association	dataset	threshold value	standardized value
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98271
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83663
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25811
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00806
Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
GSE113221,GSE113968_4_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85298
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.48097
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12088
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978355
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9334
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55466
Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974306
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4368
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20179
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05605
Perturb_4504_KO_Hoxa1_SRP174196	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.4642
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903189
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42128
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5638
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06294
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42172
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11427
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846169
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44249
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04325
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90611
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62731
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38549
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03387
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07991
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89035
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87787
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0986
increased sterol level	MPO Gene-Phenotype Associations	1.0	null
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66278
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2781
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2694
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56106
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873648
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0544
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13759
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06828
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2793
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6471
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
496100394_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21368
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48708
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
increased circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1678
NCIH2444	CCLE Cell Line Gene Expression Profiles	1.0	1.4334
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52934
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824554
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70216
Oropharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4726
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5756
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56139
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19205
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.117
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
increased circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2081
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01118
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99375
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73813
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4929
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053315
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37368
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6092
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.001878
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70853
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32537
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.46113
UT7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22404
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7807
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67102
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.293
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17454
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76685
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39095
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05171
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72789
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93529
GSE199541_2_v_5_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TDRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98516
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89977
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69417
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
H4C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40948
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42208
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39391
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.15666
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4644
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04604
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65915
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86801
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.88699
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7415
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864019
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975665
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969102
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1723
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30439
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77792
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29933
Large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6097
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2267
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01591
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82451
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.311
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21144
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.44785
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894286
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31971
hsa-miR-198	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28236
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40092
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20166
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18609
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7458
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.88451
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7869
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09675
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00882
NCIH526	DepMap CRISPR Gene Dependency	1.0	5.50405
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69336
GTEX-S4UY-1326-SM-4AD4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0815
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00829
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9334
hsa-miR-4745-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.934582
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894685
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1314
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28024
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35378
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
hsa-miR-485-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0118
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49491
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49872
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54099
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94572
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09136
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32906
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949973
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05459
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.73309
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23095
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0804
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.732983
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92766
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07794
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2851
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30911
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869753
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3622b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5944
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08812
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10611
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.35643
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.05968
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72601
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18725
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2083
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
NCIH226	DepMap CRISPR Gene Dependency	1.0	4.29319
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91419
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910166
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28766
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17821
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52937
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68933
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01765
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77687
hsa-miR-4436a	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48022
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
PLD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04502
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70054
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15046
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8465
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46711
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996779
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20412
LN229	CCLE Cell Line Gene Expression Profiles	1.0	1.58154
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.48333
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32014
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22202
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19153
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33267
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57896
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47935
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5916
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931434
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40092
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26068
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39521
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0459
npBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29253
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00474
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988487
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
KASUMI1	DepMap CRISPR Gene Dependency	1.0	4.14534
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63699
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37004
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53553
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
TE1	CCLE Cell Line Gene CNV Profiles	1.0	2.21363
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sec62/Sec63 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22663
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5392
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60358
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06862
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964696
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65123
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12539
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86258
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978309
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03232
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.4508
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
Perturb_13277_KO_Bach1_SRP238575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67987
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.9091
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45193
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44327
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9718
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46462
MPP89	CCLE Cell Line Gene Expression Profiles	1.0	1.54297
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.3587
FOXC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9445
EWS502	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5165
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93703
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92286
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826694
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00427
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34028
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4982
MXI1	ENCODE Transcription Factor Targets	1.0	null
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87096
PECAPJ34CLONEC12	DepMap CRISPR Gene Dependency	1.0	3.84386
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932441
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64204
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39391
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863221
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072372
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.45288
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8312
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43355
abnormal cholesterol homeostasis	MPO Gene-Phenotype Associations	1.0	null
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13933
Cortical subplate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07164
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	3.71242
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54022
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2301
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94402
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866455
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874336
