association	dataset	threshold value	standardized value
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66754
BRD-K82433264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15201
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36011
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1844
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A4-FUK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABL1	Hub Proteins Protein-Protein Interactions	1.0	null
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041669
DB	DepMap CRISPR Gene Dependency	1.0	2.02661
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31935
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26003
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17131
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC905	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97671
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.16572
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
BRD-K37516186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2144
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2687
axon part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HG3	DepMap CRISPR Gene Dependency	1.0	4.52956
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75082
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24777
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
BRD-K61551386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37878
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25251
MHH-CALL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22746
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18585
chr8_1113990_G_A_b38	GTEx eQTL 2025	1.0	4.49701
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915206
Choline	CTD Gene-Chemical Interactions	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05339
hsa-miR-4477b	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nmdareceptor	GeneRIF Biological Term Annotations	1.0	null
Perturb_1169_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71714
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4687-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5165
BRD-K01757377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35408
TCF7L2	ChEA Transcription Factor Targets	1.0	null
ASXL1	ChEA Transcription Factor Targets	1.0	null
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.73456
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K64183190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06724
Triglycerides	GWAS Catalog SNP-Phenotype Associations	1.0	0.449549
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57872
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CEBPB	ChEA Transcription Factor Targets	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2270_KO_lincBrn1b_SRP028547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08521
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21514
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050987
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.017
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10233
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.854295
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988707
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7714
MALME3M	DepMap CRISPR Gene Dependency	1.0	3.27123
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27048
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gilles de la Tourette syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
regulation of neurotransmitter receptor activity	GO Biological Process Annotations 2023	1.0	null
BRD-K31812476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.061
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.82225
Polyps	DisGeNET Gene-Phenotype Associations	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051811
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91899
BRD-K31969867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33104
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.05535
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
hsa-miR-3689d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.45711
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
BRD-K81921806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08903
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Tuberous sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03113
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32467
hsa-miR-3976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-302f	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952824
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895859
OVCAR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44712
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03093
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983997
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5556
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95131
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02057
ATXN7L3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02932
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K48294384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22589
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12443
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.03279
Alcoholic Intoxication, Chronic	DisGeNET Gene-Disease Associations	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
hsa-miR-606	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417337
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044005
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88539660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11474
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87259
axon	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
disease	GWASdb SNP-Disease Associations	1.0	0.082347
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90541
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39626
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.131262
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.959085
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9119
Basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.852
hsa-miR-5095	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77315
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850584
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93675
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05184
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bacterial extracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.1934
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869622
pheneticillin-5763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6603
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918725
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07272
RPS6KA3	Hub Proteins Protein-Protein Interactions	1.0	null
Thymus-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.934755
BRD-K13206026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10877
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01479
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06738
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3545
cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.529903
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26398
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857893
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKCB	KEA Substrates of Kinases	1.0	null
Metaphloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Perturb_1181_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.78212
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04836
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39227
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00047
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of immune serum protein physiology	GWASdb SNP-Phenotype Associations	1.0	0.646119
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.085349
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21589
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.472241
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Triglycerides Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70676
BRD-K44866331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18257
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11984
Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05793
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37462
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.79026
BRD-K15393664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42129
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833753
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853462
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24928
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.028
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927715
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hnf1b_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.170639
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.047366
hsa-miR-520e	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15627
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1796
hsa-miR-429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-3074-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36107
Protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
BRD-K43449580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85699
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92152
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849895
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27478
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.79774
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77374
hsa-miR-302d	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
BRD-K30228236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2605
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25515
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.499
Developmental Delay (Disorder)	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06218
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.60359
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2444
hsa-miR-17	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.624067
hsa-miR-30b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21055
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.958764
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.119002
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22212
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04745
BRD-K62312047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40663
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13615
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.13182
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33997327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07602
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11469
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03047
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.16728
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02946
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03127
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52515
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28143
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.80656
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cortical	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839532
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13812
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-30d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
JHESOAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83256
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plant candle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63257
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.965922
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35137
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4695-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
hsa-miR-3677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-767-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35216
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69658
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896551
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24174
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63008
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10425
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-320-HSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48637
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.46846
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.386425
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56019
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1106
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21659
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064666
BRD-K36764343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11116
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12501
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59847773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24746
hsa-miR-4440	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BT549	CCLE Cell Line Gene CNV Profiles	1.0	1.59879
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
Occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14624
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06371
BRD-K76067434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35266
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38586
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962554
Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296132
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8974
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09747
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1373
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CSNK2A1	KEA Substrates of Kinases	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35268
Tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
BZRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Athos	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKG1	Hub Proteins Protein-Protein Interactions	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18659
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74649
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	0.984113
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31623
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54692
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19802
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14685_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.9788
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.967372
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44674
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.48056
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.42637
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03085
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.843138
hsa-miR-363	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15393
T98G	DepMap CRISPR Gene Dependency	1.0	2.03194
PMC4686785__F8	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4704-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
HIF1A_01_348	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.80096
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957676
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
neuron-neuron synaptic transmission	GO Biological Process Annotations 2015	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.656
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07596
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295106
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04186
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63361
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951351
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39053
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868158
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955614
hsa-miR-371b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
BRD-K81447429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85321
NU-DUL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07161
JHOC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51064
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-4443	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903054
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10312
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54226
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25608
GRB2	Hub Proteins Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839196
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.046
HS936T	DepMap CRISPR Gene Dependency	1.0	2.50912
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64011
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.324851
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38661
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinitis pigmentosa 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25575
ST486	CCLE Cell Line Gene Expression Profiles	1.0	1.49878
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.15425
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZXDC_KD_GDS5070_504_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04482
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.861271
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895859
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_7_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Autistic Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02538
carbohydrate metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMBOX1_02_58	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.32193
Acute Myeloid Leukemia_LAML_TCGA-AB-2909-03A-01T-0744-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12091
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34579
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72659
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
white	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-450b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19463
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.78683
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K78623319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13515
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61207
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.162531
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82801
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41357
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
modulation of chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
preferential	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3526
KRAS.KIDNEY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3004
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34935
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24411
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24411
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892551
PRKCB	Hub Proteins Protein-Protein Interactions	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00483
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24698
NCIH841	DepMap CRISPR Gene Dependency	1.0	2.07895
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13054
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65325
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1422
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K34604637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42029
BRD-K65836113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85979
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.49534
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54381
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05954
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965971
cc81	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25156
