association	dataset	threshold value	standardized value
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9492
BRD-K67082570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31419
ATF3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.672575
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
18768393-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
RMG-I	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.59137
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23643
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21762
E2F4	ChEA Transcription Factor Targets	1.0	null
stability	GeneRIF Biological Term Annotations	1.0	null
BRD-K21982562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02705
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02627
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	2.12037
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A99687212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32589
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01891
TET1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74542
BRD-K99100679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59056
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.581385
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.274
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.31193
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43399
BACH1	ENCODE Transcription Factor Targets	1.0	null
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06536
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42191735_buparlisib_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03851
post-translational protein modification	GO Biological Process Annotations 2015	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602892
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37822
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PMC3008507__F5	PFOCR Pathway Figure Associations 2023	1.0	null
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-29-PM90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463332
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1281
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAF1	MSigDB Cancer Gene Co-expression Modules	1.0	null
HCC15_LUNG	CCLE Cell Line Proteomics	1.0	2.41444
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AF-42-MP86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223172
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05251
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2124
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.674315
intracellular part	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03054
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876027
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058229
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9334
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20016
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071356
ds19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
Fatty Liver	CTD Gene-Disease Associations	1.0	1.06552
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37966
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21935
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7169_RBM28_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.538805
BRD-K35469110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50438
RCM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5656
AE-39-DG66_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.556298
DC-49-EJ23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31884
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.57468
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04923
Neurodevelopmental disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SW780	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6685
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38478
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03982
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1091
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119391
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05903
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45015
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72017
Pulmonary emphysema	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE146982_3_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-40-KK84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.617105
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.29624
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36061
CRCGN016_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22068
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14008
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0092
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3902
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25189
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23465
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89122
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.135152
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44118
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.83439
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3819805__F11	PFOCR Pathway Figure Associations 2023	1.0	null
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.321685
BRD-K15943105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04078
BRD-K91624805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1017
12687021-Table2	GeneSigDB Published Gene Signatures	1.0	null
DB	CCLE Cell Line Gene CNV Profiles	1.0	1.46402
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31372
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4081
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97624
BRD-A94420133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04013
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15424
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15147
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24324
patient	GeneRIF Biological Term Annotations	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983549
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
BRD-K30382953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00815
1-Guanidinium-7-Aminoheptane	DrugBank Drug Targets	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46839
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0094
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594853
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7383_KO_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2133
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38875
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74103290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.231
CTPS2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9336
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109278
Perturb_18557_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.45632
Perturb_17241_KD_IRF1_SRP337933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36663
BRD-K27824953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79406
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959923
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5546
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16821
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066198
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.372366
STAT1	ENCODE Transcription Factor Targets	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271067
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46393
Glucose	CTD Gene-Chemical Interactions	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01737
HT-1197	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72048
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.949633
DSH1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.48738
BRD-K89767945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03562
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2577
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03243
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01838
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01763
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00555
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45214
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09698
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM12	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.47079
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02082
PMC2994781__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_2610_KD_PCF11_SRP212229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.39375
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938044
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
semimembranosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566428
polysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.324951
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01199
neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350372
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.37486
DF-57-BL63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312445
CDC42SE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517393
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05345
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24659
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097756
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.53632
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01343
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78588
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03837
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00424
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21544
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508666
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28109
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07771
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.541117
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.22658
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70105
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22045035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49908
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.70246
h9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516104
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838336
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32182
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081337
BRD-K02624294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76989
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19549
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63687
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15568
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF3	Pathway Commons Protein-Protein Interactions	1.0	null
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1863
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36786
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.65
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KC-17-YN77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209341
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69194
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.845805
TFAP2A	ChEA Transcription Factor Targets	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.988692
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
u266	HPA Cell Line Gene Expression Profiles	1.0	1.71081
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55497
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.975062
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967881
Plasmodium falciparum malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.648
SH3BP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00392829
Plasmodium vivax malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.283
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64093
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Post-translational protein modification	Reactome Pathways 2024	1.0	null
glucose homeostasis	GO Biological Process Annotations 2015	1.0	null
BRD-K61370861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22395
RPS6KA2	Pathway Commons Protein-Protein Interactions	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
PMC5372827__F6	PFOCR Pathway Figure Associations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1217
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88738
MYC	ENCODE Transcription Factor Targets	1.0	null
FADU	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.99233
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4110660__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2166
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
transferase activity, transferring alkyl or aryl (other than methyl) groups	GO Molecular Function Annotations 2015	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H226	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44169
Pneumocystosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908452
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677966
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
7463_RPL35_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.571699
PMC7731198__F4	PFOCR Pathway Figure Associations 2024	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64438
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17122222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08729
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933591
HC-83-TS50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207456
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56883
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	2.59236
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353159
ELK4	ENCODE Transcription Factor Targets	1.0	null
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36125
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31325
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
cell suspension culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543359
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HB-77-UY14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.460863
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.857739
ATM	Kinase Library Serine Threonine Kinome Atlas	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30924
JB-41-UN43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283716
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24755
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63182
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095023
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.362
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05347
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.82319
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PMC5573165__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29293
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850731
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.42147
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49628
FD-43-EF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211056
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.3725
BRD-K66831269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13809
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15326
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EE-85-SK26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286315
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02925
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40064
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77299
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28294
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01304
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81292
coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.652994
BB-40-KK84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28446
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33611
binding	GO Molecular Function Annotations 2015	1.0	null
CEBPB	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61338
Delta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03407
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00479
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38712
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03184
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0392
PMC5527460__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K05902089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21693
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13453
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18457
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ammonium ion metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04646
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11855
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synthase	GeneRIF Biological Term Annotations	1.0	null
BA-34-BQ43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253035
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83124
Perturb_3537_KD_HNRNPK_SRP355083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.77522
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256464
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19516614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4489
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67042
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936586
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27488
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.08695
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27222
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02505
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.05584
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046556
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
spermidine	GeneRIF Biological Term Annotations	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61787
BRD-K83143868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0371
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23462
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90103
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12071
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40532
Hypertrophy	CTD Gene-Disease Associations	1.0	1.27039
PRKAG1	MSigDB Cancer Gene Co-expression Modules	1.0	null
QB-42-ET79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312821
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07269
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824322
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826497
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65552
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31308
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amnion epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
CXCL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632371
MB-72-YK93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214867
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525955
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7101
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15407
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99331577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01343
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02837259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65244
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54573
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36704
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12781
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.871
PMC2994781__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924789
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.6132
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3391
BRD-K98513899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21011
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38115
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959805
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
bone marrow cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133504
EIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6153639__F1	PFOCR Pathway Figure Associations 2023	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2142
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.937033
HFL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Intracranial Hemorrhages	CTD Gene-Disease Associations	1.0	1.04088
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1363
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45732
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15909
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91528
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.75856
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46833
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39342
OVCAR-8/ADR cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.835155
KIF18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15214
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K71604365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02337
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12436
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
BRD-K17940097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11292
PMC9727756-media-2.pdf-18-SNAPC5_SNAPC5	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.843434
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48508
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43316
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33795
BRD-K24864035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34038
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50149
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07227
NCI-H322M	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.74026
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7574
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16021
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853007
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70412
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.56801
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02258
BRD-K26734305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36306
HA-57-XH23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.907014
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06831
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39566
BB-55-JH29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323905
iloprost-427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16297
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28073
RELA	ENCODE Transcription Factor Targets	1.0	null
Nephrolithiasis_Kidney_GSE10162	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.970766
method	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933175
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827445
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	1.48277
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74933734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53054
BRD-K73792260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65309
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03602
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25042
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.096755
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60237
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70431
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66155
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87812655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29305
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33248
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
VB-27-PZ25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304941
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.702
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01644
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0053
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445653
BRD-A63503250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89926
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21888
Gamma carboxylation, hypusine formation and arylsulfatase activation	Reactome Pathways 2014	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80332
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54747
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06538
Acidocalcisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09027
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.82677
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1421
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996058
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333636
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83793
Perturb_7384_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K71836501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72588
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPA3	Pathway Commons Protein-Protein Interactions	1.0	null
Metabolism of proteins	Reactome Pathways 2014	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.373
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71166
WC-59-RG09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34408
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31952722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03332
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406561
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061563
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54466
Perturb_2734_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.29102
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.024
MHC class Ib protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960327
regulation of homotypic cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
translation	GO Biological Process Annotations 2023	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02973
Perturb_9718_OE_Wt1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.58599
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880066
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880966
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11442
PMC8740689__F1	PFOCR Pathway Figure Associations 2024	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-52-LF37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337074
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15295
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7692_KD_UPF1_SRP240357	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.17145
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31312
BRD-K96076719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61101
strongly	GeneRIF Biological Term Annotations	1.0	null
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41456
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29104
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60189
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.878
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68957
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111147
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61741
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20196
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55778
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60003
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44223
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7842
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05102
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81349
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070962
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.8521
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40322
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20661
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856371
Muscle Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
protein maturation	GO Biological Process Annotations 2025	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Keratosis pilaris atrophicans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42905
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876467
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20057
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21986
Perturb_5700_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66587
MB-72-YK93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.432584
modification	GeneRIF Biological Term Annotations	1.0	null
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590839
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44631
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27645
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02381
BRD-K96416345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.445
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63251
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14073
BRD-K11893906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62962
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00411
NE-93-AH13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202072
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852557
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.666221
BRD-K44121468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33158
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A99344113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91097
FLI1	ChEA Transcription Factor Targets	1.0	null
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.541117
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COBLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00722518
GF-98-RS57_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286238
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852947
GD-59-QF63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289394
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06744
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.2318
