15391 NLRP6 inflammasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.869 Genital mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.604 serotonin-activated cation-selective channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.9665 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.291 SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.33208 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0581 NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.70622 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32168 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.953 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2316 defense response GO Biological Process Annotations 2015 1.0 null Dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979457 MG63 CCLE Cell Line Gene CNV Profiles 1.0 2.59999 IGR39 CCLE Cell Line Gene CNV Profiles -1.0 -1.44925 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8195 Vaginal epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.795 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.96293 negative regulation of signal transduction GO Biological Process Annotations 2015 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0724 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3685 PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989757 RK-13 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.313 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7926 negative regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06828 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3719 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851128 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963801 phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.111269 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1182 LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6874 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.99952 Gingival epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.979 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83586 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17006 A498 CCLE Cell Line Gene CNV Profiles -1.0 -1.50603 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.916896 HCC202 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.06664 SW1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8987 Hypertrophy CTD Gene-Disease Associations 1.0 1.28919 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27228 YY1_KD_GDS3788_488_human_HeLa GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null response to stimulus GO Biological Process Annotations 2015 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64309 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.40625 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059508 Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.10535 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.4327 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4249 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50771 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.757002 Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36292 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60486 ovary HPA Tissue Protein Expression Profiles -1.0 -0.739463 SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null Sebocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.759 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7507 SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -2.14237 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0093 SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860461 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22996 marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.101113 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.233 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.266069 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0217 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.75701 ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1457 HS578T DepMap CRISPR Gene Dependency 1.0 3.21455 positive regulation of inflammatory response GO Biological Process Annotations 2025 1.0 null chemoattractant activity GO Molecular Function Annotations 2025 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.762 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.5471 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.795 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35003 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6726 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.84365 regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2015 1.0 null GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0642 follicular thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.3044 NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.52068 neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.158908 MBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59395 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9146 lipopolysaccharide binding GO Molecular Function Annotations 2015 1.0 null A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.24984 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03471 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52962 Contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7432 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5615 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844051 19933690-TableS2 GeneSigDB Published Gene Signatures 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7419 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25473 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.989237 regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2023 1.0 null 496100426_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.50086 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.106517 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0963 Keratohyalin granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.544 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -2.45678 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7189 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9867 Beta defensins Reactome Pathways 2014 1.0 null blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057925 motility GeneRIF Biological Term Annotations 1.0 null Paneth cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.401 Root resorption DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.234 LACTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99515 macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.1358 Psoriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.585 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863566 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.3549 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867212 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12934 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 thyroid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.695763 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27367 Epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.56 Renal epithelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.302 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.904 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5009 Epididymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.432 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0874 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851128 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9987 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17481 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 epididymo-orchitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.26 MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24359 lpsmediated GeneRIF Biological Term Annotations 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29459 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null 127399 DepMap CRISPR Gene Dependency 1.0 2.12431 regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2025 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50161 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870638 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1945 YY2_01_19 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.00439 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6707 regulation of inflammatory response GO Biological Process Annotations 2023 1.0 null thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.180317 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEV_60Day_None_GSE53731 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.78914 protects GeneRIF Biological Term Annotations 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null defense response to Gram-negative bacterium GO Biological Process Annotations 2023 1.0 null HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4484 CNOT3 ChEA Transcription Factor Targets 1.0 null POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.693 defense response to bacterium GO Biological Process Annotations 2025 1.0 null HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8351 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22996 CCLFPEDS0008T DepMap CRISPR Gene Dependency 1.0 3.29844 Tracheal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 negative regulation of MAP kinase activity GO Biological Process Annotations 2025 1.0 null receptor ligand activity GO Molecular Function Annotations 2023 1.0 null SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08407 GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2374 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60854 epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.484376 HCC2814 CCLE Cell Line Gene CNV Profiles -1.0 -1.41986 Vulvitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 AR ChEA Transcription Factor Targets 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.44952 CAL33 DepMap CRISPR Gene Dependency 1.0 3.10988 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0705 Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 negative regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null positive regulation of response to external stimulus GO Biological Process Annotations 2025 1.0 null response to bacterium GO Biological Process Annotations 2015 1.0 null PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4071 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0076 regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.917764 COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.47051 CCR chemokine receptor binding GO Molecular Function Annotations 2025 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null POSTN_01_293 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.92444 hippocampus HPA Tissue