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2675
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00069
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.66548
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02339
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.45668
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.38799
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5487
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05967
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01117
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77419
BRD-K77990919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10614
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.361691
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54198
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.46449
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
hsa-miR-548ah	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
hsa-miR-146b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01031
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.848784
Fatty Liver, Alcoholic	CTD Gene-Disease Associations	1.0	1.04611
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51904
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.58581
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
matter	GeneRIF Biological Term Annotations	1.0	null
Developmental and epileptic encephalopathy 52	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2408
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LMX1B_LMX1B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
hsa-miR-637	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
DOV13	DepMap CRISPR Gene Dependency	1.0	2.48731
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.611201
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593649
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25567
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97494
Panobinostat_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00652753
ZFP322A-24550733-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19298
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.01492
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38333
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66036
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51292
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951031
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73859
BRD-K54254994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72396
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40176
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
OVK18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62256
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082159
JHH4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55167
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-365-ZBED2_ZBED2	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04771
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915772
BB30-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.57711
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23338
hsa-miR-4663	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4786-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81419
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949389
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05385
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased locomotor activity	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857812
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.04645
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25767
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040264
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056809
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24347
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.180227
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57828
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62727
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06238
hsa-miR-4314	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CFPAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7165
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947717
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78994
hsa-miR-92a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93909
CESS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
BRD-K97994060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25535
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0667
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039344
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.880253
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985983
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28588
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.293
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.351
NIX_Deficiency_GDS2630_160_mouse_spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
C5orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39438
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899145
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839281
molecular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06823
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87323
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Primary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18245
BRD-K75206048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46529
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45225
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15138
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10108
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09194
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955946
BRD-K56343202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25847
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.901927
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
Tau burden	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49026
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Salivary_Gland-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.245602
BRD-K48744855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01097
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
LU65	CCLE Cell Line Gene CNV Profiles	1.0	2.01059
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22359
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5454
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051498
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10108
BRD-K30661365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17317
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K61199074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41176
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35145
nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.094822
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66593
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07119
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.2627
Body dysmorphic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888951
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98737
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937429
BRD-K41089262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07664
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.3257
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.25385
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.407856
SKLMS1	DepMap CRISPR Gene Dependency	1.0	3.07319
hsa-miR-1197	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25575
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K76521932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51768
RCOR2-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00285
Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2742312-1479-7364-3-3-221-S3.PDF-167-HLXB9_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08378
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905656
Centronuclear myopathy 6 with fiber-type disproportion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K28997108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05624
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969293
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1053
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.849992
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43428
Perturb_13377_KO_Sox10_SRP267687	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.40656
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34025
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981631
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23674
AD-70-DU18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25117
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58337
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10616
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5017
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08344
hsa-miR-377	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
hsa-miR-4700-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DT-061_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0656288
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94305
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858559
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SRC	Pathway Commons Protein-Protein Interactions	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.25138
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.35241
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869513
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45473
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75349
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23875
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K77718491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74094
hsa-miR-761	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
C80	DepMap CRISPR Gene Dependency	1.0	3.389
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30929
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48008
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10834
MYOG	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1299	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997619
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69025
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13253
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
substance dependence	GWASdb SNP-Disease Associations	1.0	0.399626
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047004
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4329	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
BRD-K93369639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52735
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_1W_vs_LS_1W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46871
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K83586473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17063
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001763
Methionine	CTD Gene-Chemical Interactions	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93923246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90598
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56274797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29354
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.82353
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865166
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18095
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896216
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.35924
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50618
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-4782-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15353
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45549
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09364
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-507	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.218679
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05484
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTSZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62451
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.12242
hsa-miR-3127-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69084
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833026
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63568
HOXC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04899
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92537
NCIH2009	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11348
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05507
BRD-K34910830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81715
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-516b	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
COR-L23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28986
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39092
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.939181
pimethixene-7426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96087
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9519
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48709
menstrual irregularities	GWASdb SNP-Phenotype Associations	1.0	0.400021
CSNK1E	Hub Proteins Protein-Protein Interactions	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002119
increased fasting circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.02235
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65884
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983673
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01696
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39227
Separation anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38031
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.313147
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	2.0564
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.060781
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.97534
GTF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43256
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941574
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
BRD-K22458526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19883
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Northern Epilepsy Syndrome	DisGeNET Gene-Disease Associations	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	3.1166
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.995837
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27682
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24046
BRD-K88195243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47367
abnormality of the menstrual cycle	GWASdb SNP-Phenotype Associations	1.0	0.827192
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09817
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72536
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27478
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48775
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42261
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-326	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Somatomotor areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31347
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95088
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949737
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.62985
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4983
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89728
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25373
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24446
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31397
GRIN2B	Hub Proteins Protein-Protein Interactions	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08554
hsa-miR-2467-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	1.0	1.80886
ALK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
sirolimus-6167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051819
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00484
18223198-Table3	GeneSigDB Published Gene Signatures	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.073815
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX3	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4311	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
BRD-K27529556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38024
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.224
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103499
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962554
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11928
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K02811477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54777
hsa-miR-4796-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03557
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.373328
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8817
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10727
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14459
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.541773
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01036
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63384
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03609
CDK2	Hub Proteins Protein-Protein Interactions	1.0	null
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849797
Perturb_5768_KO_Sip1/Nkx21_SRP010804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4856
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13991
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.75676
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46427
BRD-K48338059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12823
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.90321
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.82735
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916213
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94864
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3622a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.82652
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.358
OLIG2	ChEA Transcription Factor Targets	1.0	null
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01843
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48171
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07096
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01371
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14811
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216914
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55946794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09243
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10805
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73899
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77284
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.69577
BRD-K77144444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50376
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35665
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p2 part of the zona limitans core population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03978
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12534
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41633
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840231
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75137
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02739
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.96609
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1295	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
BRD-K84121706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03494
Dendritic spine membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08694
BRD-K64824710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88502
Nrf2_deficiency_GDS3406_156_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18418