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12731
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63174
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01687
CBY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97427
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.99379
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88491
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10535
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92997
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86538
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1678
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48257
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.81112
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07882
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00102
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985211
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35183
ZNF384	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00993
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41948
Endopiriform nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22533
PEO4	DepMap CRISPR Gene Dependency	1.0	4.37675
LMNA_02_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12928
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48428
hsa-miR-3065-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972324
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
18927283-Table2b	GeneSigDB Published Gene Signatures	1.0	null
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34861
Pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0871
HCC1937	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67218
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03412
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	2.49313
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4323
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SF767	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60757
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	208.986
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831337
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.7243
PaCa-44 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76884
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20235
G-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420535
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945711
SNU719	DepMap CRISPR Gene Dependency	1.0	5.13421
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79362
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945711
SUPHD1	CCLE Cell Line Gene Expression Profiles	1.0	1.43865
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980821
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60389
TE5	CCLE Cell Line Gene Expression Profiles	1.0	2.04853
TSFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29092
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02202
Kidney Chromophobe_KICH_TCGA-KO-8416-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926557
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0798
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0732
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618
Perturb_8834_KO_MESP1_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1193
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847318
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2834
HT1376	DepMap CRISPR Gene Dependency	1.0	3.09312
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46016
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05806
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38527
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03863
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30776
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43446
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0771
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28519
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48786
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80197
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05206
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830877
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6701
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10214
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F	MotifMap Predicted Transcription Factor Targets	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4639
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01637
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31693
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26631
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	3.98968
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22947
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48129
NCIH2171	DepMap CRISPR Gene Dependency	1.0	2.31949
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55327
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
TNNI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13165
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18621
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.704
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90018
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32183
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36061
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36448
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48664
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25902
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21527
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38401
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83116
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.976501
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996779
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
sublayer 6b of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61067
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.80723
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14227_KO_Lsd1_SRP064569	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
esBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47097
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5729
ZNF723	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47333
hsa-miR-4725-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91543
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.3264
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43301
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
LAMTOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51372
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8363
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.117
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9614
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883305
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69724
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871181
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.54948
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3449
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943629
colo800	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953042
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78362
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828618
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rlc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
colo857	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872035
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15873
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99873
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7027
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23855
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12674
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	1.0	1.47103
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06116
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39476
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13119
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.889346
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00877
heart	GTEx Tissue Gene Expression Profiles	1.0	1.0169
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03766
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829593
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02093
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0407
abnormal circulating lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03266
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
HH	CCLE Cell Line Gene CNV Profiles	1.0	1.35895
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1404
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8284
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01
A3KAW	DepMap CRISPR Gene Dependency	1.0	4.57686
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86335
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29961
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75961
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11863
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935676
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47126
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09521
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64968
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98773
KMS21BM	CCLE Cell Line Gene Expression Profiles	1.0	1.62765
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23533
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71518
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36715
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.327
PMAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90098
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79305
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.936396
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07413
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836129
DnaJ domain, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42127
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06196
Nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6972
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.4063
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.924
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883194
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05957
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40568
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57247
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45593
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15303
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.72152
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888326
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1634
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959315
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08002
SLR26	DepMap CRISPR Gene Dependency	1.0	2.15279
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93809
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11534
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96323
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55821
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4199
BC3C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63639
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07944
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97687
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897188
BICR16	DepMap CRISPR Gene Dependency	1.0	4.4337
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08915
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15014
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_02_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.88264
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60662
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13667
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90444
hsa-miR-4481	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18322
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57647
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56599
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80091
EW8	DepMap CRISPR Gene Dependency	1.0	6.1547
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1051
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32322
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.71087
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829553
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51264
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80705
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859811
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6552
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49274
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12885
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9311
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895637
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95838
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951997
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34579
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81137
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47663
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53046
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.59064
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60832
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951947
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03521
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05195
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71627
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52428
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-612	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993058
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863624
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69208
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17695
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82285
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17876
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07362
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963981
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88569
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878177
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25876
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71736
EZH2	ENCODE Transcription Factor Targets	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60993
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4586
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09707
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27261
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46834
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38832
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Follicular thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876109
