association	dataset	threshold value	standardized value
A549_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159067
Jeune thoracic dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.826
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47931
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96023
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168504
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162642
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0243928
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119267
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17013
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.838
Intraflagellar transport proteins binding to dynein	WikiPathways Pathways 2024	1.0	null
GSE224311_3_v_0_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Effects of MFN2 mutation	WikiPathways Pathways 2024	1.0	null
Midbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.415
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Ellagic acid_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146918
PMC4243378-13059_2014_494_MOESM1_ESM.xlsx-S1_6_Gene_sets_CIITA_BIs-Monocytes_IFN_CIITA_not_RFX5_RFX5	Rummagene Transcription Factor Associations 2026	1.0	null
MSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21306
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7666
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10862
MCF7_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017257
MCF7_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189822
5732_NOL10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.534105
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135848
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7411
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8148
GSE198165,GSE198166_9_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7926
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07452
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.301
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.445
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEK-AD293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
A549_PF-573228_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145817
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10351
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07994
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250298
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.488
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27602
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
6460_PLRG1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.58184
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7451
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliopathies	WikiPathways Pathways 2024	1.0	null
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10654
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19016
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.607
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9979
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
6625_PPIE_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.524894
MCF7_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188704
GSE71100_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39297
MCF7_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134127
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.459
A549_Azacitidine_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131197
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05936
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.895
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166317_2_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.288
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.904
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8817
GSE206516,GSE206518_1_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8228_SNRPD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.50488
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28268
MCF7_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138538
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133075
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.488
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ciliary plasm	GO Cellular Component Annotations 2025	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5514
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
MCF7_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135135
MCF7_WP1066_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159731
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10434
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-203-ZNF79_ZNF79	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213991
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus lentiformis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.081
9837_WDR70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.501713
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
MCF7_Bisindolylmaleimide IX_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202513
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.32
1943_CTR9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.592252
MCF7_Tanespimycin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00911664
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_73_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22515
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41917
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30622
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2329
MCF7_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168839
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04035
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.701582
GSE116580_0_v_1_smug1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26927
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7205
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Epothilone A_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212404
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.212
MCF7_Epothilone A_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160571
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129284
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17016
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10127
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6044369-oncotarget-09-29162-s002.xlsx-TableS5A_MYC_target_FPKM-Table_S5A_FPKM_values_of_MYC_target_genes_Related_to_Figure_5A_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
MCF7_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010851
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3429
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27527
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.384
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.449
7275_RGS14_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.545242
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amniotic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27094
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
A549_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150161
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
Axial length	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
A549_SRT3025 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149409
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3251
PMC5932012-41467_2018_4180_MOESM18_ESM.xlsx-Table_19-GSEA_Gene_lists-Zuber_Myb_KD_DN_HUMAN_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
608_ATF5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.601666
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.361
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136215
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06909
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150779
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3715
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35733
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164905
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4785
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018343
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-FOXM1_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.383
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.075
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56986
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0107277
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cilium Assembly	Reactome Pathways 2024	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21671
A549_Bosutinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110056
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06472
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215581
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169899
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19875
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-MYC-target_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44356
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
K562_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204863
RPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20653
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04713
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56512
MCF7_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176189
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26289
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
5016_MFAP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.50077
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.607
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22712
2545_EIF3B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.574171
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8537
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
K562_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221259
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7942
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7804
9975_ZBTB17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.573454
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LM6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
MCF7_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015674
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84447
Olfactory lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.099
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35231
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.504089
6629_PPIL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.576833
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4147934-1755-8794-7-50-S3.xlsx-gene-set_table-MYC_New_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16946
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134063
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26833
PIAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19751
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0818
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78972
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9938
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.812