BRD-K75429775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62353
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.507
DGCR6	Pathway Commons Protein-Protein Interactions	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7156
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63366
GSE220520_6_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75389
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89824
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888769
IMR32	DepMap CRISPR Gene Dependency	1.0	4.09549
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24387
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20383
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906321
BRD-K64836560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0281
COLO679	DepMap CRISPR Gene Dependency	1.0	2.35794
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971488
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048503
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.55019
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09718
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27414
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01239
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.976638
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.470822
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51757
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35145
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09725
SIN3B	ChEA Transcription Factor Targets	1.0	null
18062813-GeneList	GeneSigDB Published Gene Signatures	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03614
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08363
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09295
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54087
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47743
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.918494
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16898
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.96579
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27195
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45888
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040927
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.225
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21738
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948475
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89517
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
phenazopyridine-5758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39460811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00974
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24411
hsa-miR-3613-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43065
frontal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25185
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Acute Myeloid Leukemia_LAML_TCGA-AB-2949-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891072
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8410861-41467_2021_25544_MOESM34_ESM.xlsx-MCR-geneID_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067082
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848134
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6583
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09353
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46651
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
BRD-K07300437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2455
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08426
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00805
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
biliary tract disease	GWASdb SNP-Disease Associations	1.0	0.334694
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10686
DLGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-10a	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69373
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.56131
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33063
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05914
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045196
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
post-traumatic stress disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11921
BRD-K83783925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00107
C99	DepMap CRISPR Gene Dependency	1.0	3.35988
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900588
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51219
hsa-miR-4436b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUO9	DepMap CRISPR Gene Dependency	1.0	4.22756
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989649
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22532
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15491
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973402
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992817
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.38091
hsa-miR-4731-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
BRD-K38997615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70348
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.38061
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05756
REST	ChEA Transcription Factor Targets	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.64952
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043301
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63417
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63186
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98560805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11717
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Perturb_1183_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
mRNA_ZFAND3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46021
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941638
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114575
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF322	ChEA Transcription Factor Targets	1.0	null
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-93	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-323-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5952
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4546
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.795145
BRD-K77743611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73536
Diabetes Mellitus, Type 2	CTD Gene-Disease Associations	1.0	1.21984
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973402
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
ADHD and autism ASD pathways	WikiPathways Pathways 2024	1.0	null
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14085
BRD-K69248736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07191
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1432
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
bone disease	GWASdb SNP-Disease Associations	1.0	0.15267
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57559
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926761
globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421148
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999265
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854155
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19973
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.658
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19545
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08952
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K75915595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43808
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12963
hsa-miR-4667-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03179
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29683
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.859971
Immune stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
a2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12585
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39182
BRD-K74968522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1449
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337072
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58477
SAPAP family	InterPro Predicted Protein Domain Annotations	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58227
OUMS23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01183
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Age At Menarche	DisGeNET Gene-Phenotype Associations	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70254
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.91127
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29655991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13661
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946704
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991396
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7659
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.950367
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-4266	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17802
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973684
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905888
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973402
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.01617
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60611
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
SK-N-DZ	GDSC Cell Line Gene Expression Profiles	1.0	1.75344
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79455
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSK3B	KEA Substrates of Kinases	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-302e	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01748
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63391
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01022
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79246
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67696
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03519
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.91
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.10641
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6333
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.046874
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18555
NCIH1915	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57929
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
BRD-K57786028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18668
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05644
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955946
hsa-miR-3619-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.45968
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Triglycerides	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.62799
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06501
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	2.10291
BRD-K00537235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10744
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963786
SORBS2	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased lymphocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_5706_KO_Abcc8_ERP119268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55641
Perturb_644_OE_ERG_SRP344038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.18968
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57889
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65G-01A-21R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89885
Weight Loss	CTD Gene-Disease Associations	1.0	1.01512
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59442
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64307
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Trichotillomania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
biliary tract abnormality	GWASdb SNP-Phenotype Associations	1.0	0.45891
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02403042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46506
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3164
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886849
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39203
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36207
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.9885
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046435
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
sclerosing cholangitis	GWASdb SNP-Disease Associations	1.0	0.538104
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7913835__F3	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33827
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165655
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26916
TET1	ChEA Transcription Factor Targets	1.0	null
triglycerides	GAD Gene-Disease Associations	1.0	null
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11961
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38199
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FYN	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78202004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5121
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44577
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968408
SK-N-FI	GDSC Cell Line Gene Expression Profiles	1.0	1.55526
cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962979
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944662
CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23123734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63123
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02488
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NB13	GDSC Cell Line Gene Expression Profiles	1.0	1.88019
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14670_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15031
HCC70	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54233
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K53768630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03826
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46118
BRD-K51061297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1191
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80823
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.772313
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03809
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25874
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56477
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735559
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01059
increased neutrophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949463
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06232
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66055
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05285
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.361659
BRD-K02990757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43023
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110229
hsa-miR-4490	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564833
regulation of nervous system process	GO Biological Process Annotations 2023	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.58443
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2479
hsa-miR-4717-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11706
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12674
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94467
NCK1	Hub Proteins Protein-Protein Interactions	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17551
BRD-K99546030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66374
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0854
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.848465
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4273
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06152
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24026
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33506
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Clozapine-induced cytotoxicity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
AKT1	KEA Substrates of Kinases	1.0	null
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53838
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26672
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921054
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
KP-N-YN	GDSC Cell Line Gene Expression Profiles	1.0	1.53593
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09062
duodenal ulcer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.474877
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28706
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
induced hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.842188
BRD-K95860374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.257
BRD-K74399971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07757
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4835
BRD-K19106745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38975
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NLGN4X	Pathway Commons Protein-Protein Interactions	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
volume	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88362
Fatty Liver	CTD Gene-Disease Associations	1.0	1.33612
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06204
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95593113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38834
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
hsa-miR-371-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34386
BRD-K74314059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16872
BRD-K72424071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58999
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07008
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-513c	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
paternal	GeneRIF Biological Term Annotations	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22458
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55335
BRD-K64264170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44839
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.293504
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.09701
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.63063
JM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
NH-12	GDSC Cell Line Gene Expression Profiles	1.0	1.99709
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97368902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48687
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.846854
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37964
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
decreased lymphocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
imipenem-2873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-498	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMI1	ChEA Transcription Factor Targets	1.0	null
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Perturb_1170_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46371
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.967176
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960445
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25101
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.129511
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-135a	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9812
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRKACB	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.34884
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39448
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04809
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00284
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08959
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.879744
BEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50987
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K29543978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14687
