association	dataset	threshold value	standardized value
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Integrin alpha7-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
IGF1_OE_GDS3484_542_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58339
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21898
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44132
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90647
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
18544678-Table2	GeneSigDB Published Gene Signatures	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS698T	CCLE Cell Line Gene Expression Profiles	1.0	1.44114
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76046
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99481
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-455-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.42572
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78443
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7619
hsa-miR-4708-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08113
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35754
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39773
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827781
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_3W_vs_LS_3W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90164
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03071
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7035
haloperidol-418	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4689	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-542-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE233679_6_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06471
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22318
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08532
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11191
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36561
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36895
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37991
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844027
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63911
SNU308	CCLE Cell Line Gene CNV Profiles	1.0	1.33038
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.85568
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36115
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36371
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967008
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23123
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14833
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00509
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29795
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60252
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39885
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cobalt chloride-383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972567
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pirinixic acid-495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91232
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33584
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61196
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50661
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97323
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4293
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881268
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09951
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9431
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10395
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98932
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22636
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9123
Acute Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TM31	CCLE Cell Line Gene Expression Profiles	1.0	2.65561
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3312
mepenzolate bromide-3748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95493
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
hsa-miR-4681	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35952
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05661
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954562
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283784
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62235
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847753
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910062
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925851
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890339
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06476
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05483
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9477
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961291
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3029
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07087
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59765
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63597
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
tanespimycin-432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.613
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57568
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08812
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71868
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56531
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.91024
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33262
Becker muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1331
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92296
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01854
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3939
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11518
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43276
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1905
PRX	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
myricetin-4090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910022
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09267
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18202
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55317
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.84807
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98568
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24507
Dementia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Embryonic syncytium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
Brain myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.959
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	2.3968
fulvestrant-310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.234174
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17745
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52615
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06919
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.069119
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928837
H2BK12ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6671
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934884
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59453
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2292
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966069
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15412
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
synaptic signaling	GO Biological Process Annotations 2025	1.0	null
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48702
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36837
Charcot-Marie-Tooth disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14885
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.224
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4097
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16975
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.16197
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70333
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01609
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855658
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24757
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23048
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887107
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19962
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040664
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22741
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.902618
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35173
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5394
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959018
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69726
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80705
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849679
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27262
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83497
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03569
HCC70	Achilles Cell Line Gene Essentiality Profiles	1.0	1.47503
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8668
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831442
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08464
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59523
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37065
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69731
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4327
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62433
bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37959
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
DMS53	CCLE Cell Line Gene Expression Profiles	1.0	1.75995
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08934
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98967
RCOR1	ChEA Transcription Factor Targets	1.0	null
alexidine-7397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3838
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48224
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2036
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84716
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06236
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992443
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847707
hsa-miR-4745-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81459
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61696
hsa-miR-4701-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.885419
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00331
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.6551
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
hsa-miR-3130-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16474
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29923
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09972
NCIH1395	CCLE Cell Line Gene Expression Profiles	1.0	1.59339
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03441
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5185
GSE134896_0_v_7_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949211
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9276
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53597
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.58182
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.936327
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2995
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846527
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09287
E2F1	ChEA Transcription Factor Targets	1.0	null
deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.600479
colchicine-4614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.169
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900472
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992312
copper sulfate-438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82194
Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.06296
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05334
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.02532
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42958
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904463
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80097
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02629
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64212
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824306
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86868
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00747
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255901
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27264
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850043
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56988
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59554
hsa-miR-4444	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3416-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2296
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.925951
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.047
u87	HPA Cell Line Gene Expression Profiles	1.0	1.48614
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	4.06936
Neuromuscular disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Extensor digitorum brevis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8528
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61776
schizophrenia	GAD Gene-Disease Associations	1.0	null
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55747
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872012
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07622
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20819
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07985
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0609
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32557
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.67162
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.43184
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41618
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58427
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06323
COLO704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65155
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.074519
Lateral loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.409
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84775
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-175-VII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27132
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84171
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887684
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10938
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0234
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901653
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40184
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15998
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5742
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3979
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27237
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905327
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44913
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06781
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58578
novobiocin-499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13327
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
hsa-miR-4697-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874903
H2BK20ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thioperamide-4675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38049
L-periaxin-Drp2 complex	CORUM Protein Complexes	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19185
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40225
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease intermediate type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
Myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.93
A_CA_04_2009_7dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76913
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27437
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927923
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00777
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360974
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5445
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56988
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27488
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.021
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83544
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
ciprofloxacin-1522	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45605
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41907
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99096
Epineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
17683608-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1144
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.93733
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33949
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28799
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7193
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.33077
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
spiradoline-4553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2079
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831571
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00662
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.975868
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02446
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09983
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70943
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9864
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1005	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.45348
LY-294002-501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69351