GSE134375_0_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142549
Bardet Biedl syndrome	WikiPathways Pathways 2024	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26087
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.653
MCF7_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141174
MCF7_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189911
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-2_E2F1-Gene_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09072
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255988_2_v_0_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane bounded cell projection cytoplasm	GO Cellular Component Annotations 2025	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1451
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fibre tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.415
MCF7_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157964
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
PMC11519602-41418_2024_1333_MOESM3_ESM.pdf-40-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15127
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Bosutinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00958132
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58827
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7665
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
8232_SNRPF_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.569649
mr89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
6032_PAF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.585525
A549_PCI-34051_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120532
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4167
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47282
K562_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159987
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cd86 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.6
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152626
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188458_2_v_3_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02104
Corn ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5325343-oncotarget-07-63003-s002.xlsx-Supplementary_Table_1-Supplementary_Table_1_Genes_upregulated_by_EWS-FLI1_in_the_Gordon_et_al_data_set_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60946
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6517_POLD3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.611019
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-10-DNMT1_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
MTHFD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69258
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.381
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
1943_CTR9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.518215
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-652-ENSG00000196152_ZNF79	Rummagene Transcription Factor Associations 2026	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0354
MCF7_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191321
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163166
MCF7_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226026
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0525
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dynein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171845_4_v_3_ccne1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.793
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1972_CWC22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.542636
MCF7_Sodium Phenylbutyrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155099
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160001
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00941
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76536
MCF7_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149683
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5MK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02698
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17615
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1496
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_13_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14872
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
A549_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177999
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Flagella connector	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
5810_NRDE2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.670646
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.329
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
Cytoplasmic dynein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8925
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4799
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
WDR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24509
1410_CDC73_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.533469
MCF7_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141682
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
6351_PIK3C2A_ENST00000265970.7	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.570765
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.301
MCF7_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014789
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26345
A549_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167507
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-4_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-73-ENSG00000101544_ADNP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01172
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
A549_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174687
PMC4243378-13059_2014_494_MOESM1_ESM.xlsx-S1_6_Gene_sets_CIITA_BIs-All_CIITA_not_RFX5_RFX5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NLS-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.449
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17199
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181933
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216467
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04249
GSE193993_4_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9463
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146984
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38793
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F2_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210079
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2887
PMC12273355-12882_2025_4346_MOESM1_ESM.docx-0-SOX17_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.746
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08897
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1149
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19424
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.1549
MCF7_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00903144
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9945
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4145
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182778
MCF7_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142574
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168207
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78887
8669_TAF7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.545954
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81637
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pons	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.164
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6522222-NIHMS977514-supplement-Sup_Table_15.xlsx-WT4_WT5-Unnamed_0_POU6F2	Rummagene Transcription Factor Associations 2026	1.0	null
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05276
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spine apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21165
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11485
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142536
GSE135350_2_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.912
MCF7_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130334
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43167
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.893
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0297
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05028
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09893
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_435_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.06429
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_IOX2_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013727
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.284
MCF7_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115823
PMC10290283-biol-2022-0622-sm3.pdf-244-ZNF787_ZNF787	Rummagene Transcription Factor Associations 2026	1.0	null
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5903
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3902
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.49
MCF7_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136506
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nuclear lumen	GO Cellular Component Annotations 2025	1.0	null
MCF7_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145408
4940_MED18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.777257
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
MCF7_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011317
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7695
5900_NUP62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.625271
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.068
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02183
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Daphnetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153887
MCF7_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123363
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NES-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0286906
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
8426_SRRT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.571843
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1272
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4668
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Signal recognition particle, endoplasmic reticulum targeting	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.292
GSE209533_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510504
MCF7_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155391
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.472
1971_CWC15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.58178
MCF7_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172631
PMC6522222-NIHMS977514-supplement-Sup_Table_15.xlsx-WT3_WT5-Unnamed_0_POU6F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31161
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.85561
MCF7_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0256441
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.94774
