association	dataset	threshold value	standardized value
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.27973
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00823
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2258
RUNX2	ChEA Transcription Factor Targets	1.0	null
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12197
Parabrachial nucleus, medial division, medial medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22292
Beta defensins	Reactome Pathways 2014	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7658
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3442
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5875
r3 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26066
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29071
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9488
Nucleus of the solitary tract, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0286
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7492
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18378
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.9016
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17984
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37761
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39026
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61434
KP-1N	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8849
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8775
LS123	DepMap CRISPR Gene Dependency	1.0	6.19971
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2364
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	2.29552
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5215
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.022
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4212
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42787
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15513
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14666
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76882
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29062
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10082
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PCI30	DepMap CRISPR Gene Dependency	1.0	4.45085
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39795
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07936
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2441
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59238
HCC44	DepMap CRISPR Gene Dependency	1.0	4.49874
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18954
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4562
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2849
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06326
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874894
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31796
KON	DepMap CRISPR Gene Dependency	1.0	4.37411
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	3.0226
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72392
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2309
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94999
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67534
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00609
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43207
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18129
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61179
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20701
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58083
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6887
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.77697
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14092
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36436
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.991
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05736
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.609181
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.17536
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74501
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.051
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6993
Discoidal high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49666
HS766T	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9885
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.64675
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936209
ventral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00616
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.75694
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.34567
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04349
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857753
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
intermediate stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25746
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885339
response to other organism	GO Biological Process Annotations 2015	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67534
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36226
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08058
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0221
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7337
HCT15	DepMap CRISPR Gene Dependency	1.0	4.06223
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07313
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	9.67506
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5349
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.89649
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8626
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41044
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4945
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36491
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78063
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS940-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35232
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bacterial pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.244
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2009
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271	DepMap CRISPR Gene Dependency	1.0	3.55284
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01934
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59113
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9439
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2216
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4685
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44747
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2705
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51063
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.89649
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70555
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56012
UBB_KO_GDS3906_491_mouse_Testis - 7 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4664
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.211
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0707
Smoking status (ever vs never smokers)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92502
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7524
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967694
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5634
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16185
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7376
Smoking	DisGeNET Gene-Phenotype Associations	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8116
liminal part of alar r1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06568
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22292
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.29963
vagina	GTEx Tissue Gene Expression Profiles	-1.0	-0.89649
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07917
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07261
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7302
SKGI	DepMap CRISPR Gene Dependency	1.0	4.1059
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2232
AGS	DepMap CRISPR Gene Dependency	1.0	3.57367
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82011
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06459
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0343
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957272
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46913
SLR25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38496
CAL29	CCLE Cell Line Gene CNV Profiles	1.0	1.6009
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34631
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8665
NCIH1373	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4855
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895919
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.70779
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1438
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10871
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8768
GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70885
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
CALU-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887338
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20153
Perturb_10236_KD_Kat7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.54716
GSE226770_3_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2897
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2433
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85094
Innate Immune System	Reactome Pathways 2024	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09055
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
GLC82	CCLE Cell Line Gene CNV Profiles	1.0	1.531
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.37229
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.162
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967694
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44217
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16554
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defensins	Reactome Pathways 2024	1.0	null
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14819
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35003
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.48048
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64909
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85094
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2771
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39677
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4172
KOSC2	DepMap CRISPR Gene Dependency	1.0	4.44463
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19249
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2043
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1708
RBPJ	ChEA Transcription Factor Targets	1.0	null
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20701
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16247
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92003
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06631
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0627
lateral part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.926
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.781215
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47519
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38984
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03366
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.932
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41044
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07607
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24796
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.77585
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35383
lateral part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16361
thought	GeneRIF Biological Term Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8875
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03368
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2617
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08439
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20153
COLO824	DepMap CRISPR Gene Dependency	1.0	2.40578
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUSA	DepMap CRISPR Gene Dependency	1.0	2.51058
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6377
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02152
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE144838_7_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMBC2	CCLE Cell Line Gene CNV Profiles	1.0	2.48671