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15265
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86887
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pluteus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6771
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Reactome Pathways 2024	1.0	null
20003503-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958251
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47563
hsa-miR-4708-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48283
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33677
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21809
mla144	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834241
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
RUNX1_01_245	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.62886
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12934
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.812
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78659
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02215
LOXIMVI	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
PMC4664757-mmc3.xlsx-RX-Indian_Gene_RAX	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
Schwann cell microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.15
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.04861
DD-48-MZ39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232809
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3887
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36613
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39259
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04684
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917459
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833551
Fukuyama congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954313
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16269
PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-5-HEY2_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9306
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01904
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5242
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3348
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7872
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.26985
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.59298
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SF539	CCLE Cell Line Gene CNV Profiles	1.0	1.45664
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29913
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24998
Muscular dystrophy-dystroglycanopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
ILF2_02_152	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61005
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.82332
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894506
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34157
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19169
hsa-miR-3925-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TYKNU	CCLE Cell Line Gene Expression Profiles	1.0	3.39177
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876793
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.84073
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61897
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966012
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32229
genistein-268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.891631
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	4.28576
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.52718
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64718
CSTB_KO_GDS5090_199_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01582
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01533
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00091
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955997
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56614
prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20389
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00401
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50795
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16796
C99	DepMap CRISPR Gene Dependency	1.0	3.19012
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09805
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75279
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17319
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76724
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39547
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
Necrosis	CTD Gene-Disease Associations	1.0	1.11843
NCI-SNU-5	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
DTNA	Pathway Commons Protein-Protein Interactions	1.0	null
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06163
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.97611
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-OHPL-1826-SM-2YUN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01937
BT16	DepMap CRISPR Gene Dependency	1.0	3.15355
EF-hand domain, type 1	InterPro Predicted Protein Domain Annotations	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81513
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93305
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943547
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51889
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.409388
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055224
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paranoid schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
Lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15138
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.32946
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0377
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937582
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.72209
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04364
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54685
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PPARD_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03076
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2762
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44935
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07805
LAN2	DepMap CRISPR Gene Dependency	1.0	8.09171
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62894
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59505
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HT-01A-61R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02114
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87959
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33473
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.837
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849679
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04591
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899233
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5465
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852941
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13788
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5251
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67463
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
deafness-dystonia-optic neuronopathy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
SF268	COSMIC Cell Line Gene Mutation Profiles	1.0	null
15-delta prostaglandin J2-201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6667
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1899
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26184
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960222
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21817
probucol-592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5107
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55383
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54422
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01897
hsa-miR-3151	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
acetylsalicylic acid-6924	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926441
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36897
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21883
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.27902
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
HCC-78	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24307
Amphetamine-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880514
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
CRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18838
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18713
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909171
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.867
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.63501
NCIH2452	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04694
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43045
TNRC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84361
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909622
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01275
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837036
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48006
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18024
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.742089
hsa-miR-1287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.39754
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.73109
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5926
hsa-miR-1276	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62799
vitexin-4413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stromal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05374
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23452
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93254
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62108
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85182
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2626
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49224
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03493
kanamycin-4625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alpha-estradiol-762	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98942
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06101
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2608
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044616
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38049
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37646
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052854
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90326
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266251
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857623
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06256
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89765
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70834
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.21831
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94876
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20054
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.168
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
SOX2	ChEA Transcription Factor Targets	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66899
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5066
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22092
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6443
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894169
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.17431
AP1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95469
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93361
chlorpromazine-419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-1910	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
hsa-miR-4283	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4302
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00526
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09188
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44217
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892013
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87693
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29967
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12373
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78584
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875612
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63896
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055811
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69913
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5807
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79516
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20455
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tetraethylenepentamine-498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.685
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.798859
Hypertension	CTD Gene-Disease Associations	1.0	1.06008
TOV21G	DepMap CRISPR Gene Dependency	1.0	2.35262
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54424
hsa-miR-2115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.359
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882429
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38259
NMDA selective glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76272
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10844
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	2.581
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3651
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30867
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38083
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33209
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17734
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.851245
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85768
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06665
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966488
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10744
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69285
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	5.92821
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231486
quinpirole-456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
3-aminobenzamide-590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71042
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	2.02814
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.3953
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16719
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.220321
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81319
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9407
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905367
MAPK1_knockdown_131_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56001
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886872
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45613
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39326
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
organelle	GO Cellular Component Annotations 2015	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.08584
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836635
PMC4664757-mmc3.xlsx-RX-Indian_RAX	Rummagene Transcription Factor Associations 2026	1.0	null
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-3127-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KINGS1	DepMap CRISPR Gene Dependency	1.0	4.54103
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19707
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46783
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55945
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974136
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53605
NU-1025-608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.00224
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511112
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A199-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.2713
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.40176
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94815
Autosomal dominant distal hereditary motor neuronopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.883
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.034996
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32235
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40706
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01965
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75252
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0775
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50772
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84266
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61221
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950083
Inflammation	CTD Gene-Disease Associations	1.0	1.17366
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.838193
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0721
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26508
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
Charcot-Marie-Tooth disease axonal type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04626
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10052
KU812	DepMap CRISPR Gene Dependency	1.0	6.39115
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2884
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12615
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00879
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16506
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96664
FOS	ENCODE Transcription Factor Targets	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8574
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05374
GT3TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.67324
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07211
