association	dataset	threshold value	standardized value
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IA-94-MZ54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263923
GATA2	ChEA Transcription Factor Targets	1.0	null
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53972
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0274
BRD-K82105167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07868
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205811
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59076
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_6_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
Trachea-tracheal goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	1.51681
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72071
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43755
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23539
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3058
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-MXE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82002014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08098
diphenhydramine-1830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62295
BRD-K50117485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17559
FACT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139556
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03224
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.894892
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.61322
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0485
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.740468
triamterene-7307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A1207	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.51395
RHOXF2	Pathway Commons Protein-Protein Interactions	1.0	null
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSC 87877	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0706
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29312
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00773
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ginkgolide A-4121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942366
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
etofenamate-3989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nuclear membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K38791044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17285
DHX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39726
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41609
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47537
nadolol-4139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17814
A549_Regorafenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138545
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K95068765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61122
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17475
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5714
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21617
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.889
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44658
SOX11	ChEA Transcription Factor Targets	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912829
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35922
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.49694
ciclopirox-6677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-1080	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08615
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fusidic acid-6754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865146
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60981
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14557
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92201
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990894
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.695723
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2266
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53271
SPI1	ChEA Transcription Factor Targets	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948059
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00953
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78192025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30822
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.812518
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Childhood Leukemia	DisGeNET Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8433
CAD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
SNU475	DepMap CRISPR Gene Dependency	1.0	2.21187
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14972
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19436
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35476
A549_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121124
isoconazole-2218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937867
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18856772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25611
MXI1	ENCODE Transcription Factor Targets	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05981
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39151
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18898
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206883
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76035
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64979
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06971
BRD-K31297909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01363
BRD-K27172015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45032
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22108
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38636
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DOV13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K28351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53833
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
diflunisal-4794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14664
LY-294002-6945	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	4.02136
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.85836
D-392MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44879
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.9514
8903_TIAL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.71931
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.106
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15623
BRD-K98758203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27504
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836145
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63141
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83669
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.99239
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826918
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.740468
BRD-A02799884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67423
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47762
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
promazine-3752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69693
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1128
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
azlocillin-2727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22189
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03804
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93847
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84690141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15013
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15302
membrane	GO Cellular Component Annotations 2015	1.0	null
mebhydrolin-4211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43023353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5256
SMZ1	DepMap CRISPR Gene Dependency	1.0	7.74353
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sparteine-4568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61204
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
GSE146982_3_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_DN-Ensemble_gene_ID_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day4-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.53009
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcaine-4974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.857254
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5075
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13464
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18443
REST	ENCODE Transcription Factor Targets	1.0	null
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10609
HEYA8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33686
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.908543
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13286
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03291
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-HIF1_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.91614
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3185
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.60311
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
BRD-A91891312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00528
LB831-BLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26009
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26614
TCF7	ChEA Transcription Factor Targets	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918443
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	2.0673
Lung squamous cell carcinoma_LUSC_TCGA-56-A5DR-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.46519
BRD-K35413741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04004
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMS10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98096
PMC10281040-mmc1.pdf-6-ENSG00000118922_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95005
flecainide-3937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nuclear membrane	GO Cellular Component Annotations 2015	1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53842
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456668
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05709
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944929
dehydrocholic acid-5681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14978
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61354
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7808
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung adenocarcinoma_LUAD_TCGA-55-8302-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Notch signaling pathway	GO Biological Process Annotations 2025	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	4.11283
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.244
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.73448
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0517
A549_Tacedinaline_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133727
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08173
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33243
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.19194
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16446
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89853
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17108
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00894
spironolactone-2226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92374
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A673	Achilles Cell Line Gene Essentiality Profiles	1.0	1.21426
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38714
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.08957
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92586
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4237
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.45072
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0433
A549_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192609
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30674
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00397
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE194358,GSE194361_0_v_1_kdm5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80212510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2116
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROCK_INHIBITION_GDS3944_461_mouse_Forebrain astrocytes - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AsPC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.61084
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827694
Signaling by NOTCH1	Reactome Pathways 2014	1.0	null
BRD-K05057860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13792
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10121
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clofazimine-5642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12501
DLD1	BioGPS Cell Line Gene Expression Profiles	1.0	1.6618
PMC5088520__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48019220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94402
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97128
PMC9580020-tx2c00131_si_004.xlsx-Fig_5B_data-TABLE_S3_CORE_GENE_TARGETS_HSF1_KOVACS_ET_AL_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
amitriptyline-1823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
selegiline-4146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94714
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98163
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20073
BRD-K98639224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44445
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13343
5194442-6558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PSENEN	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32483
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966473
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996915
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985198
ML-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44478
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00746
PMC6895189__F4	PFOCR Pathway Figure Associations 2023	1.0	null
PHA-00816795-7076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34721
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.314
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88729
PMC3492937__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-137	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
SNCA_KO_GDS4153_527_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21154
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.578437
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34063
A549_Ramelteon_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127725
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33238
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47737
BRD-K44512951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2238
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851102
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10901
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985217
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.74902
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08925
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14615
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33509
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55412
BA-72-YP01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222126
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50119
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100541_FWM_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47083
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68119260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27029
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.920152
valproic acid-5582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140193
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371621
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33727
triamterene-1819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211996
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.971077
APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.11013
fusiform gyrus, left, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30741
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14699
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN013_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36241
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74222
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02524
Neuroepithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
BRD-K96440230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06557
A549_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129599
0173570-0000-4712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE141624_3_v_6_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.52797
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37052
A549_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201505
cefotetan-4116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82784
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873103
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00954
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51593
BCB000040-7488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metampicillin-5115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05599
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	2.05015
benzamil-2200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0375
PMC7332729__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
nicergoline-2220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911497
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43117
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-39-KG56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211599
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924673
BRD-K59542165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16505
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.912765
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82744
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203396
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1449
medial part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47737
BRD-K73442516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7661
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23949
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29772
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91885
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxolinic acid-5094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.22566
Lice infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
Prestwick-920-6497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07839
6-azathymine-2466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1051
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03544
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54689
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08925
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68842
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
CRCGN015_MCF10A_48H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.263
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900649
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437612
NCIH2126_LUNG	CCLE Cell Line Proteomics	1.0	2.55926
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenothrin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12463
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8193
valproic acid-1240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MDC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10828394-41698_2024_509_MOESM1_ESM.pdf-54-DPF1_DPF1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09118
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.727085
wortmannin-506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cytoplasmic periphery of the nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
A549_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141706
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72827
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30908
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29016
Teijin compound 1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
pentetic acid-3049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27927
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.573082
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19299
A549_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195699
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38115
UBE2D1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49872883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06257
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.48318
calycanthine-5744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.857066
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918446
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09162
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29971
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Recurrent Brain Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919555
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0597
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4124
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35681
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfamerazine-2181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76275
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79348
BRD-K81322049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13769
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44893
BRD-K90749965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15538
LN-428 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Enhanceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ascorbic acid-6306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51169
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8389
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.09511
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
A549_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196476
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01242
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.924537
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00325
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
bendroflumethiazide-3758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35744
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482333
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-2026-SM-4LVM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17196
OTUD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33906
PMC12695649-41588_2025_2389_MOESM2_ESM.xlsx-GATA6_RIME-_AsPC-1-Gene_Symbol_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58219783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13857
PMC12848082-41598_2025_33574_MOESM3_ESM.xlsx-MR-PRESSO_eQTL-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65729
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84208
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1933
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21747
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915214
A549_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149459
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03556
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76003
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866325
CAL33	CCLE Cell Line Gene Expression Profiles	1.0	3.36124
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042011
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21268
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.15314
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6634
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23314
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5817
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
aminocaproic acid-7258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61579
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43746
Hirata disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mismatch repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.87733
BRD-K20440082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1559
TNFSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543949
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.6454
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09515
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865495
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16045
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00161
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14922
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29539
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1267
BRD-K93543569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11051
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61507
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891081
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993109
JOPACA1	DepMap CRISPR Gene Dependency	1.0	5.92658
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST486	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68824
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321637
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973736
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02624
