association	dataset	threshold value	standardized value
female infertility	MGI Mouse Phenotype Associations 2023	1.0	null
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08049
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259591
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74885
Embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.058
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01453
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45738
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16071
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.049
Seminoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.62
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57488
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87819
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9306
SMARCA4	ChEA Transcription Factor Targets	1.0	null
female pronucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68955
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4663
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883827
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85664
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.48205
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41815
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22863
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51934
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09907
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53498
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4907
GSE129648,GSE129650_2_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56761
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
pronucleus	GO Cellular Component Annotations 2023	1.0	null
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81567
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64087
regulation of dna demethylation	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38907
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80563
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36712
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68685
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2199
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86802
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Cell lineage map for neuronal differentiation	WikiPathways Pathways 2024	1.0	null
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
WA-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65349
cellspecific	GeneRIF Biological Term Annotations	1.0	null
Urogenital ridge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05019
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12083
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40591
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51934
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.956
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0898
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85145
male pronucleus	GO Cellular Component Annotations 2023	1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041148
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47241
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.297
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.673518
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60093
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33528
17880687-TableS3	GeneSigDB Published Gene Signatures	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23279
Trophoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30148
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16189
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05317
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2901
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.343799
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179636
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37635
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042314
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05814
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4992_KO_Mettl5_SRP268611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.31308
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.288829
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9959
Perturb_13229_OE_Klf5_SRP341620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.44984
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5421
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37757
insulin-responsive compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3977	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_17704_KO_Pds5b_SRP365503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.7941
pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.6638
Cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2948
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.458
Perturb_13257_KO_Pcgf3_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.41559
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.71233
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9681
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909593
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Embryonic carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Perturb_5715_KO_Chaf1a_ERP006640	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7755097__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Pre implantation embryo	WikiPathways Pathways 2024	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
NANOG	ChEA Transcription Factor Targets	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20176
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5429
Embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.669
NNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36245
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4614_KD_Etv5_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.73362
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942981
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
Mitochondrial cloud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
Testicular cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05567
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3296
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895616
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66316
Teratocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.831
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12272
after	GeneRIF Biological Term Annotations	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Late endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07324
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4264
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0494
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.181
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.35182
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45587
GSE101859_1_v_0_rhoj_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839744
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54115
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
Testicular cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
blood	GTEx Tissue Gene Expression Profiles	1.0	1.10018
HCC33	CCLE Cell Line Gene CNV Profiles	1.0	2.10042
Fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3566
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02891
abnormal epigenetic regulation of gene expression	MPO Gene-Phenotype Associations	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
ChIP_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96207
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Developmental pluripotency-associated protein 3	InterPro Predicted Protein Domain Annotations	1.0	null
UMC-11	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Amniotic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85855
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.784407
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
KMS-11/TKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0672
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.60383
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35451
biological_process	GO Biological Process Annotations 2015	1.0	null
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30735
hsa-miR-181a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54477
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0528
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.353662
Ragulator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.191
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4347
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
Childhood germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1228
NOY-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
XPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81688
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978003
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70495
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4093
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8133
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45213
Perturb_8994_KD_CCDC144NLAS1_SRP135858	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26908
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6677
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.036
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3867
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41271
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09414
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25089
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995177
Sin3-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33725
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DVL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52389
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90579
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06275
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11228
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841749
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03147
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23223
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.673
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
intracellular part	GO Cellular Component Annotations 2015	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21672
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8721
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77363
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72606
KLF2-18264089-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Peritubular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66597
methylated histone binding	GO Molecular Function Annotations 2025	1.0	null
Distal arthrogryposis type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
PMC7672319-mmc2.xlsx-Stemness_MSigDB62sel_gmx-KORKOLA_CORRELATED_WITH_POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.199
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.02971
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23093
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
germ cell cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45239
PL4	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100503
chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.395485
mammalian	GeneRIF Biological Term Annotations	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84957
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17499
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78893
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.578
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_5039_KD_Smarca4_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6128
496100475_TCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56145
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60027
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
testicular cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76553
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28648
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07952
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
KLF2	ChEA Transcription Factor Targets	1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89857
PMC5783456__F2	PFOCR Pathway Figure Associations 2024	1.0	null
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32226
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.23919
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.644788
Adrenocortical carcinoma_ACC_TCGA-OR-A5K6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4778
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11462
