association	dataset	threshold value	standardized value
BRD-K95443593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03693
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28058
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.727
BRD-K38343532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32839
BRD-K14431723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08078
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41451
MCF7_Panobinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00719535
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17485
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.587703
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32608
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79589
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09398
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	240.455
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41655405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30348
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81028
CRCGN014_HEPG2_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17182
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17769
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12653
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04142
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15902
GSE75976_3_v_9_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43221
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9305
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.8272
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3004
CRCGN008_HEPG2_24H:G20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24865
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81438
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35461
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92544320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59557
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88217
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65415
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79014
BRD-K17315445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80324
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50133846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02529
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5526
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29002
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
BRD-K72787967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30726
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24718
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19223
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17888
BRD-K64859133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71435
A549_Trichostatin A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00891952
Delta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24878
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48652
BRD-K56977200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0077
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163236
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02007
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6992
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03066
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09982
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18197
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68036
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3353
BRD-K73858940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36563
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7751
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1236
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73415
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57783
Human - Kidney - L2 - Parietal Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
15q11q13 copy number variation	WikiPathways Pathways 2024	1.0	null
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28448
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6549
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.976
BRD-K64742599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08927
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9322
BRD-K09191014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57234
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10754
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11636255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12299
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12587
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55054
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22420708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20301
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4844
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35502
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48860650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04567
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.07655
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.0456
BRD-K38240683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36243
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.32517
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20771
MCF7_Quisinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00695828
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70504
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2267
A549_Tucidinostat_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.00993128
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39658
CRCGN016_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61172
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.532
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.416
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Abexinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116021
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7662
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28917
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.608
BRD-K25931705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38254
BRD-K40697889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03423
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07935
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05418
GSE145915_3_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4157
BRD-K80336250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06877
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61151
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20172
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.889
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58962
BRD-K46074482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42523
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2734
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07463
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25665
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2468
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
PMC11250262-41588_2024_1798_MOESM4_ESM.xlsx-ST18_665_top_menarche_genes-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.50697
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56024344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07642
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33844
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34912
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00493
BRD-A82843133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20747
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11887
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1766
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7019
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23385
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22285
BRD-K75293299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04203
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55553
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-GeneExpression_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.63365
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04917
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33582
A549_Vandetanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127312
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11528
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28790383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08624
BRD-K42663584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10798
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02168
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69350688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09819
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25637
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08895
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21989
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19196
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2903
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76437403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46665
CRCGN017_MCF10A.WT.HP_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0446
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17862
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Panobinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132961
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9054
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.87679
PMC6766969-PATH-249-90-s006.xlsx-TAB_S2_b-Supplementary_Table_S2_b_Top_100_upregulated_and_downregulated_genes_in_TAF15-NR4A3_vs_EWSR1-NR4A3_engineered_cell_models_NR4A3	Rummagene Transcription Factor Associations 2026	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75923
GSE205976,GSE205978_3_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70163662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17552
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20887
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_WT_KLF4-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06094
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11377
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02305
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02467
BRD-K37588779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50313
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.593302
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88475
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54814515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40222
BRD-K01297681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55268
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3108
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.47455
BRD-K92433833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32242
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69708
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Quisinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143193
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1317
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07286
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4749
BRD-K11342801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59094
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05204
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00579
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.25143
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04116
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.508
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8199
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4715
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38925
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr15_29596474_A_G_b38	GTEx eQTL 2025	1.0	1.1827
BRD-K05535086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02201
BRD-K89650689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17043
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14718
MCF7_Dacinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00552121
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42607
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11606
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.173
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17331
A549_EED226_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141996
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Tucidinostat_A549	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0124577
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29526
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Mocetinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148406
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03342
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60022
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.57926
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.01346
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K65112040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28906
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0007
BRD-K84935293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0161
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.2024
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00165
chr15_29424841_A_G_b38	GTEx eQTL 2025	1.0	1.32713
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.15665
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02877
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99036206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21876
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12928
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37031
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22289
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05048
BRD-A50913845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04765
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.10235
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07111
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1123
BRD-K18428988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77858
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2007
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1226
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29511
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7456
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11787
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
BRD-K69528787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63036
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04714488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25388
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21046
Human - Kidney - L3 - Parietal Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.20072
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1647
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51941
A549_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130215
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05007
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
BRD-K60794504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27926
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10096
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2695
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24938
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48540267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64128
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59266
BRD-K86491317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73625
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55735
BRD-K09295309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61008
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38713368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15459
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.007
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3022
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12776
BRD-K28919392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72602
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00219
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.89284
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02451
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19474
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65748
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	164.855
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80665
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26221
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	186.508
GSE75976_3_v_1_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83875224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10589
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12351
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24896
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
chr15_29543988_G_A_b38	GTEx eQTL 2025	1.0	1.25012
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1758
BRD-K64902833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4835
A549_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125755
BRD-K76620631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15114
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8999
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26865
BRD-K83183132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43566
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32977
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.4613
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25523
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79349
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6006
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_17_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4317
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69796
A549_Givinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120551
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2358
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23291
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00433
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40248932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20154
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.78551
BRD-K47272214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28951
