association	dataset	threshold value	standardized value
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07112
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bone structure disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cpt1b	GeneRIF Biological Term Annotations	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pdk4	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.37189
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75431
Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40802
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982848
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26574
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054176
Pulmonary Alveolar Hemorrhage	DisGeNET Gene-Disease Associations	1.0	null
mellitus	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
encoded	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24012
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00491
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2686
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20614
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88631
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRCA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Perturb_11136_KO_Scap_SRP082562	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.5728
CHD7	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180937
GSE243491_1_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1296	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33049
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.935302
Plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.194
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232604
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epididymal white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5379
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91943
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849287
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21511
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145756
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282098
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.70526
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC5013636-ncomms12601-s5.xlsx-LEF1-Groups_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07925
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.00734
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53396
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16388
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977949
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01234
Pars distalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-OXT_ext_D20-OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0725
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978781
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20119
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34738
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62972
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55466
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
Perturb_17673_OE_PGRA_SRP252069	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.1671
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32443
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23275
mediated	GeneRIF Biological Term Annotations	1.0	null
PMC11236317-aging-16-205930-s001.pdf-1-CREB3_CREB3	Rummagene Transcription Factor Associations 2026	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831752
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05718
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906889
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17341
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906889
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26
meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292793
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.74366
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05105
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835803
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995163
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30846
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88631
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARA deltaORF6_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46056
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13292
crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194809
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041532
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4278
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897873
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87304
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06668
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	2.59967
required	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9844
polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87952
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32762
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3023
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.473361
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5447
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.63127
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925913
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased body fat mass	MGI Mouse Phenotype Associations 2023	1.0	null
Proliferative Diabetic Retinopathy	DisGeNET Gene-Disease Associations	1.0	null
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.025463
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850085
SYNCRIP_KD_GDS3578_86_human_MM1S	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macronutrients	GeneRIF Biological Term Annotations	1.0	null
Perturb_10714_KO_Foxo1_SRP375712	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.83074
gdm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Fatty Liver	CTD Gene-Disease Associations	1.0	1.17464
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42594
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00804
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231323
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33615
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06332
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1284_KD_TRIM26_ERP131496	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938504
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1349
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.33106
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE248858_6_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05368
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27602
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05679
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0244
regulation of Notch signaling pathway	GO Biological Process Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.905
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11666
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907635
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.064062
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872236
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - Bone Marrow - L2 - Conventional Dendritic Cell 2	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2417
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20933
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.53825
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39964
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10741
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_1111_KD_Creb3l1_SRP255011	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06133
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8195-01A-31R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858106
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071417
abnormal Purkinje cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931508
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03073
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42777
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14520_KO_Gata6_SRP023469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.48683
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Adrenocortical carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
Pregnancy Associated Hypertension	DisGeNET Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21173
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244269
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830914
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08239
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053141
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38649
Coronary Aneurysm	DisGeNET Gene-Disease Associations	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580417
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE166004_5_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14688
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01988
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09716
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9391581-mmc5.xlsx-WT_KLF4_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.724502
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41282
NUP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23476
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71293
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.67658
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.076
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79419
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35633
GSE149075_8_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC39	DepMap CRISPR Gene Dependency	1.0	6.10801
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4953
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293281
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090044
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.871121
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.413
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.636785
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586992
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90096
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
higher	GeneRIF Biological Term Annotations	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15135_KO_Foxa2_SRP102936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.26547
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833793
RUNX3	ENCODE Transcription Factor Targets	1.0	null
umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
Perturb_14688_KO_Pax6_ERP022747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.90973
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994938
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3754
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16276
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01363
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2724
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041978
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03502
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TZ-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
contractile fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.162117
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	1.45435
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900529
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47036
metabolic	GeneRIF Biological Term Annotations	1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899909
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831752
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0233
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891795
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01056
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10709_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.5478
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92679
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06464
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91098
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226484
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12672
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02907
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.44309
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.337
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306159
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19297
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13415
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78638
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.33702
CAMKK2 pathway	WikiPathways Pathways 2024	1.0	null
GF-90-DG49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319019
artery	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.84422
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
effects	GeneRIF Biological Term Annotations	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07925
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830791
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50992
ELF1	ENCODE Transcription Factor Targets	1.0	null
sirtuin1	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11274
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.39832
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9425
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4243
Acute Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
NB69	DepMap CRISPR Gene Dependency	1.0	2.84388
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	3.65328
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4424
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934531
Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46693
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Angina	DisGeNET Gene-Disease Associations	1.0	null
MEC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3256
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924479
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18998
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	2.31532
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95651
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14685
STK33_NOMO	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360036
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13726
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06388
where	GeneRIF Biological Term Annotations	1.0	null
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15216
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043783
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.52296
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69775
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.52941
nor10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
DB-56-XL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286537
FRMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37716
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75152
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25648
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
woman	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11068_KO_Dnajb9_SRP097622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6433