hsa-miR-512-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
hsa-miR-1279	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
hsa-miR-4802-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03796
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83985
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955946
SHANK2	Pathway Commons Protein-Protein Interactions	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cystocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518859
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.68926
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37187
EOMES	ChEA Transcription Factor Targets	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.6301
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26655
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12032
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00467
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40985
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05177
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.768393
biological_process	GO Biological Process Annotations 2015	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873928
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15021
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.52204
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13747
BRD-K06611347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57305
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08864
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_4-Supplementary_Table_4A_Results_of_heterogeneity_test_of_single-cell_eQTL_MR_analysis_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06808
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959261
A253	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35144
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27682
PMC4791243-oncotarget-06-43452-s006.xlsx-Supplementary_table_S5-Supplementary_table_S5_Differentially_expressed_genes_in_TP53_mutant_versus_TP53_wild_type_cell_lines_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12991
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.0933
obsessive-compulsive personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-217	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937853
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890449
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051734
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27159
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559254
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7986
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08084
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07576
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55975
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987582
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33357
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	1.22288
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39567
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.453223
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23054
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.73256
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5067
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841465
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.113553
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12866
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1474
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hsa-miR-520g	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
BRD-K93457574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24735
BRD-K98062520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32334
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826322
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859487
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.061099
NCK1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844732
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840231
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC7029484-13041_2020_561_MOESM3_ESM.xlsx-Table_S8-Table_S8_The_extracted_upregulated_genes_in_SBMA-MNs_in_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16876
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
N syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888161
hsa-miR-520b	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12184
ROS50	DepMap CRISPR Gene Dependency	1.0	7.77761
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0749
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968278
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30874
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17973
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AKT1	Hub Proteins Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal social investigation	MGI Mouse Phenotype Associations 2023	1.0	null
PMC3729750-NIHMS493477-supplement-1.doc-9-Supplementary_Table_10a_Comparison_of_gene_expression_profiles_between_cases_with_activated_SETBP1_high_expression_and_mutation_and_SETBP1_lower_expression_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Phobic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-129-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
ZFP322A-24550733-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548n	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K71204648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60125
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Intrinsic component of postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41432
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06223
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PRKG1	KEA Substrates of Kinases	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12505
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.563
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11582
BRD-K96604397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25221
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79895
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BATF	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K21747676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46074
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22265
hsa-miR-4693-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982477
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.46674
BRD-K19011391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7734
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22189
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03922
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
RH28	DepMap CRISPR Gene Dependency	1.0	5.89757
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28814
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
regulation of postsynaptic neurotransmitter receptor activity	SynGO Synaptic Gene Annotations	1.0	null
coassembly	GeneRIF Biological Term Annotations	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985597
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-30a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27478
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07718
Corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.783
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43379
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12391
cholangitis	GWASdb SNP-Disease Associations	1.0	0.538104
Beckwith-Wiedemann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904309
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24052
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64464
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.878359
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873204
BRD-K96459367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21513
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75907
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.06296
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.389281
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45774
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11347
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0494
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34748
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78282
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01885
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.20521
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051184
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.79597
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18464
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955177
hsa-miR-1207-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
BRD-K68395284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00495
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14955
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04713
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039241
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5419
intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04777
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16704
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14024
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-557	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07829
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40113
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	2.29695
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36904
hsa-miR-365	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42993
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3591
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03924
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03948
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.49551
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056462
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14851
Menarche (age at onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
BRD-K41645779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.62671
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05365
NH6	CCLE Cell Line Gene Expression Profiles	1.0	2.04541
PANC0504	DepMap CRISPR Gene Dependency	1.0	4.50716
EOMES-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06063
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K39571490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12395
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6994
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238478
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79388
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
calcium- and calmodulin-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.23207
hsa-miR-4650-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882272
NH12	DepMap CRISPR Gene Dependency	1.0	2.2236
BRD-K68544484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65025
BRD-K99839793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01388
Lung cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965971
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07859
BRD-K49472569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68881
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03531
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0402
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93967
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A52933579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01656
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
Feeling miserable	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25575
BRD-K74862734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39716
LRRC7	Pathway Commons Protein-Protein Interactions	1.0	null
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K62841356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47211
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56663
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Lassa Fever Virus_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07027
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85335
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923198
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.959506
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03015
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58231
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.863119
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22174
hsa-miR-330-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945869
G401	CCLE Cell Line Gene Expression Profiles	1.0	1.4782
PMC7444072__F5	PFOCR Pathway Figure Associations 2024	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01298
GSK3B	Hub Proteins Protein-Protein Interactions	1.0	null
Drug-Induced Tardive Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K68746558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03026
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0776
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.628065
Dendritic tree	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.893
Vasculature-lymphatic endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.417891
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.889642
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39251
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494136
PAX6	ChEA Transcription Factor Targets	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5339
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11128
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.34847
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40406
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29125
SNU449	DepMap CRISPR Gene Dependency	1.0	2.04234
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dysplasia	GeneRIF Biological Term Annotations	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29415
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.213669
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9825
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970958
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3459
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
organelle part	GO Cellular Component Annotations 2015	1.0	null
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4144
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0497
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31275
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870274
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21892
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.849992
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5517
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24213
BRD-K82508779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58784
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35164
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3405
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2778
Weight Gain	CTD Gene-Disease Associations	1.0	1.04389
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00974
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873714
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
BRD-K75451592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15079
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47773
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15577
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
Stroke	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
schizophrenia ;  autism	GAD Gene-Disease Associations	1.0	null
PMC2665242-gkp077_nar-02582-s-2008-File011.xls-Sheet1-Supplementary_Table_5_Single_CTCF_binding_sites_identified_near_the_imprinted_genes_by_ECMFinder_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41433616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08731
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881451
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886341
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05793
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991202
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30743
puberty and gonadal disorders	GWASdb SNP-Phenotype Associations	1.0	0.354538
MOG-G-CCM	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74116035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09999
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51943
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67479
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991223
hsa-miR-429	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR2	ChEA Transcription Factor Targets	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Refractive astigmatism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
TAL1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43243
regulation of postsynaptic neurotransmitter receptor activity	GO Biological Process Annotations 2023	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
modulation of chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32263
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42736
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85414
Neuronal ceroid lipofuscinosis 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
neurofilament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
End-stage renal disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
Perturb_12050_KD_Mtss1_SRP185976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NB1643	DepMap CRISPR Gene Dependency	1.0	4.54388
HCC1171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38253
type 2 diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13110695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08361
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657725
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5355-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
CORL279	DepMap CRISPR Gene Dependency	1.0	2.78908
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr8_1148400_T_A_b38	GTEx eQTL 2025	1.0	2.31802
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.15831
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3908
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87742
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4793-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63267
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.528388
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20107
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP5_SP5	Rummagene Transcription Factor Associations 2026	1.0	null
H2803	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22248406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00496
T24	BioGPS Cell Line Gene Expression Profiles	1.0	0.866045
ZBTB33_02_82	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.35755
CNKSR2	Pathway Commons Protein-Protein Interactions	1.0	null
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3035
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17094
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.557
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMPA glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.399
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60119
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44548
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0836
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69034
CI-1040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1856
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BRD-K92144896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30615
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.39132
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21168
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-33a	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56843
fluspirilene-6662	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26245
SMC3	ENCODE Transcription Factor Targets	1.0	null
Sec61 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550106
Phelan-McDermid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23903