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.3415
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895616
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043443
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111429
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9586
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOX-1_OE_GDS4262_435_human_HAECT - aortic endothelial cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0235
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7951
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97541
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993256
CEP95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78202
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
male pronucleus	GO Cellular Component Annotations 2025	1.0	null
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45204
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3937
Cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71623
UM-UC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58209
mRNA_PANCT1_22327834	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64943
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31731
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23184
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36726
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of chromatin organization	GO Biological Process Annotations 2023	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72964
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9861
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.282
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4074
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3922
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.6964
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.389
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444884
epigenetic programming in the zygotic pronuclei	GO Biological Process Annotations 2025	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.823
Perturb_5349_OE_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.1113
Chromatin modifications during the maternal to zygotic transition (MZT)	Reactome Pathways 2024	1.0	null
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23663
Interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.50771
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92479
TRIM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60757
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04052
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.97935
Uterine wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.111
Butyrates	CTD Gene-Chemical Interactions	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30228
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37864
embryonal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.706754
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF709	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37849
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2327
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
Perturb_17701_KO|KD_Pds5a|Stag1_SRP365503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
hsa-miR-4732-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Malignant teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51934
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
demonstrate	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909315
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5411
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
Borderline personality disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055213
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.956361
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PcG protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.871
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.252202
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6122
NANOG-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
female infertility	MPO Gene-Phenotype Associations	1.0	null
Primordial germ cell_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040343
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.064
infertility	MPO Gene-Phenotype Associations	1.0	null
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.11
Perturb_13210_KO_Mbd3_ERP001253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81719
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4331
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56753
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841749
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8211
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48339
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
NCI-H2087	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43535
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
cleavage	GeneRIF Biological Term Annotations	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476589
Endodermal sinus tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.069
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.50468
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pronucleus	GO Cellular Component Annotations 2015	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54079
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10314
effect	GeneRIF Biological Term Annotations	1.0	null
Perturb_6627_KO_TEAD1_SRP315348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08643
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48022
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52334
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.70558
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-NTera-2-Genes_deregulated_in_NTera-2_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05075
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28366
Anovulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188034
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.491791
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75209
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
NCI-H2170	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indispensable	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864486
Rectum adenocarcinoma_READ_TCGA-AF-6136-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4242
KLF4-18264089-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
Umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
TMEM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82243
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Perturb_4527_OE_Hk2/Pkm_SRP052789	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4023
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14457
Primordial germ cell_Undefined_Human	CellMarker Gene-Cell Type Associations	1.0	null
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64522
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9499
Amnion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.608
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7067
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33504
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18699
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39923
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97025
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864792
TCF3	ChEA Transcription Factor Targets	1.0	null
PPARGC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83415
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
differentiation	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.907355
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308867
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_POU5F1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE173810_4_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14719
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0279
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07419
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2717
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20941
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
Sarcoma_SARC_TCGA-DX-A1KZ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_12121_KO_Aire_SRP250736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.983
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03237
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417337
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
female pronucleus	GO Cellular Component Annotations 2023	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.522
Ovarian surface epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
Cancer, Embryonal	DisGeNET Gene-Phenotype Associations	1.0	null
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95107
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13471
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3969
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.894
cellular process	GO Biological Process Annotations 2015	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232029
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82646
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848533
d5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978393
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.33254
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33455
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
MRPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32265
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7724
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19255
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
Neoplasms, Embryonal And Mixed	DisGeNET Gene-Disease Associations	1.0	null
Perturb_3220_KO_C3ar1_ERP024585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.89532
Perturb_5057_OE_Mir344_SRP161512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.9154
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.162
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96064
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47289
CHD-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
Neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27612
chromatin organization	GO Biological Process Annotations 2015	1.0	null
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
GSE206270_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Benign teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42971
reduced	GeneRIF Biological Term Annotations	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_5192_KO_Nanog_SRP116119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.68853
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71108
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836966
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70608
Cyclin B1-CDK1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.979
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95846
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5169
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643669
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00401
Nodal receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01627
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47005
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26141
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92384
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1274
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.308
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17700_KO|KD_Pds5a|Pds5b_SRP365503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47853
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6443
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61228
Perturb_2036_KO_Nrf2_SRP408559	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36506
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44291
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.259
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13335
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_18607_Mut_Chek1_SRP299085	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.28105
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8956
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38921
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57363
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02454
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20597
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
KLF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32199
Chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.439
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0324
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.5
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993256