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635167
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.17827
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925591
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_1_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07218
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-67-DI84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641566
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16171
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81386
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968873
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372838
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18865
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00642
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055062
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Salivary_Gland-adventitial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.28232
Perturb_1275_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60397
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.838089
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7127
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03254
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07336
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32491
promoting	GeneRIF Biological Term Annotations	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245996
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949661
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H295 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040596
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50586
Human - Bone Marrow - L1 - Dendritic Cell	HuBMAP Azimuth Cell Type Annotations	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970722
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16569
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976142
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13577_OE_Msx1_SRP261181	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941778
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39749
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883782
GSE151090_5_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.31
Perirenal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0844
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Perturb_10891_OE_Trim24_SRP355273	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942502
hsa-miR-137	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132303
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.743
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388954
Prostate-luminal cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	6.22542
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407498
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468381
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Non-St-Segment Elevation Myocardial Infarction (Nstemi)	DisGeNET Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42355
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058317
Cry-Per complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479496
EFO27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40023
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21015
RBM17_02_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.848
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884406
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858106
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667408
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50939
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0108
NELFE	ENCODE Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041873
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.79325
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968642
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997092
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placental	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05192
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_3_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.860617
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831752
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.47314
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68737
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82285
Perturb_1218_KO_Zbtb7a/Zfp580_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8432
NB10	DepMap CRISPR Gene Dependency	1.0	5.46217
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27437
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
women	GeneRIF Biological Term Annotations	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06467
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4363
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7326
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.15
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490394
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12947
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373493
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARA deltaORF6_36Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76881
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02444
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84162
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00049
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28803
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.2447
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870603
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66321
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958157
TAF1	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56716
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099568
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
csx	GeneRIF Biological Term Annotations	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.5143
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316519
Hodgkin Disease	DisGeNET Gene-Disease Associations	1.0	null
Perturb_9767_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.45827
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26488
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39135
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68742
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435539
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992046
CHP134	DepMap CRISPR Gene Dependency	1.0	2.31112
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46672
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14946
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
HNRNPUL1_02_109	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.44846
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16841
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64174
Perturb_12547_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.53277
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75785
Cardiac Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.66384
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18174
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.983435
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1	ChEA Transcription Factor Targets	1.0	null
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	1.04072
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Th-1 cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938831
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15941
inhibition	GeneRIF Biological Term Annotations	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4757
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.33135
serum	GeneRIF Biological Term Annotations	1.0	null
Perturb_16639_KO_Tardbp_SRP278199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.84156
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.455978
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01026
lower	GeneRIF Biological Term Annotations	1.0	null
positive regulation of Notch signaling pathway	GO Biological Process Annotations 2025	1.0	null
Astrocyte_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043004
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_251_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7277
Polycystic Ovary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04909
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
enos	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased circulating triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868751
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96078
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13605
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.890689
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased fasting circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11143964-jciinsight-9-161356-s009.pdf-1-ZHX1_ZHX1	Rummagene Transcription Factor Associations 2026	1.0	null
probucol_mus musculus_gpl9526_gds3619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04368
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889233
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944768
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64491
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906889
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16476
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44304
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1177
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03708
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reliable	GeneRIF Biological Term Annotations	1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Chest Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876525
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890584
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Non-St Elevated Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12035
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17059
Perturb_10710_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31469
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60573
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976261
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.07132
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51848
respectively	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970708
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02592
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833968
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1928
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
indicator	GeneRIF Biological Term Annotations	1.0	null
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80947
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14412
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17713
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313706
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
upregulation	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04058
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INS-1E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11301
Necrosis	CTD Gene-Disease Associations	1.0	1.61084
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
mice	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0137
Perturb_1088_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.30832
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
Adrenal cortex cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Sepsis_Splenocyte_GSE4479	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.55749
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00687
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.183248
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51435
kinase	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2085
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925913
PMC9360325-DataSheet_3.xlsx-DEGs_DLPSvsMLPS_54DOWN-Data_file_S3D_Downregulated_DEGs_in_DCATH-2_trained_LPS-stimulated_dTHP-1_cells_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69048
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77405
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14781
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852401
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.891
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00222
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34414
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302432
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21642
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942988
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055526
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.30083
intermediate-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
hsa-miR-1291	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Perturb_10830_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.65879
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846911
fasting	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824023
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44455
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-20-WA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250037
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43836
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28689
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875908
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978781
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
presence	GeneRIF Biological Term Annotations	1.0	null
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926312
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.904744
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
White adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.863
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
lipogenesis	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052743
GSE163884_1_v_0_sumo2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31026
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.71318
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87645
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.76527
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25742
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.850923
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alcoholic liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865238
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04935
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0055
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striated muscle thin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.478843
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
type	GeneRIF Biological Term Annotations	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282483
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091468
those	GeneRIF Biological Term Annotations	1.0	null
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04026
18285497-tableS1	GeneSigDB Published Gene Signatures	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75034
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
low	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26213
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01139
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1929