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of t cell activation	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853284
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20757
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5941
further	GeneRIF Biological Term Annotations	1.0	null
Perturb_4714_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	2.35959
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P31-FUJ	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.94782
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16964
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05152
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICR18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67311
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31063
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of leukocyte activation	GO Biological Process Annotations 2015	1.0	null
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9019
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33219
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26208
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66214118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13914
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87748094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32171
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02994
PMC8349405__F3	PFOCR Pathway Figure Associations 2024	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.519253
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55939
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18208
deoxyhypusine biosynthetic process from spermidine	GO Biological Process Annotations 2015	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23542
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
BRD-K49530286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21977
IPC298	CCLE Cell Line Gene CNV Profiles	1.0	1.62026
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36967
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K77392050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96946
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17806
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.920596
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22721
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3726
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53005
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07366
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6442_KO_RHO_SRP134183	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.46293
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554371
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18124
Pica Disease	DisGeNET Gene-Disease Associations	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944848
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13879
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07445
GAIT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.44479
TRIM66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17275
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960327
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23557
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14308
Perturb_7389_KO_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26852477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04731
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42599
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82882
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63174
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982688
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.57674
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0304
Refractory Cancer	DisGeNET Gene-Phenotype Associations	1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7079
regions	GeneRIF Biological Term Annotations	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
BRD-K60287130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68507
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypusine synthesis from eIF5A-lysine	Reactome Pathways 2014	1.0	null
OB-71-IZ36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235805
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Perturb_13592_OE_Mir322/Mir503_SRP348669	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55141
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-24-QF06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212575
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0113
BRD-K37961770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20481
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215234
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
PMC4408919__F3	PFOCR Pathway Figure Associations 2023	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.04017
SU8686_PANCREAS	CCLE Cell Line Proteomics	1.0	3.13096
H3K36me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16451
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80128
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37394
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0324
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of t cell proliferation	GO Biological Process Annotations 2015	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-63-FZ67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261171
SIMA	GDSC Cell Line Gene Expression Profiles	1.0	1.7833
plasmodium falciparum malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23256
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29201
Perturb_7380_KO_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.98578
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K87146261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21726
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52479
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864683
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239495
PMC6089552-oncotarget-09-31018-s004.xlsx-compound_targets_chip_rnaseq-Chip-seq_derived_EWS-FLI1_targets_Bilke_et_al_2013_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12705
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91841
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65915
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07784
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11861
Perturb_7009_KO_Lmna_SRP217125	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01214
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21688
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3035
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.04249
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10897
Perturb_3947_KD_RNF6_SRP126561	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.03848
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04671
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34581
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04258
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92209
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02037
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1508
sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066923
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4801
ONS-76	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.71904
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
systemic mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253479
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BD-62-ZF67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261566
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935918
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32048
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56746
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856763
ZNF143	ENCODE Transcription Factor Targets	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73262
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27992
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17242_KD_IRF1_SRP337933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.71186
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25147
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30543
Lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38737
AD-92-QZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30586
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03309398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27902
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16604
CCK81_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.64071
BRD-K15322427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05745
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865938
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17133
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-57-XH23_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3387
BRD-K05374764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34142
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.1659
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842563
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065552
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7390_KO|KD_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.138
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-54-NN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394419
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased hemoglobin content	IMPC Knockout Mouse Phenotypes	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.25619
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956165
BRD-K39809702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07576
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77743611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46919
BRD-K72098698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03533
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.74398
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.368985
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924789
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_5_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.191719
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Central Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.0561
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1448
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920533
AB-92-GP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36957
BRD-K21771537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14072
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.24482
DD-73-IP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358897
BE-50-RK99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388776
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42613
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76182
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54458
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633869
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30225
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGFR_drugactivation_30_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.2674
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2337
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2031
HB-77-UY14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446017
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01148617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39117
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974026
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
crystal	GeneRIF Biological Term Annotations	1.0	null
PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
polyamine catabolic process	GO Biological Process Annotations 2015	1.0	null
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.117853
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990808
single-organism process	GO Biological Process Annotations 2015	1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.983
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12357858-41467_2025_62862_MOESM3_ESM.xlsx-11_THP1-Proteins_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02036
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredPeptides-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00397
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1346_CCT2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.684437
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829112
Perturb_11013_KO_Plat_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78968
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53189
16484322-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
AD-32-RF17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229171
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30792491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87209
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49476
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23937
UBOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651827
Exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98133478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08334
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_7392_KO|KD_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K19830171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54182
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71588
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115884
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.848
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ChIP_TIP60_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34264
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JE-61-EQ70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352454
EB-66-IH06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200177
occipital cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06488
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05497
sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066206
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
capable	GeneRIF Biological Term Annotations	1.0	null
BRD-K53491881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32583
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1167
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.43678
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dohh	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85816
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypusineforming	GeneRIF Biological Term Annotations	1.0	null
Cerebral malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28961
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75713
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4081
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17093
BRD-K92022897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1448
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42757
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
PMC12079334-ADVS-12-2501734-s002.pdf-188-ENSG00000188868_ZNF563	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01921
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91
sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60255752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4672
BRD-K43484052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33048
roles	GeneRIF Biological Term Annotations	1.0	null
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.673532
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prenatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.50886
KB-72-ID36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318542
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5549
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85787
BRD-K74129999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94356
AE-04-DX45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03464
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11404
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glioblastoma	GeneRIF Biological Term Annotations	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39709
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066696
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06582
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40358
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83327
8196_SMYD4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.518183
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070738
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069678
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.47348
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARIH1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2929
cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243879
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16537
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
BRD-K90127029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09701
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.71285
PMC9886955-41420_2023_1325_MOESM12_ESM.xlsx-H6_14AvsH6_NC-Unnamed_2_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.896297
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910974
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX6B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52219
SNU1076	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46109
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28626
CCNT2	ENCODE Transcription Factor Targets	1.0	null
BRD-K73126584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48596
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879856
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
COR-L279	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14267
PMC4905481-oncotarget-07-11397-s003.xlsx-CtBP2_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.74509
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21544
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53431
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MM-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1234
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394893
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SA-63-NG30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299679
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943302
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.585
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HB-75-KT12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350338
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
because	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44024
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82624
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.94167
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15786
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug Usage	DisGeNET Gene-Phenotype Associations	1.0	null
DF-75-JD89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327235
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29251
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29002
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458514
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059108
PMC3817717__F2	PFOCR Pathway Figure Associations 2024	1.0	null
erythroleukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478534
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32749
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34055
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
BRD-K88282877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54281
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.41987
Hypertension_Adrenal gland_GSE1674	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.06534
tissue culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
LU-135	GDSC Cell Line Gene Expression Profiles	1.0	2.73875
8185_SMNDC1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.580573
pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.49262
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89223
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14176
abnormal preimplantation embryo development	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
polarity	GeneRIF Biological Term Annotations	1.0	null
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21474
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43073
Perturb_2874_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21393
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.45802
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.276
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86802
BRD-K56488838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06349
Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
splenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.823916
BRD-K78697404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39838
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-10-PR06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390246
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.80951
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.575
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2929
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35344
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77115
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06385
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6290138__F2	PFOCR Pathway Figure Associations 2023	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_94_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.5569
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991206
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229568
CRCGN009_HEPG2_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11061
MYOG	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15302
kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.16633
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03377
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864034
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66657
BRD-K32759631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10152
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76309489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18714
TEK	Pathway Commons Protein-Protein Interactions	1.0	null
Male cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23324
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K44244207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31412
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57793
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9497
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.826397
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37819
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33475
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47153
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL5491 (RAD23B)	NURSA Protein Complexes	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.40596
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10785
7524_RPS3_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512122
F36P	CCLE Cell Line Gene CNV Profiles	1.0	1.63645
BRD-K95485901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12227
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
configuration	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16821
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11603
skmel31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03998
BRD-K85572169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64246
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15401
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18395
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05943
Abnormal Muscle Tone	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03313
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03182
Electroencephalogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254891
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2337
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53103
BRD-K76734722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21578
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03321
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.201
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19393
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45688
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18228
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39566
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17759
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3047	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0712
BRD-K21729626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43326
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82125
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01162126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04352
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064333
positive regulation of leukocyte proliferation	GO Biological Process Annotations 2015	1.0	null
Ebola hemorrhagic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18733
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18749
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15449
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04047
BRD-K67344728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06185
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXP3	ChEA Transcription Factor Targets	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35438
PAX5	ENCODE Transcription Factor Targets	1.0	null
Perturb_18555_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.74709
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00601
IB-78-AY41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207943
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_6_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3713
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61067
BRD-K01266518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6693
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amine catabolic process	GO Biological Process Annotations 2015	1.0	null
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28537
GSE171724_1_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579814
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10546030__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_11035_KO_Spock2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3096
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65255
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51811
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057461
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86182
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
Hypotensive episode_Renal Tissue_GSE2401	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.9522
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.47594
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16724
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0024
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08697
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07702
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626319
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMRC6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20841
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05632
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.03493
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12596
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.50629
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03966
protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
RCC-JW	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.91559
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75636
BRD-K76449854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16553
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
active	GeneRIF Biological Term Annotations	1.0	null
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
translation	GO Biological Process Annotations 2025	1.0	null
BRD-K23960050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38351
highly	GeneRIF Biological Term Annotations	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
Perturb_14040_KO_Mbd1/Mbd2/Mbd4/Mecp2_SRP337936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56222
TNFRSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659892
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062522
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Anoxia	CTD Gene-Disease Associations	1.0	1.04538
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51087
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60571
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410919
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.00784
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93260425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34622
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61733751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11093
HN-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4898
BRD-A34826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14624
TAL1	ENCODE Transcription Factor Targets	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
Perturb_6290_OE_ZNF165_SRP390251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96335
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938298
Visceral leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14703
VMRCLCD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59403
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114172
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29946
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28854
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6712
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	2.14973
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83685
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065905
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423312
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922475