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
hsa-miR-219-1-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17436
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98661
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876728
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5425
Perturb_7151_Mut_RNF43_SRP237436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.78965
hsa-miR-4432	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3243
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19518
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39627
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9077
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0413
Lung adenocarcinoma_LUAD_TCGA-78-7159-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25587
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.65434
microphthalmia	IMPC Knockout Mouse Phenotypes	1.0	null
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
BICR56	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3767
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91592
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907378
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45137
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83248
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48486
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46391
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38062
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71451
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69478
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2421
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40497
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44222
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43074
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4828-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10944
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01694
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44202
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88292
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7337
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69464
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.94267
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15227
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35473
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09129
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78218
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26253
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01646
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62757
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18346
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.96879
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50747
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09347
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1652
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879994
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24768
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5441
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40204
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14013
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.11854
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38252
NCIH854	CCLE Cell Line Gene Expression Profiles	1.0	1.42916
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06362
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08497
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35879
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050189
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7376
TAL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922567
JHH6	DepMap CRISPR Gene Dependency	1.0	3.81757
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91618
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10082
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26933
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932981
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94546
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16255
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20814
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22947
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04967
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824631
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0836
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84413
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
hsa-miR-1285	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63108
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993682
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32537
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82491
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.984497
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08892
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08684
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08517
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82804
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1187
MKN45	DepMap CRISPR Gene Dependency	1.0	2.13844
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83116
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29257
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25257
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22103
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15462
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4443	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73862
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03014
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06456
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934632
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3368
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02479
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
MYC	ENCODE Transcription Factor Targets	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0045
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32379
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5841
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41346
OCIAML2	DepMap CRISPR Gene Dependency	1.0	3.65657
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55979
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95208
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00518
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	2.12293
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840593
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
USP2_KO_GSE43517_20_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87179
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876873
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53416
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15792
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02975
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67989
G-402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44794
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41944
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08054
COLO775	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47163
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14844
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20098
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967577
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10208
nBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875453
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.975129
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39391
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04548
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17956
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0606
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21161
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850148
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837157
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4473
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CORL47	DepMap CRISPR Gene Dependency	1.0	3.10415
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87475
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853682
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07605
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07924
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.506
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.66651
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
SYCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50365
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
GPRC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82693
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07309
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48516
STAT3	ENCODE Transcription Factor Targets	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32537
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4285
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21027
hsa-miR-4723-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9286
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.124
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89867
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20014
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93612
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40092
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.694
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983927
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50858
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.32582
GTEX-WOFM-0726-SM-3MJF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18921
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941394
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72493
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0056
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99949
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45916
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66389
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.07599
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02849
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42393
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971823
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857956
increased circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0529
abnormal lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
sublayer 6b of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15782
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29839
Perturb_5566_KO_Sorbs2_SRP221026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.46313
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931827
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6116
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993041
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1795
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8859
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2904
TBL1XR1_02_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.28011
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.46985
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88657
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93607
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13728
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.38527
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7706
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829593
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
Autosomal dominant limb-girdle muscular dystrophy type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3204
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57789
MFE296	DepMap CRISPR Gene Dependency	1.0	2.0533
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8845
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29533
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.95922
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08359
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25598
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47935
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1786
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72579
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949627
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26636
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	4.42647
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05367
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
hsa-miR-1288	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967249
abnormal glucose homeostasis	MPO Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894278
GABARAPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2442
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92746
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40714
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7992
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832932
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882219
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.5198
HCC78	DepMap CRISPR Gene Dependency	1.0	4.15005
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06867
Exopher	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
PMC12754469-ab-25-0159-Supplementary-1.pdf-18-HLF_HLF	Rummagene Transcription Factor Associations 2026	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21187
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966908
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00253
H4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92703
ZNF439	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56004
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38977
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.67234
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23405
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91127
TCCSUP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35285
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57337
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
CCK81	DepMap CRISPR Gene Dependency	1.0	2.55075
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1799
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1051
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72035
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71248
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35778
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79102
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4586
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51932
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57138
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64585
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.99315
