association	dataset	threshold value	standardized value
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02324
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07124
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70429
A253	GDSC Cell Line Gene Expression Profiles	1.0	1.7487
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973565
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.157
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13672
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82562
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	200.577
dimeric	GeneRIF Biological Term Annotations	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.52871
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47668
Perturb_8534_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.63894
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	3.31547
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11836
BRD-K92849826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07197
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29049
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957842
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67936
PADI4	ChEA Transcription Factor Targets	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87466
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MCF7_SRT2104_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140149
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25029
PMC12099056-research.0703.f1.pdf-12-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76487707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0832
AMPK gamma-3_KO_GDS1938_163_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
K562_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197834
MCF7_XAV-939_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156382
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03165
dehydrocholic acid-1523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0373
tanespimycin-428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167815
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03969
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
MCF7_PJ34_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0249944
cervical	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900521
18786252-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46002
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	4.65531
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00517
Perturb_9414_KO_Mettl14_SRP136010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.23952
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40258
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
pre-B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
four	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79667
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18104
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPR116	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19478
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934364
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53996
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900422
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.91624
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863219
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83049
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63116
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14802
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868705
K562_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162788
RMGI	DepMap CRISPR Gene Dependency	1.0	2.80494
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11250262-41588_2024_1798_MOESM4_ESM.xlsx-ST18_665_top_menarche_genes-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21547369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07059
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K58300049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09401
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Motesanib Diphosphate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191766
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950125
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06669
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03237
KMS18	DepMap CRISPR Gene Dependency	1.0	3.65367
INTS3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20138377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64366
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9726_KD_SF3B1_SRP278642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20174
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22107
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K89524688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11813
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41501
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.60767
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10356
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.441312
GSE183271_2_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17669
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22978
BRD-K01951210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.59926
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
K562_Raltitrexed_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193437
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39582
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	2.00611
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20038
mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277549
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74184
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2104
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67878
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55998
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44799
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
bucladesine-842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943443
out	GeneRIF Biological Term Annotations	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.055
A549_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217943
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43458
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48178
attributed	GeneRIF Biological Term Annotations	1.0	null
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06717
roxithromycin-4192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151455
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Raltitrexed_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234913
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4007
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12556
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12750296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11827
PMC7288929-aging-12-103203-s002..xlsx-downregulated_by_BCL6-TargetID_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53347
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11558
RELA	ENCODE Transcription Factor Targets	1.0	null
KIJK	DepMap CRISPR Gene Dependency	1.0	2.56488
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06334
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872831
IMR-5	GDSC Cell Line Gene Expression Profiles	1.0	2.16721
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
7979_SLC22A23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533029
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86461
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70767
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93146
BRD-K78902613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10542
K562_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193259
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_283_KD_BRD9_SRP303690	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68305
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05863
MCF7_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014046
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34676
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89046
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02728
FADU	CCLE Cell Line Gene CNV Profiles	1.0	1.34874
BRD-K00557942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07346
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6983
A549_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121885
females	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896591
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33117
CRCGN008_HEPG2_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28357
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
DYRK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39996
FTC-133	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64586
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01902
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97877
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52276
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36868
Phenoxodiol	DrugBank Drug Targets	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955501
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01059
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41382
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24584
GTEX-R55E-1126-SM-48FDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8395
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29192
K562_Alendronate sodium trihydrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157161
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EA-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01083
K562_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190155
CDC7_knockdown_109_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.95988
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940732
rna	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
K562_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015877
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.06378
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08828
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18438502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76178
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02642
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5933-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00829
MEG-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
A549_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175237
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230755
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02438
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34116
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0962
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28154
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14189
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.163
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.0319
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-34b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49388
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10679653-mmc3.xlsx-ISL1_KO_Markers-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996724
BRD-K76193544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06878
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955674
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969449
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66811
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5005
HIPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68594
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DB	CCLE Cell Line Gene Expression Profiles	1.0	1.37789
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vernakalant	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39119
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190432
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC1	CCLE Cell Line Gene Expression Profiles	1.0	2.84521
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08386
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HELLS	Pathway Commons Protein-Protein Interactions	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6662
BRD-K52582315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05941
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39438
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30156
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993714
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE119973_5_v_1_phf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210322
MYC	ENCODE Transcription Factor Targets	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825372
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845817
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8985
K562_JQ1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014514
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837504
MCF7_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153514
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02619
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73813
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.75
GABPA	ENCODE Transcription Factor Targets	1.0	null
A549_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159546
MCF7_Daphnetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215562
Eplerenone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11297914-41389_2024_531_MOESM1_ESM.pdf-228-ZNF277_ZNF277	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93735
Osteoarthritis_Synovial Membrane_GSE1919	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48547
RUNX1	ChEA Transcription Factor Targets	1.0	null
SCHEMBL5061501	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.5
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213436
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00829
Ebola hemorrhagic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01406
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4225
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197099
GTEX-RTLS-0726-SM-46MV4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.0167
GTEX-OHPL-1826-SM-2YUN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00534
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06876
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8224
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934117
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839517
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22978
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898957
NSC19883	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
A549_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141925
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72999
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13223
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34206
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10367
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10175
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47371
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35998
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12805
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914609
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016311
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068584
hsa-miR-138	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01392
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907623
vh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10159
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16615
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.50356
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32121
BRD-K18117162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06478
lisuride-6682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Maraviroc_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019355
ciclacillin-4536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
electron transport chain	GO Biological Process Annotations 2025	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09217
MCF7_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178317
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2356
MCF7_BMS-911543_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158474
MCF7_PCI-34051_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168005
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33367
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10281
KAT2A	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3792
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
JUN_01_230	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58542
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
MRK-nu-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.74614
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5064
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46483
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836853
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27517
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02754
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_ENMD-2076_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174447
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7076
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_2029_KO_Chd4_SRP173193	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.371
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935693
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFC1	Pathway Commons Protein-Protein Interactions	1.0	null
K562_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0309912
K562_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191489
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879938
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74236
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65676
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxidase	Phosphosite Textmining Biological Term Annotations	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364331
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63857
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31004
BRD-K31575995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06512
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12874
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22846
metergoline-1606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
NPLOC4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05865
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26273
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08105
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14081
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3424
mef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.818576
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17713
ALPI	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pimavanserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02736
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909871
Superior colliculus, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37957
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12399
SLC2A1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copper	HMDB Metabolites of Enzymes	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22301
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12922
resulting	GeneRIF Biological Term Annotations	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07654
Perturb_14647_KD_SOX9_SRP308338	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.7261
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70973
MCF7_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150674
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829478
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2316
MCF7_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0293921
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053721
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKCD	PhosphoSitePlus Substrates of Kinases	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3952
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.759914
BRD-K04275703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13789
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854745
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179402
SARS-CoV_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46237
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235578
NR2C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
minus	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78626
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67562
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_PFI-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150282
SP1	Pathway Commons Protein-Protein Interactions	1.0	null
Cholangiocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
A549_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170435
NCIH146	CCLE Cell Line Gene Expression Profiles	-1.0	-2.47892
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27881
Carbamazepine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00166
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68385
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.44139
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146109
BRD-K10412976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18411
MCF7_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134955
STAT1	ENCODE Transcription Factor Targets	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K29458940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3521
Perturb_14655_KD_TCF7L2_SRP050497	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FOS	ENCODE Transcription Factor Targets	1.0	null
TCERG1	Pathway Commons Protein-Protein Interactions	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	2.16778
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0796
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48765
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956517
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T3M10	CCLE Cell Line Gene Expression Profiles	1.0	1.49152
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0932
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79509
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29819
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23265
MCF7_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152371
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19564
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918772
BRD-K44509164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82966
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6881
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2571
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14253
GSE202434,GSE202438_9_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
decrease	GeneRIF Biological Term Annotations	1.0	null
STK155799	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.25
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924503
PMC11732233-mmc1.pdf-419-TCF4_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0224979
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986468
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76126
TCF7L2	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7959
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
MCF7_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0103085
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96364
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rat-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91507
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936449
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAD	HMDB Metabolites of Enzymes	1.0	null
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861446
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26892
TAF7	ENCODE Transcription Factor Targets	1.0	null
MCF7_Obatoclax Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0113124
Topiramate	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67472
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865646
USF1	ENCODE Transcription Factor Targets	1.0	null
suppressed	GeneRIF Biological Term Annotations	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20422
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
necessary	GeneRIF Biological Term Annotations	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.64212
MCF7_Ramelteon_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166679
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226858
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.67071
BRD-K62007935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16989
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35136
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
K562_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211258
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05779
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LC1F	CCLE Cell Line Gene Expression Profiles	1.0	1.3703
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73505
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69303
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918345
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	0.989107