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209605
provide	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857959
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21871
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250669
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100445
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
thus	GeneRIF Biological Term Annotations	1.0	null
GSE70499_0_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	2.10795
Perturb_1264_KO_Mll4_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46932
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF289	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58585
weight	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950753
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987357
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231638
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03297
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942217
HUH1	DepMap CRISPR Gene Dependency	1.0	2.21247
Acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66321
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309008
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37039
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38676
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13347
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	2.64658
marker	GeneRIF Biological Term Annotations	1.0	null
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02115
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
TCF3	ENCODE Transcription Factor Targets	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6829-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rasmc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33707
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924022
Aortic intima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905092
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479383
Perturb_1259_KO_Bap1_SRP253039	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32894
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16281
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02104
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06599
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84754
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835345
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
Perturb_10910_KO_Thbs1_SRP276889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.51026
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
DMS53	DepMap CRISPR Gene Dependency	1.0	2.0193
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885888
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13808
ELK1	ENCODE Transcription Factor Targets	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_SOX6_TrsFib_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302742
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835978
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21759
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029152
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02568
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58812
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40426
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_4966_KO_Setdb1_SRP226379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.5412
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837079
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34337
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87917
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.33702
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926119
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986985
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07425
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sirt1	GeneRIF Biological Term Annotations	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Salivary_Gland-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	2.80184
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.296537
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373012
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264353
renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86026
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045535
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160373_5_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36088
BA-19-VU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290611
PMC8454054-13059_2021_2489_MOESM17_ESM.txt--SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.33702
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43561
GSE149075_1_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSC-39	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17501
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95144
suppresses	GeneRIF Biological Term Annotations	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900552
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23838
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.52055
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15054
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.21236
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.53227
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72487
name	GeneRIF Biological Term Annotations	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-70-CUX2_CUX2	Rummagene Transcription Factor Associations 2026	1.0	null
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5452
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.250663
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886041
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
release	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50626
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4796
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82647
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938629
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868451
decreased muscle cell glucose uptake	MGI Mouse Phenotype Associations 2023	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08161
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09245
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Non-Alcoholic Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44429
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825315
cord	GeneRIF Biological Term Annotations	1.0	null
increased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919586
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69154
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.838089
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846129
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
SAT	DepMap CRISPR Gene Dependency	1.0	4.4602
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053993
Capillary pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05722
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87306
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941051
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17211
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27555
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90636
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28701
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57681
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938638
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07288
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11477
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68885
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21551
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256007
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67842
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
examined	GeneRIF Biological Term Annotations	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908366
brain	HPA Tissue Gene Expression Profiles	1.0	2.24761
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400978
saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421148
obesity	GeneRIF Biological Term Annotations	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_26_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049774
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
characterized	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971774
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958391
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.452
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05553
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11074_KO_Prkcb_SRP330448	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.2073
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336073
Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00986
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929584
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4680-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TEAD4-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of signal transduction	GO Biological Process Annotations 2025	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.378
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940521
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_10872_KO_fatp2_SRP229353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.91343
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947349
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953374
Medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
limiting	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63404
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29801
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12238
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856254
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897418
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903367
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80601
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09808
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12931
CE-20-VA70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200581
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15737
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
over	GeneRIF Biological Term Annotations	1.0	null
LB2241-RCC	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21093
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38959
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.94909
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879298
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905559
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72431
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941701
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10937_KO_Endov_SRP247228	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.66194
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22297
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF268	DepMap CRISPR Gene Dependency	1.0	2.91227
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946992
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01003
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454799
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	2.08427
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63473
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03144
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966353
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054571
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77244
Cachexia	DisGeNET Gene-Phenotype Associations	1.0	null
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57631
PMC12903452-mmc5.xlsx-ST2-2_OCT4_Off_Targets-Target_Gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32568
low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.151
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08721
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149075_8_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.331352
liver	HPA Tissue Gene Expression Profiles	1.0	0.987594
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881396
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepatic steatosis	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941287
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8672_KD_Smyd4_SRP142426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952827
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836392
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091245
SCC-9	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05885
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Human_RORC_DC_signature_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01821
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
useful	GeneRIF Biological Term Annotations	1.0	null
CHP212	DepMap CRISPR Gene Dependency	1.0	2.34182
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Liver Cirrhosis, Alcoholic	DisGeNET Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056244
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal lipid metabolism	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95352
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65629
SNU201	DepMap CRISPR Gene Dependency	1.0	2.12693
SKNDZ	CCLE Cell Line Gene Expression Profiles	1.0	1.87285
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atherogenic Dyslipidaemia	DisGeNET Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59038
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956305
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867539
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868513
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299514
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.63182
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926615
triglyceride-rich plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.565
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37807
EZH2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74583
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17836
Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9391581-mmc4.xlsx-WT_KLF4_vs_GFP-activated-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1762
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07985
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928122
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MHHCALL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60083
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.714
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adipogenesis	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.770016
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
positively	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50791
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308967
Organum vasculosum laminae terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906512
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862197
Perturb_11325_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.69923
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10014
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07081
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16826
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37835
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18015