Protein Expression Profiles -1.0 -0.739463 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0792 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55499 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5483 SOX2 ChEA Transcription Factor Targets 1.0 null HOXC12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6436 throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.170807 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1889 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.07556 Immune System Reactome Pathways 2024 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72595 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1836 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47914 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SHP77 DepMap CRISPR Gene Dependency 1.0 2.96245 Allergic contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.032 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8825 HRT-18 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5781 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62999 NB7 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35477 regulation of MAP kinase activity GO Biological Process Annotations 2025 1.0 null LEDGF_KD_GDS1580_249_human_293T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36981 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02761 endometrium HPA Tissue Protein Expression Profiles -1.0 -0.739463 IZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88173 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.958 MM485 DepMap CRISPR Gene Dependency 1.0 2.63619 IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15691 Psoriasis vulgaris_Skin tissue_GSE13355 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.35122 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866358 YY1_01_18 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.78306 regulation of inflammatory response GO Biological Process Annotations 2025 1.0 null RH28 DepMap CRISPR Gene Dependency 1.0 3.48635 LS513 DepMap CRISPR Gene Dependency 1.0 4.15179 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.939677 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9359 CEBPB ENCODE Transcription Factor Targets 1.0 null mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.127804 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06613 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7576 negative regulation of protein serine/threonine kinase activity GO Biological Process Annotations 2023 1.0 null SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17582 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.79228 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851128 negative regulation of signal transduction GO Biological Process Annotations 2025 1.0 null myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099903 HTT-18923047-STHdh-human ChEA Transcription Factor Binding Site Profiles 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079048 WRO cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.414 HOS CCLE Cell Line Gene CNV Profiles 1.0 1.59778 NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08562 multi-organism process GO Biological Process Annotations 2015 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.227 inflammation GeneRIF Biological Term Annotations 1.0 null TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0832 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.68243 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Puberty, Precocious CTD Gene-Disease Associations 1.0 1.09576 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91297 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null negative regulation of response to external stimulus GO Biological Process Annotations 2023 1.0 null HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.57 Immune System Reactome Pathways 2014 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75685 TUHR14TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.68869 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8401 monocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.186386 negative regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2025 1.0 null Innate Immune System Reactome Pathways 2014 1.0 null mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06933 thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.870639 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3117 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48607 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Process Annotations 2023 1.0 null Bulbourethral gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 OCILY18 DepMap CRISPR Gene Dependency 1.0 2.95784 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.1747 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7127 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3571 wro cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.61211 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062204 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.7954 496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.60397 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2339 Vesiculitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.169 647V CCLE Cell Line Gene CNV Profiles 1.0 1.32989 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854634 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8548 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.27314 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4697 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.6904 MRI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57565 defense response to Gram-positive bacterium GO Biological Process Annotations 2025 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8066 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.8992 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.52855 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.704 H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 Allergic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.043 receptor ligand activity GO Molecular Function Annotations 2025 1.0 null TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.39 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.82149 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.925253 L1236 DepMap CRISPR Gene Dependency 1.0 4.5658 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9229 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056906 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9299 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28491 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.41522 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.8288 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 AUTS2-25519132-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.826929 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3349 regulation of cellular process GO Biological Process Annotations 2015 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902959 raw-264.7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.526744 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2384 Intestinal juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.591 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03244 SUDHL8 CCLE Cell Line Gene CNV Profiles 1.0 1.49793 negative regulation of MAPK cascade GO Biological Process Annotations 2025 1.0 null endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.270108 NB1 DepMap CRISPR Gene Dependency 1.0 4.67645 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1606 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.943341 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5975 positive regulation of defense response GO Biological Process Annotations 2023 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62564 negative regulation of MAP kinase activity GO Biological Process Annotations 2023 1.0 null VCAP CCLE Cell Line Gene CNV Profiles 1.0 1.78546 regulation of tumor necrosis factor production GO Biological Process Annotations 2023 1.0 null KYSE150 CCLE Cell Line Gene CNV Profiles -1.0 -1.32358 Epididymitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.445 negative regulation of response to biotic stimulus GO Biological Process Annotations 2023 1.0 null regulation of tumor necrosis factor production GO Biological Process Annotations 2025 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18984 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00216 stratum pyramidale of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27578 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7308 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.4211 TCF4 ChEA Transcription Factor Targets 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057478 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0728 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3571 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7829 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35475 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20788 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88484 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851128 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4335 cellular_component GO Cellular Component Annotations 2015 1.0 null 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.55771 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80521 hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09362 monocytic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.394197 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4589 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875167 negative regulation of multi-organism process GO Biological Process Annotations 2015 1.0 null inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18057 CCR6 chemokine receptor binding GO Molecular Function Annotations 2025 1.0 null MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9592 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846542 albicans GeneRIF Biological Term Annotations 1.0 null outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43626 regulation of signal transduction GO Biological Process Annotations 2015 1.0 null 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1708 spleen HPA Tissue Protein Expression Profiles -1.0 -1.42736 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9986 U937 CCLE Cell Line Gene CNV Profiles 1.0 2.14787 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1429 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.18408 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.951971 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053612 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69353 biological_process GO Biological Process Annotations 2015 1.0 null