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NP118809	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136963
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901469
2907_FAM216A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621356
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1776
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15685
RPMI7951	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32703
CHEMBL200403	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.07
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1921
CHAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15658
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03753
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055953
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019846
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868706
PHA-00745360-4562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195773
hsa-miR-4678	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MCF7_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158802
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.04173
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20862
K562_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0228937
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908369
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.985486
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72708
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1085
egcg	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3006
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13211
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969459
BRD-K03351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73499
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8273
BRD-K63285694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2427
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30541
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35345
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851012
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0075
GATA2	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16004
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15233
PCLO	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175976
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09086
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2856
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2448
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875989
theophylline-2986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66033
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7198
CCNT2	ENCODE Transcription Factor Targets	1.0	null
POLG	Pathway Commons Protein-Protein Interactions	1.0	null
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45961
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07632
MCF7_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142816
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.06144
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02691
Perturb_13937_KD_PHOX2B_SRP345639	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7069
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6224
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
diphemanil metilsulfate-1912	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42027
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.616665
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07402
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861552
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-491-ZNF367_ZNF367	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A63759745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11319
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	4.40014
MCF7_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148584
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86151
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
norcyclobenzaprine-4190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20622
MCF7_GSK-LSD1 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208693
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05279
protein disulfide oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
ITGB1	Pathway Commons Protein-Protein Interactions	1.0	null
LB647-SCLC	GDSC Cell Line Gene Expression Profiles	1.0	1.76779
FOXA1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971748
hsa-miR-3064-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
K562_A-366_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150987
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.56803
Perturb_10715_KO_Ogt_SRP216750	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831735
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069036
electron transport chain	GO Biological Process Annotations 2023	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78919
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09513
u87	HPA Cell Line Gene Expression Profiles	1.0	0.861085
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94427
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44201
NUGC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.52524
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142878
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.5952
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17775
GSE179002_3_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37355
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06823
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89637567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00369
GSE146865,GSE146866_1_v_0_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994104
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
K562_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192673
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69348
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09511
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
pkcdelta	GeneRIF Biological Term Annotations	1.0	null
MCF7_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177504
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89736
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25974714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03479
GSE199541_2_v_5_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06237
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1292
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12341_KD_METTL18_SRP235648	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21919
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.788964
A549_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171094
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03097
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.4478
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UE-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02415
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.16861
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	2.20947
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65002
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918376
K562_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163676
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76995
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14084
alar plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01061
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847892
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66879
Perturb_1711_KO_Chd4_SRP193857	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53861
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carrying	GeneRIF Biological Term Annotations	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06409
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38857
MCF7_RG108_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015364
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827342
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08159
BRD-K92079609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13964
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4327	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34081
MCF7_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147227
A549_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133095
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18115
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174153
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.728547
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.644196
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8222
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899677
IL4	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arnox	GeneRIF Biological Term Annotations	1.0	null
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00006
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90867
intermediate stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55817
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155382
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.232
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29895
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40892
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991461
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
1693_CMIP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.501797
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00792
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-331-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Primary effusion lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060088
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57102
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04476
STL336112	DeepCoverMOA Drug Mechanisms of Action	1.0	0.51
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0693
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22673
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62187
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55088
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_NM-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13345
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894518
K562_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208201
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10835
HSC39	DepMap CRISPR Gene Dependency	1.0	2.20557
715_AURKB_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537994
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.38707
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43177
A549_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156613
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
hsa-miR-505	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
EFO-21	GDSC Cell Line Gene Expression Profiles	1.0	2.01038
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951876
CAMK4	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101527_3_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867357
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19546
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239099
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-199b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75845970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02176
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82302
18440302-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16791
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29904
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5569
DICER1_KO_GDS4504_583_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH1355	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58068
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01986
MCF7_Selisistat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126149
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.57444
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898348
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.1697
MYO1B	Pathway Commons Protein-Protein Interactions	1.0	null
oxidoreductase activity, acting on a sulfur group of donors	GO Molecular Function Annotations 2015	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL2671 (FANCB)	NURSA Protein Complexes	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	2.50573
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29634
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962019
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	2.343
MYO6	Pathway Commons Protein-Protein Interactions	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45375
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16599
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4378
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16560691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42366
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214533
K562_S-Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171111
BRD-K94037108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00816
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171415
7505_RPS16_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.30738
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.98083
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46408
A549_Panobinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123244
BRD-K15008902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09382
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4656
unregulated	GeneRIF Biological Term Annotations	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01072
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995869
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0263424
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968725
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959896
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164114
ICK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97559
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66684
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81966
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55995
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21553
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61263
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86139
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.396
hsa-miR-190b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	2.12358
haloperidol-4427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.49278
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20694
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21206585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31509
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98107
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148976
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45265
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
pindolol-2238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14182
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C8-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15861
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45879
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85963
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10184
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81239
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.903465
K562_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220434
MCF7_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226474
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849879
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
K562_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181785
PMC11269579-41598_2024_67843_MOESM1_ESM.pdf-76-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04317
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03389
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160365
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-movement	Phosphosite Textmining Biological Term Annotations	1.0	null
K562_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016832
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86942
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlormezanone-4636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
contributing	GeneRIF Biological Term Annotations	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12052
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0626
Perturb_13708_KD_RNF2_SRP351230	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
UACC62	BioGPS Cell Line Gene Expression Profiles	1.0	1.04917
SALL4	ChEA Transcription Factor Targets	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72025
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hek293-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.08143
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Variegate porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Sarcoma_SARC_TCGA-IE-A4EI-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
proapoptotic	GeneRIF Biological Term Annotations	1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91366
timolol-5280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00285
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83381
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1752
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2214
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GW 3965	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836527
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4684_KD_Plag1_DRP005364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71893
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40678
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975208
membrane	GeneRIF Biological Term Annotations	1.0	null
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
rofecoxib-205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.70768
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883032
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52718
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0352
IWR-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	1.0	3.19834
MCF7_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188774
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21488
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77226
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21859
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11084
BRD-K21423945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14248
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909722
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27213
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913251
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13926
KRT14	Pathway Commons Protein-Protein Interactions	1.0	null
macromolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01112
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951102
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13385
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Lapatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131749
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83255
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.78155
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309986
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17523
BRD-K27620386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08574
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72503
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33003
BRD-K70039231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09721
K562_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190785
A549_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143822
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
K562_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181638
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42481
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
BRD-K98625375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06801
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6687
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPA1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3685	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43388
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42778
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4186
Atrial heart septal defect 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Rectum adenocarcinoma_READ_TCGA-EI-6512-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31510639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6483
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44992
A549_ZM 447439_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198001
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01223
MCF7_PJ34_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111278
K562_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0246292
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.938
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Childhood Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBR	Pathway Commons Protein-Protein Interactions	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05648
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
vinblastine-7517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-3129-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
provided	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854644
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4236
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061722
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2425
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24834
A549_Resveratrol_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.014753
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7247-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73461
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07227
Binospirone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19389825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23711
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883825
RH00511	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21654
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141791
celecoxib-206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77663497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19789
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90381
MCF7_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260291
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154051
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62574
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63219
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCA1	Pathway Commons Protein-Protein Interactions	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865513
A549_Danusertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139063
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01681
GATA3	ENCODE Transcription Factor Targets	1.0	null
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-548aa	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30628727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43549
K562_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165045
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130679
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06127
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.757234
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0253
rac	GeneRIF Biological Term Annotations	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17915
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43254
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
inhibits	GeneRIF Biological Term Annotations	1.0	null
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100185
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15759
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08807
initiation	GeneRIF Biological Term Annotations	1.0	null
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.87001
BMI1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08882
central layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55817
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfamethoxazole-2335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_3_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897678
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01345
BHT101	CCLE Cell Line Gene CNV Profiles	1.0	1.79725
biological regulation	GO Biological Process Annotations 2015	1.0	null
Olanzapine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148148
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32958
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18871
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6235
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03265
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
side of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24119
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31064
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895531
rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374809
K562_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163425
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62618
