association	dataset	threshold value	standardized value
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9939
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.85
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71125
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.686
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07081
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34398
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6894
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7931
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49344
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4429
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9856
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67911
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.7095
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.732
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2381
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7622
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13576
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72037
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4606
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7527
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.752
SAPHO syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1141
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.363
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.9676
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.504
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5821
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73939
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28277
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1489
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
GSE144500_8_v_11_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.634
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0267
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5469
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9658
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
496100479_FWM_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18439
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.531
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.789
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5341
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9988
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.762
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.161
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.597
NAXE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85341
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06086
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7008
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8838
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.718
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27533
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5488
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97466
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0
GSE173873_2_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36561
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.0115
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76768
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90916
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5185
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7352
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5217
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.03
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8193
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4321
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60777
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95306
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.50745
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9026
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6513
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8726
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01734
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5909
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89246
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0924
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40424
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93528
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34836
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3722
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4737
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35723
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3798
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67546
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.565
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71919
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70969
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31018
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.7679
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13561
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36853
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6069
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7804
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26109
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4877
GSE173873_12_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51803
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68542
ADAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88786
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
GSE195559_3_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36139
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.203
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6231
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09092
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LIPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58598
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2958
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24614
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3717
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47495
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5197
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3135
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4579
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9671
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9263
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19571
GSE135983_0_v_1_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53911
PKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35072
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8998
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2013
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.73446
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3244
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76663
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62418
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59545
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.8138
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0187
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7494
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34766
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-PHOX2B-fromNode_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8456
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7552
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
ZNF92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91346
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46391
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8817
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4651
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51823
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.6083
GSE173873_12_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58589
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76364
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7234
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1686
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0457
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8242
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40686
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.941
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7237
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8951
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.027
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_0_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
PMC8563805-41598_2021_858_MOESM2_ESM.xlsx-Supplementary_Info_6-Gene_List_6_The_list_of_human_orthologs_of_the_downregulated_fly_DEGs_identified_from_TRAP_control_vs_PARIS_wild_type_comparison_ZNF746	Rummagene Transcription Factor Associations 2026	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9545
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6579
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2279
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0287
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5588
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3354
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08746
Fc-epsilon receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3717
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13154
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0348
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.4561
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0359
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7398
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6322
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61446
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07362
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0832
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.98373
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null