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.549
upper basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12182
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45707
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46449
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922676
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72436
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04009
Learning Disorders	CTD Gene-Disease Associations	1.0	1.06479
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06936
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30447
ovary	HPA Tissue Gene Expression Profiles	1.0	0.903875
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32725
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04716
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11316
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.39547
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824046
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4763
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clofibrate-263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17999
Bipolar Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3385
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23134
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_7Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.30462
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01786
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827579
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06956
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03735
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37967
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38741
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4368
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
Integrin alpha6-beta4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.381
SNUC2A	Achilles Cell Line Gene Essentiality Profiles	1.0	1.60161
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14613
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93539
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91794
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.6798
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.39908
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67678
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01786
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837981
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97119
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01746
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42901
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F2_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52893
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6974
hsa-miR-4635	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Peripheral nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46636
Ulnar neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57364
SLC1A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9803
oxamic acid-439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5647
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72964
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79611
AML193	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29026
C32	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27352
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08404
hsa-miR-4272	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KALS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.93609
postcentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946712
PMC4664757-mmc3.xlsx-RX-Chinese_RAX	Rummagene Transcription Factor Associations 2026	1.0	null
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63706
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58057
HMCES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89816
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26043
flufenamic acid-316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73397
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.050406
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.51089
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12738
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.57218
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09548
EZH2	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62613
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90144
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
hsa-miR-4651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
PMC6411037-NIHMS981149-supplement-4.xlsx-Table_S3E-Table_S3E_Result_of_GSEA_with_human_ST-EPN-RELA_gene_set_DEGs_in_PDGFA_tumors_relative_to_RELA_fusion_tumors_are_listed_in_the_table_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Spectrin/alpha-actinin	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01786
hsa-miR-3668	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.0531
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07312
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH684	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24035
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.22902
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46888
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58618
Charcot-Marie-Tooth disease type 4H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
hsa-miR-4646-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11271
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14746
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37245
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847508
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06665
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56713
CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3637
ARH-77	GDSC Cell Line Gene Expression Profiles	1.0	1.80797
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5421
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48495
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09089
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977584
neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602088
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6097
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46024
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.53215
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4758-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00162
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19419
pentamidine-639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4688	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
hsa-miR-520a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
amylocaine-4169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65596
Charcot-Marie-Tooth disease type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00007
Nonorganic Psychosis	DisGeNET Gene-Disease Associations	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.095951
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13293
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04635
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24623
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959226
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12574
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95119
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940486
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1536
Dystrophin-related protein 2	InterPro Predicted Protein Domain Annotations	1.0	null
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40815
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4183
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78778
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09103
nerve	GTEx Tissue Gene Expression Profiles	1.0	2.18795
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69041
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0054
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.68076
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19963
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050815
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22287
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1757
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9828
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857531
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15648
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
PMC7940623-41467_2021_21725_MOESM11_ESM.xlsx-Extended_data_table_9_regulons-ATF3_extended_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20679
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
amiodarone-4657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06961
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7133
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral white matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41582
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33667
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42429
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926157
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
PRC2_SUZ12_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993766
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4841
lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4306	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.44284
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
CRCGN013_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1563
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32749
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
charcot-marie-tooth disease type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.33327
NB10	GDSC Cell Line Gene Expression Profiles	1.0	1.71222
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.7139
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1169
biological_process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.32475
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27384
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890371
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919461
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27658
schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38139
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21478
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48209
EF-hand domain pair	InterPro Predicted Protein Domain Annotations	1.0	null
NCIH841	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.74676
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.63568
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07695
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56713
CRCGN015_MCF10A.TP53.M_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02528
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.22696
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42212
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973999
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0881
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852338
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1144
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56044
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21164
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203026
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81173
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85437
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6533
Glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968236
dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218563
NCI-H2052	GDSC Cell Line Gene Expression Profiles	1.0	1.66577
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4384
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1171
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
ciclosporin-602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63748
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831735
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.873888
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1804
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89445
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3912
hsa-miR-4319	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895908
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.302168
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18145
HT1080	CCLE Cell Line Gene Expression Profiles	1.0	1.79484
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12983
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23367
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64188
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02548
Charcot-Marie-Tooth disease type 1E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.837
hsa-miR-330-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01786
hsa-miR-3975	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SF539	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58562
dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.839187
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brachial plexus neuritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07609
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16032
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77659
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.89625
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34429
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.889179
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84713
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0615
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ABL1_knockdown_137_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.6058
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051255
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2298
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.59874
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52285
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.338
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79554
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0083
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78301
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
butein-607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.15425
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.17794
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
hsa-miR-378g	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09123
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71423
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984495
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15914
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11947
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31087
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11191
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	2.30396
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01884
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97026
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.848
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85362
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25789
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93496
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05848
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374618
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23004
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35101
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987995
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39492
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55941
T-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67344
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4165
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68224
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39895
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43654
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22091
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38449
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39181
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54546
SP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05635
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0963
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61271
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7671
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32725
AMO1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03365
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41828
PMC13127299-mmc2.xlsx-FOXM1_kdRNAseq-hgnc_symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Walker-Warburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52078
GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10274
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842525
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8311
troglitazone-462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-711	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
TNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17189
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05327
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.65
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871991
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental Biology	Reactome Pathways 2024	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24064
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69216
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.54655
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02443
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48089
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22016
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-0.894004
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3678
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6636
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.180339
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09108
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98625
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17147