Perturb_14687_KO_Pax6_ERP022747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03292
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38883
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
inhibiting	GeneRIF Biological Term Annotations	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41349
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842675
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10053
liver	GeneRIF Biological Term Annotations	1.0	null
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9415
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868751
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855111
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11238
Prostate adenocarcinoma_PRAD_TCGA-EJ-5503-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8954
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04701
Non-St Elevation (Nstemi) Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
myofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.478843
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCC142	DepMap CRISPR Gene Dependency	1.0	2.44842
PMC12592558-41419_2025_8097_MOESM4_ESM.xlsx-downregulated_3_-_DATASET_1-RNA_Seq_analysis_upon_lncMB3_KD_in_D283_Med_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11528
content	GeneRIF Biological Term Annotations	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3201
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14878
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48316
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32817
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46973
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
adolescents	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872069
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841023
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.550608
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839823
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.804
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29993
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05704
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942217
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899627
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89088
POLR2A	ENCODE Transcription Factor Targets	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04909
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Alcoholic hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.656
hsa-miR-4776-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23226
syndrome	GeneRIF Biological Term Annotations	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387116
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907883
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61675
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.461261
hsa-miR-3937	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49626
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197209
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4751	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945498
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58054
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10633
capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657054
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39793
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ES8	DepMap CRISPR Gene Dependency	1.0	2.3817
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393848
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4933
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
signal	GeneRIF Biological Term Annotations	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1648	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47719
Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36309
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00649
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77767
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.48153
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35782
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9c2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7012_Mut_Htt_SRP043967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74609
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978781
myocardial	GeneRIF Biological Term Annotations	1.0	null
GSE70499_4_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Paroxysmal Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10205
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942217
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04778
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56423
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229247
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168381
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04723
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_233_KD_BRG1_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	2.11287
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38628
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965816
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.60111
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44896
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41804
Perturb_12058_KO_Stat5a/Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8496
Perturb_16356_KO_RBPj_SRP162308	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.17063
although	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47298
H3K36me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.36851
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05185
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930868
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922211
POU5F1-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.828616
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08542
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918825
SCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45447
decreased locomotor activity	IMPC Knockout Mouse Phenotypes	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055162
fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699444
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2157
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.071087
15374961-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874363
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13757
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - PBMC - L2 - Conventional Dendritic Cell 2	HuBMAP Azimuth Cell Type Annotations	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	2.04276
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22892
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE149010_0_v_4_dars2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38883
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900331
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85499
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34707
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875736
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064195
SP2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11921
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
vegfr2pi3kakt	GeneRIF Biological Term Annotations	1.0	null
EM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6141
Capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367972
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914304
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844103
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416771
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07372
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
Myofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837728
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05611
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-20-WA90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237707
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Fibrosis	CTD Gene-Disease Associations	1.0	1.23806
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12711
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880999
breast epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
Preadipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.739
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01331
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954468
SUM149PT	DepMap CRISPR Gene Dependency	1.0	3.67914
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74296
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33185
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73428
reducing	GeneRIF Biological Term Annotations	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
fatty liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.247501
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875986
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00765
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.6748
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05155
assessment	GeneRIF Biological Term Annotations	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12914
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065142
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04814
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89099
Perturb_11103_KO_Depdc5_SRP219943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06333
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987441
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01944
k562	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69774
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851889
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050142
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871421
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.25
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.67851
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.988165
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.29722
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	1.81753
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830914
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05816
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02839
GSE200352_9_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08271
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
fed	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.854765
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02025
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42615
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12512047-Table2.pdf-30-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201326
pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13383
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.368
LU-65	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1813
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15752
UBTF	ENCODE Transcription Factor Targets	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
YY1_01_18	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.24777
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970708
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493816
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471836
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99349
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20445
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2041
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906225
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39629
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891141
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.924
SF172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65324
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01803
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.552888
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850085
Edema	CTD Gene-Disease Associations	1.0	1.33494
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839823
Sarcoma_SARC_TCGA-DX-A1L0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029124
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18705
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986295
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9929
TD-40-ZR64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348114
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998561
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201599
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869595
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_15543_KD_Map3k7/Chd1_SRP201304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.31844
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02425
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83192
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
HCC2935	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47333
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906889
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.850923
WSUNHL	DepMap CRISPR Gene Dependency	1.0	4.69377
Nonalcoholic Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925913
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99086
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00895
Perturb_128_KD_Cebpb_SRP041765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2838
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30045
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989942
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	3.40798
gestational	GeneRIF Biological Term Annotations	1.0	null
acute	GeneRIF Biological Term Annotations	1.0	null
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597374
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828725
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10532
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11299_KO_Bmal1_SRP153814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35748
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254737
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41665
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859183
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6374
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06796
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.96753
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.30252
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KP363T	DepMap CRISPR Gene Dependency	1.0	2.18561
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_5day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.13028
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848932
Perturb_10858_KO_Sirt6_SRP190930	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54242
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01146
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874819
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.06653
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.09628
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.936584
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36485
obese	GeneRIF Biological Term Annotations	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
PMC10940914-mmc4.docx-0-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46877
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.21344