hsa-miR-181c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12634
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.479
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74055
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43402
JAR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
Pronucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
mRNA_NANOG_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Mature teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57886
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40492
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8369
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
NCI-H650	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76293
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
Tonne-Kalscheuer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
methylated histone binding	GO Molecular Function Annotations 2015	1.0	null
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10017
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1911
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38156
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31342
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5170-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99625
SOX2-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2754
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.936629
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
SOX2-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93859
NCI-H441	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.2043
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06974
LBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36953
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.223
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.986
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.48407
HT-1376	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06816
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.248578
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73636
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70021
Granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.769725
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60662
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7297
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1705
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87173
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.397843
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16347
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487496
NCI-H1734	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Trophoblast stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.908
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1744
hsa-miR-3160-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02752
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60451
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5200-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.94892
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48042
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11785
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81913
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49397
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36916
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915774
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
NCI-H2171	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84485
hsa-miR-181b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
ChIP_NANOG_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165174,GSE165175_0_v_1_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51177
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Amniotic cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.736
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172412
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
IALM	CCLE Cell Line Gene CNV Profiles	1.0	2.43936
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32033
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.994655
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46851
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71887
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.87634
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18957
esBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03237
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
Liver cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47826
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302838
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1532
GSE184133,GSE184137_1_v_9_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8185471-mmc4.xlsx-hESC-DEGs_between_SOX15_KO_hESCs_and_WT_hESCs_cells_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05464
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13725
methylation-dependent protein binding	GO Molecular Function Annotations 2023	1.0	null
negative regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_KLF2_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05433
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30989
Te	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.621
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06768
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894728
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9259
C8orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77473
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.44518
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.39656
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23343
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33569
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
496100292_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01659
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
embryogenesis	GeneRIF Biological Term Annotations	1.0	null
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9685
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	208.84
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCCIT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
maternal	GeneRIF Biological Term Annotations	1.0	null
embryonic cleavage	GO Biological Process Annotations 2015	1.0	null
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050394
negative regulation of dna demethylation	GO Biological Process Annotations 2015	1.0	null
Gonadal mitotic phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41285
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22735
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24526
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
ChIP_KLF5_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19821
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949996
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42474
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28701
gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.577215
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H2029	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
reduced fertility	MPO Gene-Phenotype Associations	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954355
Blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.796
cellular_component	GO Cellular Component Annotations 2015	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232029
maintenance of DNA methylation at imprinted genes	GO Biological Process Annotations 2023	1.0	null
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
retrotransposition	GeneRIF Biological Term Annotations	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885572
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58562
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19913
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745864
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38184
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37284
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64242
Maternal to zygotic transition (MZT)	Reactome Pathways 2024	1.0	null
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91431
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6296
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.49469
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91683
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02184
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60257
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.904
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
Krebs II ascites cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
Germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.232
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31821
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amnion epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
Germ cell cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.29
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8879
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11609
hsa-miR-188-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RCOR3	ChEA Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.56532
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26571
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10834
TE-03 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
PMC6949682__F5	PFOCR Pathway Figure Associations 2023	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40064
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.249
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHRAC	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.836
PMC11103934-mmc2.pdf-10-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
Neoplasms, Germ Cell and Embryonal	CTD Gene-Disease Associations	1.0	2.88009
Dysgerminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.851
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26409
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Trophoblast stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68714
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
ZC3H7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87995
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047576
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30242
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.743313
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_12849_KO_Rnf114_SRP301146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.67245
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2555
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36924
immunodeficiency-centromeric instability-facial anomalies syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
STAT3	ChEA Transcription Factor Targets	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22375
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.102
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
Anterior visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11563
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42776
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34677
tissuespecific	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882118
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837584
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32989
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9312
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8329
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60408
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOX17_01_300	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.74633
Yolk sac cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72522
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46086
Oviductal ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42677
Theca externa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7625
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24108
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85765
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36399
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06814
Embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.607
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978393
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.95
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5687
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04559
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36951
immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144081
Perturb_17333_OE_NANOS1_SRP216951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.28861
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0987