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08823
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04108
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20882
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67244
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8883
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90544
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53499
Hypertrophy	CTD Gene-Disease Associations	1.0	1.01212
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82671
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1641
Weight Loss	CTD Gene-Disease Associations	1.0	1.04831
PMC9404924__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN014_HEPG2_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51542
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00254
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973586
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25815
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05047
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6105
hsa-miR-4793-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837682
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13841
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
A_CA_04_2009_7dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75618
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.33514
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57896
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04307
MS751	DepMap CRISPR Gene Dependency	1.0	2.53754
chrX_101140128_A_G_b38	GTEx eQTL 2025	1.0	1.19563
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02605
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.224
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80613
CRCGN017_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1412
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03441
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04151
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33576
hsa-miR-4436a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54551
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1693
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5749
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52252
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43601
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64904
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
hsa-miR-1246	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.794525
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.780648
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835115
HPBALL	CCLE Cell Line Gene Expression Profiles	1.0	1.90591
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91779
hsa-miR-4481	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26235
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01978
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975957
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4881
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
TFAP2A	ChEA Transcription Factor Targets	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04506
Mesaxon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17616
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834241
GTEx Vagina 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	3.07756
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29416
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936759
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51814
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3584
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14866
MKN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57866
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.034145
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872457
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31948
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5439
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38976
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.14445
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3031
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836771
Paranodal junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.659
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03253
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99847
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46096
myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289199
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17283
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04972
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18579
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00254
hsa-miR-1233	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34438
Internode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3593
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.266
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967265
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940735
Charcot-Marie-Tooth disease type 2J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
C80	DepMap CRISPR Gene Dependency	1.0	2.72799
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5932
hsa-miR-936	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77323
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96784
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95834
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56549
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83497
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18337
calycanthine-5744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sodium phenylbutyrate-434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4644	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43992
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88436
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49595
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5887
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43396
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.06253
tetraethylenepentamine-405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3616
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
fluoxetine-6757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Charcot-Marie-Tooth disease type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
H3C10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01377
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00653
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
betulinic acid-4101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
laminin-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.284
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12017
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04176
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52561
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23126
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital muscular dystrophy-dystroglycanopathy type A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24796
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71038
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.202
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.966539
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949093
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.912
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16204
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
PCDHB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23506
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77723
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57558
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10726
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.58346
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.196339
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37517
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60114
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066931
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181798
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71848
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.615
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876095
LM-1685-253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.867
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91819
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43109
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04083
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.51898
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4176
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7002
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16916
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052372
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.21272
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58624
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78479
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9829
tioguanine-642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
monorden-484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941167
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DAG1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08071
GSE130715_2_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33707
CRCGN015_HEPG2_48H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22927
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55199
rh30	HPA Cell Line Gene Expression Profiles	1.0	2.18765
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28748
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
PMC4664757-mmc3.xlsx-RX-Chinese_Gene_RAX	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72711
neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.172201
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9869
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.913617
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36084
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49791
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30867
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20792
GSE90019,GSE90020_1_v_3_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24223
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30486
charcot-marie-tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.777795
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.04201
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29306
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25576
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23861
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912053
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10866
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0746
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54404
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3180-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.567
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36492
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05581
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05849
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.891862
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9205
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06969
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11965
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63227
myoclonic-atonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855549
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.34904
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12596
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.02039
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21655
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91323
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63134
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33777
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34748
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18168
FIBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27535
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
Charcot-Marie-Tooth disease dominant intermediate C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
CEBPB	ENCODE Transcription Factor Targets	1.0	null
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10667
tretinoin-384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41466
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41347
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39941
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00999
primaquine-4845	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
levomepromazine-7399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828443
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.940526
hsa-miR-761	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854499
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64167
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.5966
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256902
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00874
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.67033
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13092
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.02271
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17778
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00887
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16562
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38685
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4812
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61137
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958293
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32593
Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3631
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14109
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.7566
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09588
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840751
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.321
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24319
GATA2	ENCODE Transcription Factor Targets	1.0	null
Congenital merosin-deficient muscular dystrophy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06165
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837254
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0541
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.940971
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41504
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00254
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.940195
pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860745
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14799
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29035
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56465
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02935
thiocolchicoside-5095	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02172
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.895976
3-acetylcoumarin-4664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1678
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99028
flufenamic acid-5059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5118
Paranoid Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59247
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.871082
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11518
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17473
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836319
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945375
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72803
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52909
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.326078
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892945
Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atrophic muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.392629
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77262
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.03752
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02857
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65147
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83334
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09078
5666823-609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21086
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09737
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2351
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868529
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00944
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77389
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69009
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930225
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23995
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.39934
HCC827	Achilles Cell Line Gene Essentiality Profiles	1.0	1.68102
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938162
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933437
hsa-miR-4505	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967884
LY-294002-258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9891
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8053
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70926
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57877
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2716
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37678
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47139
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13356
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.40699
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05912
cinchocaine-4149	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5936-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0026
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35607
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66885
TAL1_01_217	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.88151