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364267
increasing	GeneRIF Biological Term Annotations	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244685
Idiopathic scoliosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
REST	ChEA Transcription Factor Targets	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882347
hsa-miR-4267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94074
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13571
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16724
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38217
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052164
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
age	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_upregulated-Genes_upregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.74547
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.412
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07925
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838819
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46154
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850085
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878107
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0255
Perturb_4367_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.62383
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071389
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	2.1955
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.13943
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50079
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37687
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17353
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
transcriptional	GeneRIF Biological Term Annotations	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04645
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475423
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN319	CCLE Cell Line Gene Expression Profiles	1.0	2.00291
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fat	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59493
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09515
59M	DepMap CRISPR Gene Dependency	1.0	3.27303
Perturb_10941_KO_Fto_SRP094101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.5229
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60904
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267903
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.850923
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042535
HCV JFH1_168Hour-Huh7_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.35387
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_WT_KLF4-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04255
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67711
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988162
dietary	GeneRIF Biological Term Annotations	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39511
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
p0001	GeneRIF Biological Term Annotations	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16386_Mut_Rps2_SRP277547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.42106
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679105
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.82762
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75078
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.926598
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.457987
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82065
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF15_02_106	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.27302
impaired	GeneRIF Biological Term Annotations	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849194
troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.481661
Lymph_Node-cd141-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0437347
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67352
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-12_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214313
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040714
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plasma	GeneRIF Biological Term Annotations	1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55715
PAX5	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25341
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.34635
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972311
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1237
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.78129
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05093
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21384
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07717
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2157
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.850923
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55478
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1263_KO_Mll3_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.90173
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658678
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Spinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22261
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43581
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223419
Perturb_11122_KD_Eif3m_SRP162708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.39486
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983239
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35078
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Perturb_6495_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE70499_0_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.84371
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4214
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15292
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8156-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12502
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326395
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854443
SE-81-RI20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213043
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08467
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2469
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42777
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19509
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853017
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25373
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2622
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11868_OE_Ezh2_SRP059688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.93591
Large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96197
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23289
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
insulin resistance	MGI Mouse Phenotype Associations 2023	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11166884-mmc4.xlsx-Table_S3-Table_S3_proinflammatory-EC2_comparison_between_WT_and_TG_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.329935
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
EGR1	ENCODE Transcription Factor Targets	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05539
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07864
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.366
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60817
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59388
icSARA deltaORF6_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.09549
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33749
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07749
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60646
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02115
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842568
AE-71-CB15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258724
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22683
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26726
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20203
Depression	DisGeNET Gene-Disease Associations	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18248
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sex	GeneRIF Biological Term Annotations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49174
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977823
hsa-miR-4732-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_16962_KD_PAX2_SRP044867	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
pathways	GeneRIF Biological Term Annotations	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60466
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05092
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.34896
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01193
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.24041
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56422
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.969167
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE149075_6_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mechanisms	GeneRIF Biological Term Annotations	1.0	null
GSE158815_1_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053501
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17957
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370668
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82965
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0953
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PECAPJ34CLONEC12	DepMap CRISPR Gene Dependency	1.0	2.92497
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345943
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26116
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29341
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
cardiac	GeneRIF Biological Term Annotations	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11089_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.29176
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980044
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47575
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05139
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88631
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.885301
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
impaired coordination	MGI Mouse Phenotype Associations 2023	1.0	null
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985715
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982083
Hypercholesterolemia	DisGeNET Gene-Disease Associations	1.0	null
HCC1500	CCLE Cell Line Gene Expression Profiles	1.0	1.69074
Hypertrophy	CTD Gene-Disease Associations	1.0	1.67376
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09417
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.1334
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
Perturb_15064_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.77437
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04978
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5734
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469794
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4907
an3ca	HPA Cell Line Gene Expression Profiles	1.0	1.07811
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - PBMC - L3 - Conventional Dendritic Cell 2_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94541
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13888
CREB1	ENCODE Transcription Factor Targets	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.662672
TGFBR2_knockout_293_GSE46211	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75791
Striated muscle thin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.427
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
regulation of Notch signaling pathway	GO Biological Process Annotations 2023	1.0	null
tolerance	GeneRIF Biological Term Annotations	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.734824
UF-85-NE30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50118
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82008
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03697
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07184
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.80762
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05646
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90986
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TP-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
L363	DepMap CRISPR Gene Dependency	1.0	4.36338
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07295
acetylation	GeneRIF Biological Term Annotations	1.0	null
Stable Angina	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE160373_8_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940148
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	2.60856
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.344
Perturb_10727_KO_Mettl14_SRP282531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.70502
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15541_KD_Map3k7_SRP201304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.54167
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60932
GSE149075_3_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
icSARA deltaORF6_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44075
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5624885-41537_2017_33_MOESM1_ESM.xlsx-SIT1-SIT1_Top_500_differentially_expressed_genes_with_perturbations_in_CNTNAP2_carrier_NGN2-neurons_using_DESeq2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829037
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.850923
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96117
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE107854_2_v_0_prmt5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95222
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9458
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11782
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914159
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.003717
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23319
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65111
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
GTEx Stomach 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.0264
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00321
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83466
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094067
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11318_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.92138
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ID-90-NM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285713
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
D283MED	DepMap CRISPR Gene Dependency	1.0	3.91611
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345628
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29338
GSE200352_10_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926893
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62784
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.111
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875908
