association	dataset	threshold value	standardized value
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09733
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02925
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12326
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26185
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14127
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41342
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12634
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07124
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17592
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34104
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92386
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4307
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7966
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02341
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49547
CRCGN015_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55765
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61303
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84285
GNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05968
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98125
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1478
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.752
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4358
CRCGN015_MCF10A.TP53.M_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1091
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44253
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78339
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58437
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28288
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07979
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30864
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5231
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31841
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82507
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26147
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
CRCGN014_HEPG2_3H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11042
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19298
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44565
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73711
CRCGN015_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05405
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04691
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00175
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76885
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75005
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73105
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45431
CRCGN015_HEPG2_48H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12698
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22186
MSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26049
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11315
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0748
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19362
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05163
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32771
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.133
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43453
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1388
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54077
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09249
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45002
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88547
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.214
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55251
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12272
CRCGN015_HEPG2_48H:A24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30183
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79277
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62543
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.50745
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70964
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01225
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85112
CRCGN017_MCF10A.WT.HP_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31768
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27762
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11797
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25386
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24847
CRCGN014_HEPG2_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09805
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35954
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43341
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08962
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00707
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16965
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76307
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02711
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8525
CRCGN017_MCF10A.WT.HP_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1064
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89635
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3962
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18416
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40879
AURKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02634
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03985
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0916
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36933
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00033
CRCGN017_MCF10A.TP53.M_24H:E03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29307
CRCGN015_HEPG2_48H:G20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47102
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54252
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49399
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61541
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60508
BCL2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43079
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11214
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80411
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93797
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3324
RPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20653
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23804
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32249
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14867
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4314
ATAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05457
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55651
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08199
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23042
CRCGN008_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22015
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09264
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14569
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88183
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46691
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71961
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68246
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23198
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33818
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70692
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86568
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67145
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0715
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67762
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25352
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2719
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0035
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22728
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42492
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85792
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36524
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83519
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64942
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45039
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36374
BAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61878
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60956
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49704
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25483
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06071
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61459
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34652
PMC7825356-8844261.f3.docx-70-ZNF736_ZNF736	Rummagene Transcription Factor Associations 2026	1.0	null
RPS27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07481
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27375
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17513
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44049
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47076
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62175
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0794
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28085
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88944
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53626
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9471
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0993
CRCGN017_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21563
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51235
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5844
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37722
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26385
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53855
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99507
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2261
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15201
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22303
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28816
CDC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23132
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24898
TUBGCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24887
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60028
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16877
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6904
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8109
GLB1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32283
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48041