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.55354
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95125
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26058
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.510344
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83161
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48409
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.47374
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31664
LK2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.50905
THP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17484
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99516
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
hsa-miR-3688-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12275
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68605
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17553
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU46	DepMap CRISPR Gene Dependency	1.0	2.54576
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8765
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32628
hsa-miR-4482	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9154
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2373
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976592
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33928
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7987
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93964
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21039
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06522
D341MED	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52222
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5797
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38831
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
tolnaftate-4221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984562
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906591
JHUEM7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75973
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906591
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54932
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.857883
hsa-miR-3157-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47935
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00787
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.184
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95874
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85919
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13714
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39424
hsa-miR-3622a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
hsa-miR-3924	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852689
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.41966
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58005
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56822
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40706
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861188
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56344
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.59041
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Cocaine	CTD Gene-Chemical Interactions	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61824
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18699
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965441
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.70545
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23594
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0095
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947864
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54948
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62605
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
valproic acid-497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32901
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415172
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prestwick-1103-7317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Charcot-Marie-Tooth disease dominant intermediate B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78025
SNU1105	CCLE Cell Line Gene Expression Profiles	1.0	1.57903
nortriptyline-7300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tretinoin-224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21236
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13938
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.4368
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75498
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
SYK_KD_GDS3609_441_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1883
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.0337
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924796
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0939
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906591
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.646911
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6787
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08915
LCLC-103H	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26193
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44238
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54866
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2767
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15374
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02219
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03889
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52862
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
intracellular part	GO Cellular Component Annotations 2015	1.0	null
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4518
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91378
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34878
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
node of ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.750904
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61759
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
monastrol-596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prestwick-665-7380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15921
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09422
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907179
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95265
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24279
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMD	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69927
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0595
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UMC-11	GDSC Cell Line Gene Expression Profiles	1.0	2.96792
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41998
brain	HPA Tissue Gene Expression Profiles	1.0	1.8771
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19252
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06032
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02273
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861122
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904446
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4385
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
zaprinast-6749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879618
Charcot-Marie-Tooth disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09737
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25335
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2174
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0339
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7214
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
EF-hand domain, type 2	InterPro Predicted Protein Domain Annotations	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0253
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59856
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60521
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057868
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1563
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82676
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82507
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03526
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2198
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.138
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41024
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38134
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67768
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9499
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myocardial Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
Neuron projection branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40754
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital myasthenic syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66956
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59837
ACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92729
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3687
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14896
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17134
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
ME-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.305726
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3588
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285876
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888832
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909994
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50475
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20087
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929037
PBK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4743
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842964
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4075
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28574
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90784
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5542
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.523
canadine-4020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4322
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0764
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52313
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dendritic branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03763
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
Kco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
PCI30	DepMap CRISPR Gene Dependency	1.0	2.0973
D423MG	DepMap CRISPR Gene Dependency	1.0	4.83027
hsa-miR-140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66843
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
NCIH2170	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48298
Developmental and epileptic encephalopathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21853
hsa-miR-4297	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55556
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.728868
hsa-miR-4726-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64288
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.48027
ROMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06257
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2557
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923758
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78945
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875596
A549	GDSC Cell Line Gene Expression Profiles	1.0	1.52475
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44492
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02213
sodium phenylbutyrate-408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	3.20574
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14335
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1468
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957695
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.386
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62684
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3912
REST	ENCODE Transcription Factor Targets	1.0	null
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.376
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17371
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.59319
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HS729	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01078
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23301
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59618
Charcot-Marie-Tooth disease type 2I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971622
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.982255
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25488
WW domain	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52475
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47731
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837981
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2624
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60283
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.17095
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4133
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35913
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11772
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835683
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18696
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26486
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08919
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49045
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.840669
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29782
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66938
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997998
BICR10	DepMap CRISPR Gene Dependency	1.0	3.9366
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A5YI-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.867
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15951
HARA	DepMap CRISPR Gene Dependency	1.0	3.99941
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83721
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28079
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.79711
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5624
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79957
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25513
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74845
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.50285
(+)-chelidonine-5760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45365
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.883
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.735397
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71671
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.288829
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22662
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910926
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22139
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.647
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04239
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0397
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.392629
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.64034
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06308
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ICC2	DepMap CRISPR Gene Dependency	1.0	2.46111
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44975
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05673
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954143
16513838-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0681
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96288
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95739
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863231
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17948
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.788442
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2566
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9769
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18699
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5714
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5614
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73023
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70802
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925779
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27912
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43656
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.954703
KDM5A	ENCODE Transcription Factor Targets	1.0	null
josamycin-4631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79286
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41229
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94722
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44469
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.95091
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10475
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41311
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.023
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825694
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48733
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83564
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.01512
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00323
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47909
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.77196
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68817
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2033
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09549
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987166
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1262	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
bff3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
JUN	ENCODE Transcription Factor Targets	1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55906