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
Bexarotene_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0158799
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11428309-12920_2024_2011_MOESM1_ESM.pdf-26-PITX1_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40862705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08717
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34754
BRD-K34026318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4367
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
BRD-K80923834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05794
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38881
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28264
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.75023
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46975
PMC11625982-AJH-100-10-s001.pdf-68-ZNF534_ZNF534	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1617
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.38787
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27496
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36488
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16304302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52185
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44595
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6395
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94915822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47229
BRD-K34110797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0407
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64264170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08295
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26128
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8685
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.9532
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52679
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25168
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40658
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2534
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.594
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8142
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21488
BRD-K04092807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29627
BRD-K62541003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01175
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64362
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22118
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.0522
Postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52991
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5503541-oncotarget-08-38399-s003.docx-1-EVX1_EVX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38826
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	2.81358
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82935
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42721
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.372
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60435
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
A549_AR-42_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143952
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0683
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9969
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13273
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.5374
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57175
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4425
BRD-K36352298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68831
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5612
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82764092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39055
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50334
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.021727
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21578
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21219
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aggresome	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.418
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.732
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9236
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63829331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71116
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9156
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_11_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7285
BRD-K44483161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41001
A549_Panobinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014968
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
BRD-K76088420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05808
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26718
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97919
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31922
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3465
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6093
CRCGN014_HEPG2_3H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05632
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27964
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82124
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13831
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23655
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2724
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14613
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82677
A549_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140032
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43178
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67735
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13501
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18835
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05826
CRCGN015_HEPG2_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2184
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6266
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.26406
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	333.916
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78889331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41988
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7014
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25632
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2646
NCI-H1299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
BRD-K16411174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24845
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.15703
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88761
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09545
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04032
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64814
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47323
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14493
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56669
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42629
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2322
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3077
BRD-K48263613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5885
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.689
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6708
BRD-K88395026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15689
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38331
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19917
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44849
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	198.25
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.572
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.82339
BRD-K21936026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34476
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05803
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58324
Postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.53764
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08166
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0948
BRD-K45043387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00053
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.22679
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54879095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28699
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Quisinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197109
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66868536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77768
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.213
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26347
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3425
BRD-K69337311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5931
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47108
GSE131887_1_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2768
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.46335
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19377
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90319
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52372
A549_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120453
BRD-K07245666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26574
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01023
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62082
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49075
BRD-K63645840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12645
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08049
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83902026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9427
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.531
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84766
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25485
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0084
BRD-K62964360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45934
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22869
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K13226207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13533
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2017
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41042
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24006
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17988
Skin pigmentation (conditioned on rs1426654 and rs35397)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_up-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35396
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45941986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11938
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21395
Occipital pole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64789
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Carbidopa (monohydrate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.022507
BRD-K12784613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15237
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40818
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_11_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54898824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46175
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94833531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03689
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24029
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35288606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6997
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8436
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24022
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4573
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113221,GSE113968_4_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3728
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
BRD-K45665532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26139
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80981
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43042
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7606
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0235
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74238
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35539
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16759
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98253383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20879
BRD-K55972185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46529
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76092
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0908
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.916
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49449
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59028
GSE166004_7_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56276074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01478
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.84455
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72403
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53883
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12742
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84315
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00861103
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.16998
PMC9391581-mmc4.xlsx-KLF4_K409Q_vs_GFP-activated-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0717
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71312
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00653723
BRD-K01162126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44153
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1452
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.411
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25109
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6666
BRD-K17020860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48015
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31028
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40822
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56802
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.3581
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24847
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	223.603
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10056
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09137
A549_Luminespib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145796
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.40928
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05507
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1465
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-276-ZBED1_ZBED1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76204
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17583
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60224
BRD-K57365604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56712
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2281
BRD-K32354807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04681
MCF7_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01106
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84269
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41634
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3628
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6029
PMC7988717-NIHMS1674683-supplement-6.xlsx-Peaks-DEGs_with_overlapping_TS_and_intragenic_SOX17_and_ATAC_peaks_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197532,GSE197533_0_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.7918
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5203
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67038
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20956
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25114
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7198
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.45
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19707
Hippocampal mossy fiber to CA3 synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.844
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63272
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29597
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57394
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01517
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33347
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5955
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06813
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0133
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03641
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.83051
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0356
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_CUDC-907_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00887242
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10253
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77586
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.44375
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21581
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.80831
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23935
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111662
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05411
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57201
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12871
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10673
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69827
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
BRD-K69984954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48869
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.7146
BRD-K69147598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26378
BRD-K30285881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50446
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15796
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.16051
BRD-K00846914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10464
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9324
