association	dataset	threshold value	standardized value
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72428
G57321FI	GlyGen Glycosylated Proteins	1.0	null
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KB-88-OR49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257686
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59097
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3204
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6082
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5455971__F2	PFOCR Pathway Figure Associations 2024	1.0	null
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222601
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
PMC6316648__F3	PFOCR Pathway Figure Associations 2024	1.0	null
496100387_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4475
C4orf46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47123
Hypopharyngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22567
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394465
regulation of BMP signaling pathway	GO Biological Process Annotations 2025	1.0	null
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368544
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23948
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91202
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.9896
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09935
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.31363
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44521
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02808
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
GSE134375_3_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hemoglobin H disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95002
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of insulin receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47783
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36154
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	1.0	null
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38403
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755289
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
negative regulation of BMP signaling pathway	GO Biological Process Annotations 2025	1.0	null
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88695
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.661
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11025
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11284386__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5281
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC1S4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33878
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.738265
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64718
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207594
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48396
Erythroid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1049
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.791928
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337586
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Aceruloplasminemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24491
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1708
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.22218
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4598
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91348
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49682
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42698
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62149
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	166.818
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78915
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47933
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17455
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.7751
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604813
PMC6170398__F2	PFOCR Pathway Figure Associations 2024	1.0	null
negative regulation of catabolic process	GO Biological Process Annotations 2025	1.0	null
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243182
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
LIPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54963
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12346
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Activin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of osteoclast differentiation	GO Biological Process Annotations 2025	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.182
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56473
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261564
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70386
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
PMC5803919__F1	PFOCR Pathway Figure Associations 2024	1.0	null
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55769
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.486
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48031
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26536
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61297
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70554
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
PMC4849272__F3	PFOCR Pathway Figure Associations 2024	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.411
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48034
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5717
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
PMC6958404__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216695
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26346
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2626
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PC-18-VX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201831
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39859
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99647
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55058
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12391
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.959
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
PMC7063521__F1	PFOCR Pathway Figure Associations 2024	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.469
IC-18-TY61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200653
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
negative regulation of myeloid leukocyte differentiation	GO Biological Process Annotations 2025	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
ABCB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67532
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9771
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71598
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35669
Megaloblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
negative regulation of carbohydrate metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	167.637
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.666182
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91076
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.635
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31958
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19584
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25546
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346229
GSE140284_0_v_1_hhex_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13861
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02718
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9596
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34307
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
EE-83-WF69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201727
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09595
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25411
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2831
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07373
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.375
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24679
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10291
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24723
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334531
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.587
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8328
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34655
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34581
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7705
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74478
Sideroblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.902
PMC9331965__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484797
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06342
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01115
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
intracellular iron ion homeostasis	GO Biological Process Annotations 2025	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92351
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5973
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42092
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96796
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5141
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
ZDHHC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29469
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26885
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225753
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40944
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20512
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
Hypermanganesemia with dystonia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7817
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78506
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_up-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97575
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980421
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29714
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36372
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94237
Neonatal anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23895
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207654
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33306
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3428
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290046
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40696
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86423
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21522
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of D-glucose import	GO Biological Process Annotations 2025	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58998
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96382
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61641
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37413
PMC8164969__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dehydrated hereditary stomatocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
Diamond-Blackfan anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
PMC7306315__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91539
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12717
t55-gastrocnemius_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.30033
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40576
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02792
Hemochromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.437
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1989
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52068
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
Interferon regulatory factor 7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
FTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73472
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.824
SHOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02157
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568237
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28075
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284194
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8787
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97567
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217789
GSE189859,GSE189861_3_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4184
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	258.112
PMC7299245__F1	PFOCR Pathway Figure Associations 2024	1.0	null
regulation of D-glucose import	GO Biological Process Annotations 2025	1.0	null
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41692
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78314
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38519
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypochromic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34547
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311183
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22328
IFI30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97126
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298917
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
UT-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15003
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97769
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98672
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.864
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207914_0_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34453
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91008
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63748
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618938
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95364
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491196
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43625
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1921
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10333
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7698
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3599
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381406
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86719
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
PMC9542548__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Reticuloendothelial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91325
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45321
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.201
negative regulation of biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Polycythemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Hemosiderosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
hormone activity	GO Molecular Function Annotations 2025	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chr2_238165839_T_G_b38	GTEx eQTL 2025	1.0	9.74726
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01425
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15462
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47207
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4568
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32053
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39962
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55289
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431681
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
Sideroblastic anemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3372
RAB3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43274
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NSDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02573
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236406
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.9417
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1942
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.999217
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61697
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9237
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61897
PMC11462941-CAS-115-2947-s001.pdf-171-JDP2_JDP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Complement component C1q complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.368
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24433
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.94
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56363
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64845
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
THBD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50735
QB-72-LM87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206686
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15844
