association dataset threshold value standardized value ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.912232 CRABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00487 M059K CCLE Cell Line Gene CNV Profiles 1.0 1.36368 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.8023 MYC_Activation - 24 hours_GDS2025_726_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE150072,GSE169209_6_v_11_qser1_human RummaGEO Gene Perturbation Signatures -1.0 null TCF3-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.590036 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.993932 marker GeneRIF Biological Term Annotations 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.426872 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.651 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09091 NCIH2227 CCLE Cell Line Gene Expression Profiles 1.0 1.62471 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49456 Amniotic cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.019 JVM2 CCLE Cell Line Gene Expression Profiles 1.0 1.49181 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.850975 nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null 19134196-Figure1 GeneSigDB Published Gene Signatures 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20058 Embryonic stem cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 NT5C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27747 Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79689 GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null no abnormal phenotype detected MGI Mouse Phenotype Associations 2023 1.0 null RPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82686 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35379 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42046 CLCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05397 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.42488 BT483 CCLE Cell Line Gene CNV Profiles -1.0 -1.60473 septostriatal part of the olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40659 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU216 DepMap CRISPR Gene Dependency 1.0 2.40435 TUHR14TKB DepMap CRISPR Gene Dependency 1.0 3.06013 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852058 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.162707 Gustatory areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7232 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28228 Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951 APBB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48187 TE-03 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.039 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07039 H3K9me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VR-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04477 PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0714 SNRPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.91666 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.37378 Germ cell cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.011 SKHEP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.61547 GSE241701_2_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null external male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.273696 SLC30A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01126 CCDC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99633 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937694 DOLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31791 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65289 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975969 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.89 PIGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66611 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42199 SW-1573/S1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.509 Primary somatosensory area, unassigned, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19442 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97786 Epithelioid trophoblastic tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 binding GO Molecular Function Annotations 2015 1.0 null TBC1D4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23705 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00114 JUN ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.11 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05213 TCF3-18467660-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mRNA_SOX2_17515932 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13623 GDF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81594 ZIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2335 ChIP_TCF3_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Nanog_KD_GDS1824_134_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50589 Male pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.769 Invertasome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.136 LCN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02784 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884576 Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EM2 CCLE Cell Line Gene CNV Profiles 1.0 1.95284 Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Germ cell and embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.445 CA46 CCLE Cell Line Gene Expression Profiles 1.0 1.41043 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20383 SGCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38853 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null HOXC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10747 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00544 RPS6KA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96038 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.66219 MDAMB231 CCLE Cell Line Gene CNV Profiles 1.0 1.49408 GSE231648_4_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE216043_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ANAPC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66875 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.50079 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04581 superficial stratum of p2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25694 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.94475 superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0653 SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GCNP_SHH_UP_LATE.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Calcitonin family receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.957 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15655 JHUEM1 DepMap CRISPR Gene Dependency 1.0 2.7838 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11732 OARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03461 Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.914466 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72572 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053756 Taenia tecta, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.55908 Embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.876 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.488 Brain Lower Grade Glioma_LGG_TCGA-DB-A64R-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13259_KO_Pcgf5_SRP115638 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.8012 GSE112760,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.628 Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28726 GSE216043_11_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE224294_4_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null CNDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28503 TP53RK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03689 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4478 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KYSE270 DepMap CRISPR Gene Dependency 1.0 3.3992 Subcortical maternal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.934 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902924 Extravillous trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.125 Meiotic spindle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.637 Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76587 Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0485 GSE145915_0_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5307-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null SOX2-21211035-LN229-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3899 SNU324 CCLE Cell Line Gene CNV Profiles -1.0 -1.55837 FZD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56835 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 NCIH446 DepMap CRISPR Gene Dependency 1.0 3.66584 Perturb_4667_KO_Setd5_ERP110684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.52939 ChIP_POU5F1_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null insulin-responsive compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.205 cisplatin_mus musculus_gpl339_gse6206 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.55888 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85645 GSE216043_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null HAPLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81291 RI1 DepMap CRISPR Gene Dependency 1.0 3.94074 PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 RH18 CCLE Cell Line Gene Expression Profiles -1.0 -1.89969 GSE122101,GSE122103_3_v_1_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null SHSY5Y DepMap CRISPR Gene Dependency 1.0 3.24189 GLI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2562 H3K36me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70874 496100627_TCx_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.6156 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.890233 KLHDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23907 GSE179002_4_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null JHH4 CCLE Cell Line Gene Expression Profiles -1.0 -1.81512 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.7754 ZNF507 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0512 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08568 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85427 GSE165704_0_v_1_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28749 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92825 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056843 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61286 hESC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.932 SCCOHT1 DepMap CRISPR Gene Dependency 1.0 2.2636 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.938391 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.948729 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09013 GSE112760,GSE112767_4_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.27045 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 MSTO211H DepMap CRISPR Gene Dependency 1.0 2.88678 ATOH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19401 GSE211126_1_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9478 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM231 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30029 Germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.268 substantia nigra compacta, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44091 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08568 Interanterodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1409 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.247852 developmental process GO Biological Process Annotations 2015 1.0 null DKC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59476 mRNA_POU5F1_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6U1-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34036 paracentral lobule, anterior part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24044 r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26858 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_POU5F1_20526341 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE107505_1_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mediodorsal nucleus of the thalamus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36677 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052404 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39332 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.18921 superficial stratum of SePal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00301 RAB20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53942 PSMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91674 hsa-miR-4701-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 RPMI8226 DepMap CRISPR Gene Dependency 1.0 3.48871 Syncytiotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.455 PTPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56533 TCF3-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CGB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16155 RPS19BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76854 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2144 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.79309 TMEM167A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15243 Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32503 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.54952 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BICR6 DepMap CRISPR Gene Dependency 1.0 3.56392 Amnion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.342 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8403 TFDP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1948 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040419 RAJI COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 Neural plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.194 Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.68 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852058 H3K36me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null differentially GeneRIF Biological Term Annotations 1.0 null mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49796 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041571 G59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25268 DDX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5935 nasopharynx HPA Tissue Protein Expression Profiles 1.0 2.75207 SPI1 ChEA Transcription Factor Targets 1.0 null Perturb_14940_OE_hPRDM15_SRP182668 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.40873 PDCD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36824 Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32355 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRISPLD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1036 Perturb_5231_KO_Kmt5c_SRP194976 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15211 GSE129389_0_v_6_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null GPATCH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37549 rna binding GO Molecular Function Annotations 2015 1.0 null CEP135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8198 SLR24 DepMap CRISPR Gene Dependency 1.0 2.83362 Perturb_3046_KO_Smarcd3_SRP044338 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.79568 LU99 CCLE Cell Line Gene CNV Profiles 1.0 1.37216 Gestational trophoblastic neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.48 496100493_TCx_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.58523 Perturb_14939_OE_hPRDM15_SRP182668 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.71936 Blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.084 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02486 JUN-21703547-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NOMO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.34877 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22212 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tooth ankylosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 Perturb_5010_KO_Sall4_ERP122174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.8414 Intercalated nucleus of amygdala Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885422 Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.12161 germ cell and embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.416521 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7512 Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G5-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TJP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95041 496100297_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.9491 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30981 PMC11103934-mmc2.pdf-10-SALL4_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null KKU100 DepMap CRISPR Gene Dependency 1.0 4.13335 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922972 HSD11B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4324 WDR18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78402 IRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03573 GSE206870,GSE206872_4_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null follicle-stimulating hormone complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.721 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961588 m2 part of substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32878 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852058 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83007 HCC2450 DepMap CRISPR Gene Dependency 1.0 2.34638 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2404 KYSE410 CCLE Cell Line Gene CNV Profiles -1.0 -1.57521 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837263 Severe congenital neutropenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.15413 H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UBE2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01074 cochlear nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.833165 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37918 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.75304 Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.3828 Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A549 CCLE Cell Line Gene Expression Profiles 1.0 1.79578 NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.398 GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCAPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00736 specifically GeneRIF Biological Term Annotations 1.0 null ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.7148 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21465 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24879 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Follicular fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.743 ARF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49109 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.162249 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08089 GSE216043_11_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null KHM1B CCLE Cell Line Gene Expression Profiles 1.0 1.43522 MZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.897194 GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MEX3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56049 mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.69849 normal phenotype MPO Gene-Phenotype Associations 1.0 null Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -1.71533 HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.837378 Human amniotic epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.872 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25268 CSNK2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86025 MCEE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41933 GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hoxc13_OE_GDS1890_174_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_5162_KD_Mbd2_SRP051519 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.43491 single-organism developmental process GO Biological Process Annotations 2015 1.0 null inner CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.841103 SLVL DepMap CRISPR Gene Dependency 1.0 3.81532 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.474 JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.76188 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Islands of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18617 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_13277_KO_Bach1_SRP238575 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blastocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.723631 496100329_FWM_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43021 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.7389 clone81 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.566 RERFGC1B CCLE Cell Line Gene Expression Profiles 1.0 3.40743 PDE10A_KO_GSE40377_581_mouse_Striatum and hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HSC5 DepMap CRISPR Gene Dependency 1.0 2.32085 WM88 DepMap CRISPR Gene Dependency 1.0 2.845 ARMCX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28233 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46905 Amylin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.742 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.978279 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919872 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.973991 PMC9213552-41467_2022_30858_MOESM6_ESM.xlsx-Hu-FGF4_and_NANOG-List_of_the_genes_correlated_with_both_FGF4_and_NANOG_expression_in_ICMd_cells_NANOG Rummagene Transcription Factor Associations 2026 1.0 null ZDHHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5661 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43321 Perturb_12596_KD_Chd4_SRP366371 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.25608 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958645 prepuce TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.432225 Uterine wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.773 pluripotent GeneRIF Biological Term Annotations 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00582 Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5421 Hepatitis, Autoimmune_Hepatic Tissue_GSE867 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.38819 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-314-FOXP4_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_13257_KO_Pcgf3_SRP115638 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.4467 CASC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99138 Perturb_13215_KD_Ptbp1/Ptbp2_SRP061311 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.33239 Trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.985 Node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.51 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09862 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39511 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25268 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29373 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.62752 SS18L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26958 Perturb_4992_KO_Mettl5_SRP268611 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.351 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, mouth, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67492 Trophoblast stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.823 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.50313 ERH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00485 RTEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54546 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU5F1-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_305_KD_Pabpn1_SRP318863 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 496100663_TCx_no dementia_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.20375 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null VAESBJ DepMap CRISPR Gene Dependency 1.0 2.04933 SKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE206270_2_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null TIMM29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.479 RPS24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02775 iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.82847 GSE176008_8_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE216043_11_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE211286_4_v_5_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-941 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Perturb_15719_KD_Ctcf_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_4522_KO_Mapk3_SRP281895 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.57141 Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JURLMK1 DepMap CRISPR Gene Dependency 1.0 2.27535 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.1457 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55775 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JC-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonadal mitotic phase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null 496100495_FWM_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.75112 ASH2L ChEA Transcription Factor Targets 1.0 null multicellular organismal development GO Biological Process Annotations 2015 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052752 smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060784 Adenocarcinoma of lung_Lung Tissue_GSE1037 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.44545 osteogenic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.107115 Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01474 nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.984597 thyroid GTEx Tissue Gene Expression Profiles 1.0 1.20615 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52765 HS870T CCLE Cell Line Gene Expression Profiles 1.0 1.79967 ChIP_SOX2_19030024 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null UT7 CCLE Cell Line Gene Expression Profiles 1.0 1.47812 ChIP_ASH2L_23239880 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE120336_0_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-4772-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 S100A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34321 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.19447 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.38034 NP5 DepMap CRISPR Gene Dependency 1.0 3.28785 CYP2S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3585 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9091 UBR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09723 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20283 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17683608-TableS5 GeneSigDB Published Gene Signatures 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961588 TCF3 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.555274 Blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.324 Amnion epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.614 GSE199255,GSE199356_4_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MYC-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSS DepMap CRISPR Gene Dependency 1.0 2.07576 GSE130081,GSE130082_5_v_10_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lobule III, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06775 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231648_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40782 Sto TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.957 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04297 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.90716 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_KLF4_19030024 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.663149 hsa-miR-3652 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00514 NFU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46451 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null VPS33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9426 HEC265 DepMap CRISPR Gene Dependency 1.0 3.08187 cerebellum HPA Tissue Protein Expression Profiles -1.0 -1.0384 mRNA binding GO Molecular Function Annotations 2023 1.0 null Cyclin B1-CDK1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.949 Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3198 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968193 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98244 496100490_HIP_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12206 FRMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24902 Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10629 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49381 HMGA2_KO_GDS5048_26_mouse_embryonic lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE184133,GSE184137_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08196 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21172 EHMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37719 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50022 Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null myometrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.241438 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Embryonal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.892 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950488 Perturb_4945_KO_Rybp/Yaf2/Prc1_SRP247114 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.8459 CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60185 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15572 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.34542 hsa-miR-4446-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 prerubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07318 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.09474 SHQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54716 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.919028 EP300 ENCODE Transcription Factor Targets 1.0 null Perturb_5352_KO_Dux_SRP201141 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.4034 KNS42 CCLE Cell Line Gene CNV Profiles 1.0 1.57016 BFTC905 DepMap CRISPR Gene Dependency 1.0 2.75283 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68703 KMRC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.4889 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.991014 mesenchymal stromal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451428 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.8061 SCC4 DepMap CRISPR Gene Dependency 1.0 2.13452 centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30502 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_5225_KO_Mettl3_SRP184527 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.2147 SH4 CCLE Cell Line Gene Expression Profiles -1.0 -2.06498 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3343-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0825 Extraembryonic tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.732 molecular layer of S Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0488 Primary somatosensory area, lower limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35076 TECPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15944 CENPV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72294 Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30741 Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.555 TMEM175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92331 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.830291 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.864333 periventricular stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21871 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33325 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33632 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.987228 C3orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51045 Epiblast cell_Embryo_Human CellMarker Gene-Cell Type Associations 1.0 null upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3406 IRS2_KO_GDS1219_304_mouse_brown preadipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K36me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2066 CCLE Cell Line Gene Expression Profiles 1.0 1.36747 ZNF384 ENCODE Transcription Factor Targets 1.0 null liver HPA Tissue Protein Expression Profiles -1.0 -1.0384 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3105 Perturb_12846_KO_Setd1b_SRP081141 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 M140325 DepMap CRISPR Gene Dependency 1.0 3.68763 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.0384 superficial stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11624 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0517 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045253 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.37214 DDX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09039 embryonic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.3427 CDC27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72591 layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13626 CLCN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44025 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12724 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.398 NCIH23 DepMap CRISPR Gene Dependency 1.0 3.20147 NUP214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38092 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.35587 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38868 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06783 cytoplasm GO Cellular Component Annotations 2015 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.762811 GSE153137,GSE153140_2_v_1_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE198165,GSE198166_5_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA binding GO Molecular Function Annotations 2025 1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15568 Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null EWS502 CCLE Cell Line Gene Expression Profiles -1.0 -2.13423 Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3729 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.37949 Perturb_5057_OE_Mir344_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.9091 chondrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360036 POU5F1 ChEA Transcription Factor Targets 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975969 beta-TC6 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.604 FBXO17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66376 hsa-miR-4755-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE205976,GSE205978_2_v_5_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null 496100410_TCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04956 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.60149 GSE199255,GSE199356_3_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.573 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 RNF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3-18467660-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adipose-derived stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.925051 layer 2 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34826 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DB-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63774 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90397 GSE206870,GSE206872_3_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966835 MESSA CCLE Cell Line Gene CNV Profiles -1.0 -1.77865 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858366 Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62846 UPCISCC200 DepMap CRISPR Gene Dependency 1.0 2.59189 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8851 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39572 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94249 substantia innominata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867217 hsa-miR-4468 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PCGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15075 SOX2 ChEA Transcription Factor Targets 1.0 null H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5896 B16-F1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.552 Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neural ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.122 DNAJC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37215 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7584-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.315135 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.165655 Fhm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71846 Perturb_5018_KD_Dppa2/Dppa4_SRP187465 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.86597 ACBD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03864 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.02049 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD54B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39053 GSE112761,GSE112767_2_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33706 RCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44917 external globus pallidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11464 NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE179002_2_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11103934-mmc1.pdf-3-SALL4_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.46996 PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX Rummagene Transcription Factor Associations 2026 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86288 outer SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884394 ACKR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31968 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.6906 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5339_KO_Tnfaip2_SRP256539 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41478 DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.987681 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056779 CAPZA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37778 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE84922,GSE84924_0_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5322-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUBB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11776 