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
novobiocin-4569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1983
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44768
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54565
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
U251	BioGPS Cell Line Gene Expression Profiles	1.0	0.858708
LYL1	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51629
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06098
DC-84-CJ21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339464
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A7TX-01A-33R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45405
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.71243
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.588
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12286
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91079447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16843
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49087
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20419
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847225
BRD-K36697652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41396
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275322
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-KDM5B-Unnamed_6_KDM5B	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986555
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nipecotic acid-7296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PF-01378883-00-6405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920967
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27494
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545118
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.06152
Thymic Carcinoma_Thymus_GSE2501	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44611
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCAT_BILD_ET_AL	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86856
cyclic adenosine monophosphate-5108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHA-00816795-7072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.90135
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3955
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13708
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19916
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883647
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21047
PMC6190866__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6515
JNK_KO_GDS3001_531_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0358
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16531
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299463
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26622
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18009
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630873
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65025
NCIH1648	DepMap CRISPR Gene Dependency	1.0	3.49244
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31538
trimethoprim-4701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924369
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01251
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02381
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9287
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42
SW948	GDSC Cell Line Gene Expression Profiles	1.0	1.90877
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29702
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22332
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883105
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01334
K562_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168499
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230201
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A388	DepMap CRISPR Gene Dependency	1.0	6.9148
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43959
SFN	Pathway Commons Protein-Protein Interactions	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11762
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47827
CA46	CCLE Cell Line Gene CNV Profiles	1.0	2.10456
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936837
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.94714
A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.30041
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91934
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995199
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43049
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3966
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT116	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28527
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15525
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71298594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12233
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83805
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
CFPAC1	CCLE Cell Line Gene Expression Profiles	1.0	2.05753
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.255855
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81114
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hydroquinine-5789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949033
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68691
biological_process	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.3087
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.72446
etodolac-7246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2537
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26372
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05551
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Macrophage_Spleen_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
9592_UNC45A_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.680964
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54809
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217934
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9826
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.40962
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.459
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.62065
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82784
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27131
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.48251
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00979
BRD-A66369147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69775
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40553
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28768
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84086
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4076
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hexetidine-3318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29051
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5966
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
7893_SEM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.501255
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CEBPB_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM15_02_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58678
phthalylsulfathiazole-3371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chp212	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
dimethadione-5668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonal tumor with multilayered rosettes, C19MC-altered	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933049
A549_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169284
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042149
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-SNU-5	GDSC Cell Line Gene Expression Profiles	1.0	2.98956
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22096
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71326
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JAK2_druginhibition_168_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.03564
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378899
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51039
AC-58-RM63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467897
cation binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.904796
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00282
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
cyproterone-6806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.80775
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36957
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18865
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40503
PMC5088520__F1	PFOCR Pathway Figure Associations 2023	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FTC133	CCLE Cell Line Gene CNV Profiles	1.0	1.70654
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913664
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91914
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956348
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
EW-24	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55459
Mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4891
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.35926
BRD-K40265664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62125
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907105
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96395
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
brompheniramine-4131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
based	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
methazolamide-6268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Trachea-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	5.13909
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-2667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08306
skin	HPA Tissue Protein Expression Profiles	1.0	2.71915
Trachea-secretory cell	Tabula Sapiens Gene-Cell Associations	1.0	0.582249
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
throat	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.784553
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.28215
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
LN382	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.20525
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SHP77_LUNG	CCLE Cell Line Proteomics	1.0	2.63533
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.2743
SCC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Azacitidine_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131299
BRD-K02484256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23276
protein modification by small protein conjugation	GO Biological Process Annotations 2025	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07869
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Activated NOTCH1 Transmits Signal to the Nucleus	Reactome Pathways 2024	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79216
gfi1b_22201127_amulv_gof_mouse_gpl6246_gds4302	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.153625
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3772
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02621
pramocaine-6054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10539
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907074
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ergocalciferol-6746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14264
notch signaling pathway	GO Biological Process Annotations 2015	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
BRD-K61505971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46406
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127908
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28343
homosalate-3879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53816
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SE-81-RI20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.644931
Trachea-mucus secreting cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0296981
tanespimycin-5958	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85358
BRD-K85307083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04369
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51604
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57797
envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976923
sulfaphenazole-1673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36295
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33595
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01746
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56255
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15844
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45952
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00016
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02082
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26055
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
rent1_15448691_hela_lof_human_gpl8300_gds705	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.502328
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.97049
BRD-K75177817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17353
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22216
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2037
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9104
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885343
BRD-K52595962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10525
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU738	DepMap CRISPR Gene Dependency	1.0	2.57137
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.7683
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42132
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61237
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93847
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73463737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91214
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46056
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64167
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Disease	Reactome Pathways 2014	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.847151
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22845
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03361
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1327
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fluorocurarine-5741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SC-19220-7065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CE-15-DU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227821
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04193
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042186
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912492
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.38461
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Perturb_4274_KO_Cd22_SRP358571	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.474
CRCGN015_MCF10A.WT.HP_24H:D24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24554
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.371
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252904
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.619364
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04924
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52379519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11604
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26815
diethylstilbestrol-4547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62913
Staf	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05616
nuclear membrane	GO Cellular Component Annotations 2025	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837407
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860575
YD38	CCLE Cell Line Gene Expression Profiles	1.0	1.78375
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09348
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11001
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29016
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Notch signaling pathway	KEGG Pathways 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21487
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0706
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24945
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56825
COLO829_SKIN	CCLE Cell Line Proteomics	1.0	4.11592
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00655
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25573
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
furazolidone-4178	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984556
Clorgiline	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09661
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22228
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35512
PMC9844011-media-1.pdf-6-KLF12_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.63235
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06918
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48593
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04321
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K70361311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.261
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.068
disulfiram-2215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7332729__F5	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01242
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14264
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fipexide-5737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AH-23848-6890	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20989
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-2.16568
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13231
LS-513	GDSC Cell Line Gene Expression Profiles	1.0	2.0418
WWE domain	InterPro Predicted Protein Domain Annotations	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3613
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1036
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934139
oleandomycin-4615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878586
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.6017
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.805
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82122
azapropazone-7277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20891
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02679
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.21865
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30372674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0112
BRD-K99764436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20757
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28192
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69191
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20218
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3334
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
309_ANAPC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50596
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
metolazone-6292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20735575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16176
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996826
BRD-K84118789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30855
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155876
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21689
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1217
KELLY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45246
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239348
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45712
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60579
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.22487
RCOR1	ChEA Transcription Factor Targets	1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10740511__F5	PFOCR Pathway Figure Associations 2024	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.982
SLR26	DepMap CRISPR Gene Dependency	1.0	2.31901
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.69499
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51021
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840214
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2075
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99921
SOX17	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46025
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.4939
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46465
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.54179
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.3154
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17172
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835725
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09166
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871094
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89359
PMC2743399__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827582
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02338
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
T84	CCLE Cell Line Gene Expression Profiles	1.0	1.84572
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6007
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20394
PMC5379509__F8	PFOCR Pathway Figure Associations 2024	1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.88722
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72921
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27949
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908752
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC827	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.28235
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nuclear envelope and nucleocytoplasmic transport	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signaling by NOTCH1	Reactome Pathways 2024	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.25353
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91741
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CSL-Notch-Mastermind transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23721
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4703
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05385
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
A549_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183396
PMC10896338-media-3.xlsx-GSEQ_TF_AP1_UP_DOWN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923064
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95005
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35681
promazine-2173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41691
DUSP26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56904
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898248
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	3.52363
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.592
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844099
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
benfotiamine-3931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.08926
BRD-K39692099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78929
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44777
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7504
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36588
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277129
2.2.15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02393180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10971
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
beta-escin-2194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960332
A549_Avagacestat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185997
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52387
OC314	CCLE Cell Line Gene CNV Profiles	1.0	1.4536
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A549_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166794
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877674
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01227
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5459
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06306
BRD-K25363217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87144
Prestwick-860-4618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4269881__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24323
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_21-Supplementary_Table_21_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_TCGA_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831716
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41866
LN382	CCLE Cell Line Gene CNV Profiles	1.0	1.41192
BRD-K44236678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44446
substantia nigra compacta, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29016
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.14236
PMC10352428-18_2023_4859_MOESM6_ESM.pdf-1-CREB1_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.70576
protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.827496
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.42696
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973082
A549_Ivosidenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168623
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1018
CEBPZ_02_176	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60917
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.828643
