association	dataset	threshold value	standardized value
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68972
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58328
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33941
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12422
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00815
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.137
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00045
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.076
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12077
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23512
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4691
PMC5503627-oncotarget-08-39497-s003.xlsx-hyper_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07909
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93463
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34596
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74282
GSE217363_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55932
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8453
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30988
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21913
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02664
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9903
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7255
GSE244072_10_v_7_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58907
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of Arp2/3 complex-mediated actin nucleation	GO Biological Process Annotations 2025	1.0	null
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91471
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56256
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9299
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61178
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXD13_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28948
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26758
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
Astroglia	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8425
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24454
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21947
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28063
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91949
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85735
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.868
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7159
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4226
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2249
GSE126127_2_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Macroglia	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE83145_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-36-ENSG00000128645_HOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39062
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03914
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03906
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Motor proteins	KEGG Pathways 2026	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6666
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63559
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87843
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79301
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of actin nucleation	GO Biological Process Annotations 2025	1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09905
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0486
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63368
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.918
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX4_CDX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9298
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95858
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2015
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62788
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0835
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2053
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24289
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.225
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74114
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67025
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18597
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01089
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GDF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16482
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
cilium movement	GO Biological Process Annotations 2025	1.0	null
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10633
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1316
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10798
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79664
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61601
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4051
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87531
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04254
H3C10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02311
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Posterior silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10213
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28951
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11661
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dynein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13298
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37317
Blond vs. brown/black hair color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8725
Axonemal dynein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9759
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0737
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	3.63898
PMC7613740-EMS124720-supplement-Suppplementary_Tables.xlsx-S6_Immune_evasion_signature-Table_S6_Genes_comprising_IES_displayed_as_RTT_vs_NTT_up_and_downregualted_seperately_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58298
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38024
PNT-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3947
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54514
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13434
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3702285-cddis2013211x6.pdf-46-PLAG1_PLAG1	Rummagene Transcription Factor Associations 2026	1.0	null
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04723
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11963
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27716
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Las1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.879
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3138
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78968
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7993
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43718
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42821
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29623
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8029
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.586
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0383
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05607
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.247
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63719
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6377
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57319
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
Gastrodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.875
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06278
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17877
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02709
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1242
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36925
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_30min_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56861
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1395
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28876
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.527
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55363
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10677
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80658
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.242
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1579
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08757
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXB9_HOXB9	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8723
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1707
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90157
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4548
GSE231875_0_v_1_zbed3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32546
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82795
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25765
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5659
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1855
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09606
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spinal cord	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29331
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9325
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
GSE173405_3_v_0_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78173
GSE193282_3_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43818
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Astrocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45725
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01535
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27683
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06435
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5029
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07579
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201454_1_v_2_ftcd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX2_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4295
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-36-HOXD1_HOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.12806
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2168
PMC11839199-CPR-58-e13746-s001.docx-3-RUNX2_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40599
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09043
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8326
GSE183251_7_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6881
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95933
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04694
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04897
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33929
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78157
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68621
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6156
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of Arp2/3 complex-mediated actin nucleation	GO Biological Process Annotations 2025	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0229
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05295
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36908
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24345
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
GSE126463_4_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11651
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08145
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4393
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Upper tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39395
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56042
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25815
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22201
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87591
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05009
Glial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00228
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6123
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Astroglial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6296
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05998
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78411
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47326
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
axonemal dynein complex assembly	GO Biological Process Annotations 2025	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner dynein arm assembly	GO Biological Process Annotations 2025	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
G57321FI	GlyGen Glycosylated Proteins	1.0	null
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4965
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60092
Pupal wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138024_2_v_0_rgs4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4757
cilium movement involved in cell motility	GO Biological Process Annotations 2025	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25408
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16965
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.483
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
PMC11324510-41587_2023_1949_MOESM3_ESM.xlsx-Supplementary_Table6-Supplementary_Table_6_TP53_pathway_genes_list_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testicular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1469
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9198
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35833
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral sucker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
PMC5322933-pone.0172430.s013.xls-Pathways_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RASIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11537
GSE195559_2_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.73
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
PMC5630028-supp_gr.220533.117_Supplemental_File_S7.xlsx-TP53_core_genes-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77994
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.41161
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27004
PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.035
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9397613-can-21-1692_supplementary_table_s8_-_12_supps8-12.xlsx-S12_Gene_expression-TP53-Supplementary_Table_12_Gene_expression_correlating_with_TP53_sgRNA_enrichment_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11173
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of cell differentiation	GO Biological Process Annotations 2025	1.0	null
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18104
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29201
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8349
regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr1_85061252_A_ATTAT_b38	GTEx eQTL 2025	1.0	1.01488
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03898
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11854
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8856
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7199
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10895040-Table_1.XLSX-Table_S8_-_mapped_genes-Table_S8_Positional_mapped_genes_of_110_IVs_for_pairs_of_microbial_features_and_MM_with_significant_P_value_in_two-sample_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3723
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92667
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39015
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99949
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0916
A549_Carmofur_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00874618
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5073
PMC5322933-pone.0172430.s013.xls-Immune_MSC_Single_Basal_vs_MSC-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37213
regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA7_HOXA7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05353
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61041
dh82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.483
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.347
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01301
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5313
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71872
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3472
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02215
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53663
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2528
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of cell motility	GO Biological Process Annotations 2025	1.0	null
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4548
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97338
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
negative regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66904
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.362
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55954
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63893
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.97
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07963
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
Vitellarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4877
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13361
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25497
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43023
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23421
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1487
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73999
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
chr1_85117640_T_A_b38	GTEx eQTL 2025	1.0	1.43693
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.089
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.112
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82876
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52051
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stereocilia tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12452
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21119
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29586
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15408
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9317
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68523
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59813
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41893
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50383
GSE134986_2_v_8_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39962
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.735
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8342
ACBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10691
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29824
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2269
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2471
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Middle silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56625
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4584
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44397
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.088
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Pick body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-374-TWIST1_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Inner dynein arm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46252
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51306
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
PMC12532594-41380_2025_3119_MOESM1_ESM.pdf-124-ST18_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EVX2_EVX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE62843,GSE64370_0_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1473
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10308
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56592
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.108
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51947
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.045
Sperm individualization complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.981
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3932
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86499
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36469
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3352
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05901
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22466
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48436
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72231
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42617
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.65
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60657
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35598
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36737
Progressive supranuclear palsy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185953_2_v_0_tlr3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11699
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.988
Ependymal cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4122
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27667
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cilium-dependent cell motility	GO Biological Process Annotations 2025	1.0	null
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33821
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10693
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0563
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.867
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08034
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glia	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5322933-pone.0172430.s013.xls-HG_MSC_Single_Basal_vs_MSC_AD_B-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.035
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
inner dynein arm	GO Cellular Component Annotations 2025	1.0	null
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88181
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.062
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52866
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD51C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20577
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59401
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91484
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04882
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25104
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01291
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17674
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5322933-pone.0172430.s013.xls-Oncopath_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.812
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4741
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43037
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_29_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74478