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83931
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00004
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899989
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0942
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80205
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
sodium phenylbutyrate-502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85844
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88175
phenelzine-2357	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04992
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38206
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24624
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42347
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_downreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40877
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49857
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03235
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84212
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45852
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSTB_KO_GDS5090_398_mouse_cerebella	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.869888
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0064
amitriptyline-167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19551
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876516
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13394
hsa-miR-185	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01321
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96607
hsa-miR-101	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47111
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.953593
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00533
disopyramide-7276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.222
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903046
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11173
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96881
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997796
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUB1_02_161	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65208
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897034
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39503
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88645
Polyneuropathy	DisGeNET Gene-Disease Associations	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63649
Congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40086
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27581
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96372
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30218
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00216
Acute-Phase Reaction	HuGE Navigator Gene-Phenotype Associations	1.0	null
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04759
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947864
MB1	DepMap CRISPR Gene Dependency	1.0	2.34557
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2594
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29247
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.062895
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254336
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92896
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61976
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.877617
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274744
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02966
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12662
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317737
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05157
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03761
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07556
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977433
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9625
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845972
NCIH2126	DepMap CRISPR Gene Dependency	1.0	3.22281
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936046
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880044
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47495
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06347
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900663
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0567
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
CBX8	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00979
HIPK2_knockout_171_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.588144
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72011
ES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40093
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15519
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2297
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00806
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35034
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89625
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11191
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00235
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987478
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54727
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966806
Superior colliculus, motor related, deep white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25158
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08433
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1722
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48664
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19726
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9397
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940457
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929366
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912542
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27507
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24053
hsa-miR-4694-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8424
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03826
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55445
hsa-miR-940	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0419
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51521
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61628
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872141
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03883
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11817
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54545
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09177
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0534
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94861
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.119
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66276
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23002
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.85835
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10075
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3964
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9353
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905817
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6863
midodrine-7156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lingual gyrus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827904
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34656
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48794
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43418
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09308
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.40932
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.061
Myelin sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.959
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72247
Charcot-Marie-Tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.461
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-0.963149
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16221
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38506
hsa-miR-214	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97155
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61701
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.71004
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47394
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92851
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933672
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89502
Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00872
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMC-G1	COSMIC Cell Line Gene CNV Profiles	1.0	2.15465
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853575
Fatty Liver	CTD Gene-Disease Associations	1.0	1.03345
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31279
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8362
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38203
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.93367
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76995
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41164
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826397
rofecoxib-256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.65801
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Shared Paranoid Disorder	DisGeNET Gene-Disease Associations	1.0	null
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01665
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3509
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GRM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63974
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07362
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10237
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.27329
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43944
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13092
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.224
hsa-miR-3619-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34994
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.09407
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851556
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1871
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
XPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03981
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97269
hsa-miR-525-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CC2D1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63004
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02521
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04506
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05484
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.66397
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41187
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
PMC3590650-bjc2012518x7.xls-Sheet1-Supplementary_Table_S3_list_of_predicted_target_genes_for_miR29c_present_in_both_PITA_and_Targetscan_predictions_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.09733
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3458
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.83694
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41156
indapamide-3778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8046
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64688
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06342
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49196
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11808
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31065
PMC6718408-41467_2019_11884_MOESM9_ESM.xlsx-YAP1_RELA_DEGs_mice_human-Human_Gene_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949843
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52222
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38864
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3328
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33964
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871591
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73085
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908043
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828167
CRCGN008_HEPG2_24H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13825
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21915
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.505
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968748
hsa-miR-134	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.50539
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16257
PMC10304636__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23789
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46652
SMZ1	DepMap CRISPR Gene Dependency	1.0	3.82831
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26114
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0714
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27221
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11063
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30688
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
celecoxib-252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67292
X-linked agammaglobulinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22326
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.38021
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29219
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971866
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87235
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37965
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10765
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24398
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF4_02_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60145
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65388
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8679
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837969
GSE233679_6_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60725
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70216
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7198
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891731
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63297
NCIH3255	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50444
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.09621
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1672
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04313
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31013
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61895
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11502
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09943
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08488
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81457
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13343
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878097
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51727
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31518
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943893
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73612
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95041
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71901
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94876
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17445
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TD-29-IN36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213206
HS742T	CCLE Cell Line Gene Expression Profiles	1.0	1.65621
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27341
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77394
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15916
cyclic-nucleotide phosphodiesterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.644569
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874504
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28581
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76639
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.998475
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.996103
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
estradiol-665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tacrolimus-169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3965
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38805
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24878
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51707
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53322
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47123
hsa-miR-3688-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.658818
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06074
Neuropathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.39966
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943604
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.79115
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48887
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29269
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36178
hsa-miR-125a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10237
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44453
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10817
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49151
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826683
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75649
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1442
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44197
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895809
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50966
telenzepine-7419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3978	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19399
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4640-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.964