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr7_76503080_A_G_b38	GTEx eQTL 2025	1.0	2.03818
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09089
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879669
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11801
BRD-K87161673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98359
RCC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874927
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874601
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
diclofenamide-3027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M07E	DepMap CRISPR Gene Dependency	1.0	2.22837
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255033
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K00509345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47489
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11542
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5126-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_E10_vs_LS_E10-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60974
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11899
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0523
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.10735
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1151
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42906
SRC_overexpression_277_GSE15161	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.76357
BRD-A35294449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5127
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10549
BRD-K45142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05553
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67977
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pimozide-7132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218768
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC2743399__F3	PFOCR Pathway Figure Associations 2023	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92662
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845507
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14182
Lung squamous cell carcinoma_LUSC_TCGA-21-A5DI-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37277666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51024
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205288
propranolol-6759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH446	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4134
BRD-K44536345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1792
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18397
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868213
Perturb_2814_KD_TRIM25_SRP267938	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.25494
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25055
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
Prestwick-983-6520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250989
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09427
icSARA deltaORF6_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.02849
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_DN-Gene_name_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56293
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13524
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18895
dihydrostreptomycin-5751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10093
BRD-K85359206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04763
A549_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153534
SKN	DepMap CRISPR Gene Dependency	1.0	2.55134
colo320dm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
L-methionine sulfoximine-4151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35681
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13238
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02246
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8331
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42693
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A459-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15142
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14264
furaltadone-3756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54842
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202056
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866426
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23878
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.65529
5955_OR4K1_ENST00000285600.4	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.55836
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75817
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.775596
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25118
corticosterone-4064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
progesterone-6646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41961
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-acetylmuramic acid-4406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3348
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893155
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456546
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85278
UBTF	ENCODE Transcription Factor Targets	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40858
A549_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133652
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473089
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68951
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38449
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873639
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38296
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
vitexin-4588	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77214
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
suprofen-4123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06098
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54079
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41664
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08925
r6 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02097
glipizide-6645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17289
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.86491
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.900524
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87008
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10499
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	Reactome Pathways 2014	1.0	null
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2998
crotamiton-4628	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
10min_PPase_inhibitors vs ctrl_Hepa1-6 (Mouse) [18846507]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895041
RGL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45350681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17495
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47737
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56773
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3411
LX-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.42674
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23672
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837775
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53567
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68637
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67345
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19983
neck	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01207
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.61918
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1794
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38801
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04108
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.05185
prednicarbate-5119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69558
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6502
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876997
Perturb_4590_KO_Ezh2/Runx1_SRP066416	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.81235
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865817
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88583
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36302
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366188
AD-55-WK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281857
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18257
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.43649
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7256
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26489
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4337
BRD-K58284640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47399
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17713
estradiol-5905	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
halcinonide-4703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.96278
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02378
PMC10913870-pr3c00632_si_001.pdf-118-ZNF592_ZNF592	Rummagene Transcription Factor Associations 2026	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409748
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
2233_DIS3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509492
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immunodeficiency 32B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_Motesanib Diphosphate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182506
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
A2780_OVARY	CCLE Cell Line Proteomics	1.0	2.13449
BRD-K87343552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08082
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92501
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09152
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3379
FOXM1	ENCODE Transcription Factor Targets	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.33661
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Activated NOTCH1 Transmits Signal to the Nucleus	Reactome Pathways 2014	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16478
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.867242
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8814143-41419_2022_4530_MOESM12_ESM.xlsx-up_ZNF32_vs_Vector-Unnamed_1_ZNF32	Rummagene Transcription Factor Associations 2026	1.0	null
2765_ETV5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.597264
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16484322-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.005
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944603
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tanespimycin-5578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A19829191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55488
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03699
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.34077
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.20899
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01518
midodrine-2087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857661
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05841
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0045
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NP8	DepMap CRISPR Gene Dependency	1.0	4.86306
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08973
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.96349
BRD-K47784262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31237
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
2236_DLAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.816147
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0493
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3245
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14563
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.978178
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51594
PMC10209342-mmc9.xlsx-UBE2D3_interactors-UBE2D3_interactors_used_for_Venn_Diagrams_from_MINT_STRING_UniProt_IntAct_BioGRID_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.914397
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.2036
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fluphenazine-2697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41314
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60716223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10566
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25386
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03279
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-SOX9_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31321
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1910_CSRNP3_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.768585
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29936
PMC2654975__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K21356734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10471
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27567
NCIH660	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50843
A549_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155817
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902031
KAT2A	ENCODE Transcription Factor Targets	1.0	null
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02384
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67805
flumequine-2276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10539
terazosin-5831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nuclear envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
USF1	ENCODE Transcription Factor Targets	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47089
LMO2	ChEA Transcription Factor Targets	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11271
metronidazole-4141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33597325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27502
sirolimus-2681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972393
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55112
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97569931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25279
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857144
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.55635
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3936
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97421379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19763
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.11352
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clidinium bromide-2734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967728
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.169
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855423
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02188
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17935615-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990114
BRD-K73275682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37772
A549_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143002
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934863
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837616
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PK-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08465
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832298
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38076
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925842
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495474
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00488
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130413
BRD-K37942718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07121
A549_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141778
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974964
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86216
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69395
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.871559
BRD-K96320811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2954
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
SW626	DepMap CRISPR Gene Dependency	1.0	2.21334
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37478
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00104
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30962012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2516
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229179
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947681
medial orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898642
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zinc finger, C3HC4 RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15124
BRD-K41307047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53921
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04129
BRD-K15775306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61954
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584501
Fatty Liver	CTD Gene-Disease Associations	1.0	1.07199
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20886
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155537
famprofazone-3928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15487
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4354
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.7004
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.64271
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990041
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07629
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.6978
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4232
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28066
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.920221
NCIH2110	DepMap CRISPR Gene Dependency	1.0	5.81341
Lung adenocarcinoma_LUAD_TCGA-62-A46Y-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23138
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80408
PMC11161608-41598_2024_64149_MOESM2_ESM.pdf-21-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02283
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964649
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.848796
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916309
18535662-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923204
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19982
ABL1_mutant_179_GSE45452	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59894
2537_EIF2B3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.641086
family	GeneRIF Biological Term Annotations	1.0	null
fulvestrant-5202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33747
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	1.53576
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58915
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3413
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71245
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28825
felbinac-3061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nordihydroguaiaretic acid-1223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59955428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13741
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43392
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYKNU	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05268
ARNT2	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64197
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56434
A549_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011585
functions	GeneRIF Biological Term Annotations	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16941
PHA-00745360-4559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-11-HV98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423218
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864381
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84488
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60793
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64893
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876229
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23092
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62809
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39633
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.96273
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
propranolol-3059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K91980109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07087
NCIH2444	CCLE Cell Line Gene Expression Profiles	1.0	2.32325
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42886
BRD-K31660953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7367
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82506
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JJN3	DepMap CRISPR Gene Dependency	1.0	8.91446
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12708839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7551
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2008
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7472
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860233
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841496
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4446
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85572169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05382
thiethylperazine-6154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924836
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916662
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51279
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary Malignant Neoplasm Of Brain	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09096
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044547
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65933652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04483
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11373
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHEMBL1597046	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4313
BRD-K85604751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33978
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01557
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DTX3	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835457
COLO320_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.21244
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.55833
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65301
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29649
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945896
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14283
5181_MPZ_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.605688
azacyclonol-6298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1262
Lafora disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07859
CRCGN016_MCF10A.TP53.M_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74368
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846956
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RT112	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00664
Necrosis	CTD Gene-Disease Associations	1.0	1.32667
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1387
tacrine-2633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372247
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10622
Ibutilide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.47734
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59522
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64331
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.942972
nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.668975
binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2235
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633318
T3M5	DepMap CRISPR Gene Dependency	1.0	2.64225
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14264
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34217
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04581
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tetroquinone-4078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20236423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04088
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K66748326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13091
A549_Belinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.00999848
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844937
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.47127
nitrofurantoin-4697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.8108
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943097
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988949
HPCAL4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pou5f1_16518401_mesc_lof_mouse_gpl1261_gds1824	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.225901
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI-8866	GDSC Cell Line Gene Expression Profiles	1.0	1.58297
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2545
BRD-K50053371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3812
PMC9314667-Table_1.xlsx-Regulons-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09728
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07722
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958014
SW48_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.21244
Dinoflagellate hypocone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854828