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24275
SIRT6	ENCODE Transcription Factor Targets	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20967
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960741
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848507
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03086
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82304
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.63543
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74455
increased fasted circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15238
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34134
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3686
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.762
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.03416
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940511
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04658
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46016
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83778
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.019
ATP5MK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1848
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23625
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840341
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944477
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18245
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875218
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1262
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43257
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62018
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79866
PECAPJ49	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9354
abnormal circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64005
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61359
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78507
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6126
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4092
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01096
WD-62-UB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281456
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82522
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16055
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06196
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18174
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856265
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32837
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11053
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955572
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0106
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41082
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26347
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958453
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89655
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78086
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.228
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17998
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879299
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63376
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85386
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896937
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924648
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910072
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995274
abnormal circulating free fatty acids level	MPO Gene-Phenotype Associations	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78963
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29657
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.826429
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.545
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68672
NCIH1694	DepMap CRISPR Gene Dependency	1.0	3.3176
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38214
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9179
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
calcitriol_homo sapiens_gpl570_gse35925	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
CCDC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2788
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07837
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75253
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858955
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06974
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9756
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.98147
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62389
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49761
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4358
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98641
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
DnaJ domain	InterPro Predicted Protein Domain Annotations	1.0	null
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51013
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07272
psn1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9579
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7327
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75988
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71243
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19992
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14071
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06752
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33461
GTEX-W5WG-1026-SM-4LMIF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956996
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906803
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15099
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883305
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
hdlm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
CW2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7529
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07694
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867974
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.36146
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.47453
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54189
increased cholesterol level	MPO Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906737
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04253
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.155
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79559
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83024
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03545
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4747
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.02195
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87544
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70008
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82836
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925422
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03521
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983418
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.79978
LOX-1_OE_GDS4262_435_human_HAECT - aortic endothelial cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
valproic acid_homo sapiens_gpl6244_gse23909	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6281
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38787
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866726
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59356
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.3264
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67789
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853786
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20967
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7328
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23191
abnormal fatty acid level	MPO Gene-Phenotype Associations	1.0	null
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50747
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2557
Lung adenocarcinoma_LUAD_TCGA-50-5066-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983984
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77892
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38224
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50283
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05501
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94047
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29846
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13672
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73628
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.189
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93801
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32536
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903508
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.16581
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4659
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.8693
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78021
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04013
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03113
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11719
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20633
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.061
TCP1_02_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71919
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852088
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12223
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03554
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92711
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14071
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69274
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61853
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19492
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909143
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21055
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.52153
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905231
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834773
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
Kidney Chromophobe_KICH_TCGA-KL-8326-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal free fatty acids level	MPO Gene-Phenotype Associations	1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90252
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15609
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11637
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.561
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.50699
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07556
EP300	ENCODE Transcription Factor Targets	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86011
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12396
hsa-miR-105	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-4268	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.30151
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56611
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03548
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15703
ncih1650	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36193
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39842
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987332
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.16993
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46875
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67134
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16392
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70196
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30003
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920382
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95176
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22234
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89093
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70646
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74959
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02329
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6698
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15565
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14492
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9074
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78449
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02007
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40968
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65964
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861891
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930716
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09334
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2964a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78733
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90198
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86811
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1478
USP2_KO_GDS5079_25_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19298
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971205
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77081
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2567
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.522
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06867
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5729
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80978
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
hsa-miR-1256	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
NOBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10526
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65943
SW403	DepMap CRISPR Gene Dependency	1.0	6.53356
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81295
PSN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06355
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50594
OS252	DepMap CRISPR Gene Dependency	1.0	2.08719
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22127
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TBX5_TBX5	Rummagene Transcription Factor Associations 2026	1.0	null
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65054
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64093
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75458
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40092
Hypopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28165
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4139
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.69492
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04299
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75001