layer III of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44128
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04166
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased dendritic spine density	MGI Mouse Phenotype Associations 2023	1.0	null
17177833-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TMMY-2226-SM-4DXTN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11342283-mmc4.xlsx-LPS_vs_ATP_LPS-UCSC_RefGene_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_7-Supplementary_Table_7A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_late-diagnosed_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01733
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86231
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NB12	GDSC Cell Line Gene Expression Profiles	1.0	1.70083
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29167
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848282
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK2	KEA Substrates of Kinases	1.0	null
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22587
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2819
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82514
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-323b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862193
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01751
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.939181
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60841
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.34348
hsa-miR-25	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TE-16-VT54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307747
hsa-miR-3123	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.41379
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54316
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39002
CSNK1E	KEA Substrates of Kinases	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933894
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824346
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837001
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.64948
hsa-miR-510	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03846
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	1.0	1.39533
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03419
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51298794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88919
BRD-K36352298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18132
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43876
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928587
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23681
Necrosis	CTD Gene-Disease Associations	1.0	1.07234
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548e	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18851
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31881
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38859
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.42637
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.85466
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.06178
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13345
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0661
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-509-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
BRD-K06896230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.42624
Anchored component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970351
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	3.40789
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	5.41139
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Daytime nap	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.97212
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.748
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56832
FLI1	ChEA Transcription Factor Targets	1.0	null
JURKAT	CCLE Cell Line Gene CNV Profiles	1.0	1.74758
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.50417
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6112
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
HINFP_02_36	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.78136
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2384
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-499a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Post bronchodilator FEV1/FVC ratio	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8153
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850366
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02873
obesity	GWASdb SNP-Disease Associations	1.0	0.939181
hsa-miR-495	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907713
BRD-K93223696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11316
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABL1	Pathway Commons Protein-Protein Interactions	1.0	null
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02538
BRD-K50413145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65521
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04546
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960388
hsa-miR-501-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
hsa-miR-543	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507457
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45211
cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498048
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Protein-protein interactions at synapses	Reactome Pathways 2024	1.0	null
Ionotropic glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.496
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
peptic ulcer disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.296571
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54272776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21711
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17715
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15746
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51022
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53947
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039398
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2892
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neurofilament	GO Cellular Component Annotations 2015	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09671
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
BRD-K83836941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47464
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00117
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28552
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.170731
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04193
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87418410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25055
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2302
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07913
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TCF3	ChEA Transcription Factor Targets	1.0	null
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.85715
SK-CO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05349
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.41491
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07393
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25485
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17826
Arsenic	CTD Gene-Chemical Interactions	1.0	null
NB17	GDSC Cell Line Gene Expression Profiles	1.0	1.87418
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0395
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO783	CCLE Cell Line Gene CNV Profiles	1.0	1.95449
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1287
BRD-K03733288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16955
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07358
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63919
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093737
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84245
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10369
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97251
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55061
NB1	CCLE Cell Line Gene Expression Profiles	1.0	1.84704
PMC5260790__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00191
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Type IA spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00813
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	2.34699
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.01076
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Impulse control disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946177
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80883
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRK	Hub Proteins Protein-Protein Interactions	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.121103
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24749
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2766
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Schizophrenia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02516
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881339
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86854
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23114
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06666
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
EW-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18559
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998766
BRD-K87537204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13989
SNCA_KO_GDS4153_530_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.06919
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00034
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09689
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47675
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.144
hsa-miR-4766-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09844
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Narcolepsy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K75985122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16646
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81417
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56974
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72439355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4316
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71341
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.88255
hsa-miR-485-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
abnormality of the female genitalia	GWASdb SNP-Phenotype Associations	1.0	0.191376
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99553
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.51695
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00592
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
thoracic cancer	GWASdb SNP-Disease Associations	1.0	0.468272
Hyperplasia	CTD Gene-Disease Associations	1.0	1.20361
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29768
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11984
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54927
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23048
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03558
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.991
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872818
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.82545
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14059
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.49939
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906973
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19404
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05726
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LU65	DepMap CRISPR Gene Dependency	1.0	4.97707
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43184
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49139
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00284
GSE173873_12_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4158_KO_Mir137_SRP072457	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.32845
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941108
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K73834056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00853
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918087
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47335
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09963
BRD-K75900642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16206
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.05573
cerebral white matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922781
TRIM28	ChEA Transcription Factor Targets	1.0	null
RPS6KA3	KEA Substrates of Kinases	1.0	null
BRD-K67491390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63534
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21912
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14632
hsa-miR-367	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC9104818__F5	PFOCR Pathway Figure Associations 2024	1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14876
Obsessive-Compulsive Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24305
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31658
AE-67-FF84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.441866
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24603
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21332
BRD-K65860773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21519
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055942
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.03159
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06425
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924744
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
L1236	DepMap CRISPR Gene Dependency	1.0	7.03968
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
PMC11588066-pnas.2410331121.sapp.pdf-5-ZFHX3_ZFHX3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.60938
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BHT-101	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49745
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72694
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918287
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20372
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.705
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992174
KYSE-410	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09954
increased neutrophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
CSNK2A1	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47898
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951133
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.2434
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.322736
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97162
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47039
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42626
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85711
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09337
BRD-K65969715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16153
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1159
BRD-K76482408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36748
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49937
BRD-K58138729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04249
BRD-K51338042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16573
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08792
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Prestwick-864-3994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.00478
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
KCL22	CCLE Cell Line Gene CNV Profiles	1.0	2.09673
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06266
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44301
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.127581
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE410	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65456
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21408
MFH-ino	GDSC Cell Line Gene Expression Profiles	-1.0	-1.86705
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20872
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17235
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73673
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2836
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8158
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.760639
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
AA-18-GQ83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257714
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Basis pedunculi cerebri	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08849
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3358
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57369
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.232
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17719
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
J82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61816
NANOG	ChEA Transcription Factor Targets	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64814
BRD-K90660470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32262
BRD-K43992442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05097
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.22511
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.868615
BRD-K77172154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41647
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-591	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34465
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25323
PRKACB	KEA Substrates of Kinases	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.13992
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154011
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826216
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834078
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.916373
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.13827
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955946
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38413
hsa-miR-4717-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.253
BRD-K95125640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7024
possible	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4669	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K77797589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22743
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.485
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04474
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24745
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835759
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10656
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888706
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07434
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943222
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K41423946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18651
intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.6281
NB6	GDSC Cell Line Gene Expression Profiles	1.0	2.11064
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47433
Mental Retardation	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.40699
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.35032
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHP-134	GDSC Cell Line Gene Expression Profiles	1.0	1.62802
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38396
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K43905345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3733
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11474
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57428