mast cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239799
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16872
AAMP	Pathway Commons Protein-Protein Interactions	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3337
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084569
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16966
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03995743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77356
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_10985_KO_Fam210b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59125
DE-48-HZ49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397819
HA-29-PM90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.413644
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43726
AB-26-BE29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237043
SK-MEL-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
TBP	ChEA Transcription Factor Targets	1.0	null
BRD-A20731954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.558
ovary	HPA Tissue Gene Expression Profiles	1.0	0.882776
Delayed Ability To Walk	DisGeNET Gene-Phenotype Associations	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.973285
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.948462
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K74978191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78404
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.10963
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450122
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4942
AIP	MSigDB Cancer Gene Co-expression Modules	1.0	null
PPP2R5D	Pathway Commons Protein-Protein Interactions	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12175788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46327
BRD-K76400756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01415
BC-20-WA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228877
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14561
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63877
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25935
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041175
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0987
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.31746
PMC4460069__F1	PFOCR Pathway Figure Associations 2023	1.0	null
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47917
quercetin-283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20713
H3K36me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127378
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17135
BRD-K56942203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50165
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174302
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30798
drc	GeneRIF Biological Term Annotations	1.0	null
BRD-K27680690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61227
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05928
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5747363__F2	PFOCR Pathway Figure Associations 2024	1.0	null
MDA-MB-436	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.10541
BRD-K53900606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30215
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16163
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16306
BRD-K28455914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29207
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07583
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974981
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08258
BRD-K54317642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92079
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.66089
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20392
GSE203158_1_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00284
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2653
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4110660__F2	PFOCR Pathway Figure Associations 2024	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9032
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052582
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206412
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43224
Nephritis	CTD Gene-Disease Associations	1.0	1.06188
GB-16-NN30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245963
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4988520__F2	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCV JFH1_168Hour-Huh7_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40356
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04596
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075734
latex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2288
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35388
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068963
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93142
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00731
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59433
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02995
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45242
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03375
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44179
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
SW1710	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70238
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00595
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bidirectional	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.17357
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74373
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6939
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.61472
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21857
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29603
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18738
BRD-K19225848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22609
BRD-K79833963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22837
PMC2720607__F2	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANP32B	Pathway Commons Protein-Protein Interactions	1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20394
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957451
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70663
BRD-A43330902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25582
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245402
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40614
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0132
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.974995
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K36709933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.162
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11252405-41467_2024_50426_MOESM1_ESM.pdf-9-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.9731
mice	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.63574
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994804
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0625
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98007
homeostatic process	GO Biological Process Annotations 2015	1.0	null
8793_TCP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.51311
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33832
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15492
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55524
BRD-K67141726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32214
KAT2B	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114862
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641064
Perturb_11178_KD_Eef2_SRP218948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.61158
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841795
protein oligomerization	GO Biological Process Annotations 2015	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50925
enzyme	GeneRIF Biological Term Annotations	1.0	null
OE-31-YC41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481615
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08721
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13628
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084482
CHD7	ENCODE Transcription Factor Targets	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196473
HNF4A	ChEA Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-63-KC77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374074
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44138
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K13122423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56767
QB-42-ET79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31637
NCE-G55T2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18089
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965522
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941237
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42229
Perturb_2876_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5222_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.60069
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
plate	GeneRIF Biological Term Annotations	1.0	null
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887709
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05218
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923973
USF1	ENCODE Transcription Factor Targets	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
MDAMB415	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72045
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22823
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K32259584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51513
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10196
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07469
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62092
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proteasome-activating nucleotidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903561
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37191
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302464
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
hct-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439507
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10323
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.908308
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC1195384__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63894
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.64493
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.47915
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19781
BRD-K29784863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26899
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05608
BRD-K18262761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65241
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13001
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.702
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860798
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51767
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87155
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909377
hsa-miR-4527	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50956
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87111
Perturb_2232_KO_Rela_ERP122918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.61702
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45026
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7127
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35332
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046476
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17841
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-11-OJ38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258368
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01009
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96553
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08869
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09055
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950229
ARF6	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064476
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633186
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832956
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20460173-ImmPortCD40LandAnti-IgMvsControl	GeneSigDB Published Gene Signatures	1.0	null
BRD-K22437400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14925
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16517
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.81299
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07721
SW579	CCLE Cell Line Gene CNV Profiles	1.0	2.48756
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K36me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	3.0622
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20542
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063449
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66064
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23939
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18457
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24619
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67249
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.513605
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.37902
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948115
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.647523
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
positive regulation of homotypic cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054077
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22538
TBP	ENCODE Transcription Factor Targets	1.0	null
pancreas	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.09167
Neoplasms	CTD Gene-Disease Associations	1.0	1.37761
VE-59-SD17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232506
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894187
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20372
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56851
PMC2720607__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Polysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.804
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSF1R_druginhibition_195_GSE57686	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.11032
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33065
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976249
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32407
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15841
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865829
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88417
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80101
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40065
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AE-04-DX45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.750539
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16243
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081272
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.802328
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4563
BRD-K23405268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52024
BRD-K87878529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58109
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051971
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.01324
BRD-K86923998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66841
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886186
Malaria	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4165-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12297
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832055
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70824
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.5852
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068113
4950_MED27_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.01527
BRD-K53026281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0711
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854244
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02771
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9118
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79736
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01438
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.5807
18689800-TableS7	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	3.42125
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0549
JD-94-BC04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.52453
Fetal Death	CTD Gene-Disease Associations	1.0	1.01587
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32535
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2625
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868718
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92109
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055435
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01549
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL105_LUNG	CCLE Cell Line Proteomics	1.0	3.13669
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33895
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89688
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02032
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
SF172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.69365
HUG1N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.31654
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nih-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
BB-40-KK84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500699
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02816
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931147
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.435
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03232
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE87615_0_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859438
8816_TELO2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567071
superficial stratum of OCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06488
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98887
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06954
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02393180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34761
Perturb_6857_KD_CNOT7/CNOT8_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40538
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4123
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5273
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38362
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921865
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061956
CD-97-ZV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203209
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
dhps540	GeneRIF Biological Term Annotations	1.0	null
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.0551
mantle zone of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20836
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3702285-cddis2013211x6.pdf-63-SNAPC4_SNAPC4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82104
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05693
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23886
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.816486
occur	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGTHW1	CCLE Cell Line Gene Expression Profiles	1.0	1.4871
Perturb_8507_KO_Gata4_SRP277626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.24738
EC-82-LV30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231257
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10687
BRD-K86638309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11147
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363026
CerebellumPeduncles	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07475
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02396
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.655024
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4364
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.905
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40999
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382966
CRCGN017_MCF10A.TP53.M_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27947
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61448
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92986
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
Subpellicular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.608702
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.93437
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22547
Endocytic and cytoskeletal regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BL2255 (PRKRIR)	NURSA Protein Complexes	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	2.17697
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903051
cellular biogenic amine catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74468
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0813	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.41592
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61791241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30374
BRD-K30053194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63783
BRD-A64761364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72593
BRD-K43700313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17382
ARF6	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77534
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.41663
CAL-39	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66697
Eukaryotic translation initiation factor 4F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.941
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
positive regulation of cell activation	GO Biological Process Annotations 2015	1.0	null
BRD-K31204557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18995
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31346
ternary	GeneRIF Biological Term Annotations	1.0	null
Solid Neoplasm	DisGeNET Gene-Phenotype Associations	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20035
HCC827	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55323
SPI1	ChEA Transcription Factor Targets	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04517
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33661
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10809
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51477
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06124
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HE-55-NT77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.548737
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36295
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51453
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98831
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46373
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.73372
CTCFL	ENCODE Transcription Factor Targets	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05745
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25665
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A13082766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34348
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49476
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19994
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18951
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14146
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267791
meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182666
REST	ENCODE Transcription Factor Targets	1.0	null
deoxyhypusine synthase activity	GO Molecular Function Annotations 2023	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.836017
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21272
BRD-K59069382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12946
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NAD	HMDB Metabolites of Enzymes	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05269
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54202
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54331
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71715
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977894
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834952
TF1	CCLE Cell Line Gene CNV Profiles	1.0	1.87773
Sunken Eyes	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K46655163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10048
macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
GSE198054,GSE198057_0_v_1_csf1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3122
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01743
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00916
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857322
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50757
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.380739
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.82368
ATN-1	GDSC Cell Line Gene Expression Profiles	1.0	1.47946
spiperone-1559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GD-59-QF63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396796
SNU478	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91257
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
deoxyhypusine synthase activity	GO Molecular Function Annotations 2015	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53677
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1155	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06743
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-68-DU31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291249
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
D-502MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44513
lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
RAVE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6826
deoxyhypusine	GeneRIF Biological Term Annotations	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10809
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83153
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29226
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13307
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.02262
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05493
Cyclin E2-CDK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274045
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916038
TCF12	ENCODE Transcription Factor Targets	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082615
Sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053928
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22173
BRD-K12826618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98852
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886647
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26823
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867897
GRANTA519	CCLE Cell Line Gene Expression Profiles	1.0	1.90921
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39566
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926551
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856371
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Eukaryotic translation initiation factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.321
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86084
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12515
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06779
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48762
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VE-59-SD17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381885
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95167
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23394
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48773
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23056
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933249
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0798
KMRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-2.99231
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pneumocystis Jiroveci Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28263
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06647
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6561_KO_Stxbp5l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44852
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826422
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70042405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5897
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39132
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10455
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.577064
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29994
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29367
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.916362
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0562
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22919
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079548
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52839
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1931
HNF4G	ENCODE Transcription Factor Targets	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5032 (CHD7)	NURSA Protein Complexes	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
assembly	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.624254
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633953
cytoplasmic mrna processing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.209513
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hyperlysinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
SK-MEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13099
