association	dataset	threshold value	standardized value
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7306
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03923
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49921
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08969
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205787
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238943
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15465
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
Microtome section	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01277
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29523
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13703
Ciliary basal body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65906
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04117
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11237666-spectrum.03516-23-s0004.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.359682
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22685
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1152
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72187
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08064
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86114
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3138
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03654
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48472
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21914
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41481
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.566
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5083
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14127
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61012
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.685
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62806
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63332
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3088
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neostriatum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6794
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-219-SOX7_SOX7	Rummagene Transcription Factor Associations 2026	1.0	null
IF-75-AJ33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24282
Ciliary cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.431
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4823830-ncomms11171-s2.xlsx-GATA3_upregulated_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45124
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6796
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12058
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681435
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.29548
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_1_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48838
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06838
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76769
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5048
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3309
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37655
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17189
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.783
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5164
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20806
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753255
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33228
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54292
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
WD-26-EB85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464445
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5127
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47789
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23058
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21929
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370052
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7068
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38147
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38699
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58844
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20198
DA-10-ZX00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323327
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2521
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1877
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9754
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91424
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.0605
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34557
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25353
ND-36-VC68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344683
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08603
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48695
PMC8299217-mmc3.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JF-45-JM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212583
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3731
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6296
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3517
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28445
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308866
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326182
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258475
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8365
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.5526
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04369
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.501
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33473
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80959
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9444
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10725
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236649
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1939
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90488
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33707
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4898
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11583
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24538
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8178
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79125
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JE-52-BH86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254448
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225191
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43442
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96507
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886514
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43597
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29598
GSE191110_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285667
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3598
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26857
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48826
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.501
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.064
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0847
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26443
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CB-83-LF14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218439
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2183
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68086
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338486
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6363
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90235
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5118
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8373
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91706
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19926
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00711
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244247
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36958
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6454
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361601
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5035
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7844
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42126
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41165
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21955
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91314
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9992
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1729
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.848
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.8875
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41512
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55476
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16681
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18375
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26485
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37742
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12239
PMC7899452-media-4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45793
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0092
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1179
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21205
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8497
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1936
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-29-ZD04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301713
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02392
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77323
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633359
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32907
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2312
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3359
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26191
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252983
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0899
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16612
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CD-88-UF56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251893
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41933
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.994
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65967
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18395
HB-75-KT12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227278
chr12_113156317_A_C_b38	GTEx eQTL 2025	1.0	1.07862
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3134
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399056
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3341
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48372
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32351
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66477
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64293
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282953
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2971
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1711
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	77.7257
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43195
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8551
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.338
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.80074
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18353
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94578
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF555	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49256
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26238
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25033
EF-85-DA07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414095
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264922
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03173
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03693
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299698
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02111
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
UF-14-LK87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203068
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1082
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-TFAP2C_TFAP2C	Rummagene Transcription Factor Associations 2026	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8967
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247036
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0894
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50144
Caudate nucleus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12338
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22155
EF-85-DA07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268218
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442263
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.194
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49333
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4556
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181821_1_v_3_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43388
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20277
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_filtered-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39774
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82385
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66096
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06397
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21111
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34341
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25669
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333731
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5046
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35503
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03056
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321817
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277294
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42329
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8121
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6969
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3531
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5165
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.01
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7474
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332071
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471611
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9936
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2247
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1902
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Corpus striatum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34945
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1956
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7464
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340885
BA-39-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311708
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08383
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69973
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66838
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523909
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52067
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22777
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19114
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97505
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4907
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21521
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14959
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63552
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.0302
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38867
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10293
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02304
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17331
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345138
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37928
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06205
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37583
AGFG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37219
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9826
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21486
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1124
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1449
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3685
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.328
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40239
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29732
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266499
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4534
PMC12198892-pi-2025-0101-Supplementary-Material.pdf-46-PREB_PREB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72185
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9034
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07129
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16946
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09568
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43385
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0507
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26169
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227885
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57451
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21654
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35122
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82096
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36772
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.453
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1543
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.5277
Regio oralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9168
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80505
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48356
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76559
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98288
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.666471
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4699
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17431
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.983961
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54023
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1252
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16193
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.672
Orr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.777108
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101748_0_v_1_apela_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55262
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01982
Dynein axonemal particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25229
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17389
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9273
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4188
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymph	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21145
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1538
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35765
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.248
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07082
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80384
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05833
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0383
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09133
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23032
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58443
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0562
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52244
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76968
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7309
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45235
PSMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22044
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51659
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59522
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205556
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VC-19-YG34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37452
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08926
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6071
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.036
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11755
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564609
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33777
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41736
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08589
PA-40-HC94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311733
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7262
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78583
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05868
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1032
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.063
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24635
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77038
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16269
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626074
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE126402_1_v_6_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-encode-consensu_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-15-LA22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301775
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9411
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18655
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346761
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4583
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
KB-88-OR49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309095
SLC25A38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2728
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.0087
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303266
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8044433-mmc4.xlsx-Sheet1-Acute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16301
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389913
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.789
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88943
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ID-07-YY69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227371
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37704
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16834
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
MD-86-UW46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445432
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65349
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02152
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39107
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93614
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90755
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03942
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20729
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39621
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.351
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33752
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.001
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5349
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1826
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60047
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03922
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4027
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.524
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3029394-pone.0016617.s001.xls-Down-regulated-Table_S1_Genes_down-regulated_by_SOX2_over-expression_0_5-fold_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625263
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
JC-19-ST72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433019
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7971
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00139
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
GSE227698_5_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05165
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446933
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42635
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8298514-41467_2021_24813_MOESM22_ESM.xlsx-RELA_H3K27ac-SYMBOL_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11343
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.604864
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02371
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58329
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4603
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215172
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335844
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7764
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3465
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.454
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.52589
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02638
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.626
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33655
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.920992
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34465
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264415
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437247
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12005
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9588
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
XC-13-LW13_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224173
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24477
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608306
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9638
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12512047-Table2.pdf-30-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
VAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32708
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72556
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82114
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126402_5_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4517
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68467
ZNF585B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51861
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63395
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8036
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2596
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18794
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312279
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1787
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00561
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.934
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230434
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.045
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26253
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82731
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215504
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755665
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
496100600_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0786
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.084
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.126
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68369
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6791
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94823
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05354
CENPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50708
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50852
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12815
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.342
PMC11949941-DataSheet1.pdf-12-ZNF175_ZNF175	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41