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7839
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53676
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Perturb_12599_KD_Gatad2b_SRP366371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.11949
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7162
GSE98964_1_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NT2/D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
Borderline Personality Disorder	DisGeNET Gene-Disease Associations	1.0	null
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32882
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
46,XY sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29537
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76759
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.769725
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
maternal effect	MGI Mouse Phenotype Associations 2023	1.0	null
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11367
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2981
Perturb_11902_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.90947
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.48873
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98636
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3117
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hiPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836386
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4329
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
NCI-H2066	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
Cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
hsa-miR-3651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77842
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180513
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25791
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042513
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77979
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
KLF4-18264089-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.253
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4667_KO_Setd5_ERP110684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65812
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18129
plastid-encoded plastid RNA polymerase complex B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66027
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77792
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05555
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967998
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
mRNA_SOX2_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Transient neonatal diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.121
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28523
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08454
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.09
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.822757
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Primitive endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.289
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12295
Perturb_9516_Mut_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.71771
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5127
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3201
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20951
Perturb_15712_KD_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79401
ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.905
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11401
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02258
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8163
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03076
Female pronucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.036
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48302
regulation of dna methylation	GO Biological Process Annotations 2015	1.0	null
blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06382
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.555
abnormal dna methylation	MPO Gene-Phenotype Associations	1.0	null
Activin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.28
RAD21	ENCODE Transcription Factor Targets	1.0	null
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6506
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
MAX	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.57994
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33802
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062369
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7148
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05472
nucleus	GO Cellular Component Annotations 2015	1.0	null
mice	GeneRIF Biological Term Annotations	1.0	null
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
adult	GeneRIF Biological Term Annotations	1.0	null
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.1635
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80935
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86058
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1963
negative regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.187333
Perturb_5040_KD_Smarcc1_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2086
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO3_01_267	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.65887
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DU-145	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Cancer, Embryonal And Mixed	DisGeNET Gene-Disease Associations	1.0	null
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70237
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0781
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8319
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56136
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0343
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6771
vitamin c_mus musculus_gpl6246_gse32994	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NANOG-18700969-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.42578
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75981
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28629
vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303919
Testicular germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.40397
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86227
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5564037__F4	PFOCR Pathway Figure Associations 2024	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.45708
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32033
Ovary epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
46,XY sex reversal 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81323
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50507
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83407
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6882
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2083
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29096
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18039
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35209
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53737
HTRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.507
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.028
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.624658
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6738
Perturb_5247_KO_Tfcp2l1_SRP288317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5512
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1919
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07391
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05006
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66024
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5931
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
ISWI-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.8
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66564
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06436
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31145
Yolk sac cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08929
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
IST-MES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163662
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98393
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09165
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51812
mRNA_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4381
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.24576
somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.993249
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71186
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25134
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_19_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70972
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.734323
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germ Cell Cancer	DisGeNET Gene-Disease Associations	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11357
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044816
TSFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38238
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25592
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05357
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9173
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86586
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42594
GSE150215_1_v_2_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.536
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.71596
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.67327
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052904
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092301
CCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56081
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7586
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853916
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06569
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24219
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.8445
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37225
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.652
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8164
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.75403
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68404
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4929
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2094
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59924
81.3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89302
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1786
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96735
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05362
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_RAD21_21589869	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
SOX2-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4028
female pronucleus	GO Cellular Component Annotations 2025	1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
SALL4-18804426-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POU5F1-18700969-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197021
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30461
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1059
GSE214161,GSE214233_0_v_2_zmym2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Activin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48543
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
Mixed germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06792
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01833
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19913
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.850425
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1078
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53118
Teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.664
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4115
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78582
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48223
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.809
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1685
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38145
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15855
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09278
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
Perturb_17410_KO_Kat7_SRP346205	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_5146_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.8352
