association dataset threshold value standardized value paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14629 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 GTEX-T6MN-0826-SM-32PM4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20941 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.6323 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70742 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49682 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03414 IZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17798 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828762 ICE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43479 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7343 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.4712 EIF3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56231 NSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01726 biological_process GO Biological Process Annotations 2015 1.0 null CORO1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11774 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.112336 PYCR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1783 Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pelvic varices DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.515 MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22157 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832823 AR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41344 mantle zone of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71629 GTEX-PWN1-2426-SM-48TDD GTEx Tissue Sample Gene Expression Profiles 1.0 0.846568 laterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28651 Reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30302 PTPN9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74973 periventricular stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15187 1321N1 CCLE Cell Line Gene CNV Profiles -1.0 -1.46319 cytoplasmic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20042 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41487 ARFGEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18218 RNFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1135 GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.16302 calcium ion-dependent exocytosis GO Biological Process Annotations 2015 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910384 Medial preoptic nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38491 Accessory sex gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.063 genomewide GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06271 CTAGE15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32053 Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-01A-31R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HCC364 CCLE Cell Line Gene Expression Profiles -1.0 -1.58203 MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4211 TWIST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35754 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.02717 CMPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10269 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07544 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28413 Brain Lower Grade Glioma_LGG_TCGA-HT-7855-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1404 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47687 PSORS1C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 ZNF552 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68176 GTEX-X4EP-0011-R2B-SM-3P625 GTEx Tissue Sample Gene Expression Profiles 1.0 0.901637 Tegmental reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56145 RPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51663 globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17958 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00399 medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3412 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72117 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.775 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 1.43968 NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8585 RNASEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75488 Lung squamous cell carcinoma_LUSC_TCGA-37-3792-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13543 STX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38742 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.20493 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -2.61358 Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RRM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02991 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34662 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.9663 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056303 MTFMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3047 HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -2.32528 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.866674 Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.29 HSCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18912 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18424 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074426 outer acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.96285 ZNF471 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49761 Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0845 Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74729 dexamethasone_mus musculus_gpl5137_gse10900 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null long insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39936 NUGC4 CCLE Cell Line Gene CNV Profiles 1.0 1.62652 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23995 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6127 posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.962926 PMC4424395__F6 PFOCR Pathway Figure Associations 2023 1.0 null Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.156 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.79726 Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9729 m2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0357 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.18796 GSE147959,GSE147960_5_v_3_stat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cytoplasmic vesicle part GO Cellular Component Annotations 2015 1.0 null adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056943 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.377245 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.88579 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70861 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01691 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32236 ZBED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57685 salivary gland HPA Tissue Gene Expression Profiles -1.0 -0.853404 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.85989 HCC38 CCLE Cell Line Gene Expression Profiles -1.0 -1.53183 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.6278 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172201 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null m1 part of parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42986 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7162 Water vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.35 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055227 METTL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5624 Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30942 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.11418 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100376_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00678 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045983 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4798 ZNF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33804 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.167 USP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05165 Cervical epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.582 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65517 Perturb_1112_KO_Vcan_SRP167386 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.71476 VPS33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03458 FBXL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03697 GNRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79704 DAN-G COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 basomedial nucleus (accessory basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14349 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63714 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054722 HNRNPUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00588 GTEX-PVOW-1026-SM-2XCF9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03675 BBS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63317 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46626 ZNF248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5819 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.3918 SMG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50819 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased fertilization frequency MGI Mouse Phenotype Associations 2023 1.0 null Superior central nucleus raphe, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32301 FOXP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27859 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985588 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9664 UCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24427 Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24853 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31586 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-GH-A9DA-01A-21R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33334 Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null leaf lamina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.638404 NMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70284 FGFR3_knockdown_173_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.82864 Lung adenocarcinoma_LUAD_TCGA-44-A47G-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-19 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60295 TOPORS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74634 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.28008 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9212 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04107 Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYAE1 DepMap CRISPR Gene Dependency 1.0 3.8535 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12415 cystitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.826999 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.569 NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GPR143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07136 MAPK1_knockdown_131_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.88897 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847218 mRNA_TUBA1A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PELI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9979 LC4-1 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 MAJIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83239 m1 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39174 GTEX-POMQ-1426-SM-3P61D GTEx Tissue Sample Gene Expression Profiles 1.0 0.839819 HAPLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96248 TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -2.62079 GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 0.960719 Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.78691 KG1C CCLE Cell Line Gene CNV Profiles 1.0 1.36567 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94087 vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14053 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.395 MHHCALL4 CCLE Cell Line Gene Expression Profiles 1.0 1.74594 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054094 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45144 leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.143833 acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.682463 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054294 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10541 EZH2 ENCODE Transcription Factor Targets 1.0 null UMUC11 DepMap CRISPR Gene Dependency 1.0 3.20532 GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.10144 Lung squamous cell carcinoma_LUSC_TCGA-21-A5DI-01A-31R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null RUVBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3101 DNAJC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58217 MAN2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39893 mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22659 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTK7_KD_GSE50138_674_human_H1299 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.74794 496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02866 KHSRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90412 p1 part of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59242 Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11735 OGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74179 GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles 1.0 0.862993 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21691 GTEX-XOT4-1426-SM-4B65T GTEx Tissue Sample Gene Expression Profiles 1.0 1.39467 cSARS Bat SRBD_54Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.37348 Secretory vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44636 cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null Awn TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.381 CD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7503 C1orf210 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45569 acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 cervical adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.150848 LARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19755 PPM1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.63814 TFAP2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.477 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29768 inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47687 plasma membrane GO Cellular Component Annotations 2015 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null MAP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05567 Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPDEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57663 blood GTEx Tissue Gene Expression Profiles -1.0 -0.870441 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14953 C19orf12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19928 FGF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71699 GPR108 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44459 RPL27A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14839 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.61535 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69604 uterine cervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.466885 temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.971659 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09713 RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 2.12804 EM-2 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51003 PRAME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09836 NUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 1.74509 IAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41639 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.661 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25408 STARD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83201 IGR1 CCLE Cell Line Gene Expression Profiles 1.0 1.73448 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7183 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047329 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-QDVJ-0226-SM-2I5FV GTEx Tissue Sample Gene Expression Profiles 1.0 0.902824 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35932 MRTFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65115 KNS42 CCLE Cell Line Gene CNV Profiles 1.0 1.48573 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BN-01B-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyelitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 Diabetic Neuropathy_Sciatic Nerve_GSE11343 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.54497 TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68199 REST ChEA Transcription Factor Targets 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -0.976529 familial GeneRIF Biological Term Annotations 1.0 null principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1341 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06921 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60929 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.72968 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4563 localization GO Biological Process Annotations 2015 1.0 null DENND1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48968 HROB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46146 amniotic cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.200182 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3248 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.98661 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15625 Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm glycocalyx COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.129 ABI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85658 IRF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11256 ZC3H10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76665 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null 