SK-LU-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.47874
SW1271	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12456
PCI15A	DepMap CRISPR Gene Dependency	1.0	2.35301
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7445
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14949
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28617
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.43901
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.86069
LCLC97TM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32441
BICR31	DepMap CRISPR Gene Dependency	1.0	3.5186
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82011
substantia nigra compacta, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70885
immune response	GO Biological Process Annotations 2015	1.0	null
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06067
GSU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32051
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73251
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12697
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56999
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08302
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.55771
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01041
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell surface	GO Cellular Component Annotations 2015	1.0	null
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10082
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31131
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06075
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.606
NCIH1184	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34449
C2BBE1	CCLE Cell Line Gene CNV Profiles	1.0	1.45449
response to bacterium	GO Biological Process Annotations 2015	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966135
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	114.8
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.31278
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2364
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.615
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68243
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.9157
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01381
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16011
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68962
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.65926
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6346
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09555
SKMES1	DepMap CRISPR Gene Dependency	1.0	2.14132
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1437	DepMap CRISPR Gene Dependency	1.0	6.21784
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4409
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77331
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.99952
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.656649
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44512
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02823
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.67927
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.48521
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
Smoking initiation (ever regular vs never regular)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
p1 part of the substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44428
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86719
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46913
Beta defensins	Reactome Pathways 2024	1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24796
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2982
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50009
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8863
Viral pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.48703
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5297
stomach	HPA Tissue Protein Expression Profiles	1.0	0.875631
LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07811
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Substantia nigra, compact part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20774
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16833
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36989
NCCMPNST2C1	DepMap CRISPR Gene Dependency	1.0	3.1189
Antimicrobial peptides	Reactome Pathways 2024	1.0	null
LK2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32718
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06075
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9034
POLR2A	ENCODE Transcription Factor Targets	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29983
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08067
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06196
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885339
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2609
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5077
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33674
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.757768
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4689
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4946
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
OSC20	DepMap CRISPR Gene Dependency	1.0	3.01313
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84579
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9499
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	2.02889
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885339
mantle zone of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50866
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6929
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9494
multi-organism process	GO Biological Process Annotations 2015	1.0	null
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6001
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74667
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80059
defense response to bacterium	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8639
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38648
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10481
DETROIT562	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75229
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.936
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4457
response to biotic stimulus	GO Biological Process Annotations 2015	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8294
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5418
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22159
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18246
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8998
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31131
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57576
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36041
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86612
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0825
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.36662
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5718
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-0.89649
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8107
MMAC	DepMap CRISPR Gene Dependency	1.0	2.02567
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16833
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1552
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7031
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9607
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01976
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26228
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
rhombomere 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.926
EZH2	ENCODE Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70555
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1458
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08771
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30217
response to external biotic stimulus	GO Biological Process Annotations 2015	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.909
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50086
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7545
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.672
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21093
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08302
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9737
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.03739
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37818
MYCN	ChEA Transcription Factor Targets	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6909
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43699
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.269
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4838
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30084
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4751
K562	DepMap CRISPR Gene Dependency	1.0	2.00791
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25381
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18498
HT144	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65272
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9175
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00116
SUP-B15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26277
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC15	CCLE Cell Line Gene CNV Profiles	1.0	1.53569
NCI-H1836	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1437
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1809
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37818
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998173
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5489
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3557
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9405
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61837
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82011
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-0.89649
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0973
Immune System	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20774
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08639
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09623
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.5068
Primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29387
CHD1	ENCODE Transcription Factor Targets	1.0	null
TWIST1_01_252	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61258
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15685
ICC8	DepMap CRISPR Gene Dependency	1.0	2.06557
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05722
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29022
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11935
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8675
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
JHOS-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46657
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0169
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10871
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2283
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33783
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38723
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44512
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22063
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16104
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60058
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43207
Defensins	Reactome Pathways 2014	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885339
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUM52PE	DepMap CRISPR Gene Dependency	1.0	4.79262
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34631
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.706407
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.06
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10613
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44926
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16058
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26107
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47533
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0881
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.69967
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51693
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7632
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08342
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06631