COLO-679 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0037 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3766 primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.218398 hsa-miR-522 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 LRF MotifMap Predicted Transcription Factor Targets 1.0 null Nso TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.954 APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.01556 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.7604 PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_2_AR Rummagene Transcription Factor Associations 2026 1.0 null Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10532 r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.61915 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.80098 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2789 RAB3A_Mutation - D77G point mutation_GDS2482_704_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE112760,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX19A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0046 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41179 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052355 blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.391176 GSE234340_4_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NB5 DepMap CRISPR Gene Dependency 1.0 2.11532 Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF4G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02295 GATA2_01_61 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.60962 Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975025 GABARAPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14968 ADGRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64942 Primary somatosensory area, mouth, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76452 KP2 DepMap CRISPR Gene Dependency 1.0 3.94512 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72446 r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54265 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09641 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.57575 NCIH292 DepMap CRISPR Gene Dependency 1.0 2.51308 KLRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86125 Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172458_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null RNA binding GO Molecular Function Annotations 2023 1.0 null CAOV3 DepMap CRISPR Gene Dependency 1.0 2.71665 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22407 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17182 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.87201 Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24865 white adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214954 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05213 Perturb_4535_KO_Mll3/Mll4_SRP064855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.4683 SPI1-20176806-THIOMACROPHAGE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE169155_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09987 CCE cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.707 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.76595 PTCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02981 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.941428 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04598 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70953 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55775 POU5F1-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09719 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decitabine_homo sapiens_gpl570_gse30985 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perivitelline space COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.943 JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.28267 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837263 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.67337 Perturb_4508_KO_Nkx3.1_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Germinal disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.387 periventricular stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84361 GSE120336_1_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.693 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43456 intracellular part GO Cellular Component Annotations 2015 1.0 null Perturb_13294_KO_Stk40_SRP182898 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.10209 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.46203 Perturb_5164_KD_Aff3_SRP051521 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 maturity-onset diabetes of the young type 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.248 ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.1739 Cytotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.394 Ooplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.51 COLO775 CCLE Cell Line Gene CNV Profiles 1.0 1.80097 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.72673 PECAPJ34CLONEC12 DepMap CRISPR Gene Dependency 1.0 2.88472 NANOG-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.09145 HT1376 CCLE Cell Line Gene Expression Profiles -1.0 -2.32063 Embryonic fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.808 C12orf43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4751 NAPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3671 RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 KRCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63851 Taenia tecta, ventral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09554 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15568 biological_process GO Biological Process Annotations 2015 1.0 null ASH2L-23239880-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null TK COSMIC Cell Line Gene Mutation Profiles 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852817 embryonal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.784345 POU5F1-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE189683_3_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11431 Primary somatosensory area, nose, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52037 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67051 H3K9me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null G402 DepMap CRISPR Gene Dependency 1.0 2.38231 Ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.828 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40957 GSE205976,GSE205978_3_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE112860_3_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1689 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0653 PPIE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18375 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37068 GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE216043_11_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6047 HCC202 CCLE Cell Line Gene CNV Profiles -1.0 -2.75646 PFKFB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61427 lung BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.840524 superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24865 nicotine_rattus norvegicus_gpl2896_gse13311 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE231648_1_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6003 SIAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47984 DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85424 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4_KO_Pabpn1l_SRP226170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.23102 Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03114 cell part GO Cellular Component Annotations 2015 1.0 null periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11953 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.95571 PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58438 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.999721 d5 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.18 Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-CoV MA15_Day2_None_GSE49263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.1512 Perturb_13790_KO_Zeb2_SRP066910 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTNNBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30021 mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17182 NZOV9 DepMap CRISPR Gene Dependency 1.0 4.19279 GSE205976,GSE205978_2_v_4_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4828-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25248 GSE133691_2_v_0_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Mesendoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.016 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15919 Perturb_14412_KO_Cnot6/Cnot6L_SRP285826 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.60908 Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE184133,GSE184137_1_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null LOXIMVI CCLE Cell Line Gene Expression Profiles 1.0 1.45147 spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33156 Perturb_5039_KD_Smarca4_SRP221174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.823 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911142 PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.38868 RPAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97547 Perturb_4275_KO_Smchd1_SRP134966 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.30673 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47194 SNU668 DepMap CRISPR Gene Dependency 1.0 2.06711 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0964 embryoid body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.962903 GSE142684_2_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.9536 PALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.262 HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 2.27552 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22797 bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054986 pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24865 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79349 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55216 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37768 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70997 hsa-miR-588 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Perturb_5289_KD_Rpl10a_SRP064202 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.34294 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8851 Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06645 spleen HPA Tissue Protein Expression Profiles -1.0 -1.0384 Somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.128 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Anterior visceral endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.908 SNU13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8138 NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MG1.19 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.376 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6094 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TP-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81762 Yolk sac cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.546 NOMO1 DepMap CRISPR Gene Dependency 1.0 3.80876 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.631166 PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-TFAP2C_TFAP2C Rummagene Transcription Factor Associations 2026 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.475034 Perturb_16117_KO_Mfn1_SRP189355 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.83974 Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975025 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27024 Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2831 GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.9884 Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null b12 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.544 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2228 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34207 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15122 EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4289_KO_Klf5_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 HARA CCLE Cell Line Gene Expression Profiles 1.0 1.72404 496100521_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16118 MERO41 DepMap CRISPR Gene Dependency 1.0 3.47425 Visceral endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.438 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RBMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.31661 MYC_Activation - 21 days_GDS2025_727_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Annulate lamellae COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.516 