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838091
NOTCH3	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135562
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95282
GSE250534_2_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	7.84631
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.30379
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830312
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.50298
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94593
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0257518
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149536
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177827
LM-1685-253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3672	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K04886976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23003
CCND1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875178
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
K562_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228782
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01611
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
Middle East respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
targeting	GeneRIF Biological Term Annotations	1.0	null
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15527
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VERO C1008 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064863
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44975
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05073
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.435679
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18533
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1818
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35575
BRD-K20119884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25092
phenoxodiol	CTD Gene-Chemical Interactions	1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K59658487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09527
Perturb_9162_KD_YBX1_SRP346212	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27446
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23416
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56199
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03708
A549_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207123
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20198
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48475
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847665
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZIC5_01_284	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59167
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33475
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28718
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26534
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.52998
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10041
hsa-miR-199a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7327
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884259
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72454
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	-1.0	-0.94903
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
Cholangiocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
SW579	CCLE Cell Line Gene CNV Profiles	1.0	1.79344
vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93726930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08186
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985453
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	2.03574
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18941
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83136
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74071
nih3t3	Phosphosite Textmining Biological Term Annotations	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.299997
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3397
MCF7_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157731
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74568352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81851
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183338
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K18084996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32239
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.796
BRD-K09137343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49727
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.51438
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1197	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inhibition	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14614
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7344
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3801
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
LoVo	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71224
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3931
BRD-K90230495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43016
MCF7_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167948
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51397
HCC78	DepMap CRISPR Gene Dependency	1.0	3.93489
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-SOX9_RIME_Limma-Gene_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24392
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21478
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964866
tnox	GeneRIF Biological Term Annotations	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10928_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508471
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937372
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10884
BRD-K85336956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05508
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9323
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-01A-21R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16422_KO_Ring1/Rnf2_SRP136552	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.88128
SLC25A4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-543	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
MCF7_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171944
A549_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166181
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920945
E2F6	ENCODE Transcription Factor Targets	1.0	null
ALB	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29066
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
K562_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176872
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38758
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67531
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11344
Perturb_7784_KD_BS692_SRP030639	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
VM-CUB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77281
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44779
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31729
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0478
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3493
K562_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0282351
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92202
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850309
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64266251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21523
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976473
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3433
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52769
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907353
NAD	CTD Gene-Chemical Interactions	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.859441
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08969
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.19988
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34801
LS411N	DepMap CRISPR Gene Dependency	1.0	3.79132
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6124
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41816
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160189
PMC12081695-41598_2025_1907_MOESM1_ESM.pdf-3-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214357
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.911407
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36388
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CCK81	CCLE Cell Line Gene Expression Profiles	1.0	1.46318
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5238
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80837
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8131
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90059
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29888
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25786
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4642
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40112
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
K562_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174575
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156164
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02222
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.802293
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06556
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20293
gs9l	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09191
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02183
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02355
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14043
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.08196
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70894
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6938365-pone.0226733.s018.txt--NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
RPE1SS48	DepMap CRISPR Gene Dependency	1.0	3.11673
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45187
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09303054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36948
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49653
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21188
GSE80182_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-1304	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
PMC9932992-mmc7.xlsx-S6E-Table_S6E_Per-gene_per-sample_AR_data_fibroblasts_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86489
BRD-K91022335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51871
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63012
MCF7_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143495
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diphemanil metilsulfate-4416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.845002
CTNNA1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06607
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08342
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886181
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89295
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8533
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12329
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.02546
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839572
K562_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136056
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45377
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88632
Side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177949
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.35898
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00398
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00575
MCF7_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154567
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08389
MCF7_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134147
GTEX-NFK9-0326-SM-3MJGV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06726
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147872
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31196
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04358
valproic acid-4438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6411
NFYB	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH841	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86284
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.03493
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.82432
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30711
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
MCF7_JNJ-26854165_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121026
Cervical adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
dorsolateral part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38278
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6683-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176264
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
exon	GeneRIF Biological Term Annotations	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1297
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061941
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.09995
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.857
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24941
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937556
BRD-K26194226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78425
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55562948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0223
K562_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161723
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53363
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPS27L	Pathway Commons Protein-Protein Interactions	1.0	null
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38441
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864763
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.22967
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90894
diphemanil metilsulfate-1994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3183
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71B-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	3.82715
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825689
A704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85751
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2852
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95402
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148039
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56953
Brush cell (Tuft cell)_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.960947
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30475
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167452
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888723
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69348
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7917-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206679
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07463
BRD-K37203945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27137
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03959
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974484
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882907
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6844-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.3663
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72419
fipexide-3176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14823
CREB1	ENCODE Transcription Factor Targets	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.931737
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04473
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LRRK2_mutant_33_GDS4401	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.17128
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869951
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6396
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0329028
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14066
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01894
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77325
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32791
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01139
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30852
hsa-miR-4661-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57293
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18232
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208318
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195312
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36111
SARS-ddORF6_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.45298
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4781
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
downregulation	GeneRIF Biological Term Annotations	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25456
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13851
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84148
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74907
FOXP1	ChEA Transcription Factor Targets	1.0	null
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41192699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01842
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0526-SM-4DXTH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65269
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC25A10	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
cell growth	GO Biological Process Annotations 2015	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993242
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66361
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL2793 (TRIM24)	NURSA Protein Complexes	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.66078
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74985
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
BRD-K44797534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67633
u251mg	HPA Cell Line Gene Expression Profiles	1.0	0.962205
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04138
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926733
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12097
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.918809
Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.010129
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-376a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2307
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927736
ceramide	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41153
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863427
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04383
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
K562_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160575
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0157
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221191
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00216
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53387776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01707
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84871
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58964
MCF7_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0290563
A549_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190053
dicycloverine-1983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04922
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U2AF2_02_170	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59027
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896658
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54031
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826035
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61981
K562_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0270798
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63817
BRD-K55316222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20337
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34206
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12931
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	2.6087
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7327
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27542
BRD-K21982562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40085
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7148
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52329
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.67622
A549_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156242
K562_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155566
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IgG B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30793
K562_G007-LK_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178733
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
hsa-miR-376b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68357
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72001
NCIH1618	CCLE Cell Line Gene Expression Profiles	1.0	1.41709
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04468
bt-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.771514
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154498
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0275
CRCGN014_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23726
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182169
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MCF7_Avagacestat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126183
K562_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151941
K562_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202077
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973744
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879515
BRD-K40646662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60289
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.855094
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17128952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26588
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13478
MCF7_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115098
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08666
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03961
MCF7_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189338
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08879
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08781
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04017
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15459
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06664
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72197
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12786
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1296	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
A549_SRT1720 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176654
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098655
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DEL	CCLE Cell Line Gene Expression Profiles	1.0	1.39235
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.04389
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4575
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40217
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970855
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
hsa-miR-605	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
IC-87114	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAG3_KO_GSE4063_389_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFMBT1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.789796
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861426
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7623
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29417
PRKCD	KEA Substrates of Kinases	1.0	null
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08066
CUX1	ENCODE Transcription Factor Targets	1.0	null
Ovary cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
K562_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170003
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
fluphenazine-4461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
electron	GeneRIF Biological Term Annotations	1.0	null
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27193
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
5587_NEDD8-MDP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.694831
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	1.46566
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51746
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058798
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279544
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466885
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K46445956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26303
single-organism process	GO Biological Process Annotations 2015	1.0	null
SHOC2	Pathway Commons Protein-Protein Interactions	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYRK1A	Kinase Library Serine Threonine Kinome Atlas	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12846