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K52932858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15746
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865301
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839233
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96641838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53704
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826856
KYSE30	CCLE Cell Line Gene Expression Profiles	1.0	1.46774
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	1.94771
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.840799
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA-420 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3048
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880053
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901014
Perturb_14803_KD_Gm26917_SRP340980	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.7104
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4045
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74203
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62505
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83337
fludroxycortide-4702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apigenin-4401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABP	MotifMap Predicted Transcription Factor Targets	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAY-10397-7071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_A-366_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172453
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0766
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39896
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903551
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93900188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57577
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reported	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.39093
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04704
BRD-K06834318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01291
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88898
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41154
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982464
BRD-K95569142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26986
pre-B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01368
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.801699
RSV-A2_24Hour-B6.129PF1_J_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.95774
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30844
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47813
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
WM88	DepMap CRISPR Gene Dependency	1.0	3.79357
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3561
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79327
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913392
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0952
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3943
lower basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15854
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.718153
GSE223008_6_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29135120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36488
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1245
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04779
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980788
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2222
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03355
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.12574
diazoxide-2214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
furaltadone-3932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94806
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	3.04691
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17511
iopamidol-2732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47413
cefadroxil-4161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287879
A549_Alisertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130076
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10357
dihydroergocristine-7275	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52767
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CAKI2_KIDNEY	CCLE Cell Line Proteomics	1.0	2.35297
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74091
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48344
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00935
NCI-H747	GDSC Cell Line Gene Expression Profiles	1.0	1.77317
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53304
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0263
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17211
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830969
spironolactone-2064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34063
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00538
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
mantle zone of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02066
Atrophic muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02621
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-CON_VS_LPS_252-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22411
tranexamic acid-2085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3511
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pthirus pubis infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.124
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2596
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74101
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.39963
Hypertrophy	CTD Gene-Disease Associations	1.0	1.04314
Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6187_PDLIM2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-A06232236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67872
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32544
BRD-K93615384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36022
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322203
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901318
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58399
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9563
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28497
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51285
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924836
BRD-K68083867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14222
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3937
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16446
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.367
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278896
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13515
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41717
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11181634-13098_2024_1365_MOESM1_ESM.xlsx-DEGs-MSC_DEGs_in_the_diabetic_microenvironment_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.31434
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03495
BRD-A14842104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19225
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06098
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
fludrocortisone-3785	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.892463
PMC2654975__F1	PFOCR Pathway Figure Associations 2024	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.03965
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73033
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12842
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06016
Dapagliflozin_A549	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0148438
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46616
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dtx	GeneRIF Biological Term Annotations	1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883178
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43017
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75106
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11739
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19984
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67285
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34005
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55581
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04349
A549_Pirarubicin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140206
SARS-CoV_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80472
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0163
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94949
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964587
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25625
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17402
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.238
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936707
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11331
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994147
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02743
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26767874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22398
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
9962_ZBED2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.860746
CRCGN016_MCF10A.TP53.M_24H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20525
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53132
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
dizocilpine-5746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NMCG1	CCLE Cell Line Gene CNV Profiles	1.0	1.44578
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62425
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.78009
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28503
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K22865069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19743
BRD-K49409947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76632
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966473
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844766
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22792
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49696
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888454
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632781
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.762833
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00356
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Supratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.394
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868328
fusidic acid-2647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854236
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.625374
diethylstilbestrol-4369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU213	CCLE Cell Line Gene Expression Profiles	1.0	1.47643
OCIM2	DepMap CRISPR Gene Dependency	1.0	4.12941
Colonic cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143164
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.95661
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64777
BRD-K08504955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10668
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64944
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02679
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9166
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.567781
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1063
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75699
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469098
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824317
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.81396
Dapiprazole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34177
GSE200320_3_v_2_mfge8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	0.926328
GSE148066,GSE157787_2_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02448
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46785
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4384
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52512
BRD-A14484404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0189
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
clindamycin-2219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.084336
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60847
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482491
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.847861
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K14970242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0604
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37895
BRD-K30937829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82493
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05981
protein ubiquitination	GO Biological Process Annotations 2015	1.0	null
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69659
GSE235066_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53029
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.826365
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
thiamazole-3815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34537
PBX3	ENCODE Transcription Factor Targets	1.0	null
RBPMS	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.867036
ND-07-WN37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284553
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16528
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15124
CRCGN011_HEPG2_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69535
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7027
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01242
MSTO-211H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.213448
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14443
BRD-K55562948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13052
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611237
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60677
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890893
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09006
A549_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201666
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.63927
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34461
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	1.16729
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.866759
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06877
PANC0403	CCLE Cell Line Gene Expression Profiles	1.0	1.45814
primidone-3402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01242
Nucleoplasmic periphery of the nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
BRD-K89805341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23272
MAC2A	DepMap CRISPR Gene Dependency	1.0	2.14227
Neck	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875253
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04235
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34063
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
3-hydroxy-DL-kynurenine-4681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15312
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243958
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K76518272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13936
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28948
NOTCH1	Pathway Commons Protein-Protein Interactions	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12575
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24772
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dtx1	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879816
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46202
BRD-K44445002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46044
BRD-K14763154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12403
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06801
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.78938
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6124
HOUAI	DepMap CRISPR Gene Dependency	1.0	4.40059
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20782
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13334
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04105
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2647
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
econazole-2396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18291
BRD-K00970182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36303
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14201
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Prestwick-664-4737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33136
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07401
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919058
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37729
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.781101
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04993
prostate	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
BRD-K54089081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64181
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15615
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85362541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32227
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38775
NB4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.96576
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfamethoxazole-2296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alcuronium chloride-4409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
debrisoquine-6688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17704
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56054222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10815
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7307
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-SE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989219
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40968
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82822
sulfacetamide-1695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01577
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.09023
CAL51_BREAST	CCLE Cell Line Proteomics	1.0	2.17929
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04171
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89376690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80911
cyclopenthiazide-7325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21918
A549_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174148
APH1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
midecamycin-6745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51737
ofloxacin-4696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579042
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991698
sirolimus-5975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844021
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.46377
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3208
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5NE-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8481_KD_DAP5_SRP073613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.3987
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6071
Tizanidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
GW 501516	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-x_TFEB_KO_con_VS_WT_con_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34837
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.058
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12184
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
buflomedil-1338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48862
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900024
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924429
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07187
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26903
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.965847
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887115
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36215
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879753
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51025
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12316
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915621
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838548
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25668
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4395-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU99	DepMap CRISPR Gene Dependency	1.0	2.22002
HOP62	BioGPS Cell Line Gene Expression Profiles	1.0	0.960624
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FE-82-WB22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215115
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13664
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47737
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76049
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.536492
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9477
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26138
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08162
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNCA_KO_GDS4153_443_mouse_Striatum - 6 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60106
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978412
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.85585
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27979
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06517
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16126
BRD-K65813214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14419
A549_Lapatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162072
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943815
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03384
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34718
MET_knockout_260_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28824
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11294
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.7151
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98236
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40935
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rosiglitazone-6950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12226398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12549
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06328
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09997
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
BB30-HNC	GDSC Cell Line Gene Expression Profiles	1.0	1.77545
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K11030235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80429
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.938101
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878815
CRCGN014_HEPG2_3H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4794
dimethadione-4607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8491
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NI-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.89204
SU8686	CCLE Cell Line Gene Expression Profiles	1.0	1.40309
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968373
BRD-K36134264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49893
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cefotaxime-2072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE124410_2_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5749
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
bergenin-2726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671149
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47445
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18111
BRD-K47541706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01512
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48403
BRD-K32854540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30429
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58718
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
NS-398-6892	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.548939
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52272
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74484
ES1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74738
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Byssus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.95844
SH4	DepMap CRISPR Gene Dependency	1.0	2.59502
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53762
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199081_0_v_1_insr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1024
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Kleptomania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.44619
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82807
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37026
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292777
PMC10281040-mmc1.pdf-6-KLF12_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29649
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
selegiline-4065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15386
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03281
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06354
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14759