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07384
BRD-K97337407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61759
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Mocetinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102901
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20359
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47825
GSE181959_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63998
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11223
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02179
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23604
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5896
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71905
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A32018906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94512
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4335
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_1_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23983
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.315
BRD-K52154207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.132
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35936801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06323
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0556
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07076
BRD-K57200567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1236
BRD-A65806553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00838
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46757
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83098569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09779
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08957
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20066
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Testis 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	4.26872
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88766
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29475
BRD-K94347944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59924
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209104
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44503
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03961
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04185
BRD-K06310280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4875
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43741
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205556_2_v_0_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1936
BRD-K30883461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02965
BRD-K34069025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20364
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16138
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11274
BRD-K77990919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09842
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_M344_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119293
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89891928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10914
BRD-K43989220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4715
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53282
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48383
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42294
BRD-K39081386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01399
A549_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107994
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2703
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49728
A549_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00929747
BRD-K67592986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67839
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65116
BRD-K61623863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39083
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51576
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7451
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07392
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25565
CRCGN008_HEPG2_24H:D12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1917
BRD-K42453497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10551
BRD-K76723780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12044
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	79.9083
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5029
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07003
BRD-K56075657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52874
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42264
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1572
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23054
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.713
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35216
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34571
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70343553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12889
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55791
BRD-K83567669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16812
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1599
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69277
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00631
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17164
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47118
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04183
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03397
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83235
BRD-K77903467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08238
A549_Abexinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125886
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13683
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30679
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47526
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9372
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1968
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07619
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43121
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07914894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07003
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5171
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29033
BRD-K17885598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05406
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Belinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00743539
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28753
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.004
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22448
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21788
BRD-K57969360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97027
CRCGN008_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4784
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7416
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.45665
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.148
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38132
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54833
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07534805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05534
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38388
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11365
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5991
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.039
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.6807
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06068
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38227
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01850737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34425
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40876208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85118
BRD-A43575461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12422
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inclusion body	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.418
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.02662
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3188
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04348
A549_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012374
CRCGN008_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6171
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16694
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94404
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Retinal pigment epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07087
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66047
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39007
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50087
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13091
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66735566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20728
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18302
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38649
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2195
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8835
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61785
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.303
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04223
BRD-K54262203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17572
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59809
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17648
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63401
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15128
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32245
GSE223008_7_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11046693-pnas.2320938121.sapp.pdf-66-ESX1_ESX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13289
CRCGN011_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4971
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29088
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06418
BRD-K34335352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23715
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41285
GSE196117_6_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54414
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92795658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15426
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47728
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27171
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17508
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68015
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48942
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7489
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.66814
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6277
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17185909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07412
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152228
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75183
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98940411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11273
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19754
BRD-K43271856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02807
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91225366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52995
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22699
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03902789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13426
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.10196
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8933
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34729
GSE211829_9_v_4_tafasitamab_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37141
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27426
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36543
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24542
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3244
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23477
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3325
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_CUDC-907_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00817046
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41614
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58063
BRD-K77540020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46218
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34996
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6836
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16305
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.6082
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.2637
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56294
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02778241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15196
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18439
Human - Motor Cortex - Cross-Species Cluster - Layer 6 glutamatergic neuron, corticothalamic-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.01479
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61818
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.987
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.963
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24669
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-ZNF423_targets-target_gene_ZNF423	Rummagene Transcription Factor Associations 2026	1.0	null
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62999
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.68439
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33526
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3944
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50645
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03761
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71132173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08216
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08676
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31827
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29039
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67936
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01759
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3843
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89837874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58334
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55171585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63987
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05634
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60102
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56841
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31780647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18672
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84775364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14373
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.732
BRD-K31390971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14844
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71905
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2066
BRD-A95207036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0301
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67353973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24245
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30941
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00787
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81921
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.7404
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50496
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.59111
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32995
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04088
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5287
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38653
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06495
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99013
BRD-K87794979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59013
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40233
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13632
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24173
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9453
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0431
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03877
BRD-K09206831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38911
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07614
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17482962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89124
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.6635
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIVF001-021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10063
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	174.346
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.788
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07922
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6467
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03556
GSE152032_0_v_1_s1pr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7049
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25426
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29973
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.58584
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10225
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34944
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.9264
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31965
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21002
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48405
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10674
BRD-K47348275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14025
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null