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849135
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2386
GRK5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60421
hsa-miR-373	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49308
Triglycerides	dbGAP Gene-Trait Associations	1.0	0.15617
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04742
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-502-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.07625
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05242
hsa-miR-509-3-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5139
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68949
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.37189
SISO	DepMap CRISPR Gene Dependency	1.0	3.3425
CAL33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9293
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30217
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.341
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8206
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.902122
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12535
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04382
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.881464
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CA-72-UL91_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212943
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87213
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826692
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19096
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41025
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.7029
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20161
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990483
hsa-miR-302b	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.317639
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63926
PMC5112273__F2	PFOCR Pathway Figure Associations 2023	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22742
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44383
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.27706
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92705
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39893
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CASKI	DepMap CRISPR Gene Dependency	1.0	2.47077
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940975
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.42343
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19836
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00805
hsa-miR-548b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K95551067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88818
hsa-miR-200b	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46283
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_9880_KD_RUNX1_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.71907
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19269
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PMC12763974-13148_2025_1988_MOESM1_ESM.pdf-19-ZNF334_ZNF334	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73265
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17911
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19769
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955986
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2196	GDSC Cell Line Gene Expression Profiles	1.0	1.47328
hsa-miR-548a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.00507
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17305
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5394
16849537-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.536
hsa-miR-146a	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.554732
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
BRD-K55857083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24907
PMC12532594-41380_2025_3119_MOESM1_ESM.pdf-132-CREB3L4_CREB3L4	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925342
hsa-miR-581	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.961216
KDM1A_KD_GDS5055_367_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
cellular process	GO Biological Process Annotations 2015	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873504
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.52853
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
glutamatergic synapse	GO Cellular Component Annotations 2025	1.0	null
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01486
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29173
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8234
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57872
PMC5112273__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
EZH2	ChEA Transcription Factor Targets	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20012
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15574
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNCA_KO_GDS4153_445_mouse_Striatum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Childhood disintegrative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.7114
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051527
Learning Disorders	CTD Gene-Disease Associations	1.0	1.20719
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00656
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918287
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K17155259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1367
fragile x syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.548971
BC-12-VG35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298584
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11821
nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308612
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15297
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.039
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826704
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05933
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22015
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K57650037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56894
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.065998
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.28266
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.22625
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.12133
hsa-miR-302a	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1194
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14161
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58
Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Myosin IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29086
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863148
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848384
PIK3R1	Hub Proteins Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1584
ZNF143_02_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.96166
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23967
HT29	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43483
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4686785__F8	PFOCR Pathway Figure Associations 2023	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99978
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62569
RUNX1	ChEA Transcription Factor Targets	1.0	null
BRD-K60794504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45281
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3104
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824746
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13497
CORL105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.457
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05033
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.68807
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.26018
thiethylperazine-6154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neurexins and neuroligins	Reactome Pathways 2024	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-3143	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23711
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35191
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.15532
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44129
KP-1N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31521
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78882
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25371
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64277
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.88632
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_3-Supplementary_Table_3_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_ADHD_significant_association_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.372
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32431
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.27395
BRD-K38787519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21475
increased aggression towards mice	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-3188	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18585
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3209
Wolf-Hirschhorn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294939
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12122
hsa-miR-3679-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.333979
NB6	DepMap CRISPR Gene Dependency	1.0	3.4857
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K72687327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46077
Perturb_5372_KD_MED13_SRP094120	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.66617
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.639
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
synaptic membrane	GO Cellular Component Annotations 2015	1.0	null
Mobitz type II atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41922
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.793562
glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46413
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67968
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62053
RNF2	ChEA Transcription Factor Targets	1.0	null
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54353
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39588
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17838
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-589	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22158
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51022
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09337
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067988
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98147
Neuritic plaque	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
abnormal miniature excitatory postsynaptic currents	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.25861
hsa-miR-3977	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882019
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
Postsynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.391
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	4.2405
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9205
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838852
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6697
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.431
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15063_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.9993
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24006
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88834
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
BRD-K25525067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05604
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09168
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04432
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40321
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842393
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6262
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054704
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69229416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02786
intermediate filament	GO Cellular Component Annotations 2015	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.939181
SET2	DepMap CRISPR Gene Dependency	1.0	2.85951
Timothy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.06919
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28581
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37069
cell junction	GO Cellular Component Annotations 2015	1.0	null
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00416
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.7991
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06336
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64762
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10565
BRD-K07420629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04343
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947048
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041975
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4540	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16336
hsa-miR-33b	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
hsa-miR-1233	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
H3K27me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.909
NIX_Deficiency_GDS2630_655_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
neurofilament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.302912
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.06919
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BICR6	CCLE Cell Line Gene CNV Profiles	1.0	1.5333
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77419
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09221
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27077
C2BBE1	DepMap CRISPR Gene Dependency	1.0	3.53916
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K81281620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16873
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K62324460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00086
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.50685
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1449
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84035
abnormal neuron physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K60144139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00806
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
EGR1	ChEA Transcription Factor Targets	1.0	null
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3198
BRD-K72681425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.01194
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14071
SF172	CCLE Cell Line Gene CNV Profiles	1.0	1.38834
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-2115	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
neuron-neuron synaptic transmission	GO Biological Process Annotations 2025	1.0	null
hsa-miR-20b	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
hsa-miR-10b	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
PBX1	ChEA Transcription Factor Targets	1.0	null
sulmazole-4009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956129
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54638
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56841
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20536
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36893
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
hsa-miR-1343	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.07919
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13258
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05245
BRD-K01039605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16627
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17568
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3333
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887036
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988059
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937975
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00938
NCI-H526	GDSC Cell Line Gene Expression Profiles	1.0	1.49574
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40617
nucleotide-excision repair factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.562
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6778131-41467_2019_12494_MOESM13_ESM.xlsx-Figure_S3b-BCL2-MYC_Day_75_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12705
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.03554
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC7913835__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	0.476802
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77121
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20019
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	1.0	1.60701
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19205
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12773
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
resected	GeneRIF Biological Term Annotations	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.0963
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
MCC13	DepMap CRISPR Gene Dependency	1.0	2.7434
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.14112
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55504273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20849
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97638
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03838
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28594
Somatodendritic compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65467
hsa-miR-3612	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908061
Intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14121
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.67
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SRC	Hub Proteins Protein-Protein Interactions	1.0	null
Retinitis pigmentosa 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870502
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
snps	GeneRIF Biological Term Annotations	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45385
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.19108
epileptogenicity	GeneRIF Biological Term Annotations	1.0	null
Oppositional defiant disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.226
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02134
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K66511507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16007
hsa-miR-30e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47644
MCC26	DepMap CRISPR Gene Dependency	1.0	2.87797
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880778
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80617
RUNX3	ENCODE Transcription Factor Targets	1.0	null
increased fasting circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20466
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14224
COPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05969
YAP1	ChEA Transcription Factor Targets	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58480962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01822
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89102
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896216
Eye morphology	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.709691
neuron-neuron synaptic transmission	GO Biological Process Annotations 2023	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02243
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04091
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64416
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16348
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46736
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	1.54163
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-650	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1681