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10751
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Asbestosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
PRKAG3_KO_GDS1398_703_mouse_gastrocnemicus muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Epstein-Barr virus (strain B95-8)	Virus MINT Protein-Virus Interactions	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20087
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1758_KO_p300/Tet2_SRP250516	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.90889
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.5954
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830138
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10727
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933787
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6255
BRD-K16214172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30752
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256646
D458	DepMap CRISPR Gene Dependency	1.0	2.50459
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076714
BRD-K87141723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2713
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854205
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.71156
josamycin-1534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
correlates	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882369
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02398
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	1.804
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP2	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06442
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.67917
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.697366
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27536
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186376
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52868
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21462
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67727
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147676
MCF7_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149392
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27592
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49386
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56595
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20254
ETS1	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35642
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.817216
SIRNA_EIF4GI	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
apoptosis	GeneRIF Biological Term Annotations	1.0	null
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18786
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26534
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A39900448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5596
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909916
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15337
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248965
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85401814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23786
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13977
5910_NXF1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.595352
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.54217
hsa-miR-4708-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138899
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80905
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29114
sensitizes	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146871
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16143
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162558
MCF7_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0247334
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23658
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC108	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9795
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31725
tolmetin-3009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYB	ENCODE Transcription Factor Targets	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01814
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43018
BRD-K05657319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17849
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38733
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10541
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0223
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.80398
GTEX-OXRK-0326-SM-3NB3R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923474
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.2529
A549_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179201
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK10_knockdown_116_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.88248
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5177
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208147
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72777
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95735
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5585
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45454
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01425
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SUN2	Pathway Commons Protein-Protein Interactions	1.0	null
SOX2	Pathway Commons Protein-Protein Interactions	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32041
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45583
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14767
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172154
A549_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136788
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJC2	ChEA Transcription Factor Targets	1.0	null
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42688
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
External side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22777
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80956
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904333
MCF7_Patupilone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198631
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51525251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07513
HIPK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
EW8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60557
hsa-miR-4272	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37405
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ACADS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971007
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03948
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80368
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06453
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0644
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06867
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Droxinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188385
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23518
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03488
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212226
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1427
ZFYVE20	Pathway Commons Protein-Protein Interactions	1.0	null
KNS81	DepMap CRISPR Gene Dependency	1.0	3.0113
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	2.0418
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P03219	Virus MINT Protein-Viral Protein Interactions	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
naringenin-3278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207333
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97836
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42713
BRD-K13370005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45478
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16541
actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NAMALWA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0905
enhanced	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47805
MCF7_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141829
pirenperone-5274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_SRT1720 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016434
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04642
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47754
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	2.41014
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
estradiol-4432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08194
K562_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163259
zoxazolamine-1270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202063
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35025
Perturb_15748_KO_Thap11_SRP065965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.67895
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4562
Uterine Carcinosarcoma_UCS_TCGA-NF-A4X2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7933
K562_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015233
hnrnp	GeneRIF Biological Term Annotations	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62657
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74968
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01239
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58657
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-2.68329
Perturb_8302_KD_RBM22_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.72661
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50149
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05531
GTEX-XPT6-0326-SM-4B66V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85591
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5023
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15324
Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45568
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.60341
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	1.72839
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53081
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09659
Perturb_6334_KO_Fnip1_SRP260964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52768
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940988
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.19775
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23527
NUP98	Pathway Commons Protein-Protein Interactions	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59111
Perturb_9840_KD_AF10_SRP134072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.04899
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.7317
MCF7_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151121
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
arcaine-6629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03518
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18824
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20803
NOC2L	Pathway Commons Protein-Protein Interactions	1.0	null
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.65841
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14147
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.22336
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98363
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxygen	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055604
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020762
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hydroxyzine-2024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2356
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180796
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
9838_WDR73_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.555766
biological_process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10217
A549_Luminespib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186197
SKMEL3	CCLE Cell Line Gene Expression Profiles	-1.0	-3.21067
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99579
K562_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200881
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222291
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.51982
hsa-miR-1243	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2724
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10427
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	2.18458
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967338
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97257
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886598
DU4475	DepMap CRISPR Gene Dependency	1.0	2.529
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99077411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21105
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.973538
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.44571
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
modulates	GeneRIF Biological Term Annotations	1.0	null
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991848
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10989
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75114
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23578
hsa-miR-4670-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159148
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137803
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19779
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061511
K562_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167587
A549_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180526
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18253
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1436
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.767138
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167362
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.73756
BACH1	ENCODE Transcription Factor Targets	1.0	null
intermediate white layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06863
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04612
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14321
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SKMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42336
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
BRD-K26459891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25447
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94837
hsa-miR-3123	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
NR2C2	ENCODE Transcription Factor Targets	1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50161
collicular (rostral) midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0092
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068212
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98598
PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20692
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16798
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24874
BRD-K31010207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28452
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17922
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148631
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-0.977008
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431077
NCIH727	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7404
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214576
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rhinovirus infection_Nose_GSE11348	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54734
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05426
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921661
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865119
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52774
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56476
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921661
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.01
scopolamine N-oxide-6335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198409
A549_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187317
K562_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132525
GTEX-VJWN-0626-SM-3NMAN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00043
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22526
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12226
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nih-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43146
BRD-K78009480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25974
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.02077
actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32173
growth	GO Biological Process Annotations 2015	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0253722
NCIH1734	CCLE Cell Line Gene CNV Profiles	1.0	1.36671
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41656340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12863
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1712
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K87205390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04791
hsa-miR-3618	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
RCM-1	GDSC Cell Line Gene Expression Profiles	1.0	1.95393
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28539
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232682
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
PEO4	DepMap CRISPR Gene Dependency	1.0	3.90057
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENOX1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36164
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25882
RUNX2	ChEA Transcription Factor Targets	1.0	null
A549_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183229
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3925-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
MCF7_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176932
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56682
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K72501910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08029
Perturb_1790_KO_Zfp36l1/Zfp36l2_SRP070761	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74235
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5507
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73701301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56578
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0245661
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155086
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	3.32444
extracellular space	GO Cellular Component Annotations 2015	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
changes	GeneRIF Biological Term Annotations	1.0	null
rnf2_21051595_92dot1_lof_human_gpl10558_gse24896	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.040128
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32168
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00645
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930083
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
BL342 (MEN1)	NURSA Protein Complexes	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11207
K562_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0257824
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246369
A549_JQ1_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134694
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181228
AG-013608-6400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57498440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65419
KIS	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
LUDLU1	CCLE Cell Line Gene Expression Profiles	1.0	1.7951
external side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sphingosine1phosphate	GeneRIF Biological Term Annotations	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.718
A549_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187425
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36515
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834547
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49167
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133688
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01566
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65793
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868707
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07444
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11262
CHD2_02_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60469
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28635
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27044
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3103
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05359
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899501
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174692
BRD-K26738018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28641
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99220724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29758
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49679
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880275
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840774
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21291
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
10061_ZEB2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549538
DDX41	Pathway Commons Protein-Protein Interactions	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81603
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26344
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03069
valproic acid-4433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A17120244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22998
K562_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198068
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147636
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980579
K562_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201134
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45751
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71085
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837601
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486326
Nucleotide-binding alpha-beta plait domain	InterPro Predicted Protein Domain Annotations	1.0	null
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75172
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24031
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46264
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15152
A549_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140307
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.30344
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20067
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATM_KD_GSE54268_662_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
K562_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163038
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084477
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42736
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24837
MCF7_2-Methoxyestradiol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134793
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.793126
KMRC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62456
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213129
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24695
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20843
PMM1	Pathway Commons Protein-Protein Interactions	1.0	null
protein-kinase-c	Phosphosite Textmining Biological Term Annotations	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30035
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80369
endometrial stromal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.802795
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A67508925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02999
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31585
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03636
MCF7_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118024
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.86565
BRD-K90231936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3382
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10367
TRIM28	ENCODE Transcription Factor Targets	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21393
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34347
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24832
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	COSMIC Cell Line Gene Mutation Profiles	1.0	null
13_AARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.527691
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847806
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44861
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824771
MCF7_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0256451
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871386
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18129
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.83568
