association	dataset	threshold value	standardized value
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7488
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28436
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.321
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5532
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2806
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1121
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17641
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXD11_HOXD11	Rummagene Transcription Factor Associations 2026	1.0	null
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30218
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32171
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13133
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12374
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224249
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1585
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1139
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02198
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217371
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0186
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62406
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0452
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21879
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.8628
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50158
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08782
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21347
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9119
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75606
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482808
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35394
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18534
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70365
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2962
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23119
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73571
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25481
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4751
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31748
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51194
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0445
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05899
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14987
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6759
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20145
PMC10929187-ijbsv20p1547s4.xlsx-JQ1-dep_ATF4-XBP1signature-ABCC9_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.002
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48326
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.496249
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
PMC9691391-7945884.f3.pdf-113-ENSG00000251192_ZNF674	Rummagene Transcription Factor Associations 2026	1.0	null
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78086
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2012
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.951
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6153
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0856
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3668
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49379
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4312
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418207
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43117
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4841
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31892
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36886
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4127
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.798
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08818
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_0_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.473
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41616
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58643
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24087
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7275
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03393
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4674
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86726
GSE175920_0_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.178
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5202
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3603
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19549
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6529
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00167
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25341
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.53242
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17296
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8133
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3117
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9113
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11394
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63766
GSE163282_12_v_2_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204179
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4471
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01323
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14539
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9505
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19664
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0114
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17371
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1121
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77898
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1337
PMC3500769-srep00875-s3.xls-PAX2-Time_1_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5355
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02507
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8183
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27337
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37779
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399307
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04381
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31967
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28002
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81862
GSE129244_0_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1906
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4526
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14021
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13241
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7084
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10706
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55757
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74825
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50834
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21695
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01084
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3544
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354444
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11427
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00923
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2749
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442394
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71962
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2587
PMC8044433-mmc4.xlsx-Sheet1-Acute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19165
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68588
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7632
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03827
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02664
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45523
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22908
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7365
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1031
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6504
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7985
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8349
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7429
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313857
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2518
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02299
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60203
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14492
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7145
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14503
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9883
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25307
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08178
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2498
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7915
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52986
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0141
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3899
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2641
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7317
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4693
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273701
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1026
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.38
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9712
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07529
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42419
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4485
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2953
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6091
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.903
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39436
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8317
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04234
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3008
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13625
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1911
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2383
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11284
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44708
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01622
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69143
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23359
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230212
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8984
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.757
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34185
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6468
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31679
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0733
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91679
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61044
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3152
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7197
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8577
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80889
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33239
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6208
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2168
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4158
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88402
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10821
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12221
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62086
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08421
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.2789
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02304
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.774
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2033
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3381
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8989
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF367	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55612
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0737
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5968
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5661
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22452
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06944
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14071
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4060771-170289.f1.pdf-557-SLC2A4RG_SLC2A4RG	Rummagene Transcription Factor Associations 2026	1.0	null
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06074
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1338
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0264
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03119
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8556
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203173
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15825
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7414
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0875
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5159
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33598
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3517
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20675
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0101
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6509
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4785
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50147
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8318
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7372
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2963
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247896
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23821
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4745
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-PHF1_mod_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5558
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87211
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01898
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06688
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2581
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56938
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4052
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90437
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0366
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6172027-elife-38795-fig2-data2.xlsx-XBP1_RNASeq_only-Gene_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01557
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.626
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45497
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35162
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.08
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34897
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2592
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00139
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.849
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57038
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8214
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0297
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9469
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0298
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11032
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4752
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18447
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6245
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25162
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5279
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01713
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44047
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32395
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53402
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1511
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06144
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8793
PMC7925689-41467_2021_21687_MOESM10_ESM.xlsx-A_HIF1A-Unnamed_8_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ELOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19454
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96517
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7454
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82494
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.631
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212102
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9464
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5539
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239698
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30889
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1161
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03955
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0316
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82563
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8643
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8102
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11991
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41711
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9422
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8511
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244447
GSE164726_0_v_1_phf10_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36619
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15591
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Body mass index (change over time) in lung cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1648
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4127
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2959
GSE128634,GSE128636_1_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58343
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2224
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27123
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59935
GSE112860_5_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTSZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68006
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2163
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3681
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06461
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6815
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22117
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6521
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8752
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57021
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75535
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0492
CMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07751
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5736
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1143
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06929
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.12
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_NOT_Autophagy_NOT_GSE41177_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54714
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02933
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.56492
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274063
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9445
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09993
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6915
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05934
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08992
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29862
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5974
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7671
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19078
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3026
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6401
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08537
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.507
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06867
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4489
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39052
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7256
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52626
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07305
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9582
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6802
PMC12079334-ADVS-12-2501734-s002.pdf-140-ENSG00000213928_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0294
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03822
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26029
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6207
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1146
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1064
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1631
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77099
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33197
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2364
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4682
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2858
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06169
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2326
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18782
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.567443
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13049
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3706
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.764
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210804
RANBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06518
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215718
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57919
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9124
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5371
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04366
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1869
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30683
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65849
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4213