SBC5 CCLE Cell Line Gene CNV Profiles 1.0 1.58003 CHD1 ENCODE Transcription Factor Targets 1.0 null SKLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.3801 ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2228 ARRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57688 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.20494 REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.1651 ChIP_TCF3_18467660 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Midline group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41884 GSE186660_2_v_1_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52078 T3M10 CCLE Cell Line Gene CNV Profiles -1.0 -1.38028 NOC2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10459 GSE186654_1_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.4221 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.6875 GSE206870,GSE206872_4_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CISH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75015 seminal vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350001 GSE216043_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TMEM63A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42162 SLC18B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06056 inner CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21632 Lobule III, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1513 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.72834 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040462 H9 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.635 HL60 CCLE Cell Line Gene Expression Profiles 1.0 1.83594 PMC7672319-mmc2.xlsx-Stemness_MSigDB62sel_gmx-KORKOLA_CORRELATED_WITH_POU5F1_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null Activin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.96 IALM CCLE Cell Line Gene CNV Profiles 1.0 1.48981 CYTH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43841 sublayer 6a of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5311 MAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79795 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07606 SG231 DepMap CRISPR Gene Dependency 1.0 2.13451 A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.62553 GSE99687_0_v_1_smad5_human RummaGEO Gene Perturbation Signatures -1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040378 GSE120413,GSE120447_0_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.457214 Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13505 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.986939 GSE85723,GSE85833_1_v_0_huwe1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HNRNPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54526 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GSE129389_0_v_3_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8288 GSE122101,GSE122103_0_v_1_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null XRCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15492 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46766 Mature teratoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.396 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null AUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37015 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1797 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.399492 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE112760,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HES6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18072 MCC13 DepMap CRISPR Gene Dependency 1.0 3.70854 ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7508 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886233 Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5007 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.15639 SALL4-18804426_ESC-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.034 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4432 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.439 Acute Myeloid Leukemia_LAML_TCGA-AB-2880-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null INA6 DepMap CRISPR Gene Dependency 1.0 3.54545 regulation of gene expression GO Biological Process Annotations 2025 1.0 null substantia innominata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24746 periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4507 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.1348 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null RAD51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93168 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9961 Perturb_4819_KO_Apex1_SRP193096 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.41211 SRSF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53493 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.901573 Perturb_18605_KO_Pabpn1l_ERP127567 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.978806 Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MERO14 DepMap CRISPR Gene Dependency 1.0 2.69872 GSE150072,GSE169209_4_v_10_qser1_human RummaGEO Gene Perturbation Signatures 1.0 null UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.027 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34036 MMAC DepMap CRISPR Gene Dependency 1.0 2.62788 OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 1.81374 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04862 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.58342 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.881637 PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.860896 GSE205976,GSE205978_1_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures -1.0 null IGF2BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66289 PHF23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59088 ABCC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06546 Perturb_4575_OE_Haspin_SRP271373 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.48327 GTF2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60456 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38885 Perturb_4291_KO_Farp1_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 ANXA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06169 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28863 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.398 Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96774 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46628 GSE120413,GSE120447_0_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79689 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.56407 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15028 ATXN7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.91451 DU145 CCLE Cell Line Gene Expression Profiles -1.0 -1.59633 Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE124375_10_v_9_chd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21485 ST486 DepMap CRISPR Gene Dependency 1.0 2.31296 TRAIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46739 C18orf21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0916 ovary GTEx Tissue Gene Expression Profiles 1.0 1.70636 SLC1A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3349 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852058 GSE226316_0_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.32046 LAMA84 CCLE Cell Line Gene CNV Profiles 1.0 1.39451 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.88219 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.889802 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.95053 fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.537416 ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.5367 Neuroepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.855 RBPMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66329 r8 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47791 C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39437 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.5227 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5056_OE_MERVL_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE84922,GSE84924_4_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null IFFO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40232 e3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.118 KLHL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70287 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16752 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lobule III Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10521 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MED17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41704 CCDC92B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49626 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44688 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04357 Trophoblastic neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.511 BLOC1S3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12268 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16314 KLF4 ChEA Transcription Factor Targets 1.0 null 496100321_HIP_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.81927 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE112765,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMGA2_KO_GSE55340_21_mouse_lung (E18.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37768 ANKRD13C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71904 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.6199 pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33518 GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE112761,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112763,GSE112767_2_v_5_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Gigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12365 trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.095445 ChIP_TCF3_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null GSE199255,GSE199356_4_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null PYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3161 stromal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144784 GABPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22209 blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.49844 MYC-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE169713,GSE169715_1_v_2_tert_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF501 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21016 T84 CCLE Cell Line Gene Expression Profiles 1.0 1.46173 GSE220813_0_v_1_zfp750_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100372_HIP_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5802 TMEM186 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58424 Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73559 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05529 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE194268_2_v_0_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.698864 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04125 GSE188870,GSE188871_4_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100625_FWM_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65481 TTLL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13879 RPS27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03212 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03022 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88782 Perturb_13242_OE_Med24_SRP201000 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.25727 used GeneRIF Biological Term Annotations 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04535 Perturb_4523_KO_Dpf2_ERP105019 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.68227 HDQP1 CCLE Cell Line Gene CNV Profiles 1.0 1.51042 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27178 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.910243 Primary motor area, Layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83325 Blastocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.397 WDR36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8381 PANC0504 DepMap CRISPR Gene Dependency 1.0 2.32086 HOXA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44158 LSM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84353 PCM6 CCLE Cell Line Gene CNV Profiles -1.0 -1.87911 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S0-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46203 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4730-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 2.12573 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72507 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 15856041-FileS1 GeneSigDB Published Gene Signatures 1.0 null MCTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33438 