K562_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154444
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42886
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2547
shrna	GeneRIF Biological Term Annotations	1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
BV173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47062
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29055
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28566
sulfathiazole-1963	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
concerted	GeneRIF Biological Term Annotations	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42813
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	2.27988
BRD-K52104866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01726
Urothelial carcinoma_Urothelium_GSE3167	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.70297
ATR_knockdown_120_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85751
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875855
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17702
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.1378
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.23811
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
procarbazine-2971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disulfide oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
A172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90546
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.71448
MCF7_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142458
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6612
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45384
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67007
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10586
tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.478813
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28687
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20708
Ncnc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3443
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.13734
K562_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0276105
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81282
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989743
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	2.14453
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39284
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U87	BioGPS Cell Line Gene Expression Profiles	1.0	1.29394
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-659	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.11063
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31801624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27231
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34275
K562_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248492
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.9646
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25227
MCF7_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187518
859_BMS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.65373
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207161
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062117
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60716223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1667
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
6603-0104	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
levopropoxyphene-2980	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859563
T-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93272
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937591
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68683
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24736
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125395
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8946
K562_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152899
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3265
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853551
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993242
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K19020285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31642
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
relationship	GeneRIF Biological Term Annotations	1.0	null
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04283
MCF7_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0306174
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10404_KO_Mettl14_SRP123442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.09691
migration	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8764
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35613
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.36259
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57632
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1255
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159516
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04719
HIPK2_knockdown_106_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.17382
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25774
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30399
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3066
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849482
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
BRD-K61287439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43215
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00851
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44851
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
PRC_DEPLETION_GDS3532_96_human_U2OS cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF7_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145038
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
BRD-K93101873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30746
DHCR7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80198
Olaparib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
NCI-H2141	GDSC Cell Line Gene Expression Profiles	1.0	2.40792
GTEX-S3XE-0826-SM-4AD4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894041
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12256
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95684
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25016
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14284
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824992
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26702
ethambutol-1981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRT9	Pathway Commons Protein-Protein Interactions	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28311
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Estrone sulfate (potassium)_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00687321
Tongue cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
GSE137144_3_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74335
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00203
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71458
33B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
TUR	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48677
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27809
BRD-K33098168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06244
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.688481
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17152
INTS5	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136003
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19738
GSE73628_1_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	1.81303
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7483
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906917
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128995
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.722886
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84598
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43486
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.224196
KML1	DepMap CRISPR Gene Dependency	1.0	2.34648
NUP93	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08442552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0522
LB2518-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.41822
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32129
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transformed	GeneRIF Biological Term Annotations	1.0	null
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19606
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RFX5	ENCODE Transcription Factor Targets	1.0	null
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41315
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09081
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13143
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10293
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27124
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.981
demonstrate	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895381
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17093
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18925
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08227
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78619
rhythmic process	GO Biological Process Annotations 2015	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847665
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56393
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12873
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03151
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06622
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255754
BRD-K20271744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03361
tamoxifen_homo sapiens_gpl6480_gse12665	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31307
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0234585
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.27576
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00774
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1121
SETDB1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.569479
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01207
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAG3_Mutation (R225Q)_GSE4067_390_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75902
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10695
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33984
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38345
K562_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015794
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
K562_TGX-221_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195193
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04149
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09297
JVM3	DepMap CRISPR Gene Dependency	1.0	14.6988
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69598
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42962
BRD-K87926172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30462
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869541
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62211
BRD-K38493972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07719
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23291
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496092
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08519
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8994
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32574
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61541
migration	GeneRIF Biological Term Annotations	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49148
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079429
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180047
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K93459372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48334
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12893_KD_ARID2_SRP185722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215653
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97877
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47805
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64139
hsa-miR-4771	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7293
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31748
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09442
1840_CPSF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.718126
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66075
Superior colliculus, motor related, intermediate white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38278
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A77907596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73133
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
acetazolamide-7461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.81115
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55249
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934008
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73376409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47056
TGFBR1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892904
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04974
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08384
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26553
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43822
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	2.45444
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3213
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32769
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24638
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44431
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293151
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64396
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72252
K562_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0387437
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153426
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840551
JHUEM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50658
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06806
GTEX-S4Z8-1726-SM-3K2AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01023
carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
A549_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143342
K562_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145735
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51142
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142809
MCF7_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0245435
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33623
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17143
Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.5549
K562_Capecitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183456
ACCMESO1	DepMap CRISPR Gene Dependency	1.0	4.22595
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982014
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09136
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58057
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29582
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.891397
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08046
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13451
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32011
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.287
amiloride-1970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2598
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0302136
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51825
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970066
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00281
A549_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193351
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37504
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03141
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952779
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05925
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3826
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63073
K562_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136513
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844737
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-A40022950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6695
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
K562_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272523
SLC16A3	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25524
A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80767
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14911
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL1348080	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0319687
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82619993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17989
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30433
JUN	ENCODE Transcription Factor Targets	1.0	null
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30491
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13992
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-421	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30262
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.959488
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.36347
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0264299
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58626
BRD-K60460300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21311
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_M344_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114518
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84079
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	1.56208
8004_SLC25A39_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520036
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48711
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934076
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87685
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05333
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4525
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837216
MCF7_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220926
FOXA1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61749
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5049
A549_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100337
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82521
BRD-K18307373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43641
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17013
GABP-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
water	GeneRIF Biological Term Annotations	1.0	null
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38424
formation	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.32015
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P03206	Virus MINT Protein-Viral Protein Interactions	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.226499
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14182
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UTP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22056
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938065
BRD-K33653343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10601
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19458
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07289
oxaprozin-4530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.991598
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.21777
OAW42	DepMap CRISPR Gene Dependency	1.0	2.88045
MCF7_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119154
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.91362
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06335
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24669989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24957
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K93663012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1279
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61098
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38887
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08288
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70779
K562_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182776
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26007
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37354
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84402
BRD-K86716312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03022
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2825-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.61444
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894033
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78746
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49764
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32754
stressinduced	GeneRIF Biological Term Annotations	1.0	null
ZNF300	Pathway Commons Protein-Protein Interactions	1.0	null
DHX33	Pathway Commons Protein-Protein Interactions	1.0	null
anticancer	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41468
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10681
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49461
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.44419
pioglitazone-5925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7073
result	GeneRIF Biological Term Annotations	1.0	null
K562_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016448
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157151
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.44213
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39005
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54778
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914601
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21194
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.75
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864763
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
chlorpropamide-1594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRE-269	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
intracellular part	GO Cellular Component Annotations 2015	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24369
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57149
SNU449	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16673
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71847
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.976922
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73204
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.900525
MCF7_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161543
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30755
MYO1C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90548911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16319
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.52762
K562_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196202
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171163
Hypertrophy	CTD Gene-Disease Associations	1.0	1.15933
Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87402
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134766
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24475
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88761
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07769
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896962
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30456
BRD-K76742876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92264
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897972
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.852466
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.30238
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
A549_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170596
K562_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0304356
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4461
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52727
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.508667
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.4746
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0575
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AHCTF1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibited	GeneRIF Biological Term Annotations	1.0	null
K562_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159706
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47495
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993313
alvespimycin-4437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43417
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849854
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39959
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075689
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09187
BRD-K92311828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22956
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12791