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BHY	CCLE Cell Line Gene CNV Profiles	1.0	1.86301
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7206
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45104
UOK101	DepMap CRISPR Gene Dependency	1.0	5.00909
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33618
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
mantle zone of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0169
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60492
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.0528
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Parabrachial nucleus, medial division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02601
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27283
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67101
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.3531
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56613
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5502
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.23
rhombomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19544
NCIH2228	CCLE Cell Line Gene CNV Profiles	1.0	1.68828
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.64037
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32907
display	GeneRIF Biological Term Annotations	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2061
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	0.943635
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2333
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49557
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02152
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.08356
Mastitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36711
KON	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4047
encoded	GeneRIF Biological Term Annotations	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9023
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7321
r5 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0169
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.6723
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7876
biological_process	GO Biological Process Annotations 2015	1.0	null
CAOV3	DepMap CRISPR Gene Dependency	1.0	10.8881
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
HCC38	DepMap CRISPR Gene Dependency	1.0	5.11478
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22063
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RB1_KD_GSE50532_641_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8928
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9455
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16391
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13487
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.18191
RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10348
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06459
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3978
NCI-H647	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6628
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30269
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06075
response to stress	GO Biological Process Annotations 2015	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9945
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06459
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04178
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67221
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58149
r1 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51268
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77711
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0265
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01917
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0901
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02441
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.31542
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61835
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52384
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1609
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1809
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.910646
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0667
JUN	ChEA Transcription Factor Targets	1.0	null
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	2.13023
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1675
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885339
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9809
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15153
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70765
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.666
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9304
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33086
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986871
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8057
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4538
immune system process	GO Biological Process Annotations 2015	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2671
JUND	ENCODE Transcription Factor Targets	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5855
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47928
cellular_component	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23195
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60397
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	2.41075
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966135
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25121
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0279
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2108
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.7614
mantle zone of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16649
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Innate Immune System	Reactome Pathways 2014	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985297
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17337
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0225
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5653
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7992
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44217
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.39454
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4439
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04669
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.634
SU8686	DepMap CRISPR Gene Dependency	1.0	2.32197
antimicrobial	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15778
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15709
mantle zone of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0632
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48717
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3887
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24149
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1455
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0519
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9225
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.9232
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3462
mantle zone of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92003
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38092
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.927602
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1999
Beta-defensin	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16391
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26626
UACC812	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55537
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4074
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5088
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.00448
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4767
PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
defense response to other organism	GO Biological Process Annotations 2015	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3885
superficial stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08806
ICC2	DepMap CRISPR Gene Dependency	1.0	3.12987
DnaB helicase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14666
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07811
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0223
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14595
sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.127392
SF767	DepMap CRISPR Gene Dependency	1.0	2.47667
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06813
GATA2_01_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60002
HEC1B	DepMap CRISPR Gene Dependency	1.0	3.13325
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09828
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59493
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.733404
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1428
Bursa of Fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869733
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5332
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.95784
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.25548
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40625
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3446
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	1.89032
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07677
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12456
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.25669
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61837
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pre-primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.93197
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3506
CMAH_KO_GDS4770_420_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5583
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5391
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10675
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8522
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32176
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Critical COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19851
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97767
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857753
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.864
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85508
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52384
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869733
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7035
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
defense response	GO Biological Process Annotations 2015	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Prostasome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885747
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.061
Prudent dietary pattern	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.56232
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7024
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06119
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67534
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.422
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0637
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0225
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6115
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49857
FUOV1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85745
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5091
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.14224
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5334
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17516
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5644
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7198
OAW-28	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80906
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887338
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957272
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3006
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11397
innate immune response	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6741
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4976
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
KDM5A	ENCODE Transcription Factor Targets	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885747
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7094
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04263