17483317-TableS4 GeneSigDB Published Gene Signatures 1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7234 WDR5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63597 ASXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.23051 Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3494 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.81167 RICTOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52878 IGROV1 CCLE Cell Line Gene Expression Profiles 1.0 1.37638 tobacco use disorder GAD Gene-Disease Associations 1.0 null Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39433 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 CCDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15518 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.7166 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828762 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3353 H1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1114 SNX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76902 SPPL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12843 MYC ENCODE Transcription Factor Targets 1.0 null Germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.947 MLLT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91003 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044008 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0096 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.5002 BBX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43136 outer acrosomal membrane GO Cellular Component Annotations 2023 1.0 null RAD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02079 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1047 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.842378 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5706 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.930824 NPIPB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12422 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.726 m2 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13306 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.330966 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.0051 GPATCH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32921 HIPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32087 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5756 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6257 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM216A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34933 PTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96516 t69-brown-adipose_male_2w MoTrPAC Rat Endurance Exercise Training 1.0 1.42636 GTEX-NFK9-0426-SM-2YUNK GTEx Tissue Sample Gene Expression Profiles 1.0 0.923134 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94623 VASH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57152 GTEX-XMD1-0826-SM-4AT52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15987 Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64685 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1111 CXXC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06617 dorsal part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69268 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.921845 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.4507 superior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13696 carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056569 PPP3CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99827 H2722 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26824 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15148 Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07896 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0795 Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06061 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00259 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.44294 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.50816 vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063095 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CGRRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20534 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.06243 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF639 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01076 HELLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6043 COL4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30127 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16427 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.79552 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306805 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.83903 cellular component organization GO Biological Process Annotations 2015 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3696 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868662 Varicose veins DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828762 GSE229671,GSE229673_2_v_1_yrdc_human RummaGEO Gene Perturbation Signatures 1.0 null COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 acrosomal membrane GO Cellular Component Annotations 2025 1.0 null Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.175 WRAP73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38864 Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCDHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12409 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67621 TMEM231 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25074 Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.79308 SK-MEL-5 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 SW1783 CCLE Cell Line Gene Expression Profiles 1.0 1.36334 FKBP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95318 Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26213 MXD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.98131 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38771 red nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.886267 SOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.99377 NCIH2030 CCLE Cell Line Gene Expression Profiles -1.0 -1.46162 PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null SFT2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01447 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null YIPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6571 HELT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53669 B3GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11878 Outer membrane protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.938 HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.87909 globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.82396 SH3BP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21756 GSE244072_11_v_1_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null SRSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41528 NTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79227 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISTMES2 CCLE Cell Line Gene CNV Profiles -1.0 -2.07067 IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88158 basal peduncular hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24954 Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6789 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SNCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25335 Cystitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.67 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8751 ZNF519 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75528 B9D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03284 AK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90195 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24379 NCI-N87 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 Obesity-related traits GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 Sperm head-tail coupling apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.742 early endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.273 Secretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.928 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.76515 medial subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22623 nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24502 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83869 PEX14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0835 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00859 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.17114 Zona pellucida receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.991 C2orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00212 RL CCLE Cell Line Gene Expression Profiles 1.0 1.59292 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PP-2026-SM-3P61N GTEx Tissue Sample Gene Expression Profiles 1.0 1.05976 hela cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.588832 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3320-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.035 GTEX-N7MT-0126-SM-2D7VT GTEx Tissue Sample Gene Expression Profiles 1.0 0.907575 GTEX-Q2AG-0626-SM-2S1PV GTEx Tissue Sample Gene Expression Profiles 1.0 0.864728 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles 1.0 1.26543 Prostate adenocarcinoma_PRAD_TCGA-G9-6494-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.972759 Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5222 THBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17429 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 0.90718 Lung adenocarcinoma_LUAD_TCGA-55-6983-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAOV4 CCLE Cell Line Gene Expression Profiles -1.0 -1.49167 Hyperphosphatemic familial tumoral calcinosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.562 PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88965 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.40566 lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62159 Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QT-2026-SM-3NMCJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.833194 OVKATE CCLE Cell Line Gene Expression Profiles -1.0 -1.97099 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4172 GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles 1.0 0.824237 lateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18282 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79896 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7276 spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.55607 SP140L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11123 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04039 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873425 anterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3693 FBXL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68605 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bounding membrane of organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.003861 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GJ-01A-21R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074328 Prostate adenocarcinoma_PRAD_TCGA-EJ-8474-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0213 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86922 RASL10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56579 transport GO Biological Process Annotations 2015 1.0 null impaired fertilization MGI Mouse Phenotype Associations 2023 1.0 null BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.2821 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2588 DOHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42804 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.81869 SNU620 CCLE Cell Line Gene CNV Profiles 1.0 1.35421 p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53958 UBE2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1207 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.2864 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H290 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 SEPTIN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90206 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15664 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.904848 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06434 pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22202 ALOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85915 intermediate stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22252 GTEX-U3ZM-1126-SM-4DXUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.19848 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055717 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30965 PRRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10822 cell part LOCATE Predicted Protein Localization Annotations 1.0 null dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29745 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4158-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.274 CREB3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18122 Asthma_Epithelial Cell_GSE4302 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.22885 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52063 m1Lim (VL) part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04269 Curli COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.119 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25259 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01483 mantle zone of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21105 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07492 PIP4P1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7264 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIK3R4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2822 Lung squamous cell carcinoma_LUSC_TCGA-21-1079-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75817 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.94088 FTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49723 GSE202587_1_v_0_xrn1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33907 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.154295 NSDHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02573 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.78565 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.184241 appendix HPA Tissue Gene Expression Profiles -1.0 -0.853404 mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12635 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.45595 skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -0.853404 Seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.227 Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.8 decreased litter size MGI Mouse Phenotype Associations 2023 1.0 null urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063679 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 67.0839 single-organism transport GO Biological Process Annotations 2015 1.0 null TP53I11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35585 periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20134 H3-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89653 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93779 EM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.82195 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910746 GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles 1.0 1.13398 ZKSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52683 MANF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44084 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 HMGXB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66079 zona incerta complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39978 fusion of sperm to egg plasma membrane GO Biological Process Annotations 2015 1.0 null GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles 1.0 0.910202 GTEX-P44H-0526-SM-2XCF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24937 Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.88796 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16779 JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.41028 Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7399 SEMA4F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88463 JAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61152 IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.74121 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08951 golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null HDAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11418 BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18498 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.498 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.833298 r4 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06238 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9862 Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.85712 GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.951947 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SURF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24453 GTEX-TSE9-0011-R9A-SM-3DB7Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.29441 LYRM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.83245 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20372 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.112 Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862938 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056235 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07254 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73038 CMTM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67707 AARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08429 Plasma membrane bounded cell projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.277 PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13347 CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846385 intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72936 membrane fusion GO Biological Process Annotations 2015 1.0 null adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.291365 DM3 CCLE Cell Line Gene Expression Profiles -1.0 -2.03524 COQ4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05616 LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.8775 GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles 1.0 0.986159 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5436 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14983 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Female accessory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.029 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00537 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24379 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.840606 TRAPPC6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37116 GTEX-T6MO-1126-SM-4DM5D GTEx Tissue Sample Gene Expression Profiles 1.0 0.825856 mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28426 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78125 Acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20282 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868032 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33837 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1346 putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4131 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59312 CELSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61909 Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56796 Pilus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.848 Sperm head plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.699 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.85072 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35448 Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41874 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.973113 SKCO1 CCLE Cell Line Gene CNV Profiles 1.0 1.55756 MSS51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72879 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3527 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9798 HCC38 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11794 sclerosis GeneRIF Biological Term Annotations 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TAF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11394 C2orf49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37016 r7 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00368 PITRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76867 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16898 Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.471 finnish GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2725-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALKBH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3968 GSE118794_0_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTNND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45724 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065784 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.0658 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 EPDR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09955 FTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71641 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53124 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9464 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.75995 TRIM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10868 PDXP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2125 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49701 organelle part GO Cellular Component Annotations 2015 1.0 null anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27767 carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25457 Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13149 PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null UBN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23518 DCAF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84745 ESR1_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.25068 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.75073 sperm part GO Cellular Component Annotations 2015 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC35B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40947 AICDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88468 Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.331 GOLGA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38285 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZP-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 1.25662 Ovarian cumulus cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.967 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.955 CCDC186 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6349 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.185777 RAB3A_KO_GDS2482_706_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Sarcoma_SARC_TCGA-X9-A973-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.98978 TRAPPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20013 Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.075 APOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39046 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4729 Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CORO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23119 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1763 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3141 IFT25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0248 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8737 RTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21441 mantle zone of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38234 GTEX-XUZC-1326-SM-4BRV2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01727 GTEX-N7MT-0011-R3a-SM-2I3GC GTEx Tissue Sample Gene Expression Profiles 1.0 0.857692 intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2878 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8061 C8G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13904 MYBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79108 Primary ciliary dyskinesia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 mantle zone of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69268 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29783 HEATR5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.7416 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24379 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Macrolide transmembrane transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.569 NCIH2052 CCLE Cell Line Gene CNV Profiles -1.0 -2.2131 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2456 GTEX-RWS6-0926-SM-47JXE GTEx Tissue Sample Gene Expression Profiles 1.0 0.88974 SP140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35356 MOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43707 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 VAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29068 cellular_component GO Cellular Component Annotations 2015 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.94679 NME6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85175 WDR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59784 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20224 CDC37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64305 FIGLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63014 endosome GO Cellular Component Annotations 2015 1.0 null esophagus HPA Tissue Gene Expression Profiles -1.0 -0.853404 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178728 SNU620 DepMap CRISPR Gene Dependency 1.0 3.07451 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TNFAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3062 Tek TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.011 Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMTC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60967 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.1489 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null Perivitelline space COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.802 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.954791 Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7035 ZNF670 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47766 ES4 DepMap CRISPR Gene Dependency 1.0 4.02537 PLEKHA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36847 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01483 MAGED4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02297 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17954 ZSCAN5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66361 Visceral mass TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.286 single-organism process GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DGKZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98087 Sperm midpiece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.95 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.59978 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04668 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43658 GSE197571_2_v_1_foxm1_human RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9579 short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27466 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8618 Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPT6-2126-SM-4B66P GTEx Tissue Sample Gene Expression Profiles 1.0 0.944531 JUN JASPAR Predicted Transcription Factor Targets 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC17A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5645 SDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12569 HPRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07963 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25088 FOXP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.26343 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.846201 MAP7D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00905 Curli secretion complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.344 TAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71659 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1021 ACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74478 inferior frontal gyrus, orbital part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963853 single-organism localization GO Biological Process Annotations 2015 1.0 null GSE155852_0_v_1_apigenin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13891 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2816-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.59 CCAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57115 Bunina body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.593 ovary GTEx Tissue Gene Expression Profiles 1.0 1.57912 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.324605 amniotic fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.475423 ACBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7175 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7073 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99948 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.0423 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161139 fetus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086541 TNFRSF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.14386 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08218 LRATD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1165 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -2.75724 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.81113 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4124 Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.90779 seedling TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134362 Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.85 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.92428 rostral zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40274 GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11531 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.87171 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7363 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0158 early endosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52968 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MED24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95572 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18396 Varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.647 KCTD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27519 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.77688 lateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11608 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5638 KYO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.46372 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18872 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7898 inferior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868623 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00481 CENPW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82464 Equatorin InterPro Predicted Protein Domain Annotations 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20224 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21839 GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06485 SUPHD1 CCLE Cell Line Gene Expression Profiles 1.0 3.40815 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1628 IHF-DNA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.433 NSUN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60662 GAPVD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42448 TONSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93496 Paroxysmal nonkinesigenic dyskinesia 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.239 UBAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75721 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055405 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE77795_2_v_1_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null XPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09316 brain HPA Tissue Gene Expression Profiles -1.0 -0.853404 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.49131 GSE166169_2_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null REEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88365 diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.705144 RSV-A2_24Hour-KO_RSV_None_GSE18170 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.9886 MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.59944 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38779 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 single-organism membrane fusion GO Biological Process Annotations 2015 1.0 null GTEX-RTLS-0226-SM-2TF5E GTEx Tissue Sample Gene Expression Profiles 1.0 1.23647 primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.184137 PLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26942 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44151 NCI-H2052 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0087 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.844804 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09773 ANO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98517 Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23184 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03785 Brain Lower Grade Glioma_LGG_TCGA-QH-A86X-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plumule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.140867 secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.315586 GTEX-XGQ4-1326-SM-4GIDU GTEx Tissue Sample Gene Expression Profiles 1.0 0.945832 Perinuclear region of cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.828 RPUSD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13238 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31651 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4722 Sarcoma_SARC_TCGA-WK-A8XO-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.0 PIGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78843 sperm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.112735 Superior central nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59701 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0915 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17313 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.78119 PMC9724253-12920_2022_1407_MOESM1_ESM.pdf-144-ELK4_ELK4 Rummagene Transcription Factor Associations 2026 1.0 null layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13485 CSTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47677 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.4827 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23737 Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3971 Lung squamous cell carcinoma_LUSC_TCGA-21-1070-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventromedial hypothalamic nucleus, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11794 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.962926 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.6667 BC3C CCLE Cell Line Gene CNV Profiles 1.0 1.34846 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859217 CERS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20788 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865543 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.25 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41975 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.13752 