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47828
A549_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185101
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969611
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3978	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
PMC9932992-mmc7.xlsx-S6D-Table_S6D_Per-gene_per-sample_AR_data_LCLs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
507_ARL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.8599
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12317
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.661088
Urinary bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868427
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58765
PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17837
BRD-K71755056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12802
Adult Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895916
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997632
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.40296
about	GeneRIF Biological Term Annotations	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897678
PIK3CG_knockdown_96_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77308
Veliparib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
MCF7_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134627
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.589
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25336
17823660-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052821
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2356
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
biological	GeneRIF Biological Term Annotations	1.0	null
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.6581
FUS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981455
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14935
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279814
12096084-Figure3-2	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.24801
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45616
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4436b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.03433
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nialamide-4525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148404
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83232
MCF7_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00950099
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
tanespimycin-5958	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KL-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14374
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08308
BRD-K35472285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47366
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27214
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66432757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23369
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29517
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.391
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.941336
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08098
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31389
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84661
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.321594
NCIH2172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10631
Inflammation	CTD Gene-Disease Associations	1.0	1.50043
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.73266
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2402
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.44713
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28547
HS683	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2345
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12805
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBED4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type 2 diabetes mellitus_Muscle tissue_GSE12643	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.67079
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826977
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.65198
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02024
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7243-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tetracaine-1739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94102
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827675
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169244
reaches	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977031
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HIPK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
endometrial stromal sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.805667
prosurvival	GeneRIF Biological Term Annotations	1.0	null
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28073
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216169
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4711-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148831
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903536
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9392
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0116386
SNU466	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55238
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14186
K562_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177712
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869303
Superior colliculus, motor related, intermediate gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.541
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.52891
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.502177
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16895
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Microsporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176583
hsa-miR-193b-3p	MiRTarBase microRNA Targets	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31966
PAX7	MSigDB Cancer Gene Co-expression Modules	1.0	null
K562_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182403
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.82585
BL4774 (MTOR)	NURSA Protein Complexes	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09442
hsa-miR-4719	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06697
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23301
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0159
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849721
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27257
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reduction	GeneRIF Biological Term Annotations	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364331
COLO-679	GDSC Cell Line Gene Expression Profiles	1.0	1.57246
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K26074237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28115
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.101694
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4672
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.10119
BRD-K93615384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25707
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.75013
eticlopride-4634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868629
Perturb_8071_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24124
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.06391
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-0426-SM-3MJH3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56029
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01586
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.18318
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12486367-Supplementary_Data2.pdf-19-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
DYRK1B	Kinase Library Serine Threonine Kinome Atlas	1.0	null
a-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7554-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4003
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5732738-oncotarget-08-103415-s002.xlsx-MFC-7_DEGs-Genes_with_significantly_different_expression_between_parental_MCF-7_and_GATA3_WT_clones_with_adjusted_P_value_0_05_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99470595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0424
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50897
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21611
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
citiolone-6031	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071344
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14354
IRF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018144
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24084
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52335
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87414
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27305
cascade	GeneRIF Biological Term Annotations	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895246
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81726
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29542
MCF7_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177999
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939302
BRD-K83845379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15741
SARS-BatSRBD_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6921
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05142
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VI-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_XAV-939_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0215878
MOK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16123
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74657
Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00206
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13167
lower basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07507
epiandrosterone-4626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1029
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17313
Ebolavirus(ZEBOV)_1hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34396
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	1.54884
BRD-K40361885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02741
A549_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140497
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32189
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27816
K562_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159498
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HS-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14656_KD_LINC00673_SRP102315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
K562_Entacapone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203776
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8497
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04536
PMC10828394-41698_2024_509_MOESM1_ESM.pdf-56-ELF2_ELF2	Rummagene Transcription Factor Associations 2026	1.0	null
tetrahydroalstonine-1756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49743
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51904
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847665
intermediate gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87859
brinzolamide-1615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70643
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24433
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lomefloxacin-4745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186494
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	1.65613
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93082
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051413
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.992304
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836677
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995869
16533762-Table1	GeneSigDB Published Gene Signatures	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96183
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56788
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lactobionic acid-4950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913194
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01937
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04219
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	2.62123
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07648
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71277
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00145
A549_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138493
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153537
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999779
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.95612
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1064
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.32553
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12158
MCF7_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120471
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04757
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32182
CBX3	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19929
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00715
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Raltitrexed_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148167
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.39026
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64553
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224399
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887104
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0652
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09789
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4185
external side of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119065
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48263
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
HEC116	DepMap CRISPR Gene Dependency	1.0	3.65027
MCF7_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213144
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4434
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25864
hela-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29857
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07066
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57172
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-3.16437
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75643
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72667
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928812
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA processing(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Motesanib Diphosphate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175417
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31337291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11625
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87538
skeletal muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.360764
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41333
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90365
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hESC_Derived_CD184+_Endoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03613
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	3.1841
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.007
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16148
UT-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0449
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.940147
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47691
A549_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152267
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25877330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00691
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97742
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thioridazine-417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933434
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953979
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895733
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203038
MCF7_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140162
BRD-K83966071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04456
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27632
regulation of growth	GO Biological Process Annotations 2015	1.0	null
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02507
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NUP205	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0701
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13543
BRD-K40088786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55283
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978994
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832336
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33034
suggesting	GeneRIF Biological Term Annotations	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168402
K562_Tozasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184832
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
PGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835938
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRPK2	Pathway Commons Protein-Protein Interactions	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09027
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93772
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.983967
MCF7_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143609
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148899
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06085
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10007
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997196
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07941
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KD	DepMap CRISPR Gene Dependency	1.0	2.7467
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00036
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43688
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092021
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	0.892931
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15593
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82403
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28742
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76943
BRD-K53617314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06903
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17035
HEC251	DepMap CRISPR Gene Dependency	1.0	3.7419
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00762
pkcdelta	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE138815,GSE138817_0_v_1_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHEMBL2172374	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
MCF7_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158641
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26913
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
K562_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258447
Perturb_17554_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
apoptotic	GeneRIF Biological Term Annotations	1.0	null
ovary	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200652
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44431
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31951
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073785
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062902
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6407
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8312
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838407
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Baricitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154981
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
edrophonium chloride-1519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242004
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9583
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162627
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15944
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52832
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGEA11	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40408
jr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
GSE116299_6_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09202
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260174
SAS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13518
Perturb_2033_KO_Chd4_SRP193857	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1366
8232_SNRPF_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.671327
A549_Nintedanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109503
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1821
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71284
A549_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.030301
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40265664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12707
mantle zone of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56822
EGR1	ChEA Transcription Factor Targets	1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856634
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
proliferation	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43818
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4995-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28262
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
protein complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11876
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45583
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HEC1B	DepMap CRISPR Gene Dependency	1.0	2.30253
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2107
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4887
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-DLX3_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K02563170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5497
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21086
BRD-K94580242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0421
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00136
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3514
CREB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19267
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28838
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34421
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PANC-08-13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44081
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8673
PARP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35153
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933071
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993813
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.937011
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.179
colliculus superior	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56822
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2465
DG-75 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46618
SKNFI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82842
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96263
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.13095
BRD-K67859584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42259
MCF7_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231151
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28002
age	GeneRIF Biological Term Annotations	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21805
K562_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0372571
BRD-K21838437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02871
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38955
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42664
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00614
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35734
MAGEA9	MSigDB Cancer Gene Co-expression Modules	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07367
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51089
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56326
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68468
hsa-miR-512-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981666
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67882
Perturb_16423_KD_AUF1_SRP224925	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64443
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-300-ZNF668_ZNF668	Rummagene Transcription Factor Associations 2026	1.0	null
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34924
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90997
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053403
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1303	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04381
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07764
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950476
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.184
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51081