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988123
CRK	Pathway Commons Protein-Protein Interactions	1.0	null
MKN28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50467
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19903
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11554
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05937
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.06919
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MFM223	DepMap CRISPR Gene Dependency	1.0	4.44783
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3218
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04649
abnormal postsynaptic density morphology	MGI Mouse Phenotype Associations 2023	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.96093
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852535
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-4524	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6194
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6117
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3068
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33889
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06462
Cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87161
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04864
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60474
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85515
BRD-K07536006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26346
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45628
BRD-K48764596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19704
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ca9-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87017
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.824302
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCF3	ENCODE Transcription Factor Targets	1.0	null
BRD-K73177528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06723
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	5.54562
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30932
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
glutamatergic synapse	GO Cellular Component Annotations 2023	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4687
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08114
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intrinsic component of postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
allele	GeneRIF Biological Term Annotations	1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
NCIH1792	DepMap CRISPR Gene Dependency	1.0	2.67918
COLO684	CCLE Cell Line Gene CNV Profiles	1.0	1.50204
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.841809
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97407
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60038
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14543
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
FYN	Hub Proteins Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87912
hsa-miR-2110	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30113
insulin resistance	GWASdb SNP-Phenotype Associations	1.0	0.426397
hsa-miR-3927	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF1_02_26	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84552
TT	GDSC Cell Line Gene Expression Profiles	1.0	1.44555
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26088
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67937
PMC12198892-pi-2025-0101-Supplementary-Material.pdf-14-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08818
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56622
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48051
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.42637
abnormality of female internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.191376
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20332
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23093
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57805
Perturb_303_KD_Cd109_SRP078564	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59096
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82553
abnormal synapse morphology	MGI Mouse Phenotype Associations 2023	1.0	null
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18955
DLG4	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25104
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00276
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73597
BRD-K62358193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38429
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82987
BRD-K45245001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91229
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-2278	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
TGW	GDSC Cell Line Gene Expression Profiles	1.0	1.43069
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08975
Perturb_123_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.2715
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
BRD-K50149147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02953
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984174
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062506
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09586
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55717
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74484
hsa-miR-3909	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-1183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE146074_1_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-214	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
BRD-K76729384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29851
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE173873_12_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05077
hsa-miR-372	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24453
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.226262
abnormality of the biliary system	GWASdb SNP-Phenotype Associations	1.0	0.167808
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.800336
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872152
bone resorption disease	GWASdb SNP-Disease Associations	1.0	0.468272
hsa-miR-129-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.15865
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28272
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.714
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.167
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.194157
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42546
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10737
U2OS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38421
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44264
BRD-K04714488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37615
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45432
hsa-miR-3185	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11613
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57872
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09358
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20792
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4801	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43819
increased eosinophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71101
BRD-K32718856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65089
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962578
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.0555
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18461
hsa-miR-196a	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-196b	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12662
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.216111
synapse part	GO Cellular Component Annotations 2015	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05955
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
ECC10	CCLE Cell Line Gene CNV Profiles	1.0	1.38312
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08321
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51395
BRD-K26140483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58079
BRD-K71496240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.95799
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066929
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4325	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36496
increased eosinophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
NatA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2335
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045618
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brugada syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44476
autism	GAD Gene-Disease Associations	1.0	null
imprinted	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61668
Language disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53299
BRD-K75381775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0589
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6194
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1788
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6141
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857254
RCOR2-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	2.13764
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07307
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13258
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.706
hsa-miR-4678	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31347
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06364
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
postsynaptic density, intracellular component	SynGO Synaptic Gene Annotations	1.0	null
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34186
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07292
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_1175_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1155
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
modulation of chemical synaptic transmission	SynGO Synaptic Gene Annotations	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_8-Supplementary_Table_8A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_persistent_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CSNK1A1	KEA Substrates of Kinases	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78787
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33325
Cannabis dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.793562
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34442
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hallucinogen dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0788
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1024
hsa-miR-3162-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_2_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25575
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.697689
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
hsa-miR-514b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
hsa-miR-1185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lsm1-7-Pat1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.51
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87439
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.94325
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17322
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.28047
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
18223198-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_2163_KD_Chd8_SRP062904	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.95496
hsa-miR-548f	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879784
PK45H	DepMap CRISPR Gene Dependency	1.0	2.00125
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056606
hsa-miR-200c	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08214
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23322
regulation of trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09586
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17842
Postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
PMC8330021-13058_2021_1455_MOESM8_ESM.xlsx-MSC_HEATMAP-Unnamed_0_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65995
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.90644
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.835
subunits	GeneRIF Biological Term Annotations	1.0	null
Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.81347
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950911
hsa-miR-4700-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.476802
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
prefrontal	GeneRIF Biological Term Annotations	1.0	null
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Autistic Disorder	CTD Gene-Disease Associations	1.0	2.88009
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.407856
BRD-K77392050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1915
SHANK3	Pathway Commons Protein-Protein Interactions	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06962
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50427
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05041
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1951
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893262
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01004
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13497
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_6-Supplementary_Table_6A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_Childhood_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888645
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833209
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
Inflammation	CTD Gene-Disease Associations	1.0	1.1294
hsa-miR-520h	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52924
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19855
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86384
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07189
GP5D	DepMap CRISPR Gene Dependency	1.0	2.34056
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84552
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19033697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28619
15902281-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78015598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1498
BRD-K71221636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20437
BRD-K94277689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38292
hsa-miR-548g	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11748
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83812
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.39327
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06974
cancer	GWASdb SNP-Disease Associations	1.0	0.55372
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	3.2822
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19855
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238478
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23056
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.252
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
overnutrition	GWASdb SNP-Disease Associations	1.0	0.468272
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44826
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17381
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.186811
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54556
G361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49715
hsa-miR-320e	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-520d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.30096
SHI1	DepMap CRISPR Gene Dependency	1.0	2.24706
hsa-miR-499-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.535
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8329
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
ADRB1	Pathway Commons Protein-Protein Interactions	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9347
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45146
PMC5260790__F3	PFOCR Pathway Figure Associations 2023	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
focal	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1726
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64409
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55074
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09596790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0035
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46684
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.06919
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31114
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
testis	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42742
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50801
BRD-K60584379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17069
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	2.06398
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060717
BRD-K94801143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92856
Intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
hsa-miR-520a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.566
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04649
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3778
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.814
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883175
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953336
hsa-miR-32	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976401
MEL270	DepMap CRISPR Gene Dependency	1.0	4.16838
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30828
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9292
hsa-miR-3975	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
Glutamatergic synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223419
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.027833
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08633
Perturb_12544_KO_Ctnnb1_SRP194249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.8583
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.990644
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97101
neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05925
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-331-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.860123
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46939
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.309012
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.36751
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7123
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883508
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46805
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27236
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40298
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06666
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886383
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Postsynaptic specialization	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K58270905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59173
BRD-K68160857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43233
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p2190	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
Health literacy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87886
BRD-K63209730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98784
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70823
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98643
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.114222
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15377
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPK8	Hub Proteins Protein-Protein Interactions	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.93794
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLG1	Pathway Commons Protein-Protein Interactions	1.0	null
bile duct disease	GWASdb SNP-Disease Associations	1.0	0.334694