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.754
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47511
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.412
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90336
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226874
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98143
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	184.712
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
AE-09-SG21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420407
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22397
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7225
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
GSE100886,GSE100893_1_v_3_parp14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.53
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3682
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
GSE220914_2_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
DNAAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32494
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0495
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
Myotube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18858
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8537
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11743
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91592
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
negative regulation of gluconeogenesis	GO Biological Process Annotations 2025	1.0	null
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8212
Iron metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.244
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86643
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97368
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.114
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7739
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7983022__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Macrocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8824
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208999
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25069
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.5781
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211151_2_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of small molecule metabolic process	GO Biological Process Annotations 2025	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.753
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02801
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83496
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0111
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.6183
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74155
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623113
2q37 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30861
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.7963
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
GSE117212,GSE117214_2_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	174.786
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.568
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52862
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08071
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30069
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19892
Congenital dyserythropoietic anemia type IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56616
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68548
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
Hemochromatosis type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412906
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0273
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.96
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73625
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30553
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31147
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39605
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20973
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.932
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317527
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92785
PMC8901678__F3	PFOCR Pathway Figure Associations 2024	1.0	null
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06839
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1847
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88749
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3859
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19734
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5854
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53106
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45963
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98873
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.622
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17872
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735691
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00435
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.107
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.5386
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
Siderosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46393
TA-20-FO62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268431
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of D-glucose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6296
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver sinusoidal endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34523
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.746
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82097
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37155
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56251
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229175
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98583
Congenital hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.28
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
IE-80-DC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266617
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38412
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16756
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29064
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61813
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40249
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8164969__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.308
Cutaneous porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67179
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4796
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54866
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243552
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0389
Congenital dyserythropoietic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.43
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16782
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63871
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99015
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.30636
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32969
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7052
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60683
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260917
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10291819-13287_2023_3380_MOESM11_ESM.pdf-21-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68929
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13381
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94216
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1686
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07648
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00824
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29259
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61019
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39323
regulation of insulin receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23432
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47766
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73899
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88073
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5228
Hereditary spherocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01442
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26593
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67083
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7234
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69977
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22934
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital dyserythropoietic anemia type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.323
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
ZNF641	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33045
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260823
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45416
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76943
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22353
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27554
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
PMC7012465__F2	PFOCR Pathway Figure Associations 2024	1.0	null
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43175
496100513_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02425
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.12
positive regulation of signal transduction	GO Biological Process Annotations 2025	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.592734
PMC7585830__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.641
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41647
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.05229
QE-18-WG07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211589
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389091
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.292
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67919
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9147
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83454
beta-thalassemia major	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.036
Familial erythrocytosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55684
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8525
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22425
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202513
interleukin-6 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.622
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5269
PMC11001198__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
Intracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60048
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.925
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40144
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
PMC4110655__F2	PFOCR Pathway Figure Associations 2024	1.0	null
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
Pyruvate kinase deficiency of red cells	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368162
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11064
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268678
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163052,GSE163198_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23301
GSE125153_2_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97412
PMC7481169-277_2020_4194_MOESM9_ESM.xlsx-RUNX1_R174L-RUNX1_R174L_mutant_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45321
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
RNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90538
Iron deficiency anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.52
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9894
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44233
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670171
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5594
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2514
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85563
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59319
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36671
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37969
Primary polycythemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18366
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369025
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.0972
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
LIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30979
GSE129811_5_v_0_niacin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30862
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236059
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3303
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46903
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50066
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53363
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.47081
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69109
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03932
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95184
Hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.186
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77462
positive regulation of cellular response to insulin stimulus	GO Biological Process Annotations 2025	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1826
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2705
haptoglobin-hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07408
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74358
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09708
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273675
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43663
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32969
PMC4829957__F3	PFOCR Pathway Figure Associations 2024	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
CD-41-RE87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206401
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9147
GSE212772_0_v_1_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
Peritubular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254626
Reticulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.239
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61938
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96379
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302987
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19911
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60816
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39826
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01487
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7065
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6009
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299542
PMC4467862__F3	PFOCR Pathway Figure Associations 2024	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57071
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38604
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24258
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16747
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0172
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74777
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.46
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301458
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12958
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31798
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47327
PMC7519331-pnas.1921408117.sd18.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10940914-mmc4.docx-0-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
PAOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16438
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.246
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512198
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37959
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12099056-research.0703.f1.pdf-12-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61267
Ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.878
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.391
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
SH2D3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84702
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6274
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20408
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267631
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89016
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16196
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3637
GSE214823,GSE214824_4_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