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979334
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958361
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.04902
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20239
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.745938
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
therapy	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951686
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01146
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
condition	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916942
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941293
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893291
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900559
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46367
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22848
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899909
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18378
Cerebrovascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21476
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cell body fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
FOS	ENCODE Transcription Factor Targets	1.0	null
LU65	CCLE Cell Line Gene CNV Profiles	1.0	1.7902
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29592
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403772
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.94142
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911275
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38962
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
PMC8481886-Table_1.xlsx-A_subsets-fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6339
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181589_1_v_0_spred1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65829
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08664
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94161
protective	GeneRIF Biological Term Annotations	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	2.2808
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969244
aging	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.55
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07698
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949238
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22671
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080502
DB-40-HA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409234
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34134
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51335
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00647
MAX	ENCODE Transcription Factor Targets	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.850923
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02115
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885209
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36039
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intermediate coronary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71736
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936289
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292616
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16627
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056423
Left middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
selection	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935217
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.11023
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842401
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07184
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0639
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20175
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11797
EE-32-EY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217522
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19509
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03063
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02036
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5514
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.090718
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01973
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04267
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
coactivator	GeneRIF Biological Term Annotations	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05669
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.439
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11604901-13555_2024_1298_MOESM1_ESM.pdf-23-SP2_SP2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_3466_KO_Chd4_SRP076455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.028867
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orf	GeneRIF Biological Term Annotations	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06999
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.36757
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884751
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311984
YY1_KD_GDS3788_488_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469211
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.074
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
control	GeneRIF Biological Term Annotations	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839823
Perturb_11148_KD_Cx43_ERP124601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.80588
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	1.0	1.40031
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14587_KO_ROBO3_ERP135745	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.65607
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.56336
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_3-SUPPLEMENTARY_DATASET_3_AML3_AzaC_WIMSi_246_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Perturb_11223_KO_Mkrn1_SRP149173	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.3106
GSE160373_1_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04797
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10732_KO_Depdc5_SRP311760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.12352
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13724
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430148
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58259
Perturb_15752_KO_Ezh2_SRP096837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
group	GeneRIF Biological Term Annotations	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893362
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06885
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17031
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	3.63284
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26906
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
infarction	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiomyoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051528
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11374
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.419
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1671
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.852085
rectum	HPA Tissue Protein Expression Profiles	1.0	0.850923
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.48281
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07376
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96059
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14384
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91304
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932062
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2247
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09121
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.60649
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2942-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867181
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0973
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967894
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20179
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20528
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044141
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39318
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.509192
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91255
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59599
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978781
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946992
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16147
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4659b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16514
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08336
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44128
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H11A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28199
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84754
dysfunction	GeneRIF Biological Term Annotations	1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19858
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05861
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959689
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50372
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61725
mean	GeneRIF Biological Term Annotations	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2536
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111501,GSE111502_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59387
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hyperplasia	CTD Gene-Disease Associations	1.0	1.02783
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
secreted	GeneRIF Biological Term Annotations	1.0	null
DNA ligase III-XRCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42721
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4659a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18235
Coronary Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
diabetes	GeneRIF Biological Term Annotations	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9692
factors	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26835
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19847
p001	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07002
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3576
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23801
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64864
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01366
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959456
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50245
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12146336-Data_Sheet_1.pdf-13-RHOXF1_RHOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
involve	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33398
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
93T449	DepMap CRISPR Gene Dependency	1.0	2.68885
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diagnosing	GeneRIF Biological Term Annotations	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17611
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15181
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06089
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1287
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01601
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05624
CHD2	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88631
TE617T	CCLE Cell Line Gene Expression Profiles	1.0	1.49717
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
exhibit	GeneRIF Biological Term Annotations	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_0_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
maternal	GeneRIF Biological Term Annotations	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.595686
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08095
D502MG	DepMap CRISPR Gene Dependency	1.0	3.91041
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10778_KO_Xbp1_SRP051964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.22655
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514989
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1271_KO_Adar_SRP132963	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.4752
EF-80-OD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276437
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39449
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.55252
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16419
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994938
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917727
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0569
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.1
STK33	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73984
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Sleep Apnea	DisGeNET Gene-Disease Associations	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20168
Perturb_2089_OE_hTR_SRP179030	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35633
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxidation	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41051
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08815
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99233
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.951
Perturb_17732_KO_Tmprss2_SRP046010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00678
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.28
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Macrophage foam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.201
Endothelial Dysfunction	DisGeNET Gene-Phenotype Associations	1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
preventing	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BE-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.418
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828807
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51848
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16891
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_1-SUPPLEMENTARY_DATASET_1_AML3_AzaC_SigDiff_1147_Note_to_reviewers_-_view_these_files_as_xls_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.81
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208481
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01803
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33398
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249794
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42615
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01237
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23275
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01582
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859247
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13446
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86829
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982898
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27091
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964754
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23824
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3887
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.981428