KDM1A_KD_GDS5055_367_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70021
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44267
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25548
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50566
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13173
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11979
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.53476
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06704
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20704
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06196
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04348
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4297
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8707
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65101
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49783
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935869
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2642
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3675
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.848
central subpallium (classic basal ganglia)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20643
hsa-miR-4744	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050142
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79801
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45263
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490409
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27478
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60718
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83851
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91925
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.769401
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31456
NMCG1	DepMap CRISPR Gene Dependency	1.0	2.20965
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75371
Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44053
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67036
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.92035
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29156
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6198
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
ro82w1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03069
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9004
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
MHHNB11	DepMap CRISPR Gene Dependency	1.0	3.08413
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01428
C4II	DepMap CRISPR Gene Dependency	1.0	2.8248
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06476
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92851
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12789
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19691
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99363
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91535
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.45965
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45901
HCC1806	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26676
hsa-miR-4797-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15658
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13298
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05357
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.780188
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11979
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54223
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40654
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80803
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07733
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7626
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0107
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07263
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0134
SJSA1	DepMap CRISPR Gene Dependency	1.0	2.42111
CMLT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84719
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7022
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15975
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54338
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64663
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72483
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64339
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05196
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55568
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43807
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25732
GSE151612_4_v_10_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58907
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4523
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.78051
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32071
FOXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52507
1321-N1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15773
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96858
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99512
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.88259
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal cholesterol level	MPO Gene-Phenotype Associations	1.0	null
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51766
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0659
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19105
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.1645
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2561
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05067
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.91964
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61639
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48915
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5992
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17059
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05883
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal fasted circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408987
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19114
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.848
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80143
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8304
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
NCIH2122	DepMap CRISPR Gene Dependency	1.0	2.60155
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37496
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72395
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87463
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20127
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46802
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.6982
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70855
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050189
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85478
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933342
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953715
increased fasting circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3532
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8054
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59852
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88129
BIRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73755
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.685588
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.35553
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29322
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982139
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20211
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5729
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98532
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09012
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01319
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06413
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11619
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54834
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39833
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03509
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.3264
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2903
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8465
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58582
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.06623
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1022
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947387
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21228
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28097
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08569
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03259
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39162
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76814
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0665
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	3.25896
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90885
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21279
juvenile-onset Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39842
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828419
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74839
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5129
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21055
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985252
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70214
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92081
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45219
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03128
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89089
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855337
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2132
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26914
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976678
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
EGR1	ChEA Transcription Factor Targets	1.0	null
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.45571
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9405
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3183	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19201
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40561
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982518
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08573
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5658
hsa-miR-526b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Protein processing in endoplasmic reticulum	KEGG Pathways 2026	1.0	null
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.721161
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.63715
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12736
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21655
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09581
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66235
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28178
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32988
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.28129
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03141
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06726
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59837
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97073
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75269
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
microphthalmia	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14904
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48001
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17448
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0382
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25876
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917551
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4935
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849284
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03876
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936359
MKN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66939
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06234
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98873
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6027
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05918
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832247
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941292
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12237
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967805
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5554
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6272
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60589
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83855
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72042
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05761
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5406
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97263
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26831
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41879
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5669_KD_Yy1_SRP281855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06036
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916247
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51859
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.43331
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20183
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842793
hsa-miR-3180-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6092
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9726
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30529
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40559
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52193
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30169
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06903
RNF167	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19541
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50213
decreased fatty acid level	MPO Gene-Phenotype Associations	1.0	null
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.60673
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35994
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9248
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23527
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10889
CNS cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86994
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999257
ZFP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50094
