association	dataset	threshold value	standardized value
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41498330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5492
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28366
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09269
BRD-K57359365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00619
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37767
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78845
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pridinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07065
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42977
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09676
BRD-K20065789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04662
BRD-K70322385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04175
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07923
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
5902_NUP88_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.5519
Brain morphology (min-P)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.91549
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99695
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44586
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47953
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2263
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	218.069
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1537
BRD-K77407030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36095
BRD-K67082570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82097
Regulation of mRNA processing and protein ubiquitination	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K17979415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78868
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.778
BRD-K03205303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11829
GSE136591_0_v_1_akap11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23749
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10361959-41419_2023_5985_MOESM1_ESM.pdf-933-ZNF496_ZNF496	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02489
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22197
BRD-K75738997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43233
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77392050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65348
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_PF-573228_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153759
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adventurousness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.16788
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5102
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00526
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93561942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01098
BRD-K61868194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6607
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6723
BRD-K05657319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64896
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16192
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87995704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54907
GSE143643,GSE143644_1_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kibra-Ex-Mer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_HepG2_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.58545
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-SE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45731
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49798
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08178
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2089
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76449854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.768
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.553
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97318603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2277
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27903
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74235
BRD-K79379353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31024
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07291
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18443
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
External iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15803157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07579
BRD-K21819164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89912
BRD-K65663356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39005
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80196706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60774
BRD-K50498614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55565
lb7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.95577
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22313
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06225
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06164
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38343
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06449
BRD-K03512847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42998
507_ARL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565773
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34068
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4367
BRD-A67254212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38324
BRD-K38604123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25611
PMC5640240-ppat.1006668.s013.xlsx-BETA4-379_common_elements_in_shEP400-1_BETA_shEP400-3_BETA_shMYCL_BETA_and_shEP400-2_BETA_BHLHE23	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10419
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71496240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75259
BRD-K81537454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16502
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40049
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40014
BRD-K52532740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17438
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7525
GSE89018_1_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5601
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64748
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4554
BRD-K05220907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03244
BRD-K62935726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81401
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76215
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40475
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05099
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3965
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.978
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.06439
BRD-K66494817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53853
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40188
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5741
BRD-K01045229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28469
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04373
LM3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.432
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74632893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.097
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.24408
1458_CDT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.592559
BRD-K60017729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79895
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0002
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10534007-Table_3.xlsx-S7_unique_up_MSC_V_2-312_elements_included_exclusively_in_VMCUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K80739863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39361
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92607
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22605
BRD-K77824583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.78292
GSE158834_11_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09721398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42529
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19245
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98242
GSE158834_11_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Target_Genes-Gene_ID_s_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16557
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05969
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71495
BRD-K78403457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18306
9738_VPS13A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.564967
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12914
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K53168433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00808
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A15798299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38079
BL-41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07238
BRD-K31483891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50763
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50458
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64642
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03539
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65783
BRD-K61517058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45406
PMC9164468-13073_2022_1056_MOESM1_ESM.xlsx-S7_ARNT_alteration-Gene_ID_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41113
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25187
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lb23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
BRD-K61698250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2424
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11623
BRD-K73048554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36281
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.703806
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.021
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21811
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.39441
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26276
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0011
CRCGN011_HEPG2_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04598
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25287
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95871937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56688
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15453
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56502
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.5963
BRD-K70558130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0017
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical thickness (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.60969
BOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19253
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19282
BRD-K37741838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91798
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77786
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9917
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.05022
BRD-K72098698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20931
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72255288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64454
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7553
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00763
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620557
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1783
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K18532833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40616
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74908937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98799
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39078753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76028
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1459
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27685
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55109
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76309489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46425
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Protein quality control and ubiquitin-proteasome system regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59913416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48758
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vs86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68178119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82474
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34606
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89175823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21057
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77023
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13909
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20049
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5017
Cortical surface area (min-P)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1702
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20083
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34607
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31335
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26671
GSE113734_3_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6241
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
micropexophagy-specific membrane apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66999
BRD-K69515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06279
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51196
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0605
9667_USP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.544377
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70108
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62358193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64246
BRD-K44894536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14532
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08189
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34085
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76389813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.06379
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03897
BRD-K32240435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2601
GSE210990,GSE211030_3_v_2_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16439
BRD-K64347765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25025
BRD-K90048234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40856