Liver Diseases	CTD Gene-Disease Associations	1.0	1.29843
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83137
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6335_KO_MLL4SET_SRP221512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.9736
FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pediatric Obesity	DisGeNET Gene-Disease Associations	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845051
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512887
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24658
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948997
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05475
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203158_5_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149075_1_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96449
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RSV-A2_24Hour-B6.129PF1_J_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.49411
insulin	GeneRIF Biological Term Annotations	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.849
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15291
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.145
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71519
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69668
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333368
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797915
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964276
Weight Loss	CTD Gene-Disease Associations	1.0	1.01474
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0117
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222219
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.23106
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07925
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02068
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endothelial	GeneRIF Biological Term Annotations	1.0	null
fuel	GeneRIF Biological Term Annotations	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899565
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary Artery Ectasia	DisGeNET Gene-Disease Associations	1.0	null
increased liver triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
NB6	DepMap CRISPR Gene Dependency	1.0	3.99008
Perturb_12081_KO_Stat5_SRP060232	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64115
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15277_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.09999
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37658
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0016
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBE2L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05083
positive regulation of signal transduction	GO Biological Process Annotations 2023	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.126294
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22008
Perturb_14003_OE_Kcna2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.5768
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.55804
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sublingual gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	174.005
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.850923
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00189
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04701
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20516
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33749
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11260_KO_Hur_SRP396792	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59046
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
glucose	GeneRIF Biological Term Annotations	1.0	null
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843675
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4519
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03608
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38334
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55518
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47041
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968451
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16187
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
likely	GeneRIF Biological Term Annotations	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.154
deacetylase	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08233
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24085
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.14
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3533
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04267
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989215
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.757845
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33505
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32069
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981097
Perturb_11284_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.59195
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81615
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31113
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72168
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
concentrations	GeneRIF Biological Term Annotations	1.0	null
fetal	GeneRIF Biological Term Annotations	1.0	null
Prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05721
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840886
renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235167
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GSE126402_5_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3206
Neonatal Abstinence Syndrome	CTD Gene-Disease Associations	1.0	1.06297
JUND	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2870-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49565
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232614
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60359
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041942
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16334
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.458
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306785
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857576
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_mus musculus_gpl5137_gse10900	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364513
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830821
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOS3	CCLE Cell Line Gene Expression Profiles	1.0	1.42368
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963737
dyslipidemia	GeneRIF Biological Term Annotations	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883401
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884454
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216158
Acute Coronary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10041
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14977
Perturb_18151_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.58793
abnormal locomotor activation	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_11242_KO_Sirt6_SRP190930	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.4674
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12559
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47561
BICR78	DepMap CRISPR Gene Dependency	1.0	3.19169
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.86781
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907795
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11304
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Differentially_expressed_genes_of_RORC_cluster_RORgt_DC_compared_to_other_clusters_in_each_dataset_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63902
skeletal	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98717
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02228
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08584
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826443
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE149075_8_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5792-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11197_KD_Pten_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.342
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13486
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944982
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.91336
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61356
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_10936_KO_Oxr1a_SRP102450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.70612
Perturb_11251_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.585
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27112
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23765
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70919
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12629
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	2.11939
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15164
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01326
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11173_Mut_Ctbp2_SRP188140	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.48838
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58493
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70612
laminin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
Perturb_6331_KO_Gaa_SRP042287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18437
coronary	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A4EM-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41478
GSE70499_4_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346605
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15221
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797435
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10271
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207548
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.965252
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19676
Perturb_10596_KO_Nr1h3/Nr1h2_SRP351084	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.11549
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31377
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02486
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261228
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18227
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.57409
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0427
AD-72-RI24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229599
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01803
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14398
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29208
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8418_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19056
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24945
HCC70	DepMap CRISPR Gene Dependency	1.0	2.16172
Cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28151
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858106
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4371
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13012
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	2.00807
Perturb_10909_KD_Eif3m_SRP157047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.39486
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40802
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.8668
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16147
impaired glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.47514
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970631
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957625
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06445
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC9	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2157
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00411
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3419
paneth cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356558
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14552_KO_Abcc8_ERP018163	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
blood	GeneRIF Biological Term Annotations	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vascular endothelial cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06916
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206379
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42577
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21076
Perturb_14865_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.68821
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064595
D283MED	CCLE Cell Line Gene Expression Profiles	1.0	1.58839
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4713-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Osteoarthritis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14004_OE_Kcnj2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.9834
parameters	GeneRIF Biological Term Annotations	1.0	null
PMC11428309-12920_2024_2011_MOESM1_ESM.pdf-2-TSC22D1_TSC22D1	Rummagene Transcription Factor Associations 2026	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.05972
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58877
hsa-miR-3135	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tongue-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	0.104472
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169571_3_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3	Rummagene Transcription Factor Associations 2026	1.0	null
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250073
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79726
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
positive regulation of Notch signaling pathway	GO Biological Process Annotations 2023	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.07553
Human - Bone Marrow - L2 - Precursor Myeloid Dendritic Dell	HuBMAP Azimuth Cell Type Annotations	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.784
Perturb_7002_KO_Acadl/Acadvl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3405
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.825
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.023
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.49603
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01048
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071389
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A1NK-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abundant	GeneRIF Biological Term Annotations	1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04267
parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0201
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.422
ZNF143	ENCODE Transcription Factor Targets	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.850923
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910254
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.197662
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02918
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052689
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69696
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26709
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0431