NANOG-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Teratocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
male pronucleus	GO Cellular Component Annotations 2015	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
seminoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.91052
abnormal female reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0042
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99184
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322414
facilitating	GeneRIF Biological Term Annotations	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0754
Turner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
epiblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0625
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60868
Apolipoprotein B mRNA editing enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
PMC11103934-mmc1.pdf-3-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
KP4	CCLE Cell Line Gene CNV Profiles	1.0	1.77928
BHT-101	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6304
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94216
embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07529
SOX2-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Placenta cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80027
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22574
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47692
biological regulation	GO Biological Process Annotations 2015	1.0	null
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30861
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8996_KO_KMT2C_SRP286164	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.17125
GSE183480,GSE184446_1_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amnion epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
pluripotent	GeneRIF Biological Term Annotations	1.0	null
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33284
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053829
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23699
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.861
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.03794
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15243
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02544
Ovarian surface epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47582
OV7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36135
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6304
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873158
Activin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.249
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5402
regulation of dna metabolic process	GO Biological Process Annotations 2015	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5133
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37792
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55949
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
786-0	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7756
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.513
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-A4SR-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ovarian cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70115
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1963
RPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32931
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
failure of zygotic cell division	MGI Mouse Phenotype Associations 2023	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5823
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76543
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28779
CGR-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82403
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
Human amniotic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5697
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63904
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26435
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44669
ovary	GTEx Tissue Gene Expression Profiles	1.0	2.17226
cell division	GO Biological Process Annotations 2015	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3043
KLF5	ChEA Transcription Factor Targets	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.939805
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62849
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47261
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54183
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54551
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.382
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF5-18264089-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48871
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94744
granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15283
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16545
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5676_KD_Kdm5b_SRP362502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.93064
Autosomal dominant cerebellar ataxia, deafness and narcolepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.44914
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08889
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70618
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56152
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973034
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
reprogramming	GeneRIF Biological Term Annotations	1.0	null
KLF5-18264089-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.692
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050629
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.01811
Perturb_2198_KO_Map3k7_SRP237503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04779
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15045
KLF2-18264089-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069791
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4402
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.806444
regulation of genetic imprinting	GO Biological Process Annotations 2023	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52347
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.365
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
Embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.317
experiments	GeneRIF Biological Term Annotations	1.0	null
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.097
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.913903
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ectoplacental cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07919
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
reduced female fertility	MGI Mouse Phenotype Associations 2023	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8713
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08071
ChIP_POU5F1_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33191
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.02086
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3937
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
germ	GeneRIF Biological Term Annotations	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3877
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.17
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59101
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
epigenetic programing of female pronucleus	GO Biological Process Annotations 2025	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45738
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.45521
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.16556
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5508
NACC1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NL-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Neonatal diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7778
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5682-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77476
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978393
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36712
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.020286
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
Perturb_13203_KO_Stat3_SRP213608	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885572
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45199
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
ES-E14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33432
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
single-organism process	GO Biological Process Annotations 2015	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03755
Perturb_5716_KO_Chaf1b_ERP006640	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Ovarian epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
Embryonal Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
negative regulation of gene expression, epigenetic	GO Biological Process Annotations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73973
Perturb_5213_KO_Terc_SRP156128	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72281
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
45,X/46,XY mixed gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
maintenance	GeneRIF Biological Term Annotations	1.0	null
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81371
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48136
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
Blastocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
TBX3	ChEA Transcription Factor Targets	1.0	null
PMC5564037__F4	PFOCR Pathway Figure Associations 2023	1.0	null
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.749644
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
1HAEo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
stage	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3923	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
stella	GeneRIF Biological Term Annotations	1.0	null
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68379
chromatin modification	GO Biological Process Annotations 2015	1.0	null
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
Blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.922
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.681
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910183
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
female pronucleus	GO Cellular Component Annotations 2015	1.0	null
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1364
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01644
mRNA_ZFP281_18757296	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.332
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68404
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.07575
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00649
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.615
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64147
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19821
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60523
Erythema	DisGeNET Gene-Disease Associations	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8013
REST	ChEA Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43317
ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60945
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903262
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
MG1.19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.224558
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5593
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6408
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
laminin-10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
failure of zygotic cell division	MPO Gene-Phenotype Associations	1.0	null
Primordial germ cell_Ovary_Human	CellMarker Gene-Cell Type Associations	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77994
laminin-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.235
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4327
abnormal preimplantation embryo development	MPO Gene-Phenotype Associations	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.37206
Mixed testicular germ cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71241
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50221
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of DNA demethylation	GO Biological Process Annotations 2023	1.0	null
Germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3188
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21569
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GPAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30707