RGL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20384 GSE228413_2_v_3_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sperm connecting piece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.057 Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.83718 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QXCU-0326-SM-2TC63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09449 t69-brown-adipose_male_4w MoTrPAC Rat Endurance Exercise Training 1.0 2.16152 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21475 Secondary motor area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76955 ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.131201 KLHL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70287 OPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47038 RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04991 PTPRU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59787 PCDHB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53061 RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3812 intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48007 SLC43A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55959 lateral GeneRIF Biological Term Annotations 1.0 null ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2617 TMEM131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12845 Cutaneous Melanoma DisGeNET Gene-Disease Associations 1.0 null GTEX-XPVG-2726-SM-4B66W GTEx Tissue Sample Gene Expression Profiles 1.0 0.913746 TMEM143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05978 Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null left atrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.597263 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23357 NCI-H2722 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900119 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.2812 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8535 HOXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83705 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0643 GEMIN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43431 GTEX-UPIC-1126-SM-4IHLO GTEx Tissue Sample Gene Expression Profiles 1.0 0.824136 NUP54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37704 MNAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66475 early endosome GO Cellular Component Annotations 2015 1.0 null SET2 CCLE Cell Line Gene CNV Profiles -1.0 -1.40368 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25807 inner acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 pulmonary vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.981518 IGR1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 POU5F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52164 KMH2 CCLE Cell Line Gene CNV Profiles 1.0 1.4469 GTEX-N7MT-0011-R2a-SM-2I3GI GTEx Tissue Sample Gene Expression Profiles 1.0 1.04594 Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU466 CCLE Cell Line Gene CNV Profiles -1.0 -1.78075 GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.9428 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900119 IGR-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.14703 GTEX-WZTO-0426-SM-3NM99 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21862 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.189378 Occipital pole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.619 acrosomal vesicle exocytosis GO Biological Process Annotations 2015 1.0 null r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79718 Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3057 OVCAR5 CCLE Cell Line Gene CNV Profiles 1.0 1.39865 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.872387 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.094337 placenta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.103682 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47741 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8929 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039206 Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Axonemal central apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.6 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01402 Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30942 Sarcoma_SARC_TCGA-K1-A6RV-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SUPT1 CCLE Cell Line Gene Expression Profiles 1.0 2.3353 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01002 EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24505 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10541 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.092 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.67737 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vaginal epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.825 Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23744 leaf base TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.55843 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 STAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22346 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7758 CHST7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.87615 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CYSRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53232 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900119 ACLY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37287 Male pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.334 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47741 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32361 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.84968 mast cells BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.878994 RAB21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83252 Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.357 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07872 SMIM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15981 DENND4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1622 Acrosomal vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Bulbourethral gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.318 VPS25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90708 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28389 Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.357 Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.764 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.8555 hypocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.138947 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.6309 nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34394 DNAJB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60007 Motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.663 U-118-MG COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 membrane part GO Cellular Component Annotations 2015 1.0 null DLGAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18473 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21475 ovary HPA Tissue Gene Expression Profiles 1.0 1.0038 Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23184 Sperm fibrous sheath COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.178 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.56348 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.09938 JHOS-4 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 establishment of localization in cell GO Biological Process Annotations 2015 1.0 null Scrotum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.96507 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4414 RNF185 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85169 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4456 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41132 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847218 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11559 SAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19983 H2AZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42913 ERBB2_druginhibition_7_GDS2139 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.65845 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47741 YAPC CCLE Cell Line Gene CNV Profiles -1.0 -1.69283 L3MBTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2108 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36867 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Lung squamous cell carcinoma_LUSC_TCGA-77-8138-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.068 GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.46936 GLB1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94682 WNT5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00829 HSDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36393 LAMA84 CCLE Cell Line Gene Expression Profiles 1.0 1.53065 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70126 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 1.25569 RSPRY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6583 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.2114 LCLC-103H COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.441 GTEX-S7SF-1326-SM-4AD4P GTEx Tissue Sample Gene Expression Profiles 1.0 0.898002 ABL1_knockdown_137_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.96644 Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.3373 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.85341 Sarcoma_SARC_TCGA-SG-A6Z4-01A-22R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 27.5222 PSEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88989 intracellular organelle GO Cellular Component Annotations 2015 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054293 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14891 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1263 GB-1 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 ZNF549 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36171 SNU620 CCLE Cell Line Gene Expression Profiles 1.0 1.58876 DVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13396 HOOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7479 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.23564 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01483 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056125 DPH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59607 LMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65476 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231102 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6037 HOXC9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6223 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.99806 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051137 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90316 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57092 NKX1-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32713 HMGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92689 Linear nucleus of the medulla Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08789 GATA3 ENCODE Transcription Factor Targets 1.0 null membrane organization GO Biological Process Annotations 2015 1.0 null ATP5PB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82158 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11169 TMC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21365 CUTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97567 vesicle-mediated transport GO Biological Process Annotations 2015 1.0 null HRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50482 KLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32364 GTEX-N7MT-1426-SM-3LK5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.0421 Lateral dorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05485 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47873 PARD6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18556 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.45999 chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 MLST8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57193 substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06424 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40722 fetal membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084739 MEGF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72004 Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPFIA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53885 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48934 locus GeneRIF Biological Term Annotations 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14953 inner acrosomal membrane GO Cellular Component Annotations 2023 1.0 null DTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94929 SIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67083 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.6732 NDUFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20536 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adult asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 Implantation fossa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.988 GTEX-TSE9-2226-SM-4DXUR GTEx Tissue Sample Gene Expression Profiles 1.0 1.16544 Biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.992 TACC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31252 periplasmic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.270434 GTEX-UJMC-2026-SM-3GADR GTEx Tissue Sample Gene Expression Profiles 1.0 0.948738 RPS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35143 Epithalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3145 GPKOW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03336 GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01207 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06007 ZNF343 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92054 GTEX-R55D-0926-SM-3GAEU GTEx Tissue Sample Gene Expression Profiles 1.0 0.890805 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5737 MRPL51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93358 cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.679 JHESOAD1 CCLE Cell Line Gene CNV Profiles 1.0 1.47341 Perinuclear theca COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.353 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.62311 hsa-miR-412 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 VAPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32708 membrane GO Cellular Component Annotations 2015 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50506 mRNA_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null RBM27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30643 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GOLGA8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80785 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79718 RERFLCAD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48211 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16087 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null CCDC22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36261 bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.781479 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Female pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.043 IFT80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53331 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.07751 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.83 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.446 SCARB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89102 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7429 GTEX-T2IS-0526-SM-32QP9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.883841 TESK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29127 cytoplasmic vesicle membrane GO Cellular Component Annotations 2025 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04119 Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C15orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87071 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HP-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-0011-R2A-SM-3P5ZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.1852 H-NS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.388 LBH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77006 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24448 ZZZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78927 NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 1.64456 HCC70 CCLE Cell Line Gene CNV Profiles 1.0 2.06817 secretion by cell GO Biological Process Annotations 2015 1.0 null DPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68674 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.35486 cervical carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.111489 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49266 VZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36753 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21545 heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079527 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.04539 VPS37D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95311 SLC2A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40769 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040738 SDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8462 EHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90618 cytoplasmic vesicle membrane GO Cellular Component Annotations 2023 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15148 NELFE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72539 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40602 CAMK2N2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96251 ROS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.672 YAPC COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures 1.0 null Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.243 MCM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05929 HS863T CCLE Cell Line Gene Expression Profiles -1.0 -1.93616 head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.879711 SNU738 CCLE Cell Line Gene CNV Profiles -1.0 -1.65875 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8869 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.37212 GTEX-S4UY-0726-SM-4AD6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.908177 GTEX-WYVS-2426-SM-3NMA9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13559 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.931437 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 2.22503 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.488 U118MG CCLE Cell Line Gene CNV Profiles -1.0 -1.4071 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847218 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.80821 cytoplasmic vesicle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3035 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.32121 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14983 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85372 GTEX-V1D1-2226-SM-3NMAX GTEx Tissue Sample Gene Expression Profiles 1.0 1.10065 EPB41L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97883 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940688 Pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.413 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC7A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77075 GTEX-P4QT-1426-SM-3NMCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.890096 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.821 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2232 UBXN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62575 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null TMEM165 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52885 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23491 GTEX-XQ3S-0926-SM-4BOPI GTEx Tissue Sample Gene Expression Profiles 1.0 1.19287 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null SLC25A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1521 plant embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134362 NCIH2342 CCLE Cell Line Gene Expression Profiles 1.0 1.8935 Radial spoke head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.235 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TALDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36796 UCKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16391 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51162 secretory granule membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 ANAPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20518 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59728 NCO2 CCLE Cell Line Gene Expression Profiles 1.0 1.84774 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.901978 fusiform gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42943 IZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02038 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.08835 Secretory granule membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Peroxisomal importomer complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.833 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2251 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.59276 TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5738 RAF1_overexpression_220_GSE42964 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.74419 Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.131201 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82939 upper basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00533 SHOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15622 TCF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81716 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3683 GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 DPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69331 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87999 Superior colliculus, motor related, intermediate gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00795 Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFDN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55019 single-organism membrane organization GO Biological Process Annotations 2015 1.0 null WRAP53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67093 inferior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.950918 CASC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92679 PSMB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7255 GSE101546_2_v_4_setdb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13276 GTEX-U8T8-1226-SM-4E3IH GTEx Tissue Sample Gene Expression Profiles 1.0 0.870849 Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07957 NRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07055 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMK2G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87096 organelle LOCATE Predicted Protein Localization Annotations 1.0 null NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null RCOR1 ChEA Transcription Factor Targets 1.0 null Epididymal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.946 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039299 H3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98491 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF816 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.287 GTEX-X8HC-0626-SM-4E3HQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.06382 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51003 CETN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.77732 Superior colliculus, optic layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33865 GTEX-TMMY-1726-SM-4DXTD GTEx Tissue Sample Gene Expression Profiles 1.0 1.01766 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36596 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2709 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3704 SETX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53163 Perturb_15654_OE_Rv3722c_SRP279962 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 stipule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.80564 LRRC57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73521 EBAG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73732 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.837911 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.13083 496100360_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42657 intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50315 20140255-TableS2 GeneSigDB Published Gene Signatures 1.0 null EW7 DepMap CRISPR Gene Dependency 1.0 2.10973 GNG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01016 NFRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44868 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intermediate stratum of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40274 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 122.825 Sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.265 secretory granule COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 liver HPA Tissue Gene Expression Profiles -1.0 -0.853404 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABHD17C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25221 RAB33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11228 ZNF558 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38331 Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 cytoplasmic membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27611 lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2448 GTEX-RTLS-2326-SM-46MUH GTEx Tissue Sample Gene Expression Profiles 1.0 1.31279 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2364 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.21424 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32738 GTEX-X5EB-2526-SM-4E3HY GTEx Tissue Sample Gene Expression Profiles 1.0 0.862358 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.8548 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZCCHC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47826 E2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71752 Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90053 P30-OHK COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BSDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99994 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847218 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.69619 NXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36633 inner acrosomal membrane GO Cellular Component Annotations 2015 1.0 null ANKRD23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27075 Vein disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.285 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 177.443 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67445 Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF790 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54608 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.7581 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54509 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11169 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.72551 OGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61361 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33828 SW1088 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 ESR1_T47D_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.49246 FAM170A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97593 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.4126 dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22512 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.5873 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0102 SELENOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23882 ABL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30488 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15686 Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06955 Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MIS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57969 establishment of localization GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71135 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934497 NCIH1838 CCLE Cell Line Gene CNV Profiles -1.0 -1.54483 GGN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47933 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859217 GTEX-QDT8-0926-SM-32PL2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.934943 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32269 SERF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.4072 RPL26L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22777 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77247 population GeneRIF Biological Term Annotations 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0413 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1656 GABBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50826 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12751 intermediate stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54267 ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48955 LIN54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47384 NUDT18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79543 extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Secretory granule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 FNDC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13707 ITPRID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05761 Ooplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.88 amyotrophic GeneRIF Biological Term Annotations 1.0 null GTEX-X4EO-2926-SM-4E3JH GTEx Tissue Sample Gene Expression Profiles 1.0 1.12925 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7021 pilus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.02829 all GWASdb SNP-Phenotype Associations 1.0 0.028314 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953927 DIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00667 Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64261 ZNF92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91346 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985588 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4324 GTEX-WEY5-2226-SM-3GILQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.888132 ZNF770 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52011 TLR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18674 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02362 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.1221 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859217 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37153 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54267 Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8767 PCBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01867 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21539 GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.4499 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886285 inner acrosomal membrane GO Cellular Component Annotations 2025 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4884-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tendril TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.281 HS840T CCLE Cell Line Gene Expression Profiles -1.0 -1.56705 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19175 Dynein axonemal particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.51 CEPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79192 Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4309 EP400 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73985 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.78869 TECPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24452 METTL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72314 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.55474 DMRTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27689 SUDHL6 CCLE Cell Line Gene Expression Profiles 1.0 2.11483 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.29107 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0444 KREMEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25335 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3219 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.10529 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32039 GTEX-S7SF-0226-SM-3K2BI GTEx Tissue Sample Gene Expression Profiles 1.0 1.02026 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.07155 GTEX-T5JC-0011-R2A-SM-32PLZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.858549 FXR MotifMap Predicted Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.269521 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9404 ITCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42677 integral component of membrane GO Cellular Component Annotations 2015 1.0 null cervical cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117963 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5707 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8183 intermediate stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66488 REST-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75025 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52311 GTEX-RN64-1226-SM-2TC6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.07439 Lung squamous cell carcinoma_LUSC_TCGA-52-7622-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.844679 Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAMTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17553 CDCA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75081 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11169 amnion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.140773 ZNF649 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17967 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5873 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22168 centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77964 IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61557 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79685 ZSWIM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2605 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null C1QTNF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06698 oligozoospermia MGI Mouse Phenotype Associations 2023 1.0 null OSGEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07692 endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.280349 cell part GO Cellular Component Annotations 2015 1.0 null U138MG CCLE Cell Line Gene CNV Profiles -1.0 -1.963 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03055 Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-POYW-1226-SM-2XCEP GTEx Tissue Sample Gene Expression Profiles 1.0 0.949025 GSE112860_5_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RDH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35328 intermediate stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17862 ASF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15375 ATP5F1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60978 SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74688 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.273 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.9144 PDCD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36035 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.912397 Seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.342 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.43581 TERF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39831 RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269 Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.56881 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45844 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WW-01A-22R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.88961 Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-1626-SM-4DM52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.969574 RPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49446 EB2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989589 Axonemal microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.679 PRICKLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45007 acrosomal vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36987 lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21231 testis HPA Tissue Protein Expression Profiles 1.0 2.04572 vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 cuneus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.840226 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09263 GTEX-WFJO-1026-SM-3GIKL GTEx Tissue Sample Gene Expression Profiles 1.0 1.30165 Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66716 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.28142 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88554 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMIM29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49334 RAB2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14923 Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF172 CCLE Cell Line Gene CNV Profiles -1.0 -1.89132 TET2_KO_GDS4287_430_mouse_CMP - bone marrow progenitor population GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MROH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79293 PMC4424395__F6 PFOCR Pathway Figure Associations 2024 1.0 null Anterior group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10284 RHOH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19432 GTEX-S4Q7-1426-SM-3K2B9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19711 TFIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32606 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057371 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.508 Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71135 Membrane stack COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.632 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948612 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3864 intermediate part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26367 GSDMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17401 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2501 TMK1 DepMap CRISPR Gene Dependency 1.0 6.51677 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.21775 Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.933758 MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.172977 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null S117 CCLE Cell Line Gene CNV Profiles -1.0 -1.38013 GTEX-TMMY-0526-SM-33HBC GTEx Tissue Sample Gene Expression Profiles 1.0 0.900094 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20224 GTEX-WYBS-0626-SM-3NMAS GTEx Tissue Sample Gene Expression Profiles 1.0 0.889032 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8895 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SLC25A24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65729 Anterior cingulate area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07676 ALAS2_OE_GDS2118_74_human_Blood GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cervical cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.121631 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null superficial stratum of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06424 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.51658 Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.711 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null inferior temporal gyrus, right, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.82549 nucleus subceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932622 GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26382 ZFAND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78681 Oral squamous cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.743 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31871 ventral tegmental area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.929031 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97338 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8955 PRXL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79012 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.79351 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 FSCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19424 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.975252 ZNF713 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4166 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.844773 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68311 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.928 CYP20A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96382 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4985 organelle GO Cellular Component Annotations 2015 1.0 null RNF38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90731 SLMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30909 MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14503 NB4 CCLE Cell Line Gene CNV Profiles 1.0 1.83531 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8393 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.0203 nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889325 SKA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10409 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.879127 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9846 HPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69645 SW1088 CCLE Cell Line Gene CNV Profiles -1.0 -2.25094 reduced male fertility MGI Mouse Phenotype Associations 2023 1.0 null HOXB9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1183 MEIOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52313 SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 2.55788 dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal lateral geniculate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69796 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2711 MTO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72943 Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.744 GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.25802 PPP2CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07474 dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66488 GDPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.66328 DHX34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93459 GSU CCLE Cell Line Gene Expression Profiles 1.0 1.46792 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8361 GTEX-QMR6-0011-R2A-SM-32PKV GTEx Tissue Sample Gene Expression Profiles 1.0 1.0286 ZNF226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35431 GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.16819 PCDH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10759 TRIM28_knockout_301_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.95445 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03002 GFI1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04343 U2OS CCLE Cell Line Gene CNV Profiles 1.0 1.54448 outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.453223 outer acrosomal membrane GO Cellular Component Annotations 2025 1.0 null CCNI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45941 AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85235 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.993946 Sirt1_OE_GDS2658_140_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0026 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8499 WDR18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90108 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.831556 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3919 GTEX-N7MS-0926-SM-2HMIZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07104 TMED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98354 retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88979 Chromatoid body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.771 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34936 ERCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80505 inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.854822 smoking cessation GAD Gene-Disease Associations 1.0 null LRP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07486 Endometriosis_Endometrium_GSE7305 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.74096 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03663 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0842 NCSTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08746 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042746 GSE236262_0_v_3_trim28_mouse RummaGEO Gene Perturbation Signatures -1.0 null perimammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71135 PBK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22751 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9713 exocytosis GO Biological Process Annotations 2015 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071957 PCMTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66235 FANCE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.622 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8558 Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2373 LMBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23871 SUGP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89408 RERFLCMS CCLE Cell Line Gene Expression Profiles -1.0 -1.47263 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13776 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.825122 SNUPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77579 TRMT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93588 superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19348 RRP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32051 finds GeneRIF Biological Term Annotations 1.0 null Vitelline envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.623 Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer acrosomal membrane GO Cellular Component Annotations 2015 1.0 null GTEX-WFG8-2526-SM-3GILR GTEx Tissue Sample Gene Expression Profiles 1.0 0.924704 seed TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.123133 NR2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6048 Sperm annulus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.575 vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.244232 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.019 organelle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09894 SRC_activemutant_51_GSE15815 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.98843 KCNE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16006 HLC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33622 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2426 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 DHRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45432 Acute Myeloid Leukemia_LAML_TCGA-AB-2969-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.19312 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863482 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71966 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34076 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.932816 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953927 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.732 endomembrane system COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles 1.0 0.942748 TPBGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26607 ZDHHC23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40398 KMS28BM CCLE Cell Line Gene Expression Profiles 1.0 1.3727 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 NOMO-1 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2269 MYH9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30811 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72936 NIBAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.92702 CASP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03978 mantle zone of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40274 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2213 APLP2_KO_GDS4414_371_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3234 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.886687 Egg coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.379 GTEX-RN64-0726-SM-48FCV GTEx Tissue Sample Gene Expression Profiles 1.0 1.16543 METTL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.41421 DUT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52515 GTEX-SE5C-0326-SM-4BRWX GTEx Tissue Sample Gene Expression Profiles 1.0 0.864996 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.029 superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24502 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.89702 GTEX-UTHO-0011-R2A-SM-3GIKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.45299 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66488 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.76761 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948612 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.5315 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58275 Epididymosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.052 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92683 ODF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02435 PANC0213 CCLE Cell Line Gene CNV Profiles 1.0 1.54265 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.97304 YLPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75253 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0086 CEP95 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78202 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832823 post-anaphase microtubule array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.235 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.50238 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.05289 GSE139540_0_v_1_menadione_human RummaGEO Drug Perturbation Signatures 1.0 null SPINT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01411 MDAMB157 CCLE Cell Line Gene Expression Profiles -1.0 -1.96331 HLA-E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50257 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYBS-0326-SM-3NM8S GTEx Tissue Sample Gene Expression Profiles 1.0 1.02428 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.187 Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.33 NCIH209 CCLE Cell Line Gene Expression Profiles -1.0 -1.59996 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PA-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SN8G-0526-SM-32PLE GTEx Tissue Sample Gene Expression Profiles 1.0 1.07977 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09189 m2 part of nucleus parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01323 GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles 1.0 0.990285 PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70101 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0231 peduncular subparaventricular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38234 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2795 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 ZNF367 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51658 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10702 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24379 preisthmic midbrain tectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03745 GTEX-RU1J-0826-SM-46MUU GTEx Tissue Sample Gene Expression Profiles 1.0 0.89804 GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles 1.0 0.95182 GSE148096_1_v_0_erlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6667 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 CBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49643 GTEX-WH7G-2626-SM-3NMBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.850138 NOMO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.63637 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64877 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36985 GTEX-QMRM-1726-SM-2S1QG GTEx Tissue Sample Gene Expression Profiles 1.0 0.94375 GSE149903_4_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21839 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 C11orf54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53885 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.8748 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.515749 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100431_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.31977 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07666 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6699 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2513 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 GTEX-Q2AG-1026-SM-33HBW GTEx Tissue Sample Gene Expression Profiles 1.0 1.07791 FU97 CCLE Cell Line Gene Expression Profiles 1.0 1.36834 C15orf39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00018 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.1591 EEF1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26535 Sperm mitochondrial sheath COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.002 TNPO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56582 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.959571 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7817 placental membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.922055 EFM19 CCLE Cell Line Gene CNV Profiles -1.0 -1.34226 RH18 CCLE Cell Line Gene Expression Profiles -1.0 -1.82844 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4172 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 acrosomal membrane GO Cellular Component Annotations 2023 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50253 GTEX-PWCY-1326-SM-48TCU GTEx Tissue Sample Gene Expression Profiles 1.0 1.27465 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Coagulating gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.81 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03949 HSFX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47124 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6806 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null F8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9238 AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22661 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5561 DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6159 GSE140997_4_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1681 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.992754 GT3TKB COSMIC Cell Line Gene CNV Profiles 1.0 2.14703 GSE129648,GSE129650_2_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GGA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13346 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 G84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981533 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DES_KO_GDS4804_171_mouse_young skeletal muscles GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MORC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43191 VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06768 Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15155 cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172201 Oviduct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.384 single-organism cellular process GO Biological Process Annotations 2015 1.0 null CREBRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96022 PPP1R3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8314 Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.235 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26849 Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.067558 GTEX-WI4N-1426-SM-3LK7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.909063 TTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89672 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03807 mantle zone of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26122 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19348 Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55262 bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.899558 mRNA_ZFX_17448993 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VENTX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9693 MSTO211H CCLE Cell Line Gene Expression Profiles 1.0 1.48731 AKR1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1799 MEG01 CCLE Cell Line Gene Expression Profiles 1.0 1.96191 PCDHB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10744 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6698 ZNF785 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27319 Epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.514 DNAJC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20519 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03117 Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GJD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34505 posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14742 Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.3613 Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.93607 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.28302 H2AC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88283 SOX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21902 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54979 HBS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67484 HCC33 CCLE Cell Line Gene Expression Profiles 1.0 1.61446 GSE104508_0_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null RBPMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8037 Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859248 Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.22677 endocytosis GO Biological Process Annotations 2023 1.0 null APLP2_KO_GDS4414_534_mouse_adult cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-L4-A4E6-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Axonemal central pair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.614 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4647 intermediate stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.10147 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15717 GTEX-WYJK-1426-SM-3NM8V GTEx Tissue Sample Gene Expression Profiles 1.0 1.01893 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.13333 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.5207 CADOES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.66226 Type IV pilus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.578 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57731 Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 79.3642 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11544 Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DANG CCLE Cell Line Gene CNV Profiles -1.0 -1.52822 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36159 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1106 ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59631 ZC3H14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35068 SLC6A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44948 GALNT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.80326 TTYH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8048 CENPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05935 thyroid_5c HPA Tissue Sample Gene Expression Profiles 1.0 0.844764 SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900119 periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4363 CRNKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81045 USP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44717 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01767 anterior nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18065 pontine reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02425 EVPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15378 BICR78 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 GTEX-P4PP-1726-SM-2S1NS GTEx Tissue Sample Gene Expression Profiles 1.0 0.951848 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4257 TCF7L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58384 Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.81798 shell of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09711 PNRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04007 GSE122425_1_v_0_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE231799_2_v_1_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null ESR1 ENCODE Transcription Factor Targets 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ANKRD49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84696 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null impaired acrosome reaction MGI Mouse Phenotype Associations 2023 1.0 null intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04265 DHRS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30399 KDM5A ENCODE Transcription Factor Targets 1.0 null DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7532 CAL12T CCLE Cell Line Gene Expression Profiles 1.0 2.65492 LASV_FML29_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.13033 Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52147 vesicle-mediated transport GO Biological Process Annotations 2023 1.0 null D542MG DepMap CRISPR Gene Dependency 1.0 6.56654 SNW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33929 GB1 CCLE Cell Line Gene CNV Profiles -1.0 -2.82442 GSE74490_0_v_1_triptolide_mouse RummaGEO Drug Perturbation Signatures 1.0 null atrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.3976 EIF4E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94369 primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.972686 YAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40189 FCSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56702 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.00842 Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.825 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.39 Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06892 GTEX-X62O-0126-SM-4E3JN GTEx Tissue Sample Gene Expression Profiles 1.0 1.23751 H2595 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.72629 TERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64147 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05518 HS852T CCLE Cell Line Gene Expression Profiles -1.0 -1.88776 Apical hook TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.686 CCDC96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.26992 Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75777 orbital frontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28452 GTEX-OXRN-0526-SM-2I5EN GTEx Tissue Sample Gene Expression Profiles 1.0 0.9393 SPAG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05491 UROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81978 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.15778 HMC18 CCLE Cell Line Gene CNV Profiles -1.0 -1.69229 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966813 GTEX-XV7Q-2526-SM-4BRV9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.992021 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.112 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.68684 GTEX-X4EP-2926-SM-3P5YQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.830134 Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.0306 GPM6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32434 BCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55952 GTEX-VJWN-0126-SM-3GIK7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.891362 Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19558 SW1116 CCLE Cell Line Gene CNV Profiles 1.0 2.25733 RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null 496100402_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0016 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.900863 GSE153064,GSE153065_1_v_2_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7393 FAM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0513 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9714 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.872387 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04119 GTEX-P4QS-0226-SM-3NB1U GTEx Tissue Sample Gene Expression Profiles 1.0 1.10494 MAP1LC3B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98488 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8041 PHPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79858 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063437 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246124 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18116 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5439-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE100217_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null CLDND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56056 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22995 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24042 ZBTB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22813 Vas deferens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.126 AKT1_knockdown_135_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.47495 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3173 ESRRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24153 Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.5 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13891 GTEX-UJMC-1926-SM-3GADS GTEx Tissue Sample Gene Expression Profiles 1.0 0.858803 GTEX-O5YT-0226-SM-32PK5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0872 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79206 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.017 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.82996 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06424 GSE240027,GSE240030_1_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE229671,GSE229673_3_v_1_yrdc_human RummaGEO Gene Perturbation Signatures 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052964 lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18909 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.341863 GSE166169_1_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.604 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.21953 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3919 KANK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09696 PRDM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49608 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.971 SLITRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73152 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE169571_5_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null TC71 CCLE Cell Line Gene Expression Profiles -1.0 -1.7021 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05985 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9515 FGFR3_knockdown_34_GDS4454 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.82868 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.30032 Corpus epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.346 BARX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39229 Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0786 GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.871601 Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.004 PLAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91263 GTEX-WOFM-1626-SM-3MJFX GTEx Tissue Sample Gene Expression Profiles 1.0 1.21688 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chromosome GeneRIF Biological Term Annotations 1.0 null lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.893057 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.00332 zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.0746 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XMD1-0011-R9A-SM-4AT49 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02172 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.10876 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05704 SLC25A51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26366 POLR3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7035 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65M-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92723 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.52468 SMG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3805 HSC3 CCLE Cell Line Gene Expression Profiles 1.0 1.75976 FASTKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50313 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13399 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25208 Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.881 HDLM2 CCLE Cell Line Gene CNV Profiles 1.0 1.84293 BORCS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25803 FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2546 Ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.352 GTEX-OXRO-0326-SM-33HBM GTEx Tissue Sample Gene Expression Profiles 1.0 0.971881 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -1.93874 mantle zone of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1849 FAHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00272 liminal periaqueductal gray of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01859 OSC19 DepMap CRISPR Gene Dependency 1.0 3.28085 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.45694 sperm part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.010249 endocytosis GO Biological Process Annotations 2015 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.31193 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35022 Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.526 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9954 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01067 lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69034 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16792 Postsubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10026 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27354 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CSTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19146 PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QESD-1726-SM-2S1R7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17596 dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50653 ZNF688 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.87239 GTEX-SN8G-0226-SM-4DM6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.930172 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.79612 NDUFA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5554 PLAA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.84554 Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15155 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 0.990484 TAF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31128 r3 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8134 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01398 MORF4L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82037 PJVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61496 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9883 