H3K36me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915189
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.217
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104437
HA-57-XH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.686403
15897243-Table1	GeneSigDB Published Gene Signatures	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063512
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.14979
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-377-ZNF441_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.09625
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
eif5a	GeneRIF Biological Term Annotations	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9129
VB-27-PZ25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342408
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47945
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904611
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2428
butylated-hydroxytoluene	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9619
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
peptidyl-lysine modification to peptidyl-hypusine	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18365
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23361
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81524
upper dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07702
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eukaryotic translation initiation factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0367
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26719
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964488
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42376
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894994
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hiv Infections	DisGeNET Gene-Disease Associations	1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5265
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scleroderma_Fibroblast_GSE1724	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35753
BRD-K85456600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44643
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredProteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42814
mp90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.506
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10431
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.08716
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107067
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLR20	CCLE Cell Line Gene CNV Profiles	1.0	2.01274
fetal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323144
Infertility, Male	CTD Gene-Disease Associations	1.0	1.24056
AA-86-YV75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.723424
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60303
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866409
BRD-K07667635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13184
Perturb_7385_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78699
Oligospermia	CTD Gene-Disease Associations	1.0	1.65952
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83308
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45377
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48355
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K02337960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68661
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
genistein-382	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JB-82-MH86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220113
ANKMY2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15133
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BB-10-PR06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337773
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52209
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6194
hsa-miR-519b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.356709
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
orient	GeneRIF Biological Term Annotations	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994663
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77045
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.39007
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.24757
BRD-K73841784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0255
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933057
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12436
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861138
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10878
HNT34	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14898
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pre-Eclampsia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49476
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06703
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850425
ELF1	ENCODE Transcription Factor Targets	1.0	null
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.787
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039606
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.10063
Deoxyhypusine	HMDB Metabolites of Enzymes	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866364
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54279
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60483981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71714
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
BRD-K32362211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05064
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-63-KC77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406068
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17574_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66587
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98647
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91591
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20304
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76658
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43909206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5681
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09214
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933365
GABPA	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64908
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18275
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.50727
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93171
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903571
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09929
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.613522
translation	GO Biological Process Annotations 2015	1.0	null
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K90977883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45908
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K92891227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7086
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74082
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2254
BRD-K67556876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34099
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294561
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13058
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53462
organonitrogen compound catabolic process	GO Biological Process Annotations 2015	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862161
UD-20-ER54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272007
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18935
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.27316
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945412
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.15728
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303511
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82599
positive regulation of mononuclear cell proliferation	GO Biological Process Annotations 2015	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00771
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14767
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.41087
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18469
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.048
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polyamine metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K87939000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72543
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07349
BRD-K55311609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14925
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69125
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8833
inner CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92426
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.963496
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44995
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13251_KO_Dux_SRP098643	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41994
JB-41-UN43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232731
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1309
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12201
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K60780031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29037
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066333
FOS	ENCODE Transcription Factor Targets	1.0	null
Nimesulide_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00834112
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932902
lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079548
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23371
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
l-1210 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.738442
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78808
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46195
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K65005022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85051
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78118
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70724
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.3808
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30292
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16495
BRD-K40485332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95915
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585315
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45554
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14647
HMGN3	ENCODE Transcription Factor Targets	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1703	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40916
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40368
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409863
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.34141
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24267
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNSI9S	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2129
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.539
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100678
protein homotetramerization	GO Biological Process Annotations 2015	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64427
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06018
PMC5573165__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GA-79-ZF28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35545
BE-13	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0764
BRD-K76544773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18128
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850731
PMC3819805__F11	PFOCR Pathway Figure Associations 2024	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
16484322-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22051
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1169
BRD-K19965080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51822
regulation of cell activation	GO Biological Process Annotations 2015	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7598260__F7	PFOCR Pathway Figure Associations 2023	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44241
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996988
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850485
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41934
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASXL1	ChEA Transcription Factor Targets	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FC-05-ID99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219932
GSE71385_1_v_2_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21544
enrichment culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.653807
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48499
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09804
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59171
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06151
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899217
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50138
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1277
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989652
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35781
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215613
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.40902
Limb Hypertonia	DisGeNET Gene-Phenotype Associations	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263032
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87837
untranslated	GeneRIF Biological Term Annotations	1.0	null
PA-09-IB98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236715
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67390061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42479
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72386335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29867
NEC8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44108
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
sample	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33157
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.316456
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10679_KD|Mut_Cux1|Nras_SRP292900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.95307
perphenazine-1956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTSD - Post-traumatic stress disorder_Peripheral blood mononuclear cell_GSE860	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40305
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60841
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55007
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75762
endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315135
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827417
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60893
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
dhps437	GeneRIF Biological Term Annotations	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08864
NCIH1373	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83478
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K21356734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03275
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42651
Low Set Ears	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537344
UB-90-TA33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304797
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81862
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218212
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.73524
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947641
peptidyl-lysine modification to peptidyl-hypusine	GO Biological Process Annotations 2025	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0659
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43087
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
EZH2	ENCODE Transcription Factor Targets	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990417
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37399
positive regulation of lymphocyte proliferation	GO Biological Process Annotations 2015	1.0	null
DE-28-BW67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268572
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB-34-TO07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39176
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13833
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931178
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338474
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.00022
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67773
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Dom34-Hbs1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.973285
MFH-ino	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.43786
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5432-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480828
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.48802
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A97759891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38644
PMC11347378-41375_2024_2357_MOESM4_ESM.xlsx-Fig_7A_S8A_public_RNA-seq_DEGs-TFDP1_KO_HAP_cells_Human_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.28364
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345211
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1561
protein binding	GO Molecular Function Annotations 2015	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20549
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-19p13_overlap_Rifatbegovic2018-DCX-KD__CHR19p13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19712
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88502
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845326
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03375
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28955
FLI1	ENCODE Transcription Factor Targets	1.0	null
7827_SET_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.576768
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TEX45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01626
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stem nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42815
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14302
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906984
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997266
BRD-K76600600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02497
IHH-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.97375
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12468
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multidrug-resistant tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.535409
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14784
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93362
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.47853
23132-87	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.32098
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47691
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51575
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07729
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27792
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989398
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03341571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94169
ULK1_knockout_198_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.3134
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5218
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K53624506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16592
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38486
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12092
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54213
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92359570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8968
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11421
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01617
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tacrolimus-284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
Perturb_17442_OE|Mut_Tal1|Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.63511
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LTBR_INHIBITION - 35 Day_GDS2004_737_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56677
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34086
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71504
Spermidine	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.478
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
BRD-K14250524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15685
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2743
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466498
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58514
external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065063
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.531
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966497
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL29	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56415
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXC9	ChEA Transcription Factor Targets	1.0	null
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44261
Rovs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7071
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM192A_BREAST	CCLE Cell Line Proteomics	1.0	2.13592
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03766
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of t cell proliferation	GO Biological Process Annotations 2015	1.0	null
CD-12-NI84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241264
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07261
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
staurosporine-312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	2.30934
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07227
Ammonium transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119391
PMC4460069__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.01315
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10537
BB-73-ZW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250949
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18451
BRD-K72934808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46764
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07069
AB-84-PK04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307168
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
PMC1195384__F2	PFOCR Pathway Figure Associations 2023	1.0	null
should	GeneRIF Biological Term Annotations	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108253
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.152716
erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246124
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.974372
GSK3B_knockdown_206_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.55064
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510206
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
Deoxyhypusine synthase	InterPro Predicted Protein Domain Annotations	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314813
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16659
reveals	GeneRIF Biological Term Annotations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07227
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Complicated Malaria	DisGeNET Gene-Disease Associations	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857557
BRD-K56889360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.55736
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1357
imr-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396844
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26072
spermidine catabolic process	GO Biological Process Annotations 2015	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
DF-57-BL63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614168
BJAB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.08628
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
tretinoin-384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863154
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.68132
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAS1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.78858
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9855_KD_MSI2_SRP096137	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15418
SUM-190PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165573
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63232
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41014
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.028476
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18157
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76021
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36211
KPNSI9S	CCLE Cell Line Gene CNV Profiles	-1.0	-3.2102
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.80711
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.139081
UB-90-TA33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331771
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25466
indolent systemic mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.630027
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2023	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-2.38637
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.31508
OA-74-FH10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214416
DF-75-JD89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247216
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21108
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838544
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
movements	GeneRIF Biological Term Annotations	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5378_KO_Ago2_SRP178473	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31384
GSE199644_3_v_1_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.46198
Glutamate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
HDAC6	ENCODE Transcription Factor Targets	1.0	null
NCI-H82	GDSC Cell Line Gene Expression Profiles	1.0	1.62778
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838309
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32602
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4081
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.609711
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
mrc-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319863
BRD-K76389813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14731
BRD-K88758204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62514
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.391057
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377773
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20353
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993353
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-GENE_SYMBOL_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342112
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of t cell activation	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.933408
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08328
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6619
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218641
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03912
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DA-59-ZD74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236531
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01798
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876667
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77559
20460173-ImmPortAnti-IgMvsControl	GeneSigDB Published Gene Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81259
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.87542
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60952
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35712
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31292
tularemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.345675
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K59130783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00034
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32475622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69535
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.19877
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
8621_SYMPK_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.597123
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83287
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48670593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48998
BRD-K14216093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01266
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913046
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22919
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03256
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11580_KD_BUD23_ERP119404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.56
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04738
BRD-K77214724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55044
systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.78173
AE-28-LX10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.924744
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993205
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.52
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84501
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21719
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.968843
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN7_STOMACH	CCLE Cell Line Proteomics	1.0	5.9803
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210569
Ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.09
