association	dataset	threshold value	standardized value
phenylalanine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
Lewis lung carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27553
Erythroleukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
C 108 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.59
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.58
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
Cyclin D1-CDK4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
Nuclear membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
SP2/0-AG14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.37
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
BeWo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.428
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34485
PNGase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
mn60	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
Macrolide transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.905
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
Malignant mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.321
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.994
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.008
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8163
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6516
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19017
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24332
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
me180	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05747
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0687
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
pm85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.664
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heterochromatin domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2743
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320334
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
psi2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11767
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.471
BALB/3T3-T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
Cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.52
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Histone mRNA stem-loop binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
PMC12271188-Table_3.XLSX-total-RELA_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Vitamin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
Plant candle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
Mixed malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
Osteosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.22814
Lovo-li cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tm90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
Central nervous system hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05223
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
HPK1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
Juvenile rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
Rhoptry membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
HCT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Localized scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6096
Lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
CL-34	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.604
Hepatoma HLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.704
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Pancytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
Dxr protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.119
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.75
Cockayne syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.329
4805_MAP2K7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.29688
Uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.083
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
Mononeme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
Vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
horsetail-astral microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28348
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.878
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8849
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.025
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.065
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MutS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.573
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0857
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
HEp-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
Sporocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Hodgkin's lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
Lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.271
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08186
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5529
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1333
Scleritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Origin recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
cho/dhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.152
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64073
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.748
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72936
PMC11711664-41598_2025_85366_MOESM6_ESM.xlsx-AA-METABOLIC_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Pellicular membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
GSE230646_0_v_2_rbpms_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
Alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.377
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
Soft tissue sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.469
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38076
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64363
Cytosolic large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.10597
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.929891
Ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12272
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
igr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
ds19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
ml3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
Calu-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
M-14-K cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Macrocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.242
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Chodhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.642
Cervical canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47916
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0285
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.923
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
DU-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
Upstream stimulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.17
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3249
Leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.275
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05079
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Colo-320 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.552
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15946
Pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
Respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.944
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45481
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.472
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.438
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.16
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
Plasmodium malariae malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Plasmodium vivax malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43304
Breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.907
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
tetrahydrofolate metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6268
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.32
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.679
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92324
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9593
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33431
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
pg4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
4954_MED31_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.07501
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.123
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43271
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.707
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46782
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.31146
Gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
Parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41017
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1408
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.266
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12759
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.13802
corl23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
Spermary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
LoVo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
NCI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKOV-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
mitochondrial matrix	GO Cellular Component Annotations 2025	1.0	null
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
Mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44391
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57356
Rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
Hemorrhagic cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22821
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Transcription preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
MDA-MB-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
Hand grip strength	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8166_SMG5_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.21665
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.835
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28469
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64516
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214635
Epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.321
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11337
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pleural mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13206
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
BTN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18717
Skin sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Centrum semiovale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spina bifida	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.01
Transcription factor TFIIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08223
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
Conjunctival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
1670_CLOCK_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.17204
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291173
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.884
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
FLK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
Toxic shock syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Endocardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5502
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.451
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
Carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.314
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
SAOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3834
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.401
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Venous blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8724
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8339
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85137
pyrroline-5-carboxylate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Herpes simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.828
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48638
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.736
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
thymidine metabolic process	GO Biological Process Annotations 2025	1.0	null
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67658
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2655
496100415_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05361
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24598
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31488
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.843
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
MV4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.751
Calu-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18326
Biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
1774_COPG1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.04046
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46302
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9051
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29953
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0187
SK-BR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.966
succinate-CoA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3875
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
Blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.314
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74512
Chaperonin ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6428
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.489
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.235
g2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
Phosphoribosylaminoimidazole carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73731
igr37	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1434
Large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
mRNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
Dihydrofolic acid	MW Enzyme Metabolite Associations	1.0	null
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87155
CHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.653
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
Abdominal aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
Bone cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.643
folic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.929
MRC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
Glycine encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
Unilateral retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10759
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.213
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36111
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1692
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07309
Cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.992
Placental site trophoblastic tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.887
hutu80	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HECTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84278
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02572
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64328
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.835077
Adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.253
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22324
Central nervous system lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42514
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
Exoerythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
Retinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
Myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
Cutaneous leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
NIH-3T3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.813
Autoimmune disease of cardiovascular system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.439
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
Lung adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
Ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.58
dxb11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.443
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
MCF-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
SW-480 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50188
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63216
Intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.31
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HCN-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
Cystoid macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.993
Mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
Proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3495
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14386
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.48
Stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.093
Pars planitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59942
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10388
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50811
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71718
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Stevens-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1888
BRISC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
Congenital hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
OE-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prepuce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29352
S-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
Tendon sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.997
Mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.183
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09668
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
OV-2008 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.261
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.429
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoproliferative syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
Vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Osteomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
Lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.597
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26189
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55869
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72375
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
EAhy 926 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8375
TANGO2-related metabolic encephalopathy and arrythmias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.212
Meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Column	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Erythrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.304
o1192	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
Intraconoid microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
Filariasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
Gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
Peripheral blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
Pleura	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
Colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07558
Xeroderma pigmentosum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
U2-OS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
PEO-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.55
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
Anencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.24
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSTO-211H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
Hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
Large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
water-soluble vitamin metabolic process	GO Biological Process Annotations 2025	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0421
v79,b7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.032
Replication inhibiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5969
Cellulosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Choriocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.738
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.177
NCI-H196 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
Lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Plasmodium falciparum malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.591
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95115
Cytosolic proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
Fibroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
serine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
B-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.705
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40652
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Aseptic meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277982
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56736
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Mitochondrial matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Renal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
PMC6433273-pone.0214296.s009.xlsx-Table_D-S4_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_24_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Thiopurine S-methyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
Pneumocystosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.224
LNCaP clone FGC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
NADP+	MW Enzyme Metabolite Associations	1.0	null
RNA polymerase II transcription repressor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16888
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aedesalbopictus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
XPC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
Panniculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
One carbon pool by folate	KEGG Pathways 2026	1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
SW-620 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5213
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7847
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
Osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
Sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
PMC7581770__F2	PFOCR Pathway Figure Associations 2024	1.0	null
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
Schistosomulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
Folate transport and metabolism	KEGG Pathways 2026	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
Colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
PMC7519331-pnas.1921408117.sd11.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
pre-primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214832
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49057
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3234
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Progressive multifocal leukoencephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
NCI/ADR-RES cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Peptic ulcer disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24565
Mitochondrial outer membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.508
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09696
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.172
Chloroplast outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
Synovium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
T-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40275
Plasmodium ovale malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.598
Lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.233
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46088
Pleural mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
Childhood acute lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.885
MDCK-MDR1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.965
DnaB helicase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2027
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1139
Ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-DLX3_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
PMC7519331-pnas.1921408117.sd18.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09091
Orbit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.518
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
Organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.281
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19267
dicarboxylic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Holoprosencephaly 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
KB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.927
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0803
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5353
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.539
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSAT deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
PMC12417969-BRB3-15-e70857-s001.pdf-55-NFAT5_NFAT5	Rummagene Transcription Factor Associations 2026	1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12243
Delta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
Gestational choriocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Glucosephosphate dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
Breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.189
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
Congenital toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
Bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.557
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_downregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.283
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_increase_in_MLL-AF4_ChIP-seq_signal_371_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3889
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Serine deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
Isocitrate dehydrogenase complex (NAD+)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
Trans sulfuration one carbon metabolism and related pathways	WikiPathways Pathways 2024	1.0	null
Ulcerative stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
PMC11821528-41588_2024_2050_MOESM12_ESM.xlsx-MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung non-squamous non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.04
Primary cutaneous T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Cryptosporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
Mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
Outer mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9508
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
WiDr cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bronchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.726
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.43
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2979
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
Burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
Plastid outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04241
Colon-26 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
JEG-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Filarial elephantiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nso	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05985
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
Anterior uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
Scleral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Panuveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
FACT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
p3u1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.436
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0419
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cloned cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
T-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0971
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12486367-Supplementary_Data2.pdf-229-ZNF254_ZNF254	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Intraocular lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
5762_NPAT_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06568
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32444
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
Mantle cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82375
Conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47283
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10934
Persistent fetal circulation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06661
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.848
Abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.91
Sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8504
3t6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.334
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
Holoprosencephaly 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.124
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23359
Epithelioid trophoblastic tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Sympathetic ophthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6667
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69366
UFD1-NPL4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
Aphthous stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.115
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.143
P12-ICHIKAWA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.151
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.192
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04921
NS-0 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
Acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
CHO-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
Sec61 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35189
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.994
Metabolism of vitamins and cofactors	Reactome Pathways 2024	1.0	null
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07997
Colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
B-lymphoblastic leukemia/lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
RFL-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
Lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.988
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatosplenic T-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04149
Chorioretinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54993
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07674
BC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
Lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.709
T-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28225
Rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
Trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
Meiotic nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
Mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.18
K-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72236
Eye lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
MCM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
HCT-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.29
Myelomeningocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
Osteosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66711
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09379