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73682
NANOG-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_8_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
PRC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.62
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7869
Developmental Biology	Reactome Pathways 2024	1.0	null
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7082
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46856
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17699_KO_Pds5a_SRP365503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25806
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27121
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14008
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67613
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31515
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942981
Beckwith-Wiedemann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7718
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53176
CTCF	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.368
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primordial germ cell_Endoderm_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pluripotent stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.421
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75091
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22603
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
SALL4	ChEA Transcription Factor Targets	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.13449
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.83489
Germ cell_Embryo_Human	CellMarker Gene-Cell Type Associations	1.0	null
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28984
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36692
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09584
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Choriocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894728
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993256
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
Germinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
MPV17L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67019
reduced female fertility	MPO Gene-Phenotype Associations	1.0	null
Trophoblast giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2572
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.739678
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.941355
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4521
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09743
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23731
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
Krebs ascites cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
methylation-dependent protein binding	GO Molecular Function Annotations 2025	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01496
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.58008
Amnion epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
chromatin reprogramming in the zygote	GO Biological Process Annotations 2023	1.0	null
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948184
other phenotype	MPO Gene-Phenotype Associations	1.0	null
Immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.001
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.29368
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90717
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88138
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6972
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50582
KLM1	CCLE Cell Line Gene CNV Profiles	1.0	1.47815
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
Spermatocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRAF_drug inhibition_GSE42872_368_human_A375	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21318
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831991
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
Perturb_6578_KO_Zeb2_SRP066910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23071
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7004
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31524
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NACC1	ChEA Transcription Factor Targets	1.0	null
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.656
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13519
Seminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.33
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.741327
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053467
Adult teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10269
Brain Lower Grade Glioma_LGG_TCGA-WY-A85A-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.37872
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51067
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6122
methylation	GeneRIF Biological Term Annotations	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80017
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5103
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
Extraembryonic tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.423
pronucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72621
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86423
GSE164118,GSE168829_2_v_3_foxp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
hsa-miR-888	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
germinal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04664
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64549
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SWI/SNF superfamily-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.912
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
Ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.744
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2222
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269867
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
Germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.856
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36141
POU5F1	ChEA Transcription Factor Targets	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847367
endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.919061
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06834
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16196
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protection of dna demethylation of female pronucleus	GO Biological Process Annotations 2015	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954355
MIH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49151
Perturb_5161_KO_Trp53_SRP048945	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.985161
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_5036_KD_Smarcc1_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55165
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177832
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.074
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03562
Perturb_5109_OE_Trim66_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.32467
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954355
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21311
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
R1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72092
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
GSE122067_3_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28135
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Migration phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
NCI-H661	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.017
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.18
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860361
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6322
Embryonal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.304
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9615
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.251
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99372
GABPA_01_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	10.0152
Blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.38
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44314
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896765
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
Embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.288
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70638
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16873
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072142
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOX7_01_299	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.37425
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24108
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29228
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
MHHCALL4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72154
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pou5f1_16518401_mesc_lof_mouse_gpl1261_gds1824	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.32985
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35967
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBFB_01_43	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.3147
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2838
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978393
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.604
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40982
targeted	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_SOX2_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868581
LS1034	CCLE Cell Line Gene CNV Profiles	1.0	2.17807
Silver-Russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07765
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062676
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3467
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42399
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92922
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
hESC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24108
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41404
germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12792
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26022
fertilization	GeneRIF Biological Term Annotations	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2215
embryoid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4589
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.05428
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
pronucleus	GO Cellular Component Annotations 2025	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82568
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8802
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36561
abnormal DNA methylation	MGI Mouse Phenotype Associations 2023	1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13123
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.891798
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40092
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92319
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23599
mef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.629101
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17598
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99373
KCTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93172
ChIP_NANOG_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32577
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
Yo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15938
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108703
Spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82867
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
Eb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.251
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Germ Cell Tumor	DisGeNET Gene-Disease Associations	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
Plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.314
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fertility	GeneRIF Biological Term Annotations	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08889
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06436
regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8081
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979281
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41687
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66368
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
embryonic growth arrest	MPO Gene-Phenotype Associations	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151494_1_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06903