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76993
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HuCCT1	GDSC Cell Line Gene Expression Profiles	1.0	1.88113
BRD-K27178862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05168
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14603
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09037
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19852
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7989
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94959
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46992
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32783
GPD2	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
capsaicin	GeneRIF Biological Term Annotations	1.0	null
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47123
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3371315-NIHMS350140-supplement-13.xls-MCF7-T47D-SK-453_Up_Common_xls-Supplementary_Table_6_Luminal_Signature_Genes_increased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.897495
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31862
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219925
hexamethonium bromide-1982	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10357
BRD-K20735575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08749
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36323
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09143
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15175
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22122
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
LM-1685-207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NOLC1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.462798
CP67-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.56801
K562_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153238
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.86581
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974762
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03823
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16735
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11979
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	2.94131
tridihexethyl-5486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71788
A549_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137599
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.39687
A549_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178488
PMC10809641-DataSheet3.pdf-115-EMX2_EMX2	Rummagene Transcription Factor Associations 2026	1.0	null
EFO21	CCLE Cell Line Gene Expression Profiles	1.0	1.43099
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66689
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73063
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2906
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.13946
AP1S2	ChEA Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982607
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196526
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997118
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60116
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0233023
DYRK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73529
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110855
K562_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152088
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05626
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16279
HSPA6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular	GeneRIF Biological Term Annotations	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19466
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25478
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.75704
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58007
K562_XAV-939_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166163
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02839
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
GPAM	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12348
BRD-K51490423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36181
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56275
enzyme	GeneRIF Biological Term Annotations	1.0	null
Spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.363
K562_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167303
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938167
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAPK14_knockdown_139_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.63249
MCF7_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137944
sulfaguanidine-1995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63461
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
AGPAT5	Pathway Commons Protein-Protein Interactions	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848371
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25782
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	2.36554
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21929
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
hsa-miR-450b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11557
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39383
RAD21	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73863
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32835
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.273367
TMEM33	Pathway Commons Protein-Protein Interactions	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964333
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4079
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838362
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04832
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15869
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26294
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02146
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951487
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0415
SYK_druginhibition_155_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.69596
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24642
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918996
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537731
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39961
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2564
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26322
hela	GeneRIF Biological Term Annotations	1.0	null
nadh	GeneRIF Biological Term Annotations	1.0	null
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968616
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970855
BRD-K30221348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4371
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Tazemetostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158194
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sufficient	GeneRIF Biological Term Annotations	1.0	null
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.932
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
hsa-miR-3160-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6111
A549_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186532
A549_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014515
loracarbef-5492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05998
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32874
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.90731
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.98248
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72203
A549_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129807
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-507-THAP10_THAP10	Rummagene Transcription Factor Associations 2026	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K91998226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02749
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47346
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73609
K562_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164465
K562_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137974
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06163
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832367
BRD-K13241788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21802
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9543
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53873
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72151
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19871
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43512
GSK3B_KD_GDS4305_181_human_MOLM-14 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270324
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095679
NCI-H1693	GDSC Cell Line Gene Expression Profiles	-1.0	-2.10872
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92617
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29689
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460692
BRD-A30547447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16549
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42459
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19821
CLASP1	Pathway Commons Protein-Protein Interactions	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279307
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040543
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964765
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22199
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155586
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15587
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82684
A549_Selisistat_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012176
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.35605
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A549_Pracinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00970271
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5552
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93941
uterus	GTEx Tissue Gene Expression Profiles	1.0	1.02136
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
chrX_130595667_G_A_b38	GTEx eQTL 2025	1.0	1.00094
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26634
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28068
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09301
NB10	DepMap CRISPR Gene Dependency	1.0	8.60141
MCF7_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0111305
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5054
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02196
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.61573
MCF7_Navitoclax_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013531
SF-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
hMPV_12Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91475
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08066
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214204
A549_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155335
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02296
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.898045
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.20097
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.71724
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07208
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ubiquinol	GeneRIF Biological Term Annotations	1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.807
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36285
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13431
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54549
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.23777
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.47993
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRO-AP2	GDSC Cell Line Gene Expression Profiles	1.0	2.124
meclofenoxate-4729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5712
cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.615529
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864763
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1102
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95036
karakoline-4763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adermatoglyphia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
hsa-miR-623	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MCF7_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108624
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
enox2	GeneRIF Biological Term Annotations	1.0	null
WRN	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9157
mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276495
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2216
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139004
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5529
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16141
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1765
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38608
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26387
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Trametinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100258
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46087
troglitazone-4456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7267
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVE127	DepMap CRISPR Gene Dependency	1.0	2.15487
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17422
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79552
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74761
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5009_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.71245
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54643
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71312
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.82224
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7129-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0857
BRD-K15174326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28286
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36359
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882193
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119323
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05528
BRD-K67200393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1772
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50371
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55492
amantadine-4806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31409
A549_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114385
MAZ	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00329
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87319
directs	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.32098
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057936
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
amphotericin B-3303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TNXB	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06731
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62618
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055672
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01209
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51822
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47377
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33347
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29191
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906493
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053846
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59136
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055862
MCF7_Carmofur_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126989
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91225366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61124
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.17268
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860135
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
1941_CTPS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.3185
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45309
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.34459
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135751
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152491
K562_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153202
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128216
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
BRD-K56801250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77155
Perturb_17553_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7532
K562_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132162
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1561
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18644
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K08308527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88168
K562_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143133
BRD-K18864235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04705
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
guanabenz-4642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98401
GTF2B	ENCODE Transcription Factor Targets	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heavy chain immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BA/F3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
A549_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203382
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27998
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26672
10828_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.501387
CRCGN015_MCF10A_48H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25568
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886903
BRD-A40504327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0044
SUDHL10	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.91909
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
K562_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146231
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06017
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886327
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.919518
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27708
GSE151782_6_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE5370	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.24525
A549_JNJ-7706621_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125214
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71863
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89664
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64079
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pirinixic acid-368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173728
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14956
RCCFG2	DepMap CRISPR Gene Dependency	1.0	3.74075
K562_UNC0631_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166744
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01594
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964492
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886742
A549_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014771
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
cervical adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.820026
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04395
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A459-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170903
CDK3_knockdown_110_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.19894
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892352
COLO205	DepMap CRISPR Gene Dependency	1.0	2.10551
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08194
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252233
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11512
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121235
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.014031
MCF7_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112114
Perturb_62_KD_Ccnt2_SRP312148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.33208
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10835
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80271
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Malignant Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18523456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08116
RF9	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2041
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18151
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VJYA-0226-SM-4KL1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828207
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150679
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.855879
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06177900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51097
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HEK 293T	BioGPS Cell Line Gene Expression Profiles	1.0	1.42928
antisense	GeneRIF Biological Term Annotations	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
aging	GeneRIF Biological Term Annotations	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14926
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4450	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74973
MCF7_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014649
inhibitorinduced	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4644
clozapine-416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.04617
ZC3H11A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77659
SIX5	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43619
K562_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182363
muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.286877
Malignant mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
BRD-A99402294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01752
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07064
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08826
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68762
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223112
zidovudine-3211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1231
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K53127431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24727
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16562
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21854
STT3A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BL1550 (HIPK2)	NURSA Protein Complexes	1.0	null
A549_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168051
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09994
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17061
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0357
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23915
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
KRT1	Pathway Commons Protein-Protein Interactions	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5312
pimozide-1562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08789
hsa-miR-4753-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MCF7_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126803
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21163
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08194
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938968
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836267
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01325
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21734
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06788
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79109
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965223
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.702
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144118
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08966
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016135
diltiazem-1948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78865
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55002
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950188
MCF7_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174125
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20303
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16303
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
3t3-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1288
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37472
chlorhexidine-1525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4642	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Perturb_1834_KO_Ogt_SRP250299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3585
MCF7_Clevudine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192766
LRRK2_activemutant_159_GSE36321	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.17127
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851191
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5786
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8037