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
SK-BR-3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.285
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65567
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41824
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
mpp89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
Homocystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
PMC12486367-Supplementary_Data2.pdf-426-FOXL1_FOXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Malignant pleural mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55312
Rb-E2F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4372
Gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
dystonia, DOPA-responsive	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70887
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC3930188-813067.f1.pdf-42-DEAF1_DEAF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.05
Sepiapterin reductase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73562
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.358
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
Marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.24819
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCRF-CEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.151
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
Internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.595
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.056
Acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.989
Mitotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27761
MiaPaCa-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0535
Biofilm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.372
T-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18524
Nuclear matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20824
Colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
i-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62782
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15173
8661_TAF1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.28407
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4937
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
MutSbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
Mitochondrial tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
Nasopharyngeal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
Melc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20495
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6079
Cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.411
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.055
PMC2813300-pone.0008960.s011.xls-SOX2_targets_in_human_ESCs-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235387
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76917
Acetolactate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
Synovitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.237
Transcobalamin II deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39676
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
Bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.915
T-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
Cul3-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228285
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1313
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19428
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.309
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20093
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.574
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47585
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
Lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.05
Lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.529
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38116
Primary effusion lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96647
Metabolism of water-soluble vitamins and cofactors	Reactome Pathways 2024	1.0	null
Hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
Lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.185
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6897
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07079
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Erythroleukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39278
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63925
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.439
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.694
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.184
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
Commensal bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypopharyngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10311050-mmc2.pdf-46-LMX1B_LMX1B	Rummagene Transcription Factor Associations 2026	1.0	null
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.882
Bone sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01745
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27139
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58128
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Glutamate formiminotransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
Hs-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16892
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
EDA2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54459
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44092
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2987
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.5
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HUT-78 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Gastrointestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.269
Megaloblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.376
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06132
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.628
Bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.7
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.284
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.58236
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.234
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.459
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2771
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
Leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Bone cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.643
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.298
Ischemic bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.84371
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.389
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
NAD+	MW Enzyme Metabolite Associations	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40698
IHF-DNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLD-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.37273
Ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.513
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.79
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04598
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
B-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37829
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35075
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
Hemoglobinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.665
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_significantly_downregulated_739_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52813
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3062
ribonucleoside-diphosphate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.362
Gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.346
Organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.704
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5194
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22284
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28546
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252319
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.312
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Bullous pemphigoid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92939
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
dihydrofolate metabolic process	GO Biological Process Annotations 2025	1.0	null
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.433
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78937
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.235
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
tRNA methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.483
folic acid-containing compound biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
Diffuse large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.146
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.298
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82677
Pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.948
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03219
Splenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.543
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75325
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4306
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29023
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	GO Molecular Function Annotations 2025	1.0	null
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
Liposarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
Optic neuritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Phenylketonuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60716
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04808
Spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.208
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32119
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.048
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0224
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5419
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.654
P493-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.968
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7209
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.292
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10861
Cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.974
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Subpellicular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
Nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
Methemoglobinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
Carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.417
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Orthogonal array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10534007-Table_2.xlsx-S2_overlap_MSC_down_B_V-395_common_elements_in_VM-CUB1_MSC_down_and_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13253
Respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.72
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
p3x63ag8.653	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.942
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09214
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13342
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88178
Infratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.03
Combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227019
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
Acne	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
g8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9597
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9858
pg13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
colo320dm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.26
MOLT-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
Pleural cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26063
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99103
Phosphopyruvate hydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95858
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.178
ZNF84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03305
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
MDA-MB-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
Micronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.738
Herpes zoster	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
Type II protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
Large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pemphigoid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
Breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
Metabolism	Reactome Pathways 2024	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.656
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.573
Peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
interleukin-6 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
Ankylosing spondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
l5178ys	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11824
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87341
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.091
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.056
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42421
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.798
NB-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78692
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50442
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Mature B-cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
Mycosis fungoides	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
MT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
tetrahydrofolate biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.84755
k1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23453
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
Dermatomyositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19329
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8373
Arachnoiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
2hx2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	2.09738
Vitamin B12 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Cellulitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
SW-1417 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
Mitochondrial isocitrate dehydrogenase complex (NAD+)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
ADA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1708
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Myc-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2901
Mature T-cell and NK-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Visceral leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
Acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04646
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Pleural disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
MDST8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7261
Transcription factor TFIIK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
Outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.906
Bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.136
NAMALWA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
6R-Tetrahydrofolic acid	MW Enzyme Metabolite Associations	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24047
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44891
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCF-Ucc1 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.213
Egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53546
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.016
Pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43213
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5683
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22683
Synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
Mucositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.376