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41423
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6517
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16651
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5815
EFM19	CCLE Cell Line Gene Expression Profiles	1.0	1.81027
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949187
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40437
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39842
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84548
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.38396
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17486
Dhori Virus_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.15515
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89955
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12799
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0118
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12446
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19508
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41477
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22322
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92109
EI24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08351
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21361
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05203
Perturb_14494_KO_Igsf11_SRP320670	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.3321
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67725
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13473
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00371
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03554
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13031
hsa-miR-3187-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44065
Field CA1, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14713
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07751
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8968
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.48171
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4918
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86326
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.82993
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17335
BGC823	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36316
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848069
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24046
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911861
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65782
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872035
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
postcentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887719
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06114
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80888
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04716
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81695
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.56822
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92091
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57797
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943918
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47993
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26692
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95263
N syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81356
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91011
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0756
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7171
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8106
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23948
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01882
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3526
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837639
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03325
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
EGR1	ENCODE Transcription Factor Targets	1.0	null
PL4	DepMap CRISPR Gene Dependency	1.0	2.6015
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oropharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Tsu-Pr1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7141
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6997
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48702
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
COLO-699 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44085
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76175
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14423
PMC8567035-CTM2-11-e578-s001.xlsx-ATF6-SEC61A1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987711
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05158
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9334
ATG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39016
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86147
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02438
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44561
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872035
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43765
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907293
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42819
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10889
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
PMC6855629-pone.0225186.s003.xlsx-Sheet1-DEGs_repressed_by_MEIS1_in_human_cell_lines_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12452
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81436
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64744
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33564
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.32006
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3068
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73797
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.70194
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858841
decreased circulating free fatty acid level	MPO Gene-Phenotype Associations	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	5.75335
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4832
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
increased circulating insulin level	IMPC Knockout Mouse Phenotypes	1.0	null
MAPK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4306
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17654
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27953
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15703
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20619
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29821
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ST6GAL1_Deficiency_GDS3151_608_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19249
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.406
S117	CCLE Cell Line Gene Expression Profiles	1.0	1.3948
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33992
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.36052
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92738
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Cerebral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0033
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24179
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14777
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63268
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88927
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17788
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08507
Endoplasmic reticulum Sec complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0416
abnormal circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58051
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56213
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20419
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35714
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4614
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01366
hsa-miR-504	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38811
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37716
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61052
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923586
Preeclampsia_Placenta_GSE4707	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97201
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8067
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50531
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26831
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5748
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36977
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45632
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83778
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31547
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82629
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.92965
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28814
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67954
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10308
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22638
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33294
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6701
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78
increased fasting circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.15244
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52074
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89009
SKBR3	DepMap CRISPR Gene Dependency	1.0	11.6156
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33995
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98125
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31735
SNU16	DepMap CRISPR Gene Dependency	1.0	2.93493
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2637
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09662
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47933
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Z-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86643
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.42934
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949057
K562	DepMap CRISPR Gene Dependency	1.0	4.97909
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62768
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26868
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18661
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal circulating lipid level	MPO Gene-Phenotype Associations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1288
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.882645
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43597
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	2.42743
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13323
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
mRNA_ZFP281_18757296	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
J82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50288
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90444
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
TP53	ChEA Transcription Factor Targets	1.0	null
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52705
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
increased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
E2F4	JASPAR Predicted Transcription Factor Targets	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00213
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
UQCRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9447
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75334
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54667
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78362
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79687
CBX2	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83264
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03528
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01022
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884067
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38977
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949032
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77336
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05082
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07912
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877586
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33962
SCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70917
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8605
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48166
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03141
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37898
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896815
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02484
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24902
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00827
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04689
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92823
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8298
PMC7777191-pnas.2007991117.sd03.xlsx-E2F1_Q6-PROBE_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88578
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1817
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.35802
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51413
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78406
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01319
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0447
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938651
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33744
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.59482
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10554
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986836
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880779
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06627
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25235
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5584
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38405
ZNF585A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58656
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86377
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0289
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90766
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.910545
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72541
layer 3 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01318
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947667
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41067