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE190950_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
oxidative	GeneRIF Biological Term Annotations	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4740-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K63212062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08563
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937224
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00896
MCF7_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132358
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25988
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32259
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
meropenem-5824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997389
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82992
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912678
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184036
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49147
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58412301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18986
HLTF	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20706
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03998
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849854
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K46126513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04624
A549_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017893
BRD-K86951121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04711
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17005
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.785104
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91794
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23724
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907497
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49483
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4329
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5113
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
K562_UNC0379_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229433
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13368
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
BRD-A99687212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48309
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49262
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942741
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47601
BRD-K04631545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36093
TBP	ENCODE Transcription Factor Targets	1.0	null
BRD-K31001397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11601
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.77774
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1755	CCLE Cell Line Gene Expression Profiles	1.0	1.35189
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174999
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3743
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.14709
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21816
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19664
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
2785_EXOC8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553854
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02104
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18795
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214134
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837179
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28191
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25923
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846496
BRD-K36376229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39689
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56995
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10607
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-876-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085298
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.958154
A498	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20047
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056559
oligonucleotides	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55716
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62258
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178345
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29601
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872519
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.26183
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59997
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19394
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21908
Perturb_9655_KD_IRX4_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.448
BRD-K15992638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4802
MXI1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32913
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875116
A549_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158798
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39815
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28804
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07554
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17486_KO_Otub2_SRP314435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.40309
transfection	GeneRIF Biological Term Annotations	1.0	null
iloprost-488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A5-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCRCW	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5581
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.613
BRD-K83300227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39478
MCF7_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147857
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07916
form	GeneRIF Biological Term Annotations	1.0	null
A549_Mocetinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147029
transfers	GeneRIF Biological Term Annotations	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5147
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93132
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29235
NCIH841	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74719
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966698
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1582
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68086
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.964438
MCF7_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128544
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982551
BRD-K96945047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03261
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75279
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45741
K562_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144997
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88837
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46716
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07153
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L3MBTL3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.503
MCF7_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218259
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27694
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMPD4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27468
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32564
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.39458
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52352
K562_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.026071
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Nasopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.97393
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
males	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07337
RB1	Pathway Commons Protein-Protein Interactions	1.0	null
variant	GeneRIF Biological Term Annotations	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174655
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
1458_CDT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542151
Perturb_1975_KO_Ogt_SRP250299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.219
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.2842
HS-SY-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18429
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27523
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
TRIM23	Pathway Commons Protein-Protein Interactions	1.0	null
cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.561004
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2296
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1974
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.20155
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6246
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCD	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40641
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99089
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43548
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34692
A549_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194418
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838375
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06043
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863254
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13234
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
where	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60181
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594451
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.45695
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36836
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169909
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45784
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94855649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05165
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.20201
reduces	GeneRIF Biological Term Annotations	1.0	null
neurod1_17630985_pineal_gland_lof_mouse_gpl1261_gds3000	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.646074
MAFF	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5001
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921661
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225004
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64076
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874943
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85568
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44445002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29337
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31928
K562_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184166
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28567
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15559
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65752
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018799
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991322
A549_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138321
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04404
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37781
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210642
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953272
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963664
BRD-K75076471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28734
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848412
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.938585
USF2	ENCODE Transcription Factor Targets	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93656
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4395_KD_SUV39H1_SRP290196	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54099984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05961
A549_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148662
ZNF263	ENCODE Transcription Factor Targets	1.0	null
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00492
ultradian rhythm	GO Biological Process Annotations 2015	1.0	null
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45472
CUX1	ChEA Transcription Factor Targets	1.0	null
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64695
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914027
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1291
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K68073004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1022
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16773
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67638
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12106
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.85965
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levonorgestrel-4730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152373
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38761
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60774
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92251
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47309
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864763
hsa-miR-2909	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85466
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36913
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5326
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835545
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09067
activities	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965529
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25782
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45459
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948738
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27028
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604832
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06964
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.8089
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.263
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17741
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06406
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153595
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995869
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59722
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72029
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20824
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09826
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52546
NB17	DepMap CRISPR Gene Dependency	1.0	5.14878
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.02969
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79645
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171134
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42236
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839519
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835735
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7993
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
suggests	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03905
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
maximum	GeneRIF Biological Term Annotations	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34802
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC27A4	Pathway Commons Protein-Protein Interactions	1.0	null
1578_CHML_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.652788
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ovary cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
capable	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06095
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38713
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16065
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73604422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03544
Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85843964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15804
MCF7_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0257496
THRA	MSigDB Cancer Gene Co-expression Modules	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11363
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3354
MCF7_Filgotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0276707
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26184
BRD-K69777784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31274
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF148	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99936
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203-2004(H5N1)_0Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.12801
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851127
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15042
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29576
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01366
Asarone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
pargyline-2102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37052
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Decitabine_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164068
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91079447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22398
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0846
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26488
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92231
Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55718
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1621
GSE202434,GSE202438_7_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00137
A549_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142252
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61507
BRD-K10781609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31936
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38064
K562_Roxadustat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180489
BRD-K91297952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02591
A549_GSK J1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136527
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.02671
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87301
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11216
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898442
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.5035
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64627
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.61452
NCTC-2544 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50943
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56461
NCIH1395	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04039
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81761
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6105
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34225
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910537
chlorpromazine-426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28968
REST	ChEA Transcription Factor Targets	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
9909_XRCC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500189
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13162
MCF7_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155611
9962_ZBED2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.665422
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90777
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15252
MCF7_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126047
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC9	Pathway Commons Protein-Protein Interactions	1.0	null
Fc-alpha receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
required	GeneRIF Biological Term Annotations	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175704
A549_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193422
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60731
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5ND-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63102
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892424
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11008
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00235
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
BRD-K24659381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05694
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969513
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61157
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064872
INTS6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996502
MCF7_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244825
NALOXONAZINE-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08428
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07432
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7256
A549_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181678
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13492
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33893
MCF7_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134127
nocodazole-2239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946723
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4512	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9686
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068248
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54753
SARS-CoV_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.24632
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.78329
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.56468
Paroxetine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
PMC5013636-ncomms12601-s5.xlsx-LEF1-Groups_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4151
BRD-K29331543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09014
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25833
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00863
HIPK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.69396
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125677
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNA recognition motif domain	InterPro Predicted Protein Domain Annotations	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16933
BRD-K43979194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36794
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063361
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828413
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881669
A549_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131899
imatinib-366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27288
hsa-miR-4290	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00566
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10324
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05123
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893478
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20076
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925047
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2493
CEBPZ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-2861	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13904
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08913
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
epigallocatechin gallate	CTD Gene-Chemical Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4566-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.612
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.23626
BRD-K45904718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.18629
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.17629
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14694
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35732
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05903
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.35672
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93066
NFIC	ENCODE Transcription Factor Targets	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Severe COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3339
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0964
MCF7_Tozasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145775
hsa-miR-190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
10-methoxyharmalan-1743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169292
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31328
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5758
K562_SRT2104_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169681
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29385
SC-58125-208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01005
skin	GeneRIF Biological Term Annotations	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
containing	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38373
Perturb_6356_KO_Bcat2_SRP058363	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6578
gibberellic acid-4818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0273936
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52451
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13879
OE33	CCLE Cell Line Gene Expression Profiles	1.0	1.78668
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null