negative regulation of osteoclast differentiation	GO Biological Process Annotations 2025	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.866
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35425
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40993
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AF-12-IW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307055
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47973
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14531
GSE134700_0_v_4_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03328
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22058
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12592558-41419_2025_8097_MOESM4_ESM.xlsx-downregulated_3_-_DATASET_1-RNA_Seq_analysis_upon_lncMB3_KD_in_D283_Med_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72143
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213081
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08346
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53232
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77284
PMC5903825__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.672
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57922
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of cellular response to growth factor stimulus	GO Biological Process Annotations 2025	1.0	null
Erythrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.308
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
t55-gastrocnemius_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.32799
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Pneumoconiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.15229
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8536
negative regulation of cell differentiation	GO Biological Process Annotations 2025	1.0	null
Venous blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Activin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3285
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330666
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80652
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
Marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02638
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65575
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.9601
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04097
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13581
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580778
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.141
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407777
Iron status biomarkers (iron levels)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4523
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46585
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-85-CH49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270679
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85145
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.9173
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81977
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.538
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Erythroid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.1
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8283
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00574
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3517
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4024
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13886
GSE157036,GSE166411_3_v_0_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21366
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61381
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91483
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255694
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
negative regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1014
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61111
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91323
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
QA-07-KC40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313166
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86165
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.551
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89614
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414235
FBXO34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93319
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88747
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
AF-10-BU38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297535
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36075
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.5731
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17162
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.116
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332725
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226381
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42816
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1275
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thalassemia minor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO Biological Process Annotations 2025	1.0	null
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22588
Beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.613
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.175
beta-thalassemia intermedia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60058
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58364
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
Congenital nonspherocytic hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8542
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22689
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33778
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63805
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.892
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53318
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69872
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9642
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
GFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21385
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SB-94-ZA83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317939
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.2084
DE-58-OW37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246238
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.301
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33122
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.73723
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
BMP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.609
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133516_5_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	173.264
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25933
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
AB-80-CK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329914
CTU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61868
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93614
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40557
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25865
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Erythropoietic protoporphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46168
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7184
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76769
Vitamin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32188
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27052
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37937
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mean corpuscular hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.52218
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50484
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1816
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72026
Polycythemia vera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267961
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99756
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63911
Skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78331
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27201
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90363
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44969
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.928
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93376
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38235
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86239
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84883
GSE165174,GSE165175_0_v_1_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20345
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03968
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98701
negative regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
Iron status biomarkers (transferrin saturation)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28656
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39372
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81306
AA-67-JI21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375477
PMC12077596-NIHMS2076735-supplement-2.xlsx-CRflag_RNA_NONO_TFE3-WT_UP-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34049
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361279
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66119
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60822
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5794
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	184.222
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17368
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	75.2071
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87046
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48172
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital dyserythropoietic anemia type I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3436
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.468
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62651
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198683_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of autophagy	GO Biological Process Annotations 2025	1.0	null
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4331
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-85-KE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215914
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48068
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30202
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42267
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02542
Prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84082
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.592959
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169155_6_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7519331-pnas.1921408117.sd11.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
QE-35-YE15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247734
SRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55827
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.744
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37802
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327777
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29704
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4323
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00117
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3522
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE167886_3_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.122
negative regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236232
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86574
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
PMC9266893__F2	PFOCR Pathway Figure Associations 2024	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.467
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198683_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of autophagy	GO Biological Process Annotations 2025	1.0	null
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
PMC5706455__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228125_0_v_3_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35285
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24505
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93348
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73275
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82114
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.484
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0936
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
GE-22-ME44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230005
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80397
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69777
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77623
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.711
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80393
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GSE119498_2_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267532
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76364
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22705
Intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO Biological Process Annotations 2025	1.0	null
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57637
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.599879
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96174
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pure red-cell aplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68187
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71584
GNPDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47534
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38642
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4751
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEU3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2469
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35403
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351017
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
regulation of gluconeogenesis	GO Biological Process Annotations 2025	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11001198__F5	PFOCR Pathway Figure Associations 2024	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27018
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284084
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36844
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73681
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
ED-71-GA72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208764
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28453
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40808
Mean corpuscular hemoglobin concentration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18283
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypochromic microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217014
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72793
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40305
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52834
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42544
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27214
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03093
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53885
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43405
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23497
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40928
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507772
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30391
PMC6745947__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2025	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LSM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63862
PMC8484567__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239795
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03298
Hemoglobinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
Myeloproliferative neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97774
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23822
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54858
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13804
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245599
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99543
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12077596-NIHMS2076735-supplement-2.xlsx-CR_flag_RNA_SFPQ_TFE3-WT_up-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null