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0888 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12327 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2386 MPDU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16912 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1453 superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01904 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.624 endosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38151 HMGCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62507 ZBTB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13369 GTF3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99215 mantle zone of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08972 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92683 MED26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70892 r1 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1413 GSE197197,GSE212981_1_v_0_carm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Seminal vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.15 Perturb_14043_KD_H2AZ_SRP073488 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -1.56804 Integrin alpha6-beta4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.793 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.1888 LCLC103H CCLE Cell Line Gene CNV Profiles -1.0 -1.37902 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.11583 Zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.318 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null secretion GO Biological Process Annotations 2015 1.0 null Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.91549 GSE92434_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08339 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09807 TBL1X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38313 PARP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60282 major GeneRIF Biological Term Annotations 1.0 null C19orf53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50049 periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34076 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.87786 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4307 ZNF491 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99115 TBX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16189 ZNF585A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58656 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OTX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51177 CL14 CCLE Cell Line Gene CNV Profiles 1.0 1.70777 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33779 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9645 ZNF468 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24236 NCIH1385 CCLE Cell Line Gene Expression Profiles -1.0 -1.48184 CPNE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46492 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9978 SCN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42733 mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92683 QDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49538 CRB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29215 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1032 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12635 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03392 medial part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21329 ZNF627 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94743 ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957963 GSE112860_5_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57603 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50653 CDY2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01231 CDK2AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48942 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085299 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1131 PLIN5_OE_GSE44192_482_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE210383_0_v_1_trim71_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06325 cause GeneRIF Biological Term Annotations 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.2123 TSEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22166 GSE118794_5_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.904505 CTNNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84713 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051615 ELMOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47673 cingulate gyrus, retrosplenial part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79903 MTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23855 Dopaminergic A13 group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65574 HT1197 CCLE Cell Line Gene Expression Profiles 1.0 1.65137 Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07834 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HVEC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.502 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.932778 ZNF331 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86301 ATXN7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91451 SPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47442 HCC1187 DepMap CRISPR Gene Dependency 1.0 4.3257 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE126127_0_v_1_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CAL33 CCLE Cell Line Gene Expression Profiles 1.0 1.90465 GTEX-X4XX-0011-R2A-SM-3P623 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834017 RRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63911 XPO7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61098 GTEX-T5JC-0011-R9A-SM-32PLV GTEx Tissue Sample Gene Expression Profiles 1.0 1.1194 TPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54361 SMAGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78798 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 2.08095 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17853 NCLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22194 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.91594 CDK2_knockdown_132_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.31392 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79718 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23528 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8158 HS571T CCLE Cell Line Gene Expression Profiles -1.0 -1.7088 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18959 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.899739 TTC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.40027 Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30288 SOX13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8719 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4925 Acute Myeloid Leukemia_LAML_TCGA-AB-2985-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L4-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.841856 CD55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31747 Pyelonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.562 NB69 DepMap CRISPR Gene Dependency 1.0 2.24862 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.8414 outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0273 CHST10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60999 DSP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5055 MCAD_KO_GDS4546_423_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CDK9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61844 inner SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.971576 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null UBXN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23421 NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 TCP10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23348 SPEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09309 Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16068 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MH-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06445 plasma membrane fusion GO Biological Process Annotations 2015 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null intermediate part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08609 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MED27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70863 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.55962 CNNM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33087 KIAA0319L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77165 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885061 GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32974 melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.18591 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02868 LB2241-RCC COSMIC Cell Line Gene CNV Profiles 1.0 2.14703 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06238 Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM181B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24489 t69-brown-adipose_male_8w MoTrPAC Rat Endurance Exercise Training 1.0 2.9344 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.2808 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.4435 intermediate stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01859 lateral group of nuclei, left, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48346 GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.15432 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72688 GTEX-WFG7-0326-SM-3GILI GTEx Tissue Sample Gene Expression Profiles 1.0 1.31833 Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-2026-SM-3GAEP GTEx Tissue Sample Gene Expression Profiles 1.0 1.24238 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null PGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54551 nucleus GO Cellular Component Annotations 2015 1.0 null membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4141 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6743 mantle zone of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00209 ARHGEF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05506 Urinary tract infection DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.234 Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.802 S-117 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4488 VSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32345 p3 portion of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10837 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29992 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80203 ZNF527 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54992 PROM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90418 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.986497 HT115 CCLE Cell Line Gene Expression Profiles 1.0 2.2588 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.08018 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68133 r4 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11049 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32296 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40974 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4159 RAGE_knockout_267_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.17432 GSE149075_1_v_0_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92683 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 LACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78201 NCAPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13215 TCF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0656 locus ceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.92609 GTEX-R55G-1226-SM-48FDC GTEx Tissue Sample Gene Expression Profiles 1.0 0.839884 KCTD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91449 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5923 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5879 ZIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26386 ATF7IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03589 GSE153064,GSE153065_1_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCCSTCK140 CCLE Cell Line Gene Expression Profiles 1.0 1.64566 SUPT3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05168 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91364 ARL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05959 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.92708 ZGRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52166 SPATC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45923 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.915313 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cytoplasmic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.21326 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0826-SM-32PMC GTEx Tissue Sample Gene Expression Profiles 1.0 0.851118 RUNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56995 GTEX-S95S-1226-SM-4GICG GTEx Tissue Sample Gene Expression Profiles 1.0 1.43618 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1838 COSMIC Cell Line Gene CNV Profiles -1.0 -2.83167 Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -1.38326 Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular process involved in reproduction in multicellular organism GO Biological Process Annotations 2015 1.0 null RPS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41909 Lung adenocarcinoma_LUAD_TCGA-62-A46Y-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.565 SFRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42675 ADCY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81167 LUC7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.830027 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057893 GTEX-WOFM-0126-SM-3MJFE GTEx Tissue Sample Gene Expression Profiles 1.0 0.924013 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23058 reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46937 habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12784 Inner acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.5068 TE5 CCLE Cell Line Gene Expression Profiles -1.0 -1.6089 Mdr2_KO_GDS1990_285_mouse_Livers of 3 month old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles 1.0 1.3344 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06434 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.25863 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09744 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1772 Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bacterial biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.117 ZBTB21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40322 Sex chromatin COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.621 GTEX-P4PP-2426-SM-3P61L GTEx Tissue Sample Gene Expression Profiles 1.0 0.847721 Outer acrosomal membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0516 GSE114284_2_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null TP63 ChEA Transcription Factor Targets 1.0 null NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4363 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.215534 GTEX-O5YW-1526-SM-3MJGL GTEx Tissue Sample Gene Expression Profiles 1.0 1.09253 m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40602 Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82111 lower dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20663 TPRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42388 Bacterial nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.233 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3934 periventricular stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03745 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6282 GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 1.15591 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0803 AKAP17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59238 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.68684 ANKRD27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80227 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.825858 FSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89922 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877733 Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.064547 Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.988 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0161 17483317-TableS5 GeneSigDB Published Gene Signatures 1.0 null JHU022 DepMap CRISPR Gene Dependency 1.0 5.73382 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8561 SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37212 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40733 Preputial gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.679 GSTM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.4829 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.994 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992518 FBXL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96241 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.3937 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02966 pi1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.95 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8799 FBXW4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43182 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR ChEA Transcription Factor Targets 1.0 null r7 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06424 RNF214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82647 Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.748 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8204 FBXO27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38802 LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.614 superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16546 Spermatogenic failure 53 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.978