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32679
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00926
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91011
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1264
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Binding_Sites-Egr1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78955
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04143779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08828
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2443
BRD-K74933734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01812
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21105
BRD-K02747732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31003
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23208
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48561
PMC4521181-oncsis201520x8.pdf-41-ZNF654_ZNF654	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1096
BRD-K39271757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50383
BRD-K78530095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38475
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC1S4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07144
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76995
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75413
BRD-K33037101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62656
714_AURKA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.521817
Coronary atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE56235_1_v_0_prdm11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92589_2_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE62843,GSE64370_4_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07213
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53865
PMC3470785-NIHMS377161-supplement-3.pdf-98-TERF2_TERF2	Rummagene Transcription Factor Associations 2026	1.0	null
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03707
GSE231891_1_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31737
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.655
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.2356
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Scapula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stinger	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5093
PMC2768459-6605275x5.xls-Hoja1-Supplementary_Table_S2_Differentially_expressed_genes_within_the_ESR1-negative_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37556799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54237
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22405
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5437
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24199
BRD-K41717398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39342
BRD-K84690141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18993
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0329
7463_RPL35_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642053
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19734887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05109
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.577
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
3633_HAT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.602863
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85241
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24492
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66857
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8972054-MSB-18-e10682-s011.xlsx-Dataset_EV4-THAP3_THAP3	Rummagene Transcription Factor Associations 2026	1.0	null
Interstitial cell of Cajal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15742
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36527
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.61438
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11923960-ADVS-12-2411131-s001.pdf-11-ZNF436_ZNF436	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Median body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44102
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84178323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76326
BRD-K51525251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26397
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dg1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Body fat distribution (leg fat ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76067434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76275
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09724
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8384902-mmc2.xlsx-3_ASCL1_high_subtype-Gene_Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77223020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83024
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7449
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38414
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45752
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.44462
BRD-K54621976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15747
Neural arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
BRD-K14942405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22119
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52185
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62708569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21848
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42772
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
BRD-K03851221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66893
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76558091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48608
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cephaeline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56393
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45592944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67976
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22832
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nizatidin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06775
BRD-K23547378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51937
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.96
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23798
BRD-K06226868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60304
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28761
GSE87144_3_v_1_rorc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.64626
BRD-K75900642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43677
BRD-K78500251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24081
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41504
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19336
BRD-K80298486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95941
GSE178714_5_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6137
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36439
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3742
BRD-K27782186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24995
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10550956-41467_2023_41912_MOESM4_ESM.xlsx-Supplementary_Data_8-Supplementary_Data_8_MR_and_colocalization_analysis_for_gene_expression_in_whole_blood_and_COVID-19_outcomes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65005022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66089
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76999
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11611
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.553
BRD-K59522787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50345
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0443
BRD-K75275329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07688
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9858
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7472
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80113
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86848211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42327
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07438795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51778
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83919473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05489
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GAIT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
BRD-K71391283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8685
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28619
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_5_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34579
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74522958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13938
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19267
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0606
Prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-IRF1-HIT_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53812
PMC3712200-584604.f1.pdf-59-CREB3L4_CREB3L4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25185158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37655
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34314
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.27536
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18078
Df	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51317
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58177
BRD-K77869482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48913
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17321
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.553
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17654
Subcortical volume (min-P)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.904576
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63209730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59987
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14207150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09262
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82077
BRD-A39506880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18262
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0984
BRD-K50604515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13046
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26435
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02334683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51573
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55675
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7641
BRD-K63330804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42668
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74674
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32319
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39011
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77108448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80173
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
BRD-K25649596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6063
BRD-K62312047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69265
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76976010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14777
lb24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63960902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03123
BRD-K60653414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30999
bp96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.927
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92565319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2805
BRD-K20897375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49836
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13101
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34501072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40302
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.66145
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55623
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161842_1_v_2_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37719063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10235
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31677
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74129999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08344
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9676
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4728380-ncomms10153-s11.xlsx-Seitz_Burkitt-SEITZ_MYC_TARGETS_BURKITT_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35001076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17337
Body fat distribution (trunk fat ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.02218
BRD-K81997160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07664
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83305
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44602
BRD-K07836769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33898
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0657
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91843292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39401
BRD-K45400577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08469
BRD-K28814368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3359
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88086273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57121
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43368
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.541
BRD-K78306305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58423
WW domain binding	GO Molecular Function Annotations 2025	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0653
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.566934
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.652366
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BAY-11-7085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20266
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34773
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02823
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9164468-13073_2022_1056_MOESM1_ESM.xlsx-S7_ARNT_alteration-hgnc_symbol_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21835
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16296
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0425
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18578
VRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10497
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38798
PMC9580020-tx2c00131_si_004.xlsx-Fig_5B_data-TABLE_S3_CORE_GENE_TARGETS_HSF1_KOVACS_ET_AL_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.38684
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6013