GSE144838_4_v_8_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null 22RV1 CCLE Cell Line Gene Expression Profiles 1.0 2.65494 GSE171837_3_v_1_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76587 cingulate gyrus, retrosplenial part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913689 NEF cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.59 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67277 brown adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213471 GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CEBPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.76252 KLF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.3687 GSE103297_1_v_0_glis3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.84454 RPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68985 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04229 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TUBGCP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10734 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27024 Seminoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.818 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.00845 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.6851 Agranular insular area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19975 r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17651 Perturb_4509_KO_Tbc1d4_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null HUT102 CCLE Cell Line Gene Expression Profiles 1.0 1.85415 MYC ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138001_0_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null CDC73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44935 ASPC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2343 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null USP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05165 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76587 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17651 Pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.194 TYKNU CCLE Cell Line Gene CNV Profiles -1.0 -2.27195 SW756 DepMap CRISPR Gene Dependency 1.0 2.23789 Perturb_9719_OE_Wt1_SRP126738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.69861 GSE145215_0_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null GPAA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3773 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21845 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.82963 hsa-miR-4720-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CHLA15 DepMap CRISPR Gene Dependency 1.0 2.70522 Brain Lower Grade Glioma_LGG_TCGA-R8-A6YH-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAJI CCLE Cell Line Gene CNV Profiles 1.0 2.89984 CAOV4 CCLE Cell Line Gene CNV Profiles -1.0 -1.66625 GSE112762,GSE112767_2_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null USP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73945 GSE122215,GSE122217_0_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46203 GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null trophectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.49844 Primary somatosensory area, unassigned, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32278 embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.750457 Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.644 Melc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.847 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07726 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15522 ATP5PB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1026 ZC3H8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02349 r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27892 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21262 PTPRU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09595 FMR1_KD_GDS4759_333_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE138818_1_v_3_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.738442 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XG-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 697 DepMap CRISPR Gene Dependency 1.0 2.8908 ADISSP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21135 SKNMC CCLE Cell Line Gene Expression Profiles 1.0 1.50824 multicellular organismal process GO Biological Process Annotations 2015 1.0 null 496100406_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11272 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2911 TCF3-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8416 Amniocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.596 NRSN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1338 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247719 MSANTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89872 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6U8-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42022 Perturb_4944_KO_Rybp/Yaf2/Prc1_SRP247114 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16752 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44688 Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.939802 KASUMI6 CCLE Cell Line Gene Expression Profiles -1.0 -1.73722 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93505 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of gene expression GO Biological Process Annotations 2023 1.0 null nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12817 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21172 adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.260945 GSE112760,GSE112767_2_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null NANOG ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null i10 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.796 COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935395 K Homology domain InterPro Predicted Protein Domain Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-216b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34036 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.653 NDUFA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5554 Perturb_15717_OE_Ctcf_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.094 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 TEAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21405 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE182770,GSE182784_0_v_1_chd2_human RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null External cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09512 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68332 GSE98755,GSE98756_1_v_0_fbxl19_mouse RummaGEO Gene Perturbation Signatures -1.0 null mhc class i protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.273734 KLF15_Deficiency_GDS2687_648_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25268 16705683-table3 GeneSigDB Published Gene Signatures 1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27599 PITHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15012 KASUMI2 CCLE Cell Line Gene CNV Profiles -1.0 -1.60951 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.22465 SH4 CCLE Cell Line Gene CNV Profiles -1.0 -2.11693 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-O9-A75Z-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EXOC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62063 Embryoid body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.008 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.84091 p2 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09927 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852817 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.42902 Embryonic stem cell_Embryoid body_Human CellMarker Gene-Cell Type Associations 1.0 null Te TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.767 MRPL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90395 GSE66931,GSE73382_1_v_0_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null red nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.82993 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903756 MRPL49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16078 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966071 cisplatin_mus musculus_gpl339_gds3099 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null GSE113817_0_v_1_bach1_human RummaGEO Gene Perturbation Signatures -1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 penis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33046 regulation of macromolecule metabolic process GO Biological Process Annotations 2023 1.0 null PPP3CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14517 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21507 layer 6 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08775 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98198 germ cell cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.956859 Perturb_13797_KO_Phc1_SRP096055 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 FASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84893 KLF4-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null fat pad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217139 Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.3155 COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -1.80255 menadione_mus musculus_gpl1261_gse23725 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32217 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0536 GSE108675_3_v_0_slc1a4_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00061 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07917 Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.198823 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1906 Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13306 HEC1B DepMap CRISPR Gene Dependency 1.0 2.56544 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2015 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49755 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12459 hTERT-HSC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.005 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laminin-10 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.194 GSE196671_6_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null SLC17A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04499 mhc protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.128634 Ec TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.911 GSE98755,GSE98756_3_v_0_fbxl19_mouse RummaGEO Gene Perturbation Signatures -1.0 null COX5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13913 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907747 H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158285_0_v_1_ddx5_mouse RummaGEO Gene Perturbation Signatures -1.0 null icSARA deltaORF6_7Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.92257 superficial stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08111 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99523 Primary somatosensory area, mouth Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28684 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null KNS42 DepMap CRISPR Gene Dependency 1.0 2.5632 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null RH30 CCLE Cell Line Gene CNV Profiles 1.0 2.6528 GCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16035 hsa-miR-4430 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826122 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04353 ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null RNF220 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57733 Perturb_5669_KD_Yy1_SRP281855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.4911 ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60257 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.84925 layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.97757 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4618 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02297 PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA Rummagene Transcription Factor Associations 2026 1.0 null Seminoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.303 bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3014 SMSCTR DepMap CRISPR Gene Dependency 1.0 2.1926 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74248 Adrenomedullin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.787 PITPNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91694 hsa-miR-1251 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS454 CCLE Cell Line Gene Expression Profiles 1.0 2.31408 ES2 CCLE Cell Line Gene Expression Profiles 1.0 1.45514 PTRH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68172 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21871 navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.52411 MEF2A_KD_GDS4759_340_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045373 Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49858 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26064 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17588 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE241036_0_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null 15256440-tableS1 GeneSigDB Published Gene Signatures 1.0 null EIF3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34279 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.627 T3M5 DepMap CRISPR Gene Dependency 1.0 2.01976 SALL4 ChEA Transcription Factor Targets 1.0 null cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null GSE216043_10_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null cartilage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242672 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null Primary somatosensory area, nose, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23144 Activin A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.813 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1082 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.744627 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.227186 LCLC97TM1 DepMap CRISPR Gene Dependency 1.0 3.48645 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.917588 EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.8403 MECP2_KD_GDS4759_334_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42839 Polar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.249 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.65 MRPS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86335 RAB22A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60458 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE179002_2_v_6_caprin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48151 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.09005 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.349 Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Epi TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.468 GSE149264,GSE149267_4_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null REPIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09478 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15849 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HK2 CCLE Cell Line Gene Expression Profiles -1.0 -1.71573 pluripotency GeneRIF Biological Term Annotations 1.0 null embryonic germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.65107 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.31922 HS3ST3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1913 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961588 B3GNT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20384 cellular_component GO Cellular Component Annotations 2015 1.0 null Endodermal sinus tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 B-16 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.671 CNOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38262 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9669 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.59595 SHISA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07408 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.523982 GSE231648_0_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04284 NCIH358 DepMap CRISPR Gene Dependency 1.0 2.13567 Perturb_5005_OE_Mnx1_ERP140947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Perturb_6592_KO_Dicer_SRP200256 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TTPAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70096 Presubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04315 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03275 163 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.093 Butyrates CTD Gene-Chemical Interactions 1.0 null hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -1.0384 GSE206270_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE162739_6_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.745172 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08581 D458 DepMap CRISPR Gene Dependency 1.0 3.18586 mantle zone of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14393 HS706T CCLE Cell Line Gene Expression Profiles 1.0 1.55357 Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17337 TCF3-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55053 r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97694 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PTEN_KD_GDS4759_337_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE120336_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2777-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.163172 Amnion epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.592 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975969 stem GeneRIF Biological Term Annotations 1.0 null periventricular stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21522 CLIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00898 p1 part of the substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48059 GSE216043_3_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18658 single-organism process GO Biological Process Annotations 2015 1.0 null p2 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38147 Inhibin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.697 NKX6-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02165 superficial stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40659 GSE130081,GSE130082_0_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BCL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24755 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040614 esophagus HPA Tissue Protein Expression Profiles -1.0 -1.0384 no abnormal phenotype detected MPO Gene-Phenotype Associations 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23961 Primitive endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.071 SLC29A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52274 SEPTIN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01642 RERFGC1B CCLE Cell Line Gene CNV Profiles 1.0 1.73824 Adenocarcinoma of lung_Lung Tissue_GSE11969 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.82139 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.443 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04752 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4676 lymph node HPA Tissue Protein Expression Profiles -1.0 -1.0384 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MORCPR CCLE Cell Line Gene CNV Profiles -1.0 -2.73407 Perturb_5017_KD_Dppa2_SRP187465 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.3007 Perturb_4290_KO_Clybl_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Embryonic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.208 HS739T CCLE Cell Line Gene Expression Profiles -1.0 -2.69876 ESS1 DepMap CRISPR Gene Dependency 1.0 2.22695 Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61286 SOX2-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null UTP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90841 TTC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29044 Nkx-2.5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.126 mRNA_POU5F1_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146894_3_v_8_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null MDAMB435S CCLE Cell Line Gene CNV Profiles 1.0 2.08026 vitamin c_mus musculus_gpl6246_gse19378 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RNF2 ENCODE Transcription Factor Targets 1.0 null Amylin receptor complex 2 COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.032 Perturb_13170_KD_Ncor1_SRP060657 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.26696 MITF_01_25 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60244 Perturb_4506_KO_Clybl_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09577 ChIP_SALL4_18804426 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null adipocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224645 Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paragigantocellular reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43774 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KD DepMap CRISPR Gene Dependency 1.0 3.83661 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 appendix HPA Tissue Protein Expression Profiles -1.0 -1.0384 Endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.994 GSE216043_11_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TOLEDO CCLE Cell Line Gene CNV Profiles -1.0 -1.98789 647V CCLE Cell Line Gene Expression Profiles -1.0 -1.59332 Embryonic germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.685 GSE241701_4_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Germinal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.478 PLAGL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.7698 midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49735 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4577_OE_Haspin_SRP271373 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.22741 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93505 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17588 ALDOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53639 ARHGEF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79003 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6415 GSE179002_3_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043272 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.190839 periosteum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.10355 Germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.092 Ovarian cumulus cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.201 MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.46996 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15889 SRY ChEA Transcription Factor Targets 1.0 null GSE231648_1_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26999 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13365 Perturb_9515_KO_Sall4_ERP111723 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.08139 menadione_mus musculus_gpl1261_gds4171 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44747 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49967 emx2_20962046_e10dot5_urogenital_epithelium_lof_mouse_gpl1261_gds3173 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.661288 Perturb_4292_KO_Nkx3.1_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 WA-01 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.155513 RPS29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11552 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49503 GSE224556,GSE224557_8_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null Teratocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.35 NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 2.31051 GSE196671_5_v_0_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.82584 Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64335 IL11RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.576 MHHCALL3 CCLE Cell Line Gene CNV Profiles -1.0 -1.70484 Epiblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.391 Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04341 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11953 Hypoglossal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17011 Perturb_4507_KO_Farp1_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17237 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92825 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33444 mRNA_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.847291 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP1_01_208 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.47971 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.0384 C4orf48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38859 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, mouth, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4678 DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 1.89527 Perturb_4836_KO_Chd8_SRP306703 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.25302 NCIH2023 CCLE Cell Line Gene Expression Profiles -1.0 -2.9487 Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.519 SLC50A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70242 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.837977 inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08506 hsa-miR-3929 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE199874_2_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SALL4-18804426-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6742 