4695_LSM5_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.569473
A549_GSK J1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138449
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.144
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.445
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F8_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128269
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F7_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.563
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149471
MCF7_Luminespib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110913
3598_GTSF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.532143
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.677
PMC4872073-supp_gkv1528_nar-02930-x-2015-File004.xlsx-Table_S2A-CREB1_Target_Genes_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
cilium organization	GO Biological Process Annotations 2025	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14644
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
RPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0833
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral peduncle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.415
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5392
Organelle biogenesis and maintenance	Reactome Pathways 2024	1.0	null
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1339
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45701
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35403
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05744
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8068
MCF7_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128865
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.329
MCF7_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172581
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015868
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-ZNF274_OE_vs_EGFP_CTR_DE-gene_ZNF274	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175864
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1525
PMC7817097-abb9149_Table_S2.xlsx-293T-TET2-FLAG-Table_S2_Mass_spectrometry_results_for_endogenous_SMCHD1-FLAG_in_ES_cells_and_TET2-FLAG_in_293T_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.329
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03129
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168298
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130368
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.678
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8975
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6613
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210255
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06948
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32189
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.888
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.658
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204336
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary landscape	WikiPathways Pathways 2024	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135395
GSE133213_4_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.712
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014786
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16652
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.556744
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9756
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5188
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.655
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11651170-pt4c00533_si_002.pdf-67-SIX5_SIX5	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186595
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3434
GSE195568_2_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.245
em3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.792
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10876637-41531_2024_653_MOESM1_ESM.pdf-30-CXXC4-AS1_CXXC4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Short-rib thoracic dysplasia	ClinVar Gene-Phenotype Associations 2025	1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00126
PMC5013636-ncomms12601-s5.xlsx-SP1-Groups_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
interleukin-20 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
PMC4909989-ncomms11840-s3.xlsx-Sheet1-The_overlapped_genes_regulated_by_YAP_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
10090_ZFP42_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.583776
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.365
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00491
MCF7_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129355
MCF7_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0245444
cilium assembly	GO Biological Process Annotations 2025	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47356
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.55117
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012942
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
2120_DDX41_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.676535
MCF7_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139822
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134883
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_23_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.657747
MCF7_Hesperadin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00955731
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02475
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	207.698
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60291
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132768
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151090_5_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39019
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161177
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_WT-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35171
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210091
K562_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167336
GSE144453,GSE144454_1_v_0_tfdp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166588
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10011
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
MCF7_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227442
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Wing bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6023
4696_LSM6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.542398
K562_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158062
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160442,GSE160444_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150931
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
MCF7_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128921
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7166_RBM25_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.620791
MCF7_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147419
Pelvis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
6720_PRDM10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.673368
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
7585_RTF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.51779
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5286
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02057
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Centrosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MCF7_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213025
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20573
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
6801_PRPF4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.645464
PMC7825356-8844261.f3.docx-269-ZNF418_ZNF418	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018109
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37568
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tubastatin A HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201457
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61137
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	174.334
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.574
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary basal body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.637
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.545716
1408_CDC5L_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.561777
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.887
GSE154577_6_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175643
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.698
GSE188458_2_v_0_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
8252_SNX29_ENST00000306030.3,ENST00000323433.4	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.51083
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135404
MCF7_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124007
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44408
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6947
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.433
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9534_UBL5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.559533
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145277
intraciliary retrograde transport	GO Biological Process Annotations 2025	1.0	null
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GLI-SUFU complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6585
MCF7_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013481
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2433
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
3q29 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56606
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5249
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44211
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4769
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7186_RBMX2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.527385
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157782
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44182
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-T_B-pT3_B_shared_histone_ZNF135	Rummagene Transcription Factor Associations 2026	1.0	null
6797_PRPF3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.512257
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178596
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525781
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3304
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09929
1843_CPSF4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.550402
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.49
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1957
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic dynein complex	GO Cellular Component Annotations 2025	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.551454
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164811
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94659