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01951
KKU100	DepMap CRISPR Gene Dependency	1.0	2.76384
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14471
BRD-K50977435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15485
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.917891
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854613
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
prasterone-6673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963197
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97372
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.45658
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30334
TGBC18TKB	DepMap CRISPR Gene Dependency	1.0	2.49133
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34793
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.13521
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13486
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24121
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79298
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02763
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986969
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
Labial palp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30851
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206918
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411643
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07159
Perturb_9487_OE_Fi3_SRP273336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.00614
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53029
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50725
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.634
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2274
their	GeneRIF Biological Term Annotations	1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06368
equilin-4659	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72666
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07537
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04086
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917483
tetraethylenepentamine-498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
Notch Signaling Pathway(Mus musculus)	WikiPathways Pathways 2014	1.0	null
valproic acid-348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN011_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4314
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09626
fusiform gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13626
gramine-4118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54903703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18734
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61133
Nutritional deficiency, NEC_Skeletal Myocyte_GSE1776	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.67087
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03781
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Unnamed_9_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16364953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48881
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11472
SARS-dORF6_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.32137
BRD-K84975143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37843
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23865
selfubiquitination	GeneRIF Biological Term Annotations	1.0	null
BRD-K01716842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24958
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76307
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37047
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01009153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00443
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68015
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64076
lanatoside C-4328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939435
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.676341
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00533
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912793
palmatine-2795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21469
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373161
chr7_76582769_A_G_b38	GTEx eQTL 2025	1.0	1.09581
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48666
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96205
basal plate of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66034
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cherubism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
gabapentin-2731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15286
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72936
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74463
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916437
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15759
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16725
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1388
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63919
Clopidogrel_A549	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0117125
chlorzoxazone-1416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	3.9117
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27973
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835068
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41913
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90639
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435951
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70933
BRD-K78889331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02992
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.36356
carbachol-6742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37245
MOLM13	DepMap CRISPR Gene Dependency	1.0	2.2099
ciclacillin-4358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thyroid gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
luteolin-6658	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.85999
INIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35599
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14775
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36679
GSE148066,GSE157787_9_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35637
tretinoin-1211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15341
BRD-K96449536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21706
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44628
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981775
OE-78-XD40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274444
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18441
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41654
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.72833
TP63	ChEA Transcription Factor Targets	1.0	null
wortmannin-6959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315969
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30907
BRD-K44224150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36597
Gastrointestinal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K47783463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6182
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5225
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954826
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22075
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08178
TC71	Achilles Cell Line Gene Essentiality Profiles	1.0	1.7573
mutlalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.06347
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91624805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51201
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12966
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840268
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K92468187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6587
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916571
BRD-K11517399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01755
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890035
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49275
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6839
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850213
Epristeride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ramifenazone-2534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bromopride-2182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864505
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900048
PMC12624014-41419_2025_7799_MOESM1_ESM.pdf-36-DOT1L_DOT1L	Rummagene Transcription Factor Associations 2026	1.0	null
IRS2_KO_GDS1219_304_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83869
KDM5B	ENCODE Transcription Factor Targets	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.094
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16974
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K47370004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76928
PECAPJ41CLONED2	CCLE Cell Line Gene Expression Profiles	1.0	1.3691
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Type 2 diabetes mellitus_Renal Tissue_GSE642	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.38058
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.532343
PMC11542230-12985_2024_2548_MOESM4_ESM.xlsx-MR_results-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2824
NCALD	Pathway Commons Protein-Protein Interactions	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441998
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63696
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
ALKBH4	Pathway Commons Protein-Protein Interactions	1.0	null
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25395
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SFN	Hub Proteins Protein-Protein Interactions	1.0	null
SK-N-FI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56747
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981533
ethionamide-2495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC2891586__F3	PFOCR Pathway Figure Associations 2024	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839275
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90157
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63379
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19381
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08634
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41939
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07833
Urinary bladder squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973365
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15124
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01324
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1163
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.09822
A549_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152215
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	3.90693
BRD-K61283064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0534
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51153
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31666
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830448
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54605
NCIH1693_LUNG	CCLE Cell Line Proteomics	1.0	3.59376
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Keratosis follicularis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13393
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
UBQLN4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4697333__F3	PFOCR Pathway Figure Associations 2024	1.0	null
racecadotril-5755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05637
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8645_TACC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.576689
Cerebrum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20989
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35936
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878484
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4653
A549_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125606
17823238-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39198
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09461
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.975441
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN2-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_screened_in_VENN1_with_E3s_interacting_with_EZH2_or_MYC_from_the_UbiBrowser_v2_database_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11812
IGROV-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.91517
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79597
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21416
U343	CCLE Cell Line Gene CNV Profiles	1.0	1.34177
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917119
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75331
protein modification process	GO Biological Process Annotations 2015	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56017
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99077411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3703
Coffin-Siris syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.872389
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
RERFLCMS_LUNG	CCLE Cell Line Proteomics	1.0	3.80411
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10072
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3254
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SHI1	DepMap CRISPR Gene Dependency	1.0	4.80505
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04264
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61511
Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0309
CRCGN015_MCF10A.TP53.M_24H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0887
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47372
SW480_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.9555
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23419
Lung adenocarcinoma_LUAD_TCGA-49-6745-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE84678,GSE93902_1_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89253
BRD-K60509482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32579
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855423
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67136
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A89983325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41514
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12915
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3431
PLSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11181
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20262
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03216
cefotaxime-2235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54624
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24661
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00529
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.827695
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66196
PMC6895189__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71028
sirolimus-2702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hel	HPA Cell Line Gene Expression Profiles	-1.0	-0.977606
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43392
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537635
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01226
APH1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6980-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K19672435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19104
LS180	CCLE Cell Line Gene CNV Profiles	-1.0	-2.54041
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899474
BRD-K40378743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03657
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.06406
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34133
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
nuclear envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
sulfamethoxypyridazine-4733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23058
bemegride-6668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06058
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPG21	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847313
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09865
STOCK1N-35215-6380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28399
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.989966
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.954181
BRD-K52582315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46638
rifampicin-2487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5871764__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902029
novobiocin-499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922227
HGC-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75964
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.21903
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584396
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	3.42627
SU8686	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56592061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09409
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84698
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05124
A549_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132642
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966573
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876997
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3437
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043628
BRD-K44864058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14446
NCI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56987
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974783
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379155
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895148
mefloquine-2210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85883
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942574
PMC9844011-media-1.pdf-6-ENSG00000118922_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01207
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952518
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.167572
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0706
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911929
OC316	CCLE Cell Line Gene CNV Profiles	1.0	1.52546
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902881
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00795
SB-202190-6887	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10243
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
ligases	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877646
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268999
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1359
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pararubral nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0706
mycophenolic acid-4137	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03575
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24671
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041581
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95410891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33042
PMC10740511__F4	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84019
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13161
metrifonate-1675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRF8-21731497-J774-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.595
basal reticular formation of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12313
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09348
6261_PGM2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.58348
cell part	GO Cellular Component Annotations 2015	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3625
gossypol-3740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39111
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50255
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.7914
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70427
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34837
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37514
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01242
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAK1_druginhibition_166_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.03564
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31686
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16446
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412901
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00953
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147489
BRD-K54036439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54797
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845855
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAS-012416453-6880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08925
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868598
monocyte, dendritic cell, and NK cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07496
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03855
PMC8424196__F3	PFOCR Pathway Figure Associations 2024	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894808
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48476
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332288
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3651
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89675
pentolonium-4699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158605
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5616
cobalt chloride-454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44341877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43617
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01362
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59273
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55141
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2D4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19518
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tongue	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04287
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00769
GSE169590_6_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54396
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57379
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05832
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3419
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4925
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841831
PMC7940623-41467_2021_21725_MOESM11_ESM.xlsx-Extended_data_table_9_regulons-JUN_extended_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.532163
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A549_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00858067
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73907
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34626
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3573
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15339
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04324
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16253
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966863
RELA	ChEA Transcription Factor Targets	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.8445
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52834
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35352
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01215
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
QB-99-OU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228886
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12475
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02102
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60702
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881002
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.999229
PMC5871764__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08387
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.037
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SR-95531-4236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19427
Nuclear membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30485
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87326
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24622
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
methoxamine-2488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19532
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13095
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24561
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591269
metyrapone-4606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37151
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75251
BRD-K43388152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36936
BRD-K22725588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39881
acetylsalicylic acid-2664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14112_OE_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.38805
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304976
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-A21524347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57894
A549_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155591
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47688
GD-96-AK08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.434089
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