1198_CASC3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.38404
Epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.417
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Daphnid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Burkitt lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Childhood leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
Colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
Bacterial microcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
PMC8160578-JCB_202009147_TableS4.xlsx-MYBL2_targets-Genes_n_532_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.588
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.427
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.174
mRNA binding	GO Molecular Function Annotations 2025	1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02775
v79clones	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5641
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.853
Rhoptry neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.664
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
Psoriatic arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.968
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3656
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
Chickenpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0474
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
Ccrfsb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
pre-replicative complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
Choroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
TMEM97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90974
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Severe combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37868
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80246
Colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.065
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46362
NALM-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
Acute nonlymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
Nuclear lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294814
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.021
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
adenyl nucleotide binding	GO Molecular Function Annotations 2025	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
Anaplastic large cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
p3hr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
Endopeptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.086
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
U-87MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24981
SERPINB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54986
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.64
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.604
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78582
Synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.208
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08998
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5565
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6517
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07716
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.141
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.306
Mouselcells	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.49
HeLa-S3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248634_1_v_0_gnas_human	RummaGEO Gene Perturbation Signatures	1.0	null
Blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
Babesiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Posterior uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0458
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.442
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7713
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.074
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4443
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6363
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44201
Proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.081
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.611
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03085
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.236
Nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
folate reductase activity	GO Molecular Function Annotations 2025	1.0	null
Kc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.03
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71108
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19353
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
Penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
SUP-T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35762
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Intermediate uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
Cystoisosporiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
EMC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
TRPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6232
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
DRM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.30915
pa317	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
Aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0001
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
NADP binding	GO Molecular Function Annotations 2025	1.0	null
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.272
SMIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69904
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
Half bridge of spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71248
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
TIM23 mitochondrial import inner membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.749
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
Proteasome core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45868
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1807
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.055
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.292
Pityriasis rubra pilaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Nasopharyngitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
Transcription factor TFIIH holo complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49787
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63834
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.216
Tetrahydrobiopterin	MW Enzyme Metabolite Associations	1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
dihydrofolate reductase activity	GO Molecular Function Annotations 2025	1.0	null
Placenta cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38343
Fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.984
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
pre-B acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3409
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GroEL-GroES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
xp13pv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45414
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.811
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.231
Onchocerciasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55243
293n3s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
Urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.735
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3087
Cerebral malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
Folate biosynthesis	KEGG Pathways 2026	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAJI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.248
Chronic myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.231
TPBG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52922
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Urinary bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0132
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0278
Lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.631
External male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
RKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4549
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.85357
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sebaceous gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
M5076 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.11
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
Arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
CX-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56053
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95254
Embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95716
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Ectopic pregnancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
xp23pv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
Mitochondrial respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.4829
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08263
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8079
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
Chorionic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1781
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.51
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27308
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HeLa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.974
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.331
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98222
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47452
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5083
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.127
Nocardiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bacterial pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
MutSalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.331
pyridoxine-dependent epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Peripheral T-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
Medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
Cystadenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71898
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HL-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
Nuclear envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.742
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273518
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Burkitt lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
L-1210 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.572
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42001
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.056
Metabolism of folate and pterines	Reactome Pathways 2024	1.0	null
JAR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
Choriocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.508
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50157
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
Chagas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Cytostome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.39
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06849
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7661
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
mnng/hos	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
ACF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.518
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-397-SIX3_AS1_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
A-2780 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
ERMES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
Digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
Fibrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2761
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41828
Reticulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.756
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36378
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
Breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.062
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28543
Joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.87
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8329
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Folic acid	MW Enzyme Metabolite Associations	1.0	null
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07998
Kaposi's sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41699
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8142
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44672
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1017
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36642
Transitional cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
l2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
Choriocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20491
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17544
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37094
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.18
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7714
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
pyrimidine deoxyribonucleoside biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294976
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
Ehrlich ascites carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12232
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
Opportunistic bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
Osteonecrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2529
Trichuriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
thymidine biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.752
Inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5334
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.11952
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
P-388 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.707
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
Friend erythroleukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70836
Rhoptry lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
RPMI-8226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
Uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
Behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21093
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Acute erythroid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53316
Ornithine carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88683
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Merozoite dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18802
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
l5178yr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hereditary folate malabsorption	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97111
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07122
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.08863
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.083
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.883
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
Intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.973
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3228
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
Aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GSE107594_0_v_1_hmga2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cleavage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
Erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9964
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.501
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
folic acid-containing compound metabolic process	GO Biological Process Annotations 2025	1.0	null
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
Pernicious anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null