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6632
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322519
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99753
diseases	GeneRIF Biological Term Annotations	1.0	null
non-alcoholic fatty liver	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04832
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864737
Behcet Syndrome	DisGeNET Gene-Disease Associations	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11252_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.0998
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306443
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069803
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00024
Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.42645
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.901886
Venous blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.597
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
regulated	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06981
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13524_KD_Brd9_SRP333303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0307
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35552
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851403
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853893
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357483
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59316
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10770_KO_Jnk1/Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51478
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04851
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34629
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10515
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prader-Willi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42728
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62318
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858106
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99018
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88154
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638404
CFPAC1	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45309
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pgc1alpha	GeneRIF Biological Term Annotations	1.0	null
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.10621
bone disease	GWASdb SNP-Disease Associations	1.0	0.160785
Obstructive sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29164
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09388
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
independent	GeneRIF Biological Term Annotations	1.0	null
3T3-L1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.21974
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108899
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.69612
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06674
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.09566
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02214
RCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34395
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858449
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867357
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270561
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08549
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
men	GeneRIF Biological Term Annotations	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
actions	GeneRIF Biological Term Annotations	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25691
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scoliosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_10860_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529479
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50948
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19125
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25292
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92281
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063804
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2097
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44884
PMC12146336-Data_Sheet_1.pdf-13-ENSG00000101883_RHOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18188
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08591
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DF-95-CY55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201296
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3766
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.868205
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rosiglitazone_mus musculus_gpl1261_gds3798	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12122724-41467_2025_60028_MOESM6_ESM.xls-Supplementary_Table_4_Marker_g-Supplementary_Table_4_Marker_genes_of_six_TPIT_tumor_subtypes_TBX19	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11141_KO_Hdac3/Scap_SRP082562	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72454
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25952
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13493
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20903
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38377
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - PBMC - L3 - Conventional Dendritic Cell 2_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
USF1	ENCODE Transcription Factor Targets	1.0	null
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38832
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6733
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased food intake	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31744
SNU1214	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75875
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51527
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99195
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976288
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952146
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67644
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08692
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246913
MYOG	ENCODE Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
muscle	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81767
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SSB_02_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.45943
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11457
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25406
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45775
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13145
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235839
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Y-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884868
PCBP1_02_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.979
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909488
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57755
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945498
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Z-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05623
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1167
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44344
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13603
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271592
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.37
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.2862
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08253
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00234
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.99022
males	GeneRIF Biological Term Annotations	1.0	null
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85886
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.76613
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00924
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40426
irrespective	GeneRIF Biological Term Annotations	1.0	null
Cleft Palate	CTD Gene-Disease Associations	1.0	1.22501
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231022
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_8411_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.02546
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00624
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06147
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911619
Coronary atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58493
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3658
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10945
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35143
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.907133
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11519154-253_2024_13316_MOESM1_ESM.pdf-17-ZNF460_ZNF460	Rummagene Transcription Factor Associations 2026	1.0	null
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930919
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0546
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FUS_02_124	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.1375
peptide	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275927
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.838089
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
increased percent body fat/body weight	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45189
Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.427
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
markers	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0857
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1789
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846277
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SF172	DepMap CRISPR Gene Dependency	1.0	2.52379
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45925
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05774
synthase	GeneRIF Biological Term Annotations	1.0	null
MDAMB415	DepMap CRISPR Gene Dependency	1.0	2.54617
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5124
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.247955
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22155
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23459
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934688
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25874
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25406
Brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631123
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.24268
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916446
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166167
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135991
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975527
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65301
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.02
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51948
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07638
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865287
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089808
methylphenidate_mus musculus_gpl11180_gse33619	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047622
extracellular region	GO Cellular Component Annotations 2015	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4167
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043436
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111089
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Exanthema	CTD Gene-Disease Associations	1.0	1.06406
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.889402
fatty	GeneRIF Biological Term Annotations	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05614
AA-91-WB95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319655
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15393
Morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21782
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.19816
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46695
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12224
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69078
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078077
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
given	GeneRIF Biological Term Annotations	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.64253
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40525
PMC11426526-ppat.1012555.s011.xlsx-Shared_DEG-Shared_DEG_between_MDDC_C91-PL_and_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06833
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.1381
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24329
PMC4905481-oncotarget-07-11397-s003.xlsx-CtBP1_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AREB6	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.875536
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3941
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12506
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5469
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01728
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236251
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.66596
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901142
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15478
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07799
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27356
resistance	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04308
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447647
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867702
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.5824
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40167
LMO2	ChEA Transcription Factor Targets	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
correlated	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00906
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MV411	DepMap CRISPR Gene Dependency	1.0	2.10735
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3109
GSE149075_1_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912363
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.82248
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.2221
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51012
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1278_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.48834
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217361
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y0-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04723
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2636
Degenerative Polyarthritis	DisGeNET Gene-Disease Associations	1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.228
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13896
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20728
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1426
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04723
NH12	DepMap CRISPR Gene Dependency	1.0	4.20245
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00329
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10216
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459