association	dataset	threshold value	standardized value
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dense core granule	GO Cellular Component Annotations 2025	1.0	null
Agammaglobulinemia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
positive regulation of corticotropin-releasing hormone secretion	GO Biological Process Annotations 2025	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.205
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9927
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4536
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7439
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9545
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12853
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3773
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8989
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110268_0_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52049
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3892
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
neuropeptide activity	GO Molecular Function Annotations 2025	1.0	null
Esophageal carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5379
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
positive regulation of corticosterone secretion	GO Biological Process Annotations 2025	1.0	null
CNE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
ANAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20518
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.33136
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6219
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7106
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136591_0_v_1_akap11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HME1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
increased circulating cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2148
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56996
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
u	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09374
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06412
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14921
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fibroblast_Artery_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
CTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65857
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
SGC-7901 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29178
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5717
Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
Fibroblast_Blood vessel_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.51
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9565
PMC5322933-pone.0172430.s013.xls-Immune_MSC_Single_Basal_vs_MSC-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0763
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
PMC10362029-41598_2023_35401_MOESM3_ESM.pdf-1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
PMC9399107-41467_2022_32627_MOESM6_ESM.xlsx-20_T-cell_subsets-gene_name_CD8_C1_LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45814
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00334
Esophageal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22292
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5099
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12021929-Table1.docx-0-E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0563
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9286
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59432
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Chordoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.202
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9773
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66569
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06272
central nervous system development	GO Biological Process Annotations 2025	1.0	null
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.647
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83045
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8878
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9869
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33586
GTEx Lung 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.09869
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9885
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04902
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06719
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04285
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4455
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
g8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
PMC5322933-pone.0172430.s013.xls-HG_MSC_Single_Basal_vs_MSC_AD_B-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.51
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5778
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39994
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.701
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1482
Nasopharyngeal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21321
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2929
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2313
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16459
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12244
PMC8499523__F6	PFOCR Pathway Figure Associations 2024	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7372
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40749
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53139
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65554
Middle ear cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04498
GSE173262_2_v_5_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80476
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-506-ZEB2_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Tertiary granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51869
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21968
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57488
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.693
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6157
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09825
GSE191105_0_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08387
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.989
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85709
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142684_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7056
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56455
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3704
negative regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07678
Auditory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
NE-4C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.041
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04103
PMC12480273-12672_2025_3611_MOESM1_ESM.xlsx-csgene-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.73
Stomach carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.947
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12689
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12779
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Substance dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.51
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.37614
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12036091-jcav16p2321s1.pdf-31-ZNF208_ZNF208	Rummagene Transcription Factor Associations 2026	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.205
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6427
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16748
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5485
positive regulation of glucocorticoid secretion	GO Biological Process Annotations 2025	1.0	null
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14081
Lipopolysaccharide receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6683
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomach cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3319
PMC10758738-BLOODA_ADV-2023-010385-mmc2.xlsx-SuppTable_S6_Classifier_params-TLX1_classifier_TLX1	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.149
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
GER cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3071
chr2_106065334_TG_T_b38	GTEx eQTL 2025	1.0	4.6323
SUNE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66851
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60627
regulation of corticosterone secretion	GO Biological Process Annotations 2025	1.0	null
peptide hormone secretion	GO Biological Process Annotations 2025	1.0	null
ITPKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11619
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10939
Nasopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18802
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14332
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56503
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0392
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18439
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1504
Pharyngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12120721-ADVS-12-2411752-s001.xlsx-Data_S15-Data_S15_DEGs_in_ESR1_SMC_ecotypes_Invaginate_env_vs_UM_niche_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15256
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06222
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5743
Amoeboid microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8255
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3951
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80869
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esophageal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.156
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9121
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69662
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.0303
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03308
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.041
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67471
Ependymal cell_Hypothalamus_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9198
Specific granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89821
positive regulation of corticotropin secretion	GO Biological Process Annotations 2025	1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04691
UBTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16084
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.60695
PMC12120721-ADVS-12-2411752-s001.xlsx-Data_S23-Data_S23_DEGs_between_ESR1_SMC_ecotypes_and_DES_SMC_ecotypes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.096
Esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3378
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.15612
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08916
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Neuroepithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2686
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Middle ear carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1307
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1835
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48019
CWR22-Rv1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.735
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55128
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86754
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7098
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.848
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7182
PMC11588066-pnas.2410331121.sapp.pdf-138-IRF3_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9747
decreased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
GTEx Breast 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	4.58594
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12193
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2696
short tibia	IMPC Knockout Mouse Phenotypes	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Up-regulated-Supplementary_Table_S2_Up-reguated_genes_expression_in_MESP1_positive_cells_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09818
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8804
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0927
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26805
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6932
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
MED18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21042
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81864
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60519
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3074
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_9_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nasopharynx epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
NHDF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18981
GSE221004_1_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
chr2_106066249_A_G_b38	GTEx eQTL 2025	1.0	3.57924
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36207
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
Ciliated cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10248
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19082
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51073
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8287
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2727
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4465
Uroepithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.80587
Venous endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
decreased mean corpuscular hemoglobin concentration	IMPC Knockout Mouse Phenotypes	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
PCDHB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15049
Esophageal cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0002
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.607
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.233
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51838
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2578
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27145
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_8_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
decreased large unstained cell number	IMPC Knockout Mouse Phenotypes	1.0	null
PMC6344081-elife-40364-supp5.xlsx-PLZF_peaks_H3K27Ac_unchanged-Unnamed_10_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	5.36217