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cilium	GO Cellular Component Annotations 2025	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
MCF7_GSK-LSD1 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014885
MCF7_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192829
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160281
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3222
A549_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142303
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.787
organelle assembly	GO Biological Process Annotations 2025	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_UNC0379_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143653
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-E2F4_5_targets_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
Neural progenitor cell_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
MCF7_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151483
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
10136_ZMAT2_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.518345
MCF7_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228995
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182594
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1575
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.827
MCF7_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181775
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122007
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165463
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
K562_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166779
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0104907
MCF7_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146362
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7940623-41467_2021_21725_MOESM11_ESM.xlsx-Extended_data_table_9_regulons-ATF3_extended_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_2_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
13_AARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.513735
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112558
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60136
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137639
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-73-ADNP2_ADNP2	Rummagene Transcription Factor Associations 2026	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1023
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513719
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.383
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48222
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.086
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7036
Intraflagellar transport	Reactome Pathways 2024	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_5_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227518_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.814702
A549_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122633
PMC3060339-emmm0003-0089-SD1.pdf-26-ENSG00000104447_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176449
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
A549_TMP195_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124246
K562_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017377
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.59
PMC11461876-42003_2024_6975_MOESM5_ESM.xlsx-Supplementary_Data_3-Supplementary_Data_3_Differentially_Expressed_Genes_HSE_THP1_UV_Vs_HSE_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.887
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.61767
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
b63	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Centriole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Ki8751_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177811
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141533
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9516
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17527
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lip epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192186
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82616
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204215
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-E2F6_OE_vs_EGFP_CTR_DE-gene_E2F6	Rummagene Transcription Factor Associations 2026	1.0	null
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02143
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.436
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140703
MCF7_AT9283_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117042
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.77426
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0377
MCF7_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011744
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-359_common_elements_in_HIF1_peaks_and_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6917500-elife-47110-supp1.xlsx-Table_I-Table_I_Differential_gene_expression_of_G0_G1-phase_invasion_cells_and_the_cells_treated_with_DMSO_SKI-73_and_SKI-73N_SKI	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
141_ADAT3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.562322
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.099
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.747337
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Olfactory bulb	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.099
PMC11347378-41375_2024_2357_MOESM4_ESM.xlsx-Fig_7A_S8A_public_RNA-seq_DEGs-TFDP1_KO_HAP_cells_Human_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22059
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ciliary tip	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06181
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00473
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4566
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4099
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123453
Periciliary membrane compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212303
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amnion epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
MCF7_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132067
9815_WDR34_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.800065
Genes related to primary cilium development based on CRISPR 	WikiPathways Pathways 2024	1.0	null
GSE198165,GSE198166_0_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2203_DHX15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.614134
PMC7203476-Table_3.XLSX-Sheet1-GV_MI_overlap_227_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.273
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41457
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11629
nucleolus	GO Cellular Component Annotations 2025	1.0	null
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.32
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0463
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
8680_TANGO6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.514842
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24202
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55988
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100588
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.572302
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
MCF7_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126652
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7478_RPL7L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.58919
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
K562_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018403
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
8426_SRRT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.576181
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224278
MCF7_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166496
PMC9669968-Table_1.xlsx-Sheet1-Supplementary_Table_1_List_of_genes_for_the_three_AR_signatures_generated_by_the_study_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
5430_NAA38_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.518197
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30723
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52144
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP3K11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65186
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.463
GSE126463_1_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156429
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_GSK J1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142809
Globus pallidus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.081
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.078
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95791
8184_SMN2_ENST00000380743.4	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.530404
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
1268_CCDC174_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.654186
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119693
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131645
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147864
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29781
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.93907
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.959
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0243675
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
2203_DHX15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.57047
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.676579
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02988
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28702
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49343
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
MCF7_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153323
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04862
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3955
MCF7_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135106
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05443
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4357
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183021
GSE80537_3_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06933
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85655
GSE176305_0_v_3_rotenone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5392
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2157
Eating disorders (purging via substances)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149243
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9189
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.63994
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07171
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.512553
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09071
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207327
nuclear membrane	GO Cellular Component Annotations 2025	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166878
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194533