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095258
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70986
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7115
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nr1	GeneRIF Biological Term Annotations	1.0	null
Translation release factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
BRD-K97617600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39488
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16602
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42351
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72492
SW1990	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1386
SCLY	ChEA Transcription Factor Targets	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13473
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867943
BRD-K33200274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26303
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.20139
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51276
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1803
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.556
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.8675
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995105
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839196
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.992
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.649
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25185
PFSK-1	GDSC Cell Line Gene Expression Profiles	1.0	3.58284
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LB2518-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74227
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3682-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12774
Speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81738
A253	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
MJ	DepMap CRISPR Gene Dependency	1.0	6.04973
BRD-K76175734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0379
Intrinsic component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4719	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
postsynaptic density	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Neuronal System	Reactome Pathways 2024	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Downstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.06919
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
UMUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34982
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50271780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24562
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04909
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86442
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-502-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45712
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896112
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20012
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918287
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0381
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.976677
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78795
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73828
BRD-K66907139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36665
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-20a	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07506
hsa-miR-4779	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3214
White matter microstructure in first episode schizophrenia (right posterior cingulate cortex)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
tissue	GeneRIF Biological Term Annotations	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHSA0108	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8039
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17909
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08175
BRD-K68383485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13412
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964354
BRD-K25895238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25095
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.274361
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34064
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.4348
SW1271	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
breast cancer	GWASdb SNP-Disease Associations	1.0	0.939181
SNU761	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71419
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13592_OE_Mir322/Mir503_SRP348669	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19941
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12021535-CPH4-15-e70011-s001.xlsx-S21-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
susceptible	GeneRIF Biological Term Annotations	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90592
TEAD4	ChEA Transcription Factor Targets	1.0	null
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0958
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897228
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23204
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20093
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.38269
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.322736
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892455
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2928
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24313
cortex	GeneRIF Biological Term Annotations	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.664611
hsa-miR-3609	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00014
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.849051
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07965
hsa-miR-106b	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
RCC-JF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2453
A549	DepMap CRISPR Gene Dependency	1.0	2.46741
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Response to cognitive-behavioural therapy in anxiety disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1628
NOS1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-92b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3414
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888706
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14768
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.091563
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53766
CREB1	ChEA Transcription Factor Targets	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08745
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23582
BRD-K88960810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07232
brain	GTEx Tissue Gene Expression Profiles	1.0	1.38114
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0889
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.15578
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0257
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
AICD_Induced  expression / Over-expression_GDS1979_288_human_SHEP-SF neuroblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416043
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72858
BRD-K64509231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74243
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6088
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37154
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25147
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43851
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13058
Dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.895
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
streptomycin-3195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08433
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.042207
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886538
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02223
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70312
GTEX-XBED-0726-SM-4GIAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-520c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00312
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW982	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60446
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03372
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22274
PMC7444072__F5	PFOCR Pathway Figure Associations 2023	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.25512
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55408
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03088
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	0.912586
BRD-K35789946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34283
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77682
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17295
SUZ12	ChEA Transcription Factor Targets	1.0	null
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63500288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58543
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02134
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
JARID2	ChEA Transcription Factor Targets	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	1.01185
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5683
osteoporosis	GWASdb SNP-Disease Associations	1.0	0.939181
Asperger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05634
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01827
Isodicentric Chromosome 15 Syndrome	DisGeNET Gene-Disease Associations	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876889
epileptic	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-106a	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21587
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.424
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2847
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925622
abnormal spatial learning	MGI Mouse Phenotype Associations 2023	1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961179
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3864
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12328
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9927
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.95419
hsa-miR-503	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07086
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WM983B	DepMap CRISPR Gene Dependency	1.0	2.54869
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001625
hsa-miR-3622b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06223
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malformations Of Cortical Development	DisGeNET Gene-Disease Associations	1.0	null
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38752
molecular_function	GO Molecular Function Annotations 2015	1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-519d	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
lipid metabolism disorder	GWASdb SNP-Disease Associations	1.0	0.793562
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2497
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5113
vascular disease	GWASdb SNP-Disease Associations	1.0	0.152557
BRD-K70870890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16604
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72409
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05823
CP-320650-01-3825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22328
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15849
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84033
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5163
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04637
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07379
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1565
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
MCAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55628
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.2806
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.689964
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03144
GSE250518_0_v_2_trpm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868514
HMGN1_02_79	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.0
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
HCC56	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37979
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841983
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0162
hepatobiliary disease	GWASdb SNP-Disease Associations	1.0	0.187261
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05698
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50483
HMGN2_02_20	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.70044
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28986
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43523
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-885-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12274
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51826
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.963
Psychotic Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42605
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20864
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11312
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71591
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14096
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11024
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K64763803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03342
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
SNUC5	CCLE Cell Line Gene CNV Profiles	1.0	3.24339
BRD-K63730594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.182
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.119002
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34694
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0727
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
hsa-miR-616	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863439
BRD-K38084509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80439
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31798
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.47955
BRD-K12702054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2271
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.9227
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02009
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28819
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Child Development Disorders, Pervasive	HuGE Navigator Gene-Phenotype Associations	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58338
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69607079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11291
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.4986
BRD-K67137502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40947
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
situ	GeneRIF Biological Term Annotations	1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08841
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33801
BRD-K91104058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3649
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07397
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.050826
BRD-K05535086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15768
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.26485
BRD-K70153099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00416
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.809817
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.879744
hsa-miR-30c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12043
hsa-miR-302c	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27938
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881642
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84812
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02009
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895985
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	DepMap CRISPR Gene Dependency	1.0	2.09127
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839967
Tardive Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07286
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5624
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39539
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09337
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.8894
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K27302831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75999
dementia	GWASdb SNP-Disease Associations	1.0	0.407856
ZXDC1_KD_GSE45417_686_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84685
postsynaptic membrane	GO Cellular Component Annotations 2015	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	3.81576
hsa-miR-516a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54397
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02943
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.94
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2505
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Atypical autism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17659
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60394
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13686
BRD-K24271020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22346
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50312
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03948
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
NCI-H1755	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14224
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01618
hsa-miR-4418	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
artery disease	GWASdb SNP-Disease Associations	1.0	0.202491
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34308
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21656
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.59681
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17908
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39699
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19114
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20271
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67912
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89332
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98111
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7397
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12133
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4143
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78221
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18414
demonistrated	GeneRIF Biological Term Annotations	1.0	null
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96096
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.39
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29822
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00349
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12644
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45284
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99852
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.100119
hsa-miR-1225-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
Neurofilament	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37189
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70115
BRD-K27472340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10901
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17013
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47776
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28603
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK8	KEA Substrates of Kinases	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6697
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.439
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9103
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47307
BRD-K64474460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56108
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.706598
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.68848