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10554
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.214
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08684
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06436
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08663
knockout	GeneRIF Biological Term Annotations	1.0	null
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66523
histone binding	GO Molecular Function Annotations 2015	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0167
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99376
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0281
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.691
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40882
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02798
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesendoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
Perturb_13274_KO_Zbtb24_SRP198760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2349
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.372
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62905
MT-ND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20324
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4618
ETV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34983
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.079702
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3184
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28086
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9192
SEPTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9302
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28909
Brain germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.272
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
GSE184133,GSE184137_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.362
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
oogenesis	GeneRIF Biological Term Annotations	1.0	null
Eht	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
Male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
496100394_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19842
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56408
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15141
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584823
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.356
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49304
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0343
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.122
female	GeneRIF Biological Term Annotations	1.0	null
Visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.159
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6292
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76832
Brain Lower Grade Glioma_LGG_TCGA-CS-6666-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04143
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127075
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97083
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246769
Perturb_5277_KO_Dppa3_SRP362602	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.51996
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.091
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
PMC12768487-NIHMS2129409-supplement-4.xlsx-2D_3D_TFEA_shared-TFEA_for_siSIRT3_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
laminin-11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
POU5F1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
Kidney Chromophobe_KICH_TCGA-KN-8418-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26029
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893938
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49711
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4853-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
Yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7521
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6194
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.965
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.83
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973034
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04367
hsa-miR-548m	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
Perturb_5009_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19785
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
regulation of DNA demethylation	GO Biological Process Annotations 2023	1.0	null
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
NuRD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.673
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837584
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
Perturb_4787_KD_Akap8_SRP075747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
methylated histone binding	GO Molecular Function Annotations 2023	1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0406
EMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87587
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3384
germline	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-610	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Ps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93167
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84428
negative regulation of dna metabolic process	GO Biological Process Annotations 2015	1.0	null
endodermal	GeneRIF Biological Term Annotations	1.0	null
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8321
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38643
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.37717
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81122
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43131
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.07372
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9286
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.663
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9119
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53498
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
originate	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052775
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050642
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55722
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Extravillous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90057
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11291
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8949
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24503
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40121
KLF4	ChEA Transcription Factor Targets	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INA6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52103
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
SK-GT-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
hPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.129
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04286
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.552
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3243
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10822
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.75
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74397
Germ cell benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65572
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16201
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3688
17344918-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05084
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54606
ChIP_SOX2_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19454
NCI-H1781	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
primordial	GeneRIF Biological Term Annotations	1.0	null
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8327
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053956
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2884
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057014
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1831
SOX2-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.46478
PMC6949682__F5	PFOCR Pathway Figure Associations 2024	1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
maternal effect	MPO Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89302
Induced pluripotent stem cell_Undefined_Human	CellMarker Gene-Cell Type Associations	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38887
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.282
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87641
Germ cell_Ovary_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17486
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4544
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6019
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Small luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
ESC/E(Z) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.813
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08219
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8398
PMC4122406-pone.0104158.s010.pdf-22-DLX5_DLX5	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
transcripts	GeneRIF Biological Term Annotations	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993256
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
protein binding	GO Molecular Function Annotations 2015	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6767
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4253
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13842
guanyl-nucleotide exchange factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4502
Germinal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.971
Perturb_15717_OE_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.02005
Perturb_72_KD_DNTM3B_SRP315598	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.82486
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44648
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.838551
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4555
MXI1	ENCODE Transcription Factor Targets	1.0	null
MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11252
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90899
Cumulus cell_Ovarian follicle_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87268
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.56354
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100350_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61522
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.299
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
nucleus	GO Cellular Component Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992987
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
E2F6	ENCODE Transcription Factor Targets	1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1181
IA-LM	COSMIC Cell Line Gene CNV Profiles	1.0	2.22917
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836386
regulation of genetic imprinting	GO Biological Process Annotations 2015	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21351
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37564
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68655
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5102_KD_Ep300_SRP225823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5165
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P12ICHIKAWA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43352
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07391
Embryoid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.277
Cer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
White matter hyperintensities in ischemic stroke	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46961
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3154
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.239
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.905
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88835
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873158
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48108
PMC5783456__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
Epiblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.975
epigenetic	GeneRIF Biological Term Annotations	1.0	null
Nkx-2.5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047029
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2505
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24669
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34255
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.943134
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7582
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643