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164508_1_v_0_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTDK-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.554 SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50853 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52656 Primary somatosensory area, upper limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37094 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961588 GSE198165,GSE198166_5_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null LUDLU1 CCLE Cell Line Gene Expression Profiles 1.0 1.40178 LAMTOR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16854 15856041-Figure1 GeneSigDB Published Gene Signatures 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.45567 GSE216043_11_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null SW1990 DepMap CRISPR Gene Dependency 1.0 2.0798 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0685 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.643089 SPECC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21209 LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33534 GSE74251_0_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3036 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 GSE135400_2_v_0_kdm1b_mouse RummaGEO Gene Perturbation Signatures 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43851 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prostate HPA Tissue Protein Expression Profiles -1.0 -1.0384 SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55775 Germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.445 GSE213410_0_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.0338 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6905 TE14 CCLE Cell Line Gene Expression Profiles -1.0 -1.48302 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r9 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64796 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.37399 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5094 NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null CKAP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28762 SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18198 nucleic acid binding GO Molecular Function Annotations 2015 1.0 null MDAMB435S DepMap CRISPR Gene Dependency 1.0 2.96144 UACC257 CCLE Cell Line Gene CNV Profiles 1.0 1.67347 Connecting stalk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5259_KD_Ubn1_SRP323703 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.59246 Perturb_5288_KD_Rpl10a_SRP064202 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.86587 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.989086 POU5F1-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.52927 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52015 Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU886 CCLE Cell Line Gene Expression Profiles -1.0 -1.76112 KM12 CCLE Cell Line Gene Expression Profiles 1.0 2.15406 Embryonic carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.358 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040335 GSE216043_10_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null lateral posterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32837 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855033 Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34563 GSE216043_10_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null 496100318_PCx_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3344 OSRC2 CCLE Cell Line Gene Expression Profiles -1.0 -2.09523 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923249 MEC1 DepMap CRISPR Gene Dependency 1.0 2.03397 Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.80979 496100489_HIP_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07156 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052696 Trophectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.159 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null K Homology domain, type 1 InterPro Predicted Protein Domain Annotations 1.0 null NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1158 lateral (parvicellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34563 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_4293_KO_Tbc1d4_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.6553 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.444499 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07694 GSE217541,GSE217543_0_v_1_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07536 LN319 CCLE Cell Line Gene Expression Profiles -1.0 -1.91248 PMC7450273-mmc2.xlsx-ST12-Unnamed_4_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null 19658189-TableS4 GeneSigDB Published Gene Signatures 1.0 null ARNT_01_307 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -1.38403 Teratoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.419 periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30213 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.893744 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37215 RPS4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60627 WDTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49497 r6 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21871 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.871855 abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.83914 Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17137 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75027 anterior paraventricular nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7035 osteocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.348148 NEFH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07308 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2473 FANCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06905 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216043_3_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.247 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 6.20024 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null hPSC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.008 PUM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00049 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33668 teratoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.732596 S462 DepMap CRISPR Gene Dependency 1.0 2.68152 Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.64066 Perturb_3679_OE_MERVL_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.73803 GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28792 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40781 OCILY19 CCLE Cell Line Gene CNV Profiles -1.0 -1.95638 GSE216043_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 GSE216043_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84715 MED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21627 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32094 regulation of macromolecule biosynthetic process GO Biological Process Annotations 2025 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE129389_0_v_4_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5913 OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.48463 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847424 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08653 HOUAI DepMap CRISPR Gene Dependency 1.0 3.39362 Substantia nigra, compact part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33139 Brain Lower Grade Glioma_LGG_TCGA-FG-5964-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null SACM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15189 Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15522 SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4419b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.0289 GSE130081,GSE130082_5_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19362 inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.866285 pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.4425 PCDHB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44522 GSE129389_0_v_1_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null KLF4-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879409 H2AFZ ENCODE Transcription Factor Targets 1.0 null Anterior cingulate area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26842 KATNBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37009 Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34826 CAL62 CCLE Cell Line Gene CNV Profiles 1.0 1.36681 CBX8 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4668-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 SNAPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29155 Taenia tecta, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30849 Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE171837_0_v_3_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61976 GGTLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63979 POLR2A ENCODE Transcription Factor Targets 1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16347 Morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.107 c-MYC_KD_GDS2526_113_human_MDA-MB-231 BREAST CANCER cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Mitotic fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043053 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.32407 GSE120413,GSE120447_4_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17547 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48629 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.08464 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.450657 SRC_overexpression_276_GSE37428 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.52877 reuniens nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02619 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46411 septopallidal part of the olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00301 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21801 RBE DepMap CRISPR Gene Dependency 1.0 2.01092 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE179002_0_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27308 Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4507 GSE112762,GSE112767_1_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF524 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1989 IMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2614 Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11592 AKAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02426 Primary motor area, Layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50007 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55937 C33A DepMap CRISPR Gene Dependency 1.0 2.05885 Female germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.478 C11orf98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02925 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NT2/D1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.614 THBS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14398 superficial stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22934 ZMIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86025 GSE206870,GSE206872_1_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Activin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.831 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3514 bladder GTEx Tissue Gene Expression Profiles -1.0 -1.38034 ChIP_POU5F1_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_13171_KD_Ncor2_SRP060657 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.92765 GSE129186,GSE129223_0_v_1_aicda_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.922863 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842374 ZC3H15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14579 GSE241036_0_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.867848 KELLY COSMIC Cell Line Gene Mutation Profiles 1.0 null RPMI8226 CCLE Cell Line Gene CNV Profiles 1.0 2.02825 GSE216043_7_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86208 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.915964 r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65776 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40319 Anterior cingulate area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24858 embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040484 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65627 SW1783 CCLE Cell Line Gene Expression Profiles -1.0 -1.81713 NLGN1_KD_GDS4759_335_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null supramarginal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.911216 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057392 molecular_function GO Molecular Function Annotations 2015 1.0 null PPARG JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null