edrophonium chloride-6655	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3492937__F5	PFOCR Pathway Figure Associations 2024	1.0	null
cimetidine-4063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07673
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17349
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995825
BRD-K66838902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12246
8827_TEX15_ENST00000256246.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.65305
CTCF	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatic stellate cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59285
BRD-K38972344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63107
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01388
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42844
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83693
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025579
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.37341
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995076
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.88647
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.736084
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896537
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89178
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.518
PMC6365498__F8	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85174
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239416
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28887
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.66426
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VSNL1	Pathway Commons Protein-Protein Interactions	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797535
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
TT2609C02	DepMap CRISPR Gene Dependency	1.0	2.89889
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	Reactome Pathways 2014	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850405
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874684
SRC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K80296876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2241
PMC9580020-tx2c00131_si_003.xlsx-Fig_5A_data-HSF1_KOVAC_same_dataset_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.165231
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935301
lung	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393396
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03355
NR2F2	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01577
betaxolol-4608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01575
SARS-BatSRBD_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95129
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00637
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53111
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.27477
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46002
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941137
stomach_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.860171
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50416
IRF8-21731497-J774-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60647
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7025
BRD-K98133478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18148
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59608
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21175
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886222
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896749
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23622
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4191
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12823
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LY-294002-6175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16446
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39506
BRD-K07826724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55175
lateral part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34063
signal transduction	GO Biological Process Annotations 2015	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16431
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65032
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11215
Signaling by NOTCH	Reactome Pathways 2014	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dicloxacillin-6666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219287
KA-51-CQ55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639347
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58719
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5836
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1794
hsa-miR-4767	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
A549_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170189
UPCISCC074	DepMap CRISPR Gene Dependency	1.0	4.50047
PMC6042247-NIHMS966841-supplement-Sup_Table_2.xlsx-Gene_Sets-ISL1_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30581
Signaling by NOTCH1 PEST Domain Mutants in Cancer	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18436
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8795
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464679
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.38218
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0648
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23273
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832128
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14546
BRD-K48235506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25885
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.745518
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA_02_39	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60822
BRD-K44858727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07082
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26138
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49091
SCaBER cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826188
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322549
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DC-45-WU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29924
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956199
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1479
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.341
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.62641
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943063
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8624
PMC2891586__F3	PFOCR Pathway Figure Associations 2023	1.0	null
nadolol-3359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00363
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31097
chr7_76451162_A_G_b38	GTEx eQTL 2025	1.0	6.78477
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23403
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50545
piperacillin-4320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57498440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37517
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system embryonal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966168
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.4931
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944426
Benign Neoplasm Of Brain, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26403
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869808
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82091
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38563
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19775
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16435
cyclopentolate-5734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
fulvestrant-7534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ondansetron-6153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cefamandole-4718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83072
trichostatin A-3058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16446
BRD-K70379342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37601
LM4_M2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949249
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45381
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6182
ELF1	ENCODE Transcription Factor Targets	1.0	null
ampicillin-1530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K01212001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08708
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4346
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928167
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34069
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	2.05712
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09348
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65767
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46669
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54809
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140246
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65522
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69187
CTCFL	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39108
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.25373
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.11576
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281903
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09968
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37296
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93472147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52557
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56037
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999462
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXW7 Mutants and NOTCH1 in Cancer	Reactome Pathways 2014	1.0	null
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.71993
dexamethasone-5797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08297
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0213	CCLE Cell Line Gene Expression Profiles	1.0	2.4667
Signal Transduction	Reactome Pathways 2014	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21681
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96675
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.38641
HEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87679
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949916
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0009
SKMM2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23402
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04977
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830565
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr7_76445802_C_T_b38	GTEx eQTL 2025	1.0	2.00054
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50971
physostigmine-5749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_5039_KD_Smarca4_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.43154
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03502
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immunodeficiency 32A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60819
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDGF_ERK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3367
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924719
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.00093
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mycophenolic acid-4019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.04195
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846818
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1635
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60672
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20018
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11423211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54954
Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
santonin-4531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2396
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07804
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.87148
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40587
mafenide-2287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3144
yohimbine-6777	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64073
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	1.73253
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.963146
dtx2	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZD-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.01625
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30625
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.073
GSE231799_2_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70378808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41173
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0843
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64038
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
inferior temporal gyrus, left, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886925
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05586
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
NCIH2029	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46297
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12721
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81286
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.34997
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.54728
erythromycin-6729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20159
notch signaling pathway	KEGG Pathways	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RB1_KD_GSE50532_641_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RFX6	Pathway Commons Protein-Protein Interactions	1.0	null
gossypol-2202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909828
parbendazole-3799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94676
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
AA-10-VR76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235654
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69072
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04753
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14264
A-CA-04-2009(H1N1)_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04825
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15343
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33186
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	1.06071
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855423
BRD-K34747076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09578
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36038
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
betonicine-4767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77791
0198306-0000-7069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0769
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961945
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chlorambucil-4345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2184
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3803
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63237
capan2	HPA Cell Line Gene Expression Profiles	1.0	2.03682
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07965
BRD-K53770426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4706
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.6581
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38589
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14353
vincamine-4341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5379509__F8	PFOCR Pathway Figure Associations 2023	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45812
rosiglitazone-4457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968712
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
procainamide-4602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57043
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymph	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Tumor, Primary	DisGeNET Gene-Disease Associations	1.0	null
clorgiline-6659	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845573
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.912237
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957338
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58
BRD-K37285826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36766
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63124
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20815
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32201
etoposide-6681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE247084,GSE247087_0_v_1_cdyl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7444
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62P-01A-32R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59076
Signaling by NOTCH	Reactome Pathways 2024	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY-294002-5937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26226
BC-74-QN56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262551
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-47-MH68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588615
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	2.13383
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876229
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.964105
18356575-Table1a	GeneSigDB Published Gene Signatures	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450126
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986906
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15077
MEWO_SKIN	CCLE Cell Line Proteomics	1.0	4.05814
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36181
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulconazole-6652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-ddORF6_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.03015
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64655
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12845
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909632
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18549
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung-respiratory goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	1.74875
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27892
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.97833
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23577
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15334
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68755
chr7_76541239_T_C_b38	GTEx eQTL 2025	1.0	1.55386
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.725982
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0822
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-SOX2-Members_of_the_SOX2_regulon_as_identified_by_SCENIC_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07363
BRD-K60030763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18423
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.921847
PANC0504	DepMap CRISPR Gene Dependency	1.0	3.65679
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973615
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904777
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.22915
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-0.961923
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200734
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BHY	CCLE Cell Line Gene Expression Profiles	1.0	1.904
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70175
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52436508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12949
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28081
skin	HPA Tissue Gene Expression Profiles	1.0	1.32071
BRD-K35953312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71397
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42295
HEP3B217_LIVER	CCLE Cell Line Proteomics	1.0	2.53838
ligase activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43773
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11005
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
terfenadine-2227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29977
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23231
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34476
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16462
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42581
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3936
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892663
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56084
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84785
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06116
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270349
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19291
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
GSK3B_KD_GDS4305_183_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.85413
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02577
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966523
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74295
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0031
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20837
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2297
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr7_76495842_T_C_b38	GTEx eQTL 2025	1.0	1.76335
metabolic process	GO Biological Process Annotations 2015	1.0	null
BRSK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966994
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.75392
atractyloside-3695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46409
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58279
medial group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56397
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31665
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0847
methylbenzethonium chloride-3943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
HPCAL1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07975
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haloperidol-2663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08058
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3683
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
astemizole-2211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isocarboxazid-3684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-860-3040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34063
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	2.30989
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30444
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94334
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61052
BRD-K56349799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05975
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32587
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05781
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941697
josamycin-5692	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89793
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28373
nicotinic acid-3381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20989
BRD-K90155857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21089
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966473
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.16186
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BFTC909	CCLE Cell Line Gene CNV Profiles	-1.0	-1.31982
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	1.76574
chlorpropamide-6291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EC-71-PH39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29214
BRD-K73376409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05285
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66128
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348705
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.956355
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.70546
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857813
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827939
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909324
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16355
Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.3387
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.29405
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902071
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.11277
dienestrol-5727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21288
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359612
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3073
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28817
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01426
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Notch signaling pathway	GO Biological Process Annotations 2023	1.0	null
BRD-K11420482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00938
377_AP2M1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.667337
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0997
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6725
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19008
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.93467
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6468
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.61331
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966473
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08569
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07289
Lung squamous cell carcinoma_LUSC_TCGA-85-A50M-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.126