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923048
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83497
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-HEP-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42188
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53495
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH196	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.25033
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30503
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24491
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98357
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26052
Mewo	GDSC Cell Line Gene Expression Profiles	1.0	1.71598
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43126
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.54705
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08464
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52132
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43149
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09308
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32628
hsa-miR-1233	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2887
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03175
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60855
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997659
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.959333
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05551
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.29511
HS606T	CCLE Cell Line Gene Expression Profiles	1.0	1.39968
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98805
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.379322
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19637
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03732
KMRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79875
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50619
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04324
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41738
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9711
body weights and measures	GAD Gene-Disease Associations	1.0	null
TYK-nu	GDSC Cell Line Gene Expression Profiles	1.0	1.92315
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879525
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98906
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61264
GSE171826_1_v_3_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
enoxacin-4655	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27957
CRCGN011_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0984
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.26396
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52824
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9362
chrX_100762653_G_T_b38	GTEx eQTL 2025	1.0	1.51064
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65147
NCIH1993	DepMap CRISPR Gene Dependency	1.0	6.83086
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63979
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95275
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55386
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.3233
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59513
NFATC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15393
NB69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959048
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828328
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126108
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.28257
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20448
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045946
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08947
Schizophrenia, Paranoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843157
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8447
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41272
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10995
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38259
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44806
KNS42	DepMap CRISPR Gene Dependency	1.0	2.69729
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24065
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.867
PMC9378837-Table_3.xlsx-ESR1_upstream_regulators-2000-2021_QIAGEN_All_rights_reserved_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47426
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08623
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87622
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832266
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04279
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47182
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24336
CRCGN014_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79058
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00979
A2058	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.3302
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38718
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.897658
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88852
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904033
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27542
OCRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29547
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28949
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92257
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938714
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48677
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72995
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052181
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79514
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
hsa-miR-3118	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861248
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29282
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74035
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958882
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5245
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24228
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06849
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12621
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892688
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886992
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.196339
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.983665
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837338
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12757
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2555
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844123
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17126
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65147
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.999674
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74798
haloperidol-1955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48202
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36973
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13394
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36885
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09736
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04461
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997675
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90316
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46137
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24454
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937887
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4818
thalidomide-1411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53033
KE37	CCLE Cell Line Gene Expression Profiles	1.0	2.09836
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.79399
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system development	Reactome Pathways 2024	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13062
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99152
pirinixic acid-487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53792
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38124
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858887
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33109
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5856
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875039
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33834
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81655
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02483
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82117
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2838
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12059
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54035
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31674
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.27505
prednisolone-265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1052
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26958
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958228
OAW42	DepMap CRISPR Gene Dependency	1.0	5.95071
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83497
hsa-miR-4535	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88281
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05661
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.667
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16975
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852028
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04519
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
hsa-miR-3174	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
HEY	DepMap CRISPR Gene Dependency	1.0	3.18972
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	1.13871
brain	GTEx Tissue Gene Expression Profiles	1.0	1.07603
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15963
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9989
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.273
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08638
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32559
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
Body Weights and Measures	dbGAP Gene-Trait Associations	1.0	0.263458
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Calu-6	GDSC Cell Line Gene Expression Profiles	1.0	1.47293
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21754
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.65717
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48147
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.51176
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66674
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842385
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67032
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04803
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60912
hsa-miR-144	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QC-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947129
ARHGEF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46838
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.85532
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18544678-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26674
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11693
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847764
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.051
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2708-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.963535
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	-1.0	-0.967666
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63227
SW948	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37512
CORL23	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14721
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NMCG1	CCLE Cell Line Gene Expression Profiles	1.0	2.08141
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6999
Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40948
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64278
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67968
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.428
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85045
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919267
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primaquine-4263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945055
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MSGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75027
gemfibrozil-2277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.95031
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13321
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11297
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56713
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37971
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paclitaxel-640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04979
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.05654
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46279
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05999
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54547
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887065
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873025
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84537
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51749
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827844
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854152
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.04543
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.51188
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55349
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6638
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33725
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53733
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29901
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87941
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886813
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38111
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87212
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16719
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16447
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30078
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
HCC366	DepMap CRISPR Gene Dependency	1.0	3.64359
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861155
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
zimeldine-4609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862348
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44008
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17345
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77253
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95569
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315729
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920136
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91793
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28707
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1829
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8505
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42353
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Type 2 diabetes mellitus_Muscle tissue_GSE12643	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48167
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21476
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01305
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21309
Schmidt-Lanterman incisure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.155
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243049
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.93508
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5052
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
trichostatin A-332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863632
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74785
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53851
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045656
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00955
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63374
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.06681
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24855
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05181
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9196
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00345
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
127399	DepMap CRISPR Gene Dependency	1.0	2.09345
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04377
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.59999
SARS-CoV MA15_Day4-C57BL-6_None_GSE40824	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.45783
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.4008
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17322
OSC20	DepMap CRISPR Gene Dependency	1.0	2.82242
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.265
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5729
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
Oligodendroglioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79052
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4446-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54145
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34617
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77105
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0509
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.909141
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97467
Apical recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3364
haloperidol-492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5437
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.104887