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of peptide hormone secretion	GO Biological Process Annotations 2025	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15155
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62746
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7837
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.077
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.077
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal eye anterior chamber depth	IMPC Knockout Mouse Phenotypes	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47548
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.664
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2901
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
EC-9706 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27336
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4706
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Middle ear squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.978
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5612
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1097
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05719
vasopressin secretion	GO Biological Process Annotations 2025	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43131
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Tympanum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07365
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of corticotropin secretion	GO Biological Process Annotations 2025	1.0	null
PMC8321895-41375_2020_779_MOESM4_ESM.xlsx-marker_genes-TLX1_TLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01543
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31151
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0629
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12549544-mmc2.xlsx-AA_D28_VS_D42-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04973
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7275
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08915
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52383
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
GSE142684_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08019
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28801
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.873
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2947
negative regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1724
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6274
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6294
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22397
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4938
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08046
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8982
Sperm head plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09924
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12177
regulation of corticotropin-releasing hormone secretion	GO Biological Process Annotations 2025	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29494
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7478
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9681
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.6261
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92408
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09647
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hormone activity	GO Molecular Function Annotations 2025	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2275
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38785
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05781
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.276
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47423
Laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
PMC12848082-41598_2025_33574_MOESM3_ESM.xlsx-MR-PRESSO_pQTL-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Muscle 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	6.15815
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE261563_2_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55612
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74981
GSE96991,GSE97117_5_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
substance-related disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.51
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3185
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12307501-Table1.xlsx-ST12-Supplementary_Table_12_Results_of_the_comparisons_of_AP_expression_levels_between_different_biological_age_groups_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
BT-483 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.662
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7196
Renal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9595
Nucleus taeniae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18701
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5429
mt3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
increased body length	IMPC Knockout Mouse Phenotypes	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Matrifibrocyte_Heart_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0066
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12512047-Table2.pdf-30-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
GSE115363_2_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.041
PMC12122724-41467_2025_60028_MOESM6_ESM.xls-Supplementary_Table_4_Marker_g-Supplementary_Table_4_Marker_genes_of_six_TPIT_tumor_subtypes_TBX19	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02102
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44617
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218060_5_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.907
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04668
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.99425
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20827
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7595190-41598_2020_75453_MOESM6_ESM.xlsx-MLL_EFS_groups_DEGs-Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22807
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42357
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8961
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0195
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.776359
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1984
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57535
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14277
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07529
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06328
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.041
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1071
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08306
Notochordal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89303
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7766
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10426
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
Middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
anaphase-promoting complex-dependent catabolic process	GO Biological Process Annotations 2025	1.0	null
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
TXNDC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19281
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
Drug dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.51
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neuritic plaques or cerebral amyloid angiopathy (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2393
Ear cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65513
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.4058
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1961
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.769
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0533
GSE96991,GSE97117_5_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0406
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Renal pyramid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6397
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0898
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
nervous system development	GO Biological Process Annotations 2025	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0607
shortened QRS complex duration	IMPC Knockout Mouse Phenotypes	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180631_1_v_0_yap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	3.32238
Tongue carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.259
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5322933-pone.0172430.s013.xls-Oncopath_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
Secondary progressive multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
PMC10985171-Table_1.xlsx-Table_S3-Table_S3_IPF_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08551
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1243
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20635
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4051
GSE127970_2_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.023
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.67379
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0101
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2867
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41998
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27239
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE250518_0_v_2_trpm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cyclin D1-CDK4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
Protein N-acetylglucosaminyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
Systolic blood pressure in sickle cell anemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
PMC11568168-41598_2024_79607_MOESM3_ESM.xls-11-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0617
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5562
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Pharyngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1701
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	10.9121
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9
PMC4521181-oncsis201520x8.pdf-112-SPDEF_SPDEF	Rummagene Transcription Factor Associations 2026	1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17354
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31335
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24963
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2709
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20431
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24811
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13638
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157904_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8775
Immunodeficiency 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3868
Esophageal squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
neuropeptide signaling pathway	GO Biological Process Annotations 2025	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.031
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
Otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1619
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.513
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.01
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	0.764555
Astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25441
castration-resistant prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50101
Esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35224
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45165
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.669
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22477
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67096
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05176
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Laryngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
NPC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
IL6ST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16186
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55364
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_36_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30106
SMMC-7721 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
GSE125153_2_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44839
Presbyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.205
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1591
GTEx SmallIntestine 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	5.44051
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0733
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.489
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3703
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-13_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7798030__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC7200799-41467_2020_15997_MOESM8_ESM.xlsx-MasterRegulators_FOXO3-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6485
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.136
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3371
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8247
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11518
Stomach disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1351
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6781
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03481
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
GSE180951_2_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
neuropeptide hormone activity	GO Molecular Function Annotations 2025	1.0	null
HUC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.114
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.951
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
PMC5322933-pone.0172430.s013.xls-Pathways_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0989
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39014
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6709
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.451
GSE165647_6_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165548_2_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09219
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.659
Tongue cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32932
Papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.205
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23425
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8075
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15364
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0116
Neuritic plaques or neurofibrillary tangles (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383