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908245
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08925
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22954
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21784
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5178-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42179
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50862
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
epivincamine-4500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45904306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04099
PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53832
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00618
PMC8120022-CTM2-11-e420-s006.xlsx-Sheet1-Table_S1_786_altered_genes_involved_in_cancer-related_pathway_in_TMPRSS2_ERG_fusion-positive_prostate_cancer_Genes_involed_in_multiple_pathways_are_duplicated_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998096
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18549
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853967
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211906
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25145
zimeldine-4609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4531
BRD-K36575696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09403
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.852785
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20681
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04314
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6020-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL54	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52805
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84501
BRD-K37780492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08323
SW1783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.63341
E2F6	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A02927672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52871
beta-escin-4364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tetracycline-5757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12502
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-3943	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.67945
NCIH2110_LUNG	CCLE Cell Line Proteomics	1.0	2.12871
BRD-K73681382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76197
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
FD-15-HD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313008
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57357721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91334
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3498
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73779
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73037
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.39105
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859213
capsaicin-4612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996034
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58434
A549_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124988
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32347
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18111
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4367
Lung squamous cell carcinoma_LUSC_TCGA-85-A53L-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A90289676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62832
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32139
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38931
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DTX1	Pathway Commons Protein-Protein Interactions	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50671
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8877
JIYOYEP-2003	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tanespimycin-6926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
m1 (rostral) midbrain tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234153
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53681
BRD-K07565511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34011
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836631
YY1	ENCODE Transcription Factor Targets	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864646
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74101
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41735
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28088
GSE148066,GSE157787_3_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12331601-Table2.xlsx-KD_vs_CON-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HL-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0852
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837291
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41493
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31793
triamcinolone-2241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
baclofen-1536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP2_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18549
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.48486
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.969
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00565
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876835
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33061098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90226
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50052
doxazosin-6642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.65485
NCIH441	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.65907
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80923834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00568
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.53838
CRCGN015_MCF10A.TP53.M_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07495
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94397
suramin sodium-7529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81419
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41289
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66034
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865333
A549_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175696
BRD-K38350115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42296
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924629
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leflunomide-2539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853967
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6561916__F4	PFOCR Pathway Figure Associations 2023	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11074
Lung adenocarcinoma_LUAD_TCGA-86-6562-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ceforanide-6751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	4.27631
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903675
Thyroid gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3912
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2175
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12146
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06016
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838811
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211693
ES7	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6462
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839776
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26658
BRD-K95153342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19583
BRD-K27823380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05427
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.49834
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08038
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94279
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835143
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0407
BRD-K70042405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42899
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00744
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37843
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26731
Hypotrichosis 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.281
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.17427
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12378
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944581
cyanocobalamin-4572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02524
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.942894
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82807
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1482
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1969
BRD-A05883068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01552
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.949497
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.117
vitexin-4413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Liver Diseases	CTD Gene-Disease Associations	1.0	1.03752
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH650_LUNG	CCLE Cell Line Proteomics	1.0	8.16117
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	1.16033
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280748
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09823
BRD-K66432757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48177
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14277
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
NOMO1	CCLE Cell Line Gene CNV Profiles	1.0	2.70466
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20806
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09796
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-257	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43331
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69396
A549_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143163
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33055
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9237
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03196
dtx3	GeneRIF Biological Term Annotations	1.0	null
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00558
Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86025005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30796
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88477
CRCGN008_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3069
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.563
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40467
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16867
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.204
DD-23-ZC57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209808
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911044
CNS cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	HPA Tissue Protein Expression Profiles	-1.0	-1.43459
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885473
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3941
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1633
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13853
AR-A014418-7070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
helveticoside-4327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10034
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47737
BRD-K41538715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52585
lasalocid-6639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43392
CRCGN017_MCF10A.WT.HP_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57095
cyanocobalamin-4395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934728
PMC4269881__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23936
K562_Capecitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156255
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3674
nefopam-4752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847101
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26337
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66945
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29702
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20989
HEK 293T	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.62002
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0112
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927436
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18799
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HGC27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56474
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.551827
ketanserin-6649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32528
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962018
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16804
BRD-K22679163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33185
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6506
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.799
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.585218
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05413
SNU324	CCLE Cell Line Gene Expression Profiles	1.0	2.38063
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48084
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478601
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06439
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06782
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18549
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tolbutamide-3804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6881
dna repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1319
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12326
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233923
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32526
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68323
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL11A	ENCODE Transcription Factor Targets	1.0	null
haloperidol-1244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A2058	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56513
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.955044
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.82618
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.98836
iocetamic acid-4425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57511
melatonin-6293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38927
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853967
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59583
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63236
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22316
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34645
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849771
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71775851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08502
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676553
(4-Chlorobenzyl)pyridine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
acetylsalicylic acid-4428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flumetasone-4734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6573_KO_Gls/Mpc2_SRP338093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.3663
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44304623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46515
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01239
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852404
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L1_NFE2L1	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58945
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70779
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876229
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29016
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.24046
drofenine-2714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF8	ChEA Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17553
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48239
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52352
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13853
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carteolol-4176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09234
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_5_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.24753
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06573
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05658
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30537
estradiol-5955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07649
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A549_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134121
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1635
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042694
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39506
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bacampicillin-4417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182774
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11097
BRD-K90863245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5207
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bicuculline-4574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
bepridil-4613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCS1	Pathway Commons Protein-Protein Interactions	1.0	null
oxaprozin-3794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34314
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869795
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
scoulerine-5111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829545
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71874
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11532
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1548
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86408
BRD-K21759602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68486
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
canrenoic acid-2228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.69023
BRD-K25185158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35674
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843396
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51516
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39388
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00172
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
HT29	Achilles Cell Line Gene Essentiality Profiles	1.0	1.55844
BRD-K02610196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06304
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10751
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64165
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50856
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Signaling by NOTCH1 HD Domain Mutants in Cancer	Reactome Pathways 2014	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74101
Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02524
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876229
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922316
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
fluvastatin-3032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11271
Embryonal tumor with multilayered rosettes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
heart	GeneRIF Biological Term Annotations	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83354
CRCGN009_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26743
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08171
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21383
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64762
Signaling by NOTCH1 in Cancer	Reactome Pathways 2014	1.0	null
NCIH1975_LUNG	CCLE Cell Line Proteomics	1.0	3.36875
BRD-K26603007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22695
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.72327
A549_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122424
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2392
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-63-SV27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326335
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25694
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.84489
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13442
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41656340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57237
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
doxepin-6337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95863
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20738
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09338
NR3C1	ENCODE Transcription Factor Targets	1.0	null
HUH7_LIVER	CCLE Cell Line Proteomics	1.0	2.35297
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82122
TCF12	ENCODE Transcription Factor Targets	1.0	null
Hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.913
EB-09-OC36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214298
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1988
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03564
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63127
dilazep-4688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06791
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934812
TAL1	ChEA Transcription Factor Targets	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913583
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MKN45	DepMap CRISPR Gene Dependency	1.0	4.29087
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.630233
Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isopropamide iodide-2720	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4697333__F3	PFOCR Pathway Figure Associations 2023	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12313
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6262
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24778
SEM	Achilles Cell Line Gene Essentiality Profiles	1.0	1.58668
fluocinonide-3757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39707
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924121
chr7_76545947_G_A_b38	GTEx eQTL 2025	1.0	1.13154
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31889
DOHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mianserin-2231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02719847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39951
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43475
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14804
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21149
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42912
GABPA	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25991
citiolone-3755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99145
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14264
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32406588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00516
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02613
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2139
hexetidine-6319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K40646662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27927
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00559
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47645
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01313
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855423
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973736
KMBC2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06034
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71542
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.72539
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14397
SP1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45785
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32935
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6561916__F4	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.74095
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.607
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842729
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47626
2974_FARSB_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.584001
methotrexate-6654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
milrinone-7210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148066,GSE157787_3_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HC-76-HU27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242709
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K81293413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01835
CRCGN017_MCF10A.WT.HP_24H:M10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65455
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02302
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
Protein phosphatase type 2A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.637
fludroxycortide-6039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50894381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07741
MD MB231	BioGPS Cell Line Gene Expression Profiles	1.0	1.27536
A549_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163179
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913015
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oxybuprocaine-1476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K14258088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91776
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.617
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