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5089
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16217
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31149
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20119
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36333
BRD-K76680796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25803
BRD-K21620541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1156
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
psn1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
8816_TELO2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.569132
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0834
BRD-K13076765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59528
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39314
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65868510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00737
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03534
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8605
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50529
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128563_2_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07701
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13598
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79862
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8824
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49819
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53771043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46591
BRD-K75224334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47135
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05839
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A20256229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27379
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LM6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.022
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11472
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70945620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03258
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99807388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05993
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52256
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83692
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19825
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76384
6024_PABPC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.564727
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38822
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45782
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ctv1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43215
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70530990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34346
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_3_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0285
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14399036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18435
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57238
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77246148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64672
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240444_2_v_3_idasanutlin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48052543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54898
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-hNSCs_SATB2_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60728944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20712
7501_RPS13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.583411
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80746
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20942146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20319
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44906
bae1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
2747_ESYT1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.903766
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.191
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5378
BRD-K62597218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35412
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04532
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85625
BRD-K08036779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06661
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16853
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1449
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7824
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.7591
BRD-K77214724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14262
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4395
BRD-K12460566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18956
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21258
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22786
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15932
BRD-K59841546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87373
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175683_3_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42019
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58323923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15824
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25995
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76482408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30295
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	237.699
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38120474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32656
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18021
GSE231891_5_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10698156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21257
BRD-K32418104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32187
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87655
BRD-K44722555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26991
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2709
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25351
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04153
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63186
BRD-K42465630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03896
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79946769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01177
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09293
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.4152
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05562
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17142
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5059
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5732738-oncotarget-08-103415-s002.xlsx-MFC-7_DEGs-Genes_with_significantly_different_expression_between_parental_MCF-7_and_GATA3_WT_clones_with_adjusted_P_value_0_05_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150634_1_v_0_cd28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2038
BRD-K87080232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02578
BRD-K91628074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00191
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8973
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6248
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87039
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	234.697
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07788
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_ZR75_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3942
BRD-K87884409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50969
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18429
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	203.188
BRD-K06284373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11666
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32535831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02134
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K91269812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00906
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10534007-Table_3.xlsx-S7_unique_up_MSC_V-312_elements_included_exclusively_in_VMCUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9961
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10641
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202587_1_v_2_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A99402294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14064
BRD-K22591777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83241
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34831
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2169
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25379
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2105
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81752
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61347
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28902
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9580020-tx2c00131_si_003.xlsx-Fig_5A_data-HSF1_KOVAC_same_dataset_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45039
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
BRD-K60713831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2404
GSE239578_1_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01677
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40909
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27725
nucleotide-excision repair factor 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45822
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68895
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26421
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64763803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67973
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5139
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23075656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65561
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.169
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75853175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08791
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72687327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89424
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9805
T cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE227634,GSE228381_0_v_5_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymph	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02337960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33958
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73206088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04622
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2622_EMG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.722687
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.949
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77743611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98657
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16255400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10627
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
BRD-K05479183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62108
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1995
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01266518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42588
BRD-K07914894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61666
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94464
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5806
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
BRD-K27008344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20505
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12865
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4652
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.45668
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08747
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.83665
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00201
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.4623
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10787
BRD-K42776812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49936
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3673
BRD-K65320638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68854
BRD-K56943789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45428
U2-type prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
BRD-K61733751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09566
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
la4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37866276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72173400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41641
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11922
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01905
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22063616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36732
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93945680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43371
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4414
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01494
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54339
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02889
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29702569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95208
BRD-K38211037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88455
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47073
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26172
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K69487461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14866
anisomycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49517
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41929
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17741
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0545
BRD-K36709933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64644
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61432
BRD-K31844308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2446
BRD-K47878187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83889
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_ZR75_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74500173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09422
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95345
BRD-K64066545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1291
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27711