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UTRN	Pathway Commons Protein-Protein Interactions	1.0	null
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4746
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.77812
capsaicin-4612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27244
main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.284769
Lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7339813-Supplementary_Data2.docx-47-PRDM1_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19419
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52561
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90448
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03883
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852061
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.578
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924858
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.618
NCI-H1666	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76678
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14865
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4436
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
SW1710	GDSC Cell Line Gene Expression Profiles	-1.0	-2.15572
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21987
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834241
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923758
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243255
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0827
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08314
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61569
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU-19-19	GDSC Cell Line Gene Expression Profiles	1.0	1.81505
pheneticillin-5763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34828
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35045
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10699
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53485
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3179
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.48038
PMC9378837-Table_3.xlsx-ESR2_upstream_regulators-2000-2021_QIAGEN_All_rights_reserved_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27607
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3151
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28914
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.52455
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37069
Zinc finger, ZZ-type	InterPro Predicted Protein Domain Annotations	1.0	null
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-134-HOXC12_HOXC12	Rummagene Transcription Factor Associations 2026	1.0	null
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.67052
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845242
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83589
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6251
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.21434
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64413
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2278
hsa-miR-4489	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24558
hsa-miR-661	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.84968
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01362
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26786
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.1945
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13422
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82061
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05804
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Charcot-Marie-Tooth disease type 4F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.113
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73669
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41042
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53081
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050859
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82455
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_143_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4014
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	7.57379
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07986
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35271
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835293
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15308
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18253
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85389
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
ST-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.15405
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87131
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.40102
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66305
peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.546256
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03686
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57091
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66869
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971755
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16883
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16484
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63155
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35197
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56696
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211437
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
SF268	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15974
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86495
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26649
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80241
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.57675
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28027
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09554
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923854
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95381
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.788021
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20901
genistein-638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14715
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21656
Twig	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21199
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01462
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95747
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.0608
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874374
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4678	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27471
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.882662
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832022
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-921	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07115
hsa-miR-4276	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
cytoskeleton	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03104
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855254
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847192
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859473
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16104
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961111
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3007
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26222
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61321
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.63699
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873002
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1718
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.81989
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
LC1SQ	DepMap CRISPR Gene Dependency	1.0	6.41295
Spectrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.47815
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30497
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32725
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26233
minocycline-5077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Charcot-Marie-Tooth disease axonal type 2S	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73131
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12093
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52012
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06488
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53067
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.64137
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203542
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03538
BC3C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49154
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.45029
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30166
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
HCC2450	DepMap CRISPR Gene Dependency	1.0	2.18641
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513476
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44571
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37512
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09526
lower dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17696
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54777
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.567
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23974
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19616
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830315
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39707
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3412
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04009
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.26607
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.6238
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
docosahexaenoic acid ethyl ester-664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5139
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02947
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.58355
PMC9160457__F9	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95055
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28748
hsa-miR-125b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_376_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00532
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28897
monastrol-610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052332
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950344
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33294
resveratrol-595	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36377
calcium folinate-7401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XGQ4-1026-SM-4AT4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918223
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17055
hsa-miR-4757-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54527
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40225
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90589
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Membrane stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85856
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.5519
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44249
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14011
GIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33838
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52346
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.69504
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.871806
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953878
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10328
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58364
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.59765
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20148
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67447
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48882
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923001
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885503
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2726
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979021
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17156
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09731
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
butirosin-666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860371
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.94518
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02467
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8711
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5323
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83497
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825108
NONO_02_149	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63227
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.935133
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51032
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849679
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48771
Polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916758
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900857
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65768
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-154	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.54789
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-3.11052
A1207	CCLE Cell Line Gene Expression Profiles	1.0	1.41097
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33413
central nervous system development	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989247
ficolin-1-rich granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71325
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65424
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23085
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9908
CRCGN015_MCF10A_48H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16849
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82302
AG-013608-5949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.53081
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828784
JVM-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41883
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52218
hsa-miR-3156-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044724
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986675
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.347959
CTV1DM	DepMap CRISPR Gene Dependency	1.0	5.95398
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41156
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15626
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-0.889894
HS766T	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19381
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7061
prochlorperazine-455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56988
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91856
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3141
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86312
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4089
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98526
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869629
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6026
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.30745
MM485	DepMap CRISPR Gene Dependency	1.0	2.90339
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48427
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21672
genistein-267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31209
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39122
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.091
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52265
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.35063
18318837-TableS2	GeneSigDB Published Gene Signatures	1.0	null
PMC4029184-1471-2407-13-585-S5.xlsx-All-eGFP_vs_EWS_WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
system development	GO Biological Process Annotations 2015	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989921
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7739
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22316
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.18958
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57304
bisacodyl-4616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ensheathing process	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
copper sulfate-500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60055
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93747
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28855
Charcot-Marie-Tooth disease type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7705
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.929332
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91562
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
hsa-miR-4691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
molt4	HPA Cell Line Gene Expression Profiles	1.0	0.96157
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	1.0	2.33905
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23035
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7371
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60064
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.27638
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0162
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.349
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0018
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58794
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10763
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22896
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69841
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43767
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2515
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-699-DACH2_DACH2	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null