4-Methylhistamine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930926
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6456
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06798
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05257
tyloxapol-4611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior frontal gyrus, opercular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930492
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730417
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923307
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485129
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06472
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.808785
BRD-K78432272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17299
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K58977196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32398
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66507
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1022
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.538577
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3138
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58101
flunisolide-4303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53029
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A03898562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20131
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859193
sclc21h	HPA Cell Line Gene Expression Profiles	-1.0	-1.44985
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arbutin_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0118071
dihydroergotamine-2244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269199
PMC6365498__F8	PFOCR Pathway Figure Associations 2023	1.0	null
MD-92-LN15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226837
encoding	GeneRIF Biological Term Annotations	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76980944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44052
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206046
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919782
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22192
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979181
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878548
sirolimus-5927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33549
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414796
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.44282
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542474
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12917
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853043
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42018
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871823
meclofenamic acid-2291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76951
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26332
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42527
Prestwick-642-4594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7463
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24337
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11306
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHSA8926	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334158
Blonanserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05212
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_1_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
thioproperazine-2236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EPZ004777	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K91854399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06765
adiphenine-1831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10478
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9794
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80475
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59865704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08148
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tetroquinone-4159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56156
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37449
Gliclazide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
BRD-K30071505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85165
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78764
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66436
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245561
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.848344
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68946
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Ki16425_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013298
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53029
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859085
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877093
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38684
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31273
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53703060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22694
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266693
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20218
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Throat	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26111
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.13251
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	3.97658
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256313
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57917
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964757
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47762
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202133
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
SEC22A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74101
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72951
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18608
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35162
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02679
Pons, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74101
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.29755
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08433
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16065
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.6177
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225146
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27896
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1635
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fenoprofen-4736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49018
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21047
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6931
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35681
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91615
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36638
6862_PSMC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570154
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tubastatin A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
bretylium tosilate-3394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517604
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910395
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10347
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282294
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15061
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498502
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gentamicin-2082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39199
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
SISO	DepMap CRISPR Gene Dependency	1.0	2.38597
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239932
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
sodium phenylbutyrate-363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5614
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4782
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4395
fluocinonide-3933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.793871
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87999
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871646
NCIH23	DepMap CRISPR Gene Dependency	1.0	3.48024
gallamine triethiodide-2221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69252983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21807
ion binding	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6981-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14476597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4181
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44151
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.56793
pretectal tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66034
MTOR_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K75252192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76107
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55436
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10243
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39594
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56317
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39293
JHU029	DepMap CRISPR Gene Dependency	1.0	5.1342
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829523
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40858
oxantel-6738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12751
JUND	ENCODE Transcription Factor Targets	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1311
BRD-K17514980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95823
GSE168070_3_v_2_erbb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.88722
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08388
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4593
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
esculin-3052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02333
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A85028244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56266
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2671
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53029
hsa-miR-20a-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03236
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837925
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.082
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558364
A549_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145821
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56376
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09657
canadine-2818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.991866
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9227
UMUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.48937
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86872
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64329997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01993
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26138
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41217
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.927527
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW1990	GDSC Cell Line Gene Expression Profiles	1.0	1.78996
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25338
PMC7387553-41467_2020_17477_MOESM4_ESM.xlsx-B_LPS-stimulated_myeloid_cells-Cis-eQTLs_in_LPS-stimulated_myeloid_cells_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear envelope adjacent to nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868858
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03579
SKNBE2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60798
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-2.38821
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71838
ERG	ChEA Transcription Factor Targets	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81237
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908752
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28117
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37393
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
capacity	GeneRIF Biological Term Annotations	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841847
BRD-K63921431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30808
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09389
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82441
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04222
sulindac-1815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE241875_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98156994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16035
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241125
bisoprolol-6748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fluvastatin-3370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14959
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64469421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37395
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0486
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824894
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27836
D-423MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32539
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
Cauda equina syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7466
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19155
Perturb_10437_Mut_Chek1_SRP299085	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.86372
clobetasol-4497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gabexate-4804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35693854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35331
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827783
nordihydroguaiaretic acid-4447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
6534_POLR1B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500176
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32562
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03406
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94392
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05212
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08831
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43846
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21355
AG-012559-6889	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.92254
HS675T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61108
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05631
BRD-K79688948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16903
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18025
BRD-K60166659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29338
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847729
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10899
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL62	DepMap CRISPR Gene Dependency	1.0	2.78463
HLC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36787
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.19413
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
a549	HPA Cell Line Gene Expression Profiles	1.0	1.56177
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.266
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92223
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843802
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84974041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10336
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26695
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21776
BRD-K11502669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15642
22RV1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32405
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0406
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825844
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15304
tretinoin-5571	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976237
BRD-K00191683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4373
Cancer of prostate_Prostate_GSE1413	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.71833
BRD-K47511177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85731
carbamazepine-5093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016196
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41398
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934254
BRD-K00046588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2899
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44102
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
0198306-0000-7064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSS131R	DepMap CRISPR Gene Dependency	1.0	3.78859
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K43495666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18286
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1040	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36439
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23423
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.78119
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943809
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209148
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88636226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59841
BRD-K02362691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71704
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29522
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13054
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864464
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43392
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826079
Notch Signaling Pathway(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13269
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3997
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02862
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964674
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871605
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62366931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02852
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74269
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27486
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.54999
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08908
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54816
Digestive cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pioglitazone-5925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120113
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.1607
sulfafurazole-4661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347632
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847432
fluvoxamine-4114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
propofol-3386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC10862883__F5	PFOCR Pathway Figure Associations 2024	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11176
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07659
BRD-K94344234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39139
PMC6190866__F6	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2052	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922243
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19683
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32383
acetylsalicylsalicylic acid-2223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6904
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11208
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43794
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4ENIF1	Pathway Commons Protein-Protein Interactions	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633255
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12034
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
IHH4	DepMap CRISPR Gene Dependency	1.0	2.94056
adenosine phosphate-6760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15442
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868642
PHA-00767505E-6591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149943_1_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BPH1	DepMap CRISPR Gene Dependency	1.0	3.851
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36898
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451532
metanephrine-6734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trifluoperazine-2684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbinoxamine-2725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28815
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2191
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15056
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21202
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26686
A549_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141074
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.22988
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15007
protein modification by small protein conjugation	GO Biological Process Annotations 2015	1.0	null
bbap	GeneRIF Biological Term Annotations	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.832487
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975449
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81492
POU2F2	ENCODE Transcription Factor Targets	1.0	null
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.845153
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17779
16498405-TableS10	GeneSigDB Published Gene Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9105
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5813
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.564
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	3.15299
MKN45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LY-294002-2676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.76664
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867637
CBX3	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847179
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
superficial mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32139
A549_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149531
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23021
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6648_KD_IQGAP2_SRP398102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343517
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44175
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5818
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26709
fluoxetine-6757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A44046220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20113
cefmetazole-2524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19227646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41567
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_5_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48146
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.75957
BRD-K64770897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10651
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04073
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
ampyrone-2249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3193
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CA-63-LW25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339757
PSEN2	Pathway Commons Protein-Protein Interactions	1.0	null
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49134
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
COLO679_SKIN	CCLE Cell Line Proteomics	1.0	5.0919
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5335
nuclear membrane	GO Cellular Component Annotations 2023	1.0	null
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54434
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17389
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898772
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.8249
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871204
2613_EMC3_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509411
diloxanide-3062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269993
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890048
WWE domain, subgroup	InterPro Predicted Protein Domain Annotations	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9423
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H510A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44275
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27938
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3286
SW1417	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29028
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870474
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.885646
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10351
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54606
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214107
NCIH1184	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76382
tobramycin-2481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13965
A549_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167647
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82784
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBQLN4	Hub Proteins Protein-Protein Interactions	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943482
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932809
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357696
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null