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.33979
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	0.927398
BRD-K56283394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67297
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WICH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18286
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.847
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05436
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2916
BRD-K01660763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31967
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.268
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56533
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16322
PMC6543837-Table_9.XLSX-In_vivo_M2_LPS--Supplementary_Table_9_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116580_0_v_1_smug1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WRL-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
BRD-K03141963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32133
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25625
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22913
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00568
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-down_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02963
BRD-K25583354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85907
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13044705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05229
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76895
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12322
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04244
BRD-K53774864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91305
GSE227592_9_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.205
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77718491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70308
BRD-K24494475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71644
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31267
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.566
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	6.67822
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44853
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6889
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Protein quality control and DNA repair	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Ppes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
BRD-K74968522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74274
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88233
BRD-K73039647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67711
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32199799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3056
BRD-K71368065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1556
6396_PKM_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.561062
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.819
BRD-K45073068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14099
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78947
BRD-K73459389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08041
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8433
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	1.04201
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37819
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98551
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84452
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53524
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7594
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31163
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35121
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22878
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05163
BRD-K86593041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06591
BRD-K29298614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15872
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79697020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02042
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75730049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19554
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9641
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33967062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28169
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19781
BRD-K94881465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3635
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89767_4_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31623
BRD-K78493876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3056
BRD-K49903196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5251
BRD-K71607378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27798
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45245
BRD-K32477623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26188
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.9157
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12328371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66478
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27239
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62699
chr1_155252386_C_T_b38	GTEx eQTL 2025	1.0	1.15397
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56203
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02038
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.5259
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7024_RAB32_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.535514
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.796232
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45133
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mdamb157	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62207
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
9857_WEE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.754767
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12991
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50926
GSE239578_2_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30539
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35785
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22903
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8143
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
10400_ZNF497_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.51541
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4113
homatropine-methylbromide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73614
BRD-K76544773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03896
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.9355
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03235
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02071
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40456
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-26-ZNF81_ZNF81	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5596
t62-spleen_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-4.70812
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.6565
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06394
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
efm19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
BRD-K59324446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79527
BRD-K89300187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47252
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19142902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78033
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14721
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21706
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27636
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_PD98059_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138289
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63545
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09497
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8913
BRD-K69705285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08308
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27942
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39858575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.46395
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08852
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37149438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33914
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.81072
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09908
PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Binding_Sites-Unnamed_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_HepG2_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82292504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43409
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31748
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35836
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03048
Cortical surface area (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14707
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09414
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8452
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01964
BRD-K29908513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29631
BRD-K18515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03156
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4409
10184_ZNF174_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.718376
BRD-K85066228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38438
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.483
BRD-K00381858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26537
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03434
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85943
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A90969585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29615
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
4349_PRORP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.612877
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65789
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-HEP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45894579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72123
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73841784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70148
Psoas major	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.054
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03194507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41765
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229978_4_v_2_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K25525067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10539
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.92608
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16026
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47966145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40423
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.8244
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71801719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83315
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3628
BRD-K59095205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38878
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1266
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72609445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51504
BRD-K90255725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36126
BRD-K35588268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5228
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0477
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3645
BRD-K77894681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17754
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.343
BRD-K64075179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5485
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78365192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7024
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
BRD-K71807663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29229
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43408
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25273
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83439
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65108634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25744
BRD-K67042874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58871
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
GSE111247_14_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92134254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10541
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88620071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55702
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09578
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81928
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35131
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23119
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.68014
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00317
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47164766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83329
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7421
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24397
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12080576-ijmsv22p2419s1.pdf-2-MECP2_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.9285
BRD-K93197397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42239
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cortical thickness (min-P)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38713
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27547
BRD-K63155804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59577
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84581
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39193666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31066
BRD-K67491390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5474
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27345
PMC10550956-41467_2023_41912_MOESM4_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_MR_and_colocalization_analysis_for_gene_expression_in_lung_and_COVID-19_outcomes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.75865
BRD-K62325456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96924
BRD-K54732353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26853
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lm8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08716