mutant	GeneRIF Biological Term Annotations	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BtuCD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.431
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09749
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07837
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45243
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	1.45227
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP4F3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629404
BRD-K99377541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00505
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872465
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.73933
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76482408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03418
JD-94-BC04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326013
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05977380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94212
Inflammation	CTD Gene-Disease Associations	1.0	1.39338
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837939
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11045
Perturb_7381_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.73207
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23868
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56715
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71641
PMC7266379__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11053
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359292
positive regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44299
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47004
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.849
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16976
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33218
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35546
BRD-K28785305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22896
AP1S2	ChEA Transcription Factor Targets	1.0	null
15284076-Table2	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Post-translational protein modification	Reactome Pathways 2014	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896097
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34793
VA-27-OT56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545489
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.976
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.946977
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398139
cellular biogenic amine metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1456
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475812
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.80673
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08579
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47198
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.17894
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65552
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230458
BRD-K53224741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97114
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967235
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879452
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.87116
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064672
BRD-K55815187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06264
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2609
BRD-K55779851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15277
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94238
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53721
PMC3930188-813067.f1.pdf-42-DEAF1_DEAF1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00551
Bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATN-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.16489
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49549
AKR1C4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557632
AD-32-RF17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201457
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.892107
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08293
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04833
positive regulation of cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14459
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7372_KD_UPF1_ERP012939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.77187
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17957
endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38505
forming	GeneRIF Biological Term Annotations	1.0	null
AA-81-CY65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217941
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941664
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-81-AG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204005
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP42-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2646
PMC3817717__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_13358_KD_Irf1_SRP234803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.32894
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893592
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51598
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14396
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00764
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20488
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823919
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236039
AB-17-WP43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397442
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914309
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04006
BRD-K66383189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5159
required	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78018
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04047
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OB-71-IZ36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319892
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868718
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44023
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938303
BRD-K83218047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27761
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16008
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68979
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.8928
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73539
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274101
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A19615705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19423
BRD-K69238239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14609
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67445
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37312
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887742
BRD-K94018786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69383
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32103
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.17214
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03715
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38454
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265995
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5460589__F2	PFOCR Pathway Figure Associations 2024	1.0	null
intermediate stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52808
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345051
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47298
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01417
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45583
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NB6	GDSC Cell Line Gene Expression Profiles	1.0	1.94324
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate homeostasis	GO Biological Process Annotations 2015	1.0	null
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2023	1.0	null
PMC4739739__F3	PFOCR Pathway Figure Associations 2023	1.0	null
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15073
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69736
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949412
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.995425
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2206
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52351
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.978067
BRD-K59317601_INK-128_HA1E_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26677
CA-96-UO48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231002
cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.161068
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954455
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534726
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0479
cellular	GeneRIF Biological Term Annotations	1.0	null
TD-69-UA90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229716
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839137
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
Perturb_3067_KO_Adig_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35594
cellular modified amino acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9521_UBE2V2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.535801
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072388
ISHIKAWAHERAKLIO02ER_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	10.7724
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75360899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08509
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11573
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053458
BRD-A68175400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.50911
BB-40-KK84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302793
CHD1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72255288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58071
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.889635
CHO-MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
GTF2B	ENCODE Transcription Factor Targets	1.0	null
CPEB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594147
PMC3008507__F5	PFOCR Pathway Figure Associations 2024	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53546
exodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34089
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64829
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40602
MTA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08092
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09568
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54272776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25021
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77282
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03611
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	3.27651
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90278
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10332
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57576
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47578
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35456
ZFX	ChEA Transcription Factor Targets	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60017729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03212
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.716501
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04052
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased hemoglobin content	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824013
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.05828
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96462
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33976
gene expression	GO Biological Process Annotations 2025	1.0	null
BRD-K71801719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02227
NUDT18	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K63960902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65519
cortical	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16826
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30323
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86605
ETS1	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	Pathway Commons Protein-Protein Interactions	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07702
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29106
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33283
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257609
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19395
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17357
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864387
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865354
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046332
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70788
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9261
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.982884
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07051
peptide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0565
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75673
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-05-MI00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297004
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27135
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36116
MS751	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82222
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4247
K562_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154542
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12981
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324472
Papillary Craniopharyngioma	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8705083__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRAF_knockdown_193_GSE5481	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.88216
exisulind-309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76980944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0669
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59797
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1369
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49696
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7682_KD_HNRNPK_SRP111756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.65962
positive regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
BRD-K87141723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62977
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
18427120-DataS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38213
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24795
SYNGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060888
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00284
YY1-21170310-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
11562467-Table3	GeneSigDB Published Gene Signatures	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8490503-thnov11p9519s3.xlsx-Proteins_High_MLL-Gene_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15243
TCCSUP_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	3.54644
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GUSPERIMUS TRIHYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	35.288
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214173
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88342
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17515
rna	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15056
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00717
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.18226
SAE1	Pathway Commons Protein-Protein Interactions	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.516127
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cutaneous mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202618
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rosiglitazone-369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17638893-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05033
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884633
Necrosis	CTD Gene-Disease Associations	1.0	1.66017
Diphthamide deficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
AF-83-BX08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227065
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914591
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_hic_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25280080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23783
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.681
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063449
Perturb_1298_KO_SOX15_SRP049465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9719
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	2.14377
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1363
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8843
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-0.923895
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42815
Hypotension	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36374
FRMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37724
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18372
RA-00-KI98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237925
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.575
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.439
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.14831
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
RB-55-KL42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298838
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.29337
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98896
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11846531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00133
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17717
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7371_KD_HNRNPC/UPF1_ERP012939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.13056
GC-28-YS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29056
BRD-K23075656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84782
BRD-K14394756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41303
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20707
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16524
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Perturb_3095_KO_Klf14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31632
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82754613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86603
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986914
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11657
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05693
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911227
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2023	1.0	null
Huntington's Disease_Blood_GSE1751	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.76785
GSE126402_4_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16511
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8509_KO_Bmal1_ERP009958	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23583
CRCGN008_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35595
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
BL5117 (ILK)	NURSA Protein Complexes	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00873
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67963
DPP8	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42096
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.716
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3434
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.565092
peduncular paraventricular area of PHyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03267
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43958
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1735
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69706
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43896
NFYB	ENCODE Transcription Factor Targets	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77419
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82125
PMC4394821__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23049
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594534
CAL-12T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51409
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2976
SW1783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19182
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531533
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35726223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23648
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31024887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23323
BRD-K75224334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23021
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00167
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924789
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
CRCGN015_MCF10A_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26049
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10372
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35923751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31707
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216976
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.767234
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12013
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
P12-ICHIKAWA	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8721
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29721
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.84217
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-20-EQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282365
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48826
18160667-TableS2	GeneSigDB Published Gene Signatures	1.0	null
UD-20-ER54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349518
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01497
SK-LMS-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.62041
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86461
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22447639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58014
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
rectum	HPA Tissue Protein Expression Profiles	1.0	0.973285
Venous blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
Perturb_4806_KO_Stat5b_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52639
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872463
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1071
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.352
CRCGN015_HEPG2_48H:H16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29748
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92361
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273342
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27732
GSE144453,GSE144454_1_v_0_tfdp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28268
ACHN	Achilles Cell Line Gene Essentiality Profiles	1.0	3.0994
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8397734__F4	PFOCR Pathway Figure Associations 2024	1.0	null
NR2F6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0039824
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54136
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32549
BRD-K44626845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70935
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89028
AA-91-SB25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201753
FL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08246
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2249
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05974
TE-15	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.65434
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1023
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53228
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.623429
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
Cystoisosporiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
SNUC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02112
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490978
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87544
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352918
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00176
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05002
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12901
T98G	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07356
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.994554
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spasticity, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10279
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223931
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03375
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09027
spectrin-associated cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913832
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.76185
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85362541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50135
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Schistosomulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Perturb_11544_KD_NPM1_SRP175176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.86395
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
K562_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018056
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26257
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09755
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.126
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838842
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05432
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951601
sgs cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54586
substantia nigra compacta, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1091
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90255725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69562
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2467
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0319
BRD-K75999096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29149
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08436
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897766
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223359
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401753
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16967
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A80010944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3844
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77272277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04095
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16362
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75098
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72439
versatile	GeneRIF Biological Term Annotations	1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36382
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31047
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963443
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850731
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Constipation	DisGeNET Gene-Phenotype Associations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37984
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25384
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.72792
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70315
EKVX	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.03005
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94437
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09136
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4323
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24665
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70098
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15379
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amine metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05971
sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PC-05-MI00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.469856
1351_CCT7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.52896
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.4898
GM133	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.934719
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VA-27-OT56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.709635
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02764
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073556
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76473
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86744
PMC7266379__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5170-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.641186
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38332
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03468
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11245
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54866
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cell population proliferation	GO Biological Process Annotations 2023	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63842
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K80779045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87355
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.927764
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.08416
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.71638
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07634
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905509
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.60295
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.023
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864566
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-56-WH26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.505153
8122_SLK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515234
bronchoalveolar lavage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712139
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14517
Congenital toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02049
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96315
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.42308
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.41478
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61257
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02936
ATF2	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60404
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00555
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2121
series	GeneRIF Biological Term Annotations	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVMANA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23174
DL-PPMP-1121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08281
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.41172
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04539
skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065294
PRKCG	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K18645499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19674
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25917968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57238
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.6965
E2F6	ENCODE Transcription Factor Targets	1.0	null
embryonic lethality between implantation and somite formation, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BE-65-HV88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333508
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.103
BRD-K42191735_buparlisib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dhps	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30884
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00457
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868207
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08131
GRANTA-519	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83329
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964569
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exoerythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30008
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2190_DHPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.701113
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03187
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944508
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26777
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.485
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66857
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41809
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.469
PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88362336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75214
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55874
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15633
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05257
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3995
structure	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2359
eye	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DB-73-BC12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323856
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73952959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62624
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.0467
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amoxapine-1931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1139
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903571
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12328371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79338
BRD-K42296822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57805
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37149
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959871
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08904
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65157
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53762
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540585
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070826
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84128738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05322
Perturb_10652_KD_Syncrip_SRP065017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.5689
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42537
regulation of leukocyte activation	GO Biological Process Annotations 2015	1.0	null
PECAPJ15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58771
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06609
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14963
Perturb_13423_KO|KD_Fbxo4|Hnrnpk_SRP359195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65452
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90292
AC-91-AV48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231449
SLR21	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19585
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860758
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75882
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03065
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.305143
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826685
IF-06-KQ42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216693
Mixed malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
Perturb_7382_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5953
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DND-41	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.92097
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211928
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10083
Perturb_7280_KO_CASC3_ERP118046	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1871
SYK_knockdown_279_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.42477
CTV-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.30822
CREB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K54053991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05345
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25169
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0371
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20807
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9126
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04653
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112094
BRD-K88369626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23274
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05347
BF-27-HP68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28775
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS-578-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K77718491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70465
callus culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.772344
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21458
Perturb_2250_KO_Piezo1_SRP355856	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.06738
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.55625
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01617
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	0.976762
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.69829
1321N1	CCLE Cell Line Gene Expression Profiles	1.0	2.04376
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946245
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.356686
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960138
hsa-miR-520c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.53547
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15264
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863178
pneumocystosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.22553
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35718
enzymes	GeneRIF Biological Term Annotations	1.0	null
ZNF367	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23818
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12337_KD_TFEB_SRP226507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.30772
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34119
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
12925741-Figure3	GeneSigDB Published Gene Signatures	1.0	null
HT29	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.38029
positive regulation of cell adhesion	GO Biological Process Annotations 2015	1.0	null
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49009
ELK1-19687146-Hela cells-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981869
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24805
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.2773
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51572
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20057
BRD-K90858591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79627
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.966
their	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00358
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17062
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78002
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04071
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47998
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541731
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16163
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062438
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73796
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161335
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53361
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97191
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11647
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71043
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50532
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77611
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36385
helper T-lymphocyte	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17176
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
AGS	GDSC Cell Line Gene Expression Profiles	-1.0	-3.0142
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.913503
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7391_KO_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NCI-H69	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.10905
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.29966
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13453
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4587
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35683
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090369
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5197
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5
tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080695
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6412
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850731
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18471
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0451
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51605
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35997
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07662
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48168
CTCF	ENCODE Transcription Factor Targets	1.0	null
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46261
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
protein tetramerization	GO Biological Process Annotations 2015	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96741
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98916
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25934
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HB-75-KT12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442794
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular modified amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.821921
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42891
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75655
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944603
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55064
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_294_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90483
Clinodactyly	DisGeNET Gene-Disease Associations	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.46837
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90111788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32081
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15294
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05148
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56851
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987219
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20077
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cobalt chloride-379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4689
PMC8836222__F10	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12712
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08595
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300262
RKO cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.828145
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60812
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920575
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885304
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201959
Abnormality Of Head Or Neck	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12643
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90497
duplex	GeneRIF Biological Term Annotations	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.04794
BRD-K55135464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49875
tf-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35334
BRD-K66896657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06876
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276027
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45415
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22541
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7	GDSC Cell Line Gene Expression Profiles	1.0	1.68668
Elongator holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ZFP42	ChEA Transcription Factor Targets	1.0	null
PIK3CA_knockdown_182_GSE46869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.46898
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898429
Perturb_2875_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90485414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22747
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.91479
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28041
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19835
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-10-PR06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207923
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856371
BRD-K61363662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68444
BRD-K52300725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19822
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.02485
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645814
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11066
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04719
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97468369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43741
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8063
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13079
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855283
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33685
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.72017
protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8302
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069917
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30144
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.495231
cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16604405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42091
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.091693
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14285
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20274
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03105
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36366
BB-55-JH29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.608887
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114493
regulation of leukocyte proliferation	GO Biological Process Annotations 2015	1.0	null
SUP-T1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.96996
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.911413
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72677
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0203
cytoplasmic stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.593072
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU878	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98092
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30932
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.20066
L-1210 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
BRD-K49992772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81261
Perturb_17440_Mut_Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19376
OB-71-IZ36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.515723
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860031
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27436
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Muscular Hypotonia Of The Trunk	DisGeNET Gene-Phenotype Associations	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918315
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00699
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0318
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27417
overexpressed	GeneRIF Biological Term Annotations	1.0	null
BRD-K61439686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01094
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	1.447
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02068
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
FD-59-TC81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23797
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2254
PMC8173714-NIHMS1678410-supplement-Supplementary_Table_2.xls-OfficialIPEXsig-Supplementary_Table_2_-_IPEX_signature_genes_with_their_average_IPEX_HD_fold_change_in_Tregs_and_Tconvs_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22313
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10354
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.831
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10428
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943713
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866853
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07458
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23969
NIF3L1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11799_KO_Fads1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.247
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967112
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.414946
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35479
wdr83	GeneRIF Biological Term Annotations	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1084
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10523
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10606
MXI1	ENCODE Transcription Factor Targets	1.0	null
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23801
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.291
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09113
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24777
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K43224838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52184
sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251015
ELK1-19687146-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82595
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.66621
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.843819
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29841
BRD-K06318195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67472
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833078
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0172
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918415
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	1.62703
CHD1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906452
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41606
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2449
ChIP_YY1_21170310	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32135
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.859511
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06916
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114232_10_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935245
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.37017
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07243
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WD-62-UB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215383
CC-07-DV77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326401
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31825
CCNH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00356084
spermidine metabolic process	GO Biological Process Annotations 2025	1.0	null
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083854
spbased	GeneRIF Biological Term Annotations	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-56-WH26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.826076
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
BRD-K30633507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22043
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
evaluated	GeneRIF Biological Term Annotations	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oligohydramnios	DisGeNET Gene-Phenotype Associations	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.50095
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NH-12	GDSC Cell Line Gene Expression Profiles	1.0	1.65489
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890519
VA-27-OT56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273756
primary cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282837
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69408624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77927
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825458
well	GeneRIF Biological Term Annotations	1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235141
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56926
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.26057
BRD-K84956158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13482
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDA1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12776
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60522
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31703
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37819
2fTGH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
CRCGN014_HEPG2_3H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06628
18794137-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K31874013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26931
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059654
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2H	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K42486632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31761
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06203116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31356
AC-45-EE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260068
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33334
BB-55-JH29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305716
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96219
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29452
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904059
tamoxifen-380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46478
PMC9237085-41467_2022_31238_MOESM4_ESM.xlsx-Table_4_MYC_BC_signature-HGNC_symbol_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84501
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949058
BRD-K69080049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38107
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904926
BRD-A17902629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5563
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41224
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17121
CRCGN016_MCF10A.WT.HP_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70555
E2F4-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC5460589__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-encode_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058946
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
SARS-BatSRBD_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40264
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18593951-TableS2	GeneSigDB Published Gene Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29401
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16143
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB436	CCLE Cell Line Gene Expression Profiles	1.0	1.66979
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62858
BRD-K38211037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46489
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-PROBE_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-06-AY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240189
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424199
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frond	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724041
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07835
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35537
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26353
Lung squamous cell carcinoma_LUSC_TCGA-85-8277-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19202
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055655
AKT1_activemutant_9_GDS2304	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.45382
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4591
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.835213
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49964
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Syndromic X-linked intellectual disability Snyder type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.259
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UB-90-TA33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331495
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31478
functions	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03015
PMC8384902-mmc2.xlsx-4_NEUROD1_high_subtype-Gene_Symbol_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69604
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09225
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10409
liver	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.24808
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5543043-data_sheet_2.xlsx-LPS_MDM_module-Upstream_Regulator_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.02783
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RCM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7059
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K91235484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35243
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12785
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85924
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325986
GP2D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08199
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55862
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30869
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36463
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14084
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06722
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946335
SLC7A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576622
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204617
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12515
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889456
PMC3435504-msb201237-s2.xls-Supp_Table_4a-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67288
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.03075
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995675
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89529
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53386
hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.46503
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5838
2925_FAM50A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.530613
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6153639__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K65207153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03912
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01535
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
KAT2A	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941563
BRD-K93942001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20682
Glycosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20906
human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.937874
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF1	Pathway Commons Protein-Protein Interactions	1.0	null
AF-06-AY37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.386494
PMC5706744__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K89333198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07919
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48155
egr1_20019881_retina_lof_mouse_gpl1261_gds3607	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.110384
EE-64-WM03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395102
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99835
apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.585942
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42103
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-73-GJ74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202814
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.32336
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49503
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.702
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929189
ELK1	ENCODE Transcription Factor Targets	1.0	null
polyamine metabolic process	GO Biological Process Annotations 2025	1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.724502
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07368164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73676
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20445
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39774
metabolic process	GO Biological Process Annotations 2015	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51116
19096012-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K73802986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.81613
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75275329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8188
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5747363__F2	PFOCR Pathway Figure Associations 2023	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.00376
LU-135	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.51521
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.47473
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831153
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98831
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DE-28-BW67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356106
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.292
PMC4394821__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26369
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
laticifer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393442
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983563
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03629
BRD-K94062017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53837
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00023
neurons	GeneRIF Biological Term Annotations	1.0	null
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36709
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36697652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11717
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05445
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18826
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2833
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254123
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852607
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K77483143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32381
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_107_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907152
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48057
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07672
TCCSUP	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.08926
BRD-K70426100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7191
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853378
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1957
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63837
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88258
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51037
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52727
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67626198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65687
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68219
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11048
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.802
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50641
BRD-K19534880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03931
BRD-K19712167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12146
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44042
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06706
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMIGD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545583
BRD-K65959331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04573
tick-borne relapsing fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
BRD-K65888165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38102
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37957
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52935
BRD-K78960724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43986
Hyperplasia	CTD Gene-Disease Associations	1.0	1.39646
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5644
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.97464
Plant gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074527
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9789
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83113
hsa-miR-186-5p	MiRTarBase microRNA Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05939
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5527460__F1	PFOCR Pathway Figure Associations 2023	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12669
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01112
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1429
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39632
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.029
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218563
BRD-K75637705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25346
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626677
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0362
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892584
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7111
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54416
NCI-H2009	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.69667
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20901
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K52582315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22982
BRD-K62833556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32081
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24397
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.09357
pirinixic acid-368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44481
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36643302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69584
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86256
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62552
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65738
ETS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541178
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19603900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05649
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.65479
BRD-K29298614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57931
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A68427178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5587
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924789
mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301758
malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.56311
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841349
Sacral Dimple	DisGeNET Gene-Phenotype Associations	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_11801_KO_Fam210b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.89415
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43315
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73256
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960327
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29724
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056425
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44968
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32597
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862143
BRD-K64066545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32096
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03339
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6154
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.51353
AA-86-YV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25029
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33317
Perturb_15390_KD_E2F1_SRP399677	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66383
BRD-K30467307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29698
BRD-K70945620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36657
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.54813
BRD-K24929039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43615
CRCGN009_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08249
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metaphloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171539
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35576
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peduncular subparaventricular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20923
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08692
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61938
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2856
DNAPK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40634
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16069
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92237
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30758
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00555
Perturb_7670_KD_HNRNPK_SRP111756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.52269
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887354
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29457
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95235
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41259
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21772
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
overlapping	GeneRIF Biological Term Annotations	1.0	null
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433757
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20738
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059334
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.426318
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28399
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
Active sex chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.029
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16681
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCI-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17815
Perturb_18554_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.71233
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13612
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16149
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31987
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.57022
oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38348
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01109
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3868
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47509
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52966
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07966
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76594
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873378
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08198
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8232
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.13924
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00401889
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45026
BRD-A03182941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18109
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90191
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987891
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
MYCN	ChEA Transcription Factor Targets	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59522787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28088
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92696
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067866
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600283
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3733
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2190_DHPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.619277
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103217
Neuroblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936728
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07188
PMC7825356-8844261.f3.docx-183-ZNF653_ZNF653	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77315
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
therapy	GeneRIF Biological Term Annotations	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC4739739__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055478
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75569
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067488
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04075
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3083
BRD-K07230804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47751
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.13848
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94243
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34628
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52613
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63472
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2733_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.17148
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.21651
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Calu-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49803
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43597
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993316
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25865
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15286
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37785
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97932
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8948
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34707
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86336
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.851
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06521
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04443
Prominent Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08595
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
BRD-K79678951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58634
BRD-K32577562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11734
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5706744__F1	PFOCR Pathway Figure Associations 2024	1.0	null
NFF	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.860129
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05432
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17065
Aerial root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-17-PN92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.619709
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
Cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.704
BRD-K12359218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20842
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23697
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143827
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
erythroleukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148583
PMC10864290-41598_2024_53494_MOESM1_ESM.xlsx-SRG_in_ClinVar-Gene_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45426
Hypothalamic lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15132
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	1.67093
CRCGN014_HEPG2_3H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07936
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25865
PMC4408919__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.42967
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7731198__F4	PFOCR Pathway Figure Associations 2023	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FD-35-PQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202012
BRD-K83109105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91925
BRD-K87990170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50516
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97623
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203361
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
axons	GeneRIF Biological Term Annotations	1.0	null
DHS-like NAD/FAD-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10505056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00568
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81667
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24775
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.879957
BRD-K67183010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1866
PMC10709143-41556_2023_1271_MOESM7_ESM.xls-PAX7_Re-injury-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-826-ENSG00000197044_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.1697
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12505
TE-12-BW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365043
EARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.396
PMC5372827__F6	PFOCR Pathway Figure Associations 2024	1.0	null
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35496
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.08904
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.12318
OELE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09033
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37227
BRD-K73039647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25166
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.66954
failure	GeneRIF Biological Term Annotations	1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.10536
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23317
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
KRAP_Deficiency_GDS3528_564_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BL7766 (MAPK3)	NURSA Protein Complexes	1.0	null
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36845
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gait, Unsteady	DisGeNET Gene-Phenotype Associations	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0712
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11307
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43258
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856371
Parkinson's disease 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Perturb_3291_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Actin cytoskeleton remodeling and signal transduction 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94243
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30363
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29965
CSNK2B	MSigDB Cancer Gene Co-expression Modules	1.0	null
Mammary-luminal epithelial cell of mammary gland	Tabula Sapiens Gene-Cell Associations	1.0	11.3219
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.816
BRD-K64317863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34559
testis_7f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.886278
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2673
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206893
VE-59-SD17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377884
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24044
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067838
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17465
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27381
Eukaryotic translation initiation factor 2B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164078
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-08-FF71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250553
KB-17-PN92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290225
BRD-K47951859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77815
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44299
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846165
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904461
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5065
SERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27804
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.66771
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Reactome Pathways 2024	1.0	null
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01129
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43029
IRF1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.716197
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.27595
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64565
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41344
Intercellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44547
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40341
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397222
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
KB-17-PN92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.997296
EIF5A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6894
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62118
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640081
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.28897
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69911
OV2008/C13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11319
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-ChIP_and_HES4_UP_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00218
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9741
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20888
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36315
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15677
Cytosolic large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53789
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88954
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2821
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058061
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114836
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2008
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061264
LCLC103H_LUNG	CCLE Cell Line Proteomics	1.0	2.97181
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
fludrocortisone-281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064306
bronchiolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.755342
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296318
TRIM28_knockout_303_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.6261
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARPC1B	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A953-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17482
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2814	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11536
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03259
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837376
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27073
MB-72-YK93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243328
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	2.2561
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4678
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13009
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30165
PMC7253612__F1	PFOCR Pathway Figure Associations 2023	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1846
GSE126402_4_v_0_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44299
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.31682
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01138
dhs	GeneRIF Biological Term Annotations	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1034
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21458
Movement Disorders	CTD Gene-Disease Associations	1.0	1.07732
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39566
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99059
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56488
hsa-miR-526a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6809
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966589
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374243
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94480039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.36801
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93172
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31226
BRD-K89637567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3427
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054942
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.9868
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07702
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12456
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18337
Perturb_4715_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38906
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12665
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27366
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33522
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.544411
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIRBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0042174
AF-06-AY37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.934186
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5929
SIRT6	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28779
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS255T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87508
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271713
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90701
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCIY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83304
BRD-K65108634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18456
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517518
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuroblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5926
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.985379
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ELK1	ChEA Transcription Factor Targets	1.0	null
HCC827GR5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07816
Infertility	CTD Gene-Disease Associations	1.0	1.19542
SURF2	Pathway Commons Protein-Protein Interactions	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16475
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13795
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09856
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03422
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microcephaly	CTD Gene-Disease Associations	1.0	1.08055
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.108795
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10718_KO_Hck_SRP340501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65847
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06838
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-56-WH26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482384
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00984
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01118
BRD-K57096799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00601
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44297
prior	GeneRIF Biological Term Annotations	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06737
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-518d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K49415484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27488
RIPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461407
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11545
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912326
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03293
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14051
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
surveillance	GeneRIF Biological Term Annotations	1.0	null
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158384
mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.141769
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mutual	GeneRIF Biological Term Annotations	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38787
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JB-82-MH86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300864
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10695
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
fm3a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05369
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5644
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	1.40655
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCL3L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560114
1,3-Diaminopropane	HMDB Metabolites of Enzymes	1.0	null
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37473
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67582
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062171
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	2.04315
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02548
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0117
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01777
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42557763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13383
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30269
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932423
PC-05-MI00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.93069
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K85775326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05537
spermidine metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863948
JB-82-MH86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.600361
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5282
eukaryotic translation initiation factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.319328
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53927
PMC6424098-mmc5.xlsx-CEBP_Binder-Gene_names_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897261
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923559
BRD-K80690345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32654
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.935137
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06386
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958656
spermidine metabolic process	GO Biological Process Annotations 2023	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.8835
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37780492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41772
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Micrognathism	CTD Gene-Disease Associations	1.0	1.08762
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HTC-C3	GDSC Cell Line Gene Expression Profiles	1.0	1.85463
PMC3435504-msb201237-s2.xls-Supp_Table_4c-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100549
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.021
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562605
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272918
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2015
BRD-A28153253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45769
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30302
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.92166
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34026
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.262
TPR	MSigDB Cancer Gene Co-expression Modules	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0032
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833448
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04875192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18332
SRP9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40634
OAW-28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47368
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19448
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48008
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.36088
Dysmorphic Facies	DisGeNET Gene-Phenotype Associations	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38065
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.41921
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55651
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2234
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.839
OE33	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44891
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059172
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
BE-50-RK99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36746
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42069
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24812
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064017
regulation of mononuclear cell proliferation	GO Biological Process Annotations 2015	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77436
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.324201
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.79
BRD-K50498614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21524
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.039
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40564
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14583
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655552
BC-52-NW28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295337
BRD-K37616496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15238
H1_Derived_Mesenchymal_Stem_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.44139
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-28-LX10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.611823
BRD-K05185748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27789
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10311
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090341
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.47876
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48396
BRD-K18562194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02754
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78516
Semimembranosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2683
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6437
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927424
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3798
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15117
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38626
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
TRIM28	ChEA Transcription Factor Targets	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.599854
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368441
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39193666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19543
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.009
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.300679
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.35299
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Jurkat	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.41644
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
CHD1	ChEA Transcription Factor Targets	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214091
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56787
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06098
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69429
12917485-Table9	GeneSigDB Published Gene Signatures	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
BRD-K74259627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99663
BRD-K99387963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23342
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.04348
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62709
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.54448
BRD-K45062933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59221
SIN3B	ChEA Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93277
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67099
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.931989
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4651
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00849
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gene expression	GO Biological Process Annotations 2023	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.980494
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-SL1	GDSC Cell Line Gene Expression Profiles	1.0	1.47106
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04629
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887154
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KALS1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.5176
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.018131
TK10	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0694
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.932669
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903571
PMC3348545-NIHMS263168-supplement-3.pdf-380-ZNF433_ZNF433	Rummagene Transcription Factor Associations 2026	1.0	null
1840_CPSF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.524011
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4152
primary culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123733
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65097
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31606
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53141
DC-63-KC77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361348
STAT3	ENCODE Transcription Factor Targets	1.0	null
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.948398
cobalt chloride-383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09932
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
BRD-K40088786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35626
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7335
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37496
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KURAMOCHI	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.4741
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866991
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15658
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824961
ACTR2	Pathway Commons Protein-Protein Interactions	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	0.984619
BRD-K66735533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7294
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Craniofacial Abnormalities	CTD Gene-Disease Associations	1.0	1.28303
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01625
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-175	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83375
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
lisuride-1962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HB-75-KT12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.753426
HA-83-HZ77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267578
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20238
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4586-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05965
r86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
BRD-K88135858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00044
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0766
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18243
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_213_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83708628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0866
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04551
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91346
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67702605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15921
BRD-K04819729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10608
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07712
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU840	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27366
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26415
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21588993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10535
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
UACC-257	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.22993
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.43267
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0265
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	2.92434
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78648
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24157
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49586
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.85448
BRD-K34414758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88826
SU-DHL-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.37176
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.95025
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921597
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
peptidyl-lysine modification	GO Biological Process Annotations 2015	1.0	null
regulation of cell adhesion	GO Biological Process Annotations 2015	1.0	null
BRD-K50367303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40875
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54285478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41857
independent	GeneRIF Biological Term Annotations	1.0	null
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10972
BRD-K51140037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1669
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880265
decreased cell proliferation	MGI Mouse Phenotype Associations 2023	1.0	null
YY1-21170310-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.787325
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.31225
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1577
LN340	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17107
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57061
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23218
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391176
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.39574
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25355
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39963
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.029
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878258
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66439
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-04-DX45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37409
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848436
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.752
Cytosolic small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60642
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.715524
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55063
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86025005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63146
RCOR1	ENCODE Transcription Factor Targets	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901348
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10598
Bronchiolitis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05849
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10864
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34319
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.158849
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14981
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47087
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11016
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.03604
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tylosin-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06034
FOSL2	ENCODE Transcription Factor Targets	1.0	null
SYK_knockdown_189_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.42395
valproic acid_homo sapiens_gpl4685_gse45587	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59458
HHV-8_72Hour_18587055_GSE6489	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.77879
hsa-miR-519c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K31460017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74978
BRD-K15775306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69931
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924789
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
deoxyhypusine synthase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38949
TIE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541595
BRD-K72833997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70403
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1974
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59324446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43281
E2F6_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90294313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33283
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88333
MCF7_ZM 447439_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123355
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063945
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975023
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994073
SRRM2	Hub Proteins Protein-Protein Interactions	1.0	null
SRRM2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183067
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475812
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39391
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42001
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91081
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78353
Perturb_7898_KD_NCL_SRP337780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.62625
lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376119
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41896
RELA	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39254
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298017
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874926
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314297
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.238
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39694
BRD-K33956247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0905
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07052
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6075
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904498
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.852284
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63864
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
10521349-Figure3	GeneSigDB Published Gene Signatures	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30078
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70724
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
JEG-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95803
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44578
AE-28-LX10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.715365
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21544
PMC7598260__F7	PFOCR Pathway Figure Associations 2024	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_7_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
20937356-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21509
Hypusine synthesis from eIF5A-lysine	Reactome Pathways 2024	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864459
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.61977
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32862
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
Reticulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315088
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497826
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15808
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-92-GP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217172
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01835
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74968522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18946
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
BRD-K82968130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08626
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23567
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867675
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09473
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2337
DiFi	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.98769
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235423
MYC	ChEA Transcription Factor Targets	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080424
9226_TRAF2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.884582
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05596
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17211
generating	GeneRIF Biological Term Annotations	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04547
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13092
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.60611
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48657
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08998
BRD-K09900382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68205
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61517
BRD-K72800151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21322
Keratosis follicularis spinulosa decalvans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26791
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.68365
Perturb_13989_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.3521
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40733
just	GeneRIF Biological Term Annotations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00348
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63517
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48837
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42815
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VA-27-OT56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433453
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81608755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13048
regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
BRD-K93101873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15259
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K77520720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18663
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19295
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08892
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5173
EBF1	ENCODE Transcription Factor Targets	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.8389
BRD-K23825243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10727
BRD-A99644411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00954
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0468
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.1597
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_proteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.048
6768_PRKDC_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.521799
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6923
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypusine biosynthesis	HumanCyc Pathways	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OA-51-KF88_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24705
BRD-K65257143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7247
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
Perturb_2882_KD_MAGOHB_SRP144009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.4662
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01558
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553931
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19267
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122958
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78186
NCI H226	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.49985
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52953
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15408
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3856
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07196884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81035
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.867
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202997
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07227
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62338
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE228619_0_v_1_cdh11_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7063
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55242
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4332
BRD-K02833343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46149
TFEB	ChEA Transcription Factor Targets	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14276
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286563
Fibrosis	CTD Gene-Disease Associations	1.0	1.56656
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17957
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63211
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948732
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30789
BRD-K87647164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4712
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1217
Pancreatic ductal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
polyamine metabolic process	GO Biological Process Annotations 2023	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3409
KMRC20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57017
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10003
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06649
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891162
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08369
Perturb_14041_KO_Mbd1/Mbd2/Mbd4/Mecp2_SRP337936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.28575
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45401
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01656
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06227
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96684
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51696
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0836
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6290138__F2	PFOCR Pathway Figure Associations 2024	1.0	null
ChIP_GCN5_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60625
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00882
phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24242
APEX1	MSigDB Cancer Gene Co-expression Modules	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3903
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02591
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09636
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09048
Rectal sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
BRD-K95264594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.98511
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959178
CBX3	ENCODE Transcription Factor Targets	1.0	null
sulindac sulfide-308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77797
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K12111274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94458
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12862
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894115
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM33_knockdown_304_GSE32903	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56928
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.55534
positive regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.458006
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59219
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74538
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15513
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.105
Oxygen	CTD Gene-Chemical Interactions	1.0	null
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06578
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.729797
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972048
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02897
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14743
regulation of lymphocyte proliferation	GO Biological Process Annotations 2015	1.0	null
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860758
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
EFM19	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12406
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50059
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70105
hydroxylase	GeneRIF Biological Term Annotations	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.36764
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Up_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989674
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01319
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19889
BRD-K85708426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41888
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24181
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14084
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.02821
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17932
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18087
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79228133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28031
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67795
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13092
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03215
BRD-K82883803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15933
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P4HA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00298181
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190495
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83451
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7913
peptidyl-lysine modification	GO Biological Process Annotations 2025	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52867
FM3A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25649
PMC3479095-pone.0047303.s002.xlsx-AA_catabolism-